LOCUS       c00104_gnlPro..        12940 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DMBGJHNH_104.
ACCESSION   c00104_gnlPro..
VERSION     c00104_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 22:26:31
            Original ID  :: gnl|Prokka|DMBGJHNH_104
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12940
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12940
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[6742:12728]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      6743..12728
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..12940
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..12940
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(582..686)
                     /locus_tag="ctg104_1"
                     /transl_table=11
                     /translation="MNIMSVNGLWRKQTYFLFVHSRKGKHTFINITDI"
     CDS             complement(1355..2944)
                     /locus_tag="ctg104_2"
                     /transl_table=11
                     /translation="MKRFINISFLSLVFAGMALTGCNDDLTTSSYVKVNDEDVLGNVSQ
                     LEKVLTSAYKQLYFNTDKGDRVYAGLPGFQMYVDASGADVISHTNMGGDQVTAYQYSNS
                     KTQADGNASKIWSMCYNVINRANIILTNVDAAAGDETQKKHIKGQALAMRGIQYFHLIQ
                     NYQQTYAIAKSKRGVILRTSSDDESHKGFSTVEEVYTQIVSDLTTAKTLLADYNPDDMW
                     LINSKICSGILARVYLVMQNWDGAYNEAKIVYDQHSQLMTREQYRSGFDDMISGNYAEV
                     VWAMKYTADNNLGGSTQFNFWYNQDASYGEGYADGPIYSFLDYFVDEQFVKLFEEKEDR
                     YQFWKRTNNANTEINTKWAFDKYKHYGEDGGSVIQSATRPEVCLMRGAEMLLIMAEAAA
                     QKGNSGEALNLLNRLQVARNATPTTNAGGEALLEDIYVERRKELICEGQAGFYDLVRLQ
                     KRLVRIGESTTNPAGHYVWGMQYLNGYNALDPQPIGTLESNDYRFFCQIPQMEILNNDA
                     ISESDQNPWSGQ"
     CDS             complement(2963..6241)
                     /locus_tag="ctg104_3"
                     /transl_table=11
                     /translation="MISVLLGAAGAIAANPTGPETMVVQQGNKVTGLVEDQMGPVAGAS
                     VVVKGTTIGTITDIDGKFTLDNVRRGAVIVISFVGLATQEITWNGQSILNVKLSDATQD
                     LDEVVVVAYGTAKKSTFTGSASVVKAEKLEKIMGSGFAEALQGMSAGVNVVNVQGNPGA
                     DARVEIRGIASMSGKADPLYIVDGMPYDGKLNQINPTDIESMTVLKDAAATSLYGSRAA
                     NGVVMITTKRGKSEKPRINFRGGWGTSDNAVKNPKKADPYQQLENTWYALYYDALLYDG
                     MNMQQAGDYASSQALTKQVKATKDSNGNLIYVTPFRHINENYVLHDGNGNPYMNPNLEY
                     VWDEDDWDVYKAIFSRKLRQDYSVDISGQANGGKTAYFFSGGYLDDQGYGNRQYYKRYS
                     FRTNLSTELFDWWKVAGSLSYSRHRQNLSGGASRAANFTTTLSSPWLRNEDNTGWVVSE
                     KTGERMYSYGKYTNNFFGAHILNNSGDYWDNPNDDSFDNNMGHILSAQVNTEFTLPFNL
                     KFRSALNIDDYWYRTMQYTSAVHGSGQTAPYGISILADGGYASRYNFNKRSTTWNNVLS
                     GEWMIGDHTISGLVGHEWYTWDSHYEQGWGEGIMELGKYELSNTTKNFGVSGGRDKYSL
                     LSFFGKVDYNFLNKYYLSASLREDGSSRFSSDHRWGTFWSTGGSWRISKEGFMEDLKWI
                     DNLSLRGSYGTTGNDKLIVRESNGKAGDEVLYGYQGTYESDDLYLKSGLKPSTYPTPDL
                     KWESNQQWNIGLDFSVFNRLSGTVEYYSRTSHDLLYYKELPLSAQVGSASGYNMNIGDL
                     RNSGIEITLNANILTTKDFRWDIDANMSTLKNEVTYLPTGPYTYSGTACTYKMEEGKSL
                     YEFIAPQYDGVNPETGVPGWLIRDGNGGWKRTEKQEEVTTDDFVYCGSAIPKVFGAITN
                     NFQFKGIDLSFMFYYSYGSKISDYTYKERIMNRPGVGVIQELVEDRWRQPGDADVLIPR
                     WSYNQYGATVKYADNFVFDNHYWRLRNLTLGYTLPKSLTRKALVENLRVYVTGNNLLTF
                     GPAKKRYTDPETGIMGNSYNGNAETDNGIQGSRRLYMVGIQITL"
     CDS             complement(6743..7789)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg104_4"
                     /sec_met_domain="IlvN (E-value: 9.8e-49, bitscore: 154.2,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 2.2e-44, bitscore: 140.3,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVMNFGGVDENVVTREEFPLEKAREVLKDETIAVIGYGVQGPGQ
                     SLNLRDNGFNVIVGQRKGGKTWEKAVADGWVPGETLFDIEEACEKATIIQYLLSDAAQI
                     EVWPRIKKYLTPGKALYFSHGFGITYKERTNIIPPADVDVILVAPKGSGTSLRRMFLQG
                     RGLNSSYAIFQDATGKAWDRVIALGIGVGSGYLFETTFKKEVYSDLTGERGTLMGAIQG
                     LLLAQYETLRENGHEPSEAFNETVEELTQSLMPLFAENGMDWMYANCSTTAQRGALDWM
                     GPFHDATKPVFQKLYSEVACGNEAQRSIDTNSKPDYREGLEKELAALRESEMWRAGAVV
                     RKLRPENN"
     CDS             complement(7831..8562)
                     /locus_tag="ctg104_5"
                     /transl_table=11
                     /translation="MEKNKVGEFHFVTESYLTDFRGRITIPMIGTYLLHAASCHAADRG
                     FGYNDMTERHTAWVLSRLAIEMTSYPAMSESVTLYTWVDEVGKLFTSRCFELVNGEGKT
                     FGFARSIWAAIDMETRRPTLLDVEGLSAYITDRPCPIEKPGKIAPVENNTSGEPYRVKY
                     SDLDVNGHLNSIKYMEHLLDLFDISLFREKEISRFEIAYQSEGKYGMELTLHNQEVSLD
                     KYNMAICNDGKAISRAAVTWI"
     CDS             complement(8599..9153)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg104_6"
                     /sec_met_domain="ALS_ss_C (E-value: 9e-19, bitscore: 56.7,
                     seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTKQLYTVIIFSENTVGLLNQITVIFTRRQLNIETLSVSPSAIK
                     GIHKFTITTFADEDTIDKVVKQIDKRVDILKAYYNTDEDLVYQEIALYKLSTELFIKMG
                     TVEDLIRKYNARILEMNEDCVVLEKSGHYDETQALFKELSETIGVLQFIRSGRVAITKS
                     KVERLSDMLSAMEKKLQEKHV"
     CDS             complement(9166..10866)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg104_7"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.7e-51, bitscore:
                     162.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKQKITGSEALLKALIAEGVDTIFGYPGGQAIPIYDSLYDYRDQ
                     LKHILVRHEQGATHAAQGYARVSGKVGVTVVTSGPGATNTITGIADALMDSTPMVVIAG
                     QVPSPLLGTDAFQEVDVIGITQPITKWAYQIRRPEEIAWAVSRAFYIASTGRPGPVVLD
                     LAKDAQVGLVDYEYQKVDYVRSYQPEPDIREERIEAAASLINNAKKPFCLVGQGVILGG
                     AEEELKEFLLKNDIPAGSTVLGLSALPSDFPLNKGMLGMHGNVGPNRKTNECDVLIAIG
                     MRFDDRVTGDLKTYAKQAKIIHLDIDNSEIGKNVPVDVKVLGNAKHTIPMITALLEERK
                     RPEWNAEFEPDEKEEYNKVIEKELYPTEGQLKMGEVVRKVSEATDNDAILVTDVGQNQM
                     MGVRYFKYKQTRSVVTSGGLGTMGFGLPAAIGAKLGAPDRTVCFFTGDGGIQMTIQELG
                     TIMQENLNVKIIVLNNNFLGMVRQWQELFFNERYSNTIMKNPDFVAIAKAFGIASRAVD
                     KREDLDEAIAEMLNHDGAYMLVANVETCGMVYPMVPAGGSVTNMILGDK"
     CDS             complement(10893..12728)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg104_8"
                     /sec_met_domain="ILVD_EDD (E-value: 2.1e-218, bitscore:
                     715.1, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMKNPLRSSYSTEGRRMAGARALWRANGMKEEQFGKPIIAIVNSF
                     TQFVPGHVHLHEIGQQVKAEIEKLGCFAAEFNTIAIDDGIAMGHDGMLYSLPSRDIIAD
                     SVEYMVNAHKADAMVCISNCDKITPGMLMASMRLNIPTIFVSGGPMEAGNLDGRALDLI
                     DAMIEAADDSISDEQVEKVERSACPTCGCCSGMFTANSMNCLNEAIGLALPGNGTVVAT
                     HANRTRLFKKAAKMIVDNAFKYYRDGDDSVLPRSIATRQAFLNAMSLDIAMGGSTNTVL
                     HLLAVAHEAEVDFTMKDIDMLSRKTPVICKVAPSCSYHVEDVNRAGGIIGIMNELVKAG
                     LVDGSVKRADGLTLNEAIDQYCITSVNVTEEAINIYKSAPAHRFNLVLGSQESYYKELD
                     TDRATGCIRDVEHAYVKDGGLAVLYGNIAQDGCVVKTAGVDESIFRFAGPAKVFDSQDA
                     ACEGILKDQVVSGDVVVITYEGPKGGPGMQEMLYPTSYIKSKHLGKECALITDGRFSGG
                     TSGLSIGHISPEAAAGGAIGLVKDGDIIEINIPERTIHVKVTDEELAKRREAEEARGTK
                     AFTPPFRQRTVSKALKAYAKMVASADKGGVRIVED"
ORIGIN
        1 tcgggcacgg gaacgggata gttcaaatat ttctatattg aaacatcctt ttgctgcggt
       61 tgccttgttt actattgatg atttactttt tgggatataa aagccaagtc ctatccggag
      121 aacatactat tggatacaaa gcgtcaggag agttcctgga agttaaagga ttgtcaaaat
      181 gatattttat gtatgtgctg aaggaattgt acgggcaaag ggaaatgtcg atctgttttt
      241 atagaaatct cgccgactta cctttgttcg ctttgacctg attgttgcaa tattcatatc
      301 acaaaaaatg tatattatct atgattgtta cccatatacc acatctattc ataatttatt
      361 aacatattgc tattttacac acacatcaaa aagcggttgc tctggaaata aaaactgtct
      421 aaaaacatat gattttcttt tttaaaagca ctaattgagg tgtttttctt ctctaaacga
      481 ataaaaactc cactacaata gaaatttatc tcagtttaaa cgaaattgaa atctgtttaa
      541 actaaaattt tcttcggttt aaacgagata aaaagtcgat atcagatatc tgttatgtta
      601 ataaatgtat gcttcccttt tctagaatga acaaataaaa aataagtctg tttcctccaa
      661 aggccattta cactcataat attcatatat cattcatttt tatatcattt tgattttgcc
      721 gtctgtttgg ttacaggaag tgaagtttcc atacgacact gatttgcatc aaccgtttca
      781 ctgatatcat gtccactatt atcggttgaa agagaaacta tttttcgcaa tgacatacgt
      841 ttactggtaa ttctggatca ggtgaaaata ctggattcca cgcatcgcca gcgcctgacc
      901 tttgatgtgt tttttctgtg gtacaaatat tatcaggcaa ctctttccga tatttattat
      961 gagagataaa ccggatttat tttctactaa ccctttcgac atacgaaaaa agaagtaatc
     1021 tggagccgga agtaatcgaa aagattgcca aagcattaga tatacccgaa gaagcaatta
     1081 cggaactagg cgaagccact tccattaata tcttttccgg cacctggcaa gataatgcta
     1141 attgccagaa ttataatcct acatttaacc ccttagaaaa agtcgttgaa ttatacgaac
     1201 gtttattgaa agcggagcag gagaaggtgg ccatgttaca ggaagtgcta aaggacaaaa
     1261 agtaaaacag tgaacatcaa atgttacaaa taaaagagag ggaggcatgt aataaacacc
     1321 tccctctctt ttatttattt acaacagatg aaacttactg cccgctccac ggattctgat
     1381 ctgattcgga gatcgcatca ttattcagga tttccatttg cgggatttgg cagaagaaac
     1441 ggtaatcgtt cgactccagc gtccctatcg gttgcggatc gagcgcatta tatccgttca
     1501 gatactgcat gccccatacg taatgtccgg caggattggt agttgattca ccgatacgaa
     1561 ccaatctctt ttgcaggcgc accaggtcat aaaaaccggc ttgtccttca cagatcaact
     1621 ctttacggcg ttccacatag atgtcttcca gcaaagcttc gcctccggca ttggttgtcg
     1681 gggtagcatt acgcgccacc tgcaaacggt tcagcagatt cagagcctcg ccggagttac
     1741 ccttttgggc agcagcctcc gccataatca gcagcatttc ggctccgcgc atcaggcaga
     1801 cttccggacg ggtggcgctt tgaataacgc ttccgccgtc ttcaccataa tgcttgtatt
     1861 tgtcgaaagc ccattttgta ttgatttccg tattcgcatt gttcgtacgt ttccagaact
     1921 ggtaacggtc ttctttttct tcaaatagtt tcacaaactg ctcatccacg aagtagtcaa
     1981 ggaacgagta gataggacca tcggcataac cctcgccgta gctggcatcc tggttatacc
     2041 agaaattgaa ctgcgtacta ccgcccaggt tattatcggc ggtatatttc atggcccata
     2101 ccacttccgc ataattgccg gagatcatat cgtcgaaacc ggaacggtat tgttcgcggg
     2161 tcatcaactg gctgtgctgg tcgtagacga tcttggcttc attgtaagcg ccgtcccagt
     2221 tctgcatcac cagataaaca cgggccagga ttcccgaaca tattttggag ttgatcagcc
     2281 acatatcgtc cggattataa tcggcaagca atgttttagc cgtcgtcagg tcggacacaa
     2341 tctgggtata gacttcctct acagtagaaa aacctttatg ggattcatca tcggaagagg
     2401 tacgcaggat caccccacgc ttgcttttag ctatcgcata cgtctgctgg taattctgga
     2461 tcagatggaa atactggatt ccacgcatcg ccaacgcctg gcctttgata tgttttttct
     2521 gtgtttcatc accggcggcg gcatccacat tggtcaggat gatattggca cggttgatca
     2581 cattatagca catcgaccag atttttgagg catttccgtc agcctgtgtt tttgagttgg
     2641 aatactggta tgctgttacc tgatcacctc ccatattggt atggctgatc acgtcggcac
     2701 cactcgcatc gacatacatc tggaatccgg gaagaccggc atacacacgg tctcctttat
     2761 cagtattaaa atacagctgc ttataggctg aagtcaatac tttttccaac tgggagacat
     2821 tccccagtac atcttcatcg tttactttca cgtaggagct ggttgtcagg tcgtcgttac
     2881 atccggtcag ggccatacca gcaaaaacca gggacaggaa ggatatattt ataaatcgtt
     2941 tcataaatat cattttttac gtttacaatg tgatttgaat accgaccata tacagtcttc
     3001 tcgaaccctg aataccgtta tcggtttcag cattaccgtt ataactgtta cccattatac
     3061 ctgtttcggg gtctgtgtag cgttttttgg caggaccgaa agtcaacagg ttattaccgg
     3121 ttacataaac acgcaggttt tctaccaggg ccttgcgggt aaggctctta ggcagcgtat
     3181 agcctaatgt caggtttctc agacgccagt agtggttgtc gaatacgaag ttatctgcat
     3241 attttaccgt cgcgccatac tggttgtacg accaacgtgg gataagcaca tccgcatcgc
     3301 ccggctgacg ccatctgtcc tcaaccaact cctgtatcac accgacaccc ggacggttca
     3361 tgatacgttc tttatatgta tagtccgata ttttggaacc ataagaataa tagaacatga
     3421 acgacaggtc gatccctttg aactggaagt tattggtgat agcaccgaac actttgggaa
     3481 tcgcggagcc acagtacaca aaatcgtctg tcgttacttc ttcctgcttt tccgtacgtt
     3541 tccaaccgcc gttaccatcg cggatcaacc agccgggtac tccggtttcc ggattaacac
     3601 cgtcgtactg gggagcgata aattcataca gagacttgcc ttcctccatc ttgtaggtac
     3661 aggcggtacc agaataagtg taaggacctg taggcaaata agtcacctca tttttcagcg
     3721 tactcatgtt ggcatcgata tcccatctga aatctttcgt tgtaaggata ttcgcattca
     3781 atgtgatttc aatcccgcta ttacgcaggt caccgatatt catattatac ccggatgcac
     3841 taccaacctg ggcagagaga ggcagttcct tataatacaa caagtcatgg gaagtacggg
     3901 aataatattc cactgtaccg ctaagtcggt tgaatacgga aaaatctaaa ccgatattcc
     3961 attgctgatt actttcccac ttcaagtccg gtgtcggata ggtagatggt tttaaaccgg
     4021 atttcagata caggtcatca ctttcataag taccctggta tccgtaaagg acttcatccc
     4081 ctgccttacc attcgattca cgcacgatca gcttatcatt accagtcgta ccgtaactac
     4141 cacgcaacga aaggttatca atccatttca ggtcttccat aaaaccttct ttcgatattc
     4201 gccatgaacc gcctgtcgac cagaatgtac cccagcgatg atcggagctg aaacgggaag
     4261 aaccatcctc acgaagtgaa gcggacaagt aatacttatt caagaagtta taatcgacct
     4321 taccaaagaa cgaaagcaga gagtatttat cacgtccgcc ggaaacaccg aagttcttgg
     4381 tggtattcga taattcatat ttacccagtt ccatgatacc ttcaccccaa ccttgttcgt
     4441 agtgggagtc ccaggtatac cactcatgtc cgaccagacc tgaaatcgta tggtcaccaa
     4501 tcatccattc accagacaat acattattcc aggtggtgga acgtttattg aaattataac
     4561 ggctggcata accaccgtct gccagtatag aaataccata aggtgcagtc tgtccgctgc
     4621 catgtacggc ggaagtatat tgcatggtac gataccagta atcgtcaata ttcaaagccg
     4681 aacggaattt caggttgaaa ggaagagtaa actctgtatt tacctgagca gacaggatat
     4741 gccccatatt gttatcgaaa ctgtcatcgt tcggattatc ccaataatca cccgagttat
     4801 tcaggatatg ggcaccaaag aagttattgg tatatttacc gtaactgtac atccgttccc
     4861 ctgttttttc agaaacgacc caaccggtat tatcttcatt acgtaaccag ggtgaagaca
     4921 aagtcgtcgt aaagttagcc gcacggctgg caccaccgga aaggttctgg cgatgacgcg
     4981 aataagaaag gctaccggcc actttccacc aatcgaacaa ctctgtactc aggttggtac
     5041 ggaaagaata acgtttataa tactgccggt taccatatcc ctggtcgtcc agataaccgc
     5101 cggagaagaa ataggctgtt tttccaccat tggcctgacc acttatatcc acactataat
     5161 cctggcgcag tttacgggag aagatagctt tgtagacatc ccaatcatct tcatcccaga
     5221 catattccag attaggattc atgtaaggat tcccattgcc gtcatgcaat acgtaatttt
     5281 cattgatatg tctgaacgga gtgacataaa tcagattacc attcgaatct tttgtagcct
     5341 ttacctgttt ggtcaatgcc tgcgacgaag cataatcgcc cgcctgttgc atattcatgc
     5401 cgtcataaag aagggcatca taatacaagg cataccaggt attttccagc tgctggtacg
     5461 gatcggcttt tttcggattc ttgacagcat tatccgaagt accccaacct ccgcggaagt
     5521 taatacgcgg tttttctgat ttaccccgct tggttgtaat cattacgacg ccgtttgctg
     5581 cacgcgaacc gtagagcgaa gtggccgccg catccttcag caccgtcatc gattctatgt
     5641 ccgtaggatt gatctgattc agttttccat cgtaaggcat cccgtccaca atatataacg
     5701 gatcggcctt tccggacatg gaagcaatac cacggatctc cacacgggca tcagctccgg
     5761 ggttaccctg tacattcaca acattcacac cggcactcat cccctgcaat gcttccgcaa
     5821 agccggagcc catgatcttt tcgagttttt cagcttttac aacggaggcc gatccggtga
     5881 aggttgattt cttagccgtt ccataggcta cgacaacgac ttcatccagg tcctgtgtcg
     5941 catcacttaa ttttacattt aaaatagatt gtccgttcca agtgatctcc tgagtggcca
     6001 ggccgacaaa ggaaataaca ataaccgctc cccgccgaac attatccagc gtaaactttc
     6061 catcgatatc ggttatcgta ccgatagtgg ttcctttcac tacaacagaa gctccggcga
     6121 caggtcccat ctggtcctct accaggccgg ttaccttatt accctgttgt actaccatcg
     6181 tttccggacc tgtaggattg gcagcaatcg cacctgccgc acctaataat acagaaatca
     6241 ttagtgatct aattagtttt gagttggtcc acatagctaa attcaagtct ttaattaaat
     6301 aaaattaatc acaatagcgt tcatttcatt agaggttaca cttttctaag ataaaagtga
     6361 ctggcataca tttcaataaa ataaagttaa ctaaaacaaa gatatactga tcattacaca
     6421 caacatcctt ctatatttcc actctacaaa ctacagtatc tccatcagca aatataactt
     6481 atcattattt aatacaagca taattatgta tatttattgc tctaataaat atattttaac
     6541 caccatttaa ttgatttttt tatctaaaat ccacattcaa acaatgacat acatattggg
     6601 atgaaaaatc aataacagtt gcaatcaaaa acatttttta accattaacg cattacataa
     6661 accataaaaa aacggcaacc cgaaaagccg gattgccgtt tttatatcac aaaatgttta
     6721 actattaatg tatcaccatt tattagttgt tttcaggacg aagtttacga acaacagcac
     6781 ctgcacgcca catttcactt tcgcgaagag cagccagttc tttttccaga ccttcacgat
     6841 agtcaggctt gctgtttgtg tcgatagaac gctgtgcttc gttaccgcag gcaacttcgc
     6901 tatacaactt ctggaacacc ggttttgtag catcgtggaa cgggcccatc cagtccaaag
     6961 caccacgctg tgcagttgtt gaacagtttg catacatcca gtccataccg ttttctgcga
     7021 acaacggcat caatgactga gtcagttctt ctactgtttc attgaatgct tcagaaggtt
     7081 cgtgaccgtt ttcacgcaaa gtttcgtact gagccaacag taatccctgg atagctccca
     7141 tcaaagtacc acgttcgccg gtcaggtcag aataaacttc tttcttgaat gttgtttcaa
     7201 acaagtaacc agaaccaaca ccgataccca gtgcaatcac gcgatcccat gctttgcctg
     7261 ttgcatcctg gaagattgcg tagcttgagt tcagaccacg accctgcaag aacatacggc
     7321 gcagtgaagt acctgaacct ttcggagcaa ccaggattac gtctacatca gcaggaggga
     7381 tgatgtttgt acgttctttg taagtgatac cgaatccgtg agagaaatac aaagccttac
     7441 ccggagtcag gtattttttg atgcgcggcc aaacttcaat ctgagcagca tctgaaagca
     7501 gatactggat gatagttgct ttttcgcatg cttcttcgat atcgaacagt gtttcgcccg
     7561 gtacccaacc gtcagcaacg gccttttccc aggtcttacc acctttacgt tgtcctacaa
     7621 ttacgttaaa accgttgtcg cgcaggttca ggctctggcc aggaccttgt acgccgtaac
     7681 ctattacagc gattgtttcg tctttcaata cttctcttgc cttttccaac ggaaattctt
     7741 cgcgggttac tacgttttcg tcaacgccgc caaaattcat tactgccatt ttctttttac
     7801 tattaaaatg tatataaaat aatttgtttt tcagatccag gtaacggcag cgcggctgat
     7861 ggctttgccg tcgttacaga ttgccatatt atatttatcg agggatactt cctggttatg
     7921 gagagtcagc tccatcccat actttccttc ggactgataa gctatttcga aacggcttat
     7981 ctctttttct cggaacagac tgatatcgaa caagtcgagc aggtgttcca tgtatttgat
     8041 actgttcagg tggccgttta cgtccaggtc actatacttc acacggtaag gttcgccgga
     8101 agtgttgttt tccaccggag caattttacc cggtttttca atcggacagg gacggtcggt
     8161 gatataagca ctcaggccct ccacatcgag caaggtcggg cggcgggttt ccatatcgat
     8221 agccgcccag atagagcggg caaagccaaa ggtcttgcct tcgccgttca ccagttcaaa
     8281 gcaacggctg gtaaacaact taccgacctc atccacccag gtatataaag ttacggattc
     8341 agacatggca ggataagaag tcatctcgat agccagacgg gaaagaaccc aggcggtatg
     8401 cctttcggtc atatcgttat atccgaatcc acggtcggcg gcatggcaag aagcagcatg
     8461 caacaaataa gttccgatca tagggattgt aatacgtccc cggaagtccg tcagataaga
     8521 ctctgttacg aaatgaaatt ctcctacttt gttcttctcc ataatttact ttatttacaa
     8581 aatgtttcct tattattctc agacatgttt ttcctgcaac ttcttttcca ttgcagataa
     8641 catgtcgctc agacgttcta ccttactctt cgttatagca acgcgtccgg aacggataaa
     8701 ttgcaggaca ccgatcgtct cactcaattc tttaaacaaa gcctgtgtct catcataatg
     8761 accactcttt tccaacacca cacaatcctc attcatttca aggatacggg cattgtactt
     8821 acggatcaga tcctcaaccg tccccatctt gataaagagt tcggtactca gtttataaag
     8881 agcgatttcc tggtaaacca ggtcttcatc cgtattataa taggctttca ggatatccac
     8941 acgcttgtcg atctgtttta cgaccttgtc gatcgtatcc tcgtcggcaa aggtagtaat
     9001 tgtaaactta tgtattccct ttatagcaga gggagaaaca gaaagcgtct caatgttcag
     9061 ttgccggcgc gtaaagataa cagttatctg attcagaaga ccaacagtgt tttccgaaaa
     9121 gataataacg gtatataatt gttttgtatt catagtttct cctccttact tatcacccaa
     9181 aatcatgttt gtcacgcttc ctccggccgg aaccatcgga tataccatac cacaagtttc
     9241 cacattggca accaacatat aggcaccatc gtgattcaac atttcagcaa tcgcctcatc
     9301 caagtcttcc cgtttatcta ccgcacggga agcaatacca aaagccttgg ctatcgctac
     9361 aaaatccgga ttcttcatga tggtattcga ataccgttcg ttgaagaaca gctcctgcca
     9421 ctggcgtacc attcccagga aattgttgtt aagaacgatg atctttacat tcagattttc
     9481 ctgcatgata gttcccaact cctggatagt catctggata ccaccgtcgc cggtaaagaa
     9541 acagaccgta cggtcaggcg ctcccagctt cgctccaatg gcggcgggaa ggccaaagcc
     9601 catcgttccc aaacctcctg aagtaactac gctgcgtgtt tgtttatatt tgaaatagcg
     9661 aacacccatc atctggttct gacctacatc cgtaaccaga atcgcatcat tatcggttgc
     9721 ttcggaaacc ttacggacta cttcgcccat tttcagttgg ccttcggtag gatagagttc
     9781 tttttctatt accttattat attcctcttt ttcatccggt tcgaattcag cattccattc
     9841 cggacgcttc cgttcttcca gtaaagccgt aatcatcgga atcgtatgct tggcatttcc
     9901 cagcactttc acgtcgaccg gcacattctt tccgatctcc gaattgtcga tatccaggtg
     9961 gataatcttt gcctgcttgg cataagtctt caggtcgccg gttacgcgat catcgaaacg
    10021 cataccgata gcaatcagca cgtcacattc gtttgtcttg cggttcggtc cgacatttcc
    10081 atgcatcccc aacatacctt tatttaatgg gaagtccgaa ggtaatgcag acaagcccaa
    10141 tacggtagaa ccggctggta tatcgttttt caacaagaat tctttcagtt cttcttcagc
    10201 tcctcccagg ataaccccct gccctaccag acagaatggc tttttggcat tatttatcaa
    10261 tgaagcagcc gcctcgatac gttcctccct gatatccggt tcaggttggt aactacgaac
    10321 ataatccact ttctgatact cataatctac caaacccacc tgtgcatctt tcgccaaatc
    10381 cagtaccaca ggtcccgggc gaccggtcga tgcgatatag aaagcacggg aaacggccca
    10441 agcaatttct tccgggcggc gtatctggta agcccatttg gtaatcggtt gtgtgatacc
    10501 gatcacatca acttcctgga aagcatctgt tccaagcagc ggagacggaa cctggccggc
    10561 aatcaccacc atcggtgtac tgtccatcag cgcatcggca ataccagtga tggtattggt
    10621 tgccccggga cccgaagtaa ccaccgttac tcccactttt ccggaaacac gggcatatcc
    10681 ctgtgcagca tgtgttgcac cttgttcgtg gcgcaccaga atatgtttta actgatctct
    10741 gtaatcgtat aaactatcgt aaattggtat cgcctgccca cccggataac cgaagatagt
    10801 atctactcct tcagcgatca gcgctttcag caaagcttcc gaaccggtta tcttttgttt
    10861 gtccatctct aaaatatagt atttggtgtt tattaatctt ctactattcg tacaccgccc
    10921 ttatcggccg aagcaaccat ctttgcatat gctttcagtg ctttcgatac cgtacgttgg
    10981 cggaaaggag gtgtaaaggc ttttgttccg cgggcttctt ccgcttcacg gcgtttggcc
    11041 agttcttcgt ctgtcacctt tacatgtatg gttctttcgg gaatattaat ttcgataata
    11101 tcgccgtctt tcactaagcc aatcgctccg cctgcagccg cttcgggaga aatatgtccg
    11161 attgacaaac ccgatgttcc accgctgaag cgtccgtctg tgattaacgc acattcttta
    11221 cccagatgtt tactctttat ataagaggta ggatacaaca tttcctgcat acccggacca
    11281 cccttaggac cttcataggt gataacgacg acatcgccgg agacgacttg atctttcagg
    11341 ataccttcgc aagcggcatc ctgcgaatcg aatactttgg cagggccggc aaaacggaag
    11401 atactttcat ctaccccggc tgttttaacc acacaaccgt cctgtgcaat atttccatac
    11461 agaacagcca gaccgccgtc tttcacataa gcatgttcca catcgcggat acatccggtt
    11521 gcacggtcgg tatccagttc tttataataa ctttcctgcg atccgagcac cagattgaaa
    11581 cggtgggccg gagcactttt ataaatattg attgcttctt ccgttacatt tacagaggta
    11641 atgcagtatt ggtcgatagc ctcattcaaa gtcagaccat ccgcacgttt cacggaaccg
    11701 tccaccagac cggcttttac cagctcattc ataataccga taatacctcc ggcacggttc
    11761 acatcttcca catgataaga acaactcgga gccactttac agataaccgg tgttttgcgt
    11821 gaaagcatat cgatgtcttt cattgtaaaa tcgacttccg cttcatgagc cacggccaac
    11881 aggtgaagga ctgtattcgt cgatcccccc atggcaatat ccagcgacat agcattcaga
    11941 aaggcctgac gggtggcaat actgcgaggc aatacggaat catcgccgtc acgataatat
    12001 ttaaaggcat tatcaacaat catcttcgcg gcttttttga acaggcgggt acggttggca
    12061 tgtgttgcaa caactgttcc gttgccggga agagccaatc caatcgcttc gttcagacag
    12121 ttcatagagt tagccgtgaa cataccagaa cagcaaccgc aggtcgggca agcggaacgt
    12181 tccacctttt ctacttgttc atcgctgata gaatcgtcag ccgcttcaat catggcgtcg
    12241 atcaaatcga gtgcacgtcc gtccagatta ccggcttcca tcggaccgcc ggatacaaag
    12301 attgtcggaa tattcagacg catactggcc atcagcatac ccggagtaat cttgtcgcag
    12361 ttactgatac aaaccattgc atcagcctta tgcgcattca ccatatattc cacactgtca
    12421 gcaatgatgt cgcgggaagg cagagaataa agcattccgt cgtgtcccat agcaataccg
    12481 tcatcaatag cgatcgtatt aaattctgcg gcaaagcaac cgagcttttc gatttccgct
    12541 tttacctgct gtccgatctc gtgtagatgc acatggcccg gtacaaactg ggtaaatgaa
    12601 ttcacaatgg caatgatcgg tttaccgaac tgttcttctt tcatgccgtt ggcacgccat
    12661 aatgcacggg ctccggccat acgtctgcct tctgtgctat aggagcttct taacggattc
    12721 ttcatcatat ctgtttttat cttttagtca ataaaaaagc ccttctctat atggagaaag
    12781 gcttaagaaa tatcttttac gacttcacaa cttcttacac acctttctcc ttacctacta
    12841 atgactagaa ggaccaccac gagaataata tgtaatacat tgttcatcat cttttcttat
    12901 cgtctttatt ttgtttgacg ctgcaaatgt agaataataa
//
