LOCUS       c00020_gnlPro..        12887 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CONDBLOG_20.
ACCESSION   c00020_gnlPro..
VERSION     c00020_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 18:31:56
            Original ID  :: gnl|Prokka|CONDBLOG_20
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12887
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12887
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2:2887]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3..2887
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..12887
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..12887
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             3..455
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg20_1"
                     /sec_met_domain="TPP_enzyme_C (E-value: 5.2e-41, bitscore:
                     131.2, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="SGGLGTMGFGLPAAIGATFGRPDRTVCVFMGDGGLQMNIQELGTI
                     MEQKAPVKIICLNNNYLGNVRQWQAMFFNRRYSFTPMLNPDYMKIASAYDIPSKRVFSR
                     EELKAAIDEMLSTDGAFLLEACVVEEGNVLPMTPPGGSVNQMLLEC"
     CDS             474..1037
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg20_2"
                     /sec_met_domain="ALS_ss_C (E-value: 1.9e-19, bitscore:
                     60.9, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDKTLYTIIVHSENIAGLLNQVTAVFTRRQINIESLNVSASSIK
                     GVHKYTITAWTDKDTIEKVVKQIEKKIDVIQAHYFTEDEIYFHEIALYKVSTPAFQETP
                     EASKVIRRYNARIVEVNPVFSIVEKNGMSEEITSLYEELRALKCVLQFVRSGRVAITTS
                     CFERVNEFLDGQEAKYKQSKKEQE"
     CDS             1037..1780
                     /locus_tag="ctg20_3"
                     /transl_table=11
                     /translation="MSEENKIGTYQFVAEPFHVDFNGRLTMGVLGNHLLNCAGFHASDR
                     GFGIATLNEDNYTWVLSRLAIELDEMPYQYEKFSVQTWVENVYRLFTDRNFAVIDKDGK
                     KIGYARSVWAMINLNTRKPADLLALHGGSIVDYICDEPCPIEKPSRIKVTSNQPVATLT
                     AKYSDIDINGHVNSIRYIEHILDLFPIELYQTKRIRRFEMAYVAESYFGNELSFFCDEV
                     SENEFHVEVKKNGSEVVCRSKVIFE"
     CDS             1844..2887
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg20_4"
                     /sec_met_domain="IlvN (E-value: 1.1e-46, bitscore: 149.6,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 6.1e-40, bitscore: 128.0,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQLNFGGTVENVVIRDEFPLEKAREVLKNETIAVIGYGVQGPGQ
                     ALNLRDNGFNVIVGQRQGKTYDKAVADGWVPGETLFGIEEACEKGTIIMCLLSDAAVMS
                     VWPTIKPYLTAGKALYFSHGFAITWSDRTGVVPPADIDVIMVAPKGSGTSLRTMFLEGR
                     GLNSSYAIYQDATGNAMDRTIALGIGIGSGYLFETTFIREATSDLTGERGSLMGAIQGL
                     LLAQYEVLRENGHTPSEAFNETVEELTQSLMPLFAKNGMDWMYANCSTTAQRGALDWMG
                     PFHDAIKPVVEKLYHSVKTGNEAQISIDSNSKPDYREKLEEELKALRESEMWQTAVTVR
                     KLRPENN"
     CDS             3080..3259
                     /locus_tag="ctg20_5"
                     /transl_table=11
                     /translation="MKKLFTYRKSIRMKMISSLMNSISECYIKRYLSYSLPNGSCNTIS
                     SPFYISCSISDSLI"
     CDS             complement(3420..5378)
                     /locus_tag="ctg20_6"
                     /transl_table=11
                     /translation="MFNKMKYIFVSGRRFITFASIMNNHPKSPIIDLQQQQLLLRMEYE
                     HEKEEFKRQTETMGVARKVKRGLCWYPASPGRSYYNSLNQLVIDITRTENKEIEHSFEF
                     GRPVCFFRQSFDGKVNYMNFIATVSYADDERMVVVLPSAGALLELQTEEVLGVQLYFDE
                     TSYRAMFEALEDTIRAKGNRLAELRDTLLGTQKPGFRELYPVRFPWLNSTQETAVNKVL
                     CTRDVAIVHGPPGTGKTTTLVEAIYETLHREPQVLVCAQSNTAVDWICEKLVDRGVPVL
                     RIGNPTRVNDKMLSFTYERRFENHSAYPELWGIRKSIREMGSRMRRGSYSEREGMRSRM
                     SRLRDRATELEILINADLFDSARVIASTLVSSNHRLLNGRRFPTLFIDEAAQALEAACW
                     IAIRKADRVILAGDHCQLPPTIKCIEAARGGLDHTLMEKVVQQKPSAVSLLKVQYRMHE
                     AIMRFPSEWFYNGELEAAPEVRNRGILDFDTPMNWIDTSEMDFHEEFVGESFGRINKQE
                     ANLLLQELEAYISRIGKARILDESIDFGLISPYKAQVQYLRSKIRGSSFLRPFRSLITV
                     NTVDGFQGQERDVVFISLVRANEDGQIGFLNDLRRMNVAITRARMKLVILGDATTLTKH
                     AFYRKLIQYIRQEAVSS"
     CDS             5433..6839
                     /locus_tag="ctg20_7"
                     /transl_table=11
                     /translation="MVYDLTMLEAFYSAYKGKVEHVRAVLKRPLTLAEKILYAHLFNEG
                     DLKNYKRGEDYVNFRPDRVAMQDATAQMALLQFMNAGKEKVAVPSTVHCDHLIQAYKGA
                     KEDIATATKTNEEVYDFLRDVSSRYGIGFWKPGAGIIHQVVLENYAFPGGMMVGTDSHT
                     PNAGGLGMVAIGVGGADAVDVMTGMEWELKMPRIIGVRLTGKLSGWTSPKDVILKLAGI
                     LTVKGGTNSIIEYFGPGTASLSATGKATICNMGAEVGATTSLFPFDGRMATYLRATGRD
                     RIVELAEAVDCELRADQQVTDEPEKYYDRVIDIDLSTLEPYINGPFTPDAATPISEFAE
                     KVLLNGYPRKMEVGLIGSCTNSSYQDLSRAASLARQVKEKNLSVASPLIINPGSEQIRA
                     TAERDGMMDDFMQIGAVIMANACGHASVSGNVIRTTRRGRTRSSHPSTVTLPNVRTAIR
                     THTPLLLLPN"
     CDS             complement(6701..7366)
                     /locus_tag="ctg20_8"
                     /transl_table=11
                     /translation="VLATGAFSVIFFSHDNGGDSFGFIHFGCARNGSVGVCRTVPHVVR
                     FAIESIHGSHQHIIRNILQMSAKTQPRSRHRNMVGSTFALRLNQQGHIEYILSVPSGER
                     SQQLQALGSRVDVDRCFRPAGGDIAFITGGKSSQGEFFAFRFGQFHFLAVMVHQSVFQR
                     IEAKITGNGQCHRQFGRSNKGVCVRIAVRTFGKVTVEGCDDRVLPRRVVRMTLPLTDA"
     CDS             7373..7675
                     /locus_tag="ctg20_9"
                     /transl_table=11
                     /translation="MEPRFLNVRVILAKSFARIHETNLKKQGMLALTFADKADYDKIQE
                     HDLLSVIGLPDFAPGRNLTVVLHHEDGTKESFEAQHTYNEQQIAWFRAGSALNAR"
     CDS             7690..8880
                     /locus_tag="ctg20_10"
                     /transl_table=11
                     /translation="MNKITMQKDGTLSVPDVPVVPYITGDGVGAEVTPSMQAVVNAAVQ
                     KAYGGKRRIEWKEVLAGERAFNETGSWLPDETMKAFQEYLIGIKGPLTTPVGGGIRSLN
                     VALRQTLDLYVCLRPVRWYQGVHSPVKAPEKVNMCVFRENTEDIYAGIEWEAGTPEAEK
                     FYQFLKNEMGVTKVRFPETSSFGVKPVSREGTERLVRAACQYALDHHLPSVTLVHKGNI
                     MKFTEGGFKKWGYELAQREFGDALADGRLVIKDCIADAFLQNTLLIPEEYSVIATLNLN
                     GDYVSDQLAAMVGGIGIAPGANINYKTGHAIFEATHGTAPNIAGKDVVNPCSIILSAVM
                     MLEYLGWKEAAALIEKALEQSFLDARATHDLARFMPGGTSLSTTAFTREIVERIEK"
     CDS             8906..10249
                     /locus_tag="ctg20_11"
                     /transl_table=11
                     /translation="MKKEYLIYKLSEEMKEATRIDNELFPKFDVKRGLRNEDGTGVLVG
                     LTKIGNVVGYERIPGGGLKPIPGKLFYRGYDVEDISHAIIKEKRFGFEEVAYLLLSGRL
                     PDKEELASFCELINDNMALEQKTKMNIIELEGNNIMNILSRSVLEMYRFDPDADDTSRD
                     NLMRQSIDLISKFPTIIAYAYNMLRHATFGRSLHIRHPQEKLSIAENFLYMLKKDYTEL
                     DARTLALLLILQAEHGGGNNSTFTVRVTSSTGTDTYSAIAAGIGSLKGPLHGGANIQVA
                     DMFHHLQENIKDWKSVDEIDTYFTRMLNKEVYNKTGLIYGIGHAVYTISDPRALLLKEL
                     ARDLAREKGKEEEFAFLELLEERAIATFGRVKNNGKTVSSNIDFYSGFVYEMIGLPQEI
                     FTPLFAMARIVGWCAHRNEELNFEGKRIIRPAYKNVLDDLAYIPIKKR"
     CDS             10747..11508
                     /locus_tag="ctg20_12"
                     /transl_table=11
                     /translation="MSITAFNLFLGVMSLIALIVFIALYFVKAGYGIFRTASWGVAISN
                     KLAWILMEAPVFLVMCWMWMHSERRFDPVILTFFIFFQIHYFQRAFVFPLLLTGKSKMP
                     LAIMSMGILFNLLNGYMQGEWIFYLSPEGMYHSGWFTSAWFIAGSLLFFAGMLMNWHSD
                     YIIRHLRKPGDTRHYLPQKGMYRYVTSANYLGEIIEWAGWAILTCSLSGLVFFWWTVAN
                     LVPRANAIWHRYREEFGSEVGGRKRVFPFIY"
     CDS             11547..12770
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Oxidored_FMN"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg20_13"
                     /sec_met_domain="Oxidored_FMN (E-value: 6.4e-53, bitscore:
                     171.3, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MESKLFTPVTFGPLTLRNRTIRSAAFESMCPGNAPSQMLLDYHRS
                     VAAGGVGMTTVAYAAVTQSGLSFDRQLWLRPEIISGLREVTGAIHTEGAAAGIQIGHCG
                     NMSHKKICGTTPISASTGFNLYSPTFVRGMKKEELPEMARAYGRAVHLAREAGFDAVEV
                     HAGHGYLISQFLSPYTNHRKDEYGGSLENRMRFMEVVMNEVMTAAGSDMAVFVKMNMRD
                     GFKGGMETDETLQVAKRLLALGAHALVLSGGFVSKAPMYVMRGAMPIRSMAYYMDCWWL
                     KYGVRMFGKWMIPTVPFREAYFLEDALKFRAALPEAPLIYVGGLVSREKIDEVLDAGFD
                     AVQMARALLNEPEFVNRMRREEQARCICGHSHYCIGRMYTIEMACHQHLKEKLPPCLQR
                     EIEKLEKQ"
ORIGIN
        1 cttcgggtgg acttggcacg atgggttttg gccttccggc agctatcgga gctactttcg
       61 gccgtcccga ccgcactgta tgtgtattta tgggtgacgg cggactgcaa atgaacattc
      121 aggaactggg tacgatcatg gaacagaaag ctccggtgaa gattatctgc ctgaacaaca
      181 attatctcgg caacgtgcgc caatggcagg ctatgttctt taatcgccgt tattcattta
      241 ctccgatgct gaatccggat tacatgaaaa tcgcttccgc ctacgatatt ccttccaaac
      301 gtgtcttttc acgggaagaa ttgaaagcgg ccatcgacga aatgctctcg acagacgggg
      361 cgttcctgct cgaagcctgt gtggtagaag aaggcaatgt cctcccgatg acccctccgg
      421 gcggttcagt caatcagatg ttgctggaat gttaatcctt aatttagaaa gttatgagtg
      481 ataagacatt atatacgatt atagttcatt ctgaaaatat agccggattg ctgaatcagg
      541 tgaccgctgt atttacccgt cggcaaataa acatcgagag tttgaacgtt tctgcttctt
      601 ccattaaagg agtacataaa tatacgatta cagcgtggac tgataaggac actatcgaaa
      661 aggtggtgaa gcagatcgaa aagaagattg atgtgattca ggcgcactat tttacggaag
      721 acgagattta tttccatgag atagccttat ataaggtatc tactcctgct tttcaggaga
      781 ctccggaagc atctaaagtg atccgcagat ataatgcccg cattgtagag gtgaatccgg
      841 tattctctat cgtcgagaag aacggcatga gtgaagagat tacttccctt tacgaagaac
      901 ttcgggcttt gaaatgtgtg ctgcaatttg tccgttcggg ccgtgtggct attactacca
      961 gctgtttcga acgtgtgaat gagttcctgg acggacagga agcgaagtat aagcaaagta
     1021 aaaaggaaca ggagtaatga gtgaagaaaa taaaataggg acttatcagt ttgtggcaga
     1081 gccgtttcac gtagatttta acggccgcct gaccatgggc gtgctgggga atcatctgct
     1141 gaattgcgca ggttttcatg ccagcgaccg tggatttggt attgctacgc tgaacgagga
     1201 caattacaca tgggtgcttt cccgtctggc gatcgagctg gacgagatgc cttaccaata
     1261 cgagaagttc tcggttcaga catgggtgga gaatgtctat cgtctcttta ccgaccgtaa
     1321 ctttgccgtc attgacaagg atggaaagaa gatcggctat gcccgttccg tatgggcgat
     1381 gatcaatctg aatactcgta agcctgccga tctgttggca ttgcatggag gaagcatcgt
     1441 cgattatata tgcgatgaac cctgcccgat agaaaagcct tcgcgtatca aggtgacaag
     1501 caatcagcct gttgcgacgc tgacggcaaa atacagtgat atcgatatta acggacacgt
     1561 aaacagtatt cgttatatcg agcacatact tgacttgttt ccgatagaac tgtatcagac
     1621 gaaacgtatc cgccggtttg aaatggcgta tgtggctgaa agttatttcg gaaatgaact
     1681 ctctttcttc tgtgatgagg tgagtgaaaa cgagtttcat gtagaggtga agaaaaacgg
     1741 cagcgaggta gtatgccgtt ccaaagtgat atttgaataa tatagagtat aaaatcaatt
     1801 aataacagat ggcgcaagtc atcaaaacaa aaaaacaaaa aaaatggcac agttgaattt
     1861 tggcggaact gtagaaaatg tagttatccg tgatgaattt ccattggaaa aagctcgtga
     1921 agtattgaaa aatgaaacaa tcgctgtaat cggttatggc gtacaaggtc ccggacaggc
     1981 tctgaacctt cgtgataacg gtttcaatgt aatcgttggt caacgccagg gaaagacata
     2041 tgacaaagcg gttgctgacg gatgggttcc gggtgaaact ttgttcggta ttgaagaagc
     2101 ttgcgaaaaa ggtacgatca ttatgtgcct gttgtctgat gcagcagtaa tgtctgtatg
     2161 gcctactatc aagccttacc tgactgcagg aaaagctctt tatttctctc atggttttgc
     2221 tattacatgg agtgaccgca caggtgtagt tcctcctgca gatatcgacg taatcatggt
     2281 tgctcctaaa ggttcgggta catccttgcg tactatgttc cttgaaggtc gcgggttgaa
     2341 ctcttcatac gctatctatc aggatgcaac aggcaacgct atggacagaa caatcgcatt
     2401 gggtatcggt atcggttcag gttatttgtt cgaaacaact ttcatccgcg aagctacttc
     2461 cgacctgaca ggcgaacgtg gttcattgat gggagctatc cagggtctgt tgctggcaca
     2521 atacgaagtg ttacgtgaaa acggtcacac tccttccgaa gcattcaacg aaactgtaga
     2581 agagctgact cagtcattga tgccgttgtt tgcaaagaac ggtatggact ggatgtatgc
     2641 taactgctct actacagctc aacgtggtgc tctcgactgg atgggcccct tccacgatgc
     2701 tatcaaaccg gtcgttgaaa agttgtatca cagtgtgaag actggtaacg aagcacagat
     2761 ttcaatcgac tctaactcca aaccggatta tcgtgagaaa ctggaagaag aactgaaagc
     2821 attgcgcgaa agcgaaatgt ggcagactgc cgtgacagtt cgtaaacttc gtccggaaaa
     2881 taattaatca gacttatact atataagttt ttcaaaaggc gggaaaatca tcttttcccg
     2941 cctcttttat gtgtatgcca ctcttttgaa tgacagaata aggatgaaag tagcaaaaaa
     3001 gattaaaaga tactgataat ataggtgaaa aagagcattt atgattacct ttacggcaac
     3061 aaataaaaca gaataggcaa tgaagaaact ttttacttac agaaaatcga tacgtatgaa
     3121 gatgatttct tctttaatga atagtatatc agaatgttac attaaaagat atttaagtta
     3181 ttctctaccg aatggtagct gtaataccat ttcaagtcct ttttatattt cgtgttccat
     3241 tagtgattcg ttgatatgat gcagaatttt attctgtagc aggaaaaagt atgcgttaaa
     3301 ttgaatttaa gacagagctt ttggaacaga atttagtggg aaaataacat tgtttgtttt
     3361 gtttgtaaat gggagtcttc tttcgtgaga aagggggctt ctttttttat cccgatgatt
     3421 caggaggata ccgcttcctg ccggatatac tgtatcagtt tccggtagaa cgcatgcttg
     3481 gtaagagtgg ttgcatctcc caaaatcaca agtttcatcc gggcgcgggt aatggctacg
     3541 ttcattcgtc ttaaatcatt cagaaaaccg atctgtccgt cctcgttcgc ccggacgagg
     3601 ctgataaaga cgacatcccg ttcctgtccc tgaaagccgt ctaccgtgtt gaccgtgatg
     3661 aggctgcgga aagggcggag aaaactgctt cctctgattt tacttctcag gtattgcact
     3721 tgcgccttgt agggcgaaat cagaccaaag tcgatgctct cgtccaggat gcgtgctttg
     3781 ccgatccggc tgatataggc ttccagttct tgcagtaaca agttggcttc ctgcttgttg
     3841 atgcgcccga agctctcgcc tacaaactct tcgtggaagt ccatttccga ggtatctatc
     3901 cagttcatgg gagtgtcgaa gtcaaggata ccccggttgc gcacttccgg tgcggcttcc
     3961 agttctccgt tgtagaacca ttcggaggga aagcgcatga ttgcctcgtg catccggtat
     4021 tgcactttga gcagcgagac ggcagaaggt ttttgctgca cgactttttc cattaaagta
     4081 tggtccagtc cgccacgggc ggcttcgata catttgattg taggagggag ctggcaatgg
     4141 tcgccggcaa gaatcacacg gtcggccttt cggatggcga tccaacaggc ggcttcgagt
     4201 gcctgggcgg cttcatcgat aaataaggtg gggaaacgcc gtccgttgag caaacggtga
     4261 ttgctgctga ccagcgtgga agcaatcaca cgggcactgt cgaaaagatc ggcgttgatc
     4321 aggatttcca gttcggtggc acggtcgcgg aggcggctca tccggctgcg cattccttcc
     4381 ctttcggagt aacttccccg acgcatccgg ctgcccattt cacggatcga ttttcggatt
     4441 ccccaaagtt cggggtaggc cgaatgattc tcaaagcggc gttcgtaagt gaaagaaagc
     4501 attttgtcat taacacgtgt agggttacca atgcggagga caggcacacc ccggtctacc
     4561 agtttctcgc aaatccagtc cacagccgta ttactttggg cgcagaccag cacctgcggt
     4621 tcgcggtgaa gcgtttcgta aatggcttcc acgagcgtgg tagtctttcc ggttcccgga
     4681 gggccgtgaa cgatggcgac atcgcgtgtg cataacactt tgtttacggc tgtttcctgc
     4741 gtgctgttca gccacgggaa acggacggga tataattcgc ggaatcccgg cttttgtgtt
     4801 cccagcaagg tgtcccggag ttcggcaagg cggttgccct tagcgcggat tgtgtcttcc
     4861 agcgcttcga acatggcacg ataggacgtt tcatcgaaat aaagttgtac acccagcacc
     4921 tcttccgttt gcagttccag caaggcgccc gcactgggaa gcacgaccac catccgttcg
     4981 tcgtccgcat aactcaccgt tgcaatgaaa ttcatgtaat tcacttttcc gtcaaatgac
     5041 tgccggaaaa agcagacggg acgaccgaat tcgaaggaat gctcgatttc tttattttcg
     5101 gtgcgtgtaa tatctattac aagttgattt agagaattat agtaacttcg accgggagag
     5161 gcgggatacc agcacagacc acgtttcact ttgcgggcga cacccattgt ttcagtctgc
     5221 cgcttgaatt cctccttttc gtgttcatac tccatgcgta gcaggagttg ctgttgctga
     5281 aggtcgatga ttggactttt cggatgatta ttcataatag acgcaaaggt aataaatctt
     5341 cttcctgaga cgaaaatata tttcattttg ttaaacattc ctcgaacgcc gttcgttatt
     5401 tttatagata gactaaaaaa aataaaagca atatggtgta tgatttgact atgttagagg
     5461 ctttttattc tgcttataaa ggaaaagtgg aacacgtgcg ggctgttttg aaacgcccat
     5521 tgacgttagc cgagaagatt ctgtatgccc acctgttcaa tgagggcgat ctgaaaaact
     5581 acaagcgggg tgaagactac gtaaatttcc gtcccgaccg cgtcgctatg caggacgcga
     5641 ctgcccagat ggcattgctt caattcatga atgcaggaaa agaaaaagtg gctgttccct
     5701 ccaccgtgca ctgtgaccac ttgatacagg cgtacaaagg agcaaaggag gacattgcta
     5761 cggcaaccaa aacaaacgaa gaagtttacg actttttgcg cgatgtatcc tctcgctacg
     5821 gcatcggctt ttggaagccg ggtgccggta tcattcacca ggtagtgctc gaaaattacg
     5881 ctttccccgg cggaatgatg gtaggaaccg actctcacac tccgaatgcc ggaggactgg
     5941 gcatggtggc catcggcgtc ggcggtgcgg atgccgtaga cgtgatgaca ggtatggaat
     6001 gggaactgaa aatgccaagg attatcggtg tccgcctgac cggaaaactg agcggctgga
     6061 cttccccgaa agatgtcatc ctgaaacttg cagggattct gaccgtaaaa ggaggcacga
     6121 actccatcat cgaatatttc ggaccgggaa cagcttccct gtcggctacc ggcaaagcga
     6181 ccatttgcaa tatgggtgcg gaagtaggag ctaccacttc gcttttcccg ttcgacgggc
     6241 gcatggctac ttatctgaga gccaccggca gggatcgcat cgtggaactg gcggaagccg
     6301 tggactgtga gctccgtgcg gaccaacagg tgacggacga accggaaaag tactacgacc
     6361 gtgtcatcga catcgatttg tctacgctcg aaccttatat caacggccct ttcacaccgg
     6421 atgccgctac ccctatttct gaatttgcag aaaaagtatt actgaacggc tatccgcgta
     6481 agatggaagt cggactgatc ggttcgtgta ccaactcttc ttaccaagat ctcagccgtg
     6541 ccgcatccct tgcaaggcag gtgaaggaaa agaatctgag tgtggcttcc ccgttgatca
     6601 tcaatccggg ttccgagcaa atccgcgcta ctgccgaaag agacggaatg atggatgact
     6661 tcatgcagat cggcgccgtg atcatggcaa atgcctgcgg tcatgcatcg gtcagtggca
     6721 acgtcatacg gacgacccga cgcggaagaa ctcgatcgtc acatccttca accgtaactt
     6781 tgccaaacgt gcggacggca atccgaacac atacgccttt gttgcttctc ccgaactgac
     6841 gatggcactg accattgccg gtgatctttg cttcaatccg ctgaaagaca gactgatgaa
     6901 ccatgacggc gagaaagtga aactggccga accggaaggc gaagaactcc ccttgagagg
     6961 atttacctcc ggtaatgaag gctatatcgc ccccggcggg acgaaaacag cgatcaacgt
     7021 caacccggct tcccaacgcc tgcaactgct gactcctttc cccgcttggg acggacaaga
     7081 tatactcaat atgcccctgc tgattaaggc gcagggcaaa tgtactaccg accatatttc
     7141 gatggcggga ccgtggctgc gttttcgcgg acatttggag aatatttcgg ataatatgct
     7201 gatgggagcc gtgaatgctt tcaatggcga aacgaacaac gtgtggaacc gttcgacaaa
     7261 cacctacgga accgtttcgg gcacagccaa aatgtataaa tccgaaggaa tcccctccat
     7321 tgtcgtggct gaagaaaatt acggagaagg ctccagtcgc gagcacgcgg caatggaacc
     7381 ccgtttcctg aatgtgcgtg tgattctcgc caagagcttc gcccgtatcc acgaaacgaa
     7441 tctgaaaaag cagggcatgc ttgcccttac ctttgcggat aaagcggatt atgacaagat
     7501 acaggagcac gacctccttt cagtcatcgg cttgcccgac tttgctccgg gacggaatct
     7561 gaccgtcgtt cttcatcacg aagacggaac gaaagagagt tttgaagcgc aacatacata
     7621 caacgaacag cagattgcct ggttccgtgc cggctctgcc ttgaatgcca gataattaaa
     7681 atgatagaaa tgaacaaaat aaccatgcaa aaagatggta cgctgtcggt gcccgatgtg
     7741 cctgtcgtac cttatattac cggagacgga gtaggagcgg aagtgactcc gtcaatgcaa
     7801 gccgttgtga acgcggctgt tcagaaagca tacggcggca aacgtcggat tgaatggaaa
     7861 gaagtgctgg cgggcgaacg cgctttcaac gagacaggct cttggctgcc ggatgaaacg
     7921 atgaaggctt tccaagaata tctgatcggc atcaagggtc cgctgacgac ccctgtcggc
     7981 ggtggaatcc gttctttgaa cgtagctttg cgccaaacct tggatttata tgtttgtttg
     8041 cgtccggttc gttggtatca aggcgttcat tctccggtga aagcaccgga aaaagtgaac
     8101 atgtgtgtgt tccgtgaaaa tacggaggat atatatgcag gaatcgagtg ggaggcaggt
     8161 actcccgaag ccgaaaagtt ctatcaattc ctgaaaaacg agatgggagt gacgaaagtc
     8221 cgcttccccg agacctcttc ttttggggtg aaacctgttt cccgtgaggg cacggaacgt
     8281 cttgtgcggg ctgcctgcca gtatgcgctc gaccatcatc tgccttctgt gacactggtg
     8341 cacaaaggaa acattatgaa gttcaccgaa ggaggtttca agaaatgggg ctatgagctg
     8401 gcgcaacgtg agtttggcga cgcgctggca gacggccggc tggtgataaa ggactgcatt
     8461 gccgatgctt ttctgcaaaa tacattactg attcccgaag agtattccgt gattgccacg
     8521 ctgaacctga acggagacta tgtttccgac cagttggcgg caatggtagg cggcatcggc
     8581 attgctccgg gagcaaatat taactacaag acggggcacg ccatttttga agcgactcat
     8641 ggaaccgccc ccaacattgc cggaaaggat gtcgtgaatc cttgttctat cattctttcg
     8701 gcggtgatga tgcttgaata tctgggatgg aaagaagcgg ccgcgcttat cgaaaaggcg
     8761 ctggaacaga gtttcctcga tgcccgtgcc acgcacgatc tggctcgctt tatgccggga
     8821 ggtacatccc tgtctaccac cgctttcaca cgcgaaattg tggaaagaat cgaaaagtaa
     8881 atgtaacgat taaaaacgaa gtattatgaa gaaagagtat ttgatttaca agctctccga
     8941 ggagatgaaa gaggcaaccc ggattgacaa tgaattgttc cccaagtttg acgtgaagcg
     9001 tggactacgt aatgaagacg gcaccggtgt attggtaggt ctgacaaaga ttggtaatgt
     9061 ggtgggttac gaacgtatcc ccggcggcgg tctgaagcct attccgggaa aattgttcta
     9121 tcgaggctat gatgtggaag acatttccca cgccatcatc aaggaaaaac gtttcggctt
     9181 cgaagaagtg gcttatctgc tactctccgg tcgtctgccg gacaaggaag aactggcttc
     9241 gttctgcgaa ctgatcaatg acaatatggc gctcgagcag aagacgaaaa tgaatattat
     9301 cgagctggag ggaaataata tcatgaatat cctttcgcgc agcgtactcg aaatgtatcg
     9361 tttcgatccc gatgccgacg atacttcccg cgacaatctg atgcgccaga gtatcgatct
     9421 tatctccaag ttcccgacca tcattgcgta tgcttataat atgctccgcc atgctacatt
     9481 cggccgttcc ctgcatatcc gtcatccgca ggaaaaactc tctattgccg agaatttcct
     9541 ctatatgctc aaaaaagatt atacggaact ggatgcccgt acgctcgcct tgctattgat
     9601 tttgcaggca gaacatggcg gtggtaacaa ctcgactttc acggttcgtg tgacttcttc
     9661 caccggaaca gatacatact cggccatcgc cgcaggtatc ggttcgttga aaggcccgct
     9721 tcacggaggc gcgaatatcc aggtggccga tatgttccat cacttgcagg agaacatcaa
     9781 ggactggaag agcgtggacg agatagatac ctatttcaca cggatgctga ataaggaagt
     9841 gtataataag accggattga tttacggtat cggtcatgct gtttatacga tttccgatcc
     9901 tcgtgcgctg ttgctgaaag aactggctcg cgaccttgcc cgtgagaaag gaaaagaaga
     9961 ggagttcgct ttcctcgaac tgcttgaaga gcgtgccatc gctactttcg gacgtgtgaa
    10021 gaacaacgga aagacggttt ccagcaatat cgacttctat tcgggcttcg tatatgagat
    10081 gattggtttg ccgcaggaga ttttcactcc gctgtttgcc atggctcgta ttgtcggctg
    10141 gtgtgcgcac cgcaatgaag aactgaactt cgagggcaaa cgcattatcc gtccggctta
    10201 taaaaatgtt cttgatgatc tggcttatat ccccatcaag aaacgctgat aagaacaaat
    10261 ccttttatgc aataataact aacctcagac gtacatctcg gcaatccctg catgtacgtc
    10321 tcggtaatcc ccagttgtac atcttggtag tacccggttg tacgtctggg gtgacttgtt
    10381 tcaggaagaa cgtccgatgt tcatttaaca tttaacactt tgcggctgct gtatttttca
    10441 tccgatggag gctaaggcat ttatcgttgg tagaaagggc acagcctggc aggtagaaac
    10501 gcccttttaa cgctacgtta aaagggcgtt tctacaatcg atgaattata tattctattc
    10561 ctttggatat cagtgaacta tgtgctaaaa gcccatggtg tcatatgaaa gagaacacgg
    10621 gatggaaaaa agataattgt gatattcata agtttcctgt ccggtcaata cgaatagttc
    10681 tttcggtttt ttgtggccat tcttttcttt ttttgttatt tttgtgaatc tcaaaagaaa
    10741 atcaagatga gtataactgc ctttaatcta tttttgggcg tcatgagtct gatcgctctg
    10801 attgttttca tcgccctcta ctttgtgaaa gccggttatg ggatatttcg cactgcctcc
    10861 tggggagtcg ccatttccaa caagctggcg tggatactga tggaagcccc cgtatttctg
    10921 gtcatgtgct ggatgtggat gcactcggaa cgtcgttttg atccggtcat actgacattc
    10981 tttatcttct ttcagattca ttattttcag cgcgccttcg tctttcccct gctactgacc
    11041 ggaaagagca aaatgccgct ggcaattatg tcgatgggaa tcctgttcaa tctattgaac
    11101 ggctatatgc agggcgaatg gatattttat ctctcacccg agggaatgta tcattccggc
    11161 tggttcactt ccgcatggtt tattgcgggc agtctgcttt tctttgcagg tatgttgatg
    11221 aactggcatt cggactatat catccgtcat ttgcgcaaac cgggggatac ccgtcattat
    11281 ctgccccaaa aagggatgta ccgctatgtc acttccgcca attatctggg cgaaatcatc
    11341 gaatgggcag gctgggcaat actgacctgt tcactgtccg gacttgtatt cttctggtgg
    11401 acagtggcca atctcgtccc ccgtgccaat gcaatctggc atcgctaccg tgaagaattt
    11461 ggctcggaag taggcggacg caaacgtgta tttcctttta tctattgatt tgaaataaat
    11521 tatctattga cataaaatag cgtactatgg aatctaaact tttcacccct gtcactttcg
    11581 gtccattgac gctgcggaat cgtacgatcc gctctgccgc ttttgaaagc atgtgtcccg
    11641 gtaacgcccc ttcacaaatg ctgctcgatt accaccgctc ggtggctgcg ggcggagtcg
    11701 ggatgacgac tgtagcctat gcagccgtga cgcaaagcgg actttctttc gaccgtcagt
    11761 tgtggctgcg tccggaaatc atttccggtt tacgtgaagt gaccggagct atacacacgg
    11821 aaggtgcggc agcaggcatc cagatagggc actgcggaaa tatgtcccat aaaaagattt
    11881 gcggaaccac tcccatttcg gcctctaccg gtttcaatct ctattctcct acattcgtgc
    11941 gtggcatgaa gaaagaagag ttgccggaga tggccagagc ctacggacgg gctgtccact
    12001 tggcacggga agccggcttc gacgccgtgg aggtgcatgc cggacacgga tatctgatca
    12061 gccagttcct gtctccctac accaatcacc ggaaagacga atacggcggc tcgctcgaaa
    12121 atcggatgcg ctttatggaa gtggtgatga acgaggtgat gacagcagcg ggaagcgata
    12181 tggcggtctt tgtaaaaatg aatatgcgcg atggcttcaa aggcggcatg gaaaccgatg
    12241 aaaccttgca agtggccaaa cgcctgctgg cattgggcgc gcacgcattg gtactgagcg
    12301 gaggcttcgt cagcaaagcc ccgatgtacg tcatgcgggg agcgatgccg attcgttcga
    12361 tggcttacta catggactgc tggtggctga aatacggggt tcggatgttt ggaaagtgga
    12421 tgattccgac cgttcctttc cgggaagcct atttcctgga ggatgcactg aaatttcggg
    12481 cggcacttcc ggaagctccg ttgatttatg tgggcggact ggtgtcccgt gaaaagatag
    12541 atgaagtatt ggatgccggc ttcgatgccg tccagatggc acgtgcgttg ctcaacgaac
    12601 cggagtttgt caaccggatg aggcgggaag agcaggcacg ctgtatctgc gggcacagtc
    12661 actactgcat cgggcgcatg tacactattg aaatggcctg ccaccaacat ttgaaagaaa
    12721 aactgcctcc ctgcctgcaa cgggagattg aaaaactgga aaagcaatga gtgaagagaa
    12781 atgggcaatc atcaccggtg ccgacggcgg catgggaacg gaaataaccc gtgccgtagc
    12841 cgaagccggt taccatatta ttatggcttg ctatcgtccg tccaaag
//
