LOCUS       c00317_gnlPro..         4150 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HGEBOGJN_317.
ACCESSION   c00317_gnlPro..
VERSION     c00317_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 17:00:59
            Original ID  :: gnl|Prokka|HGEBOGJN_317
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 4150
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..4150
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1200:4150]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1201..4150
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..4150
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..4150
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             206..1045
                     /locus_tag="ctg317_1"
                     /transl_table=11
                     /translation="MHKGLLVVGRGIGQVMFQGNALSGLLMLIGIACSSWTLALLALAG
                     NIASTLAAYLLGYSREDIREGLYGFNGTLVGIAIGVFMRINIGSISLLLMGSALSSGIA
                     RQFNRQNKLPGYTAPFILSVWILLILCRYLFPSLMLPTVATPPGHVPDLLHAFTANIGQ
                     VMFQGNMLTGLFFLLAILVNSRLNAAYTIWGASLPLGMILLPATSIADFNMGLLGYNGV
                     LCAIAAGNHLSIRSLIRATLAILLSIGLQIGGMRLGITTLTAPFVLSVWITNLIIKE"
     CDS             complement(1201..2244)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg317_2"
                     /sec_met_domain="IlvN (E-value: 7.8e-48, bitscore: 150.6,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 1.1e-39, bitscore: 124.5,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQMNFGGVVENVMTREEFPLEKAREILKDETIAVIGYGVQGPGQ
                     SLNLRDNGFNVIVGQRQGKTYEKAVEDGWVPGETLFGIEEACDKATIIMCLLSDAAVMS
                     VWPTMKPYLTAGKALYFSHGFAITWNDRTGVVPPTDIDVIMVAPKGSGTSLRSMFLEGR
                     GLNSSFAIYQDATGKAMDRTLALGIGIGSGYLFETTFIREATSDLTGERGSLMGAIQGL
                     LLAQYEVLRENGHTPSEAFNETVEELTQSLMPLFAKNGMDWMYANCSTTAQRGALDWMG
                     PFHDAIKPVVEKLYANVKCGNEAQISIDSNSKPDYREKLEAELKALRESEMRQTAVTVR
                     KLRPENN"
     CDS             complement(2294..3019)
                     /locus_tag="ctg317_3"
                     /transl_table=11
                     /translation="MEKVGLFHFVAEPYLMDFRGRVTLPMIGNYLIHAASSHAGERGFG
                     FNDMSERHTAWVLSRLAIEMKEYPTAFDKINLYTWIDEVGRLFTSRCFELADENGKTFG
                     FARSIWAAIDVETRRPTLLDVEALGKYIDERPCPIEKPGKIMPAENKAEGIPYSIKYSD
                     LDINGHFNSVKYIEHLLDLFDIDQFKTREIGRLEIAYQSEGKQGMPLTLHKAESAPDKQ
                     DMAICHEGKAICRAAVTWR"
     CDS             complement(3026..3580)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg317_4"
                     /sec_met_domain="ALS_ss_C (E-value: 6.1e-18, bitscore:
                     53.4, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTKKLYTVIIFSENIVGLLNQITIIFTRRQLNIETLSVSPSAIK
                     GIHKFTITTFADEDMIDKVVKQIDKRVDILKAYYNTDEDLVYQEIALYKLSTELFIKMG
                     TVEGLIRKYNARILEMNETCVVLEKSGHYDETQALFNELSETIGVLQFIRSGRVAITKS
                     KVERLSDMLADMERKLHEKQQ"
     CDS             complement(3596..4150)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg317_5"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.1e-52, bitscore:
                     165.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="TGNDAVLVTDVGQNQMMGVRYFKYKQTRSVVTSGGLGTMGFGLPA
                     AMGAKFGAPDRTVCFFTGDGGMQMTIQELGTIMQEKLNVKIIILNNNFLGMVRQWQELF
                     FHERYSNTIMENPDFVAIAKAYGIAGRAVEKREELDDAIAEMLNHDGAYVLVANVETCG
                     MVYPMVPAGGSVTNMIMGDEK"
ORIGIN
        1 ttcgtatctc ttataacaag agccaaagtt agatatttaa tcctaacaaa caaaaatata
       61 agcggttatt tgcaaaaaaa cgcaaaagaa acaggttgac gatcatgccg caaaacatat
      121 cgtaaccgga atcttggcac agttgcccga attacgctcg tgattgtgct attttcgtta
      181 ttttcgcagt caaaactaaa atggtatgca taagggatta ctcgttgtag gccggggaat
      241 cggtcaagtg atgtttcaag gcaatgctct ttccggacta ttaatgctga taggtattgc
      301 ctgtagttca tggactttag cgttattggc gttagccggc aatatcgcaa gcacgctggc
      361 ggcctatctc ctcggatatt ctcgcgaaga tatacgcgaa ggactatatg gtttcaacgg
      421 aacactggta ggtatagcga tcggagtatt catgagaata aatatcgggt cgatatctct
      481 gcttcttatg ggatccgcct tatcaagcgg gatcgcccgg caattcaatc gccagaataa
      541 actaccggga tatacagccc cattcatact ttcggtatgg attttattaa tcctatgtcg
      601 atatctattc ccttcgttga tgcttccaac cgtagcgact cctcccgggc atgtccccga
      661 tttacttcat gctttcaccg ctaacatcgg acaagtgatg tttcaaggca atatgctaac
      721 agggctattc tttcttcttg ccatcttagt aaactcacgc ttaaacgcag cctacacaat
      781 atggggcgcg tcgctgccat tggggatgat attactaccg gcgacaagca tcgctgattt
      841 taacatgggg ttgctcggct acaacggtgt attatgcgct atcgcggcag gcaaccatct
      901 ttctatccgt agcctgatac gggcaacctt ggcgatctta ctatctatcg gattacagat
      961 tggcggcatg cgtctgggga tcacgaccct taccgcccca ttcgtactct ccgtatggat
     1021 aacaaacctt ataataaagg aatgattcca gcatcatcca tttaataatg attacgacta
     1081 tgacgaaatt aagcaacatc cccgtaaaag aaacagcggc caaggccgca aggacacgca
     1141 aggcgagcca cccgtaagtg acccgcctct ttttgctgat atataaggat taagattgga
     1201 ttagttgttc tccggacgaa gcttgcgtac ggtaacagca gtctgccgca tctcgctctc
     1261 gcgcaacgcc ttcaattcag cctccaattt ctcacgataa tccggcttag agttagaatc
     1321 gatagagatc tgagcctcgt taccgcattt tacgttcgca tacaatttct cgacaaccgg
     1381 cttgattgcg tcgtggaacg gacccatcca gtccaaagcg ccacgctggg cagtcgtaga
     1441 gcagttagcg tacatccagt ccataccatt cttggcgaat aagggcatca aggattgagt
     1501 caactcctcg accgtctcgt tgaaagcctc ggaaggagta tgtccattct cgcgcaatac
     1561 ctcatactgg gccaacaaca aaccttggat agcgcccatc aaagaaccgc gctcaccggt
     1621 caagtcggaa gtagcctcac ggatgaaagt cgtctcgaac aaataaccgg aaccgatacc
     1681 gatacccaac gccaacgtac gatccattgc cttgccagta gcgtcttgat agatagcgaa
     1741 agaagagttc aagccacgac cctcaaggaa catggaacgc aaagacgtac cagacccctt
     1801 cggagcgacc atgatcacgt caatatccgt gggaggaaca acgcccgtac gatcgttcca
     1861 agtgatcgcg aaaccatgag agaaatacag ggccttgcca gctgtcagat aaggcttcat
     1921 cgtaggccat acagacatta cggcagcgtc ggacaataag cacatgatga tcgtggcctt
     1981 gtcgcaagcc tcctcgatac cgaacagagt ctcacccgga acccatccgt cctcaaccgc
     2041 tttctcgtaa gtcttacctt ggcgctggcc aacgattacg ttgaagccat tgtcacgaag
     2101 gttcaatgac tgtcccggtc cctgtacgcc atagccgata acagcgattg tctcatcttt
     2161 taatatctct cttgcctttt ccaacggaaa ttcctcgcgg gtcattacat tctctacaac
     2221 accgccaaaa ttcatttgtg ccattttctt tttaactatt aatgtttaaa aacctattta
     2281 tgtatctctt ttattatctc caagtaaccg ccgcacgaca gatcgccttt ccctcatggc
     2341 aaatagccat gtcttgctta tcgggagcgg actccgcctt atgaagcgta agcggcatac
     2401 cttgtttacc ctcggattgg taggcgatct ccagacggcc gatctcacgg gtcttgaact
     2461 ggtcgatatc gaacaaatcc agcagatgct cgatatactt cacgctattg aagtgaccgt
     2521 tgatatccaa gtcgctgtat ttgatcgaat acgggattcc ctccgcctta ttctccgccg
     2581 gcatgatctt gcccggcttc tcgatcgggc acggacgctc gtcgatatat ttgcccaatg
     2641 cctctacatc caataaggta ggacggcggg tctccacgtc gatagccgcc caaatagaac
     2701 gggcaaatcc aaaggttttc ccattctcat ccgccagctc aaaacaacgg ctggtgaaga
     2761 ggcgtccgac ctcatcgatc caagtgtata gattaatctt atcgaaggcg gtaggatatt
     2821 ccttcatctc gatagccaga cgggacaaca cccaagccgt atgacgctcc gacatatcat
     2881 tgaaaccgaa cccacgctct ccggcatggc tggaagcggc gtgaatcaaa tagttaccaa
     2941 tcatagggag cgttacacgt cccctaaaat ccatcaaata cggctccgcc acgaaatgaa
     3001 ataatcctac tttctccata tcttattatt gttgcttttc atgtaacttt cgctccatat
     3061 cggccaacat atcgctcaag cgctccacct tgctcttcgt gatagccaca cgtccggagc
     3121 ggatgaattg caggacaccg atcgtctcgc tcaactcatt gaacaaggct tgtgtctcgt
     3181 cataatggcc actcttctcc aataccacgc aggtctcgtt catctccaag atacgagcgt
     3241 tgtatttacg gatcaatccc tccacggttc ccatcttgat gaaaagctcg gtacttagct
     3301 tataaagagc gatctcttga taaaccaaat cctcatccgt attataataa gccttcaaga
     3361 tatccacacg tttatcgatc tgtttcacca ccttatcgat catatcctca tcggcgaatg
     3421 tcgtgatcgt aaacttatgg atgcccttga tagcggacgg agagacggac agagtctcga
     3481 tgttcagctg tcggcgtgta aagataatcg ttatctggtt caaaagacct acgatattct
     3541 ctgaaaagat aataacggta tataatttct ttgttgtcat agcttcatct cctccttatt
     3601 tctcgtctcc cataatcatg tttgtcacgc ttcccccggc aggaaccatc ggatatacca
     3661 ttccgcaagt ctccacgtta gcgaccaaca cgtaagcgcc gtcgtggttt agcatctcag
     3721 cgatagcgtc gtccagctcc tcccgctttt caacggcacg gccggcgata ccataggctt
     3781 tagcgatcgc cacgaaatcc ggattctcca tgatggtgtt tgaataacgc tcgtggaaga
     3841 acaattcttg ccactgacgt accataccta agaagttatt attaagaatg ataatcttca
     3901 cgttcagttt ttcctgcatg atggtaccca attcttgaat cgtcatctgc atacccccat
     3961 caccggtaaa gaagcagacc gtacggtccg gagctccgaa cttagcgccc atagcggccg
     4021 gcagaccaaa tcccatcgta cctaaaccac cggaagtcac cacgctacgg gtttgtttat
     4081 atttgaaata gcggacgccc atcatctggt tctgcccaac gtcggtcacc aatacagcgt
     4141 cgttaccggt
//
