LOCUS       c00053_gnlPro..        15402 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HCNELFEG_53.
ACCESSION   c00053_gnlPro..
VERSION     c00053_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 16:21:33
            Original ID  :: gnl|Prokka|HCNELFEG_53
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15402
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15402
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2692:6163]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2693..6163
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..15402
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15402
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(15..1025)
                     /locus_tag="ctg53_1"
                     /transl_table=11
                     /translation="MKILLVTRGSQGDVLPYLAIAAELERRGHEVTINLPQIFEETVKP
                     YGFKYVLQQFDDIGGMIDSAAQNSHKFRPFLKWMRNVIDKQFDQLIPLLKEHDILVSTN
                     SEFAVASIAEYCKKPLIRTAYAPFLPGKKIPPAVLPFPKPNPIITPAILWKLMNRMTNF
                     MVKDTINKNRAKYGLAPIRNFGYHAGERSYNYLLFSQHLGNVDPDWTFEWSIGGYCFND
                     TFQYDEKAYEEMISFVDSAQSPIIFFTLGSCSSKDGNRFSKALVDICKKHDYRLIIGSG
                     WAKTGITLQADKHLFLMKQPVPHNLIFPHCDGVIHHGGCGTTHSVGRAEIGRAHV"
     CDS             complement(1059..2270)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Radical_SAM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg53_2"
                     /sec_met_domain="Radical_SAM (E-value: 2.7e-17, bitscore:
                     53.2, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKKRTTSSFRAMSTERKLESIFLFVTGRCNAKCAMCFYAQEMDK
                     KQPDLTFDEIKKISETAGQFNRLWISGGEPTLREDLPEILELFYKNNHIKDVNIPTNGL
                     KPDRIVEWIKRFRQNCPDCNINVSLSLDGFGTTHDTQRGVPGNFYKTLETLRKIQENFG
                     DDGKVLKNIATVITKYNIDQIEDFMTWVYGRFRTSTHTIEAARGMTRDDGVKILTESTL
                     RKIQDDISPIYSAYADRMVADTTGLRKPITRFFYLGLIRTLYNVRASNIDHPTPWGMDC
                     TAGETTLVIDYDGRFRACELREPLGNIKEYGCDISKVMNSEAMKQEIAAIGHGYKANCW
                     CTHGCWITSSVIFNPRKMIRSVYKGYRETKRLNHPLAINEQKLQTMEAKYHLDIERLRQ
                     LNIR"
     CDS             2546..2656
                     /locus_tag="ctg53_3"
                     /transl_table=11
                     /translation="MKKPRCKYTDFSIPVKGYNAKLCFTTYNKNKKAPFF"
     CDS             complement(2693..3448)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg53_4"
                     /sec_met_domain="Fer2_3 (E-value: 1.2e-26, bitscore: 82.5,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 2.5e-12, bitscore: 36.8,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.6e-06, bitscore: 17.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKDISVTLKVWRQRGPKEKGQFETYKIEKINQSVSFLEMLDILN
                     EQLVNEGKEPIVFDHDCREGICGMCSLYVNGHPHGPATGATTCQLYMRRFHDGETITIE
                     PWRSAGFPVIRDLMVDRYAYDKIIQAGGFTSVNTGGVPDANAIPIPKKDADLAMDAAAC
                     IGCGACAAACKNGSAMLFVSAKVSQLALLPQGKVEAARRAKAMVAKMDELGFGNCTNTR
                     ACEMECPKNISVSNIARLNREFICAKLQD"
     CDS             complement(3479..5422)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 194.5; E-value:
                     1.1e-59)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg53_5"
                     /sec_met_domain="FAD_binding_2 (E-value: 2e-60, bitscore:
                     194.5, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 9.2e-39,
                     bitscore: 122.0, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEINSKIPQGPLAEKWTNYKNHQKLVNPANKRRLDVIVVGTGLA
                     GASAAASLAEMGFNVLNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTIKG
                     GDYRAREANVYRLAEVSNSIIDQCVAQGVPFAREYGGLLDNRSFGGAQVSRTFYARGQT
                     GQQLLLGAYSALSRQIGLGKVKMYTRHEMLDVVKVDGRARGIIARNLITGKIERYAAHA
                     VVVATGGYVNTFFLSTNAMASNGSAAWQCYKKGAYFANPCMVQIHPTCVPVKGDFQSKL
                     TLMSESLRNDGRIWVPKKLEDAKALQAGTKKGKDIPEADRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNSTGLAVFLDFSDAINRLGKEVVKQKYGNLFDMYEEITNDNPYE
                     TPMMIYPALHYSMGGLWVDYELMTSIPGLFAIGEANFSDHGANRLGASALMQGLADGYF
                     VLPYTIQNYLSDQIQVPRFSTDLPEFVEAEKAIKDRIQKLMNVKGKETVDTIHRKLGHI
                     MWEHIGMARDAKGLQEAIQMLKDLKKEFWSNVFIPGNADNLNTELEKALRVADFIEIGT
                     LMAHDALDRAESCGGHFRTEHQTEEGEALRHDDKFMYVSCWEYQGEDKDPVMLKEDLNY
                     EFVVPQTRNYKK"
     CDS             complement(5471..6163)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg53_6"
                     /sec_met_domain="SucD_FumR (E-value: 1.1e-74, bitscore:
                     239.8, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLLNSSIGKKLIMSISGLFLVLFLLFHLSMNVAAVFSGEAYNMV
                     CSLLGSNWYAVAATLVLAAGVVIHFVYAIILTLQNRKARGNDRYAINARPKGVEWASQN
                     MFVLGLIVILFMLLHFSQFWYKMMFAELIGHHEVALGSAMVSPQDGAAFINYYFQGNAV
                     ITVLYLIWYVALWFHLTHGFWSAIQTIGWNNTIWMNRWECISKIVATVICGLFAIITII
                     FFLNGVGA"
     CDS             6286..7764
                     /locus_tag="ctg53_7"
                     /transl_table=11
                     /translation="MGEVRACVPTHGIMRKEKAFLMNNLYTFAYMRKDLNGSRHFSIGI
                     KFTILLFTIVILVLVLFSYRSDKHGNLFWQVEKLIPHHPDSALVLLEKVRDINGLSLRE
                     KARYCLLWTESRDEAGLRHTSDSIISIATDYYRTTRGCYWPPKAWFYRGKVYEDMDQPS
                     LALECYLRALEYEGENWDYEFWGRLYNQMGMLYAEQELYGKAMSFLRKASAQYQLLNDA
                     AGQDRILTEVKKYEMLRDSIGSLSARESIYQITSRYDVRPIREDLSKKELMLLQRGQER
                     YLYAFIIGIILFICFLLYRRWRNTQENALRREEALRRSIASQQQRMREEKEENERQITL
                     LEKRITKIKEEKDQELMLVSLQLEKQRLEICNESILNKESKHLLSVAILRKSEVYEKFH
                     DRDAGKIISEDWELLEVLLNKAYDDFTLRLKKLYPVISDTELKACMLTKIGVPANQITR
                     VLKYNSSVLRPRLFRKIFKKEGSTEAFVEFISNF"
     CDS             7874..9106
                     /locus_tag="ctg53_8"
                     /transl_table=11
                     /translation="MKSVKLASILFYLNSVFVVSCFVSCGSSPTEASSLLTADIRGGMD
                     KPGLLELGDEIKGVTFVPLEVTTDDASLIDGVYDYAVTDRYIYVLPVKEPRIVLFDRQG
                     RFIRTLVKEGQGPGEFSGILPCIQVDERNDRLFLFSNNRVWEYTLEGEFIGQSTHEYSV
                     IYMRHIGKDRFAAISFPFQPFNGGGFGLGLFSRKGDTIAIKNDFYSFLLPHEKSGFTTS
                     IASAYSDAQNSVLFKTGSNDTVFCISADRISAACVLDLKNSDAEVIRSLDVTDMSNLRI
                     EKKDPKDIFVQDMIEFPAHYYFRLLYNQGYYIASVDKKTGKTLVEKCEMPGSIYELADA
                     NLQHGMQGTRSYRNFPVWGRVIKDELVQVVTPYELNLYKSLHSITIPQELDLKGEEGNP
                     VFVFYSLKQPL"
     CDS             complement(9519..10349)
                     /locus_tag="ctg53_9"
                     /transl_table=11
                     /translation="MKNYLFHICLLICVFFIACEPITDRMEMGSVVAESDLRIEVYTTT
                     EGGNQVVMSNETPQVGSFWDYIVSTSVRQRDTVLLPFLGEHKITFTGLCAGGTVTTTRT
                     VKIDRIDHALAPEWALLAGTEKEGKTWVWDNEGLIWGDGGYLYDIAPMWSGLSAEDMES
                     KFPEDFAQSITFDLNGGANFTKKKANGTIVEKGSFSLDLSRSIPNGYNTAEWSTALIKI
                     NEATVMHGISPNEGNTTIHQFEVMLLDKDHLVLAYPEQGISPGGRCWYWKFKAQ"
     CDS             complement(10370..12064)
                     /locus_tag="ctg53_10"
                     /transl_table=11
                     /translation="MKKIIYLLQIVLVLLTSCDSILEVDNLTKKDTSNFPSSPKDAESA
                     LAGCYSILPYGLPSQKSFYLAELLSDDRFGGAGEGDSDTQAVNQMKKVGENMFADGWKQ
                     NYTGIFRCNTLIETIDLVNGWESEGQKKQILGEAHFLRAYFYFELCRIFGTVPLIIETD
                     PVNNPRAQADELYAQIATDLKTAIELLPASPFGSFSAPELGHATKWAAEALIARVYLFY
                     SGYYKKEVLPLNDGGSIAKQQVTDWLDDCIANSGHGLIGDFRNLWPYSNRLTTPDYKYA
                     NDNNLRWVEETGANNETIFAIKFSTLADWSTNICYSNQMNLYFGIRSQSDYANCFPFGQ
                     GWGAGPVNPDLWESWEREEPTDIRRAGSIIDSKSPDENIMINSSDGKEMELTGFWQKKY
                     IPINAKGTDGTIANYSVFMYGRKADFQLDNTQDIVIIRFADVLLMNAELKKDVSYINRV
                     RERSGLKPKATYTDETLRNERRWELAFEGLRYHDLLRWGIAGEALNRQNGIDITNSGIK
                     TKSNFGDFVKRIEETGGFMPIPQTQIDLSNGVLEQTPGWSGGNIMYK"
     CDS             complement(12075..15239)
                     /locus_tag="ctg53_11"
                     /transl_table=11
                     /translation="MEEEKGLIRKYKRQQRFVQFVFMMFVALSISMQVTAQNNRRIKGS
                     VISGTDGMPLIGVNVVQKGTTNGTVTDLDGNFELTAPENCLLEVSYIGYMNQQIKIQSG
                     KTDYQIVLKEDSQALDEVVVVGYGVQKKKLVTGATVQVKGDDIQRLNTVSALGALQSQT
                     PGVNITQTSGMPGEGFKVTIRGLGTTGSSAPLYIIDGVTGGDINNLNPADIESIDVLKD
                     AASAAIYGSRAANGVILVTTKQGRVGKATISYDGYVGFQNVYKMAPLLNAQEYSTIMNE
                     SRMNDGLPAYDFAALVPDWDKIQSGKWNGTNWLEEIRNKNALTQNHALNITGGTEQSIY
                     SAGISYTTQDGILGKPVAPKYDRYTFRLNTEHTLFKRNNLDIIKFGENLIFTYKENSGI
                     GIGNIHWNDIHSMMVASPFLPMNDENGDYHYSIPWNVYEANPVAVMEYGRGQNITKNKN
                     LRANAYLEIQPIKGLKFRSNFGLNSYTSSYRSFTPEYDLSMNTFNKENKVSQNLSTGTD
                     WTWENTLNYSFNVAKQHNIDVLVGQSVEKRGMGEEMNGSNVNSIFSDLYHAYLDNTTII
                     TPGKTTLGGSPLRKLGIVSVFGRVNYNYKETYLATIVMRADASSNFAKGNRWGYFPSVS
                     AGWVLSNEAFMESTKNWLDFLKVRASWGQNGNADIDPFQYLATISFSNSQYFFGSNKDI
                     PVSGAYPDILPNKDVTWETSEQLDLGVDARLLNGRMGISFDWYNKATKDWLVQAPILDT
                     YGANAPFVNGGDVRNRGFEIALNWNDQVGDFTYGANLNISRNKNEVTKIANTEGIIHGD
                     PYVLSNGAPEMYRAQVGYPIGYFYGYKTLGVFQNETEINAYQGAKLAGTAPGDLIFQDT
                     NGDGSITEDDRCMIGDPNPDVNLGLSLNFGYKGFDLAITANGVFGNQIAKSYRSAGDSP
                     LENYTTDIFERWHGEGTSNRLPRLTSGTHTNWQYISDIYIENGDYLRLQNITLGYDFKK
                     LFTKLPLQQARLYVTAQNLFTITGYSGMDPEVGHSGEDNSQWSSGINVGFYPAPRTYMV
                     GVNLKF"
ORIGIN
        1 tgtgtgactg gagttcagac gtgtgctctt ccgatctccg cccttcctac gctatgggtc
       61 gtgccgcaac ctccatgatg gataacgccg tcgcagtgcg ggaatatcaa attatgcgga
      121 accggctgct tcattaagaa taaatgttta tccgcttgta aggtgattcc tgtctttgcc
      181 caaccggaac cgatgatgag ccgataatca tgtttcttgc aaatatcgac caaggctttg
      241 ctgaaacggt taccatcctt ggaactacaa ctcccgaggg taaaaaagat aatagggctt
      301 tgagcgctgt cgacgaatga tatcatttcc tcgtaagcct tctcatcata ttgaaaagtg
      361 tcattgaagc aatagcctcc gatcgaccat tcgaacgtcc agtccggatc tacgtttcct
      421 aggtgctggc tgaaaagcaa gtaattatat gaacgctctc ccgcgtgata gccaaaattg
      481 cggatcggag cgagtccgta tttagcccgg ttcttattga tcgtgtcttt gaccatgaaa
      541 ttggtcatcc ggttcatcaa cttccatagg atagcgggag tgatgatcgg gttgggtttg
      601 ggaaatggca atacggccgg gggaatcttc ttacccggca agaacggggc gtaggcggta
      661 cgtatcaagg gcttcttgca atactcggcg atacttgcga cagcaaattc cgagttggtc
      721 gatactaaaa tatcatgctc ttttagtagg ggaatcaatt gatcgaactg tttatcgatc
      781 acgttcctca tccatttaag gaatggccgg aatttatgtg agttttgcgc tgcgctatcg
      841 atcatgccgc cgatatcgtc aaactgctgc aatacgtatt taaatccgta gggtttaacg
      901 gtctcctcga atatttgagg gagattgatg gtcacctcat ggccacgtct ttccaattcg
      961 gccgctatgg ccaaataagg aagaacgtcg ccttgtgagc ctctggttac taatagtatt
     1021 ttcatgctac gtttatttat gggctatgag ggtcttgttt accggatatt cagttgacgc
     1081 aaacgctcga tgtccagatg gtatttggct tccatcgttt gtagtttctg ctcattgatg
     1141 gctaggggat gattcaatcg tttcgtttcc cggtatcctt tatatacgga gcgaatcatc
     1201 ttacgtggat tgaaaatgac ggatgaggtg atccaacagc cgtgcgtaca ccaacagttg
     1261 gctttatacc catgtccgat agcggctatt tcctgtttca tcgcttcgct attcatcact
     1321 ttacttatat cgcaaccata ttcttttata tttccgagcg gttcccgtag ctcgcaggca
     1381 cgaaaacgtc cgtcgtagtc gattaccaag gtagtctctc cggccgtaca atccatcccc
     1441 caaggggtcg ggtgatctat gttgctggca cgcacattat ataaggtacg tataaggccg
     1501 agatagaaga agcgtgtgat cggtttcctt aagccggtgg tatccgctac catccgatcc
     1561 gcataagcag aatagatagg ggatatgtca tcttgtattt tgcgtagcgt tgactcggtt
     1621 aggattttca cgccatcgtc acgggtcatg cctctggcag cctcaatcgt atgcgtggag
     1681 gtacggaaac gtccgtatac ccaagtcatg aagtcttcta tctggtctat attgtatttc
     1741 gtgataacgg ttgctatatt ttttaagact ttgccgtcat ctccgaaatt ctcctgtatc
     1801 ttacgcaggg tttccagtgt cttatagaag tttcccggta cgcctctctg tgtatcgtgg
     1861 gtcgtaccga aaccatccaa ggaaaggctt acgttaatat tacaatccgg gcagttctgg
     1921 cggaaccgtt ttatccattc gacgatccgg tctggtttta agccgttcgt agggatgttc
     1981 acatctttga tatggttatt tttgtagaat aactccaata tttccggtag atcctcacgc
     2041 aaggtaggct cacccccgga tatccataat cgattgaatt gcccggcggt ttctgatatc
     2101 ttcttgattt catcgaaagt gaggtcgggt tgcttcttat ccatttcttg ggcatagaaa
     2161 cacattgcgc atttggcgtt gcatcggcct gttacgaaaa ggaagatcga ctcgagtttt
     2221 ctttccgtgc tcattgccct gaaagaactg gtggttcgtt ttttgtccat tttatttttg
     2281 ttttaccatt tgtcttatct ggcgcatgat tttttccttg tgtttgatca acacccggag
     2341 aaaataacat aagaagccaa ataaaatact tattagcata tactatatga tctttaaagg
     2401 caaagatcga cgataaaatg acgctaaaca atctctattt gcagtatttt atggtccatg
     2461 tttaaaaggt aggtctataa acaattaaag cctgtctcac gacaagccct aaccaaactt
     2521 tgttaacctt aaatctaata ctattatgaa aaaaccacga tgcaaatata cggacttttc
     2581 aattcctgtc aagggctata atgctaaatt atgttttacg acatataaca aaaacaaaaa
     2641 ggcgcctttc ttttagagaa agacgccttt tccatgatat actaatcaaa tattagtctt
     2701 gtaatttagc gcaaatgaac tcgcggttca aacgagcgat gttgctaacg gagatattct
     2761 tcggacattc catctcgcaa gcacgtgtgt tcgtacagtt accgaagcca agctcatcca
     2821 ttttagcgac catagctttg gcacggcgag cagcctcgac tttaccttga ggcaacaaag
     2881 ccagctggct aaccttagcg gatacgaata acatagcgga accattctta caagcggcag
     2941 cacaagcgcc acaaccgata caagcggcag cgtccatggc taagtctgcg tccttctttg
     3001 ggataggtat cgcattagcg tcgggtacac cacctgtgtt gacagatgtg aaaccacccg
     3061 cttggatgat tttgtcgtaa gcgtagcggt ctaccatcaa gtcgcggata acagggaaac
     3121 ctgcggaacg ccacggttcg atcgtgatcg tctctccatc gtggaaacga cgcatatata
     3181 actggcaagt cgtagctcca gttgccggtc cgtgcgggtg tccgtttaca tacaatgaac
     3241 acatgccaca gataccctcg cggcagtcgt gatcgaatac gatcggttcc ttaccctcgt
     3301 tgaccaactg ctcgttcaag atatccaaca tttccaagaa agagacactc tgattgatct
     3361 tctcaatttt gtatgtctcg aactgtcctt tctccttcgg acctctctga cgccaaacct
     3421 taagtgttac acttatatct ttatccatga ttctaatttt ttctgagatt gatgattatt
     3481 acttcttgta gttacgtgtt tgaggaacaa cgaactcata gttcaaatcc tctttcaaca
     3541 tgacaggatc tttgtcctcg ccttggtact cccagcaaga tacgtacatg aacttatcgt
     3601 catgacgcaa ggcctcacct tcttctgtct ggtgctccgt acggaagtga ccaccacaag
     3661 actcagcgcg gtccaaagca tcgtgtgcca tcaatgtacc gatctcgata aagtcggcta
     3721 cacgtaatgc tttctctaac tcggtattca agttgtctgc gttgcctggg atgaatacgt
     3781 tgctccagaa ctctttcttc aagtctttca gcatctggat agcttcttgc aaaccttttg
     3841 cgtcgcgtgc cataccgata tgttcccaca tgatatgacc tagtttgcgg tggatagtgt
     3901 ctacggtttc tttacccttg acgttcatca atttttggat acgatccttg atggcctttt
     3961 ctgcctcgac gaactccggc agatccgtgc tgaagcgagg aacttggatt tggtcggaca
     4021 aatagttctg gatcgtgtat ggtaatacga aataaccatc ggccaatccc tgcatcaaag
     4081 cggaagcacc taaacggttc gctccgtgat cggagaagtt tgcctcaccg atagcgaaca
     4141 gacccggaat ggaggtcatc aactcatagt caacccacaa tccacccatt gagtagtgca
     4201 atgccgggta gatcatcatc ggagtctcgt atggattatc gttcgtgatc tcttcgtaca
     4261 tatcgaacaa gttaccgtat ttctgcttaa cgacctcttt acccaagcga ttgatcgcgt
     4321 cggagaaatc caagaatacg gccaagcccg tgctgttcac gccgaaacct gcgtcgcaac
     4381 gctctttagc ggcacgagaa gccacgtcgc gaggaaccaa gtttccgaat gccggataac
     4441 gacgctccaa ataataatca cggtctgcct cgggaatatc tttacctttc ttcgttccgg
     4501 cctgtagagc tttagcgtct tccagtttct tcggaaccca gatacggccg tcgttacgca
     4561 aggattcgga catcaaagtc aatttagatt ggaagtcacc tttcaccggt acgcaagtcg
     4621 ggtggatctg aaccatacaa ggattagcga agtaagcgcc tttcttgtag cattgccatg
     4681 cggcggaacc gttagatgcc atagcgttgg ttgacaagaa gaacgtatta acgtaaccac
     4741 ccgtagctac aactacagcg tgagcggcgt aacgctcgat cttacctgta atcaagttgc
     4801 gggcgatgat accacgagca cgaccgtcta ccttaactac atccaacatc tcatgacgag
     4861 tgtacatctt aaccttaccc aaaccgatct gacggctcaa cgctgaataa gcgcctaaca
     4921 aaagctgctg acccgtctgg ccacgggcgt agaacgtacg cgatacctga gcgccaccga
     4981 atgaacggtt atccaacaaa ccaccatatt cgcgagcgaa aggaacgcct tgagccacgc
     5041 actggtcgat gattgagtta gaaacctcag ccaaacgata aacgttagcc tcacgagcac
     5101 ggtagtcacc acctttgatc gtatcgtaga acaaacggta aacagagtca ccatcattct
     5161 ggtagttctt agcggcgttg ataccacctt gagcggcgat agagtgcgca cggcggggag
     5221 aatcttggat acagaagttc aatacgttga atcccatctc tgccaaagat gcggcagcgg
     5281 aagctccggc caaacctgta ccgactacga taacatccaa acgacgcttg ttagcggggt
     5341 tcaccaattt ctggtgattt ttataattag tccacttctc agccaacggg ccttgaggta
     5401 ttttagaatt tatttcagac ataatgattt aatttcaaaa gttcttaatt ataaaacctg
     5461 tagcttgcaa ttaagcacct actccgttta ggaagaagat gatagtaatg atcgcgaaaa
     5521 gtccgcaaat aaccgtagct acgatcttag agatacattc ccaacggttc atccagatcg
     5581 tattattcca accaattgtt tggatagcgc tccagaaccc gtgagtcaag tggaaccaca
     5641 aagccacgta ccagatcaaa taaagaacag tgatcacggc attaccttgg aagtaatagt
     5701 tgataaaagc ggctccgtct tgtggagata ccatagctga ccccaatgca acttcgtgat
     5761 gaccgatcaa ttcggcgaac atcatcttat accagaactg gctgaagtgc aacagcatga
     5821 acaggataac aatcaaaccc aaaacgaaca tgttctgaga tgcccattcc acgcctttcg
     5881 gacgagcgtt gatagcgtaa cggtcgttac cacgtgcctt acggttttgc aaggtaagaa
     5941 tgatagcgta cacgaagtgg atcacaacgc ctgcggccaa tacgagagta gctgccacag
     6001 cgtaccaatt agagcccaac agcgaacaaa ccatgttata agcctctccg gagaaaacgg
     6061 ccgccacgtt catcgacagg tggaacaata agaacagaac aagaaagagg cctgatatac
     6121 tcattatcag cttcttcccg atagaagaat taagtaacca cataagataa taatttaagt
     6181 tatttaattg tatttagaaa tttctactta aactatgtaa ttatcacgca aaggtatgct
     6241 aaatccatat attgcgcaaa cgattaaaga aatatttctg cattaatggg agaggtcagg
     6301 gcatgtgtcc cgacacatgg aataatgcgg aaggaaaagg ctttccttat gaataattta
     6361 tatacatttg cctatatgcg taaggatttg aatgggtcac ggcatttttc catagggatc
     6421 aagtttacga tcttattatt tacgatcgtg atcttggttc ttgtgctttt ttcatatagg
     6481 agcgacaagc atggcaacct gttctggcag gtagagaaat tgattccgca tcatccggac
     6541 agtgctttgg tgttattaga gaaagtgagg gatatcaatg gattatcgct tcgagagaaa
     6601 gcccgttatt gtctgttatg gaccgaatca cgggatgagg cgggattgag gcatacatcg
     6661 gattccataa tctctatcgc tacggattat tataggacga cacgaggctg ttactggcct
     6721 cccaaagctt ggttttaccg ggggaaagtt tatgaggata tggatcaacc gtccctagct
     6781 ttggaatgct atttacgtgc gttggaatat gagggagaga attgggatta tgaattctgg
     6841 ggaaggttat ataaccaaat ggggatgctg tacgccgagc aggaattata tggcaaggct
     6901 atgtcttttt tgagaaaagc gagtgctcaa tatcagttat tgaacgatgc ggccggacaa
     6961 gaccggatac tgaccgaggt caagaaatac gagatgttac gggattctat cggatcacta
     7021 tcagcgagag aatcgattta tcagatcact tcccgctatg atgtaaggcc gatccgtgag
     7081 gacttgtcta agaaagagtt gatgctatta caaaggggac aggagcgtta tctgtacgca
     7141 tttattatcg gcataatcct atttatttgc ttcctccttt atcggcgatg gagaaatacg
     7201 caggaaaacg ctcttcgaag ggaagaagcc ttgcgacgtt cgattgctag ccagcaacaa
     7261 cgtatgcgag aagaaaaaga agagaatgaa cggcaaatca cccttttgga aaaaagaatt
     7321 acgaaaataa aggaagaaaa ggatcaagag ttgatgttgg tttccttaca attggaaaaa
     7381 caacggctgg aaatttgtaa cgagtcgatt cttaataagg agagtaagca tttattatct
     7441 gtcgcgatct tgcggaaatc ggaggtctat gagaagtttc acgatcggga tgccggcaag
     7501 attatctctg aggattggga gcttttggag gttttgttga ataaggctta tgatgacttt
     7561 accttacggc tgaaaaagct atatcctgtt atttccgata cggagttgaa ggcctgtatg
     7621 ctcacgaaaa tcggtgttcc cgccaaccag atcacacggg tattgaaata taatagttcg
     7681 gtacttcgtc ctcgtctatt ccggaagatt tttaagaaag aaggttctac ggaggcattt
     7741 gtggagttta tatcaaactt ttgattatta tatatttata gcggtcttgg caggtttgtt
     7801 ctcatttttg ttctcattta ttatgtgatt tgtgagatat acgggatatt tttggaggca
     7861 aaaaagcatg gttatgaaaa gtgtaaagtt agcctctatc ttgttttatt taaatagtgt
     7921 ttttgtcgtt tcttgtttcg tgtcatgcgg ttcttcgcca acggaagcgt catctctttt
     7981 aaccgcggat ataagagggg ggatggataa accggggcta ttggaattag gcgatgagat
     8041 caagggggtt acttttgtcc ctttagaggt gaccacggat gatgcctcgt tgatagacgg
     8101 agtttatgat tatgccgtga cagatcgata tatctatgtg cttcccgtaa aagagccccg
     8161 tatcgtcctg ttcgatcggc aagggcgttt tatccggacg ttggtaaaag aagggcaggg
     8221 gccgggtgaa tttagcggta ttctgccatg tatccaagtg gacgaacgta atgatcgcct
     8281 ttttttattt agtaataatc gagtttggga atatacgtta gaaggtgaat ttatcggaca
     8341 atccacccat gagtattcgg taatctatat gcgtcatatc ggaaaggatc gtttcgccgc
     8401 catatcattc ccttttcagc ctttcaacgg agggggattc ggattgggcc tattttcgag
     8461 gaaaggggat acgatagcga tcaagaatga tttttattcc tttttattac cccatgagaa
     8521 gagcgggttc acgacaagta tcgcctccgc ttattctgat gcgcaaaact ccgtgttgtt
     8581 taagaccggt agtaatgata cggtcttctg tatctcggcg gatcgaataa gtgcggcttg
     8641 tgtccttgat ctgaaaaact cggatgcgga agtgattcgt tcgttggatg ttacggacat
     8701 gagtaatttg cgaattgaaa aaaaagaccc caaggatatc tttgtgcaag atatgattga
     8761 gtttccggca cattattatt tccgtttatt gtataaccaa ggctattata tcgcctctgt
     8821 ggataaaaag acgggaaaga cactcgtgga aaaatgcgag atgccggggt ctatctatga
     8881 actggcggac gcgaaccttc aacatggcat gcagggtacg agaagttatc ggaatttccc
     8941 ggtctggggg agggtcataa aagatgagtt ggtacaagta gtgaccccgt atgagctaaa
     9001 cttatataag tcgcttcact cgatcacgat tccgcaggag ttggacttaa aaggagagga
     9061 gggcaatccg gtttttgtgt tctattcgtt aaaacaacct ttatagtttg ttaatccaca
     9121 tggcgccatc ctgtttattg tatatttctt aaaaacggat tccatagtag tcaactttac
     9181 tatccataga aagtatgatt agtattaata gtaatgcaga atactatgga tgctaattga
     9241 ctcccataca gatatatttt tattatatgc tgattatctg aaatataaat aataatcttt
     9301 acatattaga cttattgttt tttttaagag attaaattta atgcgattgc ccatggttta
     9361 tggttatgaa acaaagtgtt ctcaaagtcg aaacaggatg tttatgggta tggaacaacg
     9421 ggaatgtcta aagaggaaat ctttggcaat tgtaataggt tgataatgtg tatatgaaaa
     9481 agagatgagg aacaaatatc cctcatctct tttttaattc attgagcttt gaacttccaa
     9541 taccagcaac ggccaccagg gctgatgccc tgttccggat atgccagaac gaggtggtct
     9601 ttatctaaga gcataacttc gaattgatgt atggttgtgt tcccttcatt gggagatatg
     9661 ccatgcatga cagtcgcctc attgatcttg attaaagccg tagaccattc cgccgtgtta
     9721 tacccgttag gtatgcttcg gctgagatct aggctgaaac ttcctttttc tacgatggta
     9781 ccgttggctt ttttcttggt gaaattagct cctccattta gatcaaacgt gatactttgg
     9841 gcgaaatctt ccggaaattt actttccata tcctctgcgg agaggccgga ccacatggga
     9901 gcgatgtcgt ataagtaacc gccatctccc catataagcc cttcgttgtc ccaaacccat
     9961 gttttacctt ctttctccgt tcccgctaaa agcgcccatt ccggtgcgag cgcatgatcg
    10021 attctgtcga tctttacggt acgtgtagtc gttacggttc ctccggcgca aagtcccgtg
    10081 aaggtgattt tgtgttctcc aaggaaagga agtaatacgg tatccctttg ccggacagaa
    10141 gtacttacga tataatccca aaagcttccc acttgcgggg tctcgttaga cattacgact
    10201 tgattacctc cctctgttgt cgtgtatacc tcgattctca ggtcactttc cgctactacc
    10261 gaacccattt ccatacgatc ggttatgggt tcacatgcga tgaaaaatac gcatattagc
    10321 aggcatatat gaaataaata gtttttcatg ttcaattgat tttaatggtt tatttataca
    10381 taatgtttcc tccggaccac ccgggtgttt gctccaatac cccgttggat aaatcgattt
    10441 gagtctgagg aataggcatg aatcctccgg tttcctctat acgtttgacg aaatcgccga
    10501 agttactttt tgtcttgatg ccactattcg tgatatcgat accgttttgc ctgttcaagg
    10561 cttcgccggc tatgccccaa cggaggagat catgataacg caagccctca aaggcgagtt
    10621 cccatcgtcg ttcgttccgt agtgtctcgt ccgtgtaagt ggctttaggc tttagacctg
    10681 agcgctcacg tacccgattt atataagaga catctttctt taactcagca ttcatcaata
    10741 agacatcggc gaaacggatt atcacgatat cttgtgtatt atcaagttgg aaatccgcct
    10801 ttcgtccgta catgaatacg ctatagttgg cgatagtgcc gtctgtgcct ttggcgttga
    10861 tcggtatgta tttcttttgc cagaaaccgg tcaattccat ctctttccca tcgctgctgt
    10921 ttatcatgat attttcatcc ggactttttg agtctatgat agagccggca cgacgtatat
    10981 ctgtcggttc ctctctttcc catgattccc atagatcggg gtttacggga cctgctcccc
    11041 agccttgtcc gaatgggaaa caattcgcat aatcgctttg ggaacggatt ccgaaatata
    11101 ggttcatctg gtttgagtag cagatgtttg tactccagtc cgctaaagtt gagaacttga
    11161 ttgcgaatat agtctcgtta ttagcgccgg tttcctctac ccatcgtaag ttattatcgt
    11221 tagcgtattt atagtccgga gttgtaagtc tgttgctata aggccataaa ttacggaaat
    11281 caccgatcaa gccgtgtccg ctatttgcga tacaatcatc cagccaatct gtcacttgtt
    11341 gttttgcgat acttcccccg tcatttaaag gcaacacctc tttcttataa tacccgctat
    11401 agaataaata tactctggct atcaatgctt ctgcggccca tttggtggca tgccctaatt
    11461 ccggagcgga gaaagagccg aacggagagg cggggagaag ttcgatggcc gtttttaaat
    11521 cagtggctat ctgtgcgtaa agctcatctg cttgcgctct aggattattt acagggtctg
    11581 tttctatgat caagggaacc gtaccgaata tacgacataa ttcgaaatag aaataagcgc
    11641 gtaggaagtg agcctctcct aagatttgtt tcttctgccc ttcagattcc cacccgttta
    11701 caagatctat cgtttcgatt agcgtgttac aacggaatat tccggtgtaa ttctgtttcc
    11761 atccgtcggc aaacatgttc tctcccactt ttttcatctg gttgacagct tgcgtgtcac
    11821 tatcaccttc tccggcacct ccgaaacgat cgtcagaaag taattccgcc agatagaaag
    11881 acttctgcga gggtaatccg taaggcaata tcgaataaca accggctaat gcggactcgg
    11941 cgtctttggg cgaacttgga aagtttgagg tatctttttt agtcagattg tcgacttcca
    12001 aaatactgtc gcaacttgtt aataaaacaa ggactatctg aagtaaataa ataatctttt
    12061 tcatatcttt tttcttagaa ttttagatta acaccaacca tatatgtacg aggagcggga
    12121 tagaatccta cattgatacc ggaagaccac tggctattat cctctccgga atgtcctact
    12181 tcgggatcca ttcctgagta tccggtgatc gtgaacaaat tctgggccgt tacatacaaa
    12241 cgagcctgtt ggagaggcaa cttggtaaat agctttttga aatcataccc tagggtgata
    12301 ttttgcaagc gaagatagtc accattctct atatagatat cggagatata ttgccagttc
    12361 gtatgcgtac cggaggttag gcgaggaagt ctgttagatg ttccttctcc atgccaacgt
    12421 tcaaaaatat cggtcgtata gttttccaaa gggctgtctc cggcggaacg gtatgatttg
    12481 gcgatctggt tgccaaatac cccgttggcg gtgatggcca gatcaaatcc tttgtaaccg
    12541 aaattcaagg aaagacctag gttaacatcc gggttcgggt ctccgatcat gcaacggtcg
    12601 tcttctgtga tgcttccatc tccgttcgtg tcttggaata tcaagtcgcc gggtgctgtt
    12661 cccgctagtt tagcgccttg ataagcattg atttccgtct cgttctggaa tacgcccaat
    12721 gtcttatatc cgtagaagta accgattgga tatccaactt gtgccctgta catttcggga
    12781 gctccgttgc tcaatacata aggatctcca tgaatgatac cttccgtgtt agcgattttt
    12841 gtaacctcat tcttgtttct tgaaatattc aagttcgctc cataggtgaa atctcctact
    12901 tggtcgttcc agtttaatgc gatctcaaaa cctctgttgc gtacgtcacc tccgttcacg
    12961 aagggggcat tggctccata agtatccaag ataggggctt gaaccaacca atccttggtc
    13021 gctttgttat accagtcgaa agagattccc atccggccat tgagcaagcg ggcatctacg
    13081 ccaaggtcta attgctcgga ggtttcccat gtaacgtcct tattcggcaa gatatccggg
    13141 tatgctccgg atacgggaat atccttgttt gagccgaaga aatattggga attactgaaa
    13201 gagatggtcg ctagatattg gaacggatcg atatctgcgt taccattttg tccccagctt
    13261 gcacgtactt tcaagaagtc tagccaattc ttggtggatt ccatgaatgc ctcattggat
    13321 agtacccaac ccgccgatac ggaagggaaa tatccccatc ggtttccttt ggcgaagttg
    13381 gaggatgcgt ctgctcgcat aacgattgtg gccaaataag tttccttata attatagttg
    13441 acacggccaa atacggatac aatgcccaat ttccttaaag gagatccgcc taacgtggtc
    13501 ttacctggtg ttatgatggt cgtattatcc aaataggcgt gatacagatc ggagaagatc
    13561 gagtttacat ttgagccatt catctcttct cccatgcctc ttttttctac ggattgtccg
    13621 actaagacat cgatattgtg ttgtttcgct acgttgaacg agtagttcaa cgtgttttcc
    13681 caagtccaat cggtacccgt ggaaaggttt tgactgactt tgttctcttt gttgaacgta
    13741 ttcattgaca aatcatactc aggcgtaaat gagcggtatg aacttgtata gctattcaaa
    13801 ccgaaattac ttctgaactt aagtccttta atcggttgta tctccaagta agcgttcgca
    13861 cgtaagttct tgttctttgt gatgttctgt cctctcccat attccatgac tgctaccgga
    13921 tttgcctcat atacattcca ggggattgag taatgataat ctccgttttc gtcattcatt
    13981 ggaaggaatg ggcttgcgac catcatacta tggatatcat tccagtgtat attgccgatt
    14041 ccgattccgg aattctcttt atacgtgaaa atcaggtttt ccccgaattt gataatatcc
    14101 aaattattgc gtttgaataa cgtatgttcc gtattcaggc ggaatgtata acgatcgtat
    14161 ttgggagcta ccggttttcc taagataccg tcttgggtcg tataggaaat acccgcagag
    14221 taaatagatt gctctgtgcc accggtgata tttagggcat ggttttgtgt caacgcattt
    14281 ttattgcgta tctcttccag ccaatttgtc ccgttccatt tcccactttg gatcttgtcc
    14341 caatcgggta ctaatgcggc gaagtcataa gcgggtaagc cgtcattcat gcgagactcg
    14401 ttcataatgg tcgagtattc ttgggcgttt aataacggag ccattttata tacattttgg
    14461 aatcctacat atccgtcgta tgagatcgtg gcttttccta cccgtccttg cttagttgtg
    14521 actaagataa ccccattagc ggcacgagaa ccatagattg cggcggaagc ggcatctttt
    14581 aaaacgtcga tggattcgat atccgcaggg ttcaagttat tgatatctcc accagtaact
    14641 ccatcgatga tatataatgg agcagatgaa ccagtggtac ctaaacctct gattgtgact
    14701 ttgaatcctt cacccggcat accggacgtt tgtgtaatgt tcacacctgg agtctgactc
    14761 tgtaaggcac ctaaggcgct taccgtgttt aaccgttgga tatcgtctcc ttttacttgt
    14821 acggtggcgc cggtgactaa ctttttcttt tgtacgccat atcctaccac taccacctca
    14881 tccaatgctt gggagtcttc tttcaatacg atctgataat cagtctttcc ggactgtatc
    14941 ttaatttgct ggttcatgta tccgatatag gatacttcca gtaaacaatt ttccggggct
    15001 gtcaactcga aattaccgtc cagatcggtt accgttccat tggttgttcc tttctgcact
    15061 acgtttacac caattaaagg cataccgtct gttcctgata taacagagcc tttaattctc
    15121 ctattgtttt gtgctgtgac ttgcatgctt attgaaagcg ctacaaacat catgaacacg
    15181 aattgtacaa accgctgttg tcgtttgtac ttacgaatca aacctttttc ttcttccata
    15241 agaattagtt gtttatagat taacatgaat aataatacgt gaatatcccc ttataacacc
    15301 attttgtaat gatgctaaat aattgtgtac cttatatgtc gtttaaaatc agaaagccat
    15361 gattacattg tttatagtag gtgcggaagc tgggtaattt at
//
