LOCUS       gnlProkkaGDFJMIIP_100   9575 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GDFJMIIP_100.
ACCESSION   gnlProkkaGDFJMIIP_100
VERSION     gnlProkkaGDFJMIIP_100
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-18 09:26:48
            Original ID  :: gnl|Prokka|GDFJMIIP_100
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 9575
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..771
                     /locus_tag="ctg100_1"
                     /transl_table=11
                     /translation="MESMQIQSNLGSTIAMAFDECPSSRADRTYIQNSVDRTTRWLERC
                     KKKMQELNSLPDTVNPHQMLFGINQGGVFADIRIEHAKRISELDLDGYAVGGLAVGETH
                     DEMYYILDEVVPYLPENKPTYLMGVGTPANIIEAVDRGIDFFDCVYPSRNGRHGHVYTH
                     HGKLNLFNKKFELDPRPIEEGCQCPACRTYSRAYIRHLLKAKEMLGMRLCVLHNLYFYN
                     HLMEEIRGAIDEHRYKEFKKTTLEGFLTPEEEYR"
     protocluster    1..9575
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[1960:3733]"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1961..3733
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     cand_cluster    1..9575
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..9575
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /tool="antismash"
     CDS             805..1125
                     /locus_tag="ctg100_2"
                     /transl_table=11
                     /translation="MLLAQSASASSSITMIIAYVILFGAIIYFMTIRPQKKQQKAADEM
                     HAGMQAGDSVLTTSGFYGVIIDIMDDTVIVEFGNNRNCRIPMQKDAIAAVEKPNLTKTE
                     EE"
     CDS             1481..1861
                     /locus_tag="ctg100_3"
                     /transl_table=11
                     /translation="MDGISYKKWMERAAGLFLSALIAVLLTMLFLAVFAFAMLKGNLSA
                     SVEKIGLIVMSVMACFVGGFLCGKKNIKKRYLWGLGVGVLYCLFFGVIRVGMGQAFVTD
                     TTAFFTMMLYCAAGGMLGGMLS"
     CDS             1961..2107
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR03973"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SCIFF"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg100_4"
                     /sec_met_domain="TIGR03973 (E-value: 3.8e-23, bitscore:
                     70.6, seeds: 29, tool: rule-based-clusters)"
                     /sec_met_domain="SCIFF (E-value: 1.9e-22, bitscore: 68.4,
                     seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRVKTLTGNKTYGTTMCKGGCGECQTSCQSACKTSCTVGNQTCE
                     SNK"
     CDS             2369..3733
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Ranthipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg100_5"
                     /sec_met_domain="Ranthipeptide_rSAM_RRE (E-value: 1.1e-33,
                     bitscore: 104.9, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 2.5e-16, bitscore: 49.7,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 2.2e-14, bitscore: 43.6,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 1.1e-20, bitscore:
                     63.3, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIHQYKNNGYNIVMDVCSGAIHVVDDVTYDVIALYEEKSLEEIEN
                     ELSYSKEDIEEAYKEVTSLKEEGLLFTEDIYEDYIKEVKSRKTVVKALCLHIAHDCNLA
                     CRYCFAEEGEYKGHRELMSAKVGKAALDFLVANSGNRHNLEVDFFGGEPTMNFGVVKEV
                     VEYGRSLEEKHNKHFRFTLTTNGVLLNDEIMEFANKEMDNVVLSVDGRKEIHDYMRPTR
                     NGKPSYDLIMPKFIRFAESRHQQKYYVRGTFTNRNLDFSKDVLHLADLGFEQISMEPVV
                     GQPEEPYAIQEKDLPQIFDEYDRLAKEMIKREKAGKGFNFFHFMIDLTGGPCVAKRLSG
                     CGSGTEYLAVTPWGDLYPCHQFVGEEKFLLGNVFDGIKRTDICDEFRSCNVYTKKKCKD
                     CFARFYCSGGCPANSYNFHGTIDDSYDLSCDMERKRVECAIMIKAALADTEGEEE"
     CDS             3734..5509
                     /locus_tag="ctg100_6"
                     /transl_table=11
                     /translation="MEKWFIASKRADFNKIGEIFHISPVTARLMRNRSLTTVREMQRYL
                     YGSLSDLYDSHLLKDADKGAEIIKEKIETGKKIRIISDYDVDGVSSNYILYQGLKRCGA
                     DVDYKIPDRVEDGYGINEHLIEKAAEDGIDTIITCDNGIAAAEQIAYGNSLGLTLIVTD
                     HHDIPFQRQEDGSISYNLPSAAAVINPKQKDCPYPFENICGAVVVYKFIQVLYDLFGID
                     RRESEVFLEIAAMATVCDVMPLCDENRIIVKEGLRRIQHTNITGLQALIEANHLEEKKI
                     SSYHFGFILGPCINASGRLTSAKDALELLLCEDKELCRQKAEALTQLNAERKEMTANGV
                     KAAKEYLESTGHANDKVLVVYLPNCHESIAGIIAGRMKEHYHKPVFVITRTKEGLKGSG
                     RSIEAYHMYKEMNKIKECFDKFGGHPMAAGFSMQEDRLEEFREKLNANATLTEDDFAEK
                     VHIDVALPISYLSESLINEFELLEPFGNENTKPLFAQKDLYIKGMRVLGTTGRCLKLFL
                     SDANGTSIDAMYFGESDVFLEELISFCGKEEAQRIQKGLSHHIWMDVTYYPQVNEWRGQ
                     KNIQIVIQNYRFKNL"
     CDS             5680..6525
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1179:hydrolase (Score: 177.9; E-value: 4.8e-54)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg100_7"
                     /transl_table=11
                     /translation="MEQEKKQPDVRLIGLDLDGTTLTSDKVLTPHTKEVLEKCLAEGIQ
                     VLPATGRVKSGIPEYLTQIEGMRYVILSNGASVLDLKEDKVLYQNCIPWERALELFDVL
                     ETYDTFYDIYALGAGWCEARFYDNVENYGIEKHIEKLVRTSRNRIDDLREWMKENKAPV
                     EKINMFFAKEEDRQRAFRELGQIEDLAVTCSLGNNLEINGATCNKGDAMLNLGKILDIP
                     IESIMACGDGNNDFEMVKMAGVGVAMKNGEESLKEVADFVTKTNDEEGVAYAIEHFCNV
                     "
     CDS             6628..7185
                     /locus_tag="ctg100_8"
                     /transl_table=11
                     /translation="MPDLGAERVDKVKKLEDYVINIPDFPKPGIIFRDITSILRDPEGL
                     KLSVHELMHCLEGTEFDVVVGAESRGFLFGMPLAYNKSKGFVPVRKKGKLPRETVSKEY
                     ALEYGTAEIEIHKEDIRPGQRIVFVDDLLATGGTAKAAIDLIEELGGVVVKVLFVMELE
                     GLHGRDVLKGYDVESVITYPGK"
     CDS             7383..8252
                     /locus_tag="ctg100_9"
                     /transl_table=11
                     /translation="MEHLNLLQRIEKKSSEFSKGQRRLAQYITENYDIAAYLTASKLGK
                     EAGVSESTVVRFAYQLDYEGYPELQKAIQVIVKTNSNSIQRMSLSSKRYQEKGVLKSIL
                     YTDSERLRDTIQSGVDEEEFDRSVMLINDARRLYILGARSAAYLAGLMGYYFKMMFDNV
                     IIVDANSTSETLEQIYDISDKDVMMGITFPRYSKRTICALQYAKNHGAKTIALTDNMQS
                     PIVEYADCKLIAKSDVMTIVDSLVCPLSVVNAMVTAIALLRKDDVEKRLMALEELWNEY
                     DVYNRSLL"
     CDS             8252..9493
                     /locus_tag="ctg100_10"
                     /transl_table=11
                     /translation="MNKVIIVGGGAAGMMAAISASKEGKKVCILEKNEKLGKKLFITGK
                     GRCNITNACPADEFLTHVVTNPRFLYSTFSQFNNEDMMDYLEEIGLPIKTERGQRVFPQ
                     SDRSSDVIDALKKQCKKGGVQIYYHTEVKELLFDEEKENCVGVLLSDGKKMIGDSVILA
                     CGGFSYASTGSNGAGYTLAKQAGHKIKSIEPSLVPFEMKETWCKDLMGLTLKNIGVRIK
                     AKKKTVYEGFGEFLFTHFGVSGPLVLTASTCLGKYQKELEAGELKLILDLKASLTPEQL
                     DKRFLREFDTYRNKNISNVMERLLPKKMIPVFLEEAQIPEDKKIRDISKKERRHMIELM
                     KNFEMHITGVRGFNEAIVTRGGVNVKEINPSTMESKKVKHLFFAGEMMDLDAVTGGYNL
                     QIAWTTGYVAGKNA"
ORIGIN
        1 gaagaaagta tgcagattca gtctaatctt ggttctacga ttgcgatggc atttgatgaa
       61 tgtccttcaa gtcgggcaga cagaacctac attcagaatt ctgttgacag aacaacaaga
      121 tggttagaac gctgtaaaaa aaagatgcag gaattaaaca gcctgccaga taccgtaaat
      181 ccacaccaga tgttatttgg tattaatcag ggtggtgttt ttgcggatat ccgtatcgag
      241 cacgctaaaa gaatcagtga gcttgattta gatggttatg cagttggcgg acttgcagta
      301 ggagagacac atgatgagat gtactatatc cttgatgaag ttgttccata tctgccggaa
      361 aataaaccaa cttaccttat gggtgtagga accccagcaa atattattga ggcagttgac
      421 agaggaattg acttctttga ctgtgtatat ccttccagaa atggaagaca cggacatgtg
      481 tatacgcatc atggaaagtt aaatcttttt aataagaagt ttgaattaga cccccgccca
      541 atcgaggaag gatgccagtg tccggcatgt cggacataca gcagagccta tatcagacac
      601 ctgctcaagg caaaagagat gcttggaatg cgtctttgtg ttcttcataa cctgtatttc
      661 tataatcatt taatggaaga aatacgtgga gcaattgatg aacaccgcta caaagagttc
      721 aaaaaaacca cattagaagg ttttttgaca ccggaagaag aataccggta atatattata
      781 tagaagaata acggaggtaa ggacatgtta ttagcacaga gtgcgagcgc aagctcatct
      841 attacaatga tcattgcata tgtcattctt tttggagcga ttatctactt tatgacaatc
      901 cgtccacaga agaagcagca gaaagcagca gacgagatgc atgcaggaat gcaggctgga
      961 gacagcgtat tgactacaag cggattctat ggcgtaatca tcgacatcat ggatgacact
     1021 gtaatcgtag aatttggtaa caaccgtaac tgcagaatcc caatgcagaa agatgctatt
     1081 gcagcagtgg agaagccaaa tcttacaaag acagaagaag agtaatttcg tttgagataa
     1141 cagacgaaaa atgaaaaagc agatatccta tatttgtgat tctattgctg agggttggat
     1201 gttcacctcc gggtttacat tcaatcctcg ctaaggccac aaatatagga tatctgtttt
     1261 ttgctaaatt gaaagtactc tccagtttaa caaagacaga aattaagaga ccgccaatat
     1321 ataaaaaatg cgccttagag caagctctta atgcggacga gcattaagag cgcagtgata
     1381 cgaagcattt tttatatatt ggcggtctct taatttcgtc tctcctgttc taaacagaga
     1441 acccttttca taggctataa aaaagccttt ggtgcagcct atggatggaa tttcgtataa
     1501 aaaatggatg gagcgtgcag caggcctgtt tctttctgca ttaattgcag tattactcac
     1561 aatgctattt ttagcagtgt ttgcatttgc catgttgaaa ggtaatcttt ccgcttccgt
     1621 agaaaaaatt ggtttaattg ttatgagtgt gatggcttgt tttgtcgggg gatttttgtg
     1681 tgggaaaaag aatataaaaa aacggtattt atgggggctt ggcgtaggtg ttttatattg
     1741 cttgtttttt ggagtaatac gtgtcgggat ggggcaggca tttgtgacag atacaacagc
     1801 attttttaca atgatgctgt attgtgcggc aggaggaatg cttggaggaa tgttaagcta
     1861 aaaagttctt ttcttacggg agggtttgtg ttataataat ctataaagtg tcatcttaga
     1921 tgctttacat actagatcat gaagtgagga ggcgttatta atgaaacgtg taaagacact
     1981 gaccggaaac aaaacttacg gtactacaat gtgtaaaggt ggatgcggcg agtgccagac
     2041 atcctgccag tctgcctgca agacatcttg tacagtaggt aaccagactt gcgagagtaa
     2101 taaataatta gagagcacaa caggaagaat gcttcctgat atatgcttga agtagggtgg
     2161 actgtctttt ttgtcagttc accttatctc ttgtatggaa aagtatgttt gcagagatta
     2221 ctttattgta agttgaaaat attgtataca ggaatgttct gtattatata tctattttaa
     2281 agttagcagg acatatcttc aaattaaaaa tatattttag aaaattaagt ataaaaaact
     2341 ataaaagaaa tagaaaggga tatttaacgt gattcaccag tataaaaata atggatataa
     2401 tattgtcatg gatgtgtgca gtggtgccat tcatgttgtt gatgatgtaa cttatgatgt
     2461 cattgcttta tatgaagaaa aaagcttaga agaaatagaa aatgaacttt cttacagcaa
     2521 ggaagatatt gaggaagcat ataaagaggt aacttcttta aaagaagagg gacttttatt
     2581 tacagaagat atttacgaag attatattaa agaggtaaag agcagaaaga cagtagtaaa
     2641 ggcactttgc ctgcatattg cgcatgattg taatcttgcc tgccgctatt gttttgcaga
     2701 agaaggagag tataaaggac accgtgaact tatgagtgca aaggttggaa aggctgccct
     2761 tgatttcctt gtagccaatt ctggaaaccg tcataatctt gaagttgact tctttggcgg
     2821 tgagccaaca atgaacttcg gtgttgtaaa ggaagttgta gaatatggac gttctcttga
     2881 agaaaaacat aacaaacatt tccgtttcac tttgacaacc aatggtgtgc tgttaaatga
     2941 cgagattatg gaatttgcca ataaagaaat ggacaacgtt gttttaagtg tcgatggacg
     3001 taaagaaatc catgattaca tgcgtcctac aagaaatggt aagccaagct atgaccttat
     3061 catgccgaag tttatccgtt ttgcagagtc cagacatcag cagaaatact atgtaagagg
     3121 aacatttacc aatagaaatc ttgatttttc caaagatgtt cttcatcttg cagacttagg
     3181 atttgaacag atttccatgg aaccagttgt tggacagcca gaagagccgt acgcaattca
     3241 ggaaaaagac cttccacaga tttttgatga gtatgacaga cttgcaaaag aaatgattaa
     3301 gagagaaaaa gcaggaaaag gctttaattt cttccacttt atgattgacc ttacaggtgg
     3361 tccatgtgta gcaaaaagac tttccggctg tggaagcgga acagagtatt tagcagtaac
     3421 accatgggga gatttatatc cttgtcacca gtttgtagga gaagagaaat tccttcttgg
     3481 taacgttttt gatggaatca agcgtaccga tatttgtgac gaattccgtt cctgcaacgt
     3541 atacacaaag aaaaaatgta aagactgttt tgcgagattc tactgtagcg gcggctgtcc
     3601 tgcaaactct tataatttcc atggaacaat tgatgattct tatgatttaa gttgcgatat
     3661 ggagcgtaag agagtagaat gcgcaattat gattaaggct gcattagcag atacagaagg
     3721 cgaagaagaa tagatggaaa agtggtttat cgcttcaaaa agagcagatt ttaataaaat
     3781 tggtgagata tttcatatca gcccggtaac ggcgcgtctg atgagaaata ggagcttaac
     3841 aacagttagg gaaatgcagc gttatcttta tggttctctg tctgatttat atgattctca
     3901 tcttttgaaa gatgccgata agggagcgga aatcataaaa gagaagatag aaacaggcaa
     3961 aaagattcgg attatttcgg attatgatgt agatggtgtt tcatcaaact atattttata
     4021 tcagggatta aaacgctgtg gtgcggatgt tgattataag attcctgacc gtgtggaaga
     4081 cggttatgga attaatgaac atctgataga aaaggcagca gaggacggaa ttgatacgat
     4141 tatcacctgt gacaatggaa ttgcggcagc agaacagatt gcttatggaa attctttagg
     4201 actcaccctg attgtgacag atcatcatga tattccgttt caaaggcaag aagatggaag
     4261 catttcttat aatttgccgt cagccgctgc cgttattaat ccgaagcaaa aagattgtcc
     4321 gtatccattt gaaaatatat gcggagcggt tgttgtctac aagtttattc aggtgcttta
     4381 tgatttgttt ggaattgacc gtagagaaag tgaagtattt cttgagattg cggcgatggc
     4441 aacagtctgt gacgttatgc cattgtgtga tgagaaccgt attatcgtaa aggaaggcct
     4501 gcgacggata cagcatacga atattaccgg gctgcaagct ttaattgagg caaatcatct
     4561 tgaagaaaaa aagatatctt cttatcactt tggatttatt ctcggtccgt gtattaatgc
     4621 ttccggtcgt ttgacctctg caaaagatgc gttagaactt cttctatgcg aagataaaga
     4681 actttgcagg cagaaagcag aagcactcac acagctaaat gcagagcgaa aagaaatgac
     4741 agctaacggg gtaaaagctg caaaagaata tctcgaaagc acgggacatg caaacgataa
     4801 ggtacttgtt gtatatcttc caaactgtca cgaaagtatc gccggaatta ttgccggaag
     4861 aatgaaagaa cattaccata agccagtatt tgtcatcaca agaacaaaag aaggattaaa
     4921 aggctctggc cgttctatcg aagcctatca tatgtataag gaaatgaaca aaatcaagga
     4981 atgtttcgat aaattcggtg ggcacccgat ggcagcagga ttttctatgc aggaagaccg
     5041 cttagaagaa ttccgggaaa aattaaatgc caacgcaacc cttaccgaag atgatttcgc
     5101 agaaaaagtt cacattgatg tagccttgcc gatatcttat ttatccgaaa gtctcatcaa
     5161 tgaatttgaa ttactagaac catttggaaa tgaaaacaca aaaccgctct ttgcacaaaa
     5221 agacctttac ataaaaggaa tgcgggtact cggaacaaca ggcagatgtt taaaactctt
     5281 cctgtcggat gccaatggaa caagcataga tgccatgtat tttggagaat ccgatgtatt
     5341 tttagaagaa ctcatctctt tttgtggaaa agaagaggca cagagaattc aaaaaggcct
     5401 gtcacatcat atatggatgg atgtgactta ttatccacag gtaaatgaat ggcgagggca
     5461 gaagaatatc caaatcgtca tccagaatta tcgttttaaa aatttatgag ataaattttt
     5521 tagtgcttct ttcgcatatt ttttcgtctg tttagattcc caattaataa aaaactatcc
     5581 taatttgaca aataaggcga gaatcaatag aataatatga ggatgaaaag agagatacat
     5641 caaaatcgct atgaattaag agatagataa ggagaaaata tggaacagga gaaaaaacag
     5701 ccagatgtca gattgatagg attagattta gatggaacaa cgctcacttc agataaggtg
     5761 ttaactccac atacaaagga agtacttgag aaatgtcttg cggaagggat tcaggtttta
     5821 ccggcaacag gaagagtaaa atcgggtatt ccagagtatt taacacagat tgaaggaatg
     5881 agatatgtta ttttatccaa tggtgcaagt gtattagatt taaaagagga taaagttctt
     5941 tatcagaatt gtattccgtg ggagagagca ttggagttat tcgatgtgtt agaaacatat
     6001 gatacatttt atgatattta tgcattagga gctggctggt gtgaggctcg cttttatgat
     6061 aatgtagaaa actatggaat tgagaaacat atcgagaagc tggttcgtac atcacgcaat
     6121 cgtattgatg atttaagaga gtggatgaaa gaaaataaag ctccagtgga gaagataaat
     6181 atgttctttg caaaggaaga agacagacag agagctttcc gtgaacttgg acagatagaa
     6241 gatttggcgg ttacctgttc tcttggtaat aatcttgaga ttaatggggc aacttgtaat
     6301 aaaggagatg cgatgctcaa tcttggaaaa attcttgata ttccgataga aagtattatg
     6361 gcgtgcggcg atggcaataa cgattttgag atggttaaga tggctggtgt cggtgttgct
     6421 atgaaaaacg gagaagagtc tttgaaagag gttgcagatt ttgtgacaaa gacaaatgat
     6481 gaggagggcg tagcatacgc tatcgagcat ttttgtaatg tgtaagtaga aataaacgtt
     6541 tttctgttgt tttttacata aaaaatctgt tataattaat cataagaaga aaaagcgcga
     6601 agataaaagt ctgtgcttaa tagttttatg cctgatttgg gggcagaaag ggtggacaaa
     6661 gtgaaaaaac ttgaagatta tgtcattaat attccagatt tcccaaagcc gggaattatt
     6721 ttcagagata ttacctctat tttacgtgat ccggagggac tgaaacttag cgtacatgaa
     6781 ttaatgcatt gcttagaggg aacagagttt gacgtagttg ttggagcgga atcccgtgga
     6841 tttttatttg gtatgcctct tgcttacaat aaaagcaagg gatttgttcc tgtccgtaag
     6901 aaaggaaagc tgccaagaga gactgtaagc aaagaatatg ctttagagta tggaacagca
     6961 gagattgaaa tccataaaga ggacattcgt ccaggacaaa gaatcgtatt tgtagatgac
     7021 cttttagcaa ctggtggaac agcaaaggct gcgattgatc tgatcgaaga acttggtggc
     7081 gttgtcgtaa aggttctgtt tgttatggaa cttgagggat tgcatggccg tgatgtatta
     7141 aaaggctatg atgtagagtc tgttattact tatcctggaa agtaattttg aaggaaaaga
     7201 aactgtgtgg atggaatttt tcggaaacac agtttttctt tgtgtaaaaa ttgttctgta
     7261 gttataaatt tgaattttca tttgcaattt ctttctttaa atcctgcatt ttgctttaca
     7321 aaaagaagaa aatggagtat tatgaaatat acttaatttt acagaatagg tggaagaata
     7381 gagtggaaca tttaaattta ttacagagaa tagagaagaa gtcttccgag ttcagtaaag
     7441 gacagagaag actggctcag tatattacag agaactatga tattgcggca tatcttaccg
     7501 cttcaaagct tggaaaggaa gcaggagtca gtgagtctac agtggttcgt tttgcttatc
     7561 agcttgatta cgagggatat ccagagctgc agaaggcaat tcaggttatt gtaaagacaa
     7621 actcaaactc cattcagaga atgtcccttt cctcaaaaag atatcaggaa aaaggtgtat
     7681 taaagagtat tttgtataca gattcagagc ggcttcgcga tacgattcag agcggtgtag
     7741 atgaggaaga atttgacaga tccgttatgc ttatcaatga tgcaagaaga ttatatattt
     7801 taggtgcgag aagtgcggct tatcttgccg gtctgatggg atattatttt aagatgatgt
     7861 ttgacaatgt aattatcgta gatgccaaca gcacgtccga gacattagag cagatttacg
     7921 atatcagtga taaggatgtt atgatgggaa ttacttttcc aagatattca aagagaacca
     7981 tctgtgcgct tcagtatgcg aagaatcatg gagcgaagac aatcgcactt accgacaata
     8041 tgcagtctcc aattgtagag tatgcagatt gtaaattgat tgcaaagagt gatgtaatga
     8101 caatcgtgga ttctttagta tgtccgttaa gtgtggtgaa tgcgatggtt acagcgattg
     8161 cattgcttcg taaggatgat gtagagaagc gtcttatggc acttgaagaa ctctggaacg
     8221 agtatgatgt ttataacagg agtttactat aatgaacaaa gtaattattg taggcggagg
     8281 ggcagccggt atgatggctg ccatttctgc gtctaaagag gggaaaaagg tctgcattct
     8341 tgaaaagaac gaaaaacttg gcaagaagct ttttattacg gggaaaggca gatgcaatat
     8401 tacaaatgcc tgtccggcag acgaatttct tactcatgtg gtaacaaatc caagattttt
     8461 atacagtaca ttttctcagt ttaataatga ggatatgatg gactatttag aagaaattgg
     8521 tcttccgata aagacagaga gaggacagag agtatttcca cagtccgacc ggtcttcgga
     8581 tgtaattgat gcattaaaga aacagtgtaa aaaaggcggg gtacagattt actatcacac
     8641 agaagtaaaa gaactgcttt ttgatgaaga aaaagaaaac tgtgtcggtg tacttttgtc
     8701 tgacggaaag aaaatgatag gagattctgt tatccttgcc tgcggcggct tttcctacgc
     8761 ttctaccggt tccaatggag caggatatac acttgcaaag caggcaggac ataagattaa
     8821 gtctatagag ccatctttag ttccatttga gatgaaagaa acgtggtgca aagatttgat
     8881 gggacttact ttaaagaata taggggtgcg tatcaaagca aagaaaaaga cagtttatga
     8941 ggggtttgga gaatttctct ttacgcattt tggagtgagt ggtccgcttg ttcttacagc
     9001 aagtacctgt cttggaaaat atcagaaaga gttagaggca ggcgaattaa aactgattct
     9061 tgatttaaaa gcctctctta ccccggaaca gttagataaa cggtttttaa gagaatttga
     9121 cacttatcgt aataaaaata tttctaatgt gatggaacgt cttcttccaa agaaaatgat
     9181 tcctgttttt ttagaagaag cacagattcc ggaagataaa aagataagag acatcagcaa
     9241 aaaagaaaga aggcatatga ttgagctgat gaagaatttc gagatgcata tcacaggagt
     9301 ccgtggcttt aatgaggcaa tcgtcacgag aggcggagta aatgtaaaag aaattaatcc
     9361 gtctacaatg gagtctaaaa aagtaaaaca tttatttttt gccggagaaa tgatggattt
     9421 agatgctgtc acaggcggct ataacctgca gattgcatgg acaacaggct acgtagcagg
     9481 taaaaatgcg taaagaaaac gtaaaattta aaaaattata aaaaaatagt tttttttttc
     9541 ggaaaaatat gttacactaa tcaagtgtag gtaaa
//
