LOCUS       c00625_gnlPro..        11634 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DODPMHAE_625.
ACCESSION   c00625_gnlPro..
VERSION     c00625_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 19:17:20
            Original ID  :: gnl|Prokka|DODPMHAE_625
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11634
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11634
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[5381:11367]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      5382..11367
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..11634
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..11634
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(3..1583)
                     /locus_tag="ctg625_1"
                     /transl_table=11
                     /translation="MKRFINISFLSLVFAGMALTGCNDDLTTSSYVKVNDEDVLGNVSQ
                     LEKVLTSAYKQLYFNTDKGDRVYAGLPGFQMYVDASGADVISHTNMGGDQVTAYQYSNS
                     KTQADGNASKIWSMCYNVINRANIILTNVDAAAGDETQKKHIKGQALAMRGIQYFHLIQ
                     NYQQTYAIAKSKRGVILRTSSDDESHKGFSTVEEVYTQIVSDLTTAKTLLADYNPDDMW
                     LINSKICSGILARVYLVMQNWDGAYNEAKIVYDQHSQLMTREQYRSGFDDMISGNYAEV
                     VWAMKYTADNNLGGSTQFNFWYNQDASYGEGYADGPIYSFLDYFVDEQFVKLFEEKEDR
                     YQFWKRTNNANTEINTKWAFDKYKHYGEDGGSVIQSATRPEVCLMRGAEMLLIMAEAAA
                     QKGNSGEALNLLNRLQVARNATPTTNAGGEALLEDIYVERRKELICEGQAGFYDLVRLQ
                     KRLVRIGESTTNPAGHYVWGMQYLNGYNALDPQPIGTLESNDYRFFCQIPQMEILNNDA
                     ISESDQNPWS"
     CDS             complement(1602..4880)
                     /locus_tag="ctg625_2"
                     /transl_table=11
                     /translation="MISVLLGAAGAIAANPTGPETMVVQQGNKVTGLVEDQMGPVAGAS
                     VVVKGTTIGTITDIDGKFTLDNVRRGAVIVISFVGLATQEITWNGQSILNVKLSDATQD
                     LDEVVVVAYGTAKKSTFTGSASVVKAEKLEKIMGSGFAEALQGMSAGVNVVNVQGNPGA
                     DARVEIRGIASMSGKADPLYIVDGMPYDGKLNQINPTDIESMTVLKDAAATSLYGSRAA
                     NGVVMITTKRGKSEKPRINFRGGWGTSDNAVKNPKKADPYQQLENTWYALYYDALLYDG
                     MNMQQAGDYASSQALTKQVKATKDSNGNLIYVTPFRHINENYVLHDGNGNPYMNPNLEY
                     VWDEDDWDVYKAIFSRKLRQDYSVDISGQANGGKTAYFFSGGYLDDQGYGNRQYYKRYS
                     FRTNLSTELFDWWKVAGSLSYSRHRQNLSGGASRAANFTTTLSSPWLRNEDNTGWVVSE
                     KTGERMYSYGKYTNNFFGAHILNNSGDYWDNPNDDSFDNNMGHILSAQVNTEFTLPFNL
                     KFRSALNIDDYWYRTMQYTSAVHGSGQTAPYGISILADGGYASRYNFNKRSTTWNNVLS
                     GEWMIGDHTISGLVGHEWYTWDSHYEQGWGEGIMELGKYELSNTTKNFGVSGGRDKYSL
                     LSFFGKVDYNFLNKYYLSASLREDGSSRFSSDHRWGTFWSTGGSWRISKEGFMEDLKWI
                     DNLSLRGSYGTTGNDKLIVRESNGKAGDEVLYGYQGTYESDDLYLKSGLKPSTYPTPDL
                     KWESNQQWNIGLDFSVFNRLSGTVEYYSRTSHDLLYYKELPLSAQVGSASGYNMNIGDL
                     RNSGIEITLNANILTTKDFRWDIDANMSTLKNEVTYLPTGPYTYSGTACTYKMEEGKSL
                     YEFIAPQYDGVNPETGVPGWLIRDGNGGWKRTEKQEEVTTDDFVYCGSAIPKVFGAITN
                     NFQFKGIDLSFMFYYSYGSKISDYTYKERIMNRPGVGVIQELVEDRWRQPGDADVLIPR
                     WSYNQYGATVKYADNFVFDNHYWRLRNLTLGYTLPKSLTRKALVENLRVYVTGNNLLTF
                     GPAKKRYTDPETGIMGNSYNGNAETDNGIQGSRRLYMVGIQITL"
     CDS             complement(5382..6428)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg625_3"
                     /sec_met_domain="IlvN (E-value: 8.5e-49, bitscore: 154.2,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 2e-44, bitscore: 140.3,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVMNFGGVDENVVTREEFPLEKAREVLKDETIAVIGYGVQGPGQ
                     SLNLRDNGFNVIVGQRKGGKTWEKAVADGWVPGETLFDIEEACEKATIIQYLLSDAAQI
                     EVWPRIKKYLTPGKALYFSHGFGITYKERTNIIPPADVDVILVAPKGSGTSLRRMFLQG
                     RGLNSSYAIFQDATGKAWDRVIALGIGVGSGYLFETTFKKEVYSDLTGERGTLMGAIQG
                     LLLAQYETLRENGHEPSEAFNETVEELTQSLMPLFAENGMDWMYANCSTTAQRGALDWM
                     GPFHDATKPVFQKLYSEVACGNEAQRSIDTNSKPDYREGLEKELAALRESEMWRAGAVV
                     RKLRPENN"
     CDS             complement(6470..7201)
                     /locus_tag="ctg625_4"
                     /transl_table=11
                     /translation="MEKNKVGEFHFVTESYLTDFRGRITIPMIGTYLLHAASCHAADRG
                     FGYNDMTERHTAWVLSRLAIEMTSYPAMSESVTLYTWVDEVGKLFTSRCFELVNGEGKT
                     FGFARSIWAAIDMETRRPTLLDVEGLSAYITDRPCPIEKPGKIAPVENNTSGEPYRVKY
                     SDLDVNGHLNSIKYMEHLLDLFDISLFREKEISRFEIAYQSEGKYGMELTLHNQEVSLD
                     KYNMAICNDGKAISRAAVTWI"
     CDS             complement(7238..7792)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg625_5"
                     /sec_met_domain="ALS_ss_C (E-value: 7.9e-19, bitscore:
                     56.7, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTKQLYTVIIFSENTVGLLNQITVIFTRRQLNIETLSVSPSAIK
                     GIHKFTITTFADEDTIDKVVKQIDKRVDILKAYYNTDEDLVYQEIALYKLSTELFIKMG
                     TVEDLIRKYNARILEMNEDCVVLEKSGHYDETQALFKELSETIGVLQFIRSGRVAITKS
                     KVERLSDMLSAMEKKLQEKHV"
     CDS             complement(7805..9505)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg625_6"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.4e-51, bitscore:
                     162.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKQKITGSEALLKALIAEGVDTIFGYPGGQAIPIYDSLYDYRDQ
                     LKHILVRHEQGATHAAQGYARVSGKVGVTVVTSGPGATNTITGIADALMDSTPMVVIAG
                     QVPSPLLGTDAFQEVDVIGITQPITKWAYQIRRPEEIAWAVSRAFYIASTGRPGPVVLD
                     LAKDAQVGLVDYEYQKVDYVRSYQPEPDIREERIEAAASLINNAKKPFCLVGQGVILGG
                     AEEELKEFLLKNDIPAGSTVLGLSALPSDFPLNKGMLGMHGNVGPNRKTNECDVLIAIG
                     MRFDDRVTGDLKTYAKQAKIIHLDIDNSEIGKNVPVDVKVLGNAKHTIPMITALLEERK
                     RPEWNAEFEPDEKEEYNKVIEKELYPTEGQLKMGEVVRKVSEATDNDAILVTDVGQNQM
                     MGVRYFKYKQTRSVVTSGGLGTMGFGLPAAIGAKLGAPDRTVCFFTGDGGIQMTIQELG
                     TIMQENLNVKIIVLNNNFLGMVRQWQELFFNERYSNTIMKNPDFVAIAKAFGIASRAVD
                     KREDLDEAIAEMLNHDGAYMLVANVETCGMVYPMVPAGGSVTNMILGDK"
     CDS             complement(9532..11367)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg625_7"
                     /sec_met_domain="ILVD_EDD (E-value: 1.8e-218, bitscore:
                     715.1, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMKNPLRSSYSTEGRRMAGARALWRANGMKEEQFGKPIIAIVNSF
                     TQFVPGHVHLHEIGQQVKAEIEKLGCFAAEFNTIAIDDGIAMGHDGMLYSLPSRDIIAD
                     SVEYMVNAHKADAMVCISNCDKITPGMLMASMRLNIPTIFVSGGPMEAGNLDGRALDLI
                     DAMIEAADDSISDEQVEKVERSACPTCGCCSGMFTANSMNCLNEAIGLALPGNGTVVAT
                     HANRTRLFKKAAKMIVDNAFKYYRDGDDSVLPRSIATRQAFLNAMSLDIAMGGSTNTVL
                     HLLAVAHEAEVDFTMKDIDMLSRKTPVICKVAPSCSYHVEDVNRAGGIIGIMNELVKAG
                     LVDGSVKRADGLTLNEAIDQYCITSVNVTEEAINIYKSAPAHRFNLVLGSQESYYKELD
                     TDRATGCIRDVEHAYVKDGGLAVLYGNIAQDGCVVKTAGVDESIFRFAGPAKVFDSQDA
                     ACEGILKDQVVSGDVVVITYEGPKGGPGMQEMLYPTSYIKSKHLGKECALITDGRFSGG
                     TSGLSIGHISPEAAAGGAIGLVKDGDIIEINIPERTIHVKVTDEELAKRREAEEARGTK
                     AFTPPFRQRTVSKALKAYAKMVASADKGGVRIVED"
ORIGIN
        1 ccgctccacg gattctgatc tgattcggag atcgcatcat tattcaggat ttccatttgc
       61 gggatttggc agaagaaacg gtaatcgttc gactccagcg tccctatcgg ttgcggatcg
      121 agcgcattat atccgttcag atactgcatg ccccatacgt aatgtccggc aggattggta
      181 gttgattcac cgatacgaac caatctcttt tgcaggcgca ccaggtcata aaaaccggct
      241 tgtccttcac agatcaactc tttacggcgt tccacataga tgtcttccag caaagcttcg
      301 cctccggcat tggttgtcgg ggtagcatta cgcgccacct gcaaacggtt cagcagattc
      361 agggcctcac cggaattacc cttttgggct gcagcttcgg ccatgatcag cagcatttct
      421 gctccgcgca tcaggcagac ttctggacgg gtagcgcttt gaataacgct tccgccgtct
      481 tcaccataat gcttgtattt gtcgaaagcc cattttgtat tgatttccgt attcgcattg
      541 ttcgtacgtt tccagaactg gtaacggtct tctttttctt caaatagttt cacaaactgc
      601 tcatccacga agtagtcaag gaacgagtag ataggaccat cggcataacc ctcgccgtag
      661 ctggcatcct ggttatacca gaaattgaac tgcgtactac cgcccaggtt attatcggcg
      721 gtatatttca tggcccatac cacttccgca taattgccgg agatcatatc gtcgaaaccg
      781 gaacggtatt gttcgcgggt catcaactgg ctgtgctggt cgtagacgat cttggcttca
      841 ttgtaagcgc cgtcccagtt ctgcatcacc agataaacac gggccaggat tcccgaacat
      901 attttggagt tgatcagcca catatcgtcc ggattataat cggcaagcaa tgttttagcc
      961 gtcgtcaggt cggacacaat ctgggtatag acttcctcta cagtagaaaa acctttatgg
     1021 gattcatcat cggaagaggt acgcaggatc accccacgct tgcttttagc tatcgcatac
     1081 gtctgctggt aattctggat cagatggaaa tactggattc cacgcatcgc caacgcctgg
     1141 cctttgatat gttttttctg tgtttcatca ccggcggcgg catccacatt ggtcaggatg
     1201 atattggcac ggttgatcac attatagcac atcgaccaga tttttgaggc atttccgtca
     1261 gcctgtgttt ttgagttgga atactggtat gctgttacct gatcacctcc catattggta
     1321 tggctgatca cgtcggcacc actcgcatcg acatacatct ggaatccggg aagaccggca
     1381 tacacacggt cgcctttatc ggtattaaaa tacagctgct tataggctga agtcaatact
     1441 ttttccaact gggagacatt ccccagtaca tcttcatcgt ttactttcac gtaggagctg
     1501 gttgtcaggt cgtcgttaca tccggtcagg gccataccag caaaaaccag ggacaggaag
     1561 gatatattta taaatcgttt cataaatatc attttttacg tttacaatgt gatttgaata
     1621 ccgaccatat acagtcttct cgaaccctga ataccgttat cggtttcagc attaccgtta
     1681 taactgttac ccattatacc tgtttcgggg tctgtgtagc gttttttggc aggaccgaaa
     1741 gtcaacaggt tattaccggt tacataaaca cgcaggtttt ctaccagggc cttgcgggta
     1801 aggctcttag gcagcgtata gcctaatgtc aggtttctca gacgccagta gtggttgtcg
     1861 aatacgaagt tatctgcata ttttaccgtc gcgccatact ggttgtacga ccaacgtggg
     1921 ataagcacat ccgcatcgcc cggctgacgc catctgtcct caaccaactc ctgtatcaca
     1981 ccgacacccg gacggttcat gatacgttct ttatatgtat agtccgatat tttggaacca
     2041 taagaataat agaacatgaa cgacaggtcg atccctttga actggaagtt attggtgata
     2101 gcaccgaaca ctttgggaat cgcggagcca cagtacacaa aatcgtctgt cgttacttct
     2161 tcctgctttt ccgtacgttt ccaaccgccg ttaccatcgc ggatcaacca gccgggtact
     2221 ccggtttccg gattaacacc atcgtactgg ggagcgataa attcatacag agacttgcct
     2281 tcctccatct tgtaggtaca ggcggtacca gaataagtgt aaggacctgt aggcaaataa
     2341 gtcacctcat ttttcagcgt actcatgttg gcatcgatat cccatctgaa atctttcgtt
     2401 gtaaggatat tcgcattcaa tgtgatttca atcccgctat tacgcaggtc accgatattc
     2461 atattatacc cggatgcact accaacctgg gcagagagag gcagttcctt ataatacaac
     2521 aagtcatggg aagtacggga ataatattcc actgtaccgc taagtcggtt gaatacggag
     2581 aaatccaaac cgatattcca ttgctgatta ctttcccact tcaagtccgg tgtcggatag
     2641 gtagatggtt ttaaaccgga tttcagatac aggtcatcac tttcataagt accctggtat
     2701 ccgtaaagga cttcatcccc tgccttacca ttcgattcac gcacgatcag cttatcatta
     2761 ccagtcgtac cgtaactacc acgcaacgaa aggttatcaa tccatttcag gtcttccata
     2821 aaaccttctt tcgatattcg ccatgaaccg cctgtcgacc agaatgtacc ccagcgatga
     2881 tcggagctga aacgggaaga accatcctca cgaagtgaag cggacaagta atacttattc
     2941 aagaagttat aatcgacttt accgaagaac gaaagcagag agtatttatc acgtccgccg
     3001 gaaacaccga agttcttggt ggtattcgat aattcatatt tacccagttc catgatacct
     3061 tcaccccaac cttgttcgta gtgggagtcc caggtatacc actcatgtcc gaccagacct
     3121 gaaatcgtat ggtcaccaat catccattca ccagacaata cattattcca ggtggtggaa
     3181 cgtttattga aattataacg gctggcataa ccaccgtctg ccagtataga aataccataa
     3241 ggtgcagtct gtccgctgcc atgtacggcg gaagtatatt gcatggtacg ataccagtaa
     3301 tcgtcaatat tcaaagccga acggaatttc aggttgaaag gaagagtaaa ctctgtattt
     3361 acctgggcag acaggatatg ccccatattg ttatcgaaac tgtcatcgtt cggattatcc
     3421 caataatcac ccgagttatt caggatatgg gcaccaaaga agttattggt atatttaccg
     3481 taactgtaca tccgttcccc tgttttttca gaaacgaccc aaccggtatt atcttcatta
     3541 cgtaaccagg gtgaagacaa agtcgtcgta aagttagccg cacggctggc accaccggaa
     3601 aggttctggc gatgacgcga ataagaaagg ctaccggcca ctttccacca atcgaacaac
     3661 tctgtactca ggttggtacg gaaagaataa cgtttataat actgccggtt accatatccc
     3721 tggtcgtcca gataaccgcc ggagaagaaa taggctgttt ttccaccatt ggcctgacca
     3781 cttatatcca cactataatc ctggcgcagt ttacgggaga agatagcttt gtagacatcc
     3841 caatcatctt catcccagac atattccaga ttaggattca tgtaaggatt cccattgccg
     3901 tcatgcaata cgtaattttc attgatatgt ctgaacggag tgacataaat cagattacca
     3961 ttcgaatctt ttgtagcctt tacctgtttg gtcaatgcct gcgacgaagc ataatcgccc
     4021 gcctgttgca tattcatgcc gtcataaaga agggcatcat aatacaaggc ataccaggta
     4081 ttttccagct gctggtacgg atcggctttt ttcggattct tgacagcatt atccgaagta
     4141 ccccaacctc cgcggaagtt aatacgcggt ttttctgatt taccccgctt ggttgtaatc
     4201 attacgacgc cgtttgctgc acgcgaaccg tagagcgaag tggccgccgc atccttcagc
     4261 accgtcatcg attctatgtc cgtaggattg atctgattca gttttccatc gtaaggcatc
     4321 ccgtccacaa tatataacgg atcggccttt ccggacatgg aagcaatacc acggatctcc
     4381 acacgggcat cagctccggg gttaccctgt acattcacaa cattcacacc ggcactcatc
     4441 ccctgcaatg cttccgcaaa gccggagccc atgatctttt cgagtttttc agcttttaca
     4501 acggaggccg atccggtgaa ggttgatttc ttagccgttc cataggctac gacaacgact
     4561 tcatccaggt cctgtgtcgc atcacttaat tttacattta aaatagattg tccgttccaa
     4621 gtgatctcct gagtggccag gccgacaaag gaaataacaa taaccgctcc ccgccgaaca
     4681 ttatccagcg taaactttcc atcgatatcg gttatcgtac cgatagtggt tcctttcact
     4741 acaacagaag ctccggcgac aggtcccatc tggtcctcta ccaggccggt taccttatta
     4801 ccctgttgta ctaccatcgt ttccggacct gtaggattgg cagcaatcgc acctgccgca
     4861 cctaataata cagaaatcat tagtgatcta attagttttg agttggtcca catagctaaa
     4921 ttcaagtctt taattaaata aaattaatca caatagcgtt catttcatta gaggttacac
     4981 ttttctaaga taaaagtgac tggcatacat ttcaataaaa taaagttaac taaaacaaag
     5041 atatactgat cattacacac aacatccttc tatatttcca ctctacaaac tacagtatct
     5101 ccatcagcaa atataactta tcattattta atacaagcat aattatgtat atttattgct
     5161 ctaataaata tattttaacc accatttaat tgattttttt atctaaaatc cacattcaaa
     5221 caatgacata catattggga tgaaaaatca ataacagttg caatcaaaaa cattttttaa
     5281 ccattaacgc attacataaa ccataaaaaa acggcaaccc gaaaagccgg attgccgttt
     5341 ttatatcaca aaatgtttaa ctattaatgt atcaccattt attagttgtt ttcaggacga
     5401 agtttacgaa caacagcacc tgcacgccac atttcacttt cgcgaagagc agccagttct
     5461 ttttccagac cttcacgata gtcaggcttg ctgtttgtgt cgatagaacg ctgtgcttcg
     5521 ttaccgcagg caacttcgct atacaacttc tggaacaccg gttttgtagc atcgtggaac
     5581 gggcccatcc agtccaaagc accacgctgt gcagttgttg aacagtttgc atacatccag
     5641 tccataccgt tttctgcgaa caacggcatc aatgactgag tcagttcttc tactgtttca
     5701 ttgaatgctt cagaaggttc gtgaccgttt tcacgcaaag tttcgtactg agccaacagt
     5761 aatccctgga tagctcccat caaagtacca cgttcgccgg tcaggtcaga ataaacttct
     5821 ttcttgaatg ttgtttcaaa caagtaacca gaaccaacac cgatacccag tgcaatcacg
     5881 cgatcccatg ctttgcctgt tgcatcctgg aagattgcgt agcttgagtt cagaccacga
     5941 ccctgcaaga acatacggcg cagtgaagta cctgaacctt tcggagcaac caggattacg
     6001 tctacatcag caggagggat gatgtttgta cgttctttgt aagtgatgcc gaatccgtga
     6061 gagaaataca aagccttacc cggagtcagg tattttttga tgcgcggcca aacttcaatc
     6121 tgagcagcat ctgaaagcag atactggatg atagttgctt tttcgcatgc ttcttcgata
     6181 tcgaacagtg tttcgcccgg tacccaaccg tcagcaacgg ccttttccca ggtcttacca
     6241 cctttacgtt gtcctacaat tacgttaaaa ccgttgtcgc gcaggttcag gctctggcca
     6301 ggaccttgta cgccgtaacc tattacagcg attgtttcgt ctttcaatac ttctcttgcc
     6361 ttttccaacg gaaattcttc gcgggttact acgttttcgt caacgccgcc aaaattcatt
     6421 actgccattt tctttttact attaaaatgt atataaaata atttgttttt cagatccagg
     6481 taacggcagc gcggctgatg gctttgccgt cgttacagat tgccatatta tatttatcga
     6541 gggatacttc ctggttatgg agagtcagct ccatcccata ctttccttcg gactgataag
     6601 ctatttcgaa acggcttatc tctttttctc ggaacaggct gatatcgaac aagtcgagca
     6661 ggtgttccat gtatttgata ctgttcaggt ggccgtttac gtccaggtca ctatacttca
     6721 cacggtaagg ttcgccggaa gtgttgtttt ccaccggagc aattttaccc ggtttttcaa
     6781 tcggacaggg acggtcggtg atataagcac tcaggccctc cacatcgagc aaggtcgggc
     6841 ggcgggtttc catatcgata gccgcccaga tagagcgggc aaagccaaag gtcttgcctt
     6901 cgccgttcac cagttcaaag caacggctgg taaacaactt accgacctca tccacccagg
     6961 tatataaagt tacggattca gacatggcag gataagaagt catctcgata gccagacggg
     7021 aaagaaccca ggcggtatgc ctttcggtca tatcgttata tccgaatcca cggtcggcgg
     7081 catggcaaga agcagcatgc aacaaataag ttccgatcat agggattgta atacgtcccc
     7141 ggaagtccgt cagataagac tctgttacga aatgaaattc tcctactttg ttcttctcca
     7201 taatttactt tatttacaaa atgtttcctt attattctca gacatgtttt tcctgcaact
     7261 tcttttccat tgcagataac atgtcgctca gacgttctac cttactcttc gttatagcaa
     7321 cgcgtccgga acggataaat tgcaggacac cgatcgtctc actcaattct ttaaacaaag
     7381 cctgtgtctc atcataatga ccactctttt ccaacaccac acaatcctca ttcatttcaa
     7441 ggatacgggc attgtactta cggatcagat cctcaaccgt ccccatcttg ataaagagtt
     7501 cggtactcag tttataaaga gcgatttcct ggtaaaccag gtcttcatcc gtattataat
     7561 aggctttcag gatatccaca cgcttgtcga tctgttttac gaccttgtcg atcgtatcct
     7621 cgtcggcaaa ggtagtaatt gtaaacttat gtattccctt tatagcagag ggagaaacag
     7681 aaagcgtctc aatgttcagt tgccggcgcg taaagataac agttatctga ttcagaagac
     7741 caacagtgtt ttccgaaaag ataataacgg tatataattg ttttgtattc atagtttctc
     7801 ctccttactt atcacccaaa atcatgtttg tcacgcttcc tccggccgga accatcggat
     7861 ataccatacc acaagtttcc acattggcaa ccaacatata ggcaccatcg tgattcaaca
     7921 tttcagcaat cgcctcatcc aagtcttccc gtttatctac cgcacgggaa gcaataccaa
     7981 aagccttggc tatcgctaca aaatccggat tcttcatgat ggtattcgaa taccgttcgt
     8041 tgaagaacag ctcctgccac tggcgtacca ttcccaggaa attgttgtta agaacgatga
     8101 tctttacatt cagattttcc tgcatgatag ttcccaactc ctggatagtc atctggatac
     8161 caccgtcgcc ggtaaagaaa cagaccgtac ggtcaggcgc tcccagcttc gctccaatgg
     8221 cggcgggaag gccaaagccc atcgttccca aacctcctga agtaactacg ctgcgtgttt
     8281 gtttatattt gaaatagcga acacccatca tctggttctg acctacatcc gtaaccagaa
     8341 tcgcatcatt atcggttgct tcggaaacct tacggactac ttcgcccatt ttcagttggc
     8401 cttcggtagg atagagttct ttttctatta ccttattata ttcctctttt tcatccggtt
     8461 cgaattcagc attccattcc ggacgcttcc gttcttccag taaagccgta atcatcggaa
     8521 tcgtatgctt ggcatttccc agcactttca cgtcgaccgg cacattcttt ccgatctccg
     8581 aattgtcgat atccaggtgg ataatctttg cctgcttggc ataagtcttc aggtcgccgg
     8641 ttacacggtc atcgaaacgc ataccgatag caatcagcac gtcacattcg tttgtcttgc
     8701 ggttcggtcc gacatttcca tgcatcccca acataccttt atttaatggg aagtccgaag
     8761 gtaatgcaga caagcccaat acggtagaac cggctggtat atcgtttttc aacaagaatt
     8821 ctttcagttc ttcttcagct cctcccagga taaccccctg ccctaccaga cagaatggct
     8881 ttttggcatt atttatcaat gaagcagccg cctcgatacg ttcctccctg atatccggtt
     8941 caggttggta actacgaaca taatccactt tctgatactc ataatctacc aaacccacct
     9001 gtgcatcttt cgccaaatcc agtaccacag gtcccgggcg accggtcgat gcgatataga
     9061 aagcacggga aacggcccaa gcaatttctt ccgggcggcg tatctggtaa gcccatttgg
     9121 taatcggttg tgtgataccg atcacatcaa cttcctggaa agcatctgtt ccaagcagcg
     9181 gagacggaac ctggccggca atcaccacca tcggtgtact gtccatcagc gcatcggcaa
     9241 taccagtgat ggtattggtt gccccgggac ccgaagtaac caccgttact cccacttttc
     9301 cggaaacacg ggcatatccc tgtgcagcat gtgttgcacc ttgttcgtgg cgcaccagaa
     9361 tatgttttaa ctgatctctg taatcgtata aactatcgta aattggtatc gcctgcccac
     9421 ccggataacc gaagatagta tctactcctt cagcgatcag cgctttcagc aaagcttccg
     9481 aaccggttat cttttgtttg tccatctcta aaatatagta tttggtgttt attaatcttc
     9541 tactattcgt acaccgccct tatcggccga agcaaccatc tttgcatatg ctttcagtgc
     9601 tttcgatacc gtacgttggc ggaaaggagg tgtaaaggct tttgttccgc gggcctcttc
     9661 cgcttcacgg cgtttggcca gttcttcgtc tgtcaccttt acatgtatgg ttctttcggg
     9721 aatattaatt tcgataatat cgccgtcttt cactaagcca atcgctccgc ctgcagccgc
     9781 ttcgggagaa atatgtccga ttgacaaacc tgatgttcca ccgctgaagc gtccgtctgt
     9841 gattagcgca cattctttac ccaggtgttt actctttata taagaggtag gatacaacat
     9901 ttcctgcata cccggaccac ccttaggacc ttcataggtg ataacgacga catcgccgga
     9961 gacgacttga tctttcagga taccttcgca agcggcatcc tgcgaatcga atactttggc
    10021 agggccggca aaacggaaga tactttcatc taccccggct gttttaacca cacaaccgtc
    10081 ctgtgcaata tttccataca gaacagccag accgccgtct ttcacataag catgttccac
    10141 atcgcggata catccggttg cacggtcggt atccagttct ttataataac tttcctgcga
    10201 tccgagcacc agattgaaac ggtgggccgg agcactttta taaatattga ttgcttcttc
    10261 cgttacattt acagaggtaa tgcagtattg gtcgatagcc tcattcaaag tcagaccatc
    10321 cgcacgtttc acggaaccgt ccaccagacc ggcttttacc agctcattca taataccgat
    10381 aatacctccg gcacggttca catcttccac atgataagaa caactcggag ccactttaca
    10441 gataaccggt gttttgcgtg aaagcatatc gatgtctttc attgtaaaat cgacttccgc
    10501 ttcatgagcc acggccaaca ggtgaaggac tgtattcgtc gatcccccca tggcaatatc
    10561 cagcgacata gcattcagaa aggcctgacg ggtggcaata ctgcgaggca atacggaatc
    10621 atcgccgtca cgataatatt taaaggcatt atcaacaatc atcttcgcgg cttttttgaa
    10681 caggcgggta cggttggcat gtgttgcaac aactgttccg ttgccgggaa gagccaatcc
    10741 aatcgcttcg ttcagacagt tcatagagtt agccgtgaac ataccagaac agcaaccgca
    10801 ggtcgggcaa gcggaacgtt ccaccttttc tacttgttca tcgctgatag aatcgtcagc
    10861 cgcttcaatc atggcgtcga tcaaatcgag tgcacgtccg tccagattac cggcttccat
    10921 cggaccgccg gatacaaaga ttgtcggaat attcagacgc atactggcca tcagcatacc
    10981 cggagtaatc ttgtcgcagt tactgataca aaccattgca tcagccttat gcgcattcac
    11041 catatattcc acactgtcag caatgatgtc gcgggaaggc agagaataaa gcattccgtc
    11101 gtgtcccata gcaataccgt catcaatagc gatcgtatta aattctgcgg caaagcaacc
    11161 gagcttttcg atttccgctt ttacctgctg tccgatctcg tgtagatgca catggcccgg
    11221 tacaaactgg gtaaatgaat tcacaatggc aatgatcggt ttaccgaact gttcttcttt
    11281 catgccgttg gcacgccata atgcacgggc tccggccata cgtctgcctt ctgtgctata
    11341 ggagcttctt aacggattct tcatcatatc tgtttttatc ttttagtcaa taaaaaagcc
    11401 cttctctata tggagaaagg cttaagaaat atcttttacg acttcacaac ttcttacaca
    11461 cctttctcct tacctactaa tgactagaag gaccaccacg agaataatat gtaatacatt
    11521 gttcatcatc ttttcttatc gtctttattt tgtttgacgc tgcaaatgta gaataataat
    11581 ttgtacgagc aaaggattta aaagaaaaat cttacttttt ctttcattta tcaa
//
