LOCUS       c00080_gnlPro..        14907 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|EFNNFLMH_80.
ACCESSION   c00080_gnlPro..
VERSION     c00080_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 17:48:48
            Original ID  :: gnl|Prokka|EFNNFLMH_80
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14907
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14907
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[7671:12732]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      7672..12732
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..14907
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14907
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             94..1161
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg80_1"
                     /sec_met_domain="Aminotran_5 (E-value: 5.9e-42, bitscore:
                     133.7, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKHNFYAGPSILSEYTIKNTAAAVENFAGMGLSLLEISHRSKEF
                     VAVNDEARALIKELLDVPAGYEVVFMGGGASMQFCMVPYNLLNKKASYLDTGTWASNAI
                     KEAKLFGEVDVVASSKDKNYTYIPKGYAIADDSDYFHFTSNNTIYGTEMRKDPDVKQRL
                     VCDMSSDIFSRPIDISKYDIIYAGAQKNLAPAGVTLAIVRVDALGHVDRPIPTMLNYAT
                     HIKKDSMFNTPPVLPIYAALQTLKWYKEQGGIAAMEKKDLENAAILYDEIDRNKLFRGT
                     VAEEDRSIMNVCFVMNDEYKELEDEFSKYATAAGMVGIKGHRSVGGFRASLYNAMPKSS
                     VEALVACMKEFEKQH"
     CDS             1179..2102
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Hacid_dh_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg80_2"
                     /sec_met_domain="Hacid_dh_C (E-value: 2.6e-36, bitscore:
                     114.5, seeds: 144, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKILVATEKPFAAVAVKGIREVVEGAGMELALLEKYTEKAQLLD
                     AVKDADAVIIRSDKVDAEVLDAAKNLKIVVRAGAGYDNVDLDAATAHKVCVMNTPGQNS
                     NAVAELVFGMLVYGVRNFYNGTSGTELKGKKLGILAYGNVGRNVARIAKGFGMEVYAYD
                     AFCPASVIEADGVKAVASTADLFKACQIVSLHIPATAETKGSINFELMNSMPKGAIVVN
                     TARKEVMDEAGLAKMLEERPDFKYLTDIMPAIHAELAEKYAGRYFSTPKKMGAQTAEAN
                     INAGIAAAKQIVDFLVNGNEKYRVNK"
     CDS             2115..3362
                     /locus_tag="ctg80_3"
                     /transl_table=11
                     /translation="MAKIKPFKGVRPPKEFIEEVASRPYDVLNSQEARVEAEGNEKSLY
                     HIIKPEIDFPEGTDEHDPAVYLKAAANFNNFQEKGWLVQDQKECYYVYAQTMNGKTQYG
                     LVVGAYVPDYMNGTIKKHELTRRDKEEDRMKHVRVNNANIEPVFFAYPDNSELDAIVMK
                     YTAREPEYNFVAKLDGFGHTFWIIDEDKDIARITELFGEMPALYIADGHHRSAAAALVG
                     AEKAKQNPDHKGDEEYNYFMAVCFPANQLTIIDYNRVVKDLNGLTEEQFVERLTKNFVV
                     EEKGSAIYKPGALHNFSLYLGGKWYSLTAKPGTYDDNDPIGVLDVTISSNLILDEILGI
                     KDLRSDKRIDFVGGIRGLGELKRRVDSGEMKVALALYPVTMKQLMDIADTGNIMPPKTT
                     WFEPKLRSGLVIHKLD"
     CDS             3485..4117
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg80_4"
                     /sec_met_domain="HAD_2 (E-value: 4.8e-10, bitscore: 29.7,
                     seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGKIKNIVFDLGGVIIDLDRDEPVRRLIEIGVKDADGLIDPYEQK
                     GVFQDLETGKIGVEEFCRYLRKYTGKDLSYEDICWAWFGFIGGVPQYKLDYILKLREKY
                     QVYLLSNTNPIIQLEWAQTKEFTPAGRPLNDYFDKLYLSYEIGVTKPDREIFDRMILDS
                     GIKPEETLFVDDGKNNIVVGQELGFHTYQPLNGEDWRGRLDEILSKS"
     CDS             4156..6537
                     /locus_tag="ctg80_5"
                     /transl_table=11
                     /translation="MTNTTLNLEELLCGVNELVDTLWIVTLGNEKVEIVKDSMTPEREG
                     ECLDYTELCQTYIQEYVYPADLGKWEEILSLNSLRQMAASGVANKKFDMRFCNDLFGFE
                     WHEAFIRILKDKSGIPDRVILFSRYVNHCRKAQIVEAAVQTEYDYVVYIEANTNSYVMY
                     TSNRESGTPVPPIASNDYEKEVAEFHHKYVPEDQRDELTRNLSLDHVLSILQNSREYVL
                     FCQVMENGVFRDKKLRFSFFDKERNILLLTRTDIMEVREEERQRQLLQDALQVAKSANQ
                     AKSDFLSRMSHDIRTPMNAIIGMTTIASMHIDDRERIVDCLKKIMVSSKLLLNLINEVL
                     DMSKVESGHILLTDEEFDMGELLQSVITMVQTSVSQKFQDFRVHLFQIKHEKLIGDVQR
                     IQQVLLNLLSNAIKYTPDYGKITLEIREKPIKNGNYGLFEVTVIDNGIGIKPDFLHKVF
                     EPFERAEDATLRNIQGTGLGMAISRNIAHMMNGEILVESEYGKGSVFTFTMQLKLQDQG
                     CFEDDHLRDLPVLVVDDDIVCCENACMRINEIGMKGEYAISGEEAIGKVERAHHLNDDY
                     FAVILDLKMPGMDGIETATRIRKVVGRDIPIIILSAYDCPHFEEIAQRAGVDGFISKPL
                     MKSKLFYLMKSFAIKQEEKEEETEKPQYPFGNFEGKRILLVEDNSLNREIATVLLEETG
                     AVVEEAENGLVAVNMVKNSSPGYYDLVFMDIQMPVMNGYDSTRHIRALERPDIKSMPII
                     AMSANAFAEDIKLCKESGMNEHIAKPIDFGKVLEILEKYL"
     CDS             complement(6606..7646)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GDP_Man_Dehyd"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg80_6"
                     /sec_met_domain="GDP_Man_Dehyd (E-value: 9.2e-50, bitscore:
                     159.7, seeds: 258, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKKILVAGGTGYIGSHTTVELQNAGYEVVIIDDLSNSNIEVLDG
                     IEKITGIRPEFIQLDLKDKEGTRKALEAHPGIKGIILFAASKAVGESVQQPLKYYRNNI
                     VTLVNLLEMMPEFNIEGIVFSSSCTVYGQPDPENLPVTENAPIKPAMSPYGNTKQINEE
                     IIRDTIHAGAPFKSIILRYFNPIGAHPSAEIGELPNGVPQNLIPYLTQTAMGIRKELSV
                     FGDDYDTADGSCIRDYINVVDLAKAHVIAMDRMLENKSDEHIEIFNLGTGNGVSVLELI
                     NTFEQTTGVKVPHKIVGRREGDIEKVWANPEHANKVLGWTAKETLADTLQSAWNWQKRL
                     RERGIQ"
     CDS             complement(7672..8244)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg80_7"
                     /sec_met_domain="Rnf-Nqr (E-value: 1e-65, bitscore: 210.9,
                     seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYILIFIAAVFVNNVVLAQFLGICPFLGVSKKVETAAGMGAAVT
                     FVLTIATIVTFLVQKYILDAFGLGFMQTISFILIIAALVQMVEIILKKVSPALYQALGV
                     FLPLITTNCCILGVAILVIQKEYNLLESVVYAISTAIGFALALIIFAGIREQLAMTHVP
                     EGMKGTPIALITAGLLAMAFMGFSGIV"
     CDS             complement(8257..8841)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg80_8"
                     /sec_met_domain="Rnf-Nqr (E-value: 6.4e-69, bitscore:
                     221.3, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNLKILMNGIITENPTFVLLLGMCPTLGTTSSAINGMSMGLATM
                     FVLICSNIVISALKNVIPDLVRIPGYIVVIATFVTVVQMCMEAFVPALYASLGLFIPLI
                     VVNCIVLGRAEAFAAKNGVIPSAFDGIGIGLGFTMALTLLGACREFLGTGKLFNVTLMP
                     EEYGSLIFVLAPGAFIALGYLVAIVNKLRKA"
     CDS             complement(8859..9443)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FMN_bind"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg80_9"
                     /sec_met_domain="FMN_bind (E-value: 5e-26, bitscore: 81.1,
                     seeds: 891, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLSLTGICLVAGAILAGVNQFTAGPIAVAKATALEEAIKAVAPE
                     FDNKPTEDAYMAVSSDGDSLKIYPAKKGGQVVGGAVESNTKKGFSGEIRVIVGFDMDGK
                     ILNYSVLQHAETPGLGAKMQEWFRADKNKQSVLGRTIPDGGLKVTKDGGDVDAITAATI
                     SSRAFLDAVNRAYSAFAGVDGLTGATSTDNK"
     CDS             complement(9476..10444)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg80_10"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 6.7e-117,
                     bitscore: 379.8, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENNLYVSPSPHIHGGDSISKNMYGVLIALIPAFLVSLYFFGLGA
                     LIVTVVSVLACMIFEYLIQRFLMKKEPTLCDGSAILTGVLLAFNLPSNLPVWIIIIGAL
                     AAIGIGKMSFGGLGNNIFNPALVGRVFLLISFPAQMTTWPVVDALNVFPMTYTDAQTGA
                     TVLSLMNEGVTELPSYGNMLVGAMGGSLGEVSAVALILGLLFMLWKKIITWQIPVSILA
                     TVFVFTGIMHLVNPVQYASPFVHLLSGGLLLGSIFMATDYVTSPMSKNGMLVYGVGIGI
                     LTTVIRLFGSYPEGMSFAILIMNAFTPLINSYIKPKHFGGK"
     CDS             complement(10457..11788)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_10"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg80_11"
                     /sec_met_domain="Fer4_10 (E-value: 9.1e-10, bitscore: 28.6,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 3.3e-17, bitscore: 52.1,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 1.5e-50, bitscore:
                     161.0, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 2.9e-32, bitscore: 100.7,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.8e-05, bitscore: 15.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLRTFRIGGIHPPENKLSAGKKITALATPKQVIIPLSQHIGAPAQ
                     AVVKKGDLVKVGTLLAKAGGFVSANIHSSVSGKVNKIDNALDASGYKRPAIYIDVEGDE
                     WEETIDRSETLVKECSLSSKEIVDKIAASGIVGLGGATFPTQVKLMPPPGNKAEIVIIN
                     AVECEPYLTSDHSLMLEKGEQILVGVTILMKAVNVNKAVIGIENNKPDAIAHLQKLAVN
                     YKGIEIMPLKVQYPQGGEKQLIDAVIRRQVKSGALPISAGAVVQNVGTAYAVYEAVQKN
                     KPLFERVVTITGKAVANPSNFLVRMGTPISCLIEAAGGLPENTGKIIGGGPMMGKALIS
                     AEVPVCKGSSGVLLLTKEESVRKPIRDCIRCAKCVGVCPMGLNPTLLMNATEFQNWELA
                     EKNYITDCIECGSCSYTCPANRPLLDQIRLGKGKVMGIIRSRKS"
     CDS             complement(11800..12732)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FeS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1016:4Fe-4S dicluster domain (Score: 36; E-value:
                     2.7e-11)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg80_12"
                     /sec_met_domain="Fer4_7 (E-value: 6.2e-12, bitscore: 36.0,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 1.1e-11, bitscore: 34.2,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 2.2e-09, bitscore: 27.1,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="FeS (E-value: 1.6e-10, bitscore: 30.5,
                     seeds: 364, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.2e-06, bitscore: 18.8,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MILIAVISLGAIGAVGAVFLYAASKKFEVYEDPRIAQVQEVLPGA
                     NCGGCGYPGCAGFAGACVKADSLDGLLCPVGGGPVMAKVATILGKEAGTAEPMVAVVRC
                     NGTCQARPRTNSYDGTKSCAIASTLYGGETNCSFGCLGYGDCVNACAFDAIHINPATGI
                     AEVDEEKCTSCGACVKACPKNIIELRKKGPKSRRIYVSCVNKDKGAAARKACANACIGC
                     GKCAKECPFEAITVTNNVAYIDYTKCRLCRKCVAVCPTGAIHELNFPPRKEAAPAPKAE
                     TVKPVPKAEATVKPEATPKATSEEKTNLN"
     CDS             complement(12742..13158)
                     /locus_tag="ctg80_13"
                     /transl_table=11
                     /translation="MSESINHTGFVEKIDGDTVFVRITQQSACSGCHAQSMCSASEKKD
                     KIIEVPDRSGRFCVNEEVIICGQNSMGLQAVLLAFVIPLVIVVGAIVIGTNLQWDETTS
                     GLTGLSLLLPYYCILYLMRDKLKRRFIFTLKKLN"
     CDS             complement(13260..14801)
                     /locus_tag="ctg80_14"
                     /transl_table=11
                     /translation="MMKRHGVYALLLLSLIGSSAYSQENQLVTGTIVQRPAQQVVSDDT
                     IPAINLGEEELDNIVDIRKQFEKQNKTYSAPLAPSTNLLRFLKKDELEISDEAMYWARL
                     VRDASTAFDNTMTFRDTVIVNPLFMPIVFRGDYLPKNLIFYNFDSLKERTPYDNLYRTD
                     SIFKDLERNKQFEEMAYKYVQNNYPTYFRYSERDLPNEVIKPKFIKKNIYEDLPIKVEA
                     DANFEDVDAPARFIPERRYWISAFESAVQFSQNYVSENWYKGGSSNLNLFTKNNLKYDY
                     KKDKVQVTNELEFKASVYTAPKDTLRNYKIGDDVFRIHSNVGYQAFNKWYYTFDAEFKT
                     QFFTNYQENEHIKQAAFLAPFSINFGLGMKYELEKQFTDKHKKVKFSTNLAPISYTYMY
                     TTQEIDYSRHGFKKNEETGEFNNKLSQIGSTIRADLAFDFNRNVSWQSRLYFFTTYGDH
                     TIGEFENTLVLAISRFFSTRIYFHLRYDDGVEKTEDNKSYFQLNELLSFGFNYKW"
ORIGIN
        1 gtgtcggcaa atgagaaaaa atagttacat tagccgcctg tttttgaaaa aatagttact
       61 ttatttataa taacattcta aaaagacatt ggtatgaaga agcacaattt ttatgcaggt
      121 ccttctatct tgagcgagta tacaattaag aatacagccg ctgcggtaga aaattttgcg
      181 ggtatggggt tatcacttct tgagatctct catagaagta aggagtttgt agccgtaaac
      241 gacgaggcac gtgcgttgat caaggaatta ctggatgttc cggcaggcta tgaggttgta
      301 ttcatgggcg gtggcgccag catgcagttc tgtatggttc cttacaatct gttgaataag
      361 aaagcctctt atttggatac cggcacatgg gcttcgaacg ctatcaagga agctaagttg
      421 tttggggagg tagatgttgt cgcttcttcc aaagacaaga actatactta catcccgaag
      481 ggttatgcta tcgctgatga ctcggattat ttccatttta cttctaataa tacgatttac
      541 ggaacagaga tgcgtaagga tccggatgtg aagcaacgtt tggtttgcga tatgtcttcc
      601 gatattttct ctcgtccgat cgatatttcc aaatatgata ttatctatgc gggtgctcaa
      661 aagaacttgg ctcctgccgg cgtgactttg gctatcgttc gtgtggacgc tttaggacat
      721 gtagaccgtc cgatcccgac catgttgaac tacgctaccc atattaaaaa ggattccatg
      781 ttcaatacac ctcctgtatt gcctatttac gcggctttac agaccttgaa atggtataag
      841 gaacaaggtg gtatcgccgc tatggagaag aaggatcttg agaacgcggc gatcttatac
      901 gatgagatcg atcgcaataa gttgttccgt ggtacggtag cggaggaaga tcgttcgatc
      961 atgaatgttt gtttcgtgat gaatgatgag tataaggagt tggaggacga gttcagtaaa
     1021 tatgctactg ccgctggtat ggtaggtatc aagggacacc gttctgtagg tggtttccgt
     1081 gcctctcttt ataacgcgat gccgaagagc agcgtggagg ctttggtagc ttgcatgaaa
     1141 gagttcgaga aacaacatta attaaggagg attcagacat ggcaaagata ttagttgcta
     1201 cagagaaacc tttcgccgct gtcgctgtga aaggcatccg ggaggtagtg gaaggcgctg
     1261 gcatggaact ggctcttttg gagaaatata cagagaaggc gcaattgctg gatgcggtta
     1321 aggatgccga tgccgtgatt atccgtagcg ataaggtgga cgctgaggta ttggatgccg
     1381 ctaagaacct gaagatcgtg gttcgtgccg gtgcggggta tgataacgtg gacttggatg
     1441 cggctactgc ccataaggta tgcgtgatga atacgccggg acaaaactct aacgctgtcg
     1501 ccgaattggt attcggtatg ttggtgtacg gggttcgtaa tttctataac ggtacttccg
     1561 gaacagagtt gaaaggaaag aaattgggta tcttggctta tggaaacgtg ggccgtaacg
     1621 tggctcgtat cgctaaaggc ttcggtatgg aggtttacgc ttacgatgcg ttctgtccgg
     1681 cttccgtgat tgaggccgat ggtgtgaagg ctgtagcttc tacagccgat ttgtttaagg
     1741 cttgccaaat cgtctctttg catattccgg ctacggccga gacgaagggt tctatcaatt
     1801 tcgagttgat gaattccatg ccgaagggag ctatcgtagt gaatacggct cgtaaggagg
     1861 tgatggatga ggctggactc gctaagatgt tagaagagcg tccggacttc aagtacttga
     1921 cagatattat gcccgctatc catgcggaat tggccgagaa atatgccggt cgttatttca
     1981 gcaccccgaa aaagatgggt gcccagaccg ccgaggctaa tatcaacgct ggtatcgccg
     2041 ccgccaagca gatcgttgat ttcttggtga atggcaatga aaagtatcgg gttaataaat
     2101 aatatttaat taccatggca aaaataaaac ctttcaaggg agttcgtccg ccaaaagaat
     2161 ttatagagga ggtggcttcc cgtccctatg acgtattgaa ctcgcaagaa gctcgtgtgg
     2221 aagcggaagg aaacgagaaa tccctttacc atatcattaa accggaaatc gatttcccag
     2281 aagggacgga tgagcatgat ccggctgttt acctgaaggc cgccgccaat ttcaataatt
     2341 ttcaggaaaa aggttggttg gttcaggatc agaaagaatg ctattatgtt tatgcccaaa
     2401 ccatgaatgg caagactcaa tatgggttgg tagtcggggc ttatgttccc gattatatga
     2461 atggcacgat caagaaacat gagctgaccc gccgtgacaa ggaggaggat cgcatgaaac
     2521 acgtacgtgt caacaacgct aatatcgagc cggtattctt cgcttatccc gacaactcag
     2581 agctagacgc tatcgttatg aaatatacgg ctcgtgagcc cgaatataat ttcgtggcga
     2641 aattagacgg tttcggtcat acgttctgga ttatcgatga ggataaggat atcgctcgca
     2701 tcacggagtt attcggggag atgcctgcgt tgtatattgc cgacggacat catcgttccg
     2761 ccgccgctgc tttggtagga gcggagaagg ccaagcaaaa cccggatcat aagggagacg
     2821 aggagtataa ctatttcatg gctgtttgct tcccggccaa ccaattgacc attatcgatt
     2881 acaaccgtgt ggtaaaagac ttgaacggct tgaccgagga acaattcgtt gagagattaa
     2941 cgaaaaactt cgtggtagag gagaagggct ctgctattta caaaccgggt gccttgcaca
     3001 atttctccct gtatttagga gggaaatggt attctttgac tgctaagccc ggtacgtacg
     3061 atgataatga cccgataggc gtattggatg tcacgatctc ttcgaacttg attctggatg
     3121 agattttagg cattaaggat ttacgttcgg acaagcgaat cgatttcgtg ggaggtatcc
     3181 gtggcctggg tgaattgaaa cgccgtgtgg atagcggtga gatgaaggtt gccttggctt
     3241 tgtatcccgt tacgatgaag caattgatgg atatcgccga tacgggtaat atcatgccgc
     3301 cgaagacgac gtggttcgaa ccgaagcttc gctccggttt ggtgatccat aaattggatt
     3361 aagtgttata tacataaata tagctttgga ttggggtata atcgttgaag attataccct
     3421 tttttatctt tgtaacctag atatacggaa taaattgtat ctttgggact taaatagtat
     3481 cgcaatgggt aaaataaaaa atatagtatt cgatctgggg ggcgttatca tagatttgga
     3541 ccgggatgaa cctgttcgcc gtttaataga gattggggtc aaagatgccg atggattgat
     3601 agatccttac gaacaaaaag gggtttttca agatctggag accggaaaga tcggagtaga
     3661 ggagttttgt cgctatttac ggaagtatac gggtaaagac ctttcttatg aggatatttg
     3721 ttgggcttgg tttggcttca ttggcggcgt tccccaatat aaattggact acatattaaa
     3781 actccgtgag aaatatcaag tctatttatt gagcaataca aatccgatca tacagcttga
     3841 atgggcacag acaaaagagt ttacgccggc gggccgtcca ttaaatgatt atttcgataa
     3901 attgtatctc tcttatgaga tcggtgtcac gaagccggat cgtgaaattt ttgatcgcat
     3961 gatcttggat tcaggaatca aaccagagga aacattattt gtagatgatg gtaagaataa
     4021 tatcgtagtg gggcaggaac tagggttcca tacctatcag cctttgaatg gagaggattg
     4081 gagagggagg ctcgatgaaa tactctcaaa atcataggat ctctattcct cttaattaaa
     4141 tctatatcat tgaaaatgac aaatactact ttaaatttgg aagaactact ctgtggtgta
     4201 aacgagctag tcgatacgct ttggatcgtc acattaggta atgaaaaggt tgagatagtc
     4261 aaagattcga tgactcccga aagggaagga gaatgtttgg attatacgga actttgccag
     4321 acttacattc aagaatatgt atatcctgcg gatttaggga aatgggagga gatcttatcc
     4381 ttgaattcat tgcggcaaat ggcggctagc ggcgtagcga ataagaagtt cgacatgcgt
     4441 ttctgtaatg atttgtttgg ttttgagtgg catgaggctt ttattcgtat cttgaaagat
     4501 aagagtggaa ttccggatcg tgtcattctt ttcagccgct atgtgaatca ttgtcgcaag
     4561 gcacagatcg tagaggctgc cgttcagact gagtatgatt atgtcgttta tatagaggca
     4621 aatacgaata gctatgtcat gtatacttcc aatcgtgaaa gtgggacgcc ggtccccccg
     4681 atagcgagta atgactatga aaaagaggta gccgagttcc accacaaata tgtgccggag
     4741 gatcagcgag atgagttaac ccgaaatctt tccctagatc atgtcttatc tatcttacaa
     4801 aattcccgtg agtatgtctt gttctgtcag gtgatggaga atggcgtttt tagggataag
     4861 aagttgcgtt ttagcttttt cgataaggag aggaatatac ttcttttgac ccggaccgat
     4921 attatggagg ttcgtgagga agagcggcaa aggcaattac ttcaagatgc cctacaagtg
     4981 gctaaatcgg caaatcaggc taaatcggat ttcttatccc gtatgagcca tgatatacgt
     5041 actccgatga atgccattat cggtatgacc actatcgcca gtatgcatat cgacgatcgg
     5101 gagcgtatag tggattgctt gaagaagatt atggtttctt ccaaattgtt attgaacttg
     5161 atcaatgagg tcttggatat gtctaaggta gagagcggac atattttgct gacagacgag
     5221 gagttcgata tgggcgagtt attgcaaagc gtaattacta tggttcagac ttcggtcagt
     5281 cagaagtttc aggatttccg ggttcacttg tttcaaatca aacatgaaaa gctgattggc
     5341 gatgtgcaac ggattcagca agtattgttg aatttgctgt caaacgccat aaagtatacg
     5401 ccggactatg ggaaaataac acttgagata cgggaaaagc caattaaaaa tggtaattat
     5461 ggtttatttg aggttacggt tatagacaat ggtatcggga taaagccgga tttcttacac
     5521 aaggttttcg aaccatttga acgtgcggaa gacgcaacct tgcggaatat acaaggaacc
     5581 ggcttaggca tggcgataag ccgtaatatc gctcatatga tgaatggtga gattctggtg
     5641 gagagtgaat atggcaaagg ttccgttttt acatttacga tgcagttgaa attgcaggat
     5701 caagggtgtt ttgaggatga tcatttaagg gatttaccgg ttctcgtggt agacgatgat
     5761 atcgtgtgtt gcgagaacgc atgtatgagg attaacgaga tcggtatgaa aggtgaatat
     5821 gccatttctg gtgaggaggc tatcgggaaa gtagagaggg cacatcatct taatgatgac
     5881 tattttgccg ttatccttga tctgaaaatg ccgggaatgg atggaatcga gaccgctacc
     5941 cgtatccgaa aagtcgttgg ccgggatatt ccgatcatta ttctttccgc ttatgattgt
     6001 ccgcattttg aggagatagc ccaacgagcc ggtgtcgatg gattcataag taagccgttg
     6061 atgaaatcca agttatttta tttgatgaaa agtttcgcta tcaagcaaga ggaaaaagag
     6121 gaagagacgg agaagcctca atatcctttc ggtaactttg agggtaagcg gatcttgctg
     6181 gtggaagata atagcttgaa tagggaaata gcgactgtgt tactagaaga gaccggtgcg
     6241 gtggtagagg aggcggaaaa tggccttgtc gcggtgaata tggtaaaaaa ctctagtccg
     6301 ggatattatg acttggtatt tatggatatc cagatgccgg tcatgaacgg gtacgactct
     6361 actcgccata ttcgggcatt agaacgtccg gatatcaagt ccatgccgat aatagccatg
     6421 tctgcgaacg catttgcgga agacatcaag ttgtgtaaag aatccggaat gaatgagcat
     6481 atcgctaagc cgatcgattt cgggaaagtt cttgagatct tagagaaata cttgtagata
     6541 taaggatata aaaaaggcca tatcttagct aagtgctatc agatacggcc tcttttttgt
     6601 gttatttact ggatgccacg ttctctcaaa cgtttctgcc agttccatgc ggattgcagg
     6661 gtgtcggcta aagtctcctt ggcggtccag cctaatacct tattcgcgtg ctccggattg
     6721 gcccatacct tctcgatatc accttcacga cggcccacga tcttgtgcgg aaccttaacg
     6781 cctgttgtct gctcgaaggt attgatcagt tcaaggacag aaacaccatt gccggtacct
     6841 aggttgaata tctcgatatg ctcatcagac ttattctcaa gcatacggtc catagcgatt
     6901 acatgcgctt tcgccaagtc tacgacattg atatagtcac ggatgcaaga gccgtctgcc
     6961 gtatcataat catcgccgaa tacgcttaat tccttgcgga tacccatagc cgtctgtgtc
     7021 aagtacggga tcaagttctg gggaacacca tttggcaact cgccgatctc tgcgcttggg
     7081 tgagcgccta tcgggttgaa gtagcgcaag atgatactct tgaaaggcgc tcccgcatgg
     7141 atcgtatccc ggataatctc ctcgttgatc tgcttcgtgt ttccataagg agacatagcg
     7201 ggtttgatcg gggcattctc ggttaccggc aagttctccg gatccggttg tccgtatacc
     7261 gtacaagagg aagagaatac gataccttcg atattgaatt caggcatcat ctccaacaag
     7321 ttcaccaaag tgacaatatt attgcgataa tacttcaaag gctgctgtac ggattctcct
     7381 accgccttgc tagcggcgaa caagataatg cctttgatgc ccggatgagc ttccaatgcc
     7441 ttgcgagtac cttccttatc ctttagatcc aattggataa actccggacg gatgcccgtg
     7501 attttctcga taccatcgag cacctcgata ttcgagtttg acaaatcgtc gataatgact
     7561 acctcatatc cggcgttctg caattctact gtggtgtgtg agccgatata accggttccg
     7621 cccgctacta aaatcttctt tttcattcta gtgttcattt agataagttt gttatacgat
     7681 acccgagaat cccataaaag ccatagctag caaaccggcc gttatcaagg cgataggagt
     7741 gcctttcatg ccttccggaa catgcgtcat ggctagttgc tcccgaatac ccgcgaagat
     7801 aatcaaagct agcgcaaatc caatagcggt cgagatagca tataccacag attctaataa
     7861 attatactct ttttggatta caaggatcgc cacacccaag atacagcagt tcgtggtgat
     7921 caacggaagg aatacgccca acgcctggta aagggcggga gagaccttct tcaatatgat
     7981 ttccaccatc tgaaccaagg cggcgatgat caagatgaaa ctgatcgtct gcatgaaccc
     8041 taatccgaaa gcgtccaata tgtatttttg cacgaggaat gtaacaatcg tagcgatcgt
     8101 aagaacgaac gtaacggcgg ctcccatgcc tgcggcagtc tccactttct tagatacccc
     8161 caagaacgga caaattccca agaactgtgc cagtacaacg ttattaacga atacggcggc
     8221 gataaatatc aatatatatt ccatatgatc cgtttattat gctttacgca gtttgtttac
     8281 tattgctacc agataaccca aggcgataaa cgctcccgga gccaatacga agatcagcga
     8341 accgtattcc tcgggcatca aggttacgtt gaataactta ccggttccca agaactcacg
     8401 gcaagcgccc agcagcgtaa gagccatcgt gaagcccagt ccgataccga ttccgtcgaa
     8461 agcggatggg attacgccgt tcttcgcggc gaaagcctcg gcacgtccta gtacgataca
     8521 gtttaccacg atcaacggga taaataatcc taagctagcg tataaagccg gaacgaatgc
     8581 ttccatgcac atctgcacta cggtcacgaa cgtcgcgatc acaacgatat atcccgggat
     8641 acgcaccaag tcggggatta cgtttttcaa ggcggagatc acgatattcg agcaaatcaa
     8701 tacgaacatc gtagccaatc ccatactcat gccgttgatg gccgaagagg tcgttcccaa
     8761 ggtaggacac atacctaaca gtaatacaaa tgtcgggttc tccgtgatga taccattcat
     8821 caatattttt agattactca ttgctctgtc ctcccttttt atttgttatc agttgaagtg
     8881 gcacccgtta atccgtctac gcctgcgaat gcgctatacg cacggttcac ggcatcgagg
     8941 aacgcacggc tggagatggt cgcagccgtg atagcgtcca cgtcgccacc atcttttgtt
     9001 acttttaaac ctccgtccgg aatcgtacgt cccaagacac tttgcttatt cttgtccgca
     9061 cggaaccatt cttgcatctt ggctcccaag cccggagtct cggcgtgttg caatacggaa
     9121 tagttcaaga tcttgccatc catatcgaaa cctacgataa cccgtatctc accgctaaag
     9181 ccttttttcg tattactctc tacggctccg ccaacgactt gtccgccttt cttggcagga
     9241 taaatcttga gggaatcacc atcggaggag actgccatat aagcgtcctc ggtcggtttg
     9301 ttgtcgaact cgggagcaac ggctttaatc gcttcctcca aggcggtcgc tttagctacc
     9361 gctatagggc cggcggtaaa ctggttcact ccggctagga tcgcccctgc taccaagcaa
     9421 atgcctgtta gtgaaaggag catattgggt aatgttgatt ttaattttgc catgcttact
     9481 ttcctccgaa atgtttaggt ttgatatagc tgttgattag cggagtaaat gcgttcatga
     9541 tcaggatagc gaacgacata ccttccgggt aagacccgaa caaacggatc accgtggtaa
     9601 ggattccgat tcccacgccg tagacaagca ttccgttctt gctcatcggc gaggttacgt
     9661 agtcggtcgc cataaagatg gagcctaata acaaaccgcc ggataataag tgaacgaacg
     9721 ggctggcgta ttgtaccgga ttcaccaagt gcatgatgcc cgtgaatacg aatacggtag
     9781 ccaagatgga taccgggatc tgccaagtga tgatcttttt ccatagcatg aataaaagac
     9841 cgaggatcaa ggccacggcg ctcacttcac cgagactacc tcccatagct cctacaagca
     9901 tgttcccgta agacggaagc tcggtcacgc cttcgttcat caacgacaat accgttgcgc
     9961 cggtctgggc atccgtataa gtcatcggga aaacgttcaa ggcatctacc accggccaag
    10021 tcgtcatctg tgccgggaag gagatcaata agaatacacg tccgactaac gccggattga
    10081 aaatattatt acctaatcca ccgaaagaca tcttgccgat gccgatcgct gccaacgctc
    10141 cgataataat gatccagacc ggaaggttgg aaggtaggtt gaaggccagc aatacacccg
    10201 tcaggatagc ggagccatcg caaagggtcg gttccttttt catcaggaat cgctggatca
    10261 aatactcgaa tatcatacag gccagaaccg atacgaccgt aacgatcaac gctcccagac
    10321 cgaagaaata aagggatacc aagaaagccg ggataagggc aatcagtaca ccatacatat
    10381 ttttgcttat gctgtcgcca ccatggatgt ggggcgaggg cgatacgtat aaattatttt
    10441 ccatgttgct cttgttttat gactttctag accggataat acccataact tttcctttac
    10501 ccaaccggat ctgatccagc aacggacggt tggccggaca ggtataacta cacgacccgc
    10561 actcgataca gtcggtgata tagttcttct ccgccaattc ccaattctgg aattccgtgg
    10621 cgttcatcaa tagggtaggg tttaatccca tcgggcagac acctacgcat ttggcgcaac
    10681 ggatacaatc ccggatcggc ttgcggacag actcctcttt cgtcagtaat aaaacgccgg
    10741 agcttccttt gcaaaccggc acctcggcgc tgatcaacgc tttacccatc atcggtccgc
    10801 caccgataat cttacccgta ttctcgggca ggccacctgc ggcctcgatc aagcaactga
    10861 tcggggttcc catacgaacc aagaaattgg aaggattagc taccgcctta cctgtgatcg
    10921 tcaccacacg ctcgaacaac ggtttgttct tttgtaccgc ctcgtaaacg gcataagcag
    10981 ttcctacgtt ctgtaccacg gcacccgccg agataggaag cgcaccgctt tttacctgac
    11041 ggcgaataac ggcgtcgatc aattgtttct cgcctccttg cggatattgt accttaagcg
    11101 gcatgatctc tataccttta taatttaccg ccaacttttg cagatgggcg atagcgtccg
    11161 gcttgttatt ctcgataccg atcacggcct tgttcacgtt gaccgctttc attaggatcg
    11221 tgacaccgac taggatttgc tcgcctttct ccagcatcaa cgaatggtcg gaagtaagat
    11281 aaggctcaca ctccacggcg ttgatgatta cgatctctgc cttgtttccg ggaggcggca
    11341 tcaatttcac ctgcgtaggg aaagtcgctc cacccagacc gacgataccg gaagcggcga
    11401 tcttatccac gatttccttg gaagacagcg agcattcctt cactaaggtc tcgctgcggt
    11461 cgatcgtctc ttcccattca tcaccttcca catctatata gatagcggga cgtttgtatc
    11521 cgctagcgtc gagagcgtta tctatcttgt tcactttgcc ggatacggaa gagtggatgt
    11581 tcgctgatac gaaaccaccc gccttggcta gcaatgtacc cacctttacc agatcccctt
    11641 tcttcaccac ggcctgcgcc ggggcgccga tatgctggct gagggggata atcacctgtt
    11701 taggcgtagc gagagccgta attttcttac cggcagacag tttattctcg gggggatgta
    11761 tacctccgat tcgaaatgtc cttagcatac tattagattt taatttagat ttgttttttc
    11821 ttcacttgta gctttcggtg tggcttccgg tttcacggta gcctctgcct tcggcaccgg
    11881 tttcacggtc tccgctttcg gagcgggagc ggcttccttg cgaggaggga aattcagctc
    11941 atgaatagct cctgtcggac atacagccac gcatttgcgg cataaacgac acttcgtata
    12001 atcgatataa gctacgttat ttgttacggt gatcgcctcg aacggacatt ccttggcaca
    12061 tttgccacag ccgatacaag cgttggcaca agccttgcga gcggcggctc ccttgtcctt
    12121 atttacgcaa gaaacgtaaa tccggcgtga tttaggtcct ttctttctta gctcgatgat
    12181 attcttcggg caagccttca cacaagcacc acaggaagta catttttcct cgtctacctc
    12241 ggcgattccc gtagccgggt tgatgtggat agcgtcgaaa gcgcaggcgt tcacgcagtc
    12301 gccataacca aggcaaccga aagaacaatt cgtctcgcct ccgtaaaggg tagaggcgat
    12361 ggcgcaactt ttcgttccat cataagagtt tgtacgtggg cgggcctgac aagttccgtt
    12421 gcaacggaca acggctacca tgggttcggc tgtacccgcc tctttaccca gtatcgtagc
    12481 gaccttggcc atgaccgggc caccaccaac ggggcagagc aatccgtcta atgagtcagc
    12541 ttttacgcaa gcgcctgcga atccggcgca acccggataa ccgcaacctc cacagttcgc
    12601 cccgggaagg acttcctgta cttgcgcgat gcgaggatct tcgtagactt caaatttctt
    12661 ggaagcagcg tagaggaaaa ccgctccgac cgccccgatt gctcctaatg aaataacggc
    12721 aattaaaatc atgatatatt atcaattaag ttttttcaaa gtaaatataa atcgtctttt
    12781 tagtttgtca cgcattaagt atagtataca gtaataaggt agtaaaagcg ataaaccggt
    12841 taacccgctc gtggtctcgt cccattgtag attcgtaccg atcacgatgg cccccacgac
    12901 tatcaccaaa ggaatgacaa atgccagcaa tacggcctga agccccatgg aattttgtcc
    12961 gcatattatc acttcctcgt taacgcaaaa ccgtcccgac cgatcgggta cctcaatgat
    13021 cttatccttt ttctcggatg ccgagcacat agactgtgcg tggcatcccg agcatgcgga
    13081 ttgttgggta atgcggacga agacggtgtc gccatcgatc ttctctacaa atcctgtatg
    13141 atttatactt tcgctcatat ttgtaatctc gacattgcaa aatcaaggca aaagtaagta
    13201 taatttagaa actatgtcac gattaacaaa gtttattatt cgaaatctta aaacctagct
    13261 taccatttgt aattaaaacc gaaacttaac aactcattaa gctggaaata actcttgtta
    13321 tcctctgttt tttccactcc atcgtcgtat ctaaggtgaa aatagatacg tgtggagaaa
    13381 aagcggctga tggccagaac caaggtattc tcgaactccc cgatggtatg atcgccataa
    13441 gtggtaaaga aataaagacg ggattgccag cttacgttac ggttgaaatc aaaggcgagg
    13501 tctgcacgga tcgtggaacc tatttggctt agcttgttat tgaactcacc ggtttcctcg
    13561 tttttcttga aaccgtgacg gctataatcg atctcttgtg tcgtatacat atatgtatag
    13621 gagatcggcg ccaagttggt gctgaattta accttcttat gcttgtcggt aaattgtttc
    13681 tccagctcgt atttcatacc gagaccgaag ttgatagaga acggggcaag gaacgcggcc
    13741 tgtttgatgt gctcgttctc ttgatagttg gtgaagaact gggtcttgaa ctcagcgtcg
    13801 aacgtatagt accatttgtt gaacgcttgg tagccgacgt tgctgtgtat acggaatacg
    13861 tcgtcaccga tcttatagtt ccttaaggta tccttcggtg ccgtatatac gctggctttg
    13921 aattccagtt cgttcgttac ttgtacctta tctttcttat agtcgtattt taaattgttc
    13981 ttggtgaaca ggttcaagtt gctacttcca cccttgtacc agttctccga aacgtagttc
    14041 tgggagaatt ggacggcgct ctcgaaggcc gatatccagt atctccgctc cgggataaag
    14101 cgggcgggag cgtctacgtc ctcaaaattg gcatcagcct ccaccttgat cggcaagtcc
    14161 tcataaatat tcttcttgat gaatttaggt ttgatcacct cattgggcag atccctctcg
    14221 gagtagcgga aataagtcgg gtaattgttc tgcacatatt tgtaagccat ctcctcgaac
    14281 tgtttgtttc gctccagatc tttgaagatg gagtctgtcc ggtataagtt atcataggga
    14341 gtcctctcct tcaatgaatc gaagttatag aatatcaagt ttttgggtag ataatctccc
    14401 cggaaaacga tcggcatgaa taaagggttt acgatcacgg tgtctcggaa ggtcatcgta
    14461 ttatcgaaag ccgtggaggc gtctcgtacc agacgggccc aatacatcgc ctcgtccgag
    14521 atctccagtt cgtctttttt caagaaacgc agtaaattcg tgcttggggc caagggcgcc
    14581 gagtaagtct tgttttgttt ctcgaattgt ttacgaatgt ctacgatgtt gtctaattcc
    14641 tcttcgccaa gattgatcgc aggaatcgta tcatccgata cgacttgctg tgcgggacgt
    14701 tgaactatcg ttccggtaac tagttggttc tcttggctgt atgccgagct cccaattagt
    14761 gaaagtaata atagcgcata cacaccatgc ctcttcatca tcataatacc ttatttacat
    14821 ctattagttg tagtggtcgc aaaattagct aaaaagaatg atatacaaca tacgatctgt
    14881 ctcttataca catctgacgc tgccgac
//
