LOCUS       c00172_gnlPro..         6695 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|EPMGIAPC_172.
ACCESSION   c00172_gnlPro..
VERSION     c00172_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 17:35:41
            Original ID  :: gnl|Prokka|EPMGIAPC_172
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 6695
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..1818
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 180.5; E-value:
                     1.9e-55)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg172_1"
                     /sec_met_domain="FAD_binding_2 (E-value: 1.9e-56, bitscore:
                     180.5, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 4.2e-38,
                     bitscore: 119.0, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LAGASAAASLGEMGFRVFNFCIQDSPRRAHSIAAQGGINAAKNYQ
                     NDGDSVYRLFYDTVKGGDYRAREANVYRLAEVSNNIIDQCVAQGVPFAREYGGTLDNRS
                     FGGAQVSRTFYAKGQTGQQLLLGAYSALSRQVNVGTVKLYTRYEMEDVVLIDGRARGII
                     AKNLVTGKLERFAAHAVVIATGGYGNAYFLSTNAMACNCSAAMACYRKGAWFANPAYVQ
                     IHPTCIPVHGDKQSKLTLMSESLRNDGRIWVPKKLEDAKKLQEGTLQGKDIPEEDRDYY
                     LERRYPAFGNLVPRDVASRAAKERCDKGFGVNNTGLAVFLDFSEAINRLGKDVVAQRYG
                     NLFDMYEEITDVSPYENPMMIYPAIHYTMGGIWVDYELMTSIKGLFAIGECNFSDHGAN
                     RLGASALMQGLADGYFVLPYTIQNYLADQITVPRFSTDLPEFAAAEKAVQEKIDWMMNI
                     KGKKSVDSIHKELGHIMWEYVGMGRTAEGLKEGLKKLKEVRKEFEKELFIPGDKEGMNV
                     ELDKAIRLYDFITMGELVAYDALNRNESCGGHFREEYQTEEGEAKRDDENYFYVACWEY
                     QGSDEKEPVLLKEPLVYEAIKVQTRNYKS"
     protocluster    1..6695
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[0:2607]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1..2607
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..6695
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..6695
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             1852..2607
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer4_7"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg172_2"
                     /sec_met_domain="Fer4_7 (E-value: 5.1e-13, bitscore: 38.3,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_3 (E-value: 1.6e-26, bitscore: 81.2,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.9e-07, bitscore: 20.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKNISFTLKVWRQKGPKAKGAFETYQMKDIPGDTSFLEMLDILN
                     EQLISEGKEPVVFDHDCREGICGMCSLYINGHPHGPATGATTCQIYMRRFNDGDTITVE
                     PWRSAGFPVIKDLMVDRTAYDKIMQAGGYVSVRTGAPQDANAILIPKPIADEAMDAASC
                     IGCGACVAACKNGSAMLFVSAKVSQLNLLPQGKPEALRRAKAMLSKMDELGFGNCTNTR
                     ACEAECPKNVSISNIARLNRDFIIAKLKD"
     CDS             complement(2746..3693)
                     /locus_tag="ctg172_3"
                     /transl_table=11
                     /translation="MKVFGECFFYEYYLSIFVTATNKQIYLPMPNSSACRGKKQCAQCP
                     KAVDNAIIYASHLRGFHLPARKCEENIIIFLLKGEVLVNSKEYAGTVLHAGEFILQAIG
                     SKYEILAMTDVECVCYRFSKPEFFCEDRYNHIMKEVTPPLIFYPLTITPELQLFLESSK
                     AYLSEEKICREMLCFKRKELAFILGNYYSDYELSMLIHPLAQYTNSFHYFVLQNHAKVK
                     TVEELAQLGGYTVATFRRIFNSVFHQPVYEWMMERRKESVVYELRYTDASISEICYKYG
                     FESLPHFSNFCKKNFGASPRSLRAGNLSEVNGMS"
     CDS             complement(3758..4726)
                     /locus_tag="ctg172_4"
                     /transl_table=11
                     /translation="MKKVLFLALAAAAVMSCSESEEIENAGQKAEIKLGTVVGNTTRAT
                     VTDLPELQKVGFTVYAYNTGATTMASVATFDAMKEFMAAVKVTYSAPDWSLTGETYYWP
                     MTDNLQFFAYGNPGTGALTYNQPAASAIYPSITYTVADVAAQTDLVAAKATDATKASNA
                     SGVSLKFGHILTQINFTVKAADALTYKLKTLTISGVHNKGTYGFDDSIWKSQEGTATYA
                     HTIDDGALEVNTTGVEVNTAWMLMPQTLDTNAKINVVYDIYEKDVLLDTVTSAIDLNDT
                     QAWGEGKKIRYTLTLANKAAKVTFVPEVGPWSTADDTNVEK"
     CDS             complement(4772..5776)
                     /locus_tag="ctg172_5"
                     /transl_table=11
                     /translation="VASNVGEMSGMKDARHMILWLFFGLLPMLGSCDFRDMLDDYPVSG
                     VQIKLDWKGVTDKLPQTMRIIFYPKDTQGRKVESYLPAGGGEVKVPPGKYAVVAYNFNT
                     ESIQIRGDESYETIEAFTGHCTGLDVHEDMVWSPDPLYVVALDEVEIRQSDVALPLDWK
                     PEAVVDHYSFDIKVEGWDRISSIICHVDGLNGSYFIGNRACHLSEVPICVDTKRENGLL
                     WGYFSSFVLLKDTKTRADSPMLLTLKIVKRDKTVQEVKVDITEVIETAPPSGGGEEEPD
                     VGVPGSEIHIEVPVPEDKVVVDDLEPGTDEGDGGIGGDVDDWDDETDVELPVN"
     CDS             complement(5752..6375)
                     /locus_tag="ctg172_6"
                     /transl_table=11
                     /translation="MGKRIFIYVFWLLLFCMMSGQVIGQNKSVESHSHTCKTVLALKNN
                     LLYDLALAPNIEVELPLGKRWSLNVEYKCPWWSDSGCNFCYQLLSGGTEARYWLGNRHT
                     RGRLSGHFLGAYAEGGTYDFQLKKEKGYRGKYYAAAGITYGYVRPLARHLAIEFSVGIG
                     YLDTEYRKYTSYGNDLVWVSSGKYHFIGPTKAKVSLVWLLTSGR"
ORIGIN
        1 cttgccggtg ccagtgctgc cgcctctctg ggcgaaatgg gtttcagagt attcaacttc
       61 tgcatccagg actctccgcg ccgtgcacac tccatcgctg cacaaggtgg tatcaatgct
      121 gctaagaatt accaaaacga cggtgactct gtataccgtc tgttctacga tacagtaaag
      181 ggtggcgact accgtgcccg cgaagccaac gtttaccgtc tggctgaagt atccaacaat
      241 attatcgacc aatgcgttgc acaaggtgtt cctttcgccc gcgaatacgg cggtacactg
      301 gacaaccgtt ctttcggtgg tgctcaggta tcccgtactt tctatgccaa gggtcagacc
      361 ggacagcagc tgttgctggg tgcatactct gcattgagcc gccaggtgaa cgtaggcact
      421 gtgaaactgt atacccgcta cgaaatggaa gacgttgtcc tcattgacgg acgtgcccgc
      481 ggtatcattg caaagaacct cgttaccggt aaattggaac gttttgccgc ccacgctgtg
      541 gtaatcgcta ccggtggtta cggcaatgcc tacttccttt ctaccaatgc aatggcatgt
      601 aactgctctg cagcaatggc ttgctaccgt aaaggtgcct ggtttgccaa ccctgcttac
      661 gtacagattc accccacttg tatcccggtt cacggtgaca agcagtctaa gctgactttg
      721 atgtccgaat ctctgcgtaa cgatggtcgt atctgggttc cgaagaagct ggaagatgcc
      781 aagaaactgc aggaaggtac actgcaagga aaagatattc ccgaggaaga ccgcgactac
      841 tacctggaac gccgttatcc ggcattcggt aacctcgttc cgcgtgacgt tgccagccgc
      901 gctgccaaag aacgctgcga caagggcttc ggcgtgaaca acaccggtct tgccgtattc
      961 cttgacttct ccgaagctat caaccgtctg ggtaaagatg tcgttgcaca acgttacggc
     1021 aacctcttcg atatgtatga agaaatcact gatgtcagcc catacgaaaa cccgatgatg
     1081 atttatccgg ctatccacta taccatgggt ggtatctggg ttgactacga actgatgacc
     1141 tccatcaagg gactgttcgc catcggtgaa tgtaacttct ccgaccacgg tgcaaaccgc
     1201 ctcggtgctt ccgccctgat gcaaggtctg gccgatggtt acttcgtatt gccttacact
     1261 atccagaact atctggccga ccagattaca gttccccgtt tctctaccga cctgcccgaa
     1321 tttgcagctg cagaaaaggc cgttcaggag aagattgact ggatgatgaa catcaagggt
     1381 aagaagtctg tagactctat ccacaaggaa ctgggccaca ttatgtggga atatgtaggt
     1441 atgggacgta cggccgaagg cttgaaggaa ggtctgaaga agctgaaaga agtccgcaag
     1501 gagttcgaga aagaactgtt catcccgggc gacaaggaag gtatgaatgt agaactcgac
     1561 aaggctatcc gtctgtacga cttcatcact atgggcgagc tggttgctta cgatgcactg
     1621 aaccgtaacg aaagctgcgg cggtcacttc cgtgaagaat atcagactga agaaggcgaa
     1681 gccaagcgtg acgatgaaaa ctacttctac gtggcttgct gggaatatca gggttctgac
     1741 gaaaaggaac cggtattgct gaaagagccg ctggtttacg aagcaatcaa ggtacagact
     1801 cgtaactaca aaagctaatc gggaagttga acatttaaag aattaaagaa aatggataaa
     1861 aatatatcat ttacgctcaa ggtatggcgc cagaagggtc cgaaagcaaa aggcgctttt
     1921 gaaacatacc aaatgaaaga tatcccgggc gatacttcat tcctcgaaat gctggatatc
     1981 ttgaacgaac agctgatttc tgaaggtaaa gaaccggttg tattcgacca cgactgccgc
     2041 gaaggtatct gcggtatgtg ttcgctctac atcaacggac acccccacgg tcctgcaacc
     2101 ggcgctacga cttgccagat ttatatgcgt cgtttcaacg acggcgatac catcactgtt
     2161 gaaccgtggc gctctgccgg tttcccggtt atcaaggact tgatggtcga ccgtacggcc
     2221 tacgacaaga ttatgcaggc aggcggctac gtcagcgtac gtaccggtgc tccccaggat
     2281 gccaacgcta tcctgattcc gaagcccatc gctgacgagg ctatggatgc tgccagctgt
     2341 atcggttgtg gtgcttgtgt ggctgcttgt aagaacggtt ctgctatgct gttcgtttct
     2401 gccaaggtga gccagctgaa cctgttgccc caaggcaaac cggaagcatt gcgccgtgcc
     2461 aaggctatgt tgagcaagat ggacgaactc ggtttcggta actgtacaaa cactcgtgcg
     2521 tgcgaagctg aatgcccgaa gaatgtttcc atcagcaaca ttgctcgcct gaaccgcgac
     2581 tttatcattg cgaaactgaa agactaatcc ggtctttctg caaataatat aggatgcgct
     2641 tcggataaac cttttgagca agctcagatt tatcactcag ctttcactat atttgattaa
     2701 tatcacaaga gactcctctg ccgggaaacc gccggaggag tttttttatg acatgccgtt
     2761 tacttcagat aaattgccgg cacgcaagct acggggagaa gccccgaaat tctttttgca
     2821 gaaattggaa aaatgaggca gcgattcaaa gccatattta tagcaaatct ctgatataga
     2881 agcatccgta taacgaagtt cataaaccac gctttccttc ctccgttcca tcatccactc
     2941 gtacaccggt tgatgaaaaa cagaattgaa tatacgccgg aaagtagcta ctgtatatcc
     3001 tcccaactgg gcaagttcct ctaccgtctt gactttggca tgattctgca agacaaagta
     3061 gtggaaggaa ttagtatact gggcaagagg atgtatcagc atggaaagct catagtcgga
     3121 gtagtaattt ccaagaatga aagcaagttc tttccgtttg aaacaaagca tttcccggca
     3181 aatcttctcc tcggacaaat aggccttgga actttccaga aagagctgca actcgggagt
     3241 aatggtcaaa ggatagaata tcaatggagg ggtaacctct ttcataatat ggttataccg
     3301 gtcctcacag aagaattcag gcttactgaa ccggtaacaa acgcattcca catccgtcat
     3361 ggcaagtatt tcgtacttgg aaccaatagc ttgaaggatg aactcacctg catgcaacac
     3421 agttcccgca tactccttac tgttgacaag cacttctcct ttcagcagga aaattataat
     3481 attttcctca cactttcgcg ccggcagatg gaatcctctg aggtgggaag catatattat
     3541 tgcattgtcc acagccttgg gacattgagc gcattgtttt ttacctctgc aagcagaaga
     3601 gttgggcatc ggcaagtaga tttgtttgtt tgttgcagtg acaaaaatag ataaataata
     3661 ctcataaaag aaacattccc cgaaaacttt cataaagaag tttcggggaa tgaataaaat
     3721 agaagtaatt cagtttttta ttgcggacag tgccgtttta tttttccacg ttcgtatcat
     3781 cagccgtact ccatggacca acttcaggta caaaggttac ttttgccgcc ttattggcca
     3841 gcgtcagcgt ataacgtatc tttttgcctt caccccaggc ttgtgtatca ttcaagtcaa
     3901 tggcggaagt tacagtatca agaagaacgt ctttctcata gatgtcatag acaacattga
     3961 ttttggcatt cgtatccaac gtctggggca tcaacatcca ggctgtattc acttccacac
     4021 ccgttgtatt cacttccaat gcaccatcgt caatcgtatg tgcataagtg gctgttcctt
     4081 cctgtgactt ccatattgaa tcatcaaaac cataagttcc tttattgtgc acaccggata
     4141 ttgtaagtgt tttcagttta taagtcaaag cgtcggctgc cttgacagtg aaatttattt
     4201 gggtcagtat atggccgaat ttcaaagata ccccactggc atttgatgcc ttggttgcat
     4261 ccgtcgcttt cgcggctacc aagtccgttt gggcagctac atccgctacc gtataagtaa
     4321 tggaaggata tatagcacta gcagccggtt gattgtacgt caaggccccg gtacccggat
     4381 tcccgtaagc aaagaactgc aagttatccg tcattggcca ataatatgtt tccccagtca
     4441 aactccagtc gggagcacta taagttacct taacagctgc catgaattcc ttcatcgcat
     4501 caaaagtcgc aacagaggcc attgttgttg ctcccgtatt ataagcatac acagtgaacc
     4561 ctaccttctg caattccggc aaatcagtca ctgtggctct cgtagtgtta cccactactg
     4621 ttcccaattt aatctccgcc ttttgtccgg cattctctat ctcctcactt tccgagcaac
     4681 tcattactgc tgctgcagcc aaagccaaaa ataaaacctt cttcataatt gtctgttatt
     4741 aaagttaata tatttatttg tctgtttgct atcaattcac cggtagctcc acatccgtct
     4801 catcatccca atcgtccaca tcgccaccaa tccctccatc tccttcatcg gttcccggtt
     4861 ccaaatcatc caccacaacc ttgtcctccg gtacgggaac ctcgatatgg atttccgacc
     4921 caggaacgcc cacatcaggt tcttcttcgc ctcctcccga gggaggagct gtttcaatca
     4981 cttccgtgat gtctaccttc acctcttgaa ccgttttatc tcgtttcaca atcttcagtg
     5041 tcagcaacat aggactatcc gcacgggtct tggtatcttt cagtaataca aaactggaga
     5101 aataccccca taaaagcccg ttttcacgct ttgtatccac acatataggt acctcgctca
     5161 aatggcaagc acggttgcct ataaagtaac ttccgttcaa gccgtccaca tggcagatga
     5221 tgctcgatat tctatcccat ccttccacct ttatatcaaa ggaataatgg tccactaccg
     5281 cttccggctt ccagtccaac ggaagcgcca catcactctg ccttatttcc acctcgtcca
     5341 aagccaccac atacaaaggg tcgggcgacc aaaccatatc ttcgtgtaca tccagccccg
     5401 tacagtgtcc cgtaaaagcc tcaatcgtct cataactctc gtcgccccgt atctgtatac
     5461 tctccgtatt gaagttatag gccaccaccg catacttccc cggcggtacc ttcacctcac
     5521 cccctccggc aggcagataa ctttcaacct ttctcccctg agtatctttc ggatagaaga
     5581 taatccgcat ggtctgcggc agcttatccg tcaccccttt ccaatccagt ttaatctgta
     5641 ctccgctaac gggataatca tccagcatat cgcggaagtc acagcttccc agcattggca
     5701 acagcccgaa gaacagccag agaatcatat gccgtgcatc tttcatacca ctcatctccc
     5761 cgacgttaga agccacacca aagaaacttt tgcttttgtc ggcccgataa agtgatactt
     5821 tccactgctg acccaaacca agtcatttcc ataagaagta tatttcctgt actccgtatc
     5881 caagtatcca atgcccacac tgaattcaat cgccagatgc cgagccagtg gacgcacgta
     5941 tccataagtt attcctgcag ctgcgtaata cttcccccgg tatcccttct cctttttcaa
     6001 ctgaaaatca taggtacctc cttcggcata tgctcccagg aagtgtccgg acaatcttcc
     6061 gcgcgtatgg cggtttccca accagtaacg cgcctctgtc cctcccgaaa ggagctgata
     6121 gcagaaatta catccgctgt cagaccacca agggcatttg tactcaacat tcaaagacca
     6181 cctctttccc aatggcagct ccacttctat gttcggagcc aaggccaggt cgtaaagcaa
     6241 attatttttt aacgccagca ccgttttaca agtatggcta tgggattcta ccgacttatt
     6301 ctgccctatt acctgccccg acatcatgca aaaaaggagt agccaaaaga catatataaa
     6361 aatgcgtttt cccataattt cgcgttgtat acaaacaaaa gtagaagata attaccgaat
     6421 aaaaatcact ttccatcact cttttcaaag gctgaaaggt tctgtgaaac gattgaaaca
     6481 gatttgcaac ttctgcctta tccgggacgc tgtgaataga ttcttctctc tcaaaaagtc
     6541 aatccgtgtg cgaaaacagt aaaattcagt gaaagaaata caaaagaagt agcaggaaca
     6601 ttctgaaatt tggaagataa caacgggaac cttacatttg taatgtgatt tttttcatag
     6661 tattagattt aaggttaaca aaggttggag tacag
//
