LOCUS       gnlProkkaOELEJGKM_662  10869 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OELEJGKM_662.
ACCESSION   gnlProkkaOELEJGKM_662
VERSION     gnlProkkaOELEJGKM_662
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-18 09:22:36
            Original ID  :: gnl|Prokka|OELEJGKM_662
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10869
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..315)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg662_1"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 3.6e-33,
                     bitscore: 104.5, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVFKDKVLLITGGTGSFGNAVLRRFLDSDIKEIRIFSRDEKKQD
                     DMRHHLQNPKVKFYIGNVRDRQSVDGAMMGVDYVFAAAALKQVPSCEFFPLQAVQTNVI
                     G"
     protocluster    1..10869
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[2300:5869]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2301..5869
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..10869
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10869
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             complement(330..1445)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg662_2"
                     /sec_met_domain="Glycos_transf_1 (E-value: 5.9e-13,
                     bitscore: 38.5, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNILINCSNLKKGGGLQVADSVCSCLNTIPQHDFFLVLSSCMDDT
                     ADRVSEYKNVTVVRHDIRNSWYTLFWGRDKAMDNLVTRHNIGGVLTIFGPARWKPKCKH
                     LCGFARSHLVLNDSPYFQRMSWKELMIEKARNLYLYYYFKRGVTAFWTENPYISEKVKH
                     LFPTIKAYTVSNYYNQVFDDENTQIEHALPSFDGCTLLSINAPYPHKNLAIAIEVARYL
                     KKHYSEFSFRFVFTVTENDLPPIPSYLREHFCLIDKVSVAECPSLYRQADIMFQPTLLE
                     CFTATYVEAMRMQVPILTTDLPFAHGLCGNAAVYYSPLDAEDCAKSIYKMAVDTSFQDY
                     LVGEGIKQLKSFDNYNRRAEKLIDLISNLDD"
     CDS             complement(1600..2316)
                     /locus_tag="ctg662_3"
                     /transl_table=11
                     /translation="MSRGISEKEQRWLLVLSQVIEVLDKNNLLYFIDTGTLLGAVRDKM
                     FIPWDNDIDLAVIGGDTSTTNLLKVSKLLYALGFYVTLTKKEIAICSRDGVNLGIKLYK
                     KQASHYEACMGKVYRHRLFYSINLYLSGEVLYKKGFSFKYKAISLFVKFSQVFKLKLSC
                     IWQMKLLFWAKYDEKTVIIPFEFVDAIIDYNFYNIIVKVPNKPERYLAYRYGENWKVPK
                     QDYDYMIDDKSIINID"
     CDS             complement(2301..3395)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Fe-ADH"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg662_4"
                     /sec_met_domain="Fe-ADH (E-value: 1.5e-76, bitscore: 247.2,
                     seeds: 218, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEQRFFLGESSIKELIPILQEYTPDHIFLVRGKKSYEKCGAQAVL
                     ESVFVKLACGVTEFFDFEANPKIEDMEKGLSLLKEYPTNMIIAIGGGSVLDMAKLLRFF
                     YSYSGNPTGGEFEKKRQLIPLITLPTTAGTGSEATHFSVLYKDKVKYSVEHDAILPDVA
                     IVYPKFTYGNSKYLTSCTGFDALAQAIEAYWNVNATEESDKYAAKAIKLLWPNLPLVVN
                     SPTAEARNKVSEGSYWAGRAINITKTTAPHAFSYSFTTDYGYPHGHAVALTFPFFMRYN
                     IGNSDILLNPNINPYLYKIKMQKMLQWLNMECVDVAIAMKEYIRNLGLDIDISQIDISK
                     IVSSVNIQRLINNPYKVEAICLEE"
     CDS             complement(3403..4533)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 69;
                     E-value: 6e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg662_5"
                     /sec_met_domain="TPP_enzyme_N (E-value: 1.8e-17, bitscore:
                     53.2, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.9e-21, bitscore:
                     65.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISPNIFVDSLGAMQMDFFTGVPDSLLKNICAYLTDHLASEHNII
                     AANEGAAIGLATGYYLATRKIPVVYMQNSGLGNAVNPLMSLTDKEVYNIPLLLLIGWRG
                     EPGVKDEPQHIKQGKVTLPLLEAMGIRYAVLSQDEKKFISQLNVAKSYMDETREPFAFV
                     IQKDTFLEYSSENCEDERLSLKREAAIHFIAASLTEKDIIISTTGMISRELFEYRESTS
                     LEHERDFLTVGSMGHASQIALGIALKKRDCKVYCFDGDGSTLMHMGSLAIVGSLHPENY
                     VHVVFNNGAHDSVGGQPTVALDIDLCKIAQACGYEIVLSVSDNEGLCEALKKIQQIRGP
                     ILLEVKVRKGARKNLGRPANTPIQNKEAFMLFLDNL"
     CDS             complement(4565..5869)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 202.6;
                     E-value: 1.3e-61)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg662_6"
                     /sec_met_domain="CTP_transf_like (E-value: 3.1e-13,
                     bitscore: 39.8, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 8e-120, bitscore:
                     388.9, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 2.7e-64, bitscore:
                     206.6, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKKKVYVGMSADIIHPGHLNIIHEASKLGHVTVGVLTDSAIASY
                     KRLPYLNFDQRSLIVLNLKGVDEVIPQTTLDYVPNLELIRPDFVVHGDDWKEGIQQETR
                     QRVIDTISKWGGKVIDVPYTKGISSTLLNTRLKEIGTTPEIRLKRLKRLIAAKSIVRIC
                     ESHSGLTGLIIENTSVEVNGVKREFDGMWSSSLTDSTSKGKPDIEAVDLTTRLHDLNDA
                     LECTTKPVIFDGDTGGKIEHFVFTVRTLERLGISAVIIEDKIGLKKNSLFGTDAVQTQD
                     TIEGFCDKIQAGKRAQITDDFMIIARIESFIAGKGLDDALGRALAYIKAGADGIMIHSK
                     DKSGEDIKNFCLALRKIHKSIPIVVVPTTYNHISEDELASWGVNVVIYANHMLRSAYPA
                     MLNTAKSILANARSYEANDLCMPIKEILELIPGTK"
     CDS             complement(5832..7211)
                     /locus_tag="ctg662_7"
                     /transl_table=11
                     /translation="MIAIIFLILFLIQILISNRLIIDSFSRKISFIYLLWWGTAIVIST
                     FDPAELYSVSMKTYMLLLINVWAFNWGFLCFGKIKKIRLKVTTDNSFYNLVIGNNKMIL
                     LLMLACIVTYYYAMKFALVIELYGAGEGRMMRFEAGELFTSNLEVYLYDFLIKPFTQFV
                     MLIVACMLLSKIKRRILLLSVLFLFLYASVGNGRGGLIVFLFYCFIIYYLRRELYYINL
                     LASKRKKWNFGVVSFVCLFVGVGIIVVVISYMTAQRMGFDTFSAEVVKIGFEELKSQAV
                     WYFLGPFRALDYSFRANYESITGFWYGRATMGGIDNLLKLVIHYLGGSYTIAHDEIGHL
                     LQNSKISVGNGIIFNYAYTNIIFHYLDFGYVGVLLFPFLYGFIVRYSIYKFTQKPTLLT
                     LGIMIYLVYISMFNIFSWEFQKPSSIIYVLLLLFFQYVYSHKFVILKLNGKKKGLCRHE
                     C"
     CDS             complement(7208..8140)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg662_8"
                     /sec_met_domain="Glycos_transf_2 (E-value: 6.9e-26,
                     bitscore: 80.8, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNGSITVSICCLTYNHEKYIRQCLDGLIMQKTEFDFEILVHDDAS
                     SDATQSIINEYVVAYPNLIKPILQIRNQYSQGISPLRQILFPLVKGKYVALCEGDDYWT
                     DPLKLQKQVNAMESDHSLAGCAHQSLVFYENGTPSHMFHHVKKQILKTKDLLDVRLFHT
                     ASFLFKKEVLDYIKDFNSSLYAGDRFLFLACSLKGNILYMPDVMCCYRKNAMGVTSRVS
                     YSLHVLDLKVPEYFHNKDLKFPYYRYLAFVHRAIFSESLDISLKKYIYHFTLFVKYSFS
                     YFPKNLKDIYKALYVSFWWLTKGQKYRIK"
     CDS             complement(8141..9136)
                     /NRPS_PKS="Domain: NAD_binding_4 (91-233). E-value: 3e-07.
                     Score: 21.7. Matches aSDomain:
                     nrpspksdomains_ctg662_9_NAD_binding_4.1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score:
                     114.5; E-value: 1.1e-34)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg662_9"
                     /transl_table=11
                     /translation="MKKKIIIFGATGNTGSYLLEYALNFFNKEEYEIIASGRRETTFFS
                     KRGIPYYSVDITKEEDFDKLPMENIHAVMLLSAQIPSYMDTYCPIKYLDSIVIGGFNVL
                     EYCRKCHVDRIIYTQTVFDISLYSHDTILKPDMKPNFSYTGDHAIYVISKNTALDLIEH
                     YYQEYGLKKFIFRLPTIYSYSPYPYYFPNGVKTKRPIYQMIENAQKGLPIEIWGDPHYA
                     KDMVHVNDFSQMLCKAVEVEQESGFYNVGTGMPITLEEQIRTIISVFSPKESPSEVIYR
                     PDKVCGGGYIMNIENAKKELGYVPQYDCRKLFEDYKSEMEIKRFAELRLK"
     aSDomain        complement(8438..8863)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg662_9_NAD_binding_4.1"
                     /evalue="3.00E-07"
                     /label="ctg662_9_NAD_binding_4.1"
                     /locus_tag="ctg662_9"
                     /protein_end="233"
                     /protein_start="91"
                     /score="21.7"
                     /tool="antismash"
                     /translation="YLDSIVIGGFNVLEYCRKCHVDRIIYTQTVFDISLYSHDTILKPD
                     MKPNFSYTGDHAIYVISKNTALDLIEHYYQEYGLKKFIFRLPTIYSYSPYPYYFPNGVK
                     TKRPIYQMIENAQKGLPIEIWGDPHYAKDMVHVNDFSQ"
     CDS             complement(9133..10098)
                     /locus_tag="ctg662_10"
                     /transl_table=11
                     /translation="MMSIGGYFELEIREGEHFHQGAIKLSTARQCFEYILKARRYTKVY
                     IPYYTCDVIIEPLMKLNVKYEYYHINSLLDPVFDKKIESSEAFLYTNYFGLKQDTVLYL
                     SRFYPNLIVDNAQAFFAKPIEGVDTFYSARKFFGVPDGAYLYTTALLDIDFPIYNPIDN
                     INYLIGRITDSAEGYYKDFQESEERMSNQEIHRMSVLSDKILSSLDYVSIIERRRFNYH
                     LLYSALTAFNKFDFSISENQNVPLIYPFYTSKAGLRQQLILEHVYVPQYWQNVVNKIDA
                     KCLEYSIANNMIALPIDQRYDEKTMNILIEKISNLNNHLS"
     CDS             complement(10095..10784)
                     /locus_tag="ctg662_11"
                     /transl_table=11
                     /translation="MKLGIMQPYFMPYIGYFQLIKAVDKYVVYDDVNYIKGGWVNRNNI
                     LVNGEKKMFTITLKGASAYKHFNEIEIGDDFRKFMKTLELNYSKAPFYHETMELLYRII
                     MFPNRQLALFLANSFKEILDYLNIQTEILLSSDLPKDCSLKGKDKVLHICKLLSADTYY
                     NAIGGKQIYNKEDFMQNGINLKFVDTIIKRYPQQSKEFVPYLSIIDVLMNNSKEETCML
                     LDSFSLQ"
ORIGIN
        1 accgatcaca ttggtctgca cagcctgcaa cgggaagaac tcgcaactgg gaacctgctt
       61 caaggcggca gcggcaaata cataatccac tcccatcatg gcaccgtcta cagactggcg
      121 gtcacggaca ttaccaatgt aaaattttac tttgggattt tgcaggtgat gacgcatgtc
      181 atcctgcttt ttctcgtcac gactaaaaat acgaatctcc ttgatatcag aatcaaggaa
      241 acgacgcaat acagcgttac caaaactgcc ggtacctccg gttataagga ggactttgtc
      301 tttaaatact gacataaata taatatgtat taatcatcca aattcgatat caaatcgatt
      361 aatttttctg ctctccgatt ataattatcg aaggacttaa gttgttttat tccttctccg
      421 accagataat cttgaaagga tgtgtctaca gccattttat aaattgattt ggcacagtct
      481 tctgcatcta acggcgaata gtacacagct gcatttccac ataatccatg agcaaatggc
      541 aaatctgtag ttaaaattgg cacttgcatt cgcatcgctt cgacatatgt ggcagtgaaa
      601 cattcaagta aagttggttg aaacattata tctgcctgac gatataagga agggcattct
      661 gctacactaa ctttatcaat cagacagaaa tgctctcgca aataagaagg aataggtggc
      721 aagtcattct ctgtcaccgt aaaaacgaat cgaaaactaa attcggaata atgtttttta
      781 agatatcgag cgacttcgat agcaattgct aaattcttat gaggataagg agcatttatg
      841 gacagtaaag tacaaccgtc aaaagacggt aaggcatgtt ctatttgagt attttcatca
      901 tcgaaaacct gattataata attcgataca gtataggctt ttatggtagg gaacaagtgc
      961 tttactttct ctgaaatata aggattctca gtccaaaaag cagtcacacc acgtttgaag
     1021 taataatata aataaagatt tctcgccttt tctatcatta gttccttcca agacatacgt
     1081 tgaaaatagg gagaatcgtt caaaacgaga tgggatctgg caaatccaca tagatgctta
     1141 catttcggct tccatcttgc aggtccgaat atggtaagaa ctccaccaat attgtgtctg
     1201 gttaccaaat tatccatagc cttatcacgt ccccaaaaca atgtatacca actgtttcgt
     1261 atatcatgac gcactacagt gacatttttg tattccgata ccctatcagc agtatcatcc
     1321 atacatgagg ataatactaa aaaaaaatca tgttggggaa ttgtattcaa acaagaacaa
     1381 accgaatcag cgacttgaag ccctccacct ttcttgagat tggagcaatt tattagaatg
     1441 ttcatttgtt ccgagaatat aatatataag tgcccaattt tggtgtataa atgaaagtgc
     1501 tatttataaa taccatctat attgtctaaa gaaaaagttg attataattt tattaattac
     1561 aataatactc cttatgttga aatttgtttt catatttttt taatcaatat ttataataga
     1621 cttgtcatca atcatataat catagtcttg tttgggaacc ttccaatttt caccatatct
     1681 atatgctaga tatctttctg gcttatttgg cactttcaca attatattat aaaaattata
     1741 atcaataatt gcatctacaa actcaaaagg aataatcacc gtcttttcat catacttagc
     1801 ccaaaacaat aacttcattt gccaaataca agacaatttt aacttaaaga cttgactaaa
     1861 cttcacaaag agtgagatag ctttatactt aaaagaaaag ccttttttat acaggacctc
     1921 tccagagagg tataaattta tagaataaaa tagtctatgt ctataaactt ttcccataca
     1981 tgcttcataa tgacttgctt gctttttata taatttaatt cctaaattta ccccgtctct
     2041 agaacagata gcaatttctt tctttgtcaa agtgacgtaa aagcctaaag catataacaa
     2101 ttttgacact ttaagcaaat tagtagtaga tgtatctcct ccaataactg ctaaatcaat
     2161 atcattatcc caaggaataa acattttatc tctaacagct cctaaaagag taccagtatc
     2221 aataaaatat aataaattat ttttatcaag aacttcaata acttgtgata atactaacaa
     2281 ccatcgttgc tccttttcac ttattcctct agacatatcg cttcaacttt atatggattg
     2341 tttattaatc tttgaatatt aacagaagat acgattttcg atatgtcaat ttgagatatg
     2401 tcaatatcta atcccaagtt tcttatatac tctttcatag cgattgcaac atctacgcat
     2461 tccatattta accactgtaa cattttttgc attttaatct tatataagta aggatttata
     2521 ttaggattca ataagatatc cgaatttcca atattatatc tcataaaaaa gggaaatgtt
     2581 aatgctactg catgtccatg cggatatcca taatcagttg taaatgaata cgaaaaagca
     2641 tgtggagctg tagtcttagt tatattaatt gcacgaccag cccaataaga gccttccgaa
     2701 accttattcc tagcctccgc tgtaggagaa tttacaacca atggcaaatt aggccataag
     2761 agtttaattg ctttcgccgc atatttatcc gactcttccg tagcattcac attccaataa
     2821 gcttctatcg cctgcgctag agcatcaaag cctgtacaag atgttagata ttttgaattt
     2881 ccataagtaa attttggata tacaatcgct acatccggaa gaatagcatc atgttctact
     2941 gaatatttta ctttatcttt atataaaaca gaaaaatgag ttgcttcact acctgtacca
     3001 gctgtagtag gaagtgttat taatggaatt aattgtcgct tcttttcaaa ctcccccccc
     3061 gtaggattac cagaatagga ataaaaaaaa cgaagcaatt ttgccatatc taatacacta
     3121 cctccaccta tagcaataat catatttgtc ggatattctt tcaataatga aagtcctttt
     3181 tccatatctt caattttagg atttgcttca aaatcaaaga attccgtcac gccacaagct
     3241 aatttaacaa aaacagattc taacacagcc tgtgcaccac atttctcata agactttttt
     3301 cctcttacaa gaaatatatg atcaggagta tattcttgca agataggaat caattctttt
     3361 atagaagact ctcctaaaaa aaaacgctgt tccataatta ctctataaat tatctaagaa
     3421 aagcatgaat gcctctttat tttgtatagg agtgttggct ggtcttccca aattcttacg
     3481 agctcccttt cgaaccttta cttccaacaa aatagggccg cgtatttgct gtatcttttt
     3541 aagagcttca cataaacctt cgttatcaga aacagacaat actatttcat aaccacaagc
     3601 ttgagcaatt ttacataaat caatatctaa agcgactgtt ggttgtcccc ccacagaatc
     3661 gtgagcgcca ttattaaaga ctacgtgtac atagttttcc ggatgtaaag aaccgacaat
     3721 tgctaacgaa cccatatgca tcaaagtgga accatctcca tcaaagcaat aaactttaca
     3781 gtctctcttt ttaagagcta ttcccaatgc tatctgcgac gcgtgcccca tagaacctac
     3841 agtcaaaaaa tctctctcat gttctaaaga agtagattca cgatattcaa ataattcacg
     3901 tgatatcata cctgttgtcg atattataat atctttttct gttaatgaag ctgctatgaa
     3961 atgaatagca gcttcgcgtt tcaaagacaa ccgttcatct tcacaatttt cagaactata
     4021 ctctaagaaa gtgtctttct gaattacaaa agcaaaaggc tctcttgtct catccatgta
     4081 agattttgca acattaagtt gagatataaa cttcttttca tcttgagata aaacagcata
     4141 tctgataccc attgcctcaa gtaatggaag tgtgactttt ccctgcttaa tatgttgtgg
     4201 ctcatctttc acaccaggtt caccacgcca accaattagc aataacaatg gaatattata
     4261 aacttcttta tccgtcaatg acattaaagg atttactgca tttccaagac ctgaattctg
     4321 catataaaca actggaattt tcctcgtagc caaataatat cctgtagcca aacctatagc
     4381 agcaccttca ttagcggcaa taatgttatg ttcagaagca aggtgatctg ttaaatatgc
     4441 acatatattc ttcaataaag aatcgggaac tccagtaaaa aaatccatct gcatagcgcc
     4501 aagagagtct acaaaaatat taggagaaat cataataata agaatttaat tttaaagagt
     4561 ctatttactt agtccctgga atcaattcca gaatttcttt aataggcatg cataagtcat
     4621 tggcttcata agagcgtgca ttggcaagaa tggacttcgc cgtattaagc atagcgggat
     4681 atgcacttct aagcatatga tttgcatata ttacaacatt tactccccaa gaagccaatt
     4741 catcttctga tatatggtta taagtagttg gaacaaccac tatcggaatg gatttatgta
     4801 ttttgcgtaa agcaagacag aagttcttta tatcctcacc agacttatct ttgctatgga
     4861 tcataatccc atccgcacct gctttaatat atgctaatgc acgtcctaaa gcatcatcta
     4921 aaccttttcc agcaataaaa ctttcaatac gagctattat cataaaatca tccgttatct
     4981 gagcacgttt acccgcttga attttatcac aaaacccttc aattgtatcc tgggtctgaa
     5041 cagcgtctgt tccaaaaagc gagttcttct tcagacctat tttatcctcg ataataacag
     5101 ctgatatccc taaacgttcc agcgtgcgaa cagtaaatac aaaatgttct attttaccac
     5161 ctgtatcacc atcaaaaatt actggtttgg tagtacactc caaagcatca ttcaaatcat
     5221 gaagacgagt tgtcaagtca acggcttcaa tatcaggctt acctttagaa gtcgaatcag
     5281 taagactact ggaccacatc ccatcaaatt cacgcttaac tccgttgact tctacactgg
     5341 tattttctat tatcaaacct gttaacccac tatgagattc acagatacga acaatacttt
     5401 tagcagcaat taagcgttta agtcgcttca aacgaatttc gggagtggtt cctatttcct
     5461 tcaacctagt attcaataaa gtggaagaaa tacctttcgt ataaggaaca tctatcactt
     5521 ttccacccca tttagagata gtatcaatca cacgctggcg agtttcttgt tgaataccct
     5581 ctttccagtc atcaccatgt actacaaagt caggcctaat caattccaaa ttcggaacat
     5641 aatcaagagt agtttgaggt attacttcat caacaccctt caaattcaga actatcaatg
     5701 agcgctgatc aaaattcaag taaggcaaac gcttgtaact ggcaatagct gaatctgtta
     5761 atacaccaac cgttacatgc cccaattttg aagcctcatg aatgatattc aaatgacctg
     5821 gatgaataat atcagcactc atgccgacat aaaccttttt tttttccatt taattttaat
     5881 attacgaatt tatgagaata aacatattga aaaaatagca acaacaaaac ataaataatt
     5941 gaggaaggct tctgaaattc ccacgaaaaa atattgaaca ttgatatata gaccaaatat
     6001 atcataatac caagagtcag taatgttggt ttttgagtaa atttataaat actatatcgt
     6061 acgataaagc catataaaaa tgggaataaa agaacgccaa cgtaaccaaa atccaaataa
     6121 tgaaatatta tattagtgta tgcataatta aagatgattc cattcccaac tgaaattttt
     6181 gaattttgca aaagatgacc tatttcatca tgagcaatgg tataacttcc tcctaaataa
     6241 tggattacaa gttttaataa attatcaatt ccacccattg ttgcccttcc ataccaaaac
     6301 ccggttatcg attcataatt agctctaaat gaatagtcta aagctctaaa tggacctaaa
     6361 aaataccata cggcctgact ttttagttct tcaaaaccta tttttacgac ctcagcacta
     6421 aatgtatcaa atcccattct ttgagctgtc atatatgaaa taaccacaac tattattcca
     6481 acgccaacga acaagcatac aaaagaaact acaccaaaat tccatttttt ccttttgctg
     6541 gctaacaaat tgatatagta caattctctt cttaaataat aaatgataaa acaataaaat
     6601 agaaaaacaa tcaatccccc acgcccatta ccaacagatg cgtataaaaa cagaaaaagc
     6661 accgatagca acagaattct acgtttaatc ttagaaagta gcatacacgc tacaattagc
     6721 ataacaaact gtgtaaaagg ttttattaga aaatcatata gatatacttc taaattactc
     6781 gtaaaaagtt caccagcctc aaatctcatc atccgacctt cgcccgctcc atatagttca
     6841 ataactagag caaacttcat tgcgtaataa taagtaacaa tacatgccaa cataagaagt
     6901 aatatcatct tattattgcc aataaccaga ttataaaaac tattatctgt tgtaaccttc
     6961 aatcgtattt tttttatttt tccaaaacaa agaaatcccc aattaaacgc ccaaacattg
     7021 atcaataata acatatatgt tttcattgac acagaatata gttcagctgg atcaaaagta
     7081 gaaataacaa tagcagttcc ccaccacaat aaatatatga aacttatttt tcttgaaaaa
     7141 gaatcaatta taagcctatt agatatcaaa atctgaatta agaatagaat aagaaaaatt
     7201 atagcaatca tttgattcta tacttttgtc cctttgtcaa ccaccagaaa gaaacatata
     7261 aagccttata gatatctttc agattcttag gaaaataaga aaaagaatat ttcacaaata
     7321 aagtaaaatg atatatatat ttctttaagg aaatgtcaag tgattctgaa aatatagctc
     7381 tatgaacaaa tgccaaatat ctgtaataag gaaatttcaa atctttatta tgaaaatatt
     7441 caggaacttt taggtctaat acatgtaatg aataagaaac tctagaagta actcccattg
     7501 cattcttcct ataacaacac attacatctg gcatatataa aatatttcct ttcaacgaac
     7561 aagccaaaaa cagaaaacga tctccagcat ataaactact attgaaatct ttaatataat
     7621 caagtacttc ttttttaaaa aggaaagacg ctgtatgaaa aagtcttaca tccaataagt
     7681 ctttagtttt taaaatctgt tttttcacat gatgaaacat atgggatgga gttccattct
     7741 cataaaaaac taaagattga tgcgcacaac ctgctaacga atgatcactc tccattgcat
     7801 ttacttgttt ttgtaacttc aacggatcag tccaataatc atccccctca caaagcgcaa
     7861 catatttacc ttttactaaa ggaaataata tttgacgtaa cggagaaata ccttgagaat
     7921 actggtttcg aatctgaaga attggtttaa taagattagg atatgccaca acatattcat
     7981 taataatact ctgagtagca tcagaagacg catcatcatg aacaagaatt tcaaaatcaa
     8041 attctgtttt ttgcattata aggccatcta aacactgcct tatatatttt tcatgattat
     8101 acgtcaagca acatatgcta actgttattg aaccgttcat ttattttaat cttaattcag
     8161 caaaacgctt tatttccatt tcacttttat aatcctcaaa caacttacga caatcatatt
     8221 gaggcacata tcctaattct ttctttgcat tttcaatgtt cattatgtac ccaccaccac
     8281 aaactttgtc tggtctatat ataacttcag atggtgactc cttaggcgaa aaaacactaa
     8341 taatagtgcg aatttgttct tctaatgtaa ttggcattcc tgtacccaca ttataaaagc
     8401 cactttcttg ttccacctca acagctttac acaacatttg actaaaatcg ttaacatgaa
     8461 ccatatcctt tgcataatga ggatctcccc atatctctat aggtagtcct ttctgagcat
     8521 tttcaatcat ttggtaaata ggtcgcttcg tcttgactcc attaggaaag tagtacggat
     8581 aagggctata gctatatatt gttggaagcc taaaaatgaa ttttttcaaa ccgtattctt
     8641 gataataatg ctctatcaag tctaaagcag tatttttgga aattacatat atagcatgat
     8701 cacccgtata gctaaaattt ggtttcatat cgggttttaa aatagtatca tgagaataca
     8761 atgaaatatc aaaaacggtt tgagtataaa ttatcctatc tacatgacat ttgcggcaat
     8821 actctaatac attaaatcct cctattacaa tagaatctaa atactttatg gggcaataag
     8881 tatccatata agaaggtatt tgagcagaga gtagcataac tgcatgtata ttttccattg
     8941 gaagcttatc aaaatcttct tccttcgtaa tgtccacaga ataatatggt attccccttt
     9001 tggaaaaaaa agtagtttcg cgacgtcctg aagctattat ttcatactct tccttattaa
     9061 agaaatttaa tgcgtattct aacaaataag accctgtatt accggttgct ccaaaaataa
     9121 taattttctt tttcatgata aatggttatt taagttagat attttttcaa ttaatatatt
     9181 cattgttttt tcatcatatc tctgatctat aggcaatgca atcatattat tcgcgattga
     9241 gtattccaga catttagcgt ctatcttatt cactacgttt tgccaatatt gaggtacata
     9301 tacgtgctct aatattaatt gttggcgaag cccagctttg ctcgtataaa aaggatatat
     9361 caacgggaca ttttgatttt cagaaatact aaaatcaaat ttattaaatg cagttaatgc
     9421 actgtagaga agatgataat taaaacgacg cctttcaatt attgagacgt aatccaaaga
     9481 agacaaaatt ttatcagaca atacagacat tctatgtatc tcttgatttg acatcctttc
     9541 ttcagattct tgaaaatctt tataataccc ctctgcagag tcagttatac gccctatcaa
     9601 gtagttaata ttatcaatag gattataaat cgggaaatca atatccagta acgcagttgt
     9661 gtacaaataa gcgccatctg gaactccaaa aaatttacgg gcagaataaa atgtatctac
     9721 cccttcaatt ggttttgcaa aaaaagcttg tgcattatca actattaagt taggataaaa
     9781 ccgagataaa taaagaacag tatcttgttt taagccgaaa taattagtat atagaaaagc
     9841 ctctgagctt tctatttttt tatcaaacac aggatccagt aaactattta tatgataata
     9901 ttcatacttt acatttaatt tcatgagagg ttctattatc acatcacaag tgtaatatgg
     9961 aatatacact tttgtatacc gtctagcttt taatatatac tcaaagcatt gacgagcagt
    10021 actcagtttt attgcacctt gatgaaaatg ttctccttca cgtatttcca gttcaaaata
    10081 gccacctatt gacatcattg taaactaaat gaatctaata acatacaagt ttcttcttta
    10141 gaattattca ttagtacatc tattattgat aaatatggaa caaattcttt agattgctgg
    10201 ggataccttt ttattatcgt atctacaaat ttcaaattaa taccattttg cataaagtct
    10261 tccttattat agatttgttt tccacctata gcattataat aagtatctgc cgatagtaac
    10321 ttacaaatat gaagaacttt atcctttcct tttaaagagc aatctttagg taaatctgaa
    10381 gatagcaata tttcagtctg aatatttaga taatctaaaa tttctttaaa actattagcc
    10441 aagaagagag ccaattgtct atttggaaac ataattatcc tatacaacaa ttccattgtt
    10501 tcatgataga aaggagcttt agagtaattc aattccaatg ttttcataaa tttacgaaaa
    10561 tcatctccta tctctatttc attgaaatgt ttataggcac tagccccctt caaagtgata
    10621 gtaaacattt tcttttcacc atttaccaat atattgttac gattcaccca ccctccttta
    10681 atataattaa catcatcgta tacaacgtat ttatcaacag ccttaattag ctggaaataa
    10741 cctatataag gcataaaata aggttgcatt atacctaatt tcatttcaat atcagattta
    10801 aaattctttc aacatcttca ttcgacaatc cacaatacat tggcaagcag attacacttt
    10861 ttgccattt
//
