LOCUS       c00070_gnlPro..        13769 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CONDBLOG_70.
ACCESSION   c00070_gnlPro..
VERSION     c00070_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 18:31:56
            Original ID  :: gnl|Prokka|CONDBLOG_70
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13769
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13769
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1569:5793](-)"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      complement(1570..5793)
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
     cand_cluster    1..13769
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /kind="single"
                     /product="Others_HGD_unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13769
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Others_HGD_unassigned"
                     /region_number="1"
                     /rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1,
                     HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and
                     minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2,
                     AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF,
                     ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C,
                     Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and not (minimum(2,
                     [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /tool="gutsmash"
     CDS             3..413
                     /locus_tag="ctg70_1"
                     /transl_table=11
                     /translation="ELSKLRNELYKTTVLLKEHAFNSEKEKEQLSNSLADISHQLKTPL
                     TSIRIMLDNILENPEMDKEVREDFLRDISSQIEWISSLVISLLKIAKFDAGTIKMENEE
                     INVKKLIENVASNLSILLEVKEVHLYPASIMC"
     CDS             461..952
                     /locus_tag="ctg70_2"
                     /transl_table=11
                     /translation="MLLILGQFWVIRKNKTRQDTIEILLQLPFSFIFSAFIDFNMALTS
                     NLHPDNYGMSIALLLTGCMIQSIGVVLELKPKVAMMSAEAFVKYASRRYNKEFGKFKVC
                     FDVTLVTLAVILSLLLSQCIEGVREGSLIAACITGYIVSFLNQKIMTRKTLYKLLPVLK
                     "
     CDS             complement(960..1583)
                     /locus_tag="ctg70_3"
                     /transl_table=11
                     /translation="MTTTNNNEDLEKKIIEAAKELFIENGFAETSMSDIAAKVGINRPA
                     LHYYFRTKDKMFQAVFGNIILSFIPKIHDIIIQQDKPVSESIGEIVDAYYKVFTENPCL
                     PLFMVREMHRDMNHLSTTIKELRLEQYLHKIMDVLQEEMNDGRLKTVPLPFVFYTFYSA
                     LTVPFLTKNLSASFFLEKDDSFEDILVQWKPYIVRQMETLLVAS"
     CDS             complement(1570..5793)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: BcrAD_BadFG"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg70_4"
                     /sec_met_domain="HGD-D (E-value: 3.5e-29, bitscore: 92.0,
                     seeds: 370, tool: rule-based-clusters)"
                     /sec_met_domain="BcrAD_BadFG (E-value: 1.3e-35, bitscore:
                     112.6, seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKIGIDVGSTTAKLVAVDENDNLLFSKYERHNAKAKETILSFLK
                     ELLSEIGDKDISVRITGSIGMGISEKCSLPFVQEVVAAAKAIQKDYSHVTSMIDIGGED
                     AKVVFFNDAEATDLRMNGNCAGGTGAFIDQMAIILGVNIDELNQLAMNATQVYPIASRC
                     GVFCKTDIQNLIAKNVSRENIAASIFRAVAVQTVVTLAHGCDITTPVLFCGGPLTFIPA
                     LRKAFIDYLSLDEKEIILPANGTLLPALGAALFHLDKEDYCKLSHLIDKIDTTLNGNGN
                     LASTGLEPVFASNEEYEAWKERISRHKMISSGLKAGTQDVFIGIDSGSTTTKIVVLDED
                     SRLLYSYYNINGGNPIKAVEEGLNQLNDECLKQNAVLNIKGSCSTGYGEDLIRSAFQLH
                     SGIIETIAHYMAAHYLNKDVSFILDIGGQDMKVIFVNNGVIDRMEINEACSSGCGSFLE
                     TFAKSLGYSAQEFSLAACHSEAPCDLGTRCTVFMNSKVKQVLREGATINDIAAGLAYSV
                     VKNCLYKVLKLKDISVLGKDIVVQGGTMRNDAVVRAIELLSGAEVARCDTPELMGAFGC
                     ALYAMKHQGESVSLDEIINKAQYSARSLYCKSCDNRCLVIRYEFESGKSYYSGNRCEKV
                     FTNGESSNRKGLNVYRQKEELLFHRSAEIAAPEQIIGIPRCLNMYEEYPFWHTLFTSCG
                     IQVCLSDPSNFRKYEHNARMVMSDNICFPAKLVHSHVQDLIEKKVDRIFMPFVIFERKG
                     MEQNSYNCPIVTGYSEVIKSVQSEGIPVDSPAITFKDRNLLFKQCREYLSGLSVDDRTI
                     QQAFQKAESEQHSFINTLVDYNKNILQQTGKGETLTVMLAGRPYHTDSLIQHKVSDMLA
                     DMGVNVIADDLVRQMDIPTDDAHFVAQWAYTNRILKAAKWCATQGKNIQFVEMTSFGCG
                     PDAFLVDEVRDLLMRHNKSLTLLKLDDINNIGSMKLRVRSMIESLKLANADGTEDGVKD
                     FTTVPVYDKSYRDRKILVPYFTPFISPLIPAIMKVAGYDAENLPLSDNDSSEWGLKYAN
                     NEVCYPATLIVGDIIKALKSGKYDISKIAVAITQTGGQCRASNYISLIKKALVDAGYTD
                     IPVISISVGSDIDNDQPAFKVNWMKVVPITFHAVLYSDCIAKFYYASVVREKEAGASAK
                     LRDKYLQLAPEVILRRDIKGLNSLLQSAITEFNEVCRAVDTPKVGIVGEIFLKFNPFAQ
                     KEIIDWLIGRKIEVVPPILADFFMQGFVNRKVNTDSYIKNRQLPEFIYDWIYKFVKKQI
                     DKINETASKFRYFAPFNDIFEEAEGAKSVISLNAQFGEGWLLPAEIVSYARQGVNNVVS
                     LQPFGCIANHIVSRGVEKRIKSFYPDINLLSLDFDSGVSDVNITNRMLLFIDNLKNATM
                     NYDNN"
     CDS             complement(5911..9219)
                     /locus_tag="ctg70_5"
                     /transl_table=11
                     /translation="MKKIIISLALVLTALSSYAITPLWMRDARISPDGKEIVFCYKGDI
                     YKVPVQGGTATQLTTQASYEANPVWSPDGKQIAFASDRNGNFDLFIMSADGGTARRLTY
                     HSASEIPSAFTPDGKFVLFSASIQDPAQSALFPTGAMTELYKVPVTGGRTEQVLATPAE
                     WVCFDKSGKNFLYQDRKGFEDEWRKHHTSSITRDVWLYDASTGKHTNLTNREGEDRNPV
                     YAPDGNSVYFLSERNGGSFNVYNFALNTPQEVKAITTFRTHPVRFLSISDKGTLCYTYD
                     GELYTQEPNARPKKVNVDLVHDDEKEIATLRFSQGATSASVSPDGKQVAFIVRGDVFVT
                     STDYATTKQITNTPAKESGVSFAPDNRTLVYASERTGNWQLYTAKIARKEEANFPNATL
                     IEEEVLLPSKTVERAYPQYSPDGKELAFIEDRSRLMVLNLKTKKVRQVTDGSTWYNTGG
                     GFDYEWSPDGKWFTLEFIGNRHDPYSDIGIVSAQGGTITNLTNSGYISGSPRWVLDGNA
                     ILFQTERYGMRAHASWGSQQDVMLVFLNQDAYDRYRLSKEDFELLKEFEKEQKKAKEKD
                     GDKKKDGSQSKKEKADKEKDKVDKEGDKEDTEKDKADKKDIVVELSGIEDRIVRLTPNS
                     SDLGSAILSKDGENLYYFSAFEEGYDLWKMNLREKGTKRLHKLNSGWSSLMLDKKGDIF
                     LLGSRNMQKMDAKSDALKSISYQAEMKMDLAAEREAMFDHVYKQHQKRFYNLNMHGVDW
                     NAMTAAYRKFLPHIDNNYDFAELLSEWLGELNVSHTGGRYSPRGNGDVTSNLGLLSDWN
                     YQGKGMQIAEIVEKGPFDHSRTKVKAGCIIEKINGEEITPDKDITDLLNNKAGKKTLVS
                     LYNPQNKERWEEVVKPVTSGQLNGLLYKRWVKQRAEDVEKWSGGRLGYVHIQSMGDGSF
                     RTVYSDILGKYNNCDGIVIDTRFNGGGRLHEDIEILFSGQKYFTQVVRGREACDMPSRR
                     WNKPSIMLQCEANYSNAHGTPWVYKHQNIGKLVGMPVPGTMTSVSWETLQDPSLVFGIP
                     IIGYRLPDGSYLENTQLEPDIKVANSPETIVKGEDTQLKMAVDELLKEIDSRKK"
     CDS             complement(9287..10213)
                     /locus_tag="ctg70_6"
                     /transl_table=11
                     /translation="MNFKDCIDSYPFILMEGALGERLKREFDLDISGTVAMADLVYQQK
                     GRLALETLWNEYIDIAYRYQLPFLATTPTRRANKERIYMAGYNESIIADNVDFLRSIKE
                     AANVDMYIGGLMGCKGDAYTGEEALNLEEAIDFHSWQAGLFKSAKVDFLYAGIMPVLTE
                     AIGMAVAMSDTDIPYIISFTIQRDGKLIDGHTIDDAIHCIDNHVSNKPVCYMTNCVHPD
                     IVYEALSHKFNQTQTVKSRFWGIQANTSQLSYKELDGANHLHTSSAADLSEAILKLKSD
                     CHLKIFGGCCGTDSSHMEKIAKISEVT"
     CDS             complement(10256..11077)
                     /locus_tag="ctg70_7"
                     /transl_table=11
                     /translation="MNYKITTLVENCVYGRKLQAEHGLSLYIETPENRLLFDTGASDLF
                     IRNARLLNIDLQKVDYLVLSHGHSDHTGGLRHFLELNAEATVVCKREVFFSKFKDEREN
                     GMKYTRSLDLSRFRFIDELTELVPGVFLFPSVDIIDPKDTHFERFWIQKEDGSRVPDTF
                     PDELAMVLVEPEGLSILSACSHRGITNILRTVRTAFPELPCNLLLGGFHIHNAEESKYQ
                     VIADYLHEYLPQKIGVCHCTGVDKYAFFYKDFGDRIFYNHTGKLIQTDSLL"
     CDS             11291..11440
                     /locus_tag="ctg70_8"
                     /transl_table=11
                     /translation="MEKEAKGKVNTVQIQYYQSPCGKLILGSFENKLCMCDWVVSEERR
                     AAID"
     CDS             complement(12032..12571)
                     /locus_tag="ctg70_9"
                     /transl_table=11
                     /translation="MAKKVLIISSSPRKGGNSDMLCDEFMKGVLETGNEVEKIFLKEKV
                     IHPCTGCSVCSMYGKPCPQKDDAAGIVEKMIAADVIVMATPVYFYTMCGQMKIMIDRCC
                     ARYTEITNKEFYFIIAAAENDKGMMERTIDGFRGFLDCLENPQEKGVIYGIGAWKVGEI
                     KDTPYMQEAYEMGKMV"
     CDS             12838..13527
                     /locus_tag="ctg70_10"
                     /transl_table=11
                     /translation="MKKIQLTNAHKEKLFQIPLFRDLPLNIKESLLDKLDFVIYAADKK
                     EIVVTQGTPCNKLYVLLEGKLRTDIIDGLGNEVMIEYIIAPRTFATPHLFNSNNTLPAT
                     FTALEDSVVLMATKDSTFKVISQDPQVLHNFLCIAGNCNICTVSRLKPLSRKTVRERFI
                     VYLFEHKKKDSLTVEIMHTQSQLAEYLNVSRPALSKEINKIIKEGLITMEGKKIEILNK
                     MALEKYL"
     CDS             complement(13617..13769)
                     /locus_tag="ctg70_11"
                     /transl_table=11
                     /translation="VMKDVKLSAGYSFMLGTKTMDAVKGGNHKSWQDWGWVSVNINPKV
                     FFTKW"
ORIGIN
        1 gagaattatc aaaacttaga aatgaattat acaaaacaac agtgttatta aaagaacatg
       61 cttttaatag tgaaaaagaa aaagaacaat taagtaactc tttggctgat atttcgcacc
      121 aattaaaaac tccattaaca tcaataagaa taatgcttga caatatttta gaaaatcctg
      181 aaatggataa agaagttaga gaagattttt taagagatat aagtagccaa atagaatgga
      241 ttagttcatt agttatatca ttactaaaaa tagctaaatt tgatgcagga acaataaaga
      301 tggaaaatga agaaatcaat gtgaagaaat taattgagaa tgttgcttca aatctatcca
      361 tattattgga agtaaaagaa gtacacctat atccagcgtc aattatgtgc taagcctgaa
      421 cagcccttta tcattaggaa cttgtacgtt tctgatcaat atgctgctta ttctgggaca
      481 gttctgggtc atcagaaaaa ataagacccg acaggacact attgaaatac ttcttcaatt
      541 gccgttctct tttatctttt cggcattcat tgattttaat atggcactca ccagtaatct
      601 gcatcccgac aattacggaa tgtcaatagc cttattactc acaggatgca tgatacaatc
      661 cataggagtc gtactcgaac tcaaacccaa agtagcaatg atgagtgcag aggcttttgt
      721 aaaatacgcc tcccgccgtt ataacaaaga gttcggaaag ttcaaagtct gttttgatgt
      781 tacgctggtc actctggcag tcatactctc tctcctgctt tcgcaatgca tcgaaggtgt
      841 tcgcgagggg tctcttatcg ccgcctgcat caccggatat atcgtcagct tcctgaatca
      901 gaaaataatg acaaggaaaa ctctctacaa attattacct gtattgaaat aagttttctc
      961 tagctcgcta ccagcaacgt ttccatctgc ctgacgatat aaggtttcca ctgaaccaga
     1021 atatcctcaa aagaatcatc cttctccaaa aagaaagaag cactgagatt ctttgtcagg
     1081 aaaggaactg tcaatgcact ataaaaagta tagaatacga atggcaaagg aactgttttc
     1141 agtctcccgt cattcatttc ttcctgtaaa acatccatga ttttatggag atattgttcc
     1201 aggcgcaact ccttgatagt agtgcttaaa tggttcatat cacgatgcat ctccctcacc
     1261 atgaacaatg gcaaacatgg attttccgtg aatactttat aataagcatc tacaatttca
     1321 ccgatactct cggagacagg tttgtcctgc tgaatgatta tatcatgtat tttgggaata
     1381 aaagaaagta tgatattacc aaaaacggcc tgaaacatct tatccttcgt tcggaaataa
     1441 tagtgaagtg ccggtctgtt gatacctact ttagcagcga tatcactcat actggtttct
     1501 gcgaacccat tctctataaa tagttctttg gcagcctcaa ttatcttttt ctccaaatct
     1561 tcattattat tagttgttgt cataattcat tgtcgcattt ttcagattat caataaacaa
     1621 aagcatacgg tttgttatgt ttacgtcgct cacaccacta tcaaagtcta aagatagcaa
     1681 atttatatcc ggatagaaac tttttatacg tttttcgact cctctggata cgatatgatt
     1741 cgctatgcag ccaaaaggtt gcaaactcac tacattgttc accccttgcc gggcgtaaga
     1801 cacgatttca gccggcaaca accagccttc accgaattgg gcattcagcg aaataacgct
     1861 tttagctcct tccgcttctt caaagatatc attgaagggg gcaaagtaac ggaacttact
     1921 tgctgtctca tttattttat caatctgttt ctttacaaac ttgtagatcc agtcgtaaat
     1981 aaactcaggc aactgtctgt tttttatgta agaatccgta ttgactttcc tgttcacaaa
     2041 cccctgcatg aaaaagtcag ccagaatcgg cggaaccact tctatcttgc ggcctatcag
     2101 ccaatcaatg atctcttttt gtgcgaaagg attgaatttc aagaagattt ctcctacaat
     2161 tccgacttta ggagtatcta cagccctaca tacctcatta aattcagtga ttgccgattg
     2221 caacaaagag ttcaacccct ttatgtctct tctcagtatc acttcaggtg ccagttgcag
     2281 gtatttatca cgcagctttg ccgatgcacc tgcttctttc tcacgtacca cagacgcata
     2341 ataaaactta gcaatgcaat cactatacaa aacggcatga aaagttatcg gtactacttt
     2401 catccagttg accttgaacg cgggctggtc attatctatg tcactgccca cagagataga
     2461 gattaccgga atatccgtat atccggcatc caccaacgcc ttttttatca aggaaatata
     2521 gttgctggca cggcattgtc ctcccgtttg ggtgatggct acggctattt ttgaaatatc
     2581 atatttcccg cttttaagtg cttttataat atcgccgact atcagagtag ccggataaca
     2641 gacctcatta ttcgcatact tcaaccccca ttcacttgaa tcattatcac tgagaggaag
     2701 gttttccgca tcataaccgg ctactttcat aatagcagga atcaaaggtg aaataaacgg
     2761 agtaaagtaa ggaacgagta tcttacggtc acggtaagac ttgtcataaa caggaacggt
     2821 cgtaaagtcc tttacaccgt cttccgttcc atccgcattc gcaagtttga ggctttcaat
     2881 catggaacgt actctcaact tcattgaacc gatattattg atatcatcca gtttcaataa
     2941 ggtcagcgat ttgttatgac gcatcagcaa atcccttact tcatccacca gaaaagcatc
     3001 cggtccacat ccgaacgaag tcatctctac aaactgaata ttctttcctt gtgtcgcaca
     3061 ccatttcgca gccttcagga tacggttcgt atacgcccat tgagcaacaa aatgcgcatc
     3121 atccgtcggt atatccatct gacgcaccaa atcatccgct atcacattca ctcccatatc
     3181 cgcaagcata tccgagactt tgtgctgtat cagagaatcg gtatgataag gacgtccggc
     3241 aagcatgaca gtcaaagtct ctccctttcc agtctgctgc aatatgtttt tgttataatc
     3301 gaccaatgta ttaataaaag agtgctgttc gctttccgct ttttggaatg cttgctgaat
     3361 cgtccgatcg tccacgctca aaccgctcag atattcacgg cattgtttaa acaacagatt
     3421 ccggtctttg aaagttattg caggggaatc aaccggtata ccttcggact gcacactttt
     3481 gataacctcc gaataacctg tcacaatcgg acaattataa ctgttttgtt ccatcccttt
     3541 tctttcgaaa ataacaaaag gcataaaaat ccggtcgacc ttcttttcta tcaagtcctg
     3601 aacatgacta tgtaccagct tagccggaaa gcagatattg tccgacatca ccatacgcgc
     3661 attgtgctca tactttctga aattggacgg atcagacaaa cagacttgta tgccacagga
     3721 agtgaaaaga gtgtgccaga atggatattc ctcgtacata ttcagacatc gggggattcc
     3781 gataatctgc tcgggtgctg caatctctgc gctgcgatga aacaaaagct cttctttttg
     3841 ccgatagaca ttcagacctt tccggttact gctctctcca ttcgtgaaaa ctttctcgca
     3901 cctgtttccc gaataataac ttttgccgct ttcgaactcg taacgaatga ccagacaacg
     3961 attatcgcaa ctcttgcaat ataaagaacg tgccgaatat tgagctttat tgataatctc
     4021 atccaatgat acggactccc cctgatgttt catcgcatat aatgcacatc cgaatgctcc
     4081 catcaattcg ggtgtatcac accttgccac ttccgctccc gagagaagtt caatggcacg
     4141 gaccaccgca tcattgcgca tggtgcctcc ctgcacaaca atatcttttc ccaaaacaga
     4201 tatatctttc agtttcaaca ccttatacag gcaattcttg acaacggaat atgccagtcc
     4261 ggcggcaata tcattgatcg ttgccccctc cctgagtacc tgtttcactt ttgagttcat
     4321 aaaaacggtg caccttgttc ccaaatcaca cggtgcttcc gaatggcagg ctgccagaga
     4381 aaactcttgt gccgaatacc ccagagattt agcaaacgtt tcaagaaaag aaccacatcc
     4441 ggaagagcat gcttcattaa tctccatccg gtcaatcacg ccattattca caaaaataac
     4501 cttcatatcc tgtccgccga tatcgaggat aaaagacaca tccttgttca gataatgcgc
     4561 tgccatataa tgggcgatcg tttcgataat ccccgaatga agctgaaagg cagacctgat
     4621 aaggtcttcc ccatatccgg tagaacagct tccttttata ttgagtacgg cattctgctt
     4681 caaacattca tcgttcaact gattcagccc ctcttccaca gcttttatcg gattgccgcc
     4741 attaatatta taataagaat acagaagcct tgaatcttca tccagtacaa caatctttgt
     4801 cgtagtagaa cctgaatcga tgccgataaa gacatcctgt gttccggctt tcaagccgga
     4861 agatatcatc ttatgacggg atattctttc tttccatgct tcatattctt cattacttgc
     4921 aaaaacaggt tccaatcctg ttgaggcaag gttaccgtta ccgtttaaag tagtgtcaat
     4981 cttatcgatc aaatgggaca gtttacagta atcctcttta tcaagatgaa atagagcagc
     5041 acctagtgca gggagcaaag tgccgttggc cggcagtatg atctcttttt catcgaggga
     5101 caaataatca atgaaggctt tccgcagtgc cggaatgaag gttaacggac caccacaaaa
     5161 caatacggga gttgtaatat cgcaaccgtg cgccagcgtc actaccgttt gaactgctac
     5221 cgcacgaaag atggaagccg caatattctc acgacttaca tttttagcta tcagattctg
     5281 aatatccgtt ttacagaaaa cgccacaacg ggaggcaata ggatatacct gtgtcgcatt
     5341 catggctagt tgattcaatt catcaatatt cactcccagt ataatcgcca tctggtcaat
     5401 aaaagcaccc gtccctcctg cgcaattgcc gttcatacgc aaatcggtcg cttcggcatc
     5461 attaaagaag acgactttcg catcttctcc tccgatgtct atcatggaag tcacatgaga
     5521 ataatccttt tgtatcgctt tcgctgccgc aacaacctcc tgtacaaacg gcaacgaaca
     5581 tttctctgaa attcccattc cgatagagcc tgttatcctc acggaaatat ctttatctcc
     5641 gatttcagat aacagctctt tcaagaatga tagaattgtc tcttttgctt tcgcattgtg
     5701 tctctcgtac tttgaaaata atagattatc attttcatcg acggcaacta acttcgccgt
     5761 cgttgaacct acatcaattc ctattttaat catgttctac actatgttcc cctagtttga
     5821 cactattgtc aaacacaaaa gtaagaataa gttggacaca tcatttcaat aagctttttt
     5881 ttcggttctt ttaacacaaa cgaacgatgt ctatttcttc cgactatcta tttctttaag
     5941 caattcatcc acagccattt taagttgcgt atcctctcct ttcactatag tctccgggct
     6001 gttggcaacc ttgatgtcag gttccaactg agtattttcc agataactgc catccggtag
     6061 acgataaccg atgataggaa tcccaaatac caatgaaggg tcctgcaaag tttcccaaga
     6121 tacacttgtc atagttcccg gaacaggcat acctaccagt tttccaatgt tctgatgctt
     6181 gtacacccac ggggtgccat gcgcattcga ataattggct tcacactgca acataataga
     6241 aggcttgttc cagcgacggc ttggcatatc acaggcttca cgtccgcgta ccacctgagt
     6301 gaaatatttc tgaccgctga aaagaatttc aatatcttca tgcagacgac cgcctccgtt
     6361 aaaacgggta tcgatcacaa ttccgtcaca gttattgtat tttcccagaa tatccgagta
     6421 aacagtacgg aaactgccat ctcccataga ttgaatatga acgtatccca aacgaccgcc
     6481 ggaccatttc tccacatcct cagcacgttg ctttacccaa cgtttatata ataagccatt
     6541 aagctgtccg cttgtgacag gttttaccac ttcttcccaa cgttccttat tctgcgggtt
     6601 gtacagcgaa accagtgttt tctttcctgc cttattattc aagagatcag tgatgtcctt
     6661 atccggagtt atttcctccc cgttgatctt ttctataata caccctgcct ttactttggt
     6721 acgggaatga tcgaacggcc ctttctctac gatttcagca atctgcatac cctttccctg
     6781 ataattccag tcagacaata agcccagatt agaggttaca tccccattgc ccctcggaga
     6841 atagcgccct ccggtatgcg aaacattcag ttcacctaac cattcgctca gtaattctgc
     6901 aaagtcatag ttattatcaa tatgtggcag gaatttacga taggcagctg tcatggcatt
     6961 ccagtccact ccgtgcatat taagattgta gaaacgtttt tgatgttgtt tatatacatg
     7021 atcgaacatt gcctcacgtt cggctgccaa atccattttc atttcagcct gataactgat
     7081 agatttcaga gcatccgact tcgcgtccat tttctgcata tttctgcttc ccagcaagaa
     7141 gatatctcct tttttatcca gcatcagtga tgaccagccg gaattaagtt tatggagacg
     7201 cttcgtccct ttttcacgaa gattcatttt ccaaaggtca tatccctctt cgaaagcaga
     7261 gaaataatac agattttctc catctttgga aagaatagca ctacctaaat cagaagagtt
     7321 aggagtcagg cgtacaatac ggtcctcaat accgctgagt tccacaacaa tatctttctt
     7381 gtctgccttg tccttttcgg tatcctcctt atctccttct ttgtctacct tatctttttc
     7441 tttgtctgcc ttttcctttt tagactgact tccgtccttt ttcttatcac cgtctttctc
     7501 ctttgctttc ttctgctcct tttcaaattc tttgagcagt tcgaaatcct ctttactcaa
     7561 acggtaacgg tcgtaagcat cctgattcaa gaataccagc atcacatcct gttgtgatcc
     7621 ccaggaagca tgggcacgca taccataacg ttcggtctgg aacagaatgg catttccatc
     7681 cagtacccaa cgtggagagc cgctaatata accactgtta gtcagattag tgatagtacc
     7741 tccctgcgca ctgacaatgc cgatatccga atagggatca tgacgattgc cgataaactc
     7801 aagcgtaaac cacttgccat cgggcgacca ttcgtagtcg aatccgcctc ctgtattgta
     7861 ccatgtagaa ccgtctgtca cctgacgtac ttttttagtt ttcaggttga gtaccatcaa
     7921 ccggctacgg tcttcgataa aagccaattc cttaccatcc ggagagtatt gcgggtaagc
     7981 acgttctacg gttttagagg ggagcaatac ttcctcttca ataagagtgg cgttagggaa
     8041 attcgcctct tctttacgag ctatcttagc ggtataaagt tgccagttgc cggtccgctc
     8101 gctggcataa accagtgtac ggttgtcggg agcaaaagat acaccggatt cctttgccgg
     8161 agtatttgtt atttgcttgg tcgtagcata atcggttgaa gtcacaaaaa catcacctcg
     8221 cacaataaaa gccacctgct tgccatccgg agacacagaa gcagaagtcg caccctgaga
     8281 aaatctgaga gtagcaatct ctttttcatc atcatgcaca agatcaacat ttactttctt
     8341 cgggcgggca ttgggctctt gtgtataaag ttctccgtca tacgtatagc ataaagttcc
     8401 tttatcgctg attgacaaga aacgtaccgg atgcgtgcgg aaagtggtga tggctttcac
     8461 ttcctgcgga gtgttcaggg caaagttata tacattaaat gaaccgccat tgcgctcact
     8521 tagaaaatag accgaattac catccggtgc atataccgga ttacggtctt ctccttcccg
     8581 attggtcaga ttggtatgtt ttccggtcga agcatcgtat agccaaacgt ctcttgttat
     8641 agatgaggta tggtgttttc tccattcatc ttcaaaacct ttacggtcct gataaaggaa
     8701 gttttttccc gatttatcaa agcataccca ttcggcagga gtagccaaca cttgttcggt
     8761 acgtcctccg gtaaccggaa ctttatataa ttccgtcatg gctccggtag gaaaaagggc
     8821 actttgcgca gggtcctgaa tggaggcgga gaaaagtaca aatttaccat ccggagtgaa
     8881 agccgaagga atctccgagg cagaatgata agtcaaccga cgtgcagttc ctccatcggc
     8941 agacatgata aagagatcga agttcccatt ccggtcgctg gcaaacgcga tttgtttacc
     9001 atctggcgac cagacgggat tagcctcata agaagcttgt gttgttaatt gggtagcggt
     9061 tcccccttga acggggactt tgtaaatgtc gcctttataa caaaagacga tttcctttcc
     9121 gtccggtgag atacgtgcat cacgcatcca caaaggggta atagcatagc tggataatgc
     9181 agtcagtacc agcgctaaag agatgattat tttcttcata ttattgtatg tttatatatt
     9241 tattctatat tccttgtttc atgagaagac cgtatttcta gttagtttaa gtcacttccg
     9301 atattttagc gattttttcc atgtgactgc tgtctgttcc acaacaccca ccaaatattt
     9361 taagatgaca atcagatttc aactttaaaa tagcttcact cagatcggct gccgaagaag
     9421 tatgtaaatg atttgctcca tccaattctt tatatgacaa ttgggaagta tttgcttgta
     9481 taccccaaaa gcgagatttt accgtttgtg tttgattgaa cttatgagaa agtgcttcgt
     9541 aaacaatatc aggatgaaca caatttgtca tatagcacac aggtttgtta gacacatgat
     9601 tatcaatgca atgtatggca tcatcaatgg tatgcccatc tatcagtttt ccgtctcttt
     9661 gaatcgtaaa gctgataata taaggaatat ccgtatcaga catagcgact gccatcccga
     9721 tagcttccgt caatacaggc ataatacctg catataaaaa atcaactttg gcagatttaa
     9781 acaaaccggc ctgccaacta tggaagtcta ttgcctcttc cagatttaga gcctcttcgc
     9841 cagtgtatgc atctccctta catcccatca aaccaccgat atacatatct acatttgctg
     9901 cttcttttat ggaacgaaga aaatccacat tatctgcaat aatggattca ttgtatccag
     9961 ccatataaat ccgttcttta ttggcccttc ttgttggagt tgttgcaaga aatggtagtt
    10021 gatacctata tgcaatatca atatattcat tccatagcgt ttctaatgcc agtctacctt
    10081 tctgctgata gactaagtca gccattgcaa cagtaccact gatatccaaa tcaaactccc
    10141 tttttagtcg ctcgcctaaa gcaccttcca ttaatataaa gggataagaa tctatgcagt
    10201 ctttaaaatt catccagttt gtttttatat attcttgttt agtcgtcgca gattattata
    10261 acagagaatc cgtctgaatc aatttccctg tatggttata aaatattctg tctccaaaat
    10321 ccttatagaa gaaagcatat ttatctactc ccgtacaatg acagacacct atcttttgag
    10381 gtaaatattc gtgcaaataa tcagcaataa cctgatattt ggattcttct gcattatgaa
    10441 tatgaaatcc acctaaaagc aaattacagg ggagttccgg aaatgccgtt cttacagtcc
    10501 gcaatatatt tgtaataccc cggtgggaac aggcacttaa aatggaaagt ccttcaggct
    10561 caaccagtac catagctaac tcgtccggaa aggtatcggg gactctagaa ccatcttcct
    10621 tttgaatcca aaatcgttca aaatgtgtat ccttcgggtc tataatatcc acagagggaa
    10681 aaagaaatac tccgggaacc agttcagtca actcatcaat aaaacgaaaa cgagaaagat
    10741 caagcgagcg tgtatatttc attccattct cacgttcatc cttgaattta gaaaaaaaca
    10801 cttcgcgttt gcagacaacc gttgcttcgg catttagttc aagaaaatgg cgtagtccac
    10861 ccgtatggtc actgtgacca tgagataata ctaaataatc tactttttgc aagtcaatat
    10921 tcaataaccg ggcgttacgg ataaataaat cggaagctcc cgtatcaaaa agtaatctgt
    10981 tttccggtgt ctcaatatag agggaaagac catgttctgc ctgcaattta cgtccataga
    11041 cacaattttc gacaagagtc gttattttat agttcatgtg gtttggttct ttatcaaata
    11101 ctacgaaata aaaagttctg ctacaaaatt ataataattc tacggcagaa caagtaatca
    11161 atcaatttaa atcgactgta agggtaaaag attttgtttc aggcttctat tgccgaatta
    11221 ttcattttgt agtttgaata caaataatta cttttacatc catatcaaac cctttaaata
    11281 aagaatcaaa atggagaaag aagcaaaagg taaagtaaat acagttcaga tacagtacta
    11341 tcaatctcca tgcgggaaat tgatactcgg ttctttcgag aacaagctct gtatgtgcga
    11401 ctgggtggtg agtgaagaac gcagagcagc aatcgattaa cgaatacaaa aagcgctaaa
    11461 tgctcagtac gcaatagaaa actctgaagt gataacgcaa acgatcagcc agctagatga
    11521 gtatttttcc cgtcaaagga ctacgtttga tattcctctg cttcttgtcg ggacagagtt
    11581 tcaaaagagt gtatggaatg aattattaaa cattccctac ggaacaacga tatcttatgc
    11641 tcaattatca cagagactgg ataatcctaa agctatccgt gcggtagcct cttcgaatgg
    11701 agcaaattcg atttcaatac ttattccttg tcacagggtg atcggcagtg atcataaact
    11761 gaccggatat gccggtggtc ttgtagctaa aaagacttta ttggagctgg aatcgaacga
    11821 aagaagatta ttgtaacaga atcgttaaac taaacttctc tcattaaatc cagacaaaaa
    11881 tatggtgtca ctatcccatt actatagtgt cactatcata ctgctttagt gtcactatcc
    11941 tacaggtata gcgtcactat atactcagca tagtgacacc atcctgaaag gttgttatat
    12001 aagacgggaa atgtttacct aaagcgaacg tttacaccat ttttcccatc tcataggctt
    12061 cctgcatgta gggagtatct tttatttctc ctaccttcca ggcacctatt ccataaatca
    12121 ctcctttttc ctgcggattt tccagacaat caaggaagcc acggaaacca tcaatcgtac
    12181 gttccatcat ccccttatca ttctccgccg ctgcaataat gaaataaaat tccttattcg
    12241 ttatttccgt ataacgcgca caacaacggt caatcataat cttcatctgt ccgcacatcg
    12301 tatagaaata aacaggtgtt gccattacga tgacatcagc agcaatcatt ttctctacaa
    12361 ttcctgcggc atcatctttc tgggggcagg gtttgccata catgctgcaa acactacatc
    12421 ccgtacaagg atgaattact ttctctttca gaaaaatctt ttctacttca ttgcctgttt
    12481 cgagaacacc tttcataaat tcgtcacaaa gcatatcaga attaccgccc tttcgggggc
    12541 tggacgaaat aatcagaact tttttagcca taactttatt acttttattt tttgaatttc
    12601 attaatcagc tttttcactc tgcaaaaata gacaatttat catatagcaa atgtagataa
    12661 attacagaga tgtgtaccct aattactgat tcaaacattt tctgccattt ttacttttta
    12721 tcaatatcct tttcatctca tccataatcg gtctttcggc ggcacaaaca taaaaaaaga
    12781 ttttctctgc ccatatataa ttcatatctt tgcccatgat acgaacaaca taatgcaatg
    12841 aaaaaaatac aactgaccaa cgcacataaa gaaaaattat ttcaaatccc tttatttcgg
    12901 gatttacctc tgaacattaa ggaatctctg ctggataaac tggatttcgt tatctatgca
    12961 gcggataaaa aagaaatagt tgttacgcaa ggtacacctt gcaacaaact atatgtgtta
    13021 ttggaaggaa aactacgcac ggatatcatt gacggattgg ggaacgaagt gatgattgag
    13081 tatatcatcg caccacgtac ctttgccacc cctcaccttt tcaattcaaa caatacgttg
    13141 ccagctactt ttactgcttt ggaagacagc gtggtactca tggcaaccaa agattccact
    13201 tttaaagtca tcagtcagga cccgcaggtg ttgcacaatt ttctttgcat cgccggaaat
    13261 tgcaatatat gtaccgtatc acgtttgaaa cctctgtcgc gcaagactgt acgcgaaagg
    13321 tttattgttt acttattcga acataagaaa aaagattctc tgactgtaga gatcatgcat
    13381 acccagtcac agcttgccga gtacctgaat gtatcacgtc ctgctttatc caaagaaatc
    13441 aataagataa tcaaggaagg gctgatcaca atggaaggaa aaaagatcga gattctgaat
    13501 aaaatggcgc tggagaaata cttataataa aaagaaagtg gcacagccta aatttaatgc
    13561 tgtgccactt tttatattct atcaacggtt taatctgaat cctagctagg tttcaattac
    13621 cattttgtaa aaaacacttt cgggttgata ttgacagata cccatcccca gtcttgccag
    13681 ctcttatgat ttccgccttt cacagcatcc atcgtcttcg ttccaagcat aaaagaataa
    13741 ccggcagaga gtttcacatc tttcattac
//
