LOCUS       c00010_gnlPro..        23249 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|EOMAMBIB_10.
ACCESSION   c00010_gnlPro..
VERSION     c00010_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 17:14:02
            Original ID  :: gnl|Prokka|EOMAMBIB_10
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 7779
            Orig. end    :: 31028
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23249
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[17779:21028]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13249
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
     cand_cluster    1..23249
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /kind="single"
                     /product="Putrescine2spermidine"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..23249
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Putrescine2spermidine"
                     /region_number="1"
                     /rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /tool="gutsmash"
     CDS             complement(117..1208)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1043:Periplasmic binding protein-like domain (Score:
                     107.3; E-value: 3.4e-33)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg10_9"
                     /sec_met_domain="Peripla_BP_3 (E-value: 3e-33, bitscore:
                     107.3, seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDNGKPKYFSLMEQLRSDIMSGAIRPGEKLPSENELSQKYSLSR
                     HTVRKALGILEQDGYVEAFHGRGTYCSENMRHIKNSKNIAVVTTYISDYIFPRLIQGMD
                     NVLSESGYSIILKNTANSRQKEARCLEELLKKDIDGLIIEPSKSEMICKHRNLYQNLDK
                     FEIPYVFIQGIYSEMRDKPHILMDDAQGGYLVTKYLLELGHKKIKGFFKADDMQGLERH
                     KGYVKALQESGIAYDPDDVVWFHTEDRKVKPALMAKEMVQSGQLPDGIVCYNDQIAVQV
                     MEELEKMGVRIPDDISITGYDNSLYAQRGSGITTIAHPQEKLGEMAAELILEKINGVPE
                     EESKVERLIYPELIIRGSCRKIL"
     CDS             complement(1400..2287)
                     /locus_tag="ctg10_10"
                     /transl_table=11
                     /translation="MKKLRTFAVSMIIAAIGLLIYCAGFYIKSYEQNLAARQEYAELSQ
                     MAGVKNREGAGLLADGKKTDEDSRTKNSEKKRRKKQRRSSESKNKNCTDEIRESFGISW
                     ENLRKINSQTVAWITVPGADISYPVVQAADDEYYLKHNFRGEEDLFGCIFLEHDIKKNF
                     TDSHSILYGHNIEGNMMFANLNRYEQPEFLKKCPEIEITTPKRKFLYKIFSVEQASSQS
                     PAFEYGYKLSSPAYRRQLSILKNNSMYDTGVEPDERERMVTLITCNSRLDKEIRMAVHG
                     ICHECYGIEKAEPK"
     CDS             complement(2284..6993)
                     /locus_tag="ctg10_11"
                     /transl_table=11
                     /translation="MKHNFKLKERLGALLLAMLFILQAILGLVPVCVTQAAPLTVETWD
                     SDKVVDYGYRFNMKFQPGITTYESFGCDNLDREAFSDNGKSERDTECVRVGADYKAGSA
                     GMRYNNVGKDGNGNIVDVRLILVGVENAEPRYDLRTAESIVQNKGGATFAWKDNEAYPM
                     VGFSKNSIGVFIYSVGYAKVKFQFLKHGTEETLPISGHGTIRDIDAGQGVRIPSDSSLD
                     NAYVLKNNDYLTVDGNSVSSPLGSVEPDDPRGWLNLFYNTDNFTVEFCHQFRLDKWDKS
                     REDAIAKAGSQERWAEITRNKYLDPSGNSYCPNFKGQKYCKAYAYFDFTSYCFGDVEMK
                     KAPEKRVGEANCTWEQAAATSKEKPFGIRQGQEFQYMIRAEVTPNRLKSFVVQDILEDC
                     LTIEDASKVSIVNDAGQTVTDWFDVAVEGQKVTCRAKAESLQDEAFTDNQTYTFTLKVR
                     QRPESEINISKYLAEDGYSILVPNHASMSYERTNGSGDTMDTETVWVKGVIPPELEVKK
                     NTSQYEWKTGDIIDYEVLVSQTKQDVKAVNVVITDELPSCLQFLEGQYAVETSQGGENC
                     TLTGQGENGWKAECPSLKYGETITIRFKCQASADSNGQEWENIVTATADNLINPETGEQ
                     ESRKDMAEVWPNSPQLEIDKTADKYEWQAGEQVAYRIVVNNVTAGTIAKDVTITDIGLP
                     QGLVLAGGAQSMEVLGVQQQVNYPVPDKKTGQAYEARSVDSQLNADENGFSFYCSYVPY
                     SQPVTIIFHCIAQEEANGHESVNAATVKAANTDERSDDAEVYVNSGEFWIEKSADHYEW
                     QVGEQVQYNVVVENKKAGTVARNVTVWDTGMPAGLALSSAEDVSVSGIPQNITQLTAGT
                     KDVLNQLNPEFYNETSEKPVNYEFLQEGSGWRLNISDLPANTPVMISFLCTVAEAANGM
                     ESINVANVQAQNAPVSQDDAEVYVNTAVLSIEKSFQNPYLAAGDGRAENEFRVGEQVNY
                     QVTVNNLQKGSIARNLVISDLSLPEGLALDGAEDAVTVSGVPAVIQNPVAGTDDAGNQL
                     NPENYKETVEKPVSCQVTRQGTGWIVTISDLPYQTPVTVNFRCTAQESVNGMEIVNTAQ
                     AYADNAQKVKDSSKIWVNSPVLNVEKTTDKPFYKYGDIITYRIVLTQEQTGCVARNVTL
                     QDVIDTQGVRLLKDSVILMDEKGNVADADVQINDDNTFLMSTGRTLVRDSRYSICDNDK
                     GGLFEQVMYNPLDCQEQKSMIVEYQAAVIDAALAGQKVYNTAVADSSEKIPATGETETE
                     VHSPILEIVKESDKKEYAPGEKGYYKLTVRQLREDVTDQNIVIEDKLETQGASIVKDSI
                     FVKKNGIELKDAKIEADDTGFVIQTGASLSDMDKIEVCYEVVFKTESTEPEKIVNTAKA
                     RGDISPEIAAQQEVYVKTKAEPTATPTPSATPKPTETPKPTETPKPTEVPKPTEQPKAT
                     PTPSVPGTCPKMTPVPTKAPLASYNGGNNGGTTSGSGGSSYANSGGYSGGYGSYQGGSM
                     AGSSKTGDVRPFKMMAVLGLIGMGLLTGGVVIYRRTVSGKRNIKGMPRK"
     CDS             complement(7195..7656)
                     /locus_tag="ctg10_12"
                     /transl_table=11
                     /translation="MNRKEFLEILRSQLAGQMQEGKAAAHIRYYEDYIQSQVRGGRSEQ
                     EVLQELGDPHLIAKTLIDTDDGSTQEDYGEYSSYGSSYGNETELPHQQEKRWKKVIDLS
                     TWHGRAVVIAAAAVIIVLLILIIGVAIPFFIILAIILYFLSWLKKRNDQ"
     CDS             complement(7884..8762)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CN_hydrolase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg10_13"
                     /sec_met_domain="CN_hydrolase (E-value: 9.9e-56, bitscore:
                     180.7, seeds: 52, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRNVTVAAVQMKCSKSVEKNIAHAEELVRQAAAKGAEIVLLPELF
                     ERPYFCQERRYEYYEYAQTAEENPAVRHFSRVAAELGIVIPVSFYEKEVNNTYNSVAVL
                     DADGKNLGVYRKTHIPDDHYYQEKFYFTPGDTGFKVFDTRFGTIGVGICWDQWFPETAR
                     CMALQGAELLFYPTAIGSEPILECDSMEHWRRCMQGHAASNLIPVIAANRIGEETVEPC
                     PENGMQKSALNFYGSSFITDNTGALCAELPGGEEGVLVSTFDLDALKADRLNWGLFRDR
                     RPEMYAKIVGK"
     CDS             complement(8863..9966)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PAD_porph"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg10_14"
                     /sec_met_domain="PAD_porph (E-value: 1.5e-127, bitscore:
                     417.0, seeds: 436, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEVTEKNRTKYRMPGEFEPHEGCVMIWPERPGSWNYGAREAQKAF
                     VKVAEAIGVSEKVYMLVSKAQMENAKNQLGNVSGVTLLECETDDAWARDVGATMVLDEK
                     GAVCGVDWQFNAWGGTFDGLYRNWEKDDRVAAFICRTLGCPCLDARPFVLEGGSIHSDG
                     EGTLIVTEACLLSQGRNPQMSREQIEEQLKYWLGVHKIIWLPCGIYQDETNEHVDNVCA
                     FVRPGEVVLAWTEDETDPQYAMSLADLKVLEQETDAKGRKFKIHKLPIPQKPVCLTQED
                     VDGFVFEEGEDEREAGERMAASYVNFYISNGGIILPQFGDENDKRAVEILQKCFPERRI
                     YPIDARAIIVGGGNIHCITQQIPGKNI"
     CDS             complement(10001..11122)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Orn_DAP_Arg_deC"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg10_15"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 6.5e-15,
                     bitscore: 47.1, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIDQLQTPCYVIDEKKMRENLEILKKVQEDTGCKILLAQKAFSG
                     FALYPMIGKYLAGTTASGLFEARLGYEEMGKENHVFSPAYRTEDIEELDRICDHIIFNS
                     TAQLKKFKEVCTGASLGLRINPECSTQGDHAIYDPCAPGSRLGVTRENFDVECLKWIDG
                     LHFHTLCEQNADDLEKTLQAVEEKFGEFLSEVSWLNMGGGHHITREDYDVKLLEKCIQH
                     MKETYDLDIYLEPGEAVALNAGYLVTEVMDIVENEIRTLILDASAACHMPDVLEMPYRP
                     PLKDSGEAGEKAYTYRLSSCTCLAGDVIGDYSFDREIRVGDKLYFMDMAIYSMVKNNTF
                     NGMPLPDIAVMHEDGECEVIRHFGYEDFKSRLS"
     CDS             complement(11112..12392)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Sacchrp_dh_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Sacchrp_dh_NADP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg10_16"
                     /sec_met_domain="Sacchrp_dh_C (E-value: 2.1e-43, bitscore:
                     141.1, seeds: 375, tool: rule-based-clusters)"
                     /sec_met_domain="Sacchrp_dh_NADP (E-value: 1.8e-35,
                     bitscore: 113.9, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRLLVIGCGGVASVAIRKCCQNSDVFTEIMIASRTKEKCDALKE
                     KIESTTKTKIETAKIDADNAAEVAELIRAYKPDAVLNVALPYQDLTIMDACLEAGADYI
                     DTANYEAEDTEDPTWRAIYEKRCKEKGFTAYFDYSWQWAYDEKFKEAGLTALLGTGFDP
                     GVTSVFSAYALKHYFDEIHTIDILDCNGGDHGYPFATNFNPEINLREVSANGSYWEDGH
                     WVETEPMEFKSVYDFPEVGKKDMYLLHHEEIESLAKNIPGVQRIRFFMTFGQSYLTHMK
                     CLENVGMLSTAPVEFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGVKDGKEK
                     SIYIYNVCDHQECYKEVESQAISYTTGVPAMIGSMMVVTGQWKKPGVFNVEEFDPDPYM
                     EALNKWGLPWKVCEDPELVKVWKANED"
     CDS             complement(12389..13249)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synth"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synt_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg10_17"
                     /sec_met_domain="Spermine_synth (E-value: 1.7e-53,
                     bitscore: 172.6, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Spermine_synt_N (E-value: 2.5e-15,
                     bitscore: 48.0, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELWYSEFHTGNVKLSVRINRQLFSGESEFQRIDVFESEEFGRFV
                     ALDGEIVFSDKDEFIYDEMVTHVPMTVHPNVKNVLIIGGGDGGVARELIHYPQIESIDV
                     VESDKMFVDVCAEMFPDIAQGLKDERVNIYYEDGLRFLRNKKARYDLIINDSTDPLGHT
                     EGLFTKEFYGSCYKALRDDGIMVYQHGSPFYDEDEVECRKMHRKVFRSFPVSRVYQAHI
                     PTCPSGYWLFGFASKKYHPLEDFRPERFDNLNIETWYYTTNLHRGAFMLPKYVEDLLEE
                     EENSL"
     CDS             complement(13252..14709)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_7_arginine"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg10_18"
                     /sec_met_domain="OKR_DC_1_C (E-value: 1.4e-13, bitscore:
                     43.2, seeds: 113, tool: rule-based-clusters)"
                     /sec_met_domain="OKR_DC_1_7_arginine (E-value: 3e-126,
                     bitscore: 413.0, seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDYERQQHAPIYEALERFRKKRVVPFDVPGHKRGRGNPELAQLLG
                     EKCVGLDVNSMKPLDNLCHPVSVIREAEELAADAFGAAHAFLMVGGTTSAVQSMILSVC
                     KAGDKIILPRNVHKSAINALVLCGAIPVYVNPEVNAQLGISLGMEVSQVEKAMDENPDA
                     VAVLVNNPTYYGICSDLRTIVKKAHARGMKVLADEAHGTHLYFGRNLPVSGMAAGADMA
                     AVSMHKSGGSLTQSSLLLLNKSMNAEKVRQIINLTQTTSASYLLLSSLDISRRNLALRG
                     EESFEKVAGMAQYAREEINEIGGYYAYGMDLINGTSVFDFDVTKLSIYTLGNGLAGIEV
                     YDLLRDEYDIQIEFGDICNILAYISIGDRLQDIERLVGALADIERLYKKDSTGMLSGEY
                     IAPAVVASPQQAFYAEKESLPMEQAAGRISGEFVMCYPPGIPILAPGEMVTQEIVEYIL
                     YARDKGCSMQGMEDPKVEHLQVLKGGI"
     CDS             15936..17621
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FTHFS"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg10_19"
                     /sec_met_domain="FTHFS (E-value: 2.4e-275, bitscore: 905.7,
                     seeds: 408, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGFKSDIEIAQECEMLPITQIAEKAGIDDKYLEQYGKYKAKIDYN
                     LLKESDKKDGKLILVTAINPTPAGEGKTTTTVGLADGMQRLGKSVMVALREPSLGPVFG
                     VKGGAAGGGYAQVVPMEDINLHFTGDFHAIGAANNLLAAMIDNHIFQGNALNIDPRKIT
                     WRRCVDMNDRQLRNVVDGLGGKTNGMPREDGYDITVASEIMAVLCLASDIKDLKERLSK
                     IIIGYTYGKVSEQKPVTAGDLHAEGAMTALLKDALKPNLVQTLEHVPAIVHGGPFANIA
                     HGCNSVTATKMAMKLADYAITEAGFGADLGAEKFLDIKCRMAGLKPSAVVIVATVRALK
                     YNGGVAKADLNNENLEALEKGIPNLLKHVSNIKNVYKLPCVVAINAFPTDTKAELDFVE
                     AKCKELGVNVALSEVWAKGGEGGIKLAEEVIRLVEEPNDFSYAYELEGSIEDKLNQIVQ
                     KVYGGKKVVLTANAQKQAKQLEALGFGNCPICVAKTQYSLTDDQTKLGAPTDFEVTVRN
                     LKISAGAGFIVALTGEIMTMPGLPKVPAAERIDVDETGKITGLF"
     CDS             complement(17729..19153)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lyase_1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FumaraseC_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg10_20"
                     /sec_met_domain="Lyase_1 (E-value: 1.3e-94, bitscore:
                     308.9, seeds: 17, tool: rule-based-clusters)"
                     /sec_met_domain="FumaraseC_C (E-value: 4.8e-22, bitscore:
                     70.1, seeds: 737, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKTDYRVERDSIGVKDIPEDVYYGVQSLRAAENFHITGLNMHPE
                     IINSLAYIKKAAAITNCEVGLLEKKKAQAIVQACDEIVSGKFHNEFIVDPVQGGAGTSL
                     NMNANEVIANRAIEILGGKKGDYTIINPNDDVNCGQSTNDVIPTAGKMTSLRLLQNLKK
                     QLLRLYDALNEKATEFDHIIKMGRTQMQDAVPIRLGQEFKAYSVAIMRDIHRMDKAMDE
                     MRTLNMGGTAIGTGINADEGYLRRIVPNLTEISGMDFIQAFDLIDSTQNLDPFVAVSGA
                     VKACAVTLSKMSNDLRLMSSGPRTGFGEINLPAKQNGSSIMPGKVNPVIPEVVNQVAFN
                     IIGNDVTITMAAEAGQLELNAFEPIIFYCMFQSIDTLGYAVQTLVDNCIVGITANEERC
                     RYLVENSVGIITAISPHLGYQKAADIAKKAIKTGESVRSLILKEKLMDEDELNRILDPI
                     HMTEPGISGKDYLIKK"
     CDS             19269..20204
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     58; E-value: 2.3e-18)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg10_21"
                     /sec_met_domain="LysR_substrate (E-value: 1.8e-33,
                     bitscore: 107.5, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 2e-18, bitscore: 58.0,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFQGMEYIYEVYKEKSFSKAAAALFISQPSLSANVKRVENRIGYP
                     IFDRSTKPLQLTEVGKHYIQAVEKVMDIENNLENYLLDLGNLKTGTLNVGGSNFFSSWI
                     LPPLIADFSQKFPHVQISLVEESTAKLSQFLQAGKLDLVIDNCILDNQIFERYIYQKEQ
                     LLLAVPKNYSVNTRLQKYQIPIEEIRNGQFRSSHIPSVPLNKFENEPFIILRSDNDTGK
                     RALTICQENHFSPSVVFRLDQQMTAYNIACLGMGITFIGDLLLSRVPTNSELVFYKLPG
                     QSSKRTVFFYWKKGRYISRAMEEFLKLPFS"
     CDS             complement(20316..21773)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FGGY_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FGGY_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg10_22"
                     /sec_met_domain="FGGY_C (E-value: 3.7e-38, bitscore: 123.0,
                     seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="FGGY_N (E-value: 2.4e-80, bitscore: 261.4,
                     seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYYIGIDLGTSAVKLLLMEESGKICNIVSREYPLFFPHPGWSEQK
                     PEDWFAQSMEGMKELTKDIDRAQVAGIGFGGQMHGLVTLDKDDNVIRPAILWNDGRTGE
                     ETEYLNTVIGKDKLSQYTANIAFAGFTAPKILWMQKNEPENFKKVVKIMLPKDYLAYRL
                     SGSFCTDVSDASGMLLLDVKNRCWSKEMLEICGITEEQLPKLYESWEVVGTLKPEIAKE
                     LGFSENVKVVAGAGDNAAAAVGTGTVGDGQCNISLGTSGTVFISSKNFGVDENNALHSF
                     CHADGSYHLMGCMLSAASCNKWWAEEILQTKDFAAEQAPIQKLGENHVFFLPYLMGERS
                     PHNNPDARGVFFGMSMDSTRADMTQAVLEGVAFGLRDSLEVARNLGIKIERTKICGGGA
                     KSPLWKKIIANVMNLKVDVLENEEGPSMGGAMLAAVGCGAYPDVETIGKKFAKVVDTVE
                     PDPELVAKYEERYQKFRTLYPAMKPLF"
ORIGIN
        1 actcatctcc gtaaagatcc tgtgaacctg tacaaaacca gaacttatag tttcttcctg
       61 ttttcatgat aaaattcctc ccggatttat ttttattttt tatttatttc atttgtttac
      121 aatatttttc tgcatgatcc ccgtatgatc agttccggat aaatcagtct ttcaacctta
      181 ctttcttctt caggaactcc gttgatcttc tcaagtataa gctctgctgc catttctccc
      241 agcttttcct gcggatgagc tatcgttgtg attccgcttc ctcgctgagc atacagtgaa
      301 ttgtcataac cggtaatgga aatatcatcc ggtatcctga ctcccatttt ctccagttct
      361 tccataacct gaacagcaat ctgatcattg taacaaacga ttccatccgg aagctgtccg
      421 ctctgtacca tttcttttgc catcagtgca ggttttactt tcctgtcctc tgtatgaaac
      481 cagacaacat catcaggatc ataggcaatc cctgactcct gtaaggcctt cacatatccc
      541 ttgtggcgct ccagtccctg catatcgtct gccttaaaga aacccttgat ctttttatgt
      601 cccagttcca gcagatattt tgttacaaga tagcctccct gtgcatcatc cataagaata
      661 tgaggtttat ccctcatttc tgaatagatt ccctgaataa acacatacgg aatttcaaat
      721 ttatccagat tctgataaag atttctgtgt ttacagatca tctcactttt gcttggttca
      781 atgatcagtc catcaatatc tttcttcaga agttcctcca gacatctggc ctctttctgt
      841 ctgctgtttg ctgtgttttt caggataata ctgtaaccgc tttctgaaag gacattatcc
      901 attccctgta tcagtctcgg aaaaatataa tcagaaatat atgtggtcac taccgcaata
      961 ttctttgaat tctttatatg gcgcatattc tcagagcaat aagtacctct tccgtgaaat
     1021 gcctctacat atccgtcctg ctccaggatt cccagtgctt tacgaactgt atgtctactc
     1081 agggaatatt tctgtgaaag ctcgttttct gaaggaagct tctctcccgg tcggatagct
     1141 cctgacataa tatcacttct gagctgttcc atcagtgaga aatatttcgg ctttccatta
     1201 tctgtcatgt cttcttccct cctgtattta ggatacaact tgtacgcacg tacgaacaag
     1261 ttgtttttta tgcataaatt atacaaaata tcgagagatt tttcattagt tttttccaaa
     1321 acacctcgag ggatagtgat gtgtgaacag taacagttca tcctttacga aagttaccaa
     1381 tatccgattg atttcaacat cacttcggct cagctttttc tataccataa cattcatggc
     1441 aaatcccatg taccgccata cgtatttctt tatccagacg tgaattacag gtgatcagag
     1501 tcaccattct ctccctttca tcaggctcta ctcctgtgtc atacatggaa ttatttttca
     1561 atatagataa ttgtctcctg tatgcaggac tggataactt gtatccatat tcaaatgccg
     1621 ggctttggga agatgcctgt tccacagaaa aaattttgta cagaaacttt ctttttggtg
     1681 ttgtgatctc aatttcagga cattttttta gaaattcagg ctgttcataa cggttcagat
     1741 ttgcaaacat catattacct tctatattat gcccgtaaag aatactgtgg gaatctgtaa
     1801 aattcttttt tatgtcatgt tccagaaaaa tacatccaaa cagatcttcc tctcctctga
     1861 aattatgttt caggtaatat tcatcatctg ccgcctgaac tacaggataa gaaatatcgg
     1921 ctcccgggac agtaatccag gcaactgtct gagagttgat ctttcttaaa ttttcccagg
     1981 aaatcccgaa ggattccctg atttcatctg tacagttttt gttttttgat tcagaagatc
     2041 ttctctgttt tttcctgcgt tttttttcac tgttttttgt cctgctgtct tcatcagttt
     2101 ttttgccatc tgccaataat ccggcacctt ctctgttctt cacccctgcc atttgggaaa
     2161 gctctgcata ttcctgcctt gctgcaagat tctgttcata actttttata tagaaaccgg
     2221 cacaatatat aagaagccca attgctgcta tgatcatact tactgcaaat gttctgagtt
     2281 ttttcatttc cgcggcatac cctttatatt tcttttcccg gaaacagttc ttctgtagat
     2341 caccacacct cctgtcagca gtcccattcc gataaggcca agaacagcca tcattttaaa
     2401 cggtctgaca tctcctgttt tagaacttcc tgccatggaa ccaccctgat agcttccgta
     2461 tccaccggaa tatccacccg aatttgcgta actgctgcct ccgcttccgg aagttgtgcc
     2521 tccattattt ccaccattgt aagatgccaa cggtgctttc gtcggtacag gagtcatttt
     2581 cgggcaggtt cccggtacag atggtgttgg tgtggctttt ggctgctccg tcggtttcgg
     2641 tacttctgta ggttttggtg tctctgtcgg ctttggtgtt tctgttggtt tcggtgttgc
     2701 agacggtgtt ggtgtggcag tgggttctgc ttttgttttc acatatacct cctgctgcgc
     2761 cgcaatttcc ggtgaaatat ctcctcttgc tttcgctgtg tttacaattt tttcaggctc
     2821 tgtgctttct gttttaaata ccacttcata gcagacttca attttatcca tatctgacaa
     2881 cgatgctcct gtctgaatta caaatcctgt atcatctgcc tctattttgg catctttcag
     2941 ctctatgccg tttttcttca caaaaatgct gtcttttaca atagaagccc cttgggtttc
     3001 cagtttatct tcgataacaa tattctgatc tgtgacatcc tcacgcagtt gtcttactgt
     3061 cagcttatag tatcctttct caccgggcgc atactctttc ttatctgatt ccttcacaat
     3121 ttccagaatc ggactgtgta cctctgtctc tgtttccccg gttgcaggta tcttttcact
     3181 gctgtctgca actgcagtat tgtacacttt ctgtcctgcc agggctgcat caatcactgc
     3241 tgcctgatat tccacgatca tacttttctg ttcctgacag tccagaggat tatacattac
     3301 ctgctcaaaa agaccgcctt tatcattatc gcagatacta tatctgctgt ccctgaccag
     3361 tgtcctgcct gttgacatca ggaaagtatt atcatcattg atctgtacat cagcatctgc
     3421 cacatttcct ttctcatcca tcagaatcac cgaatccttc agaagacgta ctccctgagt
     3481 atcgatcaca tcctgcagag taacattacg cgccacacat ccggtctgct cctgtgtcag
     3541 gacaatgcgg tatgtaataa tatcaccata tttgtaaaat ggtttgtccg tcgtcttctc
     3601 tacgttaaga acaggcgagt tcacccagat ttttgaggag tcctttactt tctgtgcatt
     3661 atctgcatac gcctgtgctg tatttacaat ctccatccca tttacgcttt cctgcgcagt
     3721 acagcggaaa ttaacagtca caggtgtctg atacggaaga tctgaaatcg tcacgatcca
     3781 tccggttccc tgacgtgtaa cctgacagct gaccggtttt tccactgttt ctttataatt
     3841 ttccggattc agctgatttc ctgcatcatc agttcctgcc accggattct gaataacagc
     3901 cggaacaccg cttacagtaa cagcatcttc agctccgtcc agagccagcc cttcaggaag
     3961 ggaaagatca ctgatcacaa gatttcttgc gatagatccc ttctgaagat tattaaccgt
     4021 aacctgataa ttcacctgtt ctcctacccg aaattcattt tccgcacgtc catccccggc
     4081 tgccagatat ggattctgaa aacttttctc aatagaaaga actgctgtat ttacatacac
     4141 ttctgcgtca tcctgtgaaa caggggcatt ctgcgcctgc acattggcaa cattaatgct
     4201 ttccattcca tttgccgctt ccgcaactgt gcaaaggaaa gaaatcataa ccggagtatt
     4261 tgccggaaga tctgaaatgt tcagtctcca tccgcttccc tcctgaagaa attcataatt
     4321 caccggtttc tctgatgtct cattataaaa ttccggattg agctggttca aaacatcttt
     4381 ggtccctgct gtcagctgcg taatattctg tgggattccg cttaccgata catcctctgc
     4441 cgatgaaagc gcaagtcctg ccggcatacc ggtatcccag acagttacgt tccgggccac
     4501 tgtacctgct tttttattct ccaccaccac attgtactgt acctgttctc cgacctgcca
     4561 ttcataatga tctgcagatt tctcaatcca gaattctcct gaatttacat atacttctgc
     4621 atcatcagat ctctcatctg tattagcagc ttttacagtt gctgcattta cgctttcgtg
     4681 tccatttgcc tcttcctgtg cgatacaatg gaaaataatc gttacaggct gactgtatgg
     4741 cacataagaa caataaaagg aaaatccgtt ctcatctgca ttcaactgag aatccacaga
     4801 tctcgcttca tatgcctgtc ctgttttctt atccggtacg ggatagttta cctgttgctg
     4861 aactcccagt acttccatgc tctgtgcacc acctgccaga accagtccct gcggcagacc
     4921 aatatcagta atagttacat cttttgcaat tgttcctgcc gttacattat tcaccacgat
     4981 ccggtaagct acctgctctc ctgcctgcca ttcatatttg tctgctgttt tatcaatttc
     5041 aagctgtgga ctgttcggcc atacttctgc catatccttt ctggattctt gttctcctgt
     5101 ctcaggattg atcagattat ccgctgttgc agtcacaata ttttcccatt cctgtccatt
     5161 ggaatccgca gatgcctgac atttaaaacg gattgtgatc gtctccccat acttcaggga
     5221 cggacactct gctttccatc cattttctcc ctgtccggta agcgtacagt tctcgcctcc
     5281 ctgacttgtc tctacagcat actgcccttc cagaaactgc agacatgatg gaagctcgtc
     5341 tgtaataaca acatttactg cttttacatc ctgttttgtc tgagaaacca gaacctcata
     5401 atctatgata tctcccgttt tccattcata ctgagaagta tttttcttta cttccagttc
     5461 cggtggaatc acacccttta cccacactgt ttccgtatcc attgtatctc cgcttccgtt
     5521 tgtacgttca taactcatgg atgcatggtt tggtacaaga atactgtatc catcctctgc
     5581 aaggtatttt gaaatgttaa tttctgattc cggtctctgg cgtactttta aagtaaatgt
     5641 gtaagtctga ttatctgtaa atgcttcatc ctgaaggctc tctgctttgg ccctgcaggt
     5701 cactttctgt ccttcaacag caacatcaaa ccagtctgtc actgtctgcc ctgcatcatt
     5761 cacaatactg acttttgatg catcctctat agtaagacaa tcctcaagta tatcctgtac
     5821 cacaaaggat ttcagtctat tgggtgtcac ctccgcccgg atcatatact gaaattcctg
     5881 tccctgacga atgccaaaag gtttttcttt tgatgtggca gctgcctgtt cccatgtaca
     5941 gtttgcctct cccacacgtt tctcaggcgc ttttttcatc tcaacatcac cgaaacaata
     6001 ggatgtaaaa tcaaaatatg catatgcttt gcagtatttc tgtcctttaa agttcggaca
     6061 ataactgttg cctgatggat ccaaatattt atttcttgta atctctgccc atctttcttg
     6121 agaaccggct tttgcaatgg catcttcacg acttttatcc catttatcca gtctgaactg
     6181 atgacagaat tctaccgtaa aattatctgt attataaaaa agattcagcc atcctctcgg
     6241 atcatccggc tcaacggaac caaggggtga gcttacagaa ttcccatcta ctgtcagata
     6301 atcattgttt ttcagaacat atgcattatc cagactgctg tctgacggaa tacggactcc
     6361 ctgtcccgca tcaatatcac gtatggttcc atggccactg atcggcaatg tttcttctgt
     6421 tccatgcttc agaaactgaa acttaacctt tgcgtatcct acagaataaa taaatacacc
     6481 gatactgttt ttggaaaagc caaccattgg ataagcttca ttatctttcc atgcaaacgt
     6541 agctccgcct ttattctgaa caatcgattc tgcagtgcgc agatcataac ggggttctgc
     6601 attctctact cccacaagaa tgagtctgac atcaacaata tttccatttc catcttttcc
     6661 tacattgtta taacgcatcc ctgcgcttcc ggctttatag tccgctccta cacgaacgca
     6721 ctctgtgtca cgttcgcttt ttccattgtc tgaaaaagct tccctgtcca gattatcaca
     6781 cccaaaagat tcatatgtgg taattccggg ctgaaacttc atgttaaagc gataaccata
     6841 atctaccacc ttgtcactgt cccatgtttc tacagttaac ggtgccgcct gagttacgca
     6901 gacaggcaca agccccagaa ttgcctgcag aataaaaagc attgcaagca gcaaagctcc
     6961 aaggcgttct ttcagtttga aattgtgttt cattttccgt ctcctttccg aacaaaaaat
     7021 ataaaaataa atgtgggatt tttccctgca ccaggcagga ttaaagaata gaaataagtt
     7081 gaaatgtatg attataaata ttcaagggga attaatatcg tgaaacaaga acgtttacac
     7141 ttaagatttt aagattctgc gcagggtttc ttttctgaaa ccctgcatag attttcattg
     7201 atcatttctt ttcttcagcc atgaaagaaa ataaagaata attgcaagaa ttataaaaaa
     7261 cggaatcgca actccgatta tcagtatcag taaaacaatt ataacagccg ctgctgcaat
     7321 aacaacagcc ctgccatgcc aggtagaaag atcgattact tttttccatc ttttctcctg
     7381 ctgatgagga agctctgtct cattgccata actgcttccg taagaagaat actctccgta
     7441 atcttcctgt gtacttccat catctgtatc gatcagagtt tttgctatca gatgtggatc
     7501 tcccagttcc tgcagtacct cctgctctga acgtccgcca cgtacctgag actgtatata
     7561 atcttcataa tacctgatat gtgccgctgc tttgccttcc tgcatctgcc cggcaagctg
     7621 gcttctcagg atttccaaaa attcttttct gttcatcttc tacactccat tttgccagaa
     7681 atacatatca aaactctact gctctctccg ttatcagtaa cgttcgtact cttattttac
     7741 catatatacc gcaggtagca actaatataa tcataaactt tttatgaaat tcttataaac
     7801 tcagttactg ttcactccgt tctcagtaac tgagccaaaa ttcattccag attgcctgcg
     7861 gcaatggaat tttggcttgt atgtcatttc ccgacaattt ttgcatacat ttcaggtctg
     7921 cggtctctga aaagtcccca gttcagtctg tctgccttta atgcatccag gtcaaaagtg
     7981 cttacaagca ccccctcttc ccctccgggc agttctgcac agagagcacc tgtgttgtct
     8041 gtgataaaag aagagccgta aaaattaaga gcagatttct gcattccgtt ttccggacat
     8101 ggctccactg tttcctcacc gattctgttg gcagcgatca cagggatcag gttggaggca
     8161 gcgtgtccct gcatacatct tctccagtgt tccatgctgt cgcattccag gatgggttca
     8221 cttccgatgg cagtgggata aaagagaagc tctgcgccct gcagtgccat acatcttgcc
     8281 gtttccggga accactgatc ccagcagatt ccaactccaa tggttccaaa tctggtatca
     8341 aaaaccttaa agccggtatc tcccggtgtg aaatagaatt tttcctgata ataatggtca
     8401 tccggaatat gtgttttccg gtaaacgccg agattcttcc catctgcatc cagaaccgca
     8461 acgctgttat aggtattatt gacctctttt tcataaaaac tgaccgggat cacaatcccc
     8521 agctctgccg ctaccctgct gaaatgacgc actgcagggt tttcctctgc agtctgcgca
     8581 tattcataat actcatatct gcgctcctgg cagaaatagg gccgttcaaa aagctccgga
     8641 agaagaacaa tctcagctcc ctttgctgct gcctgacgca ccagttcctc tgcatgggca
     8701 atatttttct ccacactttt actgcatttc atctgaactg ctgccactgt tacatttctc
     8761 atcctgtctg ttcctcctgc tcctgtttac ataagtaagt tttttcataa ctttcaggta
     8821 taaccctcaa acacatgact ctcaaagttt tctgcatcag ggtcagatat tttttccggg
     8881 aatctgctgg gtgatacagt gaatatttcc accgccgaca atgatggctc tggcatcaat
     8941 gggataaatc cttctttcag gaaaacactt ctgcagaatc tccactgccc ttttgtcatt
     9001 ttcatcccca aactgtggaa ggatgattcc tccattggaa atatagaaat tcacataact
     9061 ggcagccatc cgttctcctg cttcccgttc gtcttctccc tcttcaaaca caaagccatc
     9121 cacatcttcc tgggtaaggc agaccggttt ctgaggaatc ggaagcttat gaatcttaaa
     9181 ttttctgcct tttgcatctg tttcctgttc cagcaccttc agatcagcca gagacatggc
     9241 atactgcgga tctgtctcat cctctgtcca tgcaagcaca acctctccgg gccttacaaa
     9301 agcgcacacg ttatccacat gctcattggt ttcatcctga tagattccac atggaagcca
     9361 gataatcttg tggacaccga gccagtactt caactgttcc tctatctgtt ccctgctcat
     9421 ctgaggattg cgtccctgac tcagaagaca ggcctctgta acgatcagag tcccctctcc
     9481 gtcagaatgg atggaaccgc cctccagcac aaaaggtctg gcatccagac atggacaacc
     9541 gagagtcctg cagataaagg cagccaccct gtcatccttt tcccagttcc ggtaaagccc
     9601 gtcaaaggta cctccccagg cattgaactg ccagtcaact ccacagaccg cccctttctc
     9661 atccagaacc atggttgctc ccacatctct ggcccaggcg tcatctgtct cgcattccag
     9721 caaagtcaca ccggaaacat tcccaagctg attctttgca ttctccatct gagctttgga
     9781 aaccagcata tacacctttt cgctcactcc aatagcctct gcaactttca caaatgcttt
     9841 ctgtgcttcc cttgccccat aattccagga accgggacgt tccggccaga tcatcacaca
     9901 tccctcatga ggctcaaatt ctccgggcat acgatatttt gttctgttct tctctgtaac
     9961 ttccatgtct gtctcctttt ctttgatagc ccggcagata tcaggaaagc cggctcttaa
    10021 agtcttcgta tccgaaatgt ctgataacct cacactctcc gtcctcatgc ataaccgcaa
    10081 tatccggcag cggcatacca ttaaatgtat tattcttcac catagaataa atcgccatat
    10141 ccataaaata cagcttgtcc ccgacccgga tctctctgtc aaaggaataa tctccgatta
    10201 catctcctgc cagacaggtg caggaagata agcggtaggt atatgccttc tcccctgctt
    10261 ccccgctgtc cttaagaggc ggacgatagg gcatctccag cacatccggc atatggcagg
    10321 ctgcagaagc atccaaaatc agcgttctga tctcattttc cacaatgtcc ataacctctg
    10381 tcaccagata tccggcattc agggcaacag cctccccggg ctccagataa atatccagat
    10441 cataggtttc cttcatatgc tgaatacatt tttccaggag ctttacatca taatcctctc
    10501 tggtaatatg atgtccgccg cccatattca gccaggaaac ctcagacaga aattctccaa
    10561 acttctcctc taccgcctgc aatgttttct ccaggtcatc cgcattctgt tcgcagagcg
    10621 tatgaaaatg cagtccgtcg atccatttca gacattccac gtcaaagttc tctctggtaa
    10681 cccccagcct ggaacccggc gcacagggat catagatcgc atgatccccc tgagtggagc
    10741 attccggatt aatacggagt cccagactgg ctccggtaca cacttcttta aatttcttca
    10801 gctgtgctgt ggaattaaag ataatatggt cacagatccg atccagttcc tctatatctt
    10861 ctgtacggta agcaggggaa aaaacatgat tctctttccc catctcttca tatccaagcc
    10921 ttgcctcaaa cagaccgctg gcagtggtac ctgccagata ttttccaatc atgggataca
    10981 gagcaaagcc ggaaaacgct ttctgcgcca gaaggatctt acacccggta tcctcctgga
    11041 cttttttcaa aatctccaga ttctcccgca tcttcttctc atcgatcaca tagcagggag
    11101 tttgcagttg atcaatcttc attggctttc cagaccttta ccagttcagg atcttcgcag
    11161 actttccatg gaagtcccca tttgttcagt gcttccatat atggatccgg atcaaattct
    11221 tccacattaa atacacccgg cttcttccac tgtccggtca ctaccatcat ggaaccgatc
    11281 atagccggaa cacctgttgt ataggagatt gcctgggatt ccacctcttt atagcattcc
    11341 tgatgatcac atacattata aatataaata cttttctctt ttccgtcctt aacacctgtg
    11401 aaaatacagc caatatttgt tttacccact gttctcggac ccagagatgc aggatccggc
    11461 agaagagctt tcaaaaactg gatcggcacg atttcctgtc cattaaattc cacaggtgcg
    11521 gtggaaagca ttcctacatt ttccagacat ttcatatgtg tcagatagct ctgtccgaat
    11581 gtcataaaga aacggatcct ctgtactccc ggaatatttt ttgccagtga ttcaatctct
    11641 tcatgatgaa gaagatacat atccttcttt cctacctcag ggaaatcgta gacagattta
    11701 aattccatag gctctgtttc tacccaatgt ccgtcttccc agtaggaacc atttgcggaa
    11761 acctctcgaa gattgatctc cgggttaaag tttgtggcaa aaggatatcc atgatcaccg
    11821 ccgttacagt ccagaatatc aatggtatgg atttcatcaa aataatgctt cagggcataa
    11881 gcactgaata cactggtaac acccggatca aaaccggttc ccagaagagc agtcagtcct
    11941 gcttccttaa atttctcatc ataagcccac tgccaggaat aatcgaaata tgcagtaaag
    12001 cctttttctt tacatctctt ttcgtagatt gcacgccatg tgggatcttc tgtatcctct
    12061 gcttcataat tggcagtatc aatataatcc gcaccggctt ccagacatgc atccatgatg
    12121 gtaagatcct gatatggaag tgccacattc aggacagcat ccggcttata ggctctgatc
    12181 aattctgcga cctctgctgc attatccgca tctatctttg ctgtctcaat ttttgtcttc
    12241 gttgtacttt caatcttctc tttgagtgca tcgcattttt cctttgtcct gcttgcgatc
    12301 ataatctctg taaaaacatc gctgttctga cagcatttgc gaattgccac tgaagctacc
    12361 ccaccacatc cgattaccaa taatctgctc ataaactgtt ttcctcctct tccagtaaat
    12421 cttctacata ttttggaagc ataaatgctc ctctgtgaag gtttgttgta taataccatg
    12481 tttctatatt aagattatca aacctctccg gcctgaaatc ttccagtgga tgatatttct
    12541 ttgatgcaaa tccaaaaagc cagtatcccg agggacaggt agggatatgt gcctgataaa
    12601 ccctgctcac cggaaatgac cggaaaacct ttctgtgcat ctttctgcat tccacctcat
    12661 cctcatcata aaaaggactt ccatgctgat aaaccatgat tccgtcatct ctgagagcct
    12721 tataacagct tccgtagaat tcctttgtaa aaagtccctc tgtatgtccc agcggatctg
    12781 tggaatcatt gatgatcagg tcatatctgg cctttttatt ccgcaggaac cgaagaccgt
    12841 cttcataata aatgttgact ctctcatcct tcagtccctg ggcaatatcc ggaaacatct
    12901 ccgcacatac atccacaaac attttatcgg attccaccac atcaatgctc tcaatctgtg
    12961 gataatggat cagttctctg gcaactccac cgtcaccgcc gccgatgatc agaacatttt
    13021 ttacattggg atgtactgtc attggcacat gcgtgaccat ttcatcataa ataaattcat
    13081 ccttgtcaga aaatacgatc tcaccgtcca gagccacaaa tcttccaaat tcttcagact
    13141 caaacacatc gattctctga aattcacttt cccccgaaaa taactgtcgg ttaatccgga
    13201 cagaaagctt tacatttcct gtatggaact cggaatacca taattccatg atcagatacc
    13261 ccctttcaga acctgaagat gttctacctt cggatcctcc attccctgca tggaacagcc
    13321 tttgtctctt gcataaagaa tgtattctac aatttcctgt gtcaccattt ccccaggagc
    13381 aagaatcggg attcccggag gataacacat aacaaattca ccgctgatcc tgcctgccgc
    13441 ctgttccatg ggcagagatt ctttctccgc ataaaatgcc tgctgtggag acgccaccac
    13501 tgcaggtgcg atatattccc cggaaagcat acctgtgctg tccttcttat acagacgttc
    13561 aatatcagcc aatgccccta ccagtctctc aatatcctga agcctgtctc caatggaaat
    13621 gtaagccaga atattacaga tatctccaaa ctcgatctga atatcatatt catctctgag
    13681 aagatcataa acttcaatac ctgccagccc atttcccagt gtataaatgg agagttttgt
    13741 aacatcaaaa tcaaaaacac tggttccatt gatcagatcc ataccatatg cataataacc
    13801 gccgatctca ttgatctcct ctctggcata ctgcgccatc cctgcaacct tttcaaagga
    13861 ttcctctccc ctgagtgcca gatttcttct ggagatatcc agactggaca acagaagata
    13921 agaagcgctt gtggtctgag tcaaattgat gatctggcgc actttctctg cattcatact
    13981 cttattcaaa agcagcagcg aactctgtgt cagacttccg ccggatttgt gcatggaaac
    14041 tgccgccatg tcagcacctg ccgccattcc ggacacagga aggtttctgc cgaaataaag
    14101 atgggttcca tgagcctcat ctgccagcac cttcattcct cttgcatgag ccttctttac
    14161 gatagtccgc agatccgaac agattccata ataggtaggg ttatttacaa gaactgccac
    14221 cgcatccgga ttctcatcca tagccttctc cacctgactg acttccatgc caagggaaat
    14281 gcccagctgc gcattcacct ccgggtttac ataaaccgga attgcaccgc acagtaccag
    14341 ggcattgatg gcacttttat gtacatttcg cggcagaatg atcttatccc ctgccttgca
    14401 gacagacagg atcatgctct gcactgcaga tgtggttcct cctaccataa ggaatgcatg
    14461 cgctgcgcca aaagcatctg ctgcaagctc ctccgcttct ctgatcaccg aaaccgggtg
    14521 gcagagattg tccagcggct tcatagaatt aacatccagc cccacacatt tctctcccag
    14581 caactgtgca agctctggat ttcctcttcc tcttttatgt cccggcacat caaagggaac
    14641 gactctcttc tttcggaaac gttccagtgc ttcatatatg ggcgcatgct gttgtctttc
    14701 ataatccatt tgacatgttc ctcttttcct gtcgtcatgt accggcaaat acagttctat
    14761 cattcagcaa ttgtatactg cctcaaaccg gcacaatgat tcaattattt ctatatatat
    14821 atttgctata tctgcacaaa aaaagaagca gataagttca ttcaccatct gcttctctca
    14881 tgatctatag aatttctcag gctctgtctc tttatatact gaccggattt cccgtataaa
    14941 tccgtctgta tcctgtgcct gttcccgtat tctgaaatat tcatgactgc tgtcgtcttc
    15001 aatcgctggc aaatatatgc tatgctctta ttgaccgttt cacaagatga tgtgtgctta
    15061 cgcactgatt attataaagt aatcaactta taaaatttga gcttctaact caatcaataa
    15121 tgtggtgtct cccacccggc aactgccccg cctgtccgta tggcttaaca ttcagaaact
    15181 gtctctgaat gtgagcaaat atttgcatga aaacgatagt gtcttttcat actaaagatg
    15241 agaataacat atcttctgaa ctgttgtcaa ttccattttc catattttgc actagagcgt
    15301 gtctgaaaaa ggctttctgc aagatgtgcg tcacaatttg tgggatattt tgcccggatg
    15361 agggcgccgt agcgggctac ggcaactgaa ttcgggtgaa atatcccgca aagtgggggc
    15421 gtacagattg cgggaatgat ttttcagaca cgctctagct ttacccgctt tttatatttt
    15481 cttcatttat cagggaaaac tgtgtttatt ttttaacaat ttctttcctt gagaaaacgt
    15541 attttctttc atgaccaggg attacgattc tcttctctta tcaatttgca caacttttat
    15601 ccagtttact cacatttttt gacgtttcaa caaaattttc ttgacatttt tttctcaaaa
    15661 tgatatattg tattcatcaa ttgaaagaac cttcgagtac tgacggaaag agtggagtgc
    15721 aaaccacgtg gagtcggagg tttgtgggag ccgaccgtct gggcagtatt tgaaatattc
    15781 agatactggc ctttttttat aactttcagg gcagaaatca ggaataccag gcagaccggc
    15841 caatacttct ttcaattaat aattgttgct gatcgcggag tgaacagcaa cagaagtttt
    15901 tcatgttatg cggaaacgaa aggagaaaaa caattatggg attcaaatca gacattgaaa
    15961 ttgcacagga atgcgaaatg cttccaatta ctcagatcgc agagaaagca ggtattgacg
    16021 acaaatatct ggagcagtac ggaaaataca aagcaaaaat cgactacaat cttctgaaag
    16081 aaagtgataa gaaggacgga aaattaatcc tcgttacagc tatcaaccca actccagcag
    16141 gagaaggtaa aactactact actgtaggtc ttgcagatgg tatgcagaga cttggcaaga
    16201 gtgttatggt agctcttcgt gagccatcct taggaccggt attcggtgta aaaggtggtg
    16261 cagcaggcgg cggatatgca caggttgttc ctatggaaga tattaacctt cacttcacag
    16321 gtgacttcca tgccattggc gcagctaaca acttactggc agctatgatc gataaccata
    16381 tcttccaggg caatgcatta aacatcgacc cacgtaagat cacatggaga agatgtgtag
    16441 atatgaacga ccgtcagctt cgtaacgtag tagatggtct tggcggaaag acaaacggta
    16501 tgcctcgtga agacggatac gacatcacag ttgcatctga aatcatggca gttctctgtc
    16561 ttgcaagcga catcaaagac ctgaaagaaa gattatccaa gatcatcatc ggatatacat
    16621 acggaaaagt ttccgagcag aaacctgtaa cagcaggtga ccttcacgca gaaggcgcta
    16681 tgacagccct gttaaaagat gctctgaaac caaaccttgt acagactctg gaacacgttc
    16741 ctgcaatcgt acatggcgga ccattcgcaa acatcgctca tggatgtaac tctgtaacag
    16801 ctacaaagat ggctatgaag cttgctgatt atgcaatcac agaagctggt tttggtgctg
    16861 accttggtgc tgagaaattc cttgatatca aatgccgtat ggctggttta aaaccaagcg
    16921 cagttgtaat cgtagctaca gtacgtgccc tgaaatacaa cggtggcgtt gctaaagctg
    16981 accttaacaa tgaaaacctg gaagctcttg aaaaaggtat cccgaacctg ttaaaacacg
    17041 tttccaacat caaaaacgta tacaaacttc catgtgttgt tgctatcaac gcattcccta
    17101 cagatacaaa agcagagctt gactttgtag aagctaaatg taaagaactg ggcgttaacg
    17161 ttgctctttc tgaagtgtgg gcaaaaggcg gcgaaggcgg aatcaaactt gcagaagaag
    17221 ttatccgtct tgttgaagaa ccaaacgact tctcctatgc atatgaactg gaaggttcta
    17281 tcgaagacaa actgaaccag atcgttcaga aagtatatgg cggtaagaaa gtagttctga
    17341 cagctaacgc tcagaaacag gcgaaacagt tagaagctct tggctttggc aactgcccga
    17401 tctgtgtagc taagacacag tacagcttaa cagatgacca gactaaactg ggtgctccta
    17461 ctgacttcga agttacagta cgtaacctga agatttccgc tggtgcagga ttcatcgtag
    17521 ctcttacagg cgagatcatg acaatgccag gtcttcctaa agttccggct gctgagagaa
    17581 tcgacgtaga cgagacaggt aagatcacag gtctgttcta atccagttga aatcaatcga
    17641 ataattcaaa aatacaaaaa tcatatttat atatgatatg tgtccagacg attttacagg
    17701 cgggaaaatt ttcccgcctg tttttttctt atttttttat aagataatct tttccggaaa
    17761 taccaggttc cgtcatatgg atcggatcca gaatgcgatt aagttcatcc tcgtccataa
    17821 gcttttcttt cagaatcaga cttcttacag attcgcctgt cttaattgcc ttttttgcaa
    17881 tatccgcagc cttctgatat ccaagatggg ggctgattgc agtgataata cctacactgt
    17941 tttctaccag ataacggcat ctttcttcat ttgccgtaat tcctacaata caattatcca
    18001 ccaatgtctg gactgcatag ccaagagtat cgatagactg gaacatgcaa tagaaaataa
    18061 tcggctcaaa cgcatttaat tccagctgac cagcctctgc agccatggta atggtaacat
    18121 cattaccaat aatattaaaa gcaacctgat tcactacttc aggaataacc ggattaactt
    18181 tacctggcat aatagaggaa ccattctgtt ttgccggaag attaatctcc ccaaaaccag
    18241 tacgtggacc ggaggacatc agacggagat catttgacat tttggaaaga gttaccgcac
    18301 atgctttcac agcaccggaa acggctacaa atggatccag attctgagtg gaatcaatca
    18361 gatcaaaagc ctgtataaag tccattcccg atatttcagt gagatttgga acaattcttc
    18421 tcagatagcc ctcatctgca ttaattcctg ttccgatagc agtacctccc atattaagag
    18481 tccgcatttc atccattgct ttatccattc tgtggatatc acgcatgatt gctaccgaat
    18541 atgccttaaa ttcctgtccc agacgaattg gtactgcatc ctgcatctgt gtacgcccca
    18601 tttttattat gtgatcaaac tctgtagctt tttcattaag agcatcatag aggcgaagaa
    18661 gctgtttttt cagattctgc aacaaacgaa gagaagtcat tttaccggca gtaggaataa
    18721 cgtcattggt agactgtcca caattcacat catcgttagg atttataatt gtataatcgc
    18781 ccttttttcc tcccagtatc tcaatcgcgc gatttgcaat tacttcattg gcattcatat
    18841 ttaaagatgt gccagctcct ccctgaacag gatccacaat aaattcatta tggaattttc
    18901 ctgaaacaat ttcatcacat gcctggacaa tcgcctgtgc ttttttcttc tcaagaagcc
    18961 ccacctcaca attggttatc gctgctgctt tttttatgta tgcaagactg ttaataattt
    19021 ccggatgcat attcagcccc gtaatgtgga aattttcagc cgcacgtaag gattgtactc
    19081 cataatatac atcttccgga atatccttca caccaataga atccctttct acacgatagt
    19141 ctgttttttt catagttatt cgccctccca tgtatttgcc ctcattatat atctctgcta
    19201 taatataatc aaatacatat atttttataa aatatatagt gtttgaatta tatatcggag
    19261 gagtttatat gtttcaggga atggaataca tctatgaggt atacaaggaa aaaagctttt
    19321 ccaaagctgc tgctgctctt ttcatttcgc agccttcttt aagcgccaat gtaaaacgtg
    19381 tggaaaaccg tattggctat cctatttttg atcgaagcac caaaccttta cagttaactg
    19441 aagtcggaaa acattatata caggctgttg aaaaagtcat ggatattgaa aataatctcg
    19501 aaaactacct actggatctg ggaaatctca aaacaggaac tcttaatgta ggtggcagta
    19561 actttttttc ttcgtggatt ctgcctcccc ttattgctga tttttcccaa aaattccccc
    19621 atgttcaaat ttctcttgta gaagaaagta cagcaaagct ctcccagttt ctccaggccg
    19681 gaaagttaga tctggtaatt gataactgca tcctggataa ccagattttt gaacgttata
    19741 tctaccagaa agaacaactt cttctagcgg ttcccaaaaa ttattcagta aataccagac
    19801 tgcagaaata tcagattcct attgaggaaa tccggaacgg gcagttccgt tcttctcata
    19861 ttccttctgt tccattaaac aaattcgaga acgaaccatt tattattctt cgttcagata
    19921 atgataccgg taagcgtgca cttaccattt gtcaggaaaa tcacttttcg ccttctgtag
    19981 tatttcgcct ggatcagcag atgactgcct ataatattgc atgtttggga atgggtatca
    20041 ctttcatcgg ggatcttctg ctctccagag ttccaacaaa ttcagaactt gttttttata
    20101 agctgcccgg tcagagcagt aaacgcactg tgttttttta ctggaagaaa ggccgctata
    20161 tcagcagagc catggaagaa ttcctgaagc tgcccttttc ctgatatgtc ataatcaaat
    20221 aggttatggt gattggtcat catcagatgt acgtcaaaat ggggttgttg tgctaaataa
    20281 gcacaacaac cccagtatgt caggcagata ttcgattaga acaatggctt catcgccgga
    20341 tacagagttc tgaacttctg atatctctct tcatattttg caaccagttc aggatccggt
    20401 tctaccgtat caacaacttt ggcaaatttc ttaccgatgg tttctacatc cgggtaagca
    20461 ccacagccta ctgctgccag catagctcca cccatggacg gtccttcttc gttctccaga
    20521 acatcaacct tcaggttcat aacgtttgca atgatcttct tccacagtgg gctcttagct
    20581 ccaccaccgc agatcttggt tctctcaatc ttgattccaa ggtttcttgc aacttccagg
    20641 gaatcacgaa gaccaaaggc aacaccttcc agaacagcct gtgtcatgtc tgctcttgtg
    20701 ctgtccatgg acattccgaa gaatacacct cttgcatcag gattattatg aggtgaacgt
    20761 tctcccatca aatatggaag gaagaataca tgattctctc ccagcttctg aattggagcc
    20821 tgctctgctg cgaaatcctt tgtctgaaga atctcctctg cccaccattt gttacaggaa
    20881 gctgcgctga gcatgcatcc catcagatga tagcttccat ctgcatgaca gaaagaatga
    20941 agtgcgttat tttcgtccac accaaagttt ttactggaaa taaacacagt tccggatgtt
    21001 ccaagagaaa tattacactg accgtcacca actgtacctg ttcctacagc agctgccgca
    21061 ttgtcacctg cacctgcaac aacttttaca ttctcactga atccaagttc tttcgcaatc
    21121 tcaggtttca gagttcctac tacttcccaa ctctcataca gtttcggaag ctgctcttct
    21181 gtgattccac agatctccaa catttctttt gaccagcagc ggttcttcac atcaagaaga
    21241 agcataccgg aagcatcaga aacatctgta caaaaagaac cggacagacg atatgccaga
    21301 taatccttag gaagcataat ctttactacc ttcttaaagt tctcaggctc atttttctgc
    21361 atccagagga tcttcggtgc tgtgaagcct gcgaaagcaa tatttgctgt atactgtgaa
    21421 agtttgtctt ttccgatcac tgtattcaga tattctgtct cttcgcctgt acgtccgtca
    21481 ttccagagga ttgcaggacg gatcacatta tcatccttgt caagtgttac cagaccatgc
    21541 atctggccgc caaaaccaat tcctgctacc tgcgctctgt cgatatcctt tgtcagctct
    21601 ttcatgcctt ccatactctg cgcaaaccag tcttccggtt tctgctcaga ccagcccgga
    21661 tgtgggaaga ataaaggata ttctctggat acgatgttac agatttttcc tgattcttcc
    21721 ataagaagaa gttttacagc ggaagtacca aggtcaatac caatataata cataagtgct
    21781 ctccttttct atttctaatc taatacatcc cagagcaaag ccccgggatg cctttaatat
    21841 agtgtcagtt tatttattct gtattcagat tcattcactt cacatgaaca ttaataatcc
    21901 gttttactga tttctcatta accccatgga ttttctgtcg ggtatcttac gcctgccggc
    21961 tggttatatc caatcttctt aacatccagt ccaaggaatt tcactacctc atagaatgct
    22021 tttccgtaat gtccaaacat aactgctcca tgatgcggat agttgccctc gatcagtacg
    22081 tgacggtaga atcttcccat ttctttgatt gcgaaaatac cgataccacc gaatgatctt
    22141 gtaggtacat ccagtacttc accttctgca acataagaaa ccagctcgcc ctcggaattg
    22201 cactgtaaac gatagaatgt aatgtcagat gcagcgatat caccttcaag agttcctctt
    22261 gtgaagtctg gttcagatcc tgccggctca agaagtctgt gctggatcag ctgatattta
    22321 acagctctgg aatcacacat cttgcatgca ggagtatttc cacaatggaa tcccataaat
    22381 gtatcagtaa gcttataatc gtattttcct ttaatatctt catcatagat atactgtgga
    22441 acagagttgt tgatatcaag cagtgtaact gcatcattgg aaatgcaaag tccgatgtac
    22501 tcgctgagtg ctccgtagat atcaacctca caggataccg gaattcctct ggaaaccaga
    22561 cggctattta catagcaagg ttcaaatcca aactgtgacg ggaatgcagg ccaacatttg
    22621 tcagcaaatg caacgtattt tcttgctccc ttatgagcct ctgcccagtc aagaagtgta
    22681 agctcaaact gtgccatttt cacattaagg tcagcataat atttgccttc gcccatctct
    22741 tttgccatat ctgcacaaac ttccgggata cgaggatcat tttcatgctc tttgaaagaa
    22801 acaagaagat caagctctga gttctcttca atctcaacac ccagctcata gaggccttta
    22861 ataggtgcgt tgcatgcgaa gaagtcctgt ggacgtggtc cgaaagtaat gatcttaaga
    22921 ttgctgacac cgatgactgc acgtgcaacc ggtacgaaat cagcgatcat ctttgcaata
    22981 tcatctgctg ttccaacagg atattccgga atatatgctt tcagatgacg catttttaag
    23041 ttgtaggagc agttaagcat accacagtaa gcatcacctc tgccgttgat catatcaccg
    23101 tcaccttctg ctgctgctac atacatacaa ggtccgtcaa atctctctgc gatcagagtt
    23161 tcaggagttt caggtccgaa gtttccaagg aaaacaacca gcgcattaca ctctgctttg
    23221 tttacatctt caagagcttt ctccatatc
//
