LOCUS       gnlProkkaEOMAMBIB_74   14405 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|EOMAMBIB_74.
ACCESSION   gnlProkkaEOMAMBIB_74
VERSION     gnlProkkaEOMAMBIB_74
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-18 10:38:33
            Original ID  :: gnl|Prokka|EOMAMBIB_74
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14405
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14405
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[3963:12948]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3964..12948
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..14405
                     /SMILES="NC([*])C(=O)NC([*])C(=O)NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..14405
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /tool="antismash"
     CDS             complement(117..338)
                     /locus_tag="ctg74_1"
                     /transl_table=11
                     /translation="MIRSQPRTCLKNAFRKMYVTIYGRFCSDESVVTASYGNRIRAKYT
                     AKWGMQIVGMIFQTHSGSVLDLIECSLI"
     CDS             392..1189
                     /locus_tag="ctg74_2"
                     /transl_table=11
                     /translation="MQGLRNMLLQEQKHLQEIADKARMGMSVEPEGHLRISRDKNKPRY
                     YQCIDGNNEIYIPRSNKELPKLLAQSTYNRTVLKKVETRLKQIKKILQDYTDDEIERIY
                     TSMHKERQLLVTPIEPTWNQLLMKWYEEEYQGKEFKEGIPVILTEKGERVRSKSEKIIA
                     DYLYRKNILYKYEKPLYLNGYGIVYPDFTLLSRKTGKEIYWEHEGMMDDQEYARKAIQK
                     IESYQMNDIYQADRLILTFETKQCVLNSKIIENLTARYLFEMI"
     CDS             2205..3950
                     /gene_functions="transport (smcogs) SMCOG1086:MATE efflux
                     family protein (Score: 265.4; E-value: 1.4e-80)"
                     /gene_kind="transport"
                     /locus_tag="ctg74_3"
                     /transl_table=11
                     /translation="MEERNNRLLNAKLNKYIVPGIMMSLALQLGNIVDTIFVSNLIGVE
                     AMSAVTLSLPVETLVQLTGYCLGIGGSIAVGNMLGKRDKEGASKLFSATFIVTLVVGII
                     FSICALPAAEPVARLLVSGDGVLTGYTRDYIRVSMLGAPVIGIGLMMVNYLGVENHPEL
                     ASAYLIAANVINLVLDYIFLRYTPLGITGASLSTVLGFLFAMGIFVLYIRSDKRNLHLI
                     LLKPGELGITKEAIITGVPMLIFMAANFVKALGLNTIIMNQLGEEGMAVFTVCDNVLLI
                     VEMLTGGIIGVIPNVAGILFGEKDYVGIRVLCKKMLKYSYILLAVIFVLIMLFTEEITV
                     MFGSGGGELGSHMVQALRIFALCVAPYLWNKFIISYYESIEETAIASFATFLENAVVVL
                     PATLVGILVWKQIDGIGIDGIAAGFVATEIITAVAACIFRKIRHKNTSFYIVPDKNPGI
                     NLDFSIKSTMEEAQTVHKRIIEFCQEQGASKSKANLAAVCAEEMTVNIIRFGGKTSNWI
                     DINLCLEDELCRLRIRDNGVNFNPLEYQYDSEDFDIHGIELVKKVSKSMDYIRAIDMNN
                     TIISF"
     CDS             3964..12948
                     /NRPS_PKS="Domain: AMP-binding (20-419). E-value: 1.1e-104.
                     Score: 342.1. Matches aSDomain:
                     nrpspksdomains_ctg74_4_AMP-binding.1"
                     /NRPS_PKS="Domain: PP-binding (521-585). E-value: 1.3e-11.
                     Score: 36.8. Matches aSDomain:
                     nrpspksdomains_ctg74_4_PP-binding.1"
                     /NRPS_PKS="Domain: Condensation_LCL (597-878). E-value:
                     1.2e-37. Score: 121.4. Matches aSDomain:
                     nrpspksdomains_ctg74_4_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (1033-1421). E-value:
                     2.7e-91. Score: 298.0. Matches aSDomain:
                     nrpspksdomains_ctg74_4_AMP-binding.2"
                     /NRPS_PKS="Domain: PP-binding (1530-1591). E-value:
                     1.7e-09. Score: 30.0. Matches aSDomain:
                     nrpspksdomains_ctg74_4_PP-binding.2"
                     /NRPS_PKS="Domain: Condensation_LCL (1603-1879). E-value:
                     2.7e-38. Score: 123.6. Matches aSDomain:
                     nrpspksdomains_ctg74_4_Condensation_LCL.2"
                     /NRPS_PKS="Domain: AMP-binding (2027-2418). E-value: 2e-94.
                     Score: 308.4. Matches aSDomain:
                     nrpspksdomains_ctg74_4_AMP-binding.3"
                     /NRPS_PKS="Domain: PCP (2523-2590). E-value: 6.8e-21.
                     Score: 66.2. Matches aSDomain:
                     nrpspksdomains_ctg74_4_PCP.1"
                     /NRPS_PKS="Domain: NAD_binding_4 (2634-2872). E-value:
                     1.4e-35. Score: 114.5. Matches aSDomain:
                     nrpspksdomains_ctg74_4_NAD_binding_4.1"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     143.3; E-value: 2.1e-43)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg74_4"
                     /sec_met_domain="AMP-binding (E-value: 1.1e-108, bitscore:
                     352.2, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.6e-12, bitscore:
                     36.8, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 5.3e-49, bitscore:
                     155.7, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 1.3e-08,
                     bitscore: 23.1, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="RmlD_sub_bind (E-value: 2.4e-14, bitscore:
                     41.9, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 1.7e-36, bitscore:
                     114.5, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNINERNNFVFEFRPVTELFEEQVKLHPEKCAVVSGKESFTYAQ
                     LNERANRIANALVEKGVRRETIVGVVLERCCDFYAVRQGILKAGGAFAVATPDYPDDRI
                     RYIFEDSGAPFIITTKEIAEERRELFAKLPCTVLLIEELLENENAENPQVKIGEHDLCY
                     CIYTSGSTGKPKGVLIEHINLANFVNPDPKNAETYGYVSRGSVSLSMAAMTFDVSVLEE
                     FLPLTNGMTAVIASDEEILNPLMLGELIVRNKVDIMTTTPTYLSNMIDLPQLEKAVSQI
                     KVFDVGAEAFPPALYDKIRRVNPDAYIMNGYGPTETTISCTMKVITDSRNITIGTPNGN
                     VKVYIVDKENKILPDGETGELVIAGLGVGRGYMNLPDKTEAVFIDLNGERAYKTGDLAR
                     ISPEGEIEFFGRIDNQIKLRGLRIELGEIEEVINSYEGIITSITLPVDNKFLCCYFMAD
                     RQINTEELSAYASESLAHYMVPEVFVQLEKMPVTQNGKIDKKALPKPAAQPKNLKEPQT
                     PMQKKIFEIVADVVENDFFGTDTSFYRAGLSSISAMKLCILISEEFGVTVKTSDIHENN
                     TVEKLEKYVMLAPKIRTYEKREVYPLTGSQKGIFAECMKNPESTVYNIPFLFELESSVD
                     VQKLSDAISQMIAAHPYLLTKVYLSDSGEMVQKPCEEAFVPEVVRTTNEQFEKIKDELV
                     RPFKLEKGRLFRAGIYVTEDRKYLFTDFHHILADGNSYDIIFEDIDRAYLGEKLEKESY
                     TGFDAALDEEQQMKEGKYKKAEKYYDSIFEGIETESLPLPDCSGKTPERGYLSMPVDTG
                     ESLVLSACEKLGVTPNILFTGVFGILMSRYSNSEESLFATIYNGRNDSRLENTVCMLVK
                     TLPVYCSCDPKVTIQAYMTELSEQILSSMANDIFPFSDICAKYGINSDLVFAYQAELGD
                     DFPIGDTVARGHDLSPDMSKMPLLIQVREYDHKYVLTAEYRSDMYSEAFVRGMLESYEA
                     AMDSLLKAKYISEVSVLSQNGADKIAEFNNTACEYDRSKTIADMFEELVQTIPDHTAVV
                     FKDKKYTYRELDEISDRLGKYIASQGIGSEDVVSILIPRCEYMAIAPMGVIKAGAAYQP
                     LDPTYPRDRLMYMMEDSSAKLLIADRELLPLVDGYKGPVLFTDQIWQMEDRDVVLKKPQ
                     LHDLFILLYTSGSTGVPKGCMLEYGNITAFCHWFKRYYGIDSDSRVAAYASFGFDACMM
                     DIYGAITNGAQLHIIPEEIRLDFIGLQRYFEENGITHSFMTTQVGRQFALEMDCKSLRY
                     LSVGGEKLVPCEPPKDYKFINAYGPTEATIFTTVFEVDKYYPNVPIGKALDNVKLYITD
                     KLGHMLPPGACGELMITGWQVSRGYLNKPEKTAEVYTKNLYDDTPGYEVMYHSGDVARF
                     LPDGNIQIIGRKDSQVKIRGFRIELSEVEEVIRRYEGIRDATVVAFDDPNGGKYIAAYV
                     VSDSTVDINALNDFIKETKPAYMVPAVTMQIDKIPLNQNQKVNKKALPLPEKKAAEIIK
                     PENEVQQILFDCIAEVLGYTDFGITTDIYKAGLTSITAIKLNILISKAFDIVIKTSDIK
                     NHPTIRMMEEFVKTAGKESKREVQESYPLTNTQEGIFIECTANMGSTIYNIPYLLKLDN
                     KVDLDRLAEAIDSTVEAHPYLKTRLFMDDNGNVLQKRNDGLSYKTPILNGMNRDTLVRP
                     YMLFNEQLFRFEIYRTCDGNYLFLDLHHIVADGTSLAIIINDINRAYSGEKLEPEGYTS
                     YDLALDNRDALAGDIYKNAENYYKSVFEHAGGSISFYPDKNGAAPTAELYHRETRSISV
                     QNVKEFCKKHGITENVFFISAFGITLGKYNFKKDAVFTTIYHGRNDSRLSETVGMLVKT
                     LPVFCDFSGTAKDCLSGVQKQLIDSMNNDIYPFSQISHEFDIKADAMVIYQGDNFAFDT
                     IGGEYAQEEPVSLNMAKAPVSVSISIEKNRFVFEIEYRGDMYHEETIRYLADNLETTAE
                     GILRECDPADIRLMFEEKTQMEDIPEHAGKTFIDLFKEMAARYPDRPAVRDDSGDFTYR
                     ELDRMSDYIAQKLTENGFGPEQAAGILCGRTKEYTVAYVGVMKAGGAYVPLDPEYPQSR
                     IEYMLKDSGARNLLVIDQYQNLVEFYDGNVISLDSVSDEAEDFELSAELISPKPENLAY
                     MIYTSGSTGKPKGVMIEHRNLLNLIEYITLSRNTSPDDIVAEFASFCFDASVIDLFAPL
                     TAGAVLYILPESIRKDAIAISRYIKEKEITTVTFPTQMGELVAELLEDAPALKFVTLGG
                     EKFKHYRNRTYQMINGYGPTENTVSSTEFLVDRQYDNIPIGKSQRNVRSYIVDENLNRL
                     PVGASGELCHAGRQIARGYHNLPEKTASVFVENPFAVCEQESRLYRTGDMVRMKGDGNI
                     EYIGRIDSQVKIRGYRVELGEIEGALLKHELVKNAAVTVIEKGGNKYITAYYTGEAIPE
                     DELKTFLEPLIPDYMMPSFFVSIEEMPVTPGGKIDKKALPMPEVTTNTASYVEPVTAAQ
                     RALCEIFEKALGIERVGIEDNFFELGGSSLTASKVAVMCLSKNISLVYADIFKYPTVRE
                     LAALVDDDGVTEAAQSKNEFSDYNYNRIQNVISANTEENADRITKEKLGDIMVTGATGF
                     LGIHVLKAFLDNYDGKVYCLVRKGKYESPEKRMMNMLMYYFDDPYKELFESRIICVDGD
                     ITSKEQVTGFSEYKFSTIINCAACVKHFAADDVLERINVQGVENLIDFCKNNGRRLIQI
                     STVSVAGEGSDGVPPMSRVFCENDLYIGQNITNEYIRTKFLAERAVLEAVSEGLDGKVV
                     RVGNLMSRNSDGEFQINFITNGFLRSLRGYAAVGKFPMGGMHEVAEFSPIDSTALAVLR
                     LAQTDRRFTVFHACNSHHIYMADLIYAMRSYGFRIDIVRDEEFEAAVKEFAKTGQDSDA
                     VSGLIAYTSHNENEIYTIDYSNRFTAQVLYRLDYKWPVTDDRYLENAIAALDRLTFFD"
     aSDomain        4024..5220
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg74_4_AMP-binding.1"
                     /evalue="1.10E-104"
                     /label="ctg74_4_AMP-binding.1"
                     /locus_tag="ctg74_4"
                     /protein_end="419"
                     /protein_start="20"
                     /score="342.1"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FEEQVKLHPEKCAVVSGKESFTYAQLNERANRIANALVEKGVRRE
                     TIVGVVLERCCDFYAVRQGILKAGGAFAVATPDYPDDRIRYIFEDSGAPFIITTKEIAE
                     ERRELFAKLPCTVLLIEELLENENAENPQVKIGEHDLCYCIYTSGSTGKPKGVLIEHIN
                     LANFVNPDPKNAETYGYVSRGSVSLSMAAMTFDVSVLEEFLPLTNGMTAVIASDEEILN
                     PLMLGELIVRNKVDIMTTTPTYLSNMIDLPQLEKAVSQIKVFDVGAEAFPPALYDKIRR
                     VNPDAYIMNGYGPTETTISCTMKVITDSRNITIGTPNGNVKVYIVDKENKILPDGETGE
                     LVIAGLGVGRGYMNLPDKTEAVFIDLNGERAYKTGDLARISPEGEIEFFGRIDNQIKLR
                     "
     aSModule        4024..5718
                     /complete
                     /domains="nrpspksdomains_ctg74_4_AMP-binding.1"
                     /domains="nrpspksdomains_ctg74_4_PP-binding.1"
                     /locus_tags="ctg74_4"
                     /monomer_pairings="X -> X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       4213..4239
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg74_4_0001"
                     /evalue="8.30E-01"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg74_4"
                     /protein_end="92"
                     /protein_start="83"
                     /score="3.9"
                     /tool="antismash"
                     /translation="GILKAGGAF"
     CDS_motif       4447..4506
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg74_4_0002"
                     /evalue="1.70E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg74_4"
                     /protein_end="181"
                     /protein_start="161"
                     /score="29.7"
                     /tool="antismash"
                     /translation="CYCIYTSGSTGKPKGVLIEH"
     CDS_motif       4897..4926
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg74_4_0003"
                     /evalue="3.10E-02"
                     /label="NRPS-A_a5"
                     /locus_tag="ctg74_4"
                     /protein_end="321"
                     /protein_start="311"
                     /score="7.4"
                     /tool="antismash"
                     /translation="YGPTETTISC"
     CDS_motif       5023..5112
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg74_4_0004"
                     /evalue="2.90E-11"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg74_4"
                     /protein_end="383"
                     /protein_start="353"
                     /score="35.6"
                     /tool="antismash"
                     /translation="PDGETGELVIAGLGVGRGYMNLPDKTEAVF"
     CDS_motif       5185..5250
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg74_4_0005"
                     /evalue="5.90E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg74_4"
                     /protein_end="429"
                     /protein_start="407"
                     /score="31.3"
                     /tool="antismash"
                     /translation="FFGRIDNQIKLRGLRIELGEIE"
     aSDomain        5527..5718
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg74_4_PP-binding.1"
                     /evalue="1.30E-11"
                     /label="ctg74_4_PP-binding.1"
                     /locus_tag="ctg74_4"
                     /protein_end="585"
                     /protein_start="521"
                     /score="36.8"
                     /tool="antismash"
                     /translation="KIFEIVADVVENDFFGTDTSFYRAGLSSISAMKLCILISEEFGVT
                     VKTSDIHENNTVEKLEKYV"
     aSDomain        5755..6597
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg74_4_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="1.20E-37"
                     /label="ctg74_4_Condensation_LCL.1"
                     /locus_tag="ctg74_4"
                     /protein_end="878"
                     /protein_start="597"
                     /score="121.4"
                     /tool="antismash"
                     /translation="EVYPLTGSQKGIFAECMKNPESTVYNIPFLFELESSVDVQKLSDA
                     ISQMIAAHPYLLTKVYLSDSGEMVQKPCEEAFVPEVVRTTNEQFEKIKDELVRPFKLEK
                     GRLFRAGIYVTEDRKYLFTDFHHILADGNSYDIIFEDIDRAYLGEKLEKESYTGFDAAL
                     DEEQQMKEGKYKKAEKYYDSIFEGIETESLPLPDCSGKTPERGYLSMPVDTGESLVLSA
                     CEKLGVTPNILFTGVFGILMSRYSNSEESLFATIYNGRNDSRLENTVCMLVKTLPVYCS
                     "
     aSModule        5755..8736
                     /complete
                     /domains="nrpspksdomains_ctg74_4_Condensation_LCL.1"
                     /domains="nrpspksdomains_ctg74_4_AMP-binding.2"
                     /domains="nrpspksdomains_ctg74_4_PP-binding.2"
                     /locus_tags="ctg74_4"
                     /monomer_pairings="X -> X"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       5821..5916
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg74_4_0006"
                     /evalue="9.10E-06"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg74_4"
                     /protein_end="651"
                     /protein_start="619"
                     /score="18.1"
                     /tool="antismash"
                     /translation="TVYNIPFLFELESSVDVQKLSDAISQMIAAHP"
     CDS_motif       6127..6192
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg74_4_0007"
                     /evalue="3.10E-04"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg74_4"
                     /protein_end="743"
                     /protein_start="721"
                     /score="13.5"
                     /tool="antismash"
                     /translation="FHHILADGNSYDIIFEDIDRAY"
     CDS_motif       6529..6588
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg74_4_0008"
                     /evalue="5.10E-01"
                     /label="C5_starter_265-294"
                     /locus_tag="ctg74_4"
                     /protein_end="875"
                     /protein_start="855"
                     /score="3.1"
                     /tool="antismash"
                     /translation="GRNDSRLENTVCMLVKTLPV"
     aSDomain        7063..8226
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg74_4_AMP-binding.2"
                     /evalue="2.70E-91"
                     /label="ctg74_4_AMP-binding.2"
                     /locus_tag="ctg74_4"
                     /protein_end="1421"
                     /protein_start="1033"
                     /score="298.0"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FEELVQTIPDHTAVVFKDKKYTYRELDEISDRLGKYIASQGIGSE
                     DVVSILIPRCEYMAIAPMGVIKAGAAYQPLDPTYPRDRLMYMMEDSSAKLLIADRELLP
                     LVDGYKGPVLFTDQIWQMEDRDVVLKKPQLHDLFILLYTSGSTGVPKGCMLEYGNITAF
                     CHWFKRYYGIDSDSRVAAYASFGFDACMMDIYGAITNGAQLHIIPEEIRLDFIGLQRYF
                     EENGITHSFMTTQVGRQFALEMDCKSLRYLSVGGEKLVPCEPPKDYKFINAYGPTEATI
                     FTTVFEVDKYYPNVPIGKALDNVKLYITDKLGHMLPPGACGELMITGWQVSRGYLNKPE
                     KTAEVYTKNLYDDTPGYEVMYHSGDVARFLPDGNIQIIGRKDSQVKIR"
     CDS_motif       7249..7290
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg74_4_0009"
                     /evalue="5.90E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg74_4"
                     /protein_end="1109"
                     /protein_start="1095"
                     /score="13.3"
                     /tool="antismash"
                     /translation="MGVIKAGAAYQPLD"
     CDS_motif       7480..7530
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg74_4_0010"
                     /evalue="1.40E-06"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg74_4"
                     /protein_end="1189"
                     /protein_start="1172"
                     /score="20.8"
                     /tool="antismash"
                     /translation="LLYTSGSTGVPKGCMLE"
     CDS_motif       7882..7908
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg74_4_0011"
                     /evalue="8.40E-02"
                     /label="NRPS-A_a5"
                     /locus_tag="ctg74_4"
                     /protein_end="1315"
                     /protein_start="1306"
                     /score="6.2"
                     /tool="antismash"
                     /translation="YGPTEATIF"
     CDS_motif       8011..8097
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg74_4_0012"
                     /evalue="2.10E-12"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg74_4"
                     /protein_end="1378"
                     /protein_start="1349"
                     /score="39.2"
                     /tool="antismash"
                     /translation="PPGACGELMITGWQVSRGYLNKPEKTAEV"
     CDS_motif       8194..8256
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg74_4_0013"
                     /evalue="1.60E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg74_4"
                     /protein_end="1431"
                     /protein_start="1410"
                     /score="33.1"
                     /tool="antismash"
                     /translation="IGRKDSQVKIRGFRIELSEVE"
     aSDomain        8554..8736
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg74_4_PP-binding.2"
                     /evalue="1.70E-09"
                     /label="ctg74_4_PP-binding.2"
                     /locus_tag="ctg74_4"
                     /protein_end="1591"
                     /protein_start="1530"
                     /score="30.0"
                     /tool="antismash"
                     /translation="DCIAEVLGYTDFGITTDIYKAGLTSITAIKLNILISKAFDIVIKT
                     SDIKNHPTIRMMEEFV"
     aSDomain        8773..9600
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg74_4_Condensation_LCL.2"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="2.70E-38"
                     /label="ctg74_4_Condensation_LCL.2"
                     /locus_tag="ctg74_4"
                     /protein_end="1879"
                     /protein_start="1603"
                     /score="123.6"
                     /tool="antismash"
                     /translation="ESYPLTNTQEGIFIECTANMGSTIYNIPYLLKLDNKVDLDRLAEA
                     IDSTVEAHPYLKTRLFMDDNGNVLQKRNDGLSYKTPILNGMNRDTLVRPYMLFNEQLFR
                     FEIYRTCDGNYLFLDLHHIVADGTSLAIIINDINRAYSGEKLEPEGYTSYDLALDNRDA
                     LAGDIYKNAENYYKSVFEHAGGSISFYPDKNGAAPTAELYHRETRSISVQNVKEFCKKH
                     GITENVFFISAFGITLGKYNFKKDAVFTTIYHGRNDSRLSETVGMLVKTLPVFC"
     aSModule        8773..12579
                     /complete
                     /domains="nrpspksdomains_ctg74_4_Condensation_LCL.2"
                     /domains="nrpspksdomains_ctg74_4_AMP-binding.3"
                     /domains="nrpspksdomains_ctg74_4_PCP.1"
                     /domains="nrpspksdomains_ctg74_4_NAD_binding_4.1"
                     /locus_tags="ctg74_4"
                     /monomer_pairings="X -> X"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       8839..8949
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg74_4_0014"
                     /evalue="2.50E-07"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg74_4"
                     /protein_end="1662"
                     /protein_start="1625"
                     /score="23.1"
                     /tool="antismash"
                     /translation="TIYNIPYLLKLDNKVDLDRLAEAIDSTVEAHPYLKTR"
     CDS_motif       9130..9195
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg74_4_0015"
                     /evalue="1.60E-07"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg74_4"
                     /protein_end="1744"
                     /protein_start="1722"
                     /score="23.9"
                     /tool="antismash"
                     /translation="LHHIVADGTSLAIIINDINRAY"
     CDS_motif       9514..9594
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg74_4_0016"
                     /evalue="3.60E-02"
                     /label="C5_starter_265-294"
                     /locus_tag="ctg74_4"
                     /protein_end="1877"
                     /protein_start="1850"
                     /score="6.8"
                     /tool="antismash"
                     /translation="VFTTIYHGRNDSRLSETVGMLVKTLPV"
     aSDomain        10045..11217
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg74_4_AMP-binding.3"
                     /evalue="2.00E-94"
                     /label="ctg74_4_AMP-binding.3"
                     /locus_tag="ctg74_4"
                     /protein_end="2418"
                     /protein_start="2027"
                     /score="308.4"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FKEMAARYPDRPAVRDDSGDFTYRELDRMSDYIAQKLTENGFGPE
                     QAAGILCGRTKEYTVAYVGVMKAGGAYVPLDPEYPQSRIEYMLKDSGARNLLVIDQYQN
                     LVEFYDGNVISLDSVSDEAEDFELSAELISPKPENLAYMIYTSGSTGKPKGVMIEHRNL
                     LNLIEYITLSRNTSPDDIVAEFASFCFDASVIDLFAPLTAGAVLYILPESIRKDAIAIS
                     RYIKEKEITTVTFPTQMGELVAELLEDAPALKFVTLGGEKFKHYRNRTYQMINGYGPTE
                     NTVSSTEFLVDRQYDNIPIGKSQRNVRSYIVDENLNRLPVGASGELCHAGRQIARGYHN
                     LPEKTASVFVENPFAVCEQESRLYRTGDMVRMKGDGNIEYIGRIDSQVKIR"
     CDS_motif       10234..10272
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg74_4_0017"
                     /evalue="3.30E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg74_4"
                     /protein_end="2103"
                     /protein_start="2090"
                     /score="17.1"
                     /tool="antismash"
                     /translation="GVMKAGGAYVPLD"
     CDS_motif       10465..10524
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg74_4_0018"
                     /evalue="8.00E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg74_4"
                     /protein_end="2187"
                     /protein_start="2167"
                     /score="33.7"
                     /tool="antismash"
                     /translation="AYMIYTSGSTGKPKGVMIEH"
     CDS_motif       10873..10902
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg74_4_0019"
                     /evalue="9.60E-02"
                     /label="NRPS-A_a5"
                     /locus_tag="ctg74_4"
                     /protein_end="2313"
                     /protein_start="2303"
                     /score="6.0"
                     /tool="antismash"
                     /translation="YGPTENTVSS"
     CDS_motif       11002..11091
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg74_4_0020"
                     /evalue="1.90E-12"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg74_4"
                     /protein_end="2376"
                     /protein_start="2346"
                     /score="39.3"
                     /tool="antismash"
                     /translation="PVGASGELCHAGRQIARGYHNLPEKTASVF"
     CDS_motif       11182..11247
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg74_4_0021"
                     /evalue="1.00E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg74_4"
                     /protein_end="2428"
                     /protein_start="2406"
                     /score="36.7"
                     /tool="antismash"
                     /translation="YIGRIDSQVKIRGYRVELGEIE"
     aSDomain        11533..11733
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg74_4_PCP.1"
                     /evalue="6.80E-21"
                     /label="ctg74_4_PCP.1"
                     /locus_tag="ctg74_4"
                     /protein_end="2590"
                     /protein_start="2523"
                     /score="66.2"
                     /tool="antismash"
                     /translation="RALCEIFEKALGIERVGIEDNFFELGGSSLTASKVAVMCLSKNIS
                     LVYADIFKYPTVRELAALVDDD"
     aSDomain        11866..12579
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg74_4_NAD_binding_4.1"
                     /evalue="1.40E-35"
                     /label="ctg74_4_NAD_binding_4.1"
                     /locus_tag="ctg74_4"
                     /protein_end="2872"
                     /protein_start="2634"
                     /score="114.5"
                     /tool="antismash"
                     /translation="VTGATGFLGIHVLKAFLDNYDGKVYCLVRKGKYESPEKRMMNMLM
                     YYFDDPYKELFESRIICVDGDITSKEQVTGFSEYKFSTIINCAACVKHFAADDVLERIN
                     VQGVENLIDFCKNNGRRLIQISTVSVAGEGSDGVPPMSRVFCENDLYIGQNITNEYIRT
                     KFLAERAVLEAVSEGLDGKVVRVGNLMSRNSDGEFQINFITNGFLRSLRGYAAVGKFPM
                     GGMHEVAEFSPIDSTA"
     CDS             12968..13270
                     /locus_tag="ctg74_5"
                     /transl_table=11
                     /translation="MEIITKTEGNKATMEISGWLDTQTAPQLGEALSGLEDSITSLVFD
                     FTNLEYISSAGLRQVIVAYKKMAQKDGFKIINVSDEVYDVFSLTGFDSKIDIQKK"
     CDS             13282..13929
                     /NRPS_PKS="Domain: ACPS (98-159). E-value: 2.8e-13. Score:
                     41.7. Matches aSDomain: nrpspksdomains_ctg74_6_ACPS.1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1012:4'-phosphopantetheinyl transferase (Score: 129.3;
                     E-value: 2.1e-39)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg74_6"
                     /transl_table=11
                     /translation="MQKLYRININHFEDPLKNERLLDLVGIRRREKVIRYRMPDDRKRS
                     LGAGIIIRKILDENGLTESCLRYSDNEKPVVDGLFFNVSHAGDYVVGVLSDCEVGCDIE
                     KNANAPLEVAEHYFYHSELAYIKAAKNKDKAFFTLWTLKESYMKMTGRGMSLPLDSFEV
                     VPTEEGFVLGKSSERPCFFETMEFDGYIFSVSSERAFSLHNPLEIVFDDIYV"
     aSDomain        13576..13758
                     /aSDomain="ACPS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg74_6_ACPS.1"
                     /evalue="2.80E-13"
                     /label="ctg74_6_ACPS.1"
                     /locus_tag="ctg74_6"
                     /protein_end="159"
                     /protein_start="98"
                     /score="41.7"
                     /tool="antismash"
                     /translation="VGCDIEKNANAPLEVAEHYFYHSELAYIKAAKNKDKAFFTLWTLK
                     ESYMKMTGRGMSLPLD"
     CDS             complement(13944..14405)
                     /locus_tag="ctg74_7"
                     /transl_table=11
                     /translation="MEDVLGLGRIFDMLGYLCIYDGDYEVTYSEFDGDNLILKLKLPCT
                     LPQEFSNGNTDFYLTGKDEEINLIIKTTDGKLKQYYADYKDYYYLPEEDTVIPKSLGSG
                     IDRKHRKAATRNTCYTWFTCSDAFLSSPVQQKQYLTYTLSCLIGTLECV"
ORIGIN
        1 tgagatgacc ttaaatcaga gaatactcaa tcaagtcaag tattttccta agttgagatg
       61 actgcaaatc agagaacatt taatcaagtc aagtattttc ccaagttgag atgaccttaa
      121 atcagagaac actcaatcaa gtcaagcact gagccagagt gtgtttggaa aatcattccc
      181 acaatctgca tgccccactt tgcggtatat tttgcccgaa ttcggttgcc gtagctcgcc
      241 gttacgacgc tttcatccga acaaaatctc ccataaattg tgacgtacat cttgcgaaaa
      301 gcatttttca aacacgttct aggttgactt cgaatcataa atcccccact cacaaattaa
      361 tcaattcaaa ctaagaaaag aggagaagat tatgcaagga ttacgaaata tgctattaca
      421 ggagcagaaa catttgcagg aaattgcaga taaagccagg atgggtatga gtgtagaacc
      481 agaaggacat cttcggattt ctagggataa aaacaagcct cgatattatc aatgtataga
      541 tggtaataat gaaatttata ttccgaggtc gaataaagag ctgcctaaac tgctggcaca
      601 gagtacatat aatagaactg tgttgaaaaa agtagaaaca aggcttaaac aaataaaaaa
      661 aatactgcag gattatacag atgatgaaat cgaaagaata tatacatcaa tgcacaaaga
      721 aagacaattg ttggtgacac caatagaacc gacatggaat caattactta tgaaatggta
      781 tgaagaagaa tatcagggaa aagaatttaa agaaggaata ccggtaattc ttaccgaaaa
      841 gggggaaagg gtaagatcta aatctgaaaa aataattgca gattatttat atagaaagaa
      901 tattctctat aaatatgaga aaccgcttta tttgaatgga tatggcatag tatatccgga
      961 ttttacatta ctttccagaa aaacaggaaa ggaaatttat tgggaacatg aaggaatgat
     1021 ggatgatcag gaatatgcaa gaaaagcaat acaaaaaata gaatcttatc aaatgaacga
     1081 tatttatcag gctgatcggc tgattcttac ttttgaaacc aaacaatgtg ttttaaattc
     1141 aaaaataata gaaaatctga cagccagata tttgtttgaa atgatataac tgaaggtaat
     1201 aatacaaatg ccggaggaat agacagaggg caggaatgag ggcttaaaag agcttcccta
     1261 ttcctgcttt tctttttcgt gactttccga tactggaggt tcaatccttc tatgatattt
     1321 gttgtgtaca tattgcgtct gatatcatta gaaaattgaa aaaagtgact tcaaatcaca
     1381 aaattcccaa ttaaatcaag cacacccccg agtcagagcg tgtttgaaaa atcattccca
     1441 caatctgcac gccccacttt gcggtatatt ttgcccgaat tcggttgccg tagcccgccg
     1501 ttatgacgct ttcattcgga caaaatctcc cacaaattgt gacgcgcatc ttgcgaaaag
     1561 cattattcaa acacgctcta atcttcagag ttagattgac ttgaaattgt aaaattttaa
     1621 attaagtcaa gtatttcttg aagaaaagat gactaaaaat tataaaaccg taaatcaggt
     1681 caagcattgc ccgaggaaaa gttgactgta aattatataa ccgcaaaata agtcaagcat
     1741 tgcccgagga aaagttgact gtaattcata aaacaacaaa acaagtcaag cattccccgg
     1801 ggaaaagctg actgtaattc ataaaacaac aaaacaagtc aagcattccc cgagaaaaag
     1861 ctgactgtaa ttcataaaac aacaaatcaa gtcaagcact cctccgagac acgttgactt
     1921 catttataaa aaaccaaatc aagtcatccc ttctccccaa caccatccct caaaaagctc
     1981 aattcctaca ggatatgaga ggtaatagaa aattgtgtgt ctgactcatt aatttgagaa
     2041 gaggagaaat ataacaatac tttcaagcaa tatttatttg ctatatttgc cttcttgcac
     2101 cttttattaa cttgccattt atcgcactaa atggtaaaat ttaaatatct tacagtttta
     2161 cggcacaata ttttgaaaaa actgaaaaca aaggagagga agcgatggaa gagagaaata
     2221 acagactgct gaatgcgaag ctgaacaagt atattgttcc ggggattatg atgtctctgg
     2281 cacttcagct ggggaatatt gtggatacga tatttgtaag taatctgata ggtgtggagg
     2341 caatgtctgc agttaccctg agcctgcctg tagagacgct tgttcagctt acgggttact
     2401 gccttggtat cggcggttcc atagcagtgg gaaacatgct tggcaaacga gacaaagaag
     2461 gggcatcgaa attgttttct gccacattta tagtaacact tgtggtggga atcatttttt
     2521 caatctgcgc ccttcctgca gcagaacctg ttgccagact tctggtatca ggtgacggtg
     2581 tcctgaccgg ttataccaga gattacatac gtgtaagtat gctgggggca ccggtgatcg
     2641 gaattggact gatgatggtc aattaccttg gggtggagaa tcatccggag ctggcatcag
     2701 cctaccttat cgcagccaat gtgatcaatc ttgtgctgga ctatatattc ctcagatata
     2761 ctccgctggg aattacaggt gcatccttat caactgttct tggtttcctg tttgcaatgg
     2821 gaatttttgt gctttatatc cgctctgata agcgaaacct ccacctgatc ctgctaaagc
     2881 caggcgaact tggaatcaca aaggaagcaa tcatcacagg cgtgccaatg ctgatcttta
     2941 tggcagctaa ttttgtaaag gcgcttggac tgaataccat tatcatgaac cagctgggcg
     3001 aggaaggtat ggcagtattt actgtctgtg acaatgtgct gctgatcgtc gagatgctta
     3061 caggcggaat catcggtgtg atccccaatg tggcaggaat cctttttgga gagaaggact
     3121 acgtgggaat ccgggttctc tgtaaaaaga tgttgaaata cagttatatc ctgctggctg
     3181 tgatctttgt ccttattatg ctgtttaccg aggaaattac tgtcatgttc ggaagcggcg
     3241 gtggcgagct gggcagccat atggtccagg cgctgcgcat ctttgctttg tgtgtggcac
     3301 cttatctgtg gaataagttt attatcagct attacgagtc cattgaggag acagccattg
     3361 caagttttgc cacatttctg gagaatgcgg tggtagttct gcctgcaacc ctggtgggaa
     3421 tccttgtatg gaaacagatt gacgggatcg gtatcgacgg aattgcagca ggatttgttg
     3481 ccactgagat cataactgca gttgcagcct gtattttcag aaaaatcagg cataagaata
     3541 caagctttta tattgttcct gacaaaaatc cggggattaa tctggatttt tccattaaga
     3601 gtaccatgga ggaagcacaa acggttcata agaggatcat agagttctgc caggaacagg
     3661 gagcttctaa aagcaaggca aatcttgccg cagtgtgtgc ggaggaaatg actgtaaata
     3721 ttatacgatt cgggggaaaa acctccaact ggatcgacat taacctctgt ctggaggatg
     3781 agctctgcag actgaggatc agagataacg gtgtaaattt caaccctctg gaatatcagt
     3841 atgacagtga agactttgat atacatggga ttgaacttgt caagaaggta tcaaaatcca
     3901 tggattatat tcgtgcgatt gatatgaata ataccataat atctttttag gaggtacatg
     3961 aaaatgaaaa atattaatga aaggaacaat tttgtttttg agtttcggcc ggtaacagaa
     4021 ttgttcgagg aacaggtgaa gcttcatccg gagaaatgtg cagttgtctc cggcaaagag
     4081 agcttcacct atgcacagct caacgaacgg gccaacagga ttgccaatgc acttgtggaa
     4141 aaaggtgtca gacgggagac tatcgtaggt gtggttcttg agagatgctg tgatttctat
     4201 gcagtgcgac agggtatcct gaaggcagga ggcgcatttg cagttgccac accggattat
     4261 cctgatgaca ggatccggta tatttttgag gattcaggag ctccttttat tatcacaaca
     4321 aaggagatcg cagaggaacg aagggaactg tttgctaagc ttccctgtac agtacttctg
     4381 atcgaggaac ttctggagaa tgagaatgca gagaatcctc aggtaaagat cggggagcat
     4441 gatctttgtt attgtatcta tacttccggt tccacaggca agcccaaggg tgtgctgatc
     4501 gaacatatca accttgccaa ttttgtaaat ccggatccga aaaatgcgga aacttatggt
     4561 tatgtaagca gaggaagtgt atctctttcc atggcagcca tgacctttga tgtgtctgtt
     4621 ctggaggaat ttctgccact taccaacggg atgactgcgg tgatcgcctc tgatgaggag
     4681 attctgaatc ctcttatgct gggtgagctg atcgtcagaa ataaagtgga tattatgacc
     4741 acaactccta cttacctgtc caatatgatc gatctgcccc agcttgaaaa agcagtttct
     4801 cagattaagg tgtttgatgt aggtgcagag gcttttcctc cggctctgta tgacaagatt
     4861 cgcagagtaa acccggatgc ttacattatg aatggttatg gacctacgga aactaccatc
     4921 agctgtacca tgaaggtaat tacggacagc agaaacatta ccattggtac gcctaacggt
     4981 aatgtgaagg tatatattgt agataaagag aataagatcc ttccggacgg agagaccgga
     5041 gagcttgtga tcgcaggact gggcgttggc agaggttata tgaatctgcc ggataaaaca
     5101 gaggctgtat tcattgatct taacggagag agagcttata agaccggtga ccttgcaagg
     5161 atcagccctg agggtgagat tgaatttttc ggaagaatag acaatcagat caagcttcgc
     5221 ggtctgagga ttgagcttgg tgagatcgag gaagtgatca attcctatga gggaatcatt
     5281 accagcatta ctctgcctgt agataacaaa ttcctctgct gctattttat ggctgaccgc
     5341 cagatcaata cagaggagct ttctgcctat gcatcagagt ccctggctca ttatatggtt
     5401 cctgaggttt ttgtccaact ggaaaagatg cctgtgacac agaatggcaa aattgataag
     5461 aaagcactgc caaagccggc tgcacagcca aagaatctga aagaacccca gactcctatg
     5521 cagaagaaga tttttgaaat cgttgcagac gttgtggaga atgatttttt tggaactgac
     5581 acaagttttt acagggcggg gctgtcttct atcagtgcca tgaagctttg tattctgatc
     5641 tcagaggaat tcggagtgac tgtgaaaacc agtgatattc acgaaaacaa tacggtggag
     5701 aaactggaaa aatatgtgat gcttgcaccg aagatcagaa cctatgaaaa gagagaagtt
     5761 taccctctta ccggctccca gaagggtatt tttgcagagt gcatgaagaa tcctgagagt
     5821 acggtataca atattccgtt cctgtttgaa ctggaaagct ctgttgacgt tcagaagctg
     5881 tcagatgcca tttctcagat gatcgctgca catccgtatt tgctgacaaa ggtttattta
     5941 agtgacagcg gagagatggt gcagaagcct tgtgaggaag cctttgtacc agaggtggtc
     6001 cggaccacaa atgagcagtt tgaaaagata aaagatgagc tggtgcgtcc ctttaagctg
     6061 gaaaagggac ggctgttccg ggcggggatt tatgtgacag aagacaggaa atatcttttt
     6121 acagatttcc accatatcct ggcagatggt aattcctatg atattatttt tgaggatatc
     6181 gatcgggcct atctgggtga gaaattggag aaagaatcct acacaggctt tgatgctgcc
     6241 cttgatgaag aacagcagat gaaagaggga aaatataaga aggccgagaa atattatgac
     6301 agtattttcg agggaattga gacagaatcc ctgcctcttc ctgactgctc aggaaagact
     6361 cctgagagag gatatctgtc gatgcctgtg gacaccggag agtctctggt actttctgcc
     6421 tgcgagaagc tgggggttac tccaaacatt ctgtttacag gtgtattcgg cattctcatg
     6481 agcagatatt ccaattccga ggagagtctt tttgcaacta tttataatgg aagaaatgat
     6541 tccagactgg agaatacagt ctgcatgctt gtaaagactc tgccggttta ctgttcctgt
     6601 gatccgaaag tcaccataca ggcctatatg acagagctct ctgagcagat tctgtcttcc
     6661 atggcaaatg atatttttcc gttctctgat atctgtgcaa agtacgggat taattctgat
     6721 ctggtatttg catatcaggc agagcttggg gatgatttcc cgatcggtga tactgttgcc
     6781 aggggccatg acctttctcc ggatatgtca aagatgcctc tgttgatcca ggtaagagaa
     6841 tacgatcata aatatgtgct tactgcagaa taccgcagtg acatgtacag tgaagccttt
     6901 gtacgtggaa tgctggaatc ctatgaggca gctatggatt ccctgctgaa agcaaaatat
     6961 atttcggaag tttctgttct ttcccaaaat ggagcggaca aaattgcgga atttaataat
     7021 actgcctgcg aatatgacag aagtaagacc atcgctgata tgtttgagga gctggtacag
     7081 accattcctg accatacggc tgtggtattt aaggataaaa aatatactta cagagaactg
     7141 gatgagatca gcgacagact tggaaaatat atcgcatccc agggaatcgg cagtgaggat
     7201 gttgtttcca ttctgatccc ccgctgtgaa tatatggcga tcgcgccgat gggcgtgata
     7261 aaggcaggtg cagcttacca gcctctggat ccaacctatc ccagggaccg cctgatgtac
     7321 atgatggagg attcctctgc aaagcttctc attgctgaca gagagcttct tcctctggta
     7381 gacggatata aaggaccggt gctgtttaca gatcagatct ggcagatgga ggatagggat
     7441 gttgtgctta agaagccgca gctgcatgat ctgtttatcc ttttgtatac ttccggttcc
     7501 acaggtgtgc caaagggctg tatgctggaa tatggaaata ttactgcttt ctgtcactgg
     7561 ttcaagaggt attatggcat agattcggat tccagggtag ctgcatatgc ttcctttggt
     7621 tttgatgcct gcatgatgga tatttacggt gccatcacaa acggtgcaca gcttcacatt
     7681 attccggagg agatccgtct ggatttcatt ggactgcagc gctattttga ggaaaatggc
     7741 atcacgcatt cctttatgac tactcaggtg ggaaggcagt ttgcgctgga gatggattgt
     7801 aagagcctga gatatctttc tgtaggagga gagaaactgg ttccatgtga gccgccaaaa
     7861 gattataagt ttatcaatgc ttatggacct acagaagcga ctatttttac gactgtattt
     7921 gaagtggaca aatattatcc aaatgtcccg atcggaaaag cacttgacaa tgtgaagctt
     7981 tatattacag acaagctggg gcatatgctt cctcccggtg catgcggaga gctgatgatc
     8041 accggctggc aggtttccag aggatatctt aacaagccgg aaaaaactgc cgaggtctat
     8101 acaaagaatc tttatgatga tacaccggga tacgaagtga tgtatcattc aggtgatgtg
     8161 gcaagatttc ttccggatgg aaatatccag atcattggca gaaaggattc ccaggttaag
     8221 atcagaggtt tcaggattga gctttctgag gttgaggaag tgatccgcag atatgagggc
     8281 atcagggatg ccactgtagt tgcctttgat gatccaaatg gtggaaaata tattgctgcc
     8341 tatgtggtat cggacagcac tgttgatatc aatgccctga atgattttat taaagagaca
     8401 aagcctgcct atatggtacc tgcagttacc atgcagattg acaaaattcc tctgaaccag
     8461 aaccagaagg taaataaaaa ggctcttcct ctgcctgaga aaaaagcagc ggagatcatt
     8521 aagcctgaga atgaggttca gcagatatta tttgactgta tcgcagaggt tctggggtat
     8581 acggattttg ggattaccac agatatttat aaggcaggtc tgacatccat cactgccatt
     8641 aagctgaata tcctgatctc caaagccttt gacattgtga tcaaaacttc agatattaag
     8701 aatcatccca ctatccgaat gatggaggaa tttgtaaaaa ctgcgggaaa agaaagcaaa
     8761 agagaagtac aggaaagtta tcctcttacc aacactcagg aggggatttt cattgagtgt
     8821 actgcaaata tgggttctac catttacaat atcccgtatc tgttaaagct tgataacaag
     8881 gtggatctgg acagactggc agaagccatt gacagtactg ttgaggcgca tccttatctg
     8941 aaaacccgtc tgtttatgga tgacaacgga aatgtacttc agaaacgaaa cgatgggctc
     9001 agttataaaa caccgatttt aaacggaatg aacagagaca ctctggtacg tccatatatg
     9061 ttgtttaatg aacagctttt ccggtttgaa atctacagaa cctgtgatgg caattatctg
     9121 ttcctggacc ttcaccacat tgttgccgat ggtacatctc tggctattat aattaatgat
     9181 attaacagag cttacagcgg tgagaagctg gaaccggaag gttatacttc ctatgatctg
     9241 gcactggata acagagatgc cctggcaggt gatatctata aaaatgcaga gaattattat
     9301 aagtcagtat ttgaacatgc aggtggaagc atcagcttct atccggacaa aaacggtgcg
     9361 gctccaacag cagaacttta ccacagagag accagatcca tttccgtgca gaatgtgaag
     9421 gaattctgta aaaagcatgg aattacggag aatgtattct tcatttccgc ttttggtatc
     9481 acacttggaa aatataattt caaaaaggat gctgtattta ccactattta ccatggaaga
     9541 aacgattcca gactttcgga aacagtgggt atgctggtaa aaacactccc tgttttctgc
     9601 gatttctcag gaacagctaa agattgcctg agcggtgtac agaaacagct gatcgattcc
     9661 atgaacaacg atatttatcc tttctcacag atcagccatg agtttgatat taaggcagat
     9721 gccatggtta tttaccaggg cgacaatttt gcttttgaca ccattggcgg ggaatatgca
     9781 caggaggagc ctgtcagcct gaacatggca aaggcaccgg tttctgtcag catttccatt
     9841 gaaaagaaca gatttgtctt tgagattgag tacagagggg atatgtacca tgaggaaact
     9901 atccggtatc tggctgacaa tctggaaacc actgcagagg gaatcttaag ggaatgcgat
     9961 ccggctgata tccggctgat gtttgaggaa aaaactcaga tggaggatat tccggaacat
    10021 gcaggaaaga ccttcataga tctgtttaag gagatggctg ccagatatcc ggacagaccg
    10081 gcagtgcggg atgactccgg agattttact tacagagagt tggacagaat gtctgattat
    10141 attgctcaga agcttacgga aaacggattt ggcccggaac aggcagcagg tatcctgtgc
    10201 ggcaggacaa aggaatatac agtagcctat gtgggtgtta tgaaggccgg cggagcctat
    10261 gttcctctgg atccggagta tccacagagc agaattgaat atatgctgaa ggattcagga
    10321 gcaagaaatc tccttgtgat cgatcagtat cagaatcttg tggaatttta tgacggaaat
    10381 gtgatcagtc tggacagtgt gtcagatgag gctgaggatt ttgaactttc tgcagagctt
    10441 atttctccga aaccggagaa ccttgcctat atgatctata cctcaggctc cacaggaaag
    10501 ccaaagggtg ttatgatcga gcacagaaat ctgttgaacc tgatcgaata tatcacactg
    10561 agcagaaata cttcaccgga tgacattgtg gcagagtttg cgagcttctg tttcgatgcg
    10621 tcagtgatcg atctgtttgc acctcttacc gcaggagcag tcctgtatat tttaccggag
    10681 agtatccgta aggacgccat tgccataagc agatatataa aggaaaaaga gatcaccacc
    10741 gtaaccttcc ctacccagat gggagaactg gttgcagaac ttctggagga tgcacctgct
    10801 cttaaatttg ttacacttgg cggcgagaaa ttcaagcatt accgtaaccg tacctatcag
    10861 atgattaatg gctacggtcc tacagagaat acggtttctt ccacagagtt tttggtagac
    10921 agacagtatg acaacatccc gatcggaaaa tcacagcgga atgtgcgcag ctacattgtg
    10981 gatgagaatc tgaaccggct tccggtgggt gcgtccggcg aactttgtca cgcaggaagg
    11041 cagattgcca gaggatatca taatcttccg gaaaaaacag catctgtgtt tgtagaaaat
    11101 ccatttgctg tatgtgagca ggaaagccgt ctttacagga ccggtgatat ggtccgtatg
    11161 aaaggtgacg gaaatattga gtacataggc cggatcgatt cacaggtgaa gatcagagga
    11221 tatcgtgtgg agcttggtga gatcgaaggt gcccttctga aacatgagct ggtgaaaaat
    11281 gcagccgtta cagtaattga aaagggtgga aataaatata tcacagctta ttatacagga
    11341 gaagccatcc cggaggatga actgaagacc ttcctggagc cgctgatccc ggattatatg
    11401 atgccgtctt tctttgtcag cattgaggaa atgcctgtga caccgggcgg taagattgat
    11461 aaaaaagcac tgccaatgcc ggaggtaacc acgaacactg ccagctatgt agagccggtt
    11521 acagcagctc agagagcact ctgtgagatt tttgagaaag cactgggaat tgaaagagta
    11581 gggattgagg acaacttctt tgagctgggc ggatcttccc ttactgcatc caaggttgct
    11641 gttatgtgtc tgtcaaagaa tatttcactg gtatatgcgg atattttcaa atatcctact
    11701 gtacgggaac ttgcagctct ggttgatgat gacggagtta cagaggctgc acagagcaag
    11761 aatgaatttt cggattataa ctataacagg atccagaatg tgatcagcgc aaatacagaa
    11821 gaaaatgcag accggatcac aaaggaaaag ctgggagata ttatggtcac aggtgccaca
    11881 ggtttcctgg ggatccatgt ccttaaagca ttccttgaca attatgacgg taaggtttac
    11941 tgtcttgtac gtaagggcaa atatgaatcg cctgaaaagc gaatgatgaa catgctgatg
    12001 tactattttg atgatccata caaagagctg tttgaaagcc gtattatctg tgtggatggg
    12061 gatattacct caaaggaaca ggtaacagga ttttcagaat acaaattcag caccatcatt
    12121 aactgcgctg cctgcgtaaa gcattttgcg gctgatgatg tactggaaag aattaatgtg
    12181 cagggtgtgg aaaatctgat cgatttctgt aagaataacg gccgcagact gatccagatt
    12241 tctacggttt ccgttgcggg agagggttct gacggtgttc cgccaatgtc cagagttttc
    12301 tgtgagaatg atctgtacat cggacagaat attaccaacg aatatatccg caccaaattc
    12361 ctggcagaga gggcggttct ggaagcagtt tccgagggac tggacggcaa ggtagtccgg
    12421 gtaggtaatc tgatgagccg aaactctgac ggcgagttcc agattaattt cattaccaat
    12481 ggattccttc gcagcctgag aggttatgcg gctgtaggta aattccctat gggcggtatg
    12541 catgaggtgg cagaattctc accgattgat tctactgcgc tggcagttct gagactggct
    12601 cagaccgacc ggagatttac tgtattccat gcatgtaaca gccatcatat ttatatggca
    12661 gacctgatct acgcaatgcg cagctatgga ttcaggattg atattgtaag agatgaggag
    12721 tttgaggcag cagtgaagga atttgcaaag accggtcagg attctgatgc ggtttccgga
    12781 ctgatcgcct atacctcaca taatgaaaat gaaatctata ccattgatta cagcaatcgt
    12841 tttacagcac aggttctgta caggctggat tataaatggc cggttacaga tgacagatat
    12901 ctggaaaatg caattgcagc acttgacaga cttacatttt ttgattgatt caggagggaa
    12961 aattacaatg gaaattatca caaaaacaga aggtaacaaa gcaactatgg aaatcagcgg
    13021 atggcttgat acacagacag ctccccagtt aggggaggct ctgtccggac ttgaagacag
    13081 catcacaagt ctggtatttg attttacaaa tctggagtat atttcatctg caggcttacg
    13141 tcaggtgatc gtggcctaca aaaaaatggc tcaaaaggat ggatttaaga tcatcaatgt
    13201 ttctgatgag gtttacgatg tattcagcct tacagggttt gacagcaaga tcgatattca
    13261 gaagaagtaa ctgttgatca gatgcagaaa ttatacagga tcaatattaa tcattttgag
    13321 gatccgctta agaatgaaag gcttctggat ctggttggga tcagaagaag agaaaaggtc
    13381 atcaggtatc gtatgcctga tgaccgcaaa agaagtctgg gtgcagggat catcatcaga
    13441 aaaatcctcg atgaaaacgg gcttacggaa agctgcctga gatattctga caatgaaaag
    13501 ccggttgtgg atggcctttt ttttaatgta tctcatgcgg gggactatgt tgtgggtgtg
    13561 ctgtcagact gcgaagtcgg gtgcgatatt gagaaaaatg ccaatgcgcc tcttgaggtg
    13621 gcagaacatt atttctacca ttcagagctt gcttacatca aggctgcgaa gaacaaagat
    13681 aaggcgtttt ttacgctctg gacattaaaa gaaagttata tgaaaatgac aggcagagga
    13741 atgagcctcc ctttggattc ttttgaagtg gttcccacag aagaggggtt tgtcctcgga
    13801 aaatcctcag aaaggccatg cttttttgag acaatggaat ttgacggtta tattttctcg
    13861 gtcagcagtg agagggcttt ttctcttcac aatccattgg aaattgtttt cgacgatatt
    13921 tatgtatgat cacagaggat ttttcagacg cattctagag ttccaatcag acaggaaagc
    13981 gtatatgtca gatattgctt ctgctgtacg ggagaactga ggaaggcatc ggagcaggta
    14041 aaccaggtgt aacaggtatt tctggttgct gctttccggt gctttctgtc aattccggat
    14101 ccgagagatt tcgggataac cgtatcctcc tctgggagat aatagtaatc cttataatct
    14161 gcatagtatt gtttcagttt cccgtcagtt gttttgataa ttaaattgat ttcttcgtct
    14221 tttcctgtca gatagaagtc ggtgtttcca ttggaaaatt cctgtggcag tgtgcagggg
    14281 agcttcagtt tcagaatcag gttgtctccg tcaaattcac tgtatgtaac ttcataatct
    14341 ccatcataga tgcaaagata tcccagcata tcaaagattc ttccaagtcc cagcacatcc
    14401 tccag
//
