LOCUS       gnlProkkaINANKBAO_402  12551 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|INANKBAO_402.
ACCESSION   gnlProkkaINANKBAO_402
VERSION     gnlProkkaINANKBAO_402
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-18 10:35:54
            Original ID  :: gnl|Prokka|INANKBAO_402
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12551
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12551
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[2203:2551]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2204..2551
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..12551
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12551
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             771..2159
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 90.5; E-value: 1.4e-27)"
                     /gene_kind="transport"
                     /locus_tag="ctg402_1"
                     /transl_table=11
                     /translation="MTEQLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AITTTFPEGAMLFGFKMQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGSTDESGVFHTNIPAPILFCLVMLCVGTIAFFIYTF
                     YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMVIGSVMLIFVHTMFAL
                     PILNIWWFATVIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNSYCKGPVVDGAQTYDYTLPMAIFAMFGVLALIVALMLKVENKKKGYGLEEA
                     NIQK"
     CDS             2204..2551
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg402_2"
                     /sec_met_domain="PF05402 (E-value: 1.9e-17, bitscore: 53.8,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PqqD_RRE (E-value: 7.2e-10, bitscore:
                     29.0, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATKEKINLLEVIPCRNEHIKAEQEGETIVLSFPRFKRSWMSRYL
                     LPKGMSKDIHVRLEEHGTAVWNLIDGQRTVREIIEKLADHFQYEAGYESRVSTYLSQLQ
                     KDGFIKWIIIH"
     CDS             complement(2541..2828)
                     /locus_tag="ctg402_3"
                     /transl_table=11
                     /translation="MGGEGHMLDMIRRLKDGKEASRLRRERRNDKLGRLRRNNDPYLLP
                     DTTPEEMERIIKDSEKKKEKDNSYFVWGTLIIMGVLIGCAVLLWAIFFNG"
     CDS             complement(2850..3914)
                     /locus_tag="ctg402_4"
                     /transl_table=11
                     /translation="MKKFIIATGLLVATSAYAQTEVLTGVTRGKDYGVVYALPKTQIEI
                     EIKANKVNYKPGEFSKYADRYLRLTNVSAEPEEYWELNSVKVKPVGVPNSEATYFVKLK
                     DKTVAPLMELTEEGLIKSINVPYSSNNAKNAANNAVAPQRKANPRDFLTEEILMASSTA
                     KMAELVAKEIYNIRESKNALLRGQADNMPSDGAQLKIMLDNLNLQEEAMTEMFSGVRNK
                     EEKTFTVRLTPDKEFDNEVAFRFSKKLGIVANNDLAGTPFYISLKDLKTVKIPQEDGKK
                     KKEMEGIAYNVPGQAMVTLSDGKKKLYEGEIPVTQFGIIEYLAPVLFNKNSTIKVYFDP
                     VTGGLLKVDREESK"
     CDS             complement(3988..5499)
                     /locus_tag="ctg402_5"
                     /transl_table=11
                     /translation="MKIFPSSSIKKLDAYTIEHEPIASIDLMERAAQALTKAITNRWNP
                     ETPVTIFAGPGNNGGDALAIARMMAEKGYKIEVYLFNTKGELSPDCQTNKELVEMMEEV
                     TFHEISTQFVPPTLTPEHLVIDGLFGSGLNKPLSGGFAAVVKYINASPAMVVSIDIPSG
                     LMGEENTFNVKSNIIRADVTFSLQLPKLAFLFAENTEFVGEWELLDIQLSEEGIEETET
                     NYEMLEIEEIRSLIKPRQQFAHKGNFGHALLIAGSKGMAGASVLAARACLRSGVGLLTV
                     HAPLCNNDILQTSAPEAMVETDVSETCFAVPTDTDDYQAVGIGPGLGRNEETEAALIEQ
                     LEHCQTPTVLDADALNILANHRHTLTHLPKGSILTPHPKELERLVGKCQDSYERLMKAC
                     ELAHTAKVHIILKGAYSAIITPEGKCYFNQTGNPGMATGGSGDVLTGVILALLAQGYPA
                     EDAAKIGTYIHGLAGDIAQKKQGMIGLIASDIVTCLPTAWRLVSE"
     CDS             complement(5965..6468)
                     /locus_tag="ctg402_6"
                     /transl_table=11
                     /translation="MYILSVVVKYRTLTHKAFTAKVIVKGDELTSEEHTELMNKVGNSY
                     PINKYVFTFMNAEDSKGTVDLYYSDNNMKTGNFEKEHIVLDEENAIPIKGEYKLSEYYR
                     ITIKEDNGKVIDTFYITKNFLPLLNTRMNAHPLIQYCFVRDLTAQYKQDYLALENAYLI
                     QIAE"
     CDS             7071..7295
                     /locus_tag="ctg402_7"
                     /transl_table=11
                     /translation="MMEKKRIGSNAGKVWRILNEKGEQSMFTLCHELGLTFEDVAIAIG
                     WLARENKILLRKKEGMLYASIENVEFTFG"
     CDS             7488..9032
                     /gene_functions="transport (smcogs) SMCOG1202:major
                     facilitator transporter (Score: 56.1; E-value: 3.9e-17)"
                     /gene_kind="transport"
                     /locus_tag="ctg402_8"
                     /transl_table=11
                     /translation="MSSLKGHPKGLYLIFATSTAERFSYYGMRAIFILFLTQALLFDKE
                     AAASIYGSYTGLVYLTPLIGGYIADKYWGIRRSVFWGAVMMAVGQFLMFMSASSLNNTD
                     LAHWLMYGGLGFMILGNGCFKPTVSSLVGQLYEPGDKRLDAAYTIFYMGVNVGSFAAPL
                     ICGFLGDTGNPQDFKWGFLASGIMTLFTVVLFETQKNKYLFSPSGEPIGIVPDARREKK
                     EDKAEHISHPKMDKRTKVRNIIIITALTVALIAFFSYAFSDDWISVGIFTACIVFPVLI
                     LLDGSLTKVERSRIFVIYIVAFFVIFFWAAYEQAGASLTLFASEQTDRSIFGWEMPASW
                     FQSFNPLFVVILAYIMPGIWSFLNKRNMEPASPTKQAIGLLLLSLGYLFICFGVKDAIP
                     GVKVSMIWLTGLYFIHTMGEIALSPIGLSMVNKLSPLRFASLMMGIWYLSTATANKFAG
                     MLSGLYPEDGKVKSILGYQIATMYDFFMLFVIMSGVASLILFLLSKKLQKMMHGVE"
     CDS             9074..9610
                     /locus_tag="ctg402_9"
                     /transl_table=11
                     /translation="MDTIQIKDKQFTVSIKEQDIQKEVIRVANEINRDLAGKNPLFLSV
                     LNGSFMFTADLLKHITIPCEISFVKLASYQGVTSTGVIKEVIGLNEDIAGRTVVIVEDI
                     VDTGLTMQRLLDTLGTRNPEAIHIASLLVKPEKLKVNLNIEYVAMEIPNDFIVGYGLDY
                     DGFGRNYPDIYTVVD"
     CDS             9644..10213
                     /locus_tag="ctg402_10"
                     /transl_table=11
                     /translation="MLNIVIFGAPGSGKGTQSERIVEKYGINHISTGDVLRAEIKNGTE
                     LGKTAKGYIDQGQLIPDELMIDILASVFDSFKDSKGVIFDGFPRTIAQAEALKKMLAER
                     GQDVSVMLDLEVPEDELMVRLIKRGKDSGRADDNEETIKKRLHVYHSQTSPLIDWYKNE
                     KKYQHINGLGTMDGIFADICEAVDKL"
     CDS             10226..11392
                     /locus_tag="ctg402_11"
                     /transl_table=11
                     /translation="MAESNFVDYVKIYCRSGKGGRGSTHMRREKYCPNGGPDGGDGGRG
                     GHIILRGNRNYWTLLHLKYDRHAMAGHGESGSKNRSFGKDGADKVIEVPCGTVVYNAET
                     GEYLCDVTDDGQEVILLKGGRGGQGNSHFKTATRQAPRFAQPGEPMQEMTVIMELKLLA
                     DVGLVGFPNAGKSTLLSAISAAKPKIADYPFTTLEPNLGIVSYRDGKSFVMADIPGIIE
                     GASQGKGLGLRFLRHIERNSLLLFMVPADSDDIRKEYEVLLNELRTFNPEMLDKQRVLA
                     ITKSDMLDQELMDEIEPTLPEGVPHIFISSVSGLGISVLKDILWEELNKESNKIEDIVH
                     RPKDVTRLQQELKDMGEDEELDYEYEEDADDDDDDLDYEYEEEDWEEK"
     CDS             11416..12201
                     /locus_tag="ctg402_12"
                     /transl_table=11
                     /translation="MLGYESLSSYSNISHFVTTRQGGCSEGNYASFNCTPYSGDEAEKV
                     RRNQTLLMEGMSQTPEELVIPVQTHETNCLLIGDAYLSASSQQRQEMLHGVDALITREP
                     GYCLCISTADCVPVLIYDKKHSAIAAIHAGWRGTVAYIVRDTLLRMEKEFGTSGEDVVA
                     CIGPSISLASFEVGEEVYEAFQKNGFDMPRISIRKEETGKHHIDLWEANRMQILAFGVP
                     SGQVELARICTYIHHDEFFSARRLGIKSGRILSGIMIHK"
ORIGIN
        1 tatccaaaaa aaaatgctta ctttgcagac caaatcagat ttttggagaa attgattatt
       61 aacgctaatt caaaataact aaaaatgtac ttattattca ttatcttaat ggtgattgca
      121 gccttgctga tgtgcttcat cgtgctgatt cagaattcaa aaggaggcgg acttgcttct
      181 ggtttttctt catcaaacgc tatcatgggc gtgcgcaaga ctacagattt tctggaaaaa
      241 gcaacttggg gtctggctat cttcatggtt gtgatgagcg ttgctactgc ttacgttgtt
      301 ccttcttctt ctgcagctaa agatgtattg ttggaacaag cacagaaaga acaacaaacc
      361 aacccgtata atatgcctac cggtactgct gctcctcaga cagatgctac tgctcctgca
      421 gagtctgcac cagcaacgga agctccggct actgaaactc ctgctcctgc agcagaataa
      481 ttcagtgaca ggatattcgg tttaaactta ttgagtgaac gggctttttg acccgttctc
      541 ttcattatag gcgcgaatta cgcgaattac aagagattct aatagaatcg tgtaatacgt
      601 gtagttcgcg cctgtcttta ttattgggcc cggtctgctc ttcttcatac aggaatatcc
      661 ggtcagatgt cctttttctt ataaaatgtt ctcctttttt agtaaaacaa atgataatta
      721 gttaactttg ttgcccgtta cgagattatt aactcctttt aaatattaca atgacagaac
      781 aattgaaaca aaagctgaat gactccgcag tgctgcgttg gagtgttcta gcattagtcg
      841 cttttaccat gttgtgcggc tacttcctca cagacgttat gtctcctctg aaacccatgc
      901 ttgaaaaaga acttctctgg gacagtttag attacggttt tttcaccagt gcttatggct
      961 ggtttaatgt attcctgctg atgctcatct ttggtggtat cattctggat aagatgggag
     1021 tacgcttcac cggaatgggt gcctgtttat tgatggtgtt cggttgtgga ttgaaatatt
     1081 atgctattac tactactttc ccggaaggtg cgatgctttt cggattcaag atgcaagtca
     1141 cattggctgc attgggttat gctattttcg gtgtaggagt cgaaattgcg ggtatcaccg
     1201 tttcgaagat tatcgtgaag tggtttaaag gcaaagagat ggctctcgct atgggactgg
     1261 aaatggcgac cgcgcgtatt ggaacgactt tggccatggt gcttaccgtt cctttggcag
     1321 acttcttcgg gtctacggat gagagcggcg tattccatac caatattccc gctcctattc
     1381 tgttctgtct cgtcatgttg tgcgtaggta ccatcgcatt cttcatctat actttctacg
     1441 ataagaaact ggatgcttca ctggatgcgg aaggactgga accggaagaa cctttccgca
     1501 tgaaagacat tgtctatatc attaccaaca aaggattctg gctgatcgca ttactgtgcg
     1561 tattgttcta ttcggctgta ttccccttca tcaagtatgc ggccgatttg atggtacaga
     1621 agtacaatgt tgatccgaaa cttgcgggaa cgattcccgg attgctgccg attggcgcga
     1681 tcatcctgac accgttgttc ggttcattat atgaccgtat cggtaaggga gccacgctga
     1741 tggtgatcgg gtcggtgatg ctgattttcg tacacacgat gttcgctctt cctattctga
     1801 atatatggtg gtttgcaacg gtgatcatga ttattctggg atttgctttc tcattggttc
     1861 cttcggcaat gtggccttcg gttccgaaga ttattccgga gaaacagttg ggaacggctt
     1921 atgcgctgat cttttgggta cagaactggg gattgatggg cgtgcctttg ctgatcggat
     1981 gggtgttgaa ttcttattgc aaaggtccgg ttgtagatgg tgcacagact tatgattata
     2041 ctttgccgat ggctattttt gctatgttcg gtgtacttgc cctgattgtt gccttgatgc
     2101 tgaaagtgga aaacaagaag aaaggctacg gactggaaga agcaaatatt cagaaataat
     2161 cacagtatat attctatctg aaaagatata aaagagaaaa gatatggcta cgaaagagaa
     2221 aataaacctc ctggaggtga tcccttgtcg taacgaacat attaaagctg aacaggaagg
     2281 ggagactatt gtgctctcct tccctcgttt taaacgttcg tggatgagtc gttatttatt
     2341 gccgaaagga atgtccaaag atattcatgt gcgtctggaa gaacacggta cggccgtatg
     2401 gaacctgata gacgggcagc ggacggttcg tgagattata gaaaaactcg cagaccactt
     2461 tcaatatgaa gcaggctacg agtctcgtgt atctacctat ctttcccaat tacagaaaga
     2521 cggatttatt aaatggataa ttatccatta aaaaagattg cccacaggag gacagcacat
     2581 cctatcagta cgcccataat gataagcgtt ccccatacga aatagctgtt atctttttct
     2641 tttttctttt ccgaatcctt gatgatgcgt tccatctctt ccggagtcgt atccggcaga
     2701 agataagggt cgttgtttct tctaagtcgc cctaacttgt catttctccg ttcacggcgt
     2761 aagcgggagg cttctttgcc gtctttcagc cgacgtatca tgtcgagcat atgtccttcg
     2821 ccacccatcg ttttgttttt ttagaggttt tatttgcttt cttctctatc tactttcagt
     2881 agtccaccgg tcaccggatc aaagtaaact ttgatggtcg agttcttgtt gaataatacc
     2941 ggagcaaggt attctatgat accgaactga gtaacaggta tttctccttc atacaatttc
     3001 tttttgccgt ccgacagcgt caccattgcc tgtcccggta cgttataagc aatgccttcc
     3061 atctctttct tcttttttcc gtcctcttgc ggaatcttca ccgttttcag gtctttcaga
     3121 ctgatgtaga atggagtgcc tgccaaatcg ttgttggcaa ctatacccag cttctttgaa
     3181 aagcggaaag ctacctcatt gtcgaattcc ttatccggag tgaggcggac agtaaatgtc
     3241 ttttcttctt tattgcggac tcccgaaaac atctcggtca tggcttcttc ctgaagattc
     3301 aggttgtcga gcatgatttt gagctgtgcg ccgtccgaag gcatattatc tgcttgtccg
     3361 cgcaataatg cgtttttact ttcgcggata ttatagattt cctttgctac cagttcggcc
     3421 atcttggcgg ttgaacttgc catcagaatt tcttctgtga gaaagtcgcg gggattggct
     3481 tttcgttggg gagcaacggc attgtttgct gcattctttg cattgttgct gctgtagggg
     3541 acgttgattg atttgataag accctcttca gtcagttcca taagaggagc tacggttttg
     3601 tctttcagtt tgacgaaata agtagcttcg ctgtttggta cacctacagg tttcactttg
     3661 acactgttca gttcccagta ttcttcgggt tcggcagaga cgttggtcag tctcaggtag
     3721 cggtcggcgt atttgctgaa ttcacccggc ttatagttga ccttgtttgc ttttatttct
     3781 atttctatct gggttttggg gagggcgtac actactccgt agtcttttcc tcgcgtcact
     3841 cctgtcagca cttcggtctg cgcataggcg gaagttgcca ctagtagtcc tgttgctatg
     3901 ataaactttt tcatattcgg ttctttttag ctgattttga aaaacaaagt taatgaagtt
     3961 attgaataaa ccgtaagttc ttaactttta ttcgcttaca agtcgccatg ccgtcggcag
     4021 acaggtcacg atatcacttg cgattaatcc gatcatgccc tgttttttct gggcgatgtc
     4081 tccggccaat ccgtgaatgt aagtaccgat ctttgcggcg tcttcggcgg gatagccttg
     4141 cgcaaggagt gcaaggatta ctcctgtcag tacatctccg ctgcctcctg ttgccatacc
     4201 gggattaccg gtctggttga agtaacattt gccttcgggg gtgataatgg cggaataagc
     4261 tcccttcaga atgatatgta ctttggcagt gtgcgccagt tcgcaggctt tcatcagtcg
     4321 ttcgtatgag tcctgacatt tgccgaccag gcgttccagc tctttcgggt gaggggtgag
     4381 gatggaacct ttcggcagat gggtgagcgt atgccggtga ttggccagaa tattgagtgc
     4441 gtcggcatcc agtaccgtcg gagtctgaca atgttccagt tgttctatca gggcggcttc
     4501 cgtttcctcg ttgcgaccga gtcccggacc gatgccgaca gcttggtaat cgtccgtatc
     4561 ggtaggtacg gcaaagcatg tttcgctgac atctgtttct accatggctt cgggggcgga
     4621 cgtttgcaga atatcgttgt tgcataacgg cgcgtgtacg gtcagcagac ctactcccga
     4681 gcgcagacag gcacgcgcgg ccagtaccga tgcacctgcc attccttttg agccggctat
     4741 cagcagggca tgtccgaagt ttcctttatg ggcgaattgt tggcgtggtt tgatcagtga
     4801 acggatttct tcgatttcca gcatttcgta gtttgtttca gtctcttcga ttccttcttc
     4861 gctcagctgg atgtccaata actcccattc gccaacaaat tctgtatttt cggcaaagag
     4921 gaaggccagt ttaggaagtt gcaggctgaa agtgacgtcc gcacggataa tattgctttt
     4981 tacattgaat gtattttctt ctcccatcag tccggaaggg atgtcgatgg agactaccat
     5041 ggcgggagag gcattgatat atttcacaac ggcagcgaat cctccgctca atggtttgtt
     5101 gagtccggaa ccgaataatc cgtcgatcac gagatgttcc ggtgtcagtg tgggaggtac
     5161 gaactgggtg ctgatttcat ggaaagttac ttcttccatc atctctacca gttctttgtt
     5221 ggtctgacag tcgggcgaaa gttcgccttt cgtgttgaag agatatactt cgatcttgta
     5281 tcctttttcc gccatcatgc gggcgatggc gagggcgtct ccgccattat tgcccggtcc
     5341 ggcaaagatg gtgacaggtg tttccggatt ccatctgttg gtgatggctt tagtcagcgc
     5401 ctgtgcggca cgttccatta aatctatgga tgcaatcggt tcatgttcaa tggtataggc
     5461 atctaacttc ttaatgctgc tgcttggaaa tattttcatt gcgatattct tttagttttc
     5521 gacgcacaaa cttacacaaa aactctgaat taatccttta ttccggttgg ttttcggctt
     5581 tttgggaagg aacttcaggt attaatactt gagttgtcag gtattaatag ttgatgtgtc
     5641 agttattaat agttgagaag tcagatatta atgattgtta tctcatttac ttttactctc
     5701 tccggagaac attcatggct gtttgttaac cttcccatgc gtgtttctac tactgtatat
     5761 tcctctggtt cacctctttc acccgcaatc gccttattca tcaaaggttc aggaaaaggg
     5821 tggaagaggt gattgtgata aatatgctat gggcatattc ttgattagct aatagcttat
     5881 tgttttttgc taaatctaat ggggagtttg ctcatataat aaatactcta ttcactctgc
     5941 taaagaagaa aatcagtgta gctctcattc tgctatttga atcagatatg cattttccag
     6001 tgcaaggtaa tcttgtttgt actgtgcggt taaatctctg acaaaacagt actgaattaa
     6061 cggatgagca ttcattcttg tattgaggag tggtagaaag ttcttggtaa tatagaaagt
     6121 atcaataact ttgccattat cttctttgat tgttatacgg taatactcac tcaatttgta
     6181 ttcacctttg atgggaatgg cattttcttc atccagcact atatgttctt tttcaaagtt
     6241 gcctgttttc atgttattat ctgaataata caaatctact gttcctttgc tgtcttccgc
     6301 attcataaaa gtaaatacat atttattaat cggatatgaa ttgcccactt tgttcattaa
     6361 ctcagtgtgt tcttcagatg taagctcgtc tcccttcaca atgacttttg ctgtaaacgc
     6421 cttatgagta agagtacgat attttacaac gacagacagt atatacatat tatttgaact
     6481 gtcttctatc ttgatggatg cgcgtcctat ttcctttgcc ttcaatgtta aacttccgtt
     6541 gtggtagttt acttgtacca ctttctcatt ctcattggtc actttgtaag ttccgtctcc
     6601 acccttgatg aagagtggtg tcgtttcttt gctgaacgga gtcagtgtgt aagaacggct
     6661 ctcgttgtcg aacttaattt gaggatcttc atattccaga gtgattggag aaaagttgtc
     6721 atcattgtca ttacagctca cgaggcaaat aatacaaagg aataacgaaa gtattcctgt
     6781 tagttttttg gtagtcatgc taattaaagt tttaaatgtg cgatattagt ttagttctcg
     6841 tctgcaaact tatgaaaaag aattgaactg tttctttatt tgtgctattt tttagcagag
     6901 atcggcataa atgattagaa tgtaactaat aatagcagct aatgctttga ttatttgctt
     6961 ttttcgaaaa aaatgatatc tttgtagtgc agtaatgtgc tttacgttat tctcctgtgc
     7021 tcacaatgtt tagattataa atataaattg tttaatcttc taaagtttgc atgatggaaa
     7081 agaaaagaat tggctcaaat gccgggaaag tatggcgcat cttaaatgaa aagggcgaac
     7141 agtctatgtt cactttgtgc catgagttag gtttgacgtt cgaggatgta gcgattgcta
     7201 tcggttggct ggcaagggaa aacaaaatcc tgcttagaaa aaaagaagga atgctctatg
     7261 ccagtattga gaatgttgaa tttacctttg gataaatggg gactgaccca catttaagga
     7321 gaatatccac ttgattattt acactgttga aaacataata aggtgggtaa ctgagacttc
     7381 ttgcacgcca tcctgtattt ttctattcca taagaatctt cttttttgag gcatttaatc
     7441 tactttttag tacctttgcg ccccataaac tactaaacac ataattcatg agttcattga
     7501 aagggcatcc gaaaggcctt tacctaattt tcgcaacgag cacggcagaa cgtttcagtt
     7561 actacggtat gcgtgctatc tttatcctct ttctgacgca ggcattgctt tttgataaag
     7621 aagcggcggc ctctatctac ggtagctaca ccggactggt ctatctgact ccgttgatcg
     7681 gcggatacat tgccgataaa tattggggca tccgtcgttc ggtattttgg ggagcggtga
     7741 tgatggcagt cggtcagttc ctgatgttta tgagtgcctc ttcactgaac aatacagacc
     7801 ttgcccactg gctgatgtat ggcgggctcg gattcatgat tttaggtaac ggttgcttta
     7861 agcctaccgt ttcttcgctc gtcgggcaat tatatgaacc cggggacaaa cggttggatg
     7921 ctgcatacac cattttctat atgggtgtta atgtaggttc ttttgctgct cctttgattt
     7981 gcggtttctt gggagacaca gggaatccgc aggactttaa atggggattc ctcgcatccg
     8041 gaatcatgac gctgttcact gttgtcctct ttgaaactca gaagaataaa taccttttct
     8101 ctccttccgg tgaaccgatt ggtatcgtcc ccgacgccag acgtgaaaaa aaggaggata
     8161 aagccgaaca tatttcacat ccgaagatgg acaaacgtac caaagtacgt aatatcatca
     8221 tcattactgc ccttacagtt gccttaatag ctttttttag ctatgccttt agcgatgact
     8281 ggattagtgt gggtatcttt acggcttgta ttgtctttcc agtgctcatt ctgctggatg
     8341 gttcattgac caaagtagaa cgtagccgta ttttcgtaat ctatatcgta gctttcttcg
     8401 tcattttctt ctgggcagct tacgagcagg caggagcttc tctgacatta ttcgcttccg
     8461 aacagactga ccgcagcatt ttcggctggg agatgccggc ttcgtggttc cagtcattca
     8521 atccgctttt tgtagtgatc cttgcctata ttatgcccgg tatatggagc tttctgaata
     8581 agcgaaacat ggaaccggct tcccctacca aacaggcaat cggtctgtta ctgctttctc
     8641 ttggttatct cttcatctgt tttggagtga aagatgctat tccgggagta aaggtgagca
     8701 tgatctggct gacaggactt tattttattc atacaatggg agaaatcgct ctgtcaccta
     8761 tcgggctttc tatggttaat aagttgagtc cgttacgttt cgcctccttg atgatgggga
     8821 tctggtatct ttctaccgcc accgcaaata aatttgcagg tatgctgagc ggcctctatc
     8881 ccgaagacgg aaaagtgaaa tcaatccttg gttatcagat tgctaccatg tatgacttct
     8941 tcatgctgtt cgtcattatg tccggtgttg cttcactgat tctgttcctt ctctcgaaga
     9001 aattacagaa gatgatgcac ggggtagaat aaaaaattgt atttttgcga caactttttt
     9061 aaaatgaccg gttatggata ccatacagat aaaagacaag caatttactg tttccattaa
     9121 ggaacaggat attcaaaaag aagtgattcg cgtagcgaac gaaatcaatc gtgatttggc
     9181 aggtaagaat ccgctcttcc tcagtgtgtt gaacggctcg ttcatgttta ccgccgactt
     9241 gctgaagcat atcacgattc cgtgcgaaat ttcatttgtg aagttggcat cttatcaggg
     9301 ggtgacttcc accggagtaa ttaaagaagt gatcgggctg aatgaagaca ttgccggacg
     9361 tacggtagtg atcgtagaag atattgtaga taccggactg acgatgcagc gtctgctgga
     9421 tacactgggc acacgcaacc ccgaagcgat tcatatcgcc tctttgctgg tgaaaccgga
     9481 aaagctgaag gtcaatctga acatagaata cgtagcgatg gaaatcccga atgattttat
     9541 cgttggctac ggattggatt atgatggttt cggacgcaat tatcccgata tttatactgt
     9601 agtagattaa attcaaatac aaattaattt ataggttaaa aagatgttga acattgtaat
     9661 tttcggtgct ccgggttcag gaaaaggaac gcagagcgaa cgtattgtag aaaagtatgg
     9721 aatcaaccac atttcgacag gagatgtatt gcgtgcagaa atcaagaacg gcacggaact
     9781 gggcaaaact gctaaaggtt acatcgacca gggtcagttg attccggatg aattgatgat
     9841 tgatattctg gcaagcgtat tcgatagctt caaagacagc aaaggtgtaa ttttcgacgg
     9901 tttcccaaga acaattgcac aggcggaagc attaaagaag atgttggcgg aaagaggaca
     9961 ggatgtttct gtaatgttgg atctcgaagt tccggaagat gaactgatgg tacgtctgat
    10021 caaacgtggc aaagactccg gtcgtgccga cgacaacgaa gaaacaatca aaaaacgtct
    10081 gcatgtatat cattcacaga catctccgct gatcgactgg tacaagaacg aaaagaaata
    10141 ccagcacatc aacggtctgg gtactatgga tggtatcttc gctgatatct gcgaagcagt
    10201 agacaaatta taataaataa aaaatatggc tgaatcgaat tttgttgatt acgtaaagat
    10261 atactgtcgc tcaggcaagg gcggaagagg ctctacgcac atgaggcgcg agaaatattg
    10321 tcctaacgga ggtcccgatg ggggcgatgg tggaagagga ggccatatta tcttgcgcgg
    10381 taaccgtaat tactggacat tgcttcactt gaagtatgac cgtcatgcga tggcaggtca
    10441 tggcgaatcg ggcagcaaga accgtagttt cggaaaagac ggtgcggata aagtgatcga
    10501 ggtaccctgt ggaacggtag tgtataatgc cgaaaccgga gaataccttt gcgatgtgac
    10561 ggacgacgga caggaagtga tcttgctgaa aggcggtcgt ggcggtcagg gtaacagtca
    10621 tttcaagacg gctacccgtc aggctccgcg ctttgcgcag ccgggcgaac cgatgcagga
    10681 aatgacggtg atcatggagc tgaaactgtt ggcagatgta ggactggtag gtttcccgaa
    10741 tgcgggaaag tctacgttgc tttctgccat ttcggctgcg aaaccgaaga ttgccgatta
    10801 cccgtttacg acactcgaac cgaatctggg aattgtttcc tatcgcgatg gaaagtcatt
    10861 cgtgatggcg gacataccgg gcatcatcga gggagccagt cagggaaaag gattgggact
    10921 gcggtttctg cgtcatatcg agcgtaactc gttgctgttg ttcatggttc cggcagatag
    10981 cgatgatatc cgcaaggagt atgaagtatt gctgaatgag ctgcgtacgt tcaatcccga
    11041 aatgctggac aaacaacgtg tgctggctat cacgaagagc gatatgctcg atcaggagct
    11101 gatggacgag attgaaccga cattgcccga gggtgttccg catatattca tttcttctgt
    11161 ttccggtttg ggaatctcag tgttgaaaga cattctgtgg gaggaactga acaaggaaag
    11221 taataagata gaagacattg ttcaccgtcc gaaagacgtg acccgtctgc agcaggaact
    11281 caaggacatg ggcgaggatg aagaactcga ctatgaatat gaggaagacg ctgacgacga
    11341 cgatgatgat ctcgactacg aatacgaaga agaggattgg gaggaaaaat gatttcaatc
    11401 acaagagata aaagaatgtt ggggtatgag tcgttaagct catactccaa catttctcat
    11461 tttgtaacta cccggcaggg agggtgcagc gaaggaaatt atgcgtcatt caactgtacg
    11521 ccctacagtg gagacgaggc ggaaaaggtc cggcggaatc aaacgcttct gatggaagga
    11581 atgtcgcaga cacccgaaga actggtgatt cctgtgcaga ctcatgagac gaattgcctg
    11641 ctgatcgggg atgcttattt atcggcttcg tctcaacaac gacaggagat gctgcacgga
    11701 gtggatgctt tgattacccg cgagccggga tattgtcttt gtatttctac tgcggattgt
    11761 gttcctgtgt tgatatatga taagaaacat agtgccatag ctgccattca tgccggatgg
    11821 agagggacgg tagcatacat cgtgcgtgat actttgttgc ggatggaaaa ggagtttggc
    11881 acaagtggag aagatgtagt tgcctgtatc ggtccgagta tctcattggc ttcttttgaa
    11941 gtgggtgagg aagtgtacga agcatttcag aagaatggtt ttgatatgcc tcgtatttct
    12001 atcaggaaag aggaaaccgg aaaacatcat atcgacttgt gggaagcgaa ccggatgcaa
    12061 atccttgctt tcggtgtgcc gtccggccaa gtggagcttg cccggatatg tacgtatatt
    12121 catcacgacg agtttttctc ggcaaggcgt ttgggcatta agtccggacg gattctgtcg
    12181 gggatcatga ttcataaata atagacttga acgtaagttg atataaactt gaataaaagt
    12241 atgtttgaaa taaaagtatc tcaggaaata aagaacacct gccctgtttt tgccggagca
    12301 gccgtatatg cagcagtgaa gaatactgct tactgcgatg gactttggaa agaaataaat
    12361 actttcacag aagacttgac taccaccacc caaatggcag acattaagtt gcaacctgtg
    12421 attgctgcta cccgtgaggc ttataagcgt tgcggaaaag atccggggcg ttatcgtccg
    12481 tcggcagaag cgctgcgccg tcgcctgatg cgtggcatcc ctttgtatca gattgatact
    12541 ttggttgacc t
//
