LOCUS       gnlProkkaKOPMNMJB_23   20120 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KOPMNMJB_23.
ACCESSION   gnlProkkaKOPMNMJB_23
VERSION     gnlProkkaKOPMNMJB_23
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-18 10:41:45
            Original ID  :: gnl|Prokka|KOPMNMJB_23
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 20120
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..20120
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[8531:10120]"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      8532..10120
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     cand_cluster    1..20120
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..20120
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /tool="antismash"
     CDS             complement(66..860)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 168.4; E-value:
                     3.5e-51)"
                     /gene_kind="transport"
                     /locus_tag="ctg23_1"
                     /transl_table=11
                     /translation="MLELKNIYKTFNPGTINEKRALNGLNLKLNEGDFVTVIGGNGAGK
                     STMLNAVAGTWPVDEGQILIDNIDVTKLSEHKRATYLGRVFQDPMTGTAATMGIEENLA
                     LAKRRGKSRLLRSGITKAEREEYKELLKILGLGLEDRLTSKVGLLSGGQRQALTLLMAT
                     LQKPKLLLLDEHTAALDPKTAAKVLEITDMIVNRDHLTTLMITHNMKDAIAHGNRLIMM
                     MEGKIILDIQGEEKKKLTVKNLLDQFEKASGEEFSNDSALLG"
     CDS             complement(863..1780)
                     /gene_functions="transport (smcogs)
                     SMCOG1113:inner-membrane translocator (Score: 68.5;
                     E-value: 8.4e-21)"
                     /gene_kind="transport"
                     /locus_tag="ctg23_2"
                     /transl_table=11
                     /translation="MQIITLITALPGAVAQGLIWGIMAIGVYITFRILDIADLTVDGTM
                     CTGGAVCIMMMLSGHNVWISMLAATLAGMLAGLVTGIFHTFMGIPAILAGILTQLSLYS
                     VNLKIMGKANQAINVDKYNLLVSLRHIKNASLSQNTIFIVAVMCVLLIAILYWFFGTEL
                     GCSLRATGCNPNMSRAQGINTNRNKVLGLMISNGLVGLSSALLAQYQGFADVNMGRGSI
                     VIGLAAVIIGEAIFGRIFRNFALRLLAVIFGSILYYLVLQIVIWMGIDTDLLKMLSAIV
                     VALFLAFPYWKGKYFNKPAKRGGK"
     CDS             complement(1931..2995)
                     /locus_tag="ctg23_3"
                     /transl_table=11
                     /translation="MKRKTLAIALAAAMAMGTCAVTASAADGDKYTIGICQLVQHEALD
                     AATQGFKDEVTKELGKDAVTFDEQNAQGDSNTCSTIINSFVSNNVDLILANATPALQAA
                     AAGTSDIPILGTSVTEYGVALGLDDFDGTVGGNISGTADLAPLDQQAAMLNELFPDAKN
                     VGLLYCSAEANSQYQVDTVKAELEKLGYTCEYYAFSDSNDLSSVVTTAADASDVIYVPT
                     DNTVASNTEIINNICLPAKVPVITGEEGICSGCGVATLSISYYDLGVTTGKMAVKILKD
                     GEDISTMPIEYAPNYTKEYNKDICKELGIEVPDDYVAIGEAAEDTEEASDDAEASDKSS
                     DETSEDNTTEEAAR"
     CDS             3259..4023
                     /locus_tag="ctg23_4"
                     /transl_table=11
                     /translation="MAYSIMLDAGHGGQDPGAVYKGRQEKNDNLKLALAVGEILKNKGI
                     DISYTRTGDVYQTPFEKAQLANQAGVDYFISFHRNSSPKENQYNGAEVLIYDKSGIKYQ
                     MAENILGALGEVGFCEIGVKERPGLVVLRRTRMPALLIETGFINSEEDNKLFDNKFSDI
                     AQGIADAILGSLDEETVQEPLYYRVQTGAFRKKENADRMLYQLLEKGYPSFMLHETGLY
                     KVQTGAYQQIGNAVNMEQRLRDDGYSTVIVTK"
     CDS             4264..4917
                     /locus_tag="ctg23_5"
                     /transl_table=11
                     /translation="MHYLRGAVEKTDNEELVMMNDVYEKFLKSSEEFIFAENKPEKSDI
                     IFVPGNSYPQMAEKAAELFKKGMADWILPSGKYSVVNGKFSGVLEKSNVYDKEYGTEWE
                     FLRDVLIKNGVPDQKILKEDQATFTYENAIYSRQVTDHAGLEIERAILCCKSYHARRCL
                     MYYQLLYPETEFYVVPVNADGITRENWRKNEEGIDAITGELSRIVKQFSLMLER"
     CDS             complement(4921..6204)
                     /gene_functions="other (smcogs) SMCOG1273:hypothetical
                     protein (Score: 355.5; E-value: 7.2e-108)"
                     /gene_kind="other"
                     /locus_tag="ctg23_6"
                     /transl_table=11
                     /translation="MDSSIAFQAVAILILIALSSFFSSAETAMTTVNKIRIQSLAEQGN
                     KRAVILEKIISDSPKMLSTVLIGNNIVNMSVSSLMTTLTIKILGNAYVGIATGILTLLI
                     LIFGEITPKNLATIHAEKLSLAYSRIIYGLMILLTPVVFIVNKITEGVLVILHVNPDEK
                     ANAMTEHELRTLVNVGEKDGVIENEEKQMIYNVFDFGDSTAKDVMIPRIDMTFIDINFS
                     YDELMAVFNEDMHTRFPVYEDNTDNVIGIINMKDLLVYPKDKPFSIRNILREPYFTYEY
                     KATADLMIEMRKASVNLAIVLDEYGATAGLVTLEDLLEEIVGEIRDEYDEDEVEDIKEI
                     QPEREYVVQGSAKLDDINEALHINLESEDYDSIGGYIIEQLDCLPKEGQSVTLESGIRL
                     VVDRLDKNRIELVHIWLPEKKTETEEQP"
     CDS             6550..8058
                     /locus_tag="ctg23_7"
                     /transl_table=11
                     /translation="MSNNITRIRKNKLKGTGIFAAAALTAALIAGNNVPGVIRQVSAAE
                     SQENTVSSLIPDNITLDKPVELANVELPATEYGTFEWADGSFVPAQRVQSCEVLLIPAE
                     GQDLSHVDGWDPESGAVVGYINVIVNSITDGDNSDKTEGSDKTDPTENADPTETPETSS
                     EKPAADENADTDNKEDKESKSDQDNKTDTDNEENKIEEDKTDNKNNKDNNSNADKTDKD
                     TETTGKLEPADDMTQDKEDTKKDDEDGADDNIFDNPVLPDDKDDRPTDAEESLSDEEKE
                     ERAALNHTCDGITVSGVNLPWYVQFRVSSGDSYQFTNESDAMIFQSYEFELWDLKNNTE
                     YEIPNGDYISVTVPVKSGYQYTIEHLLDNGATETIVPSVENGIMVFSTHSFSPFGIAGS
                     RQLVGPDTGNDTDDTDAVTPAPASSDSQSSDSGKNNTVSMNDSSDSNNGSSSDQNDNST
                     ENKAVKNNNTVNTGDTTSIMPFVILFVAAAVIAGVVVFIKKRKK"
     CDS             8108..8458
                     /locus_tag="ctg23_8"
                     /transl_table=11
                     /translation="MKVRAILKSLLFAYALTGVALLLLALVLFAFDLGETAVDAGIIII
                     YVLACFMGGFMAGRIVRKDKYLWGVITGLTYYVLLLTVSVMAKGGWDMSAAHAVTTFFM
                     CTGGGTLGGMLS"
     CDS             8532..8672
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SCIFF"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR03973"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg23_9"
                     /sec_met_domain="TIGR03973 (E-value: 1.1e-27, bitscore:
                     87.3, seeds: 29, tool: rule-based-clusters)"
                     /sec_met_domain="SCIFF (E-value: 1.4e-27, bitscore: 87.0,
                     seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEHIKTLNTKNLQNTVKKGGCGECQTSCQSACKTSCTVGNQSCEQ
                     K"
     CDS             8753..10120
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Ranthipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg23_10"
                     /sec_met_domain="Ranthipeptide_rSAM_RRE (E-value: 1.8e-29,
                     bitscore: 93.5, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 3.1e-16, bitscore: 51.5,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 3.1e-14, bitscore: 45.3,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 6.9e-20, bitscore:
                     62.9, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLIHRYKSNGFNIVLDINSGCIHLVDEVTYEVLPYLEKGLDTEA
                     IAEKLENKYNREDIETSVKECNKLKEDGMLFTKDVYENAIEEFSNNRQTVVKALCLHIA
                     HDCNLACRYCFAEEGEYHGRRALMSYEVGKKALDFLIANSGSRKNLEVDFFGGEPLMNW
                     QVVKDLVKYGREQEKLHNKKFRFTLTTNGVLLNDEVMEFCNKEMGNVVLSVDGRKEVHD
                     YMRPFRKGAGSYDLIMPKFQKFAESRNQDKYYVRGTFTHHNLDFSKDVLHLADLGFKQI
                     SVEPVVAADTEEYAIREEDIPQIMEEYDTLAKEMIKREKEGKGFNFFHFMIDLTGGPCV
                     YKRLSGCGSGTEYLAVTPWGDFYPCHQFVGEEQYLMGNVNEGITKPEIQKEFGGCNVYT
                     KKDCKDCFARFYCSGGCAANAFHFQGDIKGNYEIGCELQRKRVECAIMIKAALACD"
     CDS             10232..12640
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1035:MMPL domain-containing transport protein (Score:
                     38.5; E-value: 6.5e-12)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg23_11"
                     /transl_table=11
                     /translation="MKKSKGIVVLLLTLILTVFFCFTAAVGIGPTGTGAAKHINTGLDL
                     AGGVSITYQAKESNPTSEEMSDTIYKLQKRVEQYSTEAQVYQEGSDRITVEIPGVTDAD
                     TILNDLGKPGSLYFITKEDADGNQNFTTGQDGYVLSRTMDEIKESGSVVLEGSDVADAQ
                     GGAIQNQGTSGKEYVVSLTLTSDGENSGKTKFAEATKNNVGKQIAIVYDNNIISAPNVN
                     EEISGGKAQISGMSDLEEAQNLASYIRIGSLGLELEELRSSVVAAQLGEEAISTSVLAG
                     AIGLIIVIIFMIIVYRVPGVVAGIALILYTSLMLITLNAFDITLTLPGIAGIILGIGMA
                     VDANVIIYARIREEIGAGVSVRNSIKSGFSKAFSAIFDGNITTLIAAFVLMWLGSGTVK
                     GFAYTLALGIVISMFTALVVSRLVVNALYAVGVRDPKFYGSAKERKAVDFIGKKKVFFI
                     ISIILILCGPAAMFANSHAGNKALNYSLEFSGGTSTTVTFNEDMDIKTIDSEVTPVVEK
                     VTGDKNVQPTKVVGTNQVVIKTRSLNQSEREALQSALVEKFGVDDSTISTESISSTVSS
                     EMRRDAIVAVIVATICMLLYIWFRFKDIRFASSAVLALLHDVLVVLAFYALARVSVGNT
                     FIACMLTIVGYSINATIVIFDRIRENLHSSSREKLAEVVNTSITQTLTRSIYTSFTTFV
                     MVAVLYIMGVSSIREFAAPLMVGVLIGAYSSVCITGALWYVMKKKFTGKGQPAIAAAST
                     STKSSSKPKKTRDVSQKDPTQPKKKNRKRVAERLAAEESAKKQQNDDAE"
     CDS             12757..14469
                     /locus_tag="ctg23_12"
                     /transl_table=11
                     /translation="MEKWVIAAKRADFNQIGQQFHIDPVIARVIRNRDVIGEDKIREYL
                     SGTVQELPSPWLMKDMEKAVDILERKISQKAKIRIIGDYDIDGVTSTYILMKGLARIGA
                     DVDTYIPDRVSDGYGIHAHLIERAETDRIDTIVTCDNGIAAAAEIQMAKDKKMTVIVTD
                     HHEIPYREEKGERRMVLPPADAILNPKQYDCPYPNKNLCGAVVAFKYITVLYERFGVPA
                     EELEDYYELAAIATVGDVMDLQGENRILVKEGLCRLKNTKNKGLQELIRANSLEDAKIT
                     AYHIGFVLGPCINASGRLDTAARSLALLNAKTKEEAARLAGDLTALNQSRKALTEKGKE
                     EAIRIIETTELKNDRVLVVYLPDCHESLAGIIAGRIREKYHKPAFVLTGGETSAKGSGR
                     SIESYSMYEELIKCADLMIQFGGHPMAAGLSIEEKNIEEFRRRLNVNCTLTDEELRPKV
                     VIDVPMPVSYVTKELVEQISLLEPFGKGNTKPVFAQKNLRVLDHSIIGKNKNAVKLKLL
                     DPQGISVEGIYFGEAEEFVNFIREKDSVSVTYYPEINRFRGRESLQIIIQNYC"
     CDS             14617..15141
                     /locus_tag="ctg23_13"
                     /transl_table=11
                     /translation="MKKIEDYVLSIPDFPEPGIIFRDITSVLQDADGLQLAIDSMQDCL
                     KDVDVDVIAGTESRGFIFGVPIAYNLHKPFVPIRKKGKLPRETVSVSYDLEYGSAEIEM
                     HKDSIKPGQKVVIVDDLIATGGTIEAAIKLVEQLGGEVVKVVFLMELAGLKGRERLNGY
                     DVASVICYDGK"
     CDS             15179..17509
                     /locus_tag="ctg23_14"
                     /transl_table=11
                     /translation="MTEITRSTEAKKDEMQIEKEKLESVKRADAAVKTMHDFTSPEVLY
                     KELINSVLKYHPSTDISMIEKAYKVASEAHEGQKRKSGEPYIIHPLCVAIILADLELDK
                     ETIVAGLLHDAVEDTWMTYEEVEKEFGSEVALLVDGVTKLGQLSYSADKVEVQAENLRK
                     MFLAMAKDIRVILIKLADRLHNMRTLQYMRPEKQQEKARETMDIYAPIAMRLGISKIKV
                     ELDDLSLKYLKPDVYYDLVQKVALRKSEREQFVGAIVKEVKKHMDDANIKAQVDGRVKH
                     FFSIYKKMVNQDKTIDQIYDLFAVRILVDTVKDCYAALGVIHEMYKPIPGRFKDYIAMP
                     KPNMYQSLHTTLIGPNGQPFEIQIRTYEMHRTAEYGIAAHWKYKESSDGKVPVGKSEEE
                     KLNWLRQILEWQRDMSDNKEFMSLLKNDLDLFADSVYCFTPQGDVKTLPSGSTPVDFAY
                     SVHSAVGNKMVGARVNGKLVPIEYEIKNGDRIEIITSQNSQGPSRDWLKLVKSTQAKNK
                     INQWFKKELKEDNILKGKEMLAQYARAKGFKITNYTKTQYLEAVLRKYGFRDWDSVLAA
                     IGHGGLKEGQVFNKLVEAYDKENKKNLTDEQVLEAASETQEKLHIAKSKSGIVVKGIHD
                     VAVRFSKCCNPIPGDEIVGFVTRGRGITIHRTDCVNVLNMSETDRTRLIEAEWQQPDTK
                     EKEKYMAEIQVYANNRTGLLVDLSKIFTERKIDLRSINSRTSKQEKATISMSFEIGSKE
                     ELRSLIEKIRQVESVIDVERTTG"
     CDS             17574..18203
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1170:metallo-beta-lactamase family protein (Score:
                     159.8; E-value: 9.5e-49)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg23_15"
                     /transl_table=11
                     /translation="MKNLELQKCILGPVYTNCYLLKNKETGELIIVDPADCPEKIELKI
                     SRMSGKPVAILLTHGHFDHILAAQAVKEKYNIPIYACRQEEEMLREPSINMTVHYGRGC
                     SIVPDVFLEDLDVIRMAGFSVQMIHTPGHTKGSCCYYLKDEGVLFSGDTVFYGSVGRTD
                     FPGGSTAEIVKSLHKLVDSLPEETEVFPGHDASTTIGYEKRYNPFV"
     CDS             18196..19710
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg23_16"
                     /sec_met_domain="PF04055 (E-value: 4.8e-25, bitscore: 80.4,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCKIGILFENRDFEHDVYELIKAFYPEAEIHTLYENAEAEYDLRF
                     SVERDNDSYIIKYERAENLSKQETEQKGVISADILAKENAGCGIQDAHALRKENKDTIK
                     YALYQLLVKLTGRTLPWGNLTGIRPAKLAMGMIESGMKNTEAAREMRERYLVSPQKTAL
                     AITIANREREILKDIDYENGYSLYIGIPFCPSICLYCSFSSYPLKVWEKRTDEYVEALC
                     REVRETALMMKGRKLDTIYIGGGTPTTLLPHQIRKLLDTVGEAFGYEGLAEFTVEAGRP
                     DSITREKLMTIREYPVTRISVNPQTMNQETLDIIGRRHTVEQTKEAFRLARELGYDNIN
                     MDLIVGLPGEDIHMVERTLEQIRELAPDSITVHSLAVKRAARLNIFKEKYQEMSFENNQ
                     EIMDLTMKTAYEMGMGPYYLYRQKNMKGNFENVGYAKVDKAGIYNILIMEEKQPIIALG
                     AGGSSKLVFDHGQRIERVENVKDVSNYISRIDEMIERKRTAIATWL"
ORIGIN
        1 ttcttaccaa aaaggagtta ttttttacca aaaacacaaa ctattttaca ctaccattta
       61 tacggttatc cgagcagtgc agagtcatta ctgaactctt ctccgcttgc tttttcaaac
      121 tgatccagaa ggtttttaac tgtcagtttt ttcttttctt ctccctggat atccagaatg
      181 atttttcctt ccatcatcat gatcagacga ttgccatgtg caatagcgtc cttcatgttg
      241 tgggtgatca tcaatgtcgt aaggtgatcg cggtttacga tcatatctgt aatttccaga
      301 actttggcag ctgtttttgg atcaagagct gcggtatgtt cgtccagaag cagaagcttt
      361 ggtttctgaa gcgttgccat cagaagagta agagcctgtc tctgaccacc cgagagaagt
      421 cctactttag aagtcagtct gtcttccaga ccaagaccaa gaattttcag gagctctttg
      481 tattcttcgc gctcagcttt agtgattccg gagcggagaa gacgggattt tccgcggcgt
      541 tttgcaagtg caaggttttc ctcgataccc attgttgcag cggttcctgt cattggatcc
      601 tgaaacacac gtccaaggta tgtagcacgt ttatgttcag aaagttttgt aacatcaata
      661 ttatcgataa gaatctgtcc ttcatcaacc ggccaggttc ctgcaacagc atttagcata
      721 gtagatttgc cggcgccgtt tcctccgata acagttacaa aatcgccttc gttcagcttc
      781 aggttcagac catttaatgc acgtttctca ttaatggttc cgggattaaa ggttttatag
      841 atatttttaa gttcaagcat ttttatttac ctcccctttt ggctggttta ttaaagtatt
      901 tgcctttcca gtatgggaat gcaaggaaga gagcaactac gattgcggac agcatcttca
      961 gcaggtcagt gtcgataccc atccagataa caatctgaag taccagataa tacagaatgg
     1021 aaccgaagat aactgctaac aagcgaaggg caaagttgcg gaaaatacgt ccaaagattg
     1081 cctcgccaat aataactgct gccagaccga taacgatgga accacgtccc atgttgacat
     1141 ctgcaaatcc ctgatactgt gcaaggagtg cactggaaag tcctaccaga ccgttggaaa
     1201 tcataagtcc gagaacttta ttcctgtttg tgttgatacc ctgggcgcgt gacatatttg
     1261 ggttgcatcc ggttgcacga agggaacagc caagctctgt tccaaaaaac cagtagagaa
     1321 tggcaatcag gagaacacac ataactgcta caataaaaat tgtgttttgg gaaagagatg
     1381 cattttttat atgtcgcagg gaaaccagaa gattatattt atcaacgttg attgcctgat
     1441 ttgcttttcc catgatcttc aggtttacgg aatacagaga taactgtgtc aggattccgg
     1501 caaggattgc gggaattccc ataaaggtat gaaaaattcc ggttacaagg cctgccagca
     1561 ttccggcgag agtagcggcc aacatggaaa tccagacatt atgaccggaa agcatcatca
     1621 taatacacac tgcaccaccg gtgcacatgg tgccatcaac tgtaaggtct gcaatatcca
     1681 gaatgcggaa agtgatataa acaccgattg ccataattcc ccagatcaga ccctgggcta
     1741 ctgcacccgg aagtgcagtg attaatgtta taatttgcat ttgtaatttc ctcctgttga
     1801 gacgcgaaaa gcgagagagg cgtcaaacct ttcccgctga tcgcatataa attgaatttt
     1861 ttataactgt ttgataagct gttactcaaa atcctgttgc tgtgagtatt tttcaactgt
     1921 ctgaccggat ttatctggca gcttcttcag ttgtgttatc ttctgatgtt tcatcagaag
     1981 atttgtctga tgcctctgca tcatcagaag cctcttctgt gtcttcagca gcctcaccga
     2041 ttgcaacata atcatccgga acttcgatgc ccagctcttt gcagatatct ttgttatatt
     2101 cttttgtgta gtttggtgca tattcgatcg gcattgtgga aatatcttca ccgtctttta
     2161 aaatcttaac agccatctta ccggttgtaa caccaaggtc ataatagctg atggaaagtg
     2221 ttgcaacacc acatccgctg cagatacctt cttcacctgt gattaccgga acttttgccg
     2281 gaaggcagat gttgttgata atctctgtgt tggaagcaac tgtattatct gttggtacat
     2341 aaattacatc acttgcgtca gcagcggttg taacaacaga agagagatca ttagaatcag
     2401 agaatgcata gtattcacat gtatatccga gtttttcaag ttcagctttt actgtatcta
     2461 cctgatactg agagtttgcc tcggcagaac agtagagaag acctacattt tttgcatccg
     2521 ggaaaagttc attgagcatt gctgcctgct gatcaagggg agcaaggtct gcagttccgg
     2581 aaatatttcc gcccacagtt ccgtcgaaat catccagtcc aagtgcaaca ccgtattcag
     2641 taacagaagt accaagaatc ggaatatcgc ttgttcctgc tgcagctgcc tgaagagcag
     2701 gagttgcatt tgcaagaatc aggtcaacat tattggaaac gaagctgtta atgattgtag
     2761 aacaggtgtt ggaatctccc tgtgcgttct gctcgtcaaa ggtaacggca tcctttccca
     2821 gttctttggt gacttcatcc ttgaatccct gtgtcgcagc gtcgagagct tcgtgctgta
     2881 caagctgaca gataccaatt gtatatttgt ctccgtcagc agcacttgct gttactgcgc
     2941 aggttcccat agccatggct gctgcaagag cgattgctaa tgtttttctt ttcataatga
     3001 tatatcctcc taatataatg tttaaattaa gtcaggtaag aattgcgttt attatttgat
     3061 aatatgaaac ttacctgaat ccgaatgatt ttctgcaggg aaagcagtac tggtaaatga
     3121 ttcggataat gtcatcgggt tatctgacta tgacgtttta aagtataacg ctttagtgcg
     3181 aaaaagtcaa gcgacctgca caattatatt tttaattcat atagtataaa gagtatatga
     3241 agaaagcaga gtgtcgtcat ggcatattcg attatgctgg atgccggaca tggaggtcag
     3301 gatccgggag ccgtatataa gggaagacag gaaaagaatg acaatcttaa acttgctctt
     3361 gcggtaggtg agattttaaa aaataaaggg attgacatct cttatacccg taccggtgat
     3421 gtctatcaga cgccttttga gaaggcacag cttgcaaatc aggcaggagt agattacttt
     3481 atttcatttc accgaaacag cagcccaaag gaaaatcagt ataatggagc ggaagttctg
     3541 atttatgata aaagtgggat taaatatcag atggctgaga atattctggg agctctggga
     3601 gaagtgggat tttgcgaaat cggtgtaaaa gagcggccgg gacttgtggt cctcagacga
     3661 accaggatgc cggctctttt aatagaaacc ggatttatca attccgaaga agataataaa
     3721 ctgttcgata acaagtttag cgatatagct cagggaattg cagatgcgat tcttggaagc
     3781 ctggatgagg aaacagtgca ggaaccgctt tattacagag tgcagactgg agcgttcaga
     3841 aaaaaagaga atgcggaccg tatgttatat cagttactgg aaaaaggtta tccctctttt
     3901 atgttacatg aaaccggatt gtataaagtt cagacaggtg cctatcagca gattggtaat
     3961 gcggtaaata tggagcagag actgagggat gatggttaca gtacggttat tgtgacaaaa
     4021 tagccttctg gaaatattgg aagtctgcgg attttttgtt taaccgaatc aaataagtcc
     4081 cctgcggagg ttgcgaaaag caataagtag tgggggacat agttttaaga attaacttgg
     4141 ttgtacttta acagaaaaaa tatggtacac tgtatctgtc tatagaaatc ccatagaaat
     4201 cctcgtaaat aatgcatatt gttccggctc atcagaacgt aaaattctgt tggactgtct
     4261 caaatgcatt atttgagagg tgctgtagaa aaaacagata acgaggagtt agtaatgatg
     4321 aatgacgtat atgaaaaatt tttaaaaagt tcagaagagt ttatttttgc agaaaacaag
     4381 ccggaaaaat ctgatattat ttttgttccc ggaaatagtt atccgcagat ggcggaaaaa
     4441 gcagcagaat tgtttaagaa agggatggcg gactggattc tgcccagtgg aaaatacagc
     4501 gtagtaaatg gaaagttttc aggcgttctt gaaaaaagca atgtatatga taaagaatat
     4561 ggaacagaat gggaatttct cagggatgtt cttataaaaa acggagttcc ggatcagaaa
     4621 atcctgaaag aagatcaggc aacctttact tatgagaatg caatttattc cagacaggtg
     4681 acagatcatg cgggactgga aatagaaaga gcgattttgt gctgcaaatc ttaccatgca
     4741 agaagatgtc tgatgtatta tcagcttttg tatccggaaa cagaatttta tgtggtgcct
     4801 gtgaatgcag atggaattac cagagaaaac tggagaaaga acgaagaagg aattgatgcg
     4861 attacaggag aactctccag aatcgtgaaa caattttcac tgatgctgga gagatgacag
     4921 ttacggctgt tcttctgttt cggttttctt ctcgggaagc cagatgtgga caagttcgat
     4981 tctgtttttg tccagacggt caacaaccag gcggatgcca ctttcaagtg tgacagactg
     5041 accctctttg ggaaggcagt caagctgttc aataatatat ccgccgatag aatcataatc
     5101 ttcagattcc agattaatat ggagggcttc gttgatatca tccagcttgg cagaaccctg
     5161 aacaacatat tctctttcag gctggatttc tttaatatct tcgacttcat cctcatcgta
     5221 ttcgtcgcga atctcaccta cgatctcttc caacagatct tccaatgtga ccagaccggc
     5281 tgtggcaccg tattcgtcca gaacgattgc cagattgacg gatgctttac gcatttcaat
     5341 catcaggtct gctgtagctt tgtattcata ggtaaaataa ggctcacgca ggatgttgcg
     5401 gattgaaaaa ggtttgtcct ttggataaac aagaagatct ttcatattga taataccgat
     5461 tacgttatca gtgttgtcct cataaaccgg aaaacgggta tgcatatctt cattgaagac
     5521 cgccataagt tcatcatagg aaaaattgat atctataaag gtcatgtcga ttctgggaat
     5581 catgacatct tttgcagttg aatcgccaaa atcaaacaca ttgtagatca tctgtttttc
     5641 ttcgttttca atgacgccgt ctttttcacc tacattgacg agggtacgca gttcatgttc
     5701 agtcatggca tttgcctttt cgtccgggtt aacatgcaga atgaccagta caccttctgt
     5761 tattttattt acaataaaaa caacgggagt aaggagaatc ataagtccgt atattattct
     5821 tgaataggcc agggacaatt tctctgcatg gattgttgcc aggttttttg gggttatctc
     5881 gccaaaaata agaatcaaca gagtcagaat gccggttgcg attcctacat atgcgtttcc
     5941 cagaatcttt atggtgagtg tagtcatgag agaagaaaca gacatattta caatgttgtt
     6001 tccgattaat acggtactga gcatctttgg agaatcggaa attatttttt ccagaataac
     6061 agcacgtttg ttgccctgct cggcaagaga ctgtatccga attttattta cggttgtcat
     6121 agcggtttcc gcagaagaaa aaaatgaaga aagtgcgatc agtatcagaa tcgccaccgc
     6181 ctgaaaggca atacttgaat ccaagattta ttcactcctt ttgattattt ttttattgat
     6241 tgaatcatat cataaaacat ttaagcaaaa tatacatgat ttcatataaa aaatcaagaa
     6301 aaagcttttg gttcaaagat agtataaaaa aatttaaaag aggactgtcg aaaaagtaag
     6361 atttgtgtta taattcactc gattaaaatg aaaaaaaaca ttacagaata tttacaaaat
     6421 gataaaagtt tgataatata cagatatgta atattattgt attacgtaaa aaagaactga
     6481 tatttggctg aaagtaaaaa aataattatc aggaaacata aaaatcgaat ataaatatag
     6541 aggtgcgata tgtccaataa tataactaga ataagaaaaa ataaattaaa aggaacgggt
     6601 atttttgcgg cagcggcttt aacggcggct ttgattgcag gaaataatgt accgggtgta
     6661 ataagacagg tcagtgcggc tgagtcacag gagaatactg tatcttctct gattccggat
     6721 aacatcacgc ttgataagcc tgtagaactt gcgaatgtag aacttccggc aacggaatat
     6781 ggaacttttg aatgggcgga tggaagtttc gttcctgcac agcgtgtaca gagctgtgag
     6841 gtacttctta taccggcaga aggacaggat ttaagccatg tggatggatg ggatccggag
     6901 agcggcgcgg ttgtcggtta catcaatgta atagtgaaca gtattacgga tggtgataat
     6961 tctgataaga cagaaggctc agataaaaca gatccaacag aaaatgcaga tccaacagaa
     7021 acgcctgaaa cttcgtcaga aaaacctgcc gcagatgaaa atgctgatac agacaataaa
     7081 gaagataagg aaagtaaatc agatcaggat aataaaactg atacagacaa tgaagagaat
     7141 aagattgaag aagataaaac agataataaa aacaacaaag ataataacag caatgcagat
     7201 aagacggata aagatacaga aactaccggt aagctggaac ctgcagatga tatgacacag
     7261 gataaagaag atacgaagaa agatgatgaa gatggcgcag atgataatat ctttgataat
     7321 cctgttctgc cggacgataa ggatgaccgt cctacagatg cagaggagtc tctttctgat
     7381 gaagaaaaag aagagagggc cgcacttaat catacctgcg acggtattac agtaagcgga
     7441 gttaatcttc catggtatgt acagttcaga gtttcaagcg gtgacagcta tcagtttacc
     7501 aatgaatcag atgcaatgat tttccagtct tatgaatttg aactctggga tcttaagaat
     7561 aatacagaat atgagattcc taatggagat tatatcagtg tcactgtgcc ggtaaaatcc
     7621 ggatatcagt atactatcga acatctcctg gataacgggg caactgagac gattgttccg
     7681 agtgtagaga atggtattat ggtattcagc acacattctt tcagcccatt tggaattgca
     7741 ggaagcagac aattggtagg gcctgataca ggaaatgata cggacgacac agatgcggta
     7801 actcctgcac cggcttcctc cgacagtcag agttctgatt ccggaaagaa caatacagta
     7861 tctatgaatg acagttctga cagcaataat ggttcttctt ctgatcagaa tgataattca
     7921 acggaaaata aagctgtgaa aaataacaat acagtaaata ccggagatac aacatcaatt
     7981 atgccgtttg tgatactgtt tgtggcagct gcagtgatcg ccggtgtggt tgtatttata
     8041 aaaaagagaa agaaatagaa gaataacact gattcctccc ccatatagtt taacaggagg
     8101 ggaagcaatg aaagtcagag caattttgaa atcactatta tttgcatatg cattaacagg
     8161 agtggcatta ctgcttttgg ccctggtact gtttgctttt gatctgggag aaacagctgt
     8221 agatgcaggg attatcataa tttatgtact tgcatgtttc atgggaggtt ttatggcagg
     8281 cagaattgtg cgtaaagaca aatatctctg gggcgttatc acaggcctga cttattatgt
     8341 tttactgttg actgtctctg ttatggcaaa aggtggttgg gatatgagtg cagctcatgc
     8401 agttacaaca ttttttatgt gcacaggcgg cggaacactg ggtggaatgc tgtcataaaa
     8461 aaaagctttc aaaatgaaaa gatatatgat atactatgcc aagaatataa ttacataagg
     8521 aggatagagt tatggaacat atcaaaaccc tgaatacaaa gaatttacag aacactgtaa
     8581 aaaaaggtgg atgtggcgag tgccagactt cctgccagtc cgcatgtaaa acttcctgta
     8641 cagtaggaaa ccagagctgc gagcagaaat aagatcagct atggagaaat gagataagca
     8701 gcggaacttt tattccgctg cttatcttac gcttagaaag gattttagta aaatgagtct
     8761 gattcaccgt tataaaagca atggctttaa tattgtactg gatatcaaca gtggatgcat
     8821 ccatctggta gatgaggtta catatgaggt tcttccatat ctggaaaagg gccttgacac
     8881 agaagctatt gcagagaaac tggaaaacaa atataacaga gaagatattg agacatctgt
     8941 aaaagaatgt aataagctga aagaagatgg aatgcttttt acaaaagatg tttacgagaa
     9001 tgcaattgaa gaattttcaa ataaccggca gaccgttgta aaagcattgt gcctgcacat
     9061 tgctcatgac tgcaatctgg cctgccgtta ttgttttgcc gaagaaggcg aatatcatgg
     9121 cagaagagct cttatgtcct atgaagtcgg caagaaagct cttgatttcc tgatcgcgaa
     9181 ctccggttcc agaaaaaatc tggaagtaga tttctttggc ggcgagccgc tgatgaactg
     9241 gcaggttgta aaagatctgg taaaatatgg cagagagcag gaaaagcttc acaataagaa
     9301 attccgtttc actttaacaa caaacggagt tcttctgaac gatgaagtaa tggaattctg
     9361 caataaagag atgggcaacg ttgtactcag tgtggacgga cgtaaggaag tacatgacta
     9421 catgcgccca ttcagaaaag gtgcagggag ctatgatctg atcatgccga aattccagaa
     9481 gtttgcagaa tccagaaatc aggataaata ttatgtaaga ggtactttta cccaccataa
     9541 tcttgatttc tccaaggatg tgcttcatct ggcagacctt ggattcaaac agatttccgt
     9601 agagcctgta gttgcggctg atacagagga atatgcgatc cgcgaggagg atatcccgca
     9661 gatcatggaa gagtatgata ctcttgcaaa agaaatgatc aaaagagaga aagagggaaa
     9721 aggatttaac ttcttccatt ttatgatcga ccttacaggt ggtccttgtg tatacaagag
     9781 actgtcaggc tgtggttcag gaacagagta cctggctgta accccctggg gtgattttta
     9841 cccatgtcac cagtttgttg gtgaagaaca gtatctcatg ggaaatgtaa acgaaggtat
     9901 cacaaagccg gaaatccaga aagaattcgg cggatgcaac gtttacacaa agaaagactg
     9961 caaagactgc ttcgcacgtt tctactgtag tggcggatgt gcggcaaatg cattccattt
    10021 ccagggagat atcaaaggca attatgaaat cggatgcgaa ctccagagaa aacgtgtgga
    10081 gtgcgccatc atgataaaag ccgcactggc atgtgattag tggacaggaa tctgtctgac
    10141 tgataccgct gtcggctgtt atcataacag aaaatggctg gcaggcggat gaacatgacc
    10201 gcggacaaaa aatcaagaag ggaaaagaac tatgaagaaa agtaaaggaa tcgtagtgct
    10261 gcttctgaca ctgatcctga ctgtgttctt ttgctttact gcagccgtag gtatcggtcc
    10321 taccggaacc ggtgcagcaa aacacatcaa cacaggtctt gatcttgccg gtggtgtcag
    10381 cattacctat caggctaagg agagcaatcc gacaagcgaa gagatgtcag atacgatcta
    10441 caagcttcag aagcgtgtag agcagtacag tactgaggct caggtatacc aggaaggatc
    10501 agaccgtatt acagttgaaa ttcctggtgt tacagatgca gatactattc tgaatgatct
    10561 gggtaaacca ggttctctgt atttcatcac aaaagaagat gctgacggaa accagaactt
    10621 tactaccggc caggatggat atgttctctc caggactatg gatgagatta aggaatccgg
    10681 aagtgttgtt ctggaaggtt ctgatgtagc agatgcccag ggtggtgcaa tccagaatca
    10741 gggcacaagt ggaaaggaat atgtggtaag tcttactctt acttctgatg gagaaaacag
    10801 tggtaaaaca aaattcgcag aagctacaaa gaataatgta ggcaagcaga tcgctatcgt
    10861 ctatgataat aacattatca gtgctccgaa tgtaaatgaa gagatttccg gcggaaaagc
    10921 acagatcagc ggaatgtctg acctggaaga agcacagaac cttgcttctt atatccgtat
    10981 cggttctctg ggactggaac tggaagaact tcgttccagt gttgtagctg cacagcttgg
    11041 tgaagaagca atctctacaa gtgttcttgc aggtgcaatc ggtctgatca tagttatcat
    11101 ttttatgatc attgtatacc gtgtacctgg tgtagttgca ggcatcgcac tgattcttta
    11161 tacatcatta atgctgatca cgctgaatgc ctttgatatt actcttactc ttccgggtat
    11221 tgcgggtatt atccttggta tcggtatggc ggtggatgcc aatgttatta tttatgcccg
    11281 aatcagagag gaaatcggcg caggagtttc agtaaggaat tctattaagt ccggtttcag
    11341 caaagctttc tctgcaatct tcgatggaaa tatcacaacg ctgatcgcag cctttgtgct
    11401 aatgtggctt ggttcaggta ctgttaaggg atttgcttat acacttgccc ttggtattgt
    11461 aatctccatg tttacagcac tggttgtatc cagattggtt gtaaatgcac tttatgcagt
    11521 tggtgtgcgt gatccaaagt tctacggatc tgcaaaagaa cgtaaggcag ttgattttat
    11581 tggaaagaag aaagtatttt ttattatttc cattatcctg atcctctgtg gcccggcagc
    11641 gatgtttgct aattcacatg caggaaacaa agcattaaat tacagtcttg agttctcggg
    11701 cggtacttct acaactgtta catttaatga agatatggat atcaagacca ttgattctga
    11761 agtaactcct gttgtagaaa aggtgacggg agataaaaat gttcagccta caaaggtagt
    11821 cggaacaaat caggttgtta tcaagacacg ttctctgaat cagagcgagc gtgaagctct
    11881 gcagagtgca ctggttgaga aatttggtgt agatgacagc acaatttcca cagaaagcat
    11941 ttcttctaca gtaagtagtg aaatgcgtcg tgatgcaatc gtagccgtta tagtagctac
    12001 aatctgtatg cttctttata tatggttcag atttaaagac atccgttttg caagcagtgc
    12061 tgtattagcg cttctgcatg atgttctggt tgtacttgca ttctatgccc ttgccagagt
    12121 atctgtcggt aatacattta ttgcctgcat gcttacaatc gtaggttatt ctatcaatgc
    12181 tacaatcgtt atctttgacc gtatacgtga gaaccttcac agtagttcca gagagaaact
    12241 ggcagaagtc gtaaatacaa gtatcactca gactcttaca agaagtattt atacttcttt
    12301 tacaactttt gttatggtag ctgttcttta tatcatgggt gtttcttcta tccgtgaatt
    12361 tgcagcacct ctgatggttg gtgttcttat cggtgcatat tcttctgtat gtattacagg
    12421 tgcattgtgg tatgtaatga aaaagaaatt tacaggaaaa ggacagccgg caattgctgc
    12481 agcttccaca tccacaaagt cctcttcaaa accgaagaaa acacgtgatg tatcacagaa
    12541 agatccgact cagccaaaga agaaaaacag aaaaagagta gctgaacgtc tggctgccga
    12601 agaatcagct aagaaacagc agaatgatga tgctgaataa aagttactgt tcactccgtt
    12661 cacagtaaca aataaaacaa taattgtctg gaaaacaggc agacataaat atcccggggt
    12721 aaaactctgg gatattttta tgaggagaga aaatatatgg aaaaatgggt aatagctgca
    12781 aaaagagcag attttaacca gatcggtcaa cagtttcata ttgatccggt gattgcgaga
    12841 gtaatcagga acagagatgt gatcggagaa gataagataa gagagtatct gtcaggaaca
    12901 gtacaagagc ttccttctcc ctggctgatg aaagatatgg aaaaagctgt agatatcctg
    12961 gagagaaaaa tatcgcagaa agcaaaaatc cgtattattg gtgattatga tattgatggt
    13021 gtgacctcta catacatttt aatgaaaggt ctcgcaagga ttggagcaga tgtggatact
    13081 tacattccgg acagagtttc agacggatat gggattcatg cacatcttat agaaagagca
    13141 gaaacggatc gaatcgatac aatcgtgacc tgtgataatg gaattgctgc ggctgccgaa
    13201 atccagatgg caaaggataa gaaaatgaca gtgattgtta cagatcatca tgagattcct
    13261 tacagggagg aaaaggggga acgccggatg gtgcttccgc cggcagatgc gattttgaat
    13321 ccaaaacaat atgattgtcc atacccgaat aaaaacctgt gtggggcagt ggtggcattt
    13381 aaatatatta cagtactcta cgagagattt ggtgttccgg cagaggagct ggaagattat
    13441 tatgaactgg cggctattgc aacagtagga gatgttatgg atcttcaggg agagaacagg
    13501 attctggtaa aagaagggct gtgccgtctg aaaaatacca aaaataaagg attgcaggaa
    13561 ctgatccgcg caaattctct ggaagatgct aaaattacag cttatcatat cggatttgtg
    13621 ctgggaccat gtatcaatgc cagtggcaga ctggatacag ctgcccgttc tcttgcgctt
    13681 cttaatgcaa aaacaaagga agaagcagca aggcttgccg gagatcttac agctcttaat
    13741 cagagccgaa aagctctcac tgagaaagga aaagaagagg caatccggat catagagact
    13801 acagagctga aaaacgacag agtactggta gtctatcttc cggattgtca tgaaagtctt
    13861 gccggtatta tagcaggcag gatcagggaa aaatatcaca agcctgcctt tgtgctgacg
    13921 ggcggtgaga caagcgcaaa aggaagcgga agatcaatag aaagttactc catgtatgaa
    13981 gaactgataa agtgtgcaga cctgatgata cagtttgggg gccatcctat ggcagcaggc
    14041 ctttctatag aagaaaaaaa tatagaggaa ttccggagac gtctcaacgt aaactgtaca
    14101 ttgacggacg aagaactgcg tcctaaggtc gtgattgacg taccgatgcc tgtgtcttat
    14161 gtcacaaaag aactggtaga acagatttca cttctggaac cttttggaaa aggaaataca
    14221 aaaccggtct ttgcacagaa aaatctcaga gtgcttgatc acagtattat cgggaaaaat
    14281 aaaaatgcag taaaactaaa actccttgat ccgcagggaa tctcagtgga aggcatttat
    14341 ttcggagaag cggaggaatt tgtgaacttt atcagggaaa aagacagtgt ttctgttact
    14401 tattatccgg agatcaacag attcagggga cgagagagtc ttcagatcat tattcagaat
    14461 tactgttaac attaccgcct gttttgtatc tgccggtaag cctggaaata caaatgtcag
    14521 ggtttaacag taacttgatt ctgaaataaa aaggtgatat actatagaat atttatgagt
    14581 gaacagaaat ataacacaca ctggaggaga aataaaatga agaaaattga agattatgta
    14641 ttaagtatac cggattttcc tgaaccgggg attattttca gagatattac aagtgttctg
    14701 caggatgcag atggcctgca gcttgcaatc gactccatgc aggactgcct taaggatgta
    14761 gatgtggacg tgattgcagg aacagagtcc agaggtttta tctttggtgt accgatcgca
    14821 tataatcttc ataaaccatt tgtaccgatt cgtaaaaaag gcaaacttcc ccgcgaaaca
    14881 gtatctgtaa gctatgatct ggaatatggc agtgcagaga ttgaaatgca taaagattcc
    14941 ataaaaccag gtcagaaagt agttatcgtt gatgatctga tcgcaacagg cggtacgatc
    15001 gaagcagcga tcaagctggt ggaacagctt ggcggtgagg ttgtcaaggt tgtatttctc
    15061 atggaacttg caggtttaaa aggacgcgaa agactgaacg ggtatgacgt agcgtccgta
    15121 atttgttatg atggtaaata agcacagctg attgtgcagg acaggcaggt gggagcatat
    15181 gacagagata acaagaagta cagaagcaaa aaaagatgaa atgcagattg agaaagaaaa
    15241 actggaatct gtaaagagag cagatgcggc agtaaagacc atgcatgatt ttacaagtcc
    15301 ggaggtgctt tataaagaac tgataaacag tgttctgaag tatcatccat caacagatat
    15361 ttccatgata gagaaggcat ataaggttgc aagtgaagct catgaaggac agaaaagaaa
    15421 gtcaggagag ccatatatca ttcatccttt gtgtgttgcc atcattctgg cagatctgga
    15481 acttgacaaa gaaacgatag ttgcaggtct tcttcatgat gcagttgaag atacctggat
    15541 gacctatgag gaagtggaga aggaatttgg ttcagaggtc gcacttcttg tggatggtgt
    15601 taccaagctg ggacagttat cttattctgc agataaagta gaagttcagg cagagaacct
    15661 cagaaagatg tttcttgcca tggctaagga tatcagagtt attctgatca agcttgcaga
    15721 ccgtcttcat aatatgcgta ccttacagta tatgcgtcct gaaaagcagc aggaaaaagc
    15781 cagagagacc atggatattt atgctcctat tgccatgcgt ctgggtattt ccaagataaa
    15841 ggtagagctg gatgacctgt cgctgaaata tcttaagccg gatgtatatt atgacctggt
    15901 gcagaaggtt gccctgcgta aaagtgagag agaacagttt gtaggtgcga ttgtaaaaga
    15961 agttaagaaa catatggatg atgctaatat taaggcacag gtggacggac gtgtaaaaca
    16021 ttttttcagc atctacaaga agatggtaaa tcaggataag actattgatc agatttatga
    16081 tttatttgct gtccgtattc ttgtagatac agtgaaggat tgttatgctg cccttggtgt
    16141 gatccatgag atgtataagc cgattccggg acggtttaaa gattatattg ccatgccgaa
    16201 acccaatatg tatcagtcat tgcataccac attgatcgga cctaacggac agccctttga
    16261 aatccagatc cgtacttatg aaatgcacag aactgcagaa tatggtattg ctgcacactg
    16321 gaaatataag gagtcgtctg acggaaaggt tcctgtaggt aagagtgagg aagagaaact
    16381 gaactggctg cgtcagattc tggaatggca gagagacatg tctgataaca aagaattcat
    16441 gagtcttctg aagaatgacc tggatctttt tgcggacagt gtttactgtt tcactccaca
    16501 gggagatgtt aaaacacttc caagtggttc tacaccggtg gattttgcat acagtgttca
    16561 cagtgcagtc ggaaataaga tggtaggtgc cagagttaac ggtaagctgg ttccgattga
    16621 atatgagatc aaaaacggtg accgtattga gatcattact tcccagaact ctcagggacc
    16681 aagccgtgac tggctgaaac tggttaagag tacgcaggca aagaacaaga ttaaccagtg
    16741 gttcaagaag gaattaaaag aagataatat ccttaagggc aaggagatgc ttgcgcagta
    16801 tgcgcgtgca aaggggttta agatcacaaa ttatacaaaa acccagtatc tggaggccgt
    16861 tttgcgtaaa tatggtttca gggactggga ttcagtactt gcggcaattg gtcatggcgg
    16921 attgaaagaa ggtcaggttt tcaataagct ggtagaggca tatgataagg aaaataagaa
    16981 gaatctgaca gatgagcagg ttcttgaagc tgcttctgag acacaggaga agcttcacat
    17041 tgccaagagt aagagtggta ttgtggtaaa aggaatccat gatgtggcag tccgtttttc
    17101 caagtgttgt aatccgatcc cgggtgatga gattgtaggc tttgttacaa gaggacgtgg
    17161 aatcacgatc catcgtacag attgcgtcaa tgtgctgaat atgtctgaga cagacaggac
    17221 acgactgatc gaggcggaat ggcagcagcc tgataccaag gaaaaagaaa agtatatggc
    17281 tgagattcag gtttatgcaa ataaccgtac agggcttctt gtggatcttt ccaaaatatt
    17341 tacagaacgt aagattgacc tgcgaagtat caacagccgt acaagcaagc aggagaaggc
    17401 aactatttcc atgagctttg agattggaag caaagaggaa ctgcgttccc tgatcgagaa
    17461 gatccgtcag gtagaaagtg tcattgacgt agagagaact acaggctgat catggtaaaa
    17521 tctgttggaa cattatttta tggaactgct gcagattgac agaaaggaat aacatgaaga
    17581 atttagaatt acagaaatgt atattaggac ctgtatatac aaattgctat ctcctcaaga
    17641 ataaagaaac cggagaactg attattgttg atcccgcaga ttgtccggag aagattgaac
    17701 tgaagatttc ccggatgagt ggaaaaccgg tggcgattct tcttacccat ggacatttcg
    17761 accacattct ggctgcacag gcagtaaagg agaaatataa tattccgatt tatgcctgtc
    17821 gtcaggaaga ggagatgctg cgcgaaccct cgattaatat gactgtacat tatggacggg
    17881 gatgttctat tgtgccggat gtatttctgg aggatctgga tgttatcaga atggcgggat
    17941 tttctgttca gatgatccat acaccgggac ataccaaagg aagctgctgt tattatctga
    18001 aagatgaagg cgtattgttc agcggtgata cagtattcta tggttctgtt ggaagaacgg
    18061 attttccggg tggaagtaca gcagaaatcg tgaaaagtct ccataaactg gtagattcgc
    18121 ttcctgaaga gaccgaggtt ttccccggac atgatgcatc taccactatt ggttatgaaa
    18181 agaggtataa tccatttgtg taaaataggc attctgtttg agaacagaga ttttgaacat
    18241 gatgtttatg aactgatcaa agcgttttat cccgaagcgg agatacatac tctttatgaa
    18301 aatgctgaag cagagtatga cctccgcttc agtgtggaac gggataatga cagttatatc
    18361 ataaaatacg aaagggcaga gaatctgtcg aaacaggaga cagagcaaaa aggggtaatt
    18421 tccgcagaca tacttgctaa agagaatgca ggctgtggaa tacaggatgc tcatgctctg
    18481 agaaaagaga ataaagatac tatcaaatat gctctgtatc agttgttggt aaaactgacg
    18541 ggcagaactc ttccatgggg aaatctgaca ggaatacgtc ctgccaaact ggcaatggga
    18601 atgatcgaat ccggaatgaa aaatacggaa gcagcccggg agatgcgtga gagatatctg
    18661 gtaagtccgc agaaaacagc gcttgccatc actattgcaa acagggaaag agagattctg
    18721 aaggatattg actatgaaaa tggatacagc ctttatattg gaatcccgtt ttgcccaagt
    18781 atctgtctgt attgttcctt cagctcctat ccgctgaaag tgtgggagaa gagaacagat
    18841 gaatatgtgg aagctctctg ccgggaggta agagagactg ctcttatgat gaagggaaga
    18901 aaactggaca ccatctatat tggcggcggt acccctacta cactgcttcc acatcagatc
    18961 cgtaagctcc tggatacagt gggagaagct tttggctatg aaggactggc agagttcact
    19021 gtggaagccg gcagaccgga cagtatcaca cgcgaaaagc tgatgacgat cagggagtat
    19081 ccggtaacaa gaatttccgt aaatccacag accatgaatc aggaaaccct ggatattatc
    19141 ggccgcagac atactgtgga gcagacaaaa gaagcgtttc gtctggcaag agagctggga
    19201 tacgataaca ttaacatgga tctgatcgta ggtcttccgg gtgaggatat tcatatggta
    19261 gaacgtactc ttgaacagat tcgtgaactg gcaccggaca gtattaccgt acattcactg
    19321 gcagtgaaac gtgcagcaag gctgaatatt tttaaagaga aatatcagga aatgtctttt
    19381 gagaataatc aggagattat ggatctgacc atgaaaacag catatgaaat gggaatgggc
    19441 ccttattatc tgtacagaca gaagaatatg aagggaaatt ttgaaaatgt tggctatgca
    19501 aaggttgaca aagcgggaat ttacaatata ctgattatgg aggaaaaaca gcctatcatc
    19561 gcactggggg caggcggttc ttccaagctg gtctttgacc acggacagag aattgagcgt
    19621 gtggagaatg taaaagacgt ttccaattat atttcccgca ttgatgagat gatcgagaga
    19681 aaacggacag caatagctac ctggctgtag gatgtggagg taacattttg gacacagtac
    19741 aaaagacagc ggcaggttca cagcagagga tcctggaatt tgaccttgct tctgaactgc
    19801 atcatggaat gctggtaagt aatctggctt atgcggttgc ggaggagatg ggactgacgc
    19861 atgaacagtg ctatgagctt gcaatggcgg gaatgctcca tgatatagga aagctgaagc
    19921 tgacaagtta tatcaacgga caggagcagg atcctctggt gatcgaggaa ctgaagtatg
    19981 tccggatgca ttctgcattg ggatatgagg aacttaaagg gcagggatat tcggattttg
    20041 tattggagag tatcctgtac catcatgaga attatgatgg cagtggatat ccgtccaata
    20101 aagcaggtga tgacataccc
//
