LOCUS       c00100_gnlPro..        15120 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OIMCGLIN_100.
ACCESSION   c00100_gnlPro..
VERSION     c00100_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 14:55:52
            Original ID  :: gnl|Prokka|OIMCGLIN_100
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15120
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15120
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[8320:13470]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      8321..13470
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..15120
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15120
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             complement(2..241)
                     /locus_tag="ctg100_1"
                     /transl_table=11
                     /translation="MMKNIFQDLKRKDHKRYLGGLDVFKYIGPGLLVTVGFIDPGNWAS
                     NFAAGSEFGYSLLWVVTLSTIMLIVLQHNVAHLGI"
     CDS             complement(403..648)
                     /locus_tag="ctg100_2"
                     /transl_table=11
                     /translation="MEYVYRTQGTCSTNIELNVEDGVVKEVAFWGGCNGNLQGLSRLVK
                     GMKVEEVIKKLEGVRCSGRPTSCPDQLCHALHEMGY"
     CDS             complement(656..1399)
                     /locus_tag="ctg100_3"
                     /transl_table=11
                     /translation="MGRAFEYRKAAKLKRWGHMAKTFTRLGKQIAIAVKAGGPEPENNP
                     TLRSVIATCKRENMPKDNIERAIKNAMGKDQSDYKSMTYEGYGPHGIAVFVDTLTDNTT
                     RTVADVRSVFNKFGGNLGTMGSLAFLFDHKCMFTFKIKDGMDMEELILDLIDYDVEDEY
                     EQDDEEGTITIYGDPKSYAAIQKHLEECGFEDVGGDFTYIPNDLKEVTPEQRETLDKMI
                     ERLEEFDDVQTVYTNMKPEEGGNEE"
     CDS             complement(1435..3897)
                     /locus_tag="ctg100_4"
                     /transl_table=11
                     /translation="MNISYNWLKEYVNFDLTPDETAAALTSIGLETGGVEEVQTIKGGL
                     EGLVIGEVLTCEEHPNSDHLHITTVNLGDGEPVQIVCGAPNVAAGQKVVVATLGTKLYD
                     GDECFTIKKSKIRGVESTGMICAEDEIGIGTDHAGIIVLPAEAVPGTLAKDYYNIKSDY
                     VLEVDITPNRADACSHYGVARDLYAYLIQNGKQATLQRPSVDGFKVENHDLDIEVVVEN
                     SEACPHYAGVTVKGVTVKESPEWLQNKLRLIGVRPINNVVDITNYIVHAFGQPLHCFDA
                     GKIKGNEVIVKTLPEGTPFVTLDEVERKLNERDLMICNKEEAMCIAGVFGGLDSGSTEA
                     TTDVFIESAYFHPTWVRKTARRHGLNTDASFRFERGIDPNGVIYCLKLAALMVKELAGG
                     TISSEIKDVCVAAPQDFMVELSYEKVNSLIGKVIPVETIKSIVTSLEMKIMNETVDGLT
                     LAVPPYRVDVQRDCDVIEDILRIYGYNNVEIPTTLNSSLTTKGEHDKSNKLQNLVAEQL
                     VGCGFNEILNNSLTRAAYYDGLENYPSNHLVMLLNPLSADLNCMRQTLLFGGLESIAHN
                     ANRKNADLKFFEFGNCYYFDADKKNPEKVLATYSEDYHLGLWVTGKKVANSWAHPDENS
                     SVYELKAYVENILKRLGLDLHNLVVGNLTDDIFATALSVHTKGGKRLASFGVVTKKLLK
                     AFDIDNEVYYADLNWKELMKAIRSVKISYKEISKFPAVKRDLALLLDKNVQFAEIEKIA
                     YDTEKKLLKEVELFDVYEGKNIEAGKKSYAVSFLLQDETQTLNDKMIDKIMSKLVKNLE
                     DKLNAKLR"
     CDS             4037..4222
                     /locus_tag="ctg100_5"
                     /transl_table=11
                     /translation="MVGDKVAKNKGVFFVIFATYPYQNTTWLYSIKNNRPLDWSKSSGY
                     FHLTKRSFYSTQKMFF"
     CDS             complement(4219..5772)
                     /locus_tag="ctg100_6"
                     /transl_table=11
                     /translation="MAEQRRNSRNTKSTKVQPVNDYGRIQPQAPELEEAVLGALMIEKD
                     AYSLVSEILRPESFYEHRHQLIYAAITDLAVNQKPVDILTVKEQLSKRGELEEVGGPFY
                     ITQLSSKVASSAHIEYHARIIAQKSLARELITFTSNIQSKAFDETLDVDDLMQEAEGKL
                     FEISQQNMKKDYTQINPVIDEAYKLIQKAAARTDGLSGLESGFTKLDKMTSGWQNSDLI
                     IIAARPAMGKTAFVLSMAKNIAVDYRNPVALFSLEMSNVQLVNRLITNVCEIPSEKIKS
                     GQLASYEWQQLDYKLKDLLDAPLYVDDTPSLSVFELRTKARRLVREHGVRIIIIDYLQL
                     MNASGMAFGSRQEEVSTISRSLKGLAKELNIPIIALSQLNRGVESREGIDGKRPQLSDL
                     RESGAIEQDADMVCFIHRPEYYKIYQDDRGNDLRGMAEIVIAKHRNGAVGEVLLRFKGE
                     FTRFSNPEDDMVIPMPGEPAGAMLGSKLNAGAMPPPPPEPDFVPQGNNPFGATEGPLPF
                     "
     CDS             5971..6795
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GHMP_kinases_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GHMP_kinases_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg100_7"
                     /sec_met_domain="GHMP_kinases_C (E-value: 1.1e-09,
                     bitscore: 28.9, seeds: 112, tool: rule-based-clusters)"
                     /sec_met_domain="GHMP_kinases_N (E-value: 2.2e-10,
                     bitscore: 31.0, seeds: 447, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MITFPNAKINLGLSITEKRPDGYHNLETVFYPVALEDALEIRTSP
                     EADKKFSLHQYGMEISGNPEDNLVVKAYLLLDKEFHLSPIEIHLYKHIPSGAGLGGGSS
                     DAAFMLKLLNEHFQLNLSEDQLEIYAATLGADCAFFIRNAPTFAEGIGNIFSPIPLSLK
                     GYQILIIKPDVFVSTREAFANIHPHHPEYSIKEAIKRPANEWKEILINDFEDSVFPQHP
                     VIGEIKAELYRQEAVYASMSGSGSSVYGLFEPEGTLPETDWGTNVFRFKGRL"
     CDS             complement(7028..8062)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GDP_Man_Dehyd"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg100_8"
                     /sec_met_domain="GDP_Man_Dehyd (E-value: 1.2e-52, bitscore:
                     169.5, seeds: 258, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKERILVTGGTGYIGSHTVVELQNSGYEVIIIDNLSNSSADVVDN
                     IEKVSGIRPAFEKLDCLDFAGLDAVFAKYKGIKAIIHFAASKAVGESVEKPLLYYRNNL
                     VSLINLLELMPKHGVEGIVFSSSCTVYGQPDELPVTEKAPIKKAESPYGNTKQINEEII
                     RDTIASGAPINAILLRYFNPIGAHPTALLGELPNGVPQNLIPYLTQTAMGIREKLSVFG
                     DDYDTPDGSCIRDFINVVDLAKAHVIAIRRILEQKQKEKVEVFNIGTGRGVSVLELING
                     FEKATGVKLNYQIVGRRAGDIEKVWANPDFANQELGWKAVETLEDTLRSAWNWQLKLRE
                     RGIQ"
     CDS             complement(8321..8893)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg100_9"
                     /sec_met_domain="Rnf-Nqr (E-value: 3.4e-63, bitscore:
                     203.0, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYILIFISAIFVNNIVLSQFLGICPFLGVSKKVETAMGMSAAVA
                     FVLTIATIVTFLIQKFVLDAFGLGYLQTITFILVIAGLVQMVEIILKKVSPSLYQALGV
                     FLPLITTNCCILGVAILVIQKDFDLLTGVVYAFSTALGFGLALVLFAGLREQMTLVKIP
                     KGMQGTPIALITAGLLAMAFMGFSGVV"
     CDS             complement(8916..9482)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg100_10"
                     /sec_met_domain="Rnf-Nqr (E-value: 1.6e-70, bitscore:
                     226.9, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMNGIIKENPIFVLLLGMCPTLGTTSSAINGMGMGLATMFVLICS
                     NVVISSIKNLIPDMVRIPSFIVVIASFVTLLQMIMQAYVPDLYATLGLFIPLIVVNCIV
                     LGRAEAFAAKNNPLASMFDGIGMGFGFTIALTLLGAVREFLGTGKIFNLTILPEEYGML
                     IFVLAPGAFIALGYLIAIINSLKKA"
     CDS             complement(9518..10201)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FMN_bind"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg100_11"
                     /sec_met_domain="FMN_bind (E-value: 1.3e-23, bitscore:
                     73.8, seeds: 891, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLVLTGVTAVSVALLAYVNELTKGPIAEANAKTLNEALKKVLPE
                     YTNNPVAESDTVFSEKDGKKIVDFIIYPAKNGEKWVGSAVEAKSMGFGGELKVLVGFDA
                     EGKIYNYSLLAHAETPGLGSKADKWFGAYDPAKNEKPVSHEESAKSILGMNPGETPLAV
                     TKDMNGQVDAITASTITSRAFLNAVNAAYQAYKGGEVDTNSGASQKNEPAVAPEGEAAA
                     NDTNN"
     CDS             complement(10228..11220)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg100_12"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 8.1e-121,
                     bitscore: 393.1, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENKLIVSLSPHVHGGDSVQKNMYGVLIALIPAFLVSLYFFGLGA
                     LIVTATSVAACLFFEWAIVKFLMKKPATTICDGSAVITGVLLAFNLPSNLPIWIIILGA
                     LFAIGVGKMSFGGLGCNPFNPALAGRVFLLLSFPVQMTTWPVVGQLTSYMDATTGATPL
                     ALMKQAVHGDASALSQIPDALTLFIGQNGGCIGEVSALALLLGLVYMLWKKIITWHIPV
                     SIIVTVFVFAGIMHMVDPEKYVSPVLQLLSGGLMLGAVFMATDYVTSPMSKKGMLIYGV
                     CIGLLTVVIRLFGAYPEGMSFAILIMNAFTPLINTYCKPKRFGEVAKKK"
     CDS             complement(11227..12564)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_10"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg100_13"
                     /sec_met_domain="Fer4_10 (E-value: 1.8e-09, bitscore: 28.0,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 1e-16, bitscore: 50.9,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 3.7e-51, bitscore:
                     163.3, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 2.3e-30, bitscore: 94.9,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 3.6e-06, bitscore: 17.7,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKTFSIGGVHPHENKLSAHQPIITAEVPAKAVILLGQHIGAPAK
                     PIVAKGDMVKVGTKIAEPAGFVSAAIHSSVSGKVAKIDTVVDASGYAKPAIFIDVEGDE
                     WEETIDRSKTLVKECELSSEEIVKKIADAGIVGLGGACFPTQVKLCPPPSFKAECVIIN
                     AVECEPYLTADHQLMLEHAEEVMVGVSILMKAVKVNKAFIGIENNKPDAIELMTKVASS
                     YAGIEVVPLKVKYPQGGEKQLIDAITKRQVASGALPISTGAVVQNVGTAFAVYEAVQKN
                     KPLFERVITVTGKSVAKPSNFLARIGTPMKQLIDACGGLPEDTGKVIGGGPMMGKALVN
                     IEVPTAKGSSGILIMNQKEAKRGEAQTCIRCAKCVSACPMGLEPYLLGALSENGDFETM
                     EKERIMDCIECGSCQFTCPANRPLLDYCRLGKGKVGAMIRARQAKK"
     CDS             complement(12589..13470)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FeS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_17"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1016:4Fe-4S dicluster domain (Score: 38.6; E-value:
                     4e-12)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg100_14"
                     /sec_met_domain="Fer4_7 (E-value: 1.2e-12, bitscore: 38.6,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 3.9e-09, bitscore: 26.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 8.1e-09, bitscore: 25.6,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 3.8e-09, bitscore: 26.7,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_17 (E-value: 1.4e-08, bitscore: 25.6,
                     seeds: 82, tool: rule-based-clusters)"
                     /sec_met_domain="FeS (E-value: 3.4e-11, bitscore: 33.0,
                     seeds: 364, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 4.5e-06, bitscore: 17.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLILIAVISLGAIALVLAAILYVASKKFAVYEDPRIAQVGEVLP
                     QANCGGCGYPGCSGFADACVKAGSLDGKFCPVGGQPVMAQIADILGLAATEAEPMVAVV
                     RCNGSCANRPRINQYDGAKSCAIAASLYGGETGCSYGCLGCGDCVAACQFDAIHMNPET
                     GLPEVDEAKCTACGACVKACPKAIIEIRPQGKKSRRVYISCVNKDKGAVARKACTVSCI
                     GCGKCVKTCPFEAITLENNLAYIDPNKCKSCRKCVEVCPQNTIIELNFPPRKPKAEEAP
                     KTVAAEAPKVTE"
     CDS             complement(13477..13902)
                     /locus_tag="ctg100_15"
                     /transl_table=11
                     /translation="MTNNTIKHLGIVENIQGSHLSVRIVQTSACAACSAKGHCSSADSK
                     DKVIDITDVTAASYQVGERVMVIGETSMGMMAVTLAFIIPFVLLIVSLFAWMALIGNEL
                     YAALLSLAVLIPYYFVLWLNKTRMKQHFSFTIKPINN"
     CDS             complement(14133..14225)
                     /locus_tag="ctg100_16"
                     /transl_table=11
                     /translation="MKKTWSVVLKVIIAVAGAIAGVLGVQAASL"
     CDS             complement(14261..14782)
                     /locus_tag="ctg100_17"
                     /transl_table=11
                     /translation="MSVIYKVVTRPSDPRVPNSPKKYYPHLITLGQSVNLKYIAQKMQG
                     YSSLSIGDIKSVIQNFVEKMKEQLLEGKSVNIEGLGVFMLTACSKGADAAKDVNAKSVD
                     SVRIFFQANKELRITKTATRADEKLDLISLDEYLKKLNASVTPNDPDDGENGGGGNEGG
                     GDEEAPDPTV"
     CDS             complement(14939..15118)
                     /locus_tag="ctg100_18"
                     /transl_table=11
                     /translation="LINELSFEKKLPNLCTVINGVDLKKRKYGYYYGYGKYGKHYGYGK
                     RYGYGYGYGQDTKR"
ORIGIN
        1 caattcccaa gtgagcaaca ttatgctgga ggacaatcaa catgatagtg gataaggtga
       61 ccacccaaag aagtgaatag ccgaactcgg aacctgcggc aaaatttgat gcccagttgc
      121 ccggatcaat aaatccgaca gttaccaaaa gtccgggacc aatatattta aaaacatcca
      181 gtccgcccag atagcgttta tgatctttcc gttttaagtc ttgaaaaata ttcttcatca
      241 ttgcataata gtttattcag cacaaatata cttataaata acgaccgaag gtcgattttg
      301 gttcaaaata ccgacaaata gggaaaggta cggcacaata aaaaacctcc ggcaaaatga
      361 attgccggag gccagtgtat attttataaa gggagacttc cgttaatatc ccatttcatg
      421 cagtgcatgg cacaactgat cgggacagga cgtcggtctg ccactgcaac gtactccttc
      481 aagtttcttg ataacctctt ctaccttcat tccctttacc agacgtgaaa gtccctgaag
      541 atttccgtta catcctcccc aaaaggcaac ttccttcaca actccatctt ctacattcag
      601 ttcgatgttt gtgctgcaag taccctgggt tctataaaca tattccataa tccgcttact
      661 cctcgtttcc gccttcttcc ggcttcatgt ttgtataaac agtctgcacg tcatcaaatt
      721 cttcaagacg ttctatcatc ttatccaaag tttcgcgttg ttccggagtt acctctttca
      781 gatcgttcgg gatataagta aaatcaccgc cgacatcctc gaagccacac tcttcaagat
      841 gtttctgaat agcggcatag ctcttaggat caccgtagat agtgattgtt ccttcttcgt
      901 catcctgttc gtactcatct tctacgtcgt aatcaatcag atcaaggatc agttcttcca
      961 tatccatgcc gtcctttatc ttgaaagtga acatacattt atggtcgaaa aggaaagcca
     1021 atgatcccat tgttccgagg ttaccaccaa atttattgaa tacagagcgt acatcggcta
     1081 ccgtacgagt cgtattatca gtcagcgtat ctacaaagac agcaattccg tgaggaccgt
     1141 atccttcgta agtcatgctc ttgtagtcgc tctgatcctt acccattgca ttcttaatcg
     1201 cacgttcgat attgtccttc ggcatattct cacgcttaca agtagcgatg accgaacgca
     1261 gtgtcgggtt attttccggt tccggaccac ccgccttcac ggcaatagcg atctgtttac
     1321 ccagtcttgt aaatgtttta gccatgtggc cccatctttt cagctttgcg gcttttctat
     1381 attcaaatgc tcttcccatt ggtttgtatt aattttgaat tgtgaatttt aaatttatct
     1441 caattttgca ttcagcttat cttccagatt cttcaccagt ttagacatga tcttatcgat
     1501 catcttatcg ttcagcgtct gagtttcatc ctgaagcagg aagctgaccg catacgattt
     1561 cttacctgct tcgatgttct taccttcgta tacatcgaag agttccactt ctttcagcag
     1621 tttcttttct gtatcgtaag cgattttttc gatttcggca aactgtacgt tcttgtcgag
     1681 caacaatgcc aagtcacgct tcacagcagg gaatttggaa atttccttgt agctgatctt
     1741 cactgaacgg atagccttca tcagttcttt ccagttcaag tcggcataat acacctcatt
     1801 atctatatcg aatgctttca gcagtttctt cgtcacaaca ccgaaagagg caagacgctt
     1861 cccccccttg gtatgaacag aaagtgcggt agcgaaaata tcgtcagtca gattgccaac
     1921 taccaggttg tgcaaatcca gtcccaggcg cttcaatata ttctctacat aagccttcaa
     1981 ttcgtatacc gaactgtttt catccgggtg tgcccatgag ttggctactt tctttccagt
     2041 cacccacaaa cccaagtgat agtcttccga ataggtagcc agtacttttt ctggattctt
     2101 cttgtccgca tcgaagtaat agcaattacc gaattcgaag aatttcaaat cggcattctt
     2161 gcggtttgca ttgtgagcga tgctttccag tccaccgaac agcaatgtct gacgcataca
     2221 gttcagatcg gcactcagtg gattcagcag catcaccaga tggttggatg gatagttctc
     2281 cagaccgtcg tagtaagcgg cacgagtcag agaattattc agtatttcat tgaagccaca
     2341 gccaaccaac tgttctgcaa ccagattctg taatttgttt gatttatcat gctcaccctt
     2401 ggttgtcaga ctggagttca gcgtagtcgg gatttctaca ttattatatc cgtagatacg
     2461 tagaatatct tcgatcacat cgcaatcacg ctgtacgtct acacgataag gaggaacggc
     2521 taatgtcagt ccgtcaactg tctcattcat gattttcatt tccaggctgg taacaatgct
     2581 cttgatcgtt tccacgggaa tcactttacc aatcagcgaa tttactttct cataagaaag
     2641 ttctaccata aagtcttgtg gagctgcaac gcaaacatcc ttaatttcgg atgagatagt
     2701 gccaccggcc agttctttca ccatcagagc agccagtttc agacaataga ttactccgtt
     2761 cggatcgatg ccacgttcga aacggaaaga agcatccgta ttcagaccgt gacgacgggc
     2821 agtcttacgc acccatgtag gatggaaata agcgctttcg ataaatacat ctgtcgtagc
     2881 ttccgtagaa ccggaatcca gtccgccgaa tacaccggca atacacatcg cttcttcttt
     2941 gttgcagatc atcagatcgc gttcgttcaa cttgcgttcc acttcatcca atgtgacgaa
     3001 tggagtgcct tccggcaatg tcttgacaat tacttcattg ccttttatct ttccggcatc
     3061 gaaacaatgc aatggctgac cgaaagcatg aacgatataa ttagtaatat ccactacatt
     3121 attaatagga cgtacaccga tcaagcgcaa tttattctgc aaccattcgg ggctttcctt
     3181 cacagtaacg cctttcaccg taacgccggc atagtgagga caggcttcgc tgttttcaac
     3241 cactacttcg atatccaaat catgattttc caccttaaat ccatctacag atggacgttg
     3301 caaagtagcc tgcttgccat tctgaatcag gtaagcatac aagtcgcggg ccacaccata
     3361 gtgtgagcaa gcgtctgcac ggttaggagt aatatctact tcgagtacgt agtcactctt
     3421 gatattataa tagtctttgg cgagagtacc cggaacagct tcagccggca acacgatgat
     3481 tcctgcatga tcggtaccaa taccgatttc gtcttctgca caaatcatcc ctgtagattc
     3541 tacaccacgg atttttgact tcttgatagt aaagcattca tcaccgtcat aaagtttggt
     3601 acccaaagtg gcaaccacta ctttctgtcc ggcagctaca ttcggagcac cgcatacaat
     3661 ctgtacaggt tcgccgtctc ccagattgac ggtagtgata tgcaaatggt cggaattcgg
     3721 atgttcttcg caagtcagca cttcaccgat tacgagtcct tccaaaccac ccttaatggt
     3781 ttgcacttct tctacaccac ctgtttccaa gccgattgag gtcagcgcag cagccgtttc
     3841 atcgggggtc aaatcaaagt tgacatactc tttcagccag ttataagaga tattcatata
     3901 attaaatttt tattgtttct caaaaagttt cgcaaagtta ataagatttt tcggttgaca
     3961 tagaacgatt tgagagaaaa atgtcaagag aagctaaact aacaaggacc tgactgtatt
     4021 attccccaat aaattcatgg ttggtgacaa agtggcaaaa aacaaagggg tattctttgt
     4081 catttttgcc acctatccct atcagaatac aacttggcta tactctataa aaaataatcg
     4141 accgctcgat tggagtaaat cgagcggtta ttttcatctg actaagcggt cattctattc
     4201 aacccaaaag atgttttttt agaaaggtaa cggtccttcc gttgcaccga acggattatt
     4261 tccctgcgga acaaagtccg gttccggcgg aggcggaggc atagcaccgg cattcagttt
     4321 agaccccagc atggcacctg caggttcacc cggcatcggt ataaccatat catcttccgg
     4381 attagagaat cgtgtaaact cacctttgaa tcggagcaag acttcaccta ccgcaccatt
     4441 acgatgcttg gctatcacaa tttccgccat accgcgcagg tcgttaccac gatcatcctg
     4501 ataaatctta taatattccg gacggtgaat aaaacacacc atatcggcat cctgctcgat
     4561 ggctccggat tcacgaaggt cactcaactg agggcgttta ccgtcaatac cttcacgact
     4621 ctccacacca cgattcaact gcgacaaggc tataatggga atgttcaact cctttgccaa
     4681 tcctttcaac gaacgggata tcgtactaac ctcttcctga cggctaccga atgccatacc
     4741 actcgcattc atcaactgaa ggtagtcaat aataatgatt ctcaccccat gttcacgcac
     4801 cagacgacgt gctttggtcc ggagttcaaa cacagacaaa gacggagtat cgtccacata
     4861 aagcggagca tccagcaggt ctttcagttt gtagtccaac tgttgccact catagcttgc
     4921 caattgtcca cttttgatct tctcactcgg aatctcacaa acattggtga taagacggtt
     4981 gaccaactgg acgttactca tttcaagaga gaacaacgct accggattcc gataatcaac
     5041 agcaatattc ttagccatag aaagtacgaa agctgtctta cccatggcag gacgggcagc
     5101 gattataata aggtcggagt tctgccaacc ggaggtcatc ttgtccagtt tcgtaaatcc
     5161 actttcaaga ccactcagac cgtccgttcg tgcagccgct ttctgaatca gcttatacgc
     5221 ttcgtcaatt accggattaa tctgcgtata gtctttcttc atattctgct gggaaatctc
     5281 aaacagcttg ccttccgcct cctgcatcaa gtcgtccaca tccagtgtct catcaaaagc
     5341 cttgctttga atattactgg taaacgttat caattcgcgc gccaacgatt tttgtgcaat
     5401 aatacgggcg tgatattcga tatgtgcgga agaagcaacc ttactgctca actgagtaat
     5461 atagaacggt ccaccgacct cttccaactc acctcttttg ctcaactgct ctttgaccgt
     5521 cagaatgtcc accggcttct gattaacggc aagatcagta atggcagcat aaatcaactg
     5581 atgacgatgc tcataaaatg actccgggcg aagaatctca ctcaccagcg aataagcatc
     5641 cttctcaatc attaaagcac ccaacaccgc ctcttccagc tccggtgcct gaggttggat
     5701 acgaccataa tcattgaccg gttgtacttt agttgatttt gtgttacggg aatttcttct
     5761 ttgttcagcc atctgcttat atacaatttt atgatttaca atttatgatc cccggctttt
     5821 atacatagta aaatccgaaa gggatgacaa agatagaata taataatgaa gaaaagataa
     5881 ggaaaaatga agattttagt aactttgtca ccaatagcat aaattcgcaa cccataattt
     5941 aaaattcaaa aataataatt cagaacgaat atgatcactt tcccaaacgc aaaaataaac
     6001 ctgggactct ctattaccga gaagcgtccg gacggatatc acaacctcga aaccgtattc
     6061 taccccgtcg ctctcgaaga tgcgctggaa atccggacca gccccgaagc ggacaaaaag
     6121 ttctccctgc atcagtacgg aatggagata tccggtaatc cagaagacaa tttagtggtg
     6181 aaagcatatc tgctattaga taaagagttt cacctctctc ctatcgagat ccatctgtac
     6241 aaacacattc cttccggtgc cggactggga ggaggctcat cagacgcagc tttcatgctg
     6301 aaattactca acgaacactt tcagctgaat ttatccgaag atcagctgga aatatatgcc
     6361 gcaactttgg gagcagactg cgctttcttt atcagaaacg ccccgacctt tgccgaagga
     6421 atcggcaaca tattctcccc cattccacta tccttaaaag gatatcagat tctgatcatc
     6481 aaaccggatg tattcgtatc aacgcgggaa gctttcgcca atattcaccc tcatcatccc
     6541 gaatactcga tcaaagaagc gatcaaacgc ccggcaaatg aatggaaaga gatattaatc
     6601 aatgattttg aagacagcgt attcccccag catccggtga tcggagaaat taaagccgaa
     6661 ctatacaggc aagaggctgt ttatgcctct atgagcggtt ccggttcttc cgtatatgga
     6721 ttgttcgagc cggaaggaac tttacctgaa accgattggg gaactaacgt attccgtttt
     6781 aaaggcaggc tgtaaaggag taacaaaaaa cggtaccacg actcccgtcg tagtaccgtc
     6841 acaacacaaa cacaaaataa aacacgacaa aactactatg caatcatacc tgtctatgcc
     6901 ggagaggcat aagtaccatt tactcatatt cacatactca caaacagatc aagctgatta
     6961 gcatctaata aacaaatcgc atgaacgatt tgtttaaact tttatgttaa ttaaaacaaa
     7021 tatcttttta ctgaatgcct ctttcacgga gtttcagctg ccaattccat gcagagcgta
     7081 aagtatcttc taatgtttct accgctttcc aacccagttc ctggttggca aaatcggggt
     7141 tagcccatac cttttcaata tcacctgcgc gacggcctac aatctgataa ttcagtttaa
     7201 cgccagtagc tttttcaaag ccattaatca gttccaatac tgaaacaccg cgtcctgtac
     7261 cgatattgaa tacttctact ttttctttct gtttttgctc caaaatacgg cggattgcaa
     7321 tcacgtgtgc tttagccaag tcaacaacgt tgataaagtc acggatacaa gaaccgtcag
     7381 gagtatcata atcgtcaccg aatacactta gtttttcacg gatacccatc gctgtctgag
     7441 tcagataagg aatcaggttt tgaggaacac cgttcggaag ttcacccagc aatgctgtag
     7501 gatgtgcgcc aatcggattg aaataacgca gcaaaatagc attgatcggg gcaccggaag
     7561 ctattgtatc acggataatt tcttcattaa tctgttttgt atttccataa ggagattccg
     7621 ctttcttgat cggagccttt tccgttacag gcaactcatc cggttgacca tatactgtac
     7681 aggaagaaga gaacactatg ccttctactc catgtttagg cattaactcc agaaggttga
     7741 ttaaagaaac caggttgtta cgataataaa gcaacggctt ctctaccgac tctcctactg
     7801 ctttgcttgc tgcgaaatga ataatcgctt taattccttt atatttggca aatacggcat
     7861 caaggccagc aaaatcaaga caatccagtt tctcaaaagc tgggcggata ccggatactt
     7921 tctctatatt gtcaacaacg tcagcactcg aatttgataa attatcgata atgattactt
     7981 cgtatccact gttttgtagt tctacaacgg tatgagaccc aatatagcct gttcctcccg
     8041 ttactaaaat tctttctttc atataatttt aaaatatggt tagtttttcg gttttcagtt
     8101 tgtttgaggt acaaatgtat ggaaataaaa tggaaatgca ataaactatc gcaattttat
     8161 tcacaggaag atacttacgg gacgatttga gggcgttttg gtatgataaa aaacatattc
     8221 ggtatgaaca gatataaaga aaaaggccgg aaacaaactg cctgtatgtt gccatacgac
     8281 agagtttcca gcctctttat ctaattatca acttagtctt ttacacgacg ccagagaagc
     8341 ccatgaatgc cattgccagc aaacctgcgg taatcaaagc aatcggagtc ccctgcattc
     8401 ctttcggaat cttcaccagg gtcatctgct cacgcaatcc ggcaaacaat accagtgcca
     8461 gaccaaagcc aagagcagta gagaatgcat atacaacacc tgtcagcaga tcaaagtctt
     8521 tctggattac caggattgcc acaccgagaa tacagcagtt cgttgtaatc aacggcagga
     8581 acacccccag tgcctgatac aaagaaggag aaactttctt cagaataatt tctaccatct
     8641 gcaccagtcc ggcaataacc agaataaaag tgattgtctg taagtacccc aatccgaaag
     8701 cgtccaacac aaacttctga atcaggaatg tgacgatggt agcgatagtc agcacgaaag
     8761 caactgccgc actcataccc atcgctgttt ccaccttctt ggaaacaccc aggaacggac
     8821 agattcccag gaactgcgac aacacaatgt tgtttacaaa gattgccgag ataaatatca
     8881 atatatattc catattcttt tcttatttaa tagagttagg ctttcttcag actattaata
     8941 atggcaatca gataacctaa agcgataaag gcacccggag ccaaaacaaa gatcagcatt
     9001 ccgtattctt ccggcagaat ggtcagatta aatatcttac ctgttccgag gaattcacgt
     9061 acggcaccca acagagtcag ggcaatggta aaaccaaatc ccataccgat accatcaaac
     9121 atagaagcca gcggattgtt cttcgctgca aaagcttccg cacgtcccaa tacgatacaa
     9181 tttactacga tcagcggaat gaaaagaccg agggtagcat acagatcggg cacgtatgct
     9241 tgcattatca tctgcaacag tgtcacgaat gacgcgatca ccacgataaa tgaagggatg
     9301 cgtaccatat ccggaatcag attcttgata gatgaaatta ccacgttcga gcaaatcagg
     9361 acgaacatag tggccagtcc catacccata ccgttgattg ccgatgatgt cgtacccagt
     9421 gtaggacaca taccgagcag gagcacaaaa ataggattct ctttgataat cccgttcatc
     9481 attactttaa aattattcat aactgtctcc tcctttctta gttattagtg tcattagcag
     9541 ctgcttcacc ttccggcgca acagccggtt catttttctg ggaagctccg gaattcgtat
     9601 ccacctcacc gcctttatat gcctgataag cagcattcac cgcattcagg aaagcacgtg
     9661 aagtgatagt agaagccgtg atagcatcta cctgtccatt catgtctttg gtcacagcca
     9721 atggagtctc tcccggattc atgcccaaaa tagactttgc actttcttcg tgagataccg
     9781 gtttttcgtt ctttgcagga tcataagctc caaaccattt gtccgctttc gaacccaatc
     9841 ccggagtttc agcgtgcgcc aataaagagt agttataaat cttgccttca gcatcaaagc
     9901 ccaccagcac tttcagttca ccgccaaatc ccattgactt ggcttcaacg gcagaaccta
     9961 cccacttttc gccattcttg gccggataga taatgaaatc cacgattttc tttccgtctt
    10021 tctcgctgaa aacagtatcg ctttcggcta ccggattatt ggtatattca ggaagcacct
    10081 ttttcaaggc ctcgttcagc gtctttgcat tcgcttcggc aatagggcct ttcgtcagtt
    10141 cgttcacata agccagcaac gctacggaaa cagctgtaac gcccgtaagt accagcaaca
    10201 tattctttaa agatgattgt aactttttca tttcttcttc gctacctccc caaagcgttt
    10261 aggtttacaa taggtgttaa tcagcggagt gaacgcattc ataatcagga tggcgaatga
    10321 cataccttcg ggatatgcac cgaacagacg gataaccacc gtcagcagac cgatacaaac
    10381 accgtaaatc agcatacctt tcttgctcat cggagaagtc acatagtcgg ttgccataaa
    10441 gacagctccc agcatcagac ctccggagag tagttgcaat accggagaaa catacttttc
    10501 gggatccacc atatgcataa tgcctgcaaa tacaaataca gtcacaatga tagaaaccgg
    10561 aatatgccag gtgatgatct ttttccagag catgtatacc agtccgagca acagtgccag
    10621 cgcacttact tcaccgatac atccgccgtt ctgtccgata aacagagtca gcgcatcagg
    10681 tatctggctc aaagcacttg catcgccgtg aacagcctgt ttcatcaatg ccagcggagt
    10741 agcaccggtg gtagcgtcca tataagatgt cagctgacct actaccggcc atgttgtcat
    10801 ctgcaccggg aaagaaagca acaggaatac acgtcccgcc aatgccgggt tgaatgggtt
    10861 gcagcccaga ccaccgaaag acatcttgcc tacaccaatt gcgaacagtg cacccagaat
    10921 gataatccag ataggcagat tggaaggtag attgaatgcc agcaacacac ctgtaatgac
    10981 agcagaaccg tcacaaatgg ttgtagcagg tttcttcatt aagaatttaa cgatcgccca
    11041 ttcgaagaat aaacaggctg ctaccgaagt agccgtgaca atcagagccc ccaggccgaa
    11101 gaaataaagc gacaccagaa aagccggaat cagtgcgatc agcacgccat acatattttt
    11161 ctgtacgctg tctccgccat gcacgtgggg tgatagtgat acgattaatt tattttccat
    11221 acttcgttat tttttagctt gacgtgcacg aatcatagct cctactttac ccttacccaa
    11281 gcggcagtaa tcaagcagcg gacggttggc aggacaagtg aactgacagg aaccgcactc
    11341 gatacaatcc atgattcttt ctttttccat tgtttcaaaa tctccgtttt cggacaaagc
    11401 tccgagcaag tacggctcca gtcccatcgg acaagcgctc acacactttg cgcaacggat
    11461 acaggtttgt gcttcaccac gtttggcttc cttctgattc ataatcagga taccggaact
    11521 gccttttgcg gtaggaactt cgatattcac cagagcctta cccatcatcg gaccgccacc
    11581 gatcactttt cccgtatcct ccggcagacc gccacaagca tcaatcagct gtttcatcgg
    11641 tgtaccgata cgcgccagga agttggaagg tttggccaca gacttgccag ttacggtaat
    11701 cacacgctca aacaacggtt tatttttctg aacagcttca taaacagcaa atgccgtacc
    11761 cacattctgc acaactgccc cagtagagat aggcagcgca ccacttgcca cctggcgttt
    11821 ggtaatcgca tcaatcaact gtttctcacc accctgagga tatttcactt tcaaaggaac
    11881 aacttcgatg cctgcataac tggaagcaac tttcgtcatc agttcaatag catccggctt
    11941 gttattctca attccgataa atgccttatt taccttcacg gctttcatca gaatggagac
    12001 acctaccatg acttcttccg cgtgttccag catcagctga tggtcggcag tcagatacgg
    12061 ttcacattcc accgcattga taatcacaca ttctgccttg aacgaaggag gcggacaaag
    12121 tttcacctgt gtagggaaac aagcaccacc caaacctacg ataccggcat cggcaatctt
    12181 cttcacgatt tcttcggacg aaagctcaca ttctttgacc agtgtcttgc tacggtcaat
    12241 ggtttcttcc cattcgtcgc cttctacatc aataaagata gcaggttttg cataaccgct
    12301 cgcatcgact actgtatcaa tcttcgccac ttttccactg acagaagagt gaattgctgc
    12361 cgaaacgaag ccggcaggtt cggcaatctt cgtgcctacc ttcaccatat caccttttgc
    12421 tactatcggt ttggcaggtg cgccaatgtg ctgccccaac agaataactg cctttgcagg
    12481 aacttccgct gtgatgatag gttgatgtgc cgacaattta ttttcgtgtg gatgaactcc
    12541 accaattgaa aatgtcttta acatacaatt ctgtatttta ttctgttatt attctgttac
    12601 cttcggagct tctgcagcaa ctgttttcgg tgcttcttcc gccttcggtt tacgtggagg
    12661 gaagttcagc tcgataatcg tgttctgcgg acaaacttcc acgcacttac ggcatgattt
    12721 acacttgttc ggatcgatgt aagccaggtt gttctccagc gtaatggctt cgaacggaca
    12781 agtcttgaca cacttaccac agccgataca gctcactgta caagccttac gtgctacggc
    12841 tcccttgtct ttgttcacac aagagatgta cacacggcgt gatttcttgc cttgcggacg
    12901 aatctcgatg atcgccttcg gacaagcctt cacacaagcg ccacaagctg tacatttggc
    12961 ttcatccact tccggaagtc ccgtttcagg attcatgtgg atagcgtcaa actggcaggc
    13021 agccacacag tcgccacatc cgaggcatcc gtagctacaa cctgtttctc caccatacaa
    13081 tgaagcggca atagcgcaac tcttcgcacc gtcgtattga ttaatacgcg gacgattggc
    13141 acagcttccg ttacatctta ctactgctac catcggttca gcttcagtag ctgccagtcc
    13201 gagaatatca gcaatttgtg ccatgacagg ctgaccgcct acagggcaga atttaccatc
    13261 cagcgaaccg gctttgacgc aagcatcggc aaatccgcta caaccaggat agccacatcc
    13321 accacagttt gcctggggca acacttcccc cacctgggca atccgcgggt cttcatacac
    13381 ggcaaatttc ttggaagcta cataaagaat agcggccagc acgagcgcta tagctcccaa
    13441 tgaaatcact gcaatcagaa tcaaattcat aatgttttag ttatttattg gttttatagt
    13501 aaatgaaaaa tgttgtttca ttcgcgtttt attgagccac aatacgaaat aataaggaat
    13561 aagaactgcc agagaaagaa gagccgcata cagttcattc cctatcaacg ccatccatgc
    13621 gaacagggaa acaatcagaa gtacaaaagg aattatgaat gcaagggtta cagccatcat
    13681 gcccatcgac gtttcgccga tcaccatcac ccgctctcct acctgatagg aagcagctgt
    13741 aacatccgtt atatctatga ctttgtcttt actatccgcc gaagaacagt ggccttttgc
    13801 gctacaagcc gcacaagccg acgtctgaac gattctcacc gacagatgag aaccctgtat
    13861 gttttccaca atacctagat gctttatagt attattcgtc attttgcaaa ctcaacatta
    13921 caaatcgcgg caaatttaat cattatttgt gaactacgaa gcattccctc atttttttct
    13981 acataataaa atgttatttt ttgtgttttc gttatcgcac acgaaaaagt aacgccaact
    14041 atttgatatt ttagcataca acaaagcagg cgggaaagtt cttcccgcct gcctgtctta
    14101 tctaaccaat tactttattt actgaatgct gcttacaatg atgcagcctg tactcccagt
    14161 actccggcaa tcgcaccggc tacagcaatg attactttca aaactacact ccaagttttc
    14221 ttcatagatt tttcctcctt tcttttttaa gcttttcaga ttatacagtc ggatccggag
    14281 cttcctcatc tcctcctcct tcatttccac caccgccatt ttcaccatca tccggatcat
    14341 tcggagtcac agaggcattc aacttcttca gatattcatc caaactgatc aaatccagtt
    14401 tttcatctgc acgggtagcc gtcttcgtga tacgcagttc cttattcgcc tgaaagaaga
    14461 tgcgcacgct atccacactt ttagcattga cgtctttcgc cgcatccgcc cctttcgagc
    14521 aggcagtcag cataaataca cccaagcctt cgatattcac agacttacct tccagaagtt
    14581 gctctttcat tttctccaca aaattctgaa tcacactctt gatatcaccg atggataaag
    14641 aagaatagcc ctgcattttc tgcgcaatat atttcagatt gacagactga cctaaagtga
    14701 tcagatgcgg ataatatttc ttgggagaat tgggaacacg cgggtcagat ggtcgcgtaa
    14761 caactttgta aattacactc ataatacgtt tttttaaaga ttcaaattca agttatttta
    14821 ttcacgtttt gttgatcaac aatgcaaagg tgaggctttt atttcagata acaaaaagaa
    14881 aagccccttg cggggctctt tttctgagaa aagttataat tcatagatat tcagatattt
    14941 atctttttgt atcttggcca tatccatagc cgtagccata acgtttgcca tagccgtaat
    15001 gcttgccata cttaccgtag ccgtagtaat aaccgtattt tcgcttcttc aggtctacac
    15061 cgttgatgac agtacaaaga ttaggcagct tcttctcaaa agacagttca ttgatcaatg
//
