LOCUS       gnlProkkaDDDCDFAK_51   10693 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DDDCDFAK_51.
ACCESSION   gnlProkkaDDDCDFAK_51
VERSION     gnlProkkaDDDCDFAK_51
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-02 07:27:21
            Original ID  :: gnl|Prokka|DDDCDFAK_51
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10693
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10693
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[6181:6481]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      6182..6481
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..10693
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10693
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             235..531
                     /locus_tag="ctg51_1"
                     /transl_table=11
                     /translation="MANEYTPDLITLIGDDGKEIEFEILDIIENDEGKFYVLYPFFENP
                     EDAVNDSGEYYIFEVTEIDGEEELAEIEDDDKLDRIAAVFEERYNEEFYDEDD"
     CDS             834..1796
                     /locus_tag="ctg51_2"
                     /transl_table=11
                     /translation="MNISVLGCGRWGSCIAWYLDKIGHNVLSCGLADAPEFIQLKETHK
                     NDYLTFPKSIEVSSDLEYAIERAEVIIISISSQYLRSYFADISKYNLDGKTIVLCMKGV
                     EATTGKRLSEVVGEFVDESKTPVAVWVGPGHPQDYVRGIPNCMVIDSNNHDIKEKLVNE
                     FTSDLIRFYLGTDLIGSEIGAAAKNVIGIAAGMLDGLNYTSLKGALMARGTREIARLIK
                     ALGGNEMSAYGLCHLGDYEATLFSKWSHNRMYGESFAKGDRFTKLAEGVMTSKALYKLG
                     QEYGVDLPIVESVYKVLFDGTDIKEALGTLFMRSVKKEF"
     CDS             1814..3496
                     /locus_tag="ctg51_3"
                     /transl_table=11
                     /translation="MGNTKAKNNSNKPKQTGKTVTSVKKQNTVEYVIVNILCLFVFIAF
                     AYIAIMSFVQTSVFDSANYGSEVILYQTDNIALNILFTSLFTVFIFKMKKHCDFFAKVN
                     LKYMHIGLAAFVMIVGLVWIFSVTSVPAADSYNIYETASQAAKGNYSSFHNNSGFYNSD
                     FYSGYSYYNFYPFQLGFVFISEIFYRIFGTDSTMPIQVFNVMCTAAAYIGIVNITRLLF
                     KKRSVEFITILLLAGCFQPVLFCTFVYGNIIGMCFAIWASYFLIKYFQTNKYLLLIPCA
                     VLLVISTLAKYNNLIYLVAFVVMLIIHTIKAKKWQSIAFALAICIAVVGTSNLVIMSYE
                     NRSGVKLSSGVSQAMYLDMGINDSYMAPGWYNGIALNDYKSAGLDAKAANAQAWTNIKS
                     RMNYFGKNTNYMIDFFSKKIISQWNEPTYESIWVSKVKSHTNELNWIGNGMYDGSIGQF
                     FELYFNFYMQILFIAFAAGIYFLFINRKTNIETVLLPLVILGAFGYHLLFEGKSQYVLT
                     YIILMIPTASFAFECILNGKYTKIKEFVGKLKEIPDGKESEKA"
     CDS             complement(3518..4384)
                     /locus_tag="ctg51_4"
                     /transl_table=11
                     /translation="MVRIITDSAADFEHSESEKFGISTIPLAVYIDGKEYKDDFLHSKE
                     RFYRLAKLSKTLPKTSQPSPYVYECALKKARDNGESVVVITVSSALSGSYQSAVLARDL
                     LGYEGCYVIDSKSASAGQKLLVNEALRLRDNGFTAKEIAEHLLRFRSRIMVYACIDDMK
                     YLYGGGRHTNAAALLGSTGRIKPVISITGSGSVAFEAKTIGMRHGMNHMLMSLKKLGID
                     QNYPLYIMHTNAKNQALYLSKLIISKGIPFVEGSIVSVGSVVGSHIGEGSTGIAFVKKE
                     QRKSGHD"
     CDS             complement(4397..5710)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_5"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg51_5"
                     /sec_met_domain="NTP_transf_5 (E-value: 3.9e-39, bitscore:
                     124.0, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKHLNDNEKIEFKYLLELVSSSVNGTAPPIPYEGIKWQSIKMLA
                     NYCSVESLVANAVLSLDKKYVSPEVYEKFKQNLSLEMLIDGNLSYETEKILKAFDENKI
                     KNIPLKGYFMKKEYPRSDFRSVCDVDILFDRKQADSVKKVFSKLGYTFLNEDDNQYHFE
                     KKPIMNIEMHATLVHENEESYPLLVNQLDRSTKRDGYSYSYEMSHEDFYIYMLVHNSNH
                     FRIGGMGARMVLDSYVFLKNHQSELDYDYLNVMLEKIGIAKYEKRVREIAFNWFSKPHA
                     ELKFDDIEEYILLSGTLGRVDVGTMINSHKTITENNKSKFSYLVSSIFPPKSEMQYKYP
                     YVKKTPFLLPISWCHMWGKRLFVDRNINFKSGIKNRMSYTDEDVNLYKSLLDEMGFDGI
                     GINNFGNLICKSTTRQFLLSGFLHNKGKFENNISRYYF"
     CDS             complement(5707..6195)
                     /locus_tag="ctg51_6"
                     /transl_table=11
                     /translation="MSLNKEVGLDDVMQIIAEKLETGGSVTFNPKGTSMLPMLRDGDDT
                     VVLSKPKGRLHLFDLPLYRRKDGSYVLHRVVNFGSDGSYTMCGDNQFAVEKGITDDDVI
                     GVVTAFYRKGKPYTVDSMKYRAYLEFMFYSKPLRKVIASTMSRSKNAFSKLKTKKGKK"
     CDS             complement(6182..6481)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg51_7"
                     /sec_met_domain="PF05402 (E-value: 2.7e-17, bitscore: 52.4,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 2.8e-14,
                     bitscore: 42.5, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYEKFTRKTGDFMKIKEDFVLRKVADSYVVVPVNKLTLDFNGIIN
                     LNETGAFLFEKLQNDCEKADLLKAMLDEYEVSEDKASADIDTFIQKLREADVLE"
     CDS             complement(6598..8226)
                     /gene_functions="other (smcogs) SMCOG1299:chaperonin GroEL
                     (Score: 814.4; E-value: 5.8e-247)"
                     /gene_kind="other"
                     /locus_tag="ctg51_8"
                     /transl_table=11
                     /translation="MAKQIAYGEDARKALMKGIDQLADTVKITLGPKGRNVVLDKKFGA
                     PLITNDGVTIAKEIELEDPFENMGAQLVKEVSIKTNDIAGDGTTTATLLAQALIREGMK
                     NVTAGANPMVLKKGIADAVNVAVEAVKKNSKQVSGTDDIARVATVSSQDEFIGKLIAEA
                     MEKVTTDGVITVEESKTAETYSEVVEGMMFDRGYIAPYMVTDTDKMVAELDNPLILITD
                     KKISTTQEILPLLEQIVQMGKKLLIIAEDVEGEALTTLVLNKLRGTFTCVAVKAPGFGD
                     RRKEMLQDIATLTGGTVITSDLGLELKDTTVDQLGTARQVKIEKENTIIVDGSGDKEAI
                     KGRVAQIRQQIETTTSDFDREKLQERLAKLAGGVAVIKVGAATEVEMKEKKLRIEDALA
                     ATKAAVEEGIVAGGGIACMNAIPAVAEFVDTLEGDAKTGAKIVLKALEEPLRQIVANAG
                     LEGSVICDNVKKANKVGYGFNALTEEYTDMVSAGIVDPTKVTRSALQNASSVAAMVLTT
                     ESLVTDIKEPAAPAAPAAPDMGGMY"
     CDS             complement(8255..8539)
                     /locus_tag="ctg51_9"
                     /transl_table=11
                     /translation="MTIKPLLDRVVLKVEEAEEKTKSGIILSSAAQEKPQFASVVAVGP
                     GGVVDGKEVKMYVSVGDKVIASKYAGTQVKIDGEEYTIVNQSDILATLE"
     CDS             complement(8803..10509)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs)
                     SMCOG1030:serine/threonine protein kinase (Score: 81.2;
                     E-value: 1.5e-24)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg51_10"
                     /sec_met_domain="Pkinase (E-value: 2.8e-14, bitscore: 42.4,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFLWYNSFQTKFEIDTYLELSNNMSLCMGCMQEIGDNKICPSCGF
                     DTTEKQQAPFLPYGTILQNRYIVGAGIDTNGESTRYISHDKQTGDIVIICEFLPIGLFS
                     REEGTTEVRINYENRLVYNKLKDDFLNYYRILSELRELSALMNVHNIFEENNTVYVVEE
                     NEDLIPFEEYVERSNGHLEWDIARPLFMPVISALEALHKRGVGHYAIAPKNMYITASGK
                     IKISGFASENERKRGTPLKSQLFSGAAAPEQYDDNFPLDDITDIYGFCATLFYALTGHM
                     PKSAVERRKDSRLLMSTTTVKRLPPHVVSALANGLQVERENRITDFDELRSQLSVAHTA
                     KAIQDEISRTASMNLTKSERTRKTSNGMSHASIIIIAAAITVLVLGIAGVFWLMQNPLA
                     GMFSNNTDASVSSTQSTEWTGATVPNYIGMTYEEAVKSVDSNSSITIYRTFNDEYSDDY
                     AEGKIMSQTPAAGSKITQEDSVVVSVCVSKGSQMRTLPKVEGEKLDTVASDIAAQGLLA
                     TAEYEYSDKVAEGRVIRYKEHVEGDTLEYGSTVVLVVSKGKKQTSSQSSNR"
ORIGIN
        1 cacatagaaa ggaagttgtt agttaattaa tattgatata tgatttatcg tgtttatact
       61 ataccatacc ttttagtcat tgtcaacact tttttatcac tttttcaatt ttttaatact
      121 ttttaattat ttcaaccaaa agtgttaaac atcttgacta aacgctcaaa aaattgtaaa
      181 ataattacgg tgaaaaaagc aaacccaaat ttcttaaaaa ccggaggttc tggaatggct
      241 aacgaatata cacccgacct cattaccctt atcggtgatg acggtaaaga aatagaattt
      301 gaaattcttg atatcattga aaacgatgag ggcaagtttt atgtactcta cccgttcttt
      361 gaaaatcccg aggatgctgt aaatgattcg ggagaatatt atatttttga agttaccgaa
      421 attgacggcg aagaagagct tgccgaaatt gaggatgatg acaagctcga cagaattgcc
      481 gctgtttttg aagagcgtta caatgaagaa ttttatgatg aagatgacta acagttcatt
      541 tttctgcata taaatagtat tgcaggacta aagattaata agttttaatt cctgcccgat
      601 acgcgaatga ttttaaaata accctacaac atttaaatcg ggagcttagc tccattgaac
      661 ggtgtgcaga cctcccgttt tctcggaaga agggagcctg aagttcaagg gcgggcaccc
      721 acctgtcact caagtaggca ggttattgca aaaatcatac ggtcgggcgg gttttttatt
      781 gttattaaag ctataaaaaa tataaataat atataaacag gagtagtaat aatatgaata
      841 tttccgtttt aggttgcgga cgctggggca gctgcattgc ctggtatctc gacaaaatcg
      901 gtcacaatgt tttaagctgc gggcttgccg acgcacccga atttatacag cttaaagaaa
      961 cacacaaaaa cgactatctc acctttccaa agtcaattga ggtttcttcg gatcttgaat
     1021 atgcgattga aagagccgag gttattataa tttcgatttc atcgcagtat ctgcgttcgt
     1081 attttgcaga tatttcaaag tacaatcttg acggcaagac aattgtcctc tgcatgaagg
     1141 gtgttgaggc aactacaggc aaaaggctca gtgaggtcgt cggtgaattt gttgacgaaa
     1201 gcaagacacc cgttgcagtt tgggtaggtc cgggacatcc ccaggattat gtaagaggta
     1261 ttccgaactg tatggttatt gacagcaata atcacgatat taaggaaaag cttgtaaatg
     1321 aattcacaag cgaccttatc agattttacc ttggaacgga tcttatcggc agtgaaatcg
     1381 gtgctgccgc aaagaatgtt atcggcatcg ccgcaggtat gcttgacgga cttaactaca
     1441 cctcattaaa aggtgcgtta atggcaagag gcacacgaga gattgcaaga ctcattaagg
     1501 cactcggagg caatgagatg agtgcttacg gtctttgtca tctcggcgac tatgaggcta
     1561 ccttgttttc aaaatggagt cacaacagaa tgtacggtga aagctttgca aagggagaca
     1621 gattcacaaa gcttgccgag ggtgttatga catcaaaagc gttatacaag ctcggtcagg
     1681 aatatggtgt tgaccttccg attgttgagt ctgtatacaa ggttttattc gacggaacag
     1741 atatcaaaga ggcactcgga actctgttta tgcgttctgt caagaaagaa ttttaatcgg
     1801 gcaggtacat aatatgggta atactaaagc taagaacaat tcaaataaac ctaaacagac
     1861 tggaaaaacg gttacttcag ttaaaaagca gaatacagtc gagtatgtta ttgtaaacat
     1921 tctttgtctg ttcgtattca tagcatttgc atacatagca attatgagct ttgtgcagac
     1981 aagcgtgttt gattcggcaa attacggcag tgaagtaatt ttgtatcaga cggataacat
     2041 tgcgctgaac atcctgttca cttccctgtt taccgttttt atattcaaaa tgaaaaagca
     2101 ttgtgacttt tttgcaaagg tcaatctgaa atatatgcat ataggtcttg cggcattcgt
     2161 tatgattgtg ggacttgtct ggatattctc ggtaacctct gttcctgcgg ctgacagcta
     2221 caacatctat gaaacagcgt cgcaggcggc taagggcaac tattcgtcat tccacaataa
     2281 cagcggtttt tacaacagcg atttttacag cggatattct tactacaact tctatccgtt
     2341 ccagcttggc tttgttttca tcagcgaaat tttttacaga attttcggta cggacagtac
     2401 aatgccgatt caggtattca atgtaatgtg tacagccgcc gcttatatag gtattgtaaa
     2461 tatcacaaga cttcttttca aaaagcgttc ggttgaattt attacaattc ttctgcttgc
     2521 cggctgtttt cagcccgtac ttttctgcac attcgtttac ggcaacatca tcggaatgtg
     2581 ctttgcaatc tgggcatcat acttcctcat aaagtatttt cagacaaaca agtacctgct
     2641 cctcattccg tgtgccgtac ttctcgttat ttcaacactt gcaaaataca acaacctgat
     2701 ttatcttgtt gcgtttgttg ttatgctgat tattcacaca attaaggcta agaagtggca
     2761 gagcattgca tttgcacttg caatttgcat tgctgttgtc ggaacaagca accttgttat
     2821 catgagttat gagaaccgtt cgggagtgaa gctttcaagc ggtgtttcac aggctatgta
     2881 ccttgatatg ggcattaacg attcatatat ggctcccggt tggtacaacg gaattgccct
     2941 caacgattat aaaagcgcag gtcttgacgc aaaagccgca aatgcacagg cttggaccaa
     3001 tataaaatca agaatgaatt acttcggtaa aaacacaaac tatatgattg acttcttctc
     3061 gaagaaaatt atcagccaat ggaatgagcc gacatacgaa agcatatggg ttagcaaggt
     3121 caagtctcat acaaacgagc ttaattggat cggcaacgga atgtatgacg gcagtatcgg
     3181 acagttcttt gaactgtact tcaacttcta tatgcagatt cttttcattg cgtttgcggc
     3241 aggaatttac ttcttgttca ttaacagaaa gacaaatatt gaaaccgtac ttctccctct
     3301 tgttattctg ggagcgttcg gatatcacct cttatttgaa ggcaagtcgc agtatgtgct
     3361 gacttacata attcttatga ttcctactgc gtcttttgca tttgagtgta ttcttaacgg
     3421 caaatataca aaaatcaaag aatttgtcgg aaagcttaaa gaaattcctg acggtaaaga
     3481 aagcgaaaaa gcctgataaa atgattgaag cggacagtta atcatgtccg ctttttcttt
     3541 gctctttttt gacaaatgca atacccgtac tgccctctcc tatatgactg ccgacaacgg
     3601 aacctacgct gacaatactg ccctcaacaa aaggaattcc ttttgatatt atgagctttg
     3661 ataaatacaa tgcctgattt tttgcgtttg tgtgcattat atacagcgga taattttggt
     3721 ctatgccaag ctttttcagc gacatcagca tatgattcat accgtggcgc attccgattg
     3781 ttttcgcctc aaaggctaca ctgcccgaac ccgtaatgct gattacgggt tttattcttc
     3841 ctgttgagcc gagtaatgcg gcggcatttg tatgtctgcc acccccatag aggtacttca
     3901 tatcgtcaat acaggcatat accataattc tgcttctgaa cctcagaaga tgttcggcaa
     3961 tttcttttgc tgtaaacccg ttgtcacgca ggcgaagtgc ctcgtttaca agaagcttct
     4021 gacctgccga agcagatttg ctgtctatca cataacaccc ctcatatccg agcaaatccc
     4081 ttgcaagaac tgcactctga tatgaaccgc tcaatgccga agaaacagtt atcaccacaa
     4141 ccgattcgcc gttatctctc gcctttttca aagcacattc gtagacatac ggcgagggtt
     4201 gagaggtttt cggcaaagtt ttcgacagct ttgcaagcct gtaaaagcgt tcctttgaat
     4261 gtaaaaaatc atccttatat tcttttccgt caatatacac agctaacgga attgtagaaa
     4321 ttccgaattt ttcactttct gaatgttcaa aatcggcggc tgaatcggta ataattctga
     4381 ccatttaggt atcacctcaa aaataatatc ttgaaatatt attttcaaat ttacctttat
     4441 tatgcaaaaa tcccgacagc aaaaactgtc gggtggttga tttgcatatt aaatttccga
     4501 aattatttat cccaataccg tcaaagccca tttcatccaa aagggacttg tacaaattta
     4561 catcttcatc cgtgtatgac atacggtttt tgatacccga tttaaaattg atatttctgt
     4621 ctacaaaaag cctttttccc cacatatgac accatgaaat cggtaaaagg aacggtgttt
     4681 tttttacata cggatacttg tactgcattt cggattttgg tggaaatatt gaggacacaa
     4741 gatatgagaa tttagattta ttattctctg taattgtctt gtgagaattt atcatcgtgc
     4801 cgacatctac cctgccgagt gtaccgctga gcagaatata ttcttcgata tcatcaaatt
     4861 taagttcagc atgtggcttt gaaaaccagt tgaacgcaat ctcacgaaca cgcttttcat
     4921 actttgcaat accgattttt tcaagcataa cattaagata gtcataatca agctcagatt
     4981 gatgattttt caagaaaaca tagctgtcaa gcaccattct tgctcccatt ccgccgattc
     5041 tgaaatgatt cgagttatga acaagcatat agatataaaa gtcctcatgg ctcatttcat
     5101 atgaatagct gtagccgtca cgctttgttg aacggtcaag ctgattaaca agcaacggat
     5161 aagattcctc attttcgtgg acaagagttg catgcatttc aatgttcata atcggctttt
     5221 tttcaaaatg atactggttg tcatcttcat tcagaaaagt gtatccgagt ttggaaaata
     5281 cttttttgac cgaatcagcc tgttttctgt caaaaaggat atctacatca cacacggaac
     5341 gaaagtcgga acgaggatat tcctttttca taaaatagcc ctttaaggga atattcttga
     5401 ttttgttttc atcaaaagcc ttgagaattt tctcggtttc atatgagaga tttccgtcaa
     5461 tcagcatttc aagcgacaaa ttctgcttga atttttcata tacttcgggc gaaacatact
     5521 ttttgtcgag cgacaaaacc gcattggcaa caagcgattc gacactgcaa tagtttgcaa
     5581 gcatttttat cgactgccat tttatcccct cataaggaat cggaggtgct gttccgttta
     5641 cagacgatga aacaagctca agcagatact taaattcaat tttttcgtta tcgttaagat
     5701 gtttcctcat tttttccctt ttttcgtttt aagctttgag aatgcatttt tacttcttga
     5761 catagttgat gcaataacct tccttagcgg ttttgaatag aacataaatt caaggtatgc
     5821 tctgtacttc attgagtcaa ccgtgtaggg cttgcccttt ctgtaaaagg ctgttaccac
     5881 tccgattaca tcatcatcgg taataccttt ttcaacggca aactgattgt caccgcacat
     5941 agtataactg ccgtcacttc cgaaattgac gacacggtgc aatacatacg agccgtcttt
     6001 tcgtctgtat aaaggcaagt caaaaagatg aagtctgccc ttcggttttg ataaaacaac
     6061 cgtatcgtca ccgtctcgga gcattgggag catacttgtt cccttcggat tgaaagtaac
     6121 cgatcctccg gtctcaagct tttcggctat aatctgcatt acatcatcaa gacctacttc
     6181 tttattcaag gacatcagcc tctcttagct tttgaataaa tgtatcaata tcggcactcg
     6241 ccttatcttc gctcacttca tactcatcaa gcattgcttt gagcaaatca gccttttcgc
     6301 aatcgttttg gagcttttca aaaaggaatg cacccgtttc attgaggttg ataattccgt
     6361 taaaatcaag cgttagcttg tttacgggaa ctacaacata tgaatctgca accttacgca
     6421 gaacaaaatc ttcttttatc ttcataaaat cacctgtttt ccgtgtgaat ttttcataca
     6481 tatttaaatt ataatatacc tttcgacaaa aagcaagaaa aaggatttga gcataaaatt
     6541 accgcagacc ttttgagtct gcggtaaaaa ttatctataa tattacagct tacgggatta
     6601 gtacattccg cccatatcag gtgctgcggg agctgcagga gctgcaggct ctttgatgtc
     6661 tgtaacaagt gattctgttg taagaaccat tgctgcaaca gagcttgcgt tctggagagc
     6721 tgaacgagta acctttgttg ggtcaacgat acctgccgaa accatatctg tgtattcctc
     6781 tgtaagagcg ttgaagccat agccaacctt gttagccttc ttaacattat cgcagattac
     6841 gctgccctca agacctgcgt tagcaacaat ctgacggagc ggttcttcaa gtgctttaag
     6901 aacaatctta gcacctgtct tggcgtcacc ctcgagagtg tcaacgaact cagcaacagc
     6961 cggaatagcg ttcatgcaag cgataccgcc gcctgctacg ataccctctt caacagcagc
     7021 ctttgtagcg gcaagagcat cctcaatacg gagcttcttt tctttcattt caacttctgt
     7081 tgcagcacca accttgataa ctgctacgcc gcctgcgagc tttgcaagac gctcctgaag
     7141 tttttcacgg tcaaagtcag atgttgttgt ttcaatctgc tgtctgatct gagcaactct
     7201 gcccttgata gcttccttgt cacctgagcc gtcaacgatg attgtgtttt ccttttcaat
     7261 cttaacctga cgggcagtac cgagctgatc aactgttgta tccttgagtt caagaccgag
     7321 gtcggatgtg attaccgtac cgcctgtgag tgttgcgata tcctgaagca tttcttttct
     7381 tctgtcgcca aagcccggag cctttacggc aacacaagtg aatgtacctc tgagtttgtt
     7441 aagtacgaga gttgtaagag cctcgccctc aacatcttcg gcaatgataa ggagcttctt
     7501 acccatctga acaatctgct caagaagtgg gagaatttcc tgtgtagtag aaatcttctt
     7561 atctgtgata aggataagcg gattgtcaag ctctgcaacc atcttatctg tatctgttac
     7621 catataagga gcgatgtaac ctctgtcaaa catcatacct tcaacaacct cgctgtatgt
     7681 ttcggctgtc tttgattcct caactgtgat aacaccgtct gttgtaacct tttccatagc
     7741 ctcggcaata agcttaccga tgaattcatc ctgtgatgaa actgttgcaa ctcttgcgat
     7801 atcatctgta ccggatacct gcttgctgtt cttctttaca gcctcaactg caacatttac
     7861 agcgtctgca ataccctttt taagtaccat tgggttagcg cctgcagtta cattcttcat
     7921 accctctctg atgagagcct gagcaagaag tgtggcagtt gttgtaccgt cgcctgcgat
     7981 atcgttagtc ttgatagaaa cttcctttac aagctgagcg cccatatttt caaaaggatc
     8041 ttcaagttca atttccttag caattgttac accgtcattt gtgatgagcg gagcaccgaa
     8101 cttcttatca agaacaacat ttctgccctt aggtccgagt gtgattttaa cggtatcagc
     8161 gagctggtcg atacctttca ttaaagcttt tcttgcatct tcgccgtatg cgatttgttt
     8221 agccattgta aattacctcc gtatatttag ttaattattc aagagttgcg agtatatccg
     8281 actggtttac aattgtgtat tcttcgccgt caatctttac ctgtgtgcct gcatatttac
     8341 ttgcgataac cttatcgcct acgctgacat acatctttac ttccttgccg tcaacaacac
     8401 cgccggggcc aacagcaaca actgatgcga actgtggctt ttcctgagca gcagatgaaa
     8461 gaatgatacc gctctttgtt ttctcttcag cctcttcaac ttttaaaacg actctgtcga
     8521 gtaatggttt gattgtcata aatacagcct cctgtaaaaa ttttaaattg cttttaatta
     8581 attagcactc ttgttccctg agtgctaatt atattttata ccattttcaa gaaaagtcaa
     8641 gagaaatttg actatttttg acctttattt tgtgacagtt ttctgaaatt ttttccaatc
     8701 tcaattttat cgagtatttt aagataatca gtaactatag ctgttttata tcaataaaaa
     8761 agacggactg caaaaagtcc gtcttaaaca ttgttattaa ttttatctgt ttgatgattg
     8821 agaacttgtc tgtttcttgc ccttgctgac aacaagaact accgttgaac cgtattcgag
     8881 agtatcaccc tcaacatgtt ctttgtagcg gattaccctt ccctcagcaa ccttgtcact
     8941 gtactcatat tctgctgttg caagaagtcc ctgagcggca atgtcagatg caacggtatc
     9001 aagtttttca ccctcaacct tcggcagagt cctcatctgt gatcccttgc ttacgcaaac
     9061 actcactact acggaatctt cctgagtaat ttttgaacct gcggcaggag tctgtgacat
     9121 aatcttacct tctgcataat catcgctgta ctcatcgtta aaagttctgt agattgtgat
     9181 actgctgttg ctgtcaacac tcttaacagc ctcttcatat gtcattccta tatagttagg
     9241 aacagtagca cctgtccact ctgtgctttg agttgagctt acactcgcat cagtattatt
     9301 cgaaaacatt ccggcaagcg gattctgcat aagccagaac acaccggcaa taccgagaac
     9361 aagaaccgtg atagcagccg caataataat aattgaagcg tgtgacatac cgtttgaagt
     9421 cttgcgtgta cgctctgact ttgtgaggtt catgcttgct gttcttgaaa tttcgtcctg
     9481 aattgccttt gctgtatgag caacggaaag ctgtgaacga agctcgtcaa aatccgtaat
     9541 acggttttca cgctcaacct gcaaaccgtt agcaagagcc gaaacaacat gcggaggaag
     9601 tctctttacg gttgttgtgc tcataagaag tcggctgtcc ttacggcgtt ctaccgcact
     9661 ctttggcata tgacccgtga gggcatagaa aagggttgca caaaatccgt agatatccgt
     9721 aatatcgtca agaggaaaat tgtcgtcata ctgttcggga gccgcagcgc ctgaaaaaag
     9781 ctgagatttg agaggcgtgc ctcttttacg ctcattttcc gacgcaaagc ctgaaatctt
     9841 aattttaccc gatgctgtga tatacatatt cttaggtgcg atagcatagt gaccgacacc
     9901 tctcttgtga agagcctcga gtgcagaaat tacaggcata aaaagcggac gggcaatatc
     9961 ccattcaaga tgaccgttac tgcgttcaac atactcctca aaaggaataa gatcctcgtt
    10021 ttcctcaaca acataaactg tgttattttc ttcaaaaatg ttgtgaacat tcataagagc
    10081 ggaaagctca cggagttctg aaagaatcct gtaatagtta agaaaatcgt ccttgagttt
    10141 attatataca aggcggtttt cataatttat tctgacctcg gtagttcctt cttcacgaga
    10201 aaaaagtccg ataggaagaa attcgcagat gattacaatg tcacctgtct gcttgtcgtg
    10261 gcttatatag cgtgtgcttt cgccgttggt atcaattccc gcacctacga tatagcggtt
    10321 ctgaagaatt gttccgtacg gtaaaaaagg agcttgctgt ttttcagttg tatcaaatcc
    10381 gcaggacgga caaatcttgt tgtcacctat ttcctgcatg catcccatac acaatgacat
    10441 attattactc aactccaaat aagtatcaat ttcaaatttt gtctgaaaag aattatacca
    10501 taaaaacata tttcttttca agacttaaag gtgttaatat agttacaatt ttgttattgc
    10561 aaagccttac aaagcaaatt ctttgcaaat attgttgtat aaaaaatgtg gtggagataa
    10621 cggggctcga acccgtgacc ttctgactgc cagtcagaca ctctcccagc tgagctatac
    10681 ccccatataa tgt
//
