LOCUS       c00017_gnlPro..        13542 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FHBFGMDF_17.
ACCESSION   c00017_gnlPro..
VERSION     c00017_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 22:55:12
            Original ID  :: gnl|Prokka|FHBFGMDF_17
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 10802
            Orig. end    :: 24344
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13542
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[20802:24342](-)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      complement(10001..13540)
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..13542
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13542
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             complement(171..1502)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg17_8"
                     /sec_met_domain="Amidohydro_1 (E-value: 1.3e-39, bitscore:
                     126.8, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLVIGNGRMITQDASNPFLENGAVAMDGNTIVMVGVTEEVKKVYP
                     DAEFVDAKGGVIMPAFINAHEHIYSSFARGLSINGYNPQGFLDILDGLWWTVDRHLTLE
                     QTKLSAYATYIDSIKNGVTTVFDHHASFGHITGSLNAIEEAAKDLGVRTCLCYEISDRD
                     GMEKSRESVMENVNFIKHALADDSDMIAGMMGMHASFTISDETMALCNELKPEGVGYHI
                     HVAEGIYDLHQCLKEHGKRIVDRLHDWNILGPKTLLGHCIYVNEHEMDLIKDTDTMVVH
                     NPESNMGNACGCPPTMRMVQKGILTGLGTDGYTHDMMESWKVANVLHKHSLCDPNAAWG
                     EVPQMLFEGNAKIANRYFKKQLGVLKEGAAADVIVIDYDPLTPMNESNINGHLMFGVNG
                     SMVQTTVCNGKVLMKDREVLVCDEAKVMADCRQAAKELADDING"
     CDS             complement(1810..2409)
                     /locus_tag="ctg17_9"
                     /transl_table=11
                     /translation="MIKLWLIRHGKTEGNKLSRYIGTTDEPLCQEGTEFLHKMDYPKVQ
                     AVYVSPLKRCVQTAEILFPGEPVHIIEELAECDFGEFENKNYKELEGNPHYQEWIDSNG
                     TLPFPGGESREGFKSRNLRGFDRVVSGCIRSHVAEAALVIHGGTIMNIMEEYADIQKPF
                     YEWHVRNGGGYEVELDENLWKNGRKQLRVNSAIMEG"
     CDS             complement(2402..2782)
                     /locus_tag="ctg17_10"
                     /transl_table=11
                     /translation="MEMIIGGAYQGKTEYARKQYPQLRWSDGGSVTEEELMNAQGVTGF
                     QQYIRSELENGKDVSDLAEKIICKNPDIVLVSQEVGYGVVPVDAFDRKYREAVGRVCTK
                     LAAYSHKVTRVICGIGTVIKDD"
     CDS             complement(2793..3569)
                     /locus_tag="ctg17_11"
                     /transl_table=11
                     /translation="MKSLWNNFKVAFAMFSKIPMPRADWTKGNMKYMFCFFPFIGTVIG
                     GLTMLVAYLGLRFGYQPGFVTAVLVLVPVFVTGGIHVDGLLDTSDALSSWQERSRRLEI
                     LKDSHAGAFAVITATVYFIAWYGAYSQLFNSAENMRAIGILSLGFMVSRCLSGIGVITF
                     PKAKADGTVAEFSRNSSDVLSRNVLIVYLVLLAAGMILIRPVWGSLAFVGALLIFWYYH
                     HIAMKYFGGTTGDISGFFLCICEVGMALILAVVSNF"
     CDS             complement(3615..4157)
                     /locus_tag="ctg17_12"
                     /transl_table=11
                     /translation="MLTLVTGGSGSGKSAFAEDRVLSFGDAQRIYIATMHPFDEESHKR
                     IERHQKMRAGKGFETVECYTGLKNVKLPAGCVVLLECMSNLVANEMFEEQGAHDRTVSE
                     VTKGIENLLEQAAHVVIVTNEIFSDAVVFDGDMDSYLEYLGKINQAAAQRADEVVEVVY
                     GIPVFHKSTDTCSNLCK"
     CDS             complement(4157..5209)
                     /locus_tag="ctg17_13"
                     /transl_table=11
                     /translation="MTLEEAIAKIKPLDHNAMEIAQKRWDSIAKPLHSLGKLETLLIQI
                     AGITGNAEVDLSRRGLIAMCADNGVVEEGVTQTGQEVTAIVAENFLKYDTSVGVMCKQN
                     HAEIFPVDMGMVTDTKVRTDHKIAYGTQNMTKGPAMTREQAVKGLEAGIDMVRELNDKG
                     YRILATGEMGIGNTTTSSAVASVLLKQPVEEMTGRGAGLTSEGLVRKINAIKKAIALNE
                     PDPEDAIDVLAKVGGLDIAGMAGVFLGGAVYGIPVVMDGFISCVSALIAMRICPAARDY
                     ILASHVSKEPAAHLILENMGKEAIIHADMCLGEGTGAVALFPILDLAAAVYHSMSTFDD
                     IHVEQYEELK"
     CDS             5426..5689
                     /locus_tag="ctg17_14"
                     /transl_table=11
                     /translation="MILQCLAFILKNILRIYHIGKQDRQDNRNNIGDIQLHLQLSENEK
                     ADQVHHCGTSAKENIADNGTFIHFSDPLLHKIYPLSPVYFHS"
     CDS             complement(5664..6599)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg17_15"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.1e-27,
                     bitscore: 87.3, seeds: 146, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKLSVVLPAYNEELMVGKTCRVLAEVLTEAKIPYELVVVNDGSG
                     DRTWEEIQKAGERDANVTGVLFSRNFGKEAAIFAGLAQACGDVVAVMDCDLQHPPQTLI
                     EMYRLWQEGYEVIEGVKADRGKEGFLHKECAGFFYDIMSKATKVNMKDASDFKMMDRKA
                     VDSILSMPERNMFFRATSSWVGYKTTSVEFEVQEREAGVSKWSPWSLVKYAFTNIVAFT
                     TFPLQFVTITGAICFICSLVLMVYSLVQYFTGSAVEGYTTLLMVLLLVGSAMMISLGII
                     GYYISKIYEEVKRRPRYIISKVIKNGNIQD"
     CDS             complement(6760..8406)
                     /locus_tag="ctg17_16"
                     /transl_table=11
                     /translation="MMIAYIFVKAYPELFTLTVREKKKIFVMVVAYCVLALFAKAARTQ
                     RNMAGVLVLVLAVFTVTSFGNIFLQGKYMCGLLSALLVVSIMLNVSYQYSYEKDYLSEF
                     AAEEESLDKLESNTDKAVLAAGDSGVYRYDQYGALPYDNTSMYMGTNSTAYYFSLANSS
                     ISDFFSEMYLNTPWEQHYENLDGRTILDRLASVKYFVISGDNFRYLSYGYNKEKGSAGK
                     GKSECRAYENENALPLGYTYDSYIPESEYEKMDVVKKQQALMDGVVLEESTLPEASVDA
                     DNENIQYRMEAGDGCALSKGAIRVTKEGAQLKLVFHGLTDSENYLIADNLDYDSLSPRE
                     LIGNSQWKKMSEYDQNKVLDEDSRWRYWKESKEAAMTVSSNDVTKTIKIFTDKYNAYSG
                     RHDFLCNMGYSRSGVRTMTITFANTGVYTYDKLRVVSQPVQGIEEKTVKLGEEALENVK
                     MGTNEITGDISVSEKKALVLSVPYSKGFTAYVDGKETKLHKANTMFMALELEPGSHEIR
                     LTYCTPYLKAGMFLSVLGLVIYVMLVFRKKK"
     CDS             complement(8369..8593)
                     /locus_tag="ctg17_17"
                     /transl_table=11
                     /translation="VGGCRVFCCCYGGCVCAFFQEEEVPGSEIGIWVVESVLAGAFCRA
                     CAQWFLLCVQQVDLGLWDDDRVYFCEGVS"
     CDS             complement(8804..8920)
                     /locus_tag="ctg17_18"
                     /transl_table=11
                     /translation="MAVYLGDCGFGYVEFLFLLYDLYFYVYLCGFPVFWDFQ"
     CDS             8998..9450
                     /locus_tag="ctg17_19"
                     /transl_table=11
                     /translation="MLHSRINRPSRKNIDQRSHKRRLLRILMIKTKNTKRNPRQINPQK
                     NQNLIQNLRLIRRHKHRQQSQRIPDHIIMQSCKNIRTIPDIHIPHRQFQLMLYKNRMQN
                     LPQIPPIIRQRIQMLRNPVMTPHQRLPIPRKLIINKPRNNPKNQRI"
     CDS             complement(10001..13540)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg17_20"
                     /sec_met_domain="PFOR_II (E-value: 7.6e-20, bitscore: 61.6,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 1.8e-83, bitscore: 270.1,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 2.5e-30, bitscore: 96.2,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 9.4e-14, bitscore:
                     41.9, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 1.1e-11, bitscore: 36.0,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 8e-09, bitscore: 25.9,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.6e-06, bitscore: 18.3,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 5.1e-23, bitscore: 71.2,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="TMARKMKTMDGNHAAAHASYAYSDVAAIYPITPSSVMAEATDEWA
                     TQGRKNIFGQEVQVTEMQSEAGAAGAVHGSLAAGALTTTYTASQGLLLMIPNLYKIAGE
                     QLPAVFNVSARALASHALSIFGDHSDVMACRQTGCAMLCESSVQEVMDLTPVAHLSAIK
                     GKVPFINFFDGFRTSHEIQKIETWDYEDLKDMADMDAIAAFRNHALNPNHPCQRGSAQN
                     PDIFFQAREACNPYYDALPAVVQEYMDKVNAKIGTDYKLFNYYGAADAEHVIVAMGSVN
                     DTIEETIDYLAAAGKKVGVVKVRLYRPFCAQALIDAIPDSVKQITVLDRTKEPGALGEP
                     LYLDVVAALKDSKFDGVKVFSGRYGLGSKDTTPAQIVAVYENTAKEKFTIGIVDDVTNL
                     SLETGAPIVTTPEGTTNCKFWGLGADGTVGANKNSIKIIGDNTDMYAQAYFDYDSKKSG
                     GVTMSHLRFGKKPIKSTYLIHKANFVACHNPSYVNKYNMVQELVDGGTFLLNCAWDMEG
                     LEKHLPGQVKAFIANHNIKFYTIDGVKIGIETGMGPTRINTILQSAFFKLTGIIPEDQA
                     IDLMKAAAKATYGRKGDDVVQKNWAAIDAGAKQVVEIQVPESWKNAEDEGLHMTHATEG
                     RQDVVDFVNNIQAKVNAQEGNSLPVSAFKDYVDGTTPSGAAAYEKRGIAVNVPVWNPEN
                     CIQCNRCSYVCPHAVIRPVALTEEEAANAPEGMKTLPLTGMKEYKFTMAVSALDCTGCG
                     SCVNVCPGKKGAKALAMENLEASADEQKYFDYTVKLPIKEDVIAKFKEATVKGSQFKQP
                     LLEFSGACAGCGETPYAKLITQLFGDRMYIANATGCSSIWGNSSPSTPYTVNAKGQGPA
                     WSNSLFEDNAEFGYGMLLAQRAIRDGLKAKVEDVVANGTNEDVKAAGQEWLDTFAVGAT
                     NGAATDKLVAALEACGCDKAKEILAQKDFLAKKSQWIFGGDGWAYDIGFGGVDHVLASG
                     RDINVMVFDTEVYSNTGGQSSKSTPTGAIAQFAAGGKETKKKDMASIAMSYGYVYVAQI
                     SMGADFNQTVKAIAEAEAYPGPSLIIAYAPCINHGIKKGMAKAQTEEELAVKVGYWHNF
                     RFNPAAEGNKFSLDSKAPSMEDYQAFLDGEVRYNSLKRQNPEKAARLFAKNEAEAKARF
                     EYLQKLIALHSAE"
ORIGIN
        1 ttctaatacc cagttcatta actgttcaaa gggcatacag gtcatgactt cactcataat
       61 ccgatcctcc attatttcat acggtatggc ttctctccat ccgttctata ttttatttac
      121 atttattttt gccaggcaga aaacttatct tttttacaat tctttacaga ttaaccatta
      181 atatcatctg caagttcttt tgcagcctga cggcagtctg ccataacttt tgcctcgtcg
      241 catacaagga cttcgcggtc tttcatcagg actttaccgt tacatacagt agtctggacc
      301 atgcttccgt ttacaccgaa catcagatgt ccgttaatgt tgctttcatt cattggtgtc
      361 agcggatcat aatcgatcac gatcacgtct gctgccgcac cctctttcag gacaccgagc
      421 tgtttcttaa agtatctgtt tgcaatcttt gcatttcctt caaaaagcat ctgtggaact
      481 tctccccagg ctgcgttcgg gtcgcagagg ctgtgtttgt gtaaaacatt tgcaaccttc
      541 caggattcca tcatatcatg agtatatccg tctgtaccaa gacctgtgag gattcccttc
      601 tgtaccattc tcatggttgg aggacatccg catgcattac ccatgttaga ttccgggtta
      661 tgtacaacca tggtatctgt atctttgatc agatccatct catgttcatt cacatagata
      721 cagtgaccga gcaaagtctt cggtccaagg atgttccagt catgaagacg gtcaacaata
      781 cgtttgccat gctctttcag acactgatgg agatcgtaaa tgccttctgc tacatggatg
      841 tgatatccaa caccttccgg ttttagttca ttgcagagag ccattgtctc atcagagatt
      901 gtaaaggatg catgcatacc catcattccg gcgatcatat cactgtcgtc tgcaagtgca
      961 tgcttgataa aattcacgtt ctccattaca gattctctgg atttctccat tccgtcacgg
     1021 tcagaaatct catagcagag gcaggtacgc acacctaaat ccttcgcagc ttcctcgatc
     1081 gcattgaggg aacctgtaat atggccaaag cttgcatggt ggtcaaacac tgtggttaca
     1141 ccattcttga tagaatcaat gtatgtagca tatgcagaaa gctttgtctg ctccagtgtc
     1201 agatgacggt caactgtcca ccataagcca tccagaatat ccagaaatcc ctgaggatta
     1261 tatccgttaa tgcttaagcc tcttgcgaag gagctgtaga tatgctcatg ggcattaata
     1321 aatgccggca tgataacccc acccttcgca tcaacaaatt cagcatccgg ataaactttc
     1381 tttacctctt cagttacccc caccattact atggtgttac catccattgc tacagcacca
     1441 ttctccagga atgggttgga tgcgtcctgt gtgatcattc ttccattacc aattaccagc
     1501 atatagttcc tcctttcact tgtcaaaaac taccaattcg atactgcttt ttaccttttg
     1561 tttaggaatt atgtactaat actgtaacat acttctccga ataatgcaag tagaatttac
     1621 aaaaactttt tggtttttca aatttttttt aggctttatg ccatctccgg tgaacagata
     1681 aaaaaagaac ggggcagtca ttgatgacaa tgaacaacct cgttcttttt ttgattttcc
     1741 tgttttctga tgaagctgat tttatgacaa attttcaggt ttgtcaacaa tttttgtaag
     1801 ataggagagt tatccttcca taatcgcaga attaaccctg agctgttttc gtccattctt
     1861 ccagagattc tcatccagct ccacctcata gccgccgcca tttctcacat gccactcata
     1921 aaatggtttc tgtatatctg catactcttc catgatattc atgatcgtac cgccatggat
     1981 gacaagtgcc gcctctgcca catggctgcg gatacatccg gacacaaccc tgtcaaatcc
     2041 tctcaggttt ctgcttttaa acccttccct gctttctcct cccggaaaag gcagagtacc
     2101 gttgctgtca atccattcct gatagtgcgg attaccttcc agctctttat agttcttatt
     2161 ttcaaattct ccgaaatcgc attctgccag ttcttcaata atatgtaccg gctctcccgg
     2221 aaaaagaatc tctgctgtct gcacacatcg tttcagagga cttacataaa ccgcctgaac
     2281 ctttggataa tccatcttat gcagaaactc tgttccctcc tgacataacg gctcatccgt
     2341 tgtgccgata tatctggaaa gtttattccc ttctgttttt ccatgtctga tcagccataa
     2401 cttaatcatc tttgatcacc gttccgatcc cgcagatcac gcgcgtcacc ttatggctgt
     2461 atgctgccag cttcgtacat acacgcccta cagcctctct gtattttctg tcaaaagcat
     2521 ccacaggtac aaccccgtac cctacttcct gagagacaag gacaatatcc ggattcttac
     2581 agatgatttt ttccgcaaga tctgacacat cttttccatt ctccagttca ctgcggatat
     2641 actgctgaaa accagtcaca ccctgagcat tcatcagttc ctcctctgtg acagaaccgc
     2701 cgtcactcca ccttaactgt ggatactgtt tcctggcata ttcagtcttt ccctgatatg
     2761 caccgccgat tatcatttcc atactcttct cctcaaaaat tagaaaccac cgccaggatc
     2821 aatgccatcc caacttcaca gatacaaaga aaaaatcccg aaatatcccc ggttgtcccg
     2881 ccaaagtact tcatcgcaat atgatgataa taccagaaaa tcagcaaagc tcccacaaaa
     2941 gccagacttc cccatacagg ccggatcaaa atcattcccg cagccagaag caccagatag
     3001 acgatcagca catttctcga gagcacatct gaagaatttc tggaaaactc agcaactgta
     3061 ccgtctgcct ttgctttcgg aaaggtaata actccaatcc ctgacagaca tctggaaacc
     3121 ataaaaccaa ggctcagaat tccgatcgcc ctcatatttt ctgcactgtt aaacaactga
     3181 ctgtaagcgc cgtaccaggc aatgaaatat accgtcgcag taataacggc aaaagcacct
     3241 gcatgggaat ccttaagaat ctccagcctt ctgcttctct cctgccagga actcagggca
     3301 tccgaagtat ccaaaagacc atccacatgg atcccgcctg tcacaaatac aggtaccagc
     3361 accagcactg ctgtcacgaa tcccggctga tacccaaacc gaagtcccag atacgccacc
     3421 agcatagtca gcccgccgat cacagttccg ataaacggaa aaaaacagaa catatacttc
     3481 atatttccct ttgtccagtc agcgcggggc atgggaatct tagaaaacat ggcaaatgcc
     3541 accttaaaat tattccataa agatttcatt gatcaattcc tctttttcat agtatgtcaa
     3601 tcctgtcaaa tgtattattt gcaaagattg ctgcaggtat ctgtggattt gtgaaagact
     3661 ggtatcccat atacaacttc caccacttca tcagctctct gcgcagcagc ctgattgatt
     3721 tttcccagat attccagata agaatccata tctccatcaa acacaaccgc atctgaaaaa
     3781 atctcatttg tgacgatcac cacatgagca gcctgttcca gcagattctc aatccctttt
     3841 gtaacttccg aaactgtccg gtcatgggct ccctgctctt caaacatttc atttgccacc
     3901 agattcgaca tacattccag aagcaccaca catccggcag gcagtttcac atttttgagc
     3961 cctgtatagc actcaactgt ctcgaaacct tttcctgcac gcatcttttg gtgtctctcg
     4021 attcttttat ggctctcttc atcaaaaggg tgcatggtcg ctatgtaaat cctctgtgca
     4081 tctccgaaag aaagcaccct gtcttccgca aaagcggatt ttccgctccc actcccccct
     4141 gtcacaagcg tcagcattat ttcaactcct catactgttc cacatggata tcatcaaaag
     4201 tactcataga atgataaacc gctgctgcca gatcaaggat cgggaataaa gctactgctc
     4261 cggttccctc gcccagacac atatccgcat gaatgattgc ctctttcccc atattctcaa
     4321 ggatcagatg ggcagcaggc tcttttgata catgggatgc aagaatataa tccctcgcag
     4381 ccgggcagat acgcatggcg atcagcgcag aaacacagga aataaatccg tccatgacta
     4441 caggaatacc ataaaccgca cctcccagaa agacacctgc cattccagcg atatcaagac
     4501 cgcctacctt tgccagaaca tcaatggcat cctcaggatc cggttcattt aatgcaatgg
     4561 cttttttgat cgcattgatc ttgcgcacaa gtccctcgct ggtcagacct gcgccgcgcc
     4621 ctgtcatctc ttccaccggc tgtttcagca acacagaagc aactgcactg ctggtggttg
     4681 tatttccgat tcccatttcc cctgttgcca gaatccggta gcccttatca ttcagttccc
     4741 ttaccatgtc aatgcctgct tcaagcccct ttacagcctg ttctcttgtc atggcaggac
     4801 ccttggtcat attctgtgta ccataggcaa ttttatggtc tgtgcggact tttgtgtccg
     4861 tcaccatccc catatccacc ggaaaaatct ccgcatggtt ctgcttacac atcacaccga
     4921 cagatgtgtc atatttcaga aaattctcgg caacgatggc agtaacttcc tgtccggtct
     4981 gtgtcacacc ctcttctacc acgccattat ccgcgcacat ggcgatcaga cctctcctgg
     5041 aaagatccac ctctgcgttt cctgtaattc ccgcgatctg gatcaaaaga gtctccagtt
     5101 ttccaagaga atgcagtggc ttcgcaatac tgtcccatct tttctgtgca atctccatgg
     5161 cattgtgatc taatggctta atctttgcaa tagcttcttc cagagtcatg agttttccct
     5221 ctcttttcct tcattatttt gatttccctg ttgtaaacac aaaaaattta ctgaatacat
     5281 aattcagtat caacacaata aactgtgtca ggaatttccc gatcatatca ttaagcccca
     5341 tcactgacac aagcagccat acaccgccaa cctcgatcac catagtgacc agtctggcac
     5401 tgacaaattt gcagaatggc tgaacatgat ccttcaatgt ctcgcattta tcctgaaaaa
     5461 catacttcga atttaccaca taggcaaaca ggatcgccag gataatcgaa ataatattgg
     5521 cgatattcag ctccaccttc agctttctga gaatgaaaaa gctgaccagg ttcaccattg
     5581 tggtacatcc gccaaagaaa atatagcgga taacggaact ttcatacatt tttctgatcc
     5641 attgcttcat aaaatatatc ctctcagtcc tgtatatttc cattcttaat tacttttgaa
     5701 ataatatatc tcggtctgcg ctttacttct tcataaattt tggaaatata atatccaatg
     5761 atcccaagac tgatcatcat ggcacttccc accagaagca gcaccatcag cagggtggta
     5821 taaccttcca ctgcagaacc tgtaaaatac tgcacaagcg aatagaccat aagtaccagc
     5881 gaacagataa aacatatcgc tcctgtgatc gtaacaaact gtagcggaaa agtagtaaat
     5941 gccactatat ttgtgaacgc atatttcacc aaagaccacg gagaccactt ggaaacgccg
     6001 gcctctctct cctgcacctc aaattccaca ctggtagtct tatatcccac ccaggaagag
     6061 gtagcccgaa agaacatatt cctctcaggc atagacagaa tactgtccac agccttcctg
     6121 tccatcatct taaaatccga ggcatccttc atattcacct tagttgcctt agacatgata
     6181 tcatagaaaa atcctgcaca ttctttatgt aaaaagcctt cttttcctct gtctgccttc
     6241 acgccctcga tcacttcata gccttcctgc cacagcctgt acatctcaat aagtgtctgt
     6301 ggcggatgct gcaggtcaca gtccataaca gccaccacat ctccacaggc ctgcgcaagc
     6361 cctgcgaaaa tcgctgcttc ctttccgaaa tttctggaaa aaagaacgcc tgtcacattc
     6421 gcatccctct ctcctgcctt ctgaatctct tcccatgtcc ggtcgccaga accatcgttt
     6481 acaaccacca gctcataggg aatcttcgct tctgtaagaa cttccgccaa cacccgacag
     6541 gttttcccaa ccatcagctc ctcattatat gccggaagta ccactgataa tttactcatg
     6601 atgtcattcc tcattttgtt tcattcattt acaacagacc aatttctcat tcactgtctg
     6661 ttattcctgt aaatattttc tattttatta tacacaaatt tacaaaaatg tctattctaa
     6721 caaatttatt tcaggctacc tgcaacaatg gaatttggat tactttttct tcctgaacac
     6781 cagcattaca tatataacca accccagaac agaaagaaac attcccgctt tcagataagg
     6841 tgtgcaatat gtcaggcgta tctcatgtga accaggttcc agttccagag ccataaacat
     6901 ggtattcgcc ttatgaagct tcgtttcttt cccgtccaca taagccgtaa atcccttact
     6961 gtacggaaca gacaacacaa gagctttctt ttcggaaaca ctgatatccc ctgtaatctc
     7021 attcgttccc atttttacat tctcgagagc ttcttcaccc agcttcacag ttttttcctc
     7081 aatcccctgc accggctggc tcacaactct taatttatca taggtataaa cacctgtatt
     7141 ggcaaaggtg atcgtcatag tacgaacccc tgatctggaa tatcccatat tgcagagaaa
     7201 atcatgccgt ccactgtagg cattatactt atccgtaaaa atctttatgg tcttggtcac
     7261 atcattggag ctgactgtca tagccgcttc ctttgattcc ttccagtatc gccaccggct
     7321 gtcctcatca agaaccttat tttggtcata ctcagacatc ttcttccact gactgttacc
     7381 aatcagttct ctcggtgaaa gactgtcata atccagatta tctgcgatca ggtaattctc
     7441 actgtccgta agaccatgga acacaagctt cagctgcgcc ccttccttcg tcaccctgat
     7501 tgctccctta gacagagcac aaccatcccc tgcctccata cgatactgga tattctcatt
     7561 atcagcatca acagatgcct caggcagtgt actctcctca agcaccacac cgtccatcag
     7621 agcctgctgc ttttttacca catccatttt ctcatattcc gattcaggaa tataactatc
     7681 ataagtataa cccagaggca gtgcattctc attctcataa gccctgcact cactttttcc
     7741 ctttcctgca gagcccttct ctttattata tccataggaa agatagcgga aattatcacc
     7801 acttatcaca aaatacttca cagaagccag cctgtccagg atcgtccttc cgtccaggtt
     7861 ctcataatgc tgctcccatg gcgtattcag atacatttca ctgaaaaaat cactgatact
     7921 gctgtttgca agactgaaat aataagcagt actgttcgta cccatataca tagaagtatt
     7981 atcatagggc aatgccccat actggtcata acgatagaca cctgaatccc cggcagcaag
     8041 aaccgcctta tccgtattcg actccagctt atccagcgac tcctcttcgg ctgcaaactc
     8101 tgacagataa tccttctcat aagaatactg ataagaaaca ttcaacataa tgctcaccac
     8161 aagcaaagca ctgagaagcc cgcacatata cttcccctgc agaaaaatat ttccaaaaga
     8221 agtaaccgta aacacagcca ataccagaac cagcacacct gccatatttc tctgcgtcct
     8281 tgcagccttc gcaaacagag ccagcacaca ataggccacg accataacaa aaatcttctt
     8341 tttctccctg acagtcagag taaacagctc aggatacgcc ttcacaaaaa tatacgcgat
     8401 catcatccca taagcccaga tccacctgtt ggacacataa gagaaaccat tgagcacatg
     8461 ccctgcaaaa ggcaccagca agaacagatt caacaaccca aatcccaatt tcagatccag
     8521 gtacttcttc ttcctggaaa aaagcacaaa cacacccgcc atagcaacag cagaataccc
     8581 ggcaaccccc cactggatca tattctcccc gatcagatca cccagatact tctcataata
     8641 aattttatca tataaaagcg gcacataatt ctcagcctga aacctgtccg taccaaaaat
     8701 cgtcatgatc accggaagaa aaataaccgc cgcgatcatc aaagccaccg cataatagcc
     8761 gataaacttc accagccatc ccagaacatc cttcacactt ctctcactga aaatcccaaa
     8821 ataccggaaa gccgcataaa taaacataaa aatacaaatc atataaaaga aatagaaatt
     8881 cgacatagcc gaaaccgcag tcgcccagat aaacagccat ggcttctccc tcttataaat
     8941 cttatcaatc cccatcagaa ccagcggcag ataaatcata ggattggaaa aatacggatg
     9001 cttcatagcc gcataaatcg tccatcccgc aaaaatatag atcaacgttc ccataaacgt
     9061 cgcctgcttc ggattcttat gataaaaaca aaaaacacta aaagaaatcc ccgccagata
     9121 aatcctcaga aaaatcagaa cctcatacaa aacctccgtc ttatccgccg gcacaaacac
     9181 agacaacaaa gtcagcggat ccccgatcac ataataatgc aaagttgtaa gaatatccga
     9241 accatacccg atattcatat cccacatagg caattccagc ttatgctcta caaaaatcgt
     9301 atgcagaacc tccctcagat accgcccata atacgccaga gaattcaaat gctgcggaat
     9361 cccgtcatga ctccacacca aagacttccc attccccgca aactgataat aaataaaccc
     9421 cgcaataacc ccaaaaacca gcgtatataa tatatagaaa tccctcttac tatccttact
     9481 cacaaatctc ctcataacaa ctcctatatc tatatcaatc ctctaaaaca ccatgatgat
     9541 tataatcaaa tatctcctcc ttgtcaaaca catccccatc cctttatatc ccagcttctc
     9601 ctctcccttt gcatgcaccc tcactcctcc cttccgtcag acattaagtc tcagtcaaca
     9661 atcagccggg gaatgacaga acatctgacg cgaatctcga gggttcatgt aatttcttag
     9721 tatttggaaa gccgcgttat tcagaaattg ctcactgtct gagcaaagcg agtttgagca
     9781 atttctgaat gcccttagcg gcttttcaaa tacttagaaa ttccatggtt ccgagactga
     9841 gcctcagatg ttctgtcatt ccccggcgtc cccctgttcc aacacataaa aagagccgcg
     9901 atacaaaagt accgcggccc atatatcgtc tggacactat aaatagctct atctatttat
     9961 tttatattat tgtttatcaa tcgttcaaaa accgaaaaga ttattcagca ctatgaagag
    10021 cgatcagctt ctgcagatat tcaaatctag ccttagcctc agcctcattc ttagcaaaca
    10081 gtcttgcagc cttctcagga ttctgacgtt tcagagagtt gtaacgaacc tcaccgtcaa
    10141 ggaatgcctg ataatcttcc atgctcggag ccttggaatc aagagagaac ttgtttcctt
    10201 cagctgcagg attgaatctg aagttatgcc agtatccaac cttaactgct aattcttcct
    10261 ctgtctgagc ttttgccata cctttcttaa taccatggtt gatacatgga gcataagcga
    10321 tgatcagaga tggtcccgga taagcctcag cctctgcaat agcttttaca gtctggttga
    10381 agtcagcacc catggaaatc tgagcaacgt atacatagcc atagctcata gcgatggaag
    10441 ccatatcttt cttcttagtc tctttaccgc ctgcagcgaa ctgagcgata gcacctgtag
    10501 gtgtagactt ggaagactgt ccacctgtgt tagaataaac ctctgtatcg aataccataa
    10561 cgttgatgtc acgtccacta gcgagaacat ggtcaacacc accgaatccg atatcgtaag
    10621 cccatccgtc accaccgaag atccactggg atttcttagc caggaaatct ttctgagcaa
    10681 ggatttcttt tgctttgtcg catccgcaag cttcaagagc agcaacaagt ttgtctgtag
    10741 cagcgccgtt tgtagcacct acagcaaatg tatccagcca ttcctgacca gctgccttaa
    10801 cgtcttcgtt tgttccgtta gcaacaacgt cttcaacttt tgcttttaag ccatcgcgga
    10861 tagctctctg agcaagaagc ataccataac caaactcagc gttatcttcg aacagagagt
    10921 tggaccatgc agggccctgt cccttagcgt ttactgtgta tggtgtagat ggtgaggagt
    10981 taccccagat agaagaacat cctgttgcat ttgcgatgta cattctgtca ccgaacagct
    11041 gagtgatcag tttagcgtat ggtgtttcac cacatcctgc acaagctcct gagaactcaa
    11101 gcagaggctg tttgaactgg ctgcctttaa cagttgcttc tttaaattta gcgataacat
    11161 cttctttgat cggcagttta actgtgtaat caaagtattt ctgctcgtct gcgcttgctt
    11221 caaggttttc catagcgagt gctttcgcac ctttcttacc tgggcaaacg tttacacaag
    11281 aaccacatcc tgtacagtca agtgcagata cagccattgt gaatttatat tctttcatac
    11341 ctgtcagagg taatgtcttc attccttctg gagcgttagc agcttcttct tctgtaagag
    11401 ctaccggacg gataactgcg tgtgggcaga cataagaaca tctgttacac tggatacagt
    11461 tttctgggtt ccatacagga acattaacag cgataccacg tttctcatat gcagctgcac
    11521 ctgatggtgt agtaccatct acataatctt tgaatgcaga tacaggtaag gagttacctt
    11581 cctgagcatt aactttagcc tggatgttgt taacgaaatc aacaacgtcc tgacgtcctt
    11641 ctgttgcatg agtcatatga agaccttcgt cctcagcgtt cttccagctt tccggaacct
    11701 ggatctctac aacctgttta gcaccagcgt cgatagctgc ccagttcttc tgtacgacat
    11761 catcaccttt acgtccgtat gttgccttgg cagcagcttt cataaggtcg attgcctgat
    11821 cttccggaat gattcctgtc agtttgaaga atgcagactg aaggattgtg ttgatacgtg
    11881 ttggtcccat gcctgtttca ataccaatct taacaccgtc gattgtgtag aatttgatat
    11941 tgtggttagc gatgaaagct tttacctgtc ctggtaaatg tttttcaaga ccttccatat
    12001 cccaggcaca gttaaggagg aatgtaccgc catcaacaag ttcctgaacc atgttgtatt
    12061 tgtttacgta ggatggatta tgacatgcta cgaagtttgc tttgtggatc aggtatgtgg
    12121 atttgattgg tttcttaccg aaacgtaagt gggacattgt aacaccaccg gacttcttgg
    12181 agtcataatc aaagtaagcc tgtgcgtaca tgtctgtgtt gtcaccgatg atcttaatgg
    12241 agttcttgtt ggcacctaca gtaccatcag ctcccagacc ccagaattta cagtttgttg
    12301 ttccttcagg agttgttacg atcggagcac ctgtctcaag ggaaaggtta gtaacatcat
    12361 caacgatacc gattgtgaat ttctctttag cagtgttttc ataaacagct acgatctgtg
    12421 caggtgtagt atccttggaa cctaaaccat aacgtccgga gaatactttt acaccgtcaa
    12481 atttgctgtc ttttaatgct gctacaacgt caaggtacag aggctcgcca agtgcacctg
    12541 gctctttagt tctgtcaaga actgtaatct gttttacaga atccggaatt gcatcgatga
    12601 gtgcctgtgc acagaatggt ctgtaaagac gaactttaac aacaccgact ttctttcctg
    12661 ctgctgcaag ataatcgatt gtttcttcga ttgtatcgtt tacagatccc atagcaacga
    12721 ttacatgttc tgcatcagca gctccgtagt agttgaataa tttgtaatct gtaccgatct
    12781 tagcgttaac tttatccatg tattcctgta ctactgccgg aagagcatcg tagtatgggt
    12841 tacatgcttc tcttgcctgg aagaagatat cagggttctg agcagaacct ctctgacatg
    12901 ggtgattcgg attaagagca tggttacgga atgcagcgat tgcatccata tctgccatat
    12961 ccttcagatc ttcataatcc catgtttcaa tcttctgaat ctcgtgagat gtacggaatc
    13021 catcgaagaa gttgatgaac ggaactttac ctttgattgc tgaaaggtga gcaacaggtg
    13081 ttaagtccat aacttcctgt acagaagatt cgcagagcat tgcgcatccg gtctgacgac
    13141 aggccataac gtctgaatga tctccgaaaa ttgaaagtgc atgagaagca agtgcacgtg
    13201 cagatacgtt gaatactgca ggtaactgct caccggcaat tttgtaaagg ttcgggatca
    13261 taagtaacag accctgagat gctgtatatg ttgttgttaa agcacctgct gccagggatc
    13321 cgtgtacagc acctgctgca ccagcctcag actgcatttc agttacctga acttcctgtc
    13381 cgaaaatgtt ctttcttccc tgggttgccc attcatctgt tgcttccgcc ataacagatg
    13441 aaggagtgat cgggtaaata gcagctacat ctgaatatgc ataagaagca tgagcggctg
    13501 catggttacc atccatggtt ttcatctttc ttgccatagt tt
//
