LOCUS       c00016_gnlPro..        23249 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KOPMNMJB_16.
ACCESSION   c00016_gnlPro..
VERSION     c00016_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 17:18:06
            Original ID  :: gnl|Prokka|KOPMNMJB_16
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 12658
            Orig. end    :: 35907
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23249
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[22658:25907]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13249
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
     cand_cluster    1..23249
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /kind="single"
                     /product="Putrescine2spermidine"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..23249
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Putrescine2spermidine"
                     /region_number="1"
                     /rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /tool="gutsmash"
     CDS             complement(109..1200)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1043:Periplasmic binding protein-like domain (Score:
                     107.3; E-value: 3.4e-33)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_13"
                     /sec_met_domain="Peripla_BP_3 (E-value: 3e-33, bitscore:
                     107.3, seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDNGKPKYFSLMEQLRSGIVSGAIRPGEKLPSENELSQKYSLSR
                     HTVRKALGILEQDGYVEAFHGRGTYCSENVRHIKNSKNIAVVTTYISDYIFPRLIQGMD
                     NVLSVSGYSIILKNTANSRQKEARCLEELLKKDIDGLIIEPSKSEMICKHRNLYQNLDK
                     FEIPYVFIQGIYSEMRDKPHILMDDAQGGYLVTKYLLELGHKKIKGFFKADDMQGLERH
                     KGYVKALQESGIVYDPDDVVWFHTEDRKVKPALMAKEMVQSGQLPDGIVCYNDQIAVQV
                     MEELEKMGVRIPDDISITGYDNSLYAQRGSGITTIAHPQEKLGEMAAELILEKINGVPE
                     TESRVERLIHPELIIRGSCRKAE"
     CDS             complement(1392..2279)
                     /locus_tag="ctg16_14"
                     /transl_table=11
                     /translation="MKKLRTFAVSMIIAAIGLLIYCAGFYIKSYEQNLAAKQEYAELSR
                     MAGMKNREDAGLLADGKKTDEDSSTENSEKKRRKKQRRFSKSKNKNHADEIRESFGISW
                     ENLRKINSQTVAWITVPGADISYPVVQAADDEYYLKHNFRGEEDLFGCIFLEHDIKKNF
                     TESHSILYGHNIEGNMMFANLNRYEQPEFLKKCPEIEITTPKRKFLYKIFSVEQASSQS
                     PAFEYGYKLSSPAYRRQLSILKNNSMYDTGVEPDETERMVTLITCNSRLDKEIRMAVHG
                     ICHECYDIEKAEPK"
     CDS             complement(2276..6973)
                     /locus_tag="ctg16_15"
                     /transl_table=11
                     /translation="MKHNFKLKERLGALLLAMLFILQAILGLVPVCVTQAAPLTVETWD
                     SDKVVDYGYRFNMKFQPGITTYESFGCDNLDREAFSDNGKSERDTECVRVGADYKAGSA
                     GMRYNNVGKDGNGNIVDVRLILVGVENAEPRYDLRTAESIVQNKGGATFAWKDNEAYPM
                     VGFSKNSIGVFIYSVGYAKVKFQFLKHGTEETLPISGHGTIRDIDAGQGVRIPSDSSLD
                     NAYVLKNNDYLTVDENSVSSPLGSVEPDDPRGWLNLFYNTDNFTVEFCHQFRLDKWDKS
                     REDAIAKAGSQERWAEITRNKYLDPSGNSYCPNFKGQKYCKAYAYFDFTSYCFGDVEMK
                     KAPEKRVGEANCTWEQAAAASKEKPFGIRQGQEFQYMIRAEVTPNRLKSFVVQDILEDC
                     LVIEDASKVSIVNDAGQTVTDWFDVAVEGQKVTCSAKAESIQDEAFTDNQTYTFTLKVR
                     QRPESEINISKYLAEDGYSILVPNHASMSYERTNGSGDTMDTETVWVKGVIPPELEVKK
                     NTSQYEWKTGDIIDYEVLVSQTKQDVKAVNVVITDEIPSCLQLLEGQYTVETSQGGENC
                     TLTGQGENGWKAECPSLKYGETITIRFKCQASADSNGQEWENIVTATADNLINPETGEQ
                     ESRKDMAEVWPNSPQLEIDKTADKYEWQAGEQVAYRIVVNNVTAGTIAKDVTITDIGLP
                     QGLVLAGGAQSMEVLGVQQQVNYPVPDKKTGQAYEARPVDSQLNADENGFSFYCSYVPY
                     SQPVTIIFHCIAQEEANGHESVNAATVKAANTDEKSDDAEVYVNSGEFWIEKSADHYEW
                     QVGEQVQYNVVVENKKAGTVARNVTVWDTGMPAGLALSSAEDVSVSGIPQNITQLTAGT
                     EDVLNQLNPEFYNETSEKPVNYEFLQEGSGWRLNISDLPPNTPVMISFLCTVTEAANGM
                     ESINVANVQAQNAPVSQDDAEVYVNTAVLSIEKSFQNPYLAAGDGRAENEFRVGEQVNY
                     QVTVNNLQKGSIARNLVISDLSLPEGLVLDGAEDAVTVSGVPAVIQNPVAGTDDAGNQL
                     NPENYKETVEKPVSCQVTRQGTGWIVTISDLPYQTPVTVNFRCTAQESVNGMEIVNTAQ
                     AYADNAQKVKDSSKIWVNSPVLKVEKTTDKPFYKYGDIITYRIVLTQEQTGCVARNVTL
                     QDVIDTQGVRLLKDSVILVDEKGNVADADVQINDDNTFLMSTGRTLVRDSRYSICDNDK
                     GGLFEQVMYNPLDCQEQKSMIVEYQAAVIDAALAGQKVHNTAVADSSEKIPATGEAETE
                     VHSPILEIVKESDKKEYASGEKGYYKLTVRQLREDVTDQNIVIEDKLETQGASIVKDSI
                     FVKKNGIELKDAKIEADDTGFVIQTGASLSDKDKIEVCYEVVFKTESTEPEKIVNTAKA
                     RGDISPETAAQQEVYVKIKAEPTATPTPSATPKPTETPKPTETPKPTEVPKPTEQPKAT
                     PKPSVPGTCPKMTPVPTKAPLASYNGGNNGGTTSGNGGSSYGNSGGYGSYQGGSMAGSS
                     KTGDVRPFKMMAVLGLLGVGLLTGGVVIYRRTVSGKRNIKGMPRK"
     CDS             complement(7072..7197)
                     /locus_tag="ctg16_16"
                     /transl_table=11
                     /translation="MKIYAGFQKRNPAQNLKNFKNLKNLKCKRSCFTILIPLEYL"
     CDS             complement(7194..7655)
                     /locus_tag="ctg16_17"
                     /transl_table=11
                     /translation="MNRKEFLEILRSQLAGQMQEGKAAAHIRYYEDYIQSQVRGGRSEQ
                     EVLQELGDPHLIAKTLIDTDDGSTQEDYGEYSSYGSSYGNETELPHQQEKRWKKVIDLS
                     TWHGRAVVIAAAAVIIILLILIIGVAIPFFIILAIILYFLSWLKKRNNQ"
     CDS             complement(7883..8761)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CN_hydrolase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_18"
                     /sec_met_domain="CN_hydrolase (E-value: 3.5e-55, bitscore:
                     178.9, seeds: 52, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRNVTVAAVQMRCSKSVEKNIAHAEELVRQAAAKGAEIVLLPELF
                     ERPYFCQERRYEYYEYAQTAEENLAVRHFSRVAAELGIVIPVSFYEKEVNNTYNSVAVL
                     DADGKNLGIYRKTHIPDDHYYQEKFYFTPGDTGFKVFDTRFGTIGVGICWDQWFPETAR
                     CMALQGAELLFYPTAIGSEPILECDSMEHWRRCMQGHAASNLIPVIAANRIGEETVEPC
                     PENGMQKSALNFYGSSFITDNTGALCAELPGGEEGVLVSTFDLDALKADRLNWGLFRDR
                     RPEMYAKIVGK"
     CDS             complement(8842..9966)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PAD_porph"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_19"
                     /sec_met_domain="PAD_porph (E-value: 3.3e-128, bitscore:
                     419.2, seeds: 436, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEVTEKNRTKYRMPGEFEPHEGCVMIWPERPGSWNYGAREAQKAF
                     VKVAEAIGESEKVYMLVSKAQMENAKNQLGNVSGVTLLECETDDAWARDVGATMVLDEK
                     GAVCGVDWQFNAWGGDFDGLYRNWEKDDRVAAFICRTLGCPCLDARPFVLEGGSIHSDG
                     EGTLIVTEACLLSQGRNPQMSREQIEEQLKYWLGVHKIIWLPCGIYQDETNEHVDNVCA
                     FVRPGEVVLAWTEDETDPQYAMSLADLKVLEQETDAKGRKFKIHKLPIPQKPVCLTRED
                     VDGFVFEEGEDEREAGERMAASYVNFYISNGGIILPQFGDENDKRAVEILQKCFPERRI
                     YPIDARAIIVGGGNIHCITQQIPGKISDLDAEKL"
     CDS             complement(10001..11089)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Orn_DAP_Arg_deC"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_20"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 1e-13, bitscore:
                     43.3, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VIDEKKMRENLEILKKVQEDTGCKILLAQKAFSGFALYPMIGKYL
                     AGTTASGLFEARLGHEEMGKENHVFSPAYRTEDMEELDRICDHIIFNSTAQLKKFKEVC
                     TRASLGLRINPECSTQGDHAIYDPCAPGSRLGVTRENFDVECLKWIDGLHFHTLCEQNA
                     DDLEKTLQVIEEKFGEFLSEVSWLNMGGGHHITREDYDVKRLEKCIQHMKETYDLDIYL
                     EPGEAVALNAGYLVTEVMDIVENGIRTLVLDASAACHMPDVLEMPYRPPLKDSGEAGEK
                     AYTYRLSSCTCLAGDVIGDYSFDREIRIGDKLYFMDMAIYSMVKNNTFNGMPLPDIAVM
                     HEDGECEVIRHFGYEDFKSRLS"
     CDS             complement(11112..12392)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Sacchrp_dh_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Sacchrp_dh_NADP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_21"
                     /sec_met_domain="Sacchrp_dh_C (E-value: 2.1e-43, bitscore:
                     141.1, seeds: 375, tool: rule-based-clusters)"
                     /sec_met_domain="Sacchrp_dh_NADP (E-value: 6.4e-36,
                     bitscore: 115.3, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRLLVIGCGGVASVAIRKCCQNSDVFTEIMIASRTKEKCDALKE
                     KIESTTKTKIETAKVDADNAEEVAELIRAYKPDAVLNVALPYQDLTIMDACLEAGADYI
                     DTANYEAEDTEDPTWRAIYEKRCKEKGFTAYFDYSWQWAYDEKFKKAGLTALLGTGFDP
                     GVTSVFSAYALKHYFDEIHTIDILDCNGGDHGYPFATNFNPEINLREVSANGSYWEDGH
                     WVETEPMEFKSVYDFPEVGKKDMYLLHHEEIESLAKNIPGVQRIRFFMTFGQSYLTHMK
                     CLENVGMLSTAPVEFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGVKDGKEK
                     SIYIYNVCDHQECYKEVESQAISYTTGVPAMIGSMMVVTGQWKKPGVFNVEEFDPDPYM
                     EALNKWGLPWKVCEDPELVKVWKANED"
     CDS             complement(12389..13249)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synth"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synt_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_22"
                     /sec_met_domain="Spermine_synth (E-value: 4.2e-53,
                     bitscore: 171.4, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Spermine_synt_N (E-value: 2.5e-15,
                     bitscore: 48.0, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELWYSEFHTGNVKLSVRINRQLFSGESEFQRIDVFESEEFGRFV
                     ALDGEIVFSDKDEFIYDEMVTHVPMTVHPNVKNVLIIGGGDGGVARELIHYPQIESIDV
                     VESDKMFVDVCAEMFPDIAQGLKDERVNIYYEDGLRFLRNKKAGYDLIINDSTDPLGHT
                     EGLFTKEFYGSCYKALRDDGIMVYQHGSPFYDEDEVECRKMHRKVFRSFPVSRVYQAHI
                     PTCPSGYWLFGFASKKYHPLEDFRPERFDDLNIETWYYTTNLHRGAFMLPKYVEDLLEE
                     EENSL"
     CDS             complement(13252..14709)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_7_arginine"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_23"
                     /sec_met_domain="OKR_DC_1_C (E-value: 1.4e-13, bitscore:
                     43.2, seeds: 113, tool: rule-based-clusters)"
                     /sec_met_domain="OKR_DC_1_7_arginine (E-value: 3e-126,
                     bitscore: 413.0, seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDYERQQHAPIYEALERFRKKRVVPFDVPGHKRGRGNPELAQLLG
                     EKCVGLDVNSMKPLDNLCHPVSVIREAEELAADAFGAAHAFLMVGGTTSAVQSMILSVC
                     KAGDKIILPRNVHKSAINALVLCGAIPVYVNPEVNAQLGISLGMEVSQVEKAMDENPDA
                     VAVLVNNPTYYGICSDLRTIVKKAHARGMKVLADEAHGTHLYFGRNLPVSGMAAGADMA
                     AVSMHKSGGSLTQSSLLLLNKSMNAEKVRQIINLTQTTSASYLLLSSLDISRRNLALRG
                     EESFEKVAGMAQYAREEINEIGGYYAYGMDLINGTSVFDFDVTKLSIYTLGNGLAGIEV
                     YDLLRDEYDIQIEFGDICNILAYISIGDRLQDIERLVGALADIERLYKKDSTGMLSGEY
                     IAPAVVASPQQAFYAEKESLPMEQAAGRISGEFVMCYPPGIPILAPGEMVTQEIVEYIL
                     YARDKGCSMQGMEDPKVEHLQVLKGGI"
     CDS             15771..17456
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FTHFS"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_24"
                     /sec_met_domain="FTHFS (E-value: 2.3e-275, bitscore: 905.8,
                     seeds: 408, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGFKSDIEIAQECKMLPITQIAEKAGIDDKYLEQYGKYKAKIDYN
                     LLKESDKKDGKLILVTAINPTPAGEGKTTTTVGLADGMQRLGKSVMVALREPSLGPVFG
                     VKGGAAGGGYAQVVPMEDINLHFTGDFHAIGAANNLLAAMIDNHIFQGNALNIDPRKIT
                     WRRCVDMNDRQLRNVVDGLGGKTNGMPREDGYDITVASEIMAVLCLASDIKDLKERLSK
                     IIIGYTYGKVSEQKPVTAGDLHAEGAMTALLKDALKPNLVQTLEHVPAIVHGGPFANIA
                     HGCNSVTATKMAMKLADYAITEAGFGADLGAEKFLDIKCRMAGLKPSAVVIVATVRALK
                     YNGGVAKADLNNENLEALEKGIPNLLKHVSNIKNVYKLPCVVAINAFPTDTKAELDFVE
                     AKCKELGVNVALSEVWAKGGEGGIKLAEEVIRLVEEPNDFSYAYELEGSIEDKLNQIVQ
                     KVYGGKKVVLTANAQKQAKQLEALGFGNCPICVAKTQYSLTDDQTKLGAPTDFEVTVRN
                     LKISAGAGFIVALTGEIMTMPGLPKVPAAERIDVDETGKITGLF"
     CDS             complement(17564..19006)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lyase_1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FumaraseC_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_25"
                     /sec_met_domain="Lyase_1 (E-value: 1.1e-94, bitscore:
                     309.1, seeds: 17, tool: rule-based-clusters)"
                     /sec_met_domain="FumaraseC_C (E-value: 4.9e-22, bitscore:
                     70.0, seeds: 737, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGGRITMKKTDYRVERDSIGVKDIPEDVYYGVQSLRAAENFHITG
                     LNMHPEIINSLAYIKKAAAITNCEVGLLEKKKAQAIVQACDEIVSGKFHNEFIVDPVQG
                     GAGTSLNMNANEVIANRAIEILGGKKGDYTIINPNDDVNCGQSTNDVIPTAGKMTSLRL
                     LQNLKKQLLRLYDALNEKAVEFDHVIKMGRTQMQDAVPIRLGQEFKAYSVAIMRDIHRM
                     DKAMDEMRTLNMGGTAIGTGINADEGYLRRIVPNLTEISGMDFIQAFDLIDSTQNLDPF
                     VAVSGAVKACAVTLSKMSNDLRLMSSGPRTGFGEINLPAKQNGSSIMPGKVNPVIPEVV
                     NQVAFNIIGNDVTITMAAEAGQLELNAFEPIIFYCMFQSIDTLGYAVQTLVDNCIVGIT
                     ANEERCRYLVENSVGIITAISPHLGYQKAADIAKKAIKTGESVRSLILKEKLMDEDELN
                     RILDPIHMTEPGISGKDYLIKK"
     CDS             19104..20039
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     57.3; E-value: 3.7e-18)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg16_26"
                     /sec_met_domain="LysR_substrate (E-value: 1.9e-33,
                     bitscore: 107.4, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 3.3e-18, bitscore: 57.3,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFQGMEYIYEVYKEKSFSKAATALFISQPSLSANVKRVENRIGYP
                     IFDRSTKPLQLTEVGKHYIQAVEKVMDIENNLENYLLDLGNLKTGTLNVGGSNFFSSWI
                     LPPLIADFSQKFPHVQISLVEESTAKLSQFLQAGKLDLVIDNCILDNQIFEHYTYQKEQ
                     LLLAVPKNYSVNNRLQKYQIPIEEIRNGQFRSSHIPSVPLNKFENEPFIILRSDNDTGK
                     RALTICQENHFSPSVVFRLDQQMTAYNIACLGMGITFIGDLLLSRVPTNSELVFYKLPG
                     QSSKRTVFFYWKKGRYISRAMEEFLKLPFS"
     CDS             complement(20118..21119)
                     /locus_tag="ctg16_27"
                     /transl_table=11
                     /translation="MKRILLILTGGTIASVETDQGLRPGISEEELRESLSGITDFCQVE
                     ILSLLNVDSTNIQPEHWQMIVQAIEERFDCYDGFVITHGTDTMAYTAAALSYMIQNPHK
                     PVVITGAQKPLVKTVTDARKNLRDSFRFACEENVNGVFLIFNGEVILGTRARKVRSKSF
                     NAFDSINYPIVAFIDNDRVIRYVDISGDSGPTSFYSRLVPKVFLLKLVPGITPDILDYI
                     SDHYEAVVIESYGVGGIPFADERNFLEKLECLNRKKCIVVIATQVMLEGSDVELYEVGF
                     RAMSRYHLLQAYDMTTEAIVAKLMWLLGKCNDFESFQREFYTPVSCDLLRCE"
     CDS             complement(21116..22549)
                     /locus_tag="ctg16_28"
                     /transl_table=11
                     /translation="MEEKNNTTVDIPENDGEFMLEPVPMSARRSTRSQFMVWIGFGYAV
                     TGLIIGGTLGGYGGTGGMPPSQAMMAIILGMGALYLVTCFLGIVAQKTGLNLSLLARFS
                     YGYKGSAIPMAVMALLTLGWFSSILGMIGDIWGAFIGNPTGVIVFDPSKYGFSGVAPIT
                     LEVVIACVFWGLVFTFTAVKGMGAIEKVSDVFAPLILIVAVVVGIIYVVQCGGVGGFLD
                     KANKLHGLGMGEAITAVVGSWIAGAVMGVDMFRFNKSTKAVWGCAAACFILTNPILNIV
                     GYIGTVYIGNFNYVLWMLGVNFIVAILGVVVWTTALWTTDNSELYCNALYTGPSLNAFG
                     INVSRKKLVIIAGVTGTVLGSFAFYQLFFANFINILGSMAPPLCAPILADYFVVGRKNK
                     DKYNMELLNKHPNFRWAGVISFAVGAILGFVFQYKITLPLDLPSGLVAMVISFIVYIAI
                     YKMTPDAAVDEKLVSGLKK"
ORIGIN
        1 cctgttttca tgataaaatt cctcctggat ttttttatta ttttcagatc ttctgctgct
       61 ttccactgca tcttcaatct gtgtgtttac tgttaatatc tgatgttttt attctgcttt
      121 tctgcatgat ccccgtatga tcagttccgg atggatcagt ctttcaaccc tgctctccgt
      181 ttcaggaact ccgttgatct tctcaagtat aagctccgct gccatttctc ccagcttttc
      241 ctgcggatga gctatcgttg tgattccgct tccccgctga gcatacagtg aattgtcata
      301 accggtaatg gaaatatcat ccggtatcct gactcccatt ttctccagtt cttccataac
      361 ctgaacagca atctgatcat tgtaacagac gattccatcc ggaagctgtc cgctctgtac
      421 catttctttt gccatcagtg caggttttac tttcctgtcc tctgtatgaa accagacaac
      481 atcatcagga tcatagacaa tccctgactc ctgtaaggcc ttcacatatc ccttgtggcg
      541 ctccagtccc tgcatatcgt ctgccttaaa gaaacccttg atctttttat gtcccagttc
      601 cagcagatat tttgttacaa gatagcctcc ctgtgcatca tccataagaa tatgaggttt
      661 atccctcatt tctgaatata ttccctgaat aaacacatac ggaatttcaa atttatccag
      721 attctgataa agatttctgt gtttacagat catctcactt ttgcttggtt caatgatcag
      781 tccatcaata tctttcttca gaagttcctc cagacatctg gcctctttct gtctgctgtt
      841 tgctgtgttt ttcaggataa tactgtaacc gcttactgaa aggacattat ccattccctg
      901 tatcagtctc ggaaaaatat aatcagaaat atatgtggtc actaccgcaa tattctttga
      961 attctttata tggcgcacat tctcagagca ataagtacct ctcccgtgaa atgcctccac
     1021 atatccgtcc tgctccagga ttcccagtgc cttacgaacc gtatgtctgc tcagggaata
     1081 tttctgtgaa agctcatttt ctgaaggaag cttctctccc ggccggatag ctcctgacac
     1141 aataccactt ctaagctgtt ccatcagtga gaaatatttc ggctttccat tatctgtcat
     1201 gttttcttcc ctcctgtatt taggatacaa cttgtacgca cgtacgaaca agttgttttt
     1261 tatgcataaa ttatacaaaa tatcgaggga tttttcatta gttttttcca aaacgcctcg
     1321 agggatagtg atgtgtgaac agtaacagtt catcctttac gaaagttacc aatatccgat
     1381 tgatttcaac attacttcgg ctcagctttt tctatatcat aacattcatg gcaaatccca
     1441 tgtaccgcca tacgtatttc tttatccaga cgtgaattac aggtgatcag agtcaccatt
     1501 ctctctgttt catcaggctc tactcctgtg tcatacatgg aattattttt caatatagat
     1561 aactgtctcc tgtatgcagg actggataac ttgtatccat attcaaatgc cgggctttgg
     1621 gaagatgcct gttccacaga aaaaattttg tacagaaact ttctttttgg tgttgtgatc
     1681 tcaatttcag gacatttttt cagaaattca ggctgttcat aacggttcag atttgcaaac
     1741 atcatattac cttctatgtt atgcccgtaa agaatactgt gggattctgt aaagttcttt
     1801 tttatgtcat gttccagaaa aatacagcca aacagatctt cctctcctct gaaattatgt
     1861 ttcagataat attcatcgtc tgccgcctga actacaggat aagaaatatc ggctcccgga
     1921 acagtaatcc aggcaactgt ctgagagttg atctttctta aattttccca ggaaatccca
     1981 aaggattccc tgatttcatc tgcgtggttt ttgttttttg atttagaaaa tcttctctgt
     2041 ttttttctgc gttttttttc actgttttct gtactgctgt cttcatcagt ttttttgcca
     2101 tctgccaata atccggcatc ttctctgttc ttcatccctg ccatccggga aagctctgca
     2161 tattcctgct ttgctgcaag attctgttca taacttttta tatagaaacc ggcacaatat
     2221 ataagaagcc caattgctgc tatgatcata cttactgcaa atgtcctgag ttttttcatt
     2281 tccgcggcat accctttata tttcttttcc cggaaacagt tcttctgtag atcaccacac
     2341 ctcctgtcag cagtcccact ccgaggagtc caagaacagc catcatttta aacggtctga
     2401 catctcctgt tttagaactt cctgccatgg aaccaccctg atagcttccg tatccacccg
     2461 aatttccgta actgctgcct ccgtttccgg aagttgtgcc tccattattt ccaccattgt
     2521 aagatgccaa cggtgctttc gtcggtacag gagtcatttt cgggcaggtt cccggtacag
     2581 atggttttgg tgtggctttt ggctgctctg tcggtttcgg tacttctgta ggttttggtg
     2641 tctctgtcgg ctttggtgtt tctgttggtt tcggtgttgc agacggtgtt ggtgtggcag
     2701 tgggttctgc ttttattttc acatatacct cctgctgcgc cgcagtttcc ggtgaaatat
     2761 ctcctcttgc tttcgctgtg tttacaattt tttcaggctc tgtgctttct gttttaaata
     2821 ccacttcata gcagacttca attttatcct tatctgacaa cgatgctcct gtctgaatta
     2881 caaatcctgt atcatctgcc tctattttgg catctttcag ctctatgccg tttttcttca
     2941 caaaaatgct gtcttttaca atagaagccc cttgggtttc cagtttatct tcgataacaa
     3001 tattctgatc tgtgacatcc tcacgcagtt gtcttactgt cagcttatag tatcctttct
     3061 caccggacgc atactctttc ttatctgatt ccttcacaat ttccagaatc ggactgtgta
     3121 cctctgtctc tgcttccccg gttgcaggta tcttttcact gctgtctgca actgcagtat
     3181 tgtgcacttt ctgtcctgcc agggctgcat caatcactgc tgcctgatat tccacgatca
     3241 tacttttctg ttcctgacag tccagaggat tatacattac ctgctcaaaa agaccgcctt
     3301 tatcattatc gcagatacta tatctgctgt ccctgaccag tgtcctgcct gttgacatca
     3361 ggaaagtatt atcatcattg atctgtacat cagcatctgc cacatttcct ttctcatcca
     3421 ccagaatcac cgaatccttc agaagacgta ctccctgagt atcgatcaca tcctgcagag
     3481 taacattacg cgccacacat ccggtctgct cctgtgtcag gacaatgcgg tatgtaataa
     3541 tatcaccata tttgtaaaat ggtttgtccg tcgtcttctc tactttaaga acaggcgagt
     3601 tcacccagat ttttgaggag tcctttactt tctgtgcatt atctgcatat gcctgtgctg
     3661 tatttacaat ctccatccca tttacgcttt cctgcgcagt acagcggaaa ttaacagtca
     3721 caggtgtctg atacggaaga tctgaaatcg tcacgatcca tccggttccc tgacgtgtaa
     3781 cctgacagct gaccggtttt tccactgttt ctttataatt ttccggattc agctgatttc
     3841 ctgcatcatc agttcctgcc accggattct gaataacagc cggaacaccg cttacagtaa
     3901 cagcatcttc agctccgtcc agaaccagcc cttcaggaag ggaaagatca ctgatcacaa
     3961 gatttcttgc gatagatccc ttctgaagat tattaaccgt aacctgataa ttcacctgtt
     4021 ctcctacccg aaattcattt tccgcacgtc cgtccccggc tgccagatat ggattctgaa
     4081 aacttttctc aatagaaaga actgctgtat ttacatacac ttctgcgtca tcctgcgaaa
     4141 caggggcatt ctgcgcctgc acattggcaa cattaatgct ttccattcca tttgccgctt
     4201 ccgtaactgt gcaaaggaaa gaaatcataa ccggagtatt tggcggaaga tctgaaatat
     4261 tcagtctcca tccgcttccc tcctgaagaa attcataatt caccggtttc tctgatgtct
     4321 cattataaaa ttccggattg agctgattca aaacatcttc ggtccctgct gtcagctgcg
     4381 taatattctg tgggattccg cttaccgata catcctctgc cgatgaaagc gcaagtcctg
     4441 ccggcatacc ggtatcccag acagttacgt tccgggccac tgtacctgct tttttattct
     4501 ccaccaccac attgtactgt acctgttctc cgacctgcca ttcataatga tctgcagatt
     4561 tctcaatcca gaattctcct gaatttacat atacttctgc atcatcagat ttctcatctg
     4621 tattagcagc ttttacagtt gctgcattta cgctttcgtg tccatttgcc tcttcctgtg
     4681 cgatacaatg gaaaataatc gttacaggct gactgtatgg tacataagaa caataaaagg
     4741 aaaatccgtt ctcatctgca ttcaactgag aatccacagg tctcgcttca tatgcctgtc
     4801 ctgttttctt atccggtaca ggatagttta cctgctgctg aactcccagt acttccatgc
     4861 tctgtgcacc acctgccaga accagtccct gcggcagacc aatatcagta atagttacat
     4921 ctttcgcaat cgttcctgcc gttacattat tcaccacgat ccggtaagct acctgctctc
     4981 ctgcctgcca ctcatattta tctgctgttt tgtcaatttc aagctgtgga ctgttcggcc
     5041 atacttctgc catatccttt ctggattcct gttctcctgt ctcaggattg atcagattat
     5101 ccgctgttgc agtcacaata ttttcccatt cctgtccatt ggaatccgca gatgcctgac
     5161 atttaaaacg gattgtgatc gtctccccat acttcaggga cggacactct gctttccatc
     5221 cattttctcc ctgtccggta agcgtacagt tctcacctcc ctgactcgtc tctacagtat
     5281 actgcccttc cagaagctgc agacatgatg gaatctcatc tgtaataaca acatttactg
     5341 cttttacatc ctgttttgtc tgagaaacca gaacctcata atctatgata tctcccgttt
     5401 tccattcata ctgagaagta tttttcttta cttccagttc cggtggaatc acacccttta
     5461 cccacactgt ttccgtatcc attgtatcgc cgcttccgtt tgtacgttca taactcatgg
     5521 atgcgtgatt cggtacaaga atactgtatc catcctctgc aaggtatttt gaaatgttga
     5581 tttctgattc cggtctctgg cgtactttta aagtaaatgt gtaagtctga ttatctgtaa
     5641 atgcttcatc ctgaatactc tctgctttgg cgctacaggt cactttctgt ccttcaacag
     5701 caacatcaaa ccagtctgtc actgtctgcc ctgcatcatt cacaatactg accttagatg
     5761 catcctctat aacaagacaa tcctcaagta tatcctgtac cacaaaggat ttcagtctat
     5821 tgggtgtcac ctctgcccgg atcatatact gaaattcctg tccctgacga atgccaaaag
     5881 gtttttcttt tgatgcggca gctgcctgtt cccatgtaca gtttgcctct cccacacgtt
     5941 tctcgggcgc ttttttcatc tcaacatcac cgaaacaata ggatgtaaaa tcaaaatatg
     6001 catatgcttt gcagtatttc tgtcctttaa agttcggaca ataactgttg cctgatggat
     6061 ccagatattt atttcttgta atctctgccc atctttcctg agaaccggct tttgcaatag
     6121 catcttcacg acttttatcc catttatcca gcctgaactg atgacagaac tctaccgtaa
     6181 aattatctgt attataaaaa agattcagcc atcctctcgg atcatccggc tcaacagaac
     6241 caaggggtga gcttacagaa ttttcatcta ccgtcagata atcattgttt ttcagaacat
     6301 atgcattatc cagactgctg tctgacggaa tacggactcc ctgtcccgca tcaatatcac
     6361 gtatggttcc atgaccactg atcggcagtg tttcttctgt tccatgcttc agaaactgaa
     6421 acttaacctt tgcgtatcct acagaataaa taaatacacc gatactgttt ttggaaaaac
     6481 caaccatcgg ataagcttca ttatctttcc aggcaaacgt agctccgcct ttattctgaa
     6541 caattgattc tgcagtgcgc agatcatagc ggggttctgc attctctact cccacaagaa
     6601 tgagtctgac atcaacaata tttccatttc catcttttcc tacattgtta taacgcatcc
     6661 ctgcgcttcc ggctttatag tccgctccta cacgaacgca ctctgtgtca cgttcgcttt
     6721 ttccattgtc tgaaaaagct tccctgtcca gattatcaca cccaaaagat tcatatgtgg
     6781 taattccggg ctgaaacttc atgttaaagc gataaccata atctacaacc ttatcactgt
     6841 cccatgtttc tacagttaac ggtgccgcct gggttacgca gacaggcaca agccccagaa
     6901 ttgcctgcag aataaaaagc attgcaagca gcaaagctcc aaggcgttct ttcagtttga
     6961 aattgtgttt cattttccgt ctcctttccg aacaaaaata taaaaatgaa tgtgggattt
     7021 ttccctgcac aaggcaggat taaagaatag aaataagtgg aaattgtatg attataaata
     7081 ttcaagggga attaatatcg tgaaacaaga acgtttacac ttaagatttt ttagattttt
     7141 aaaattttta agattttgcg cagggtttct tttctgaaac cctgcataga ttttcattga
     7201 ttatttcttt tcttcagcca tgaaagaaag taaagaataa ttgcaagaat aataaaaaac
     7261 ggaatcgcaa ctccgattat cagtatcagt aaaataatta taacagccgc tgctgcaata
     7321 acaacagccc tgccatgcca ggtagaaaga tcaattactt ttttccatcg tttctcctgc
     7381 tgatgaggaa gctctgtctc attgccataa ctgcttccgt aagaagaata ctctccgtaa
     7441 tcttcctgtg tacttccatc atctgtatcg atcagagtct ttgctatcag atgtgggtct
     7501 cccagttcct gcagtacttc ctgctctgaa cgtccgccac gtacctgaga ctgtatataa
     7561 tcttcataat acctgatatg tgctgctgct ttgccctcct gcatctgacc ggcaagctgg
     7621 cttctcagga tttccaaaaa ttcttttctg ttcatctttt acactccatt ttgccagaaa
     7681 tacatgtcaa aactctactg ctcgctccgt tatcagtaac gtttgtactc ttattttacc
     7741 atatataccg caggtagcaa ctaatataat cataaacttt ttatgaaatt cttataaact
     7801 cagttactgt tcactccgtt ctcagtaact gagcaaaaat tcattccaga ttacctgcgg
     7861 caatggaagt ttggctcgta tgtcatttcc cgacaatttt tgcatacatc tccggtctgc
     7921 ggtctctgaa aagtccccag ttcagtctgt ctgcctttaa tgcatccaga tcaaaagtgc
     7981 ttacaagcac cccctcttcc cctccgggca gttctgcgca gagagcacct gtgttatctg
     8041 taataaaaga ggaaccgtaa aaattaagag cagatttctg cattccgttt tccggacatg
     8101 gctctactgt ttcctcaccg attctgttgg cagcgatcac agggatcaga ttggaggcgg
     8161 catgtccctg catacatctt ctccagtgtt ccatgctgtc acattccagg atgggctcac
     8221 ttcctatggc agtgggataa aagagaagct ctgctccctg caacgccata catcttgctg
     8281 tttccgggaa ccactgatcc cagcatattc caactccgat ggttccaaat ctggtatcaa
     8341 aaaccttaaa accggtatct cccggtgtga aatagaattt ttcctgataa taatggtcat
     8401 ccggaatatg tgttttccga taaatgccga gattcttccc atctgcatcc agaaccgcaa
     8461 cgctgttata agtattattg acctcttttt cataaaagct gaccgggatc acaatcccca
     8521 gctctgccgc tactctgctg aaatgacgca ctgcaaggtt ttcctctgca gtctgcgcat
     8581 attcataata ctcgtatctg cgctcctggc agaaataggg ccgttcaaaa agctccggca
     8641 gaagaacaat ctcagctccc tttgctgctg cctgacgcac cagttcctct gcatgggcaa
     8701 tatttttctc cacactttta ctgcatctca tctgaactgc tgccactgtt acatttctca
     8761 tcctgtctgt tcctcctgct cctgtttaca taagtaagtt ttttcataac tttcaggtaa
     8821 taaccctcaa acacatgact ctcaaagttt ttctgcatca aggtcagata tttttccggg
     8881 aatctgctgg gtgatacagt gaatatttcc accgccaaca atgatggctc tggcatcaat
     8941 gggataaatc cttctttcag gaaaacactt ctgcagaatc tccactgccc ttttgtcatt
     9001 ttcatcccca aactgcggaa ggatgatccc tccattggaa atatagaaat tcacgtaact
     9061 ggcagccatc cgttctcctg cttcccgttc gtcttctccc tcttcaaaca caaaaccatc
     9121 cacatcttcc cgggtaaggc agaccggttt ctgaggaatc ggaagcttat gaatcttaaa
     9181 ttttctgcct tttgcatctg tttcctgttc cagcaccttc agatcagcca gagacatggc
     9241 atactgcgga tctgtctcat cctctgtcca tgcaagcaca acctctccgg gccttacaaa
     9301 agcgcacacg ttatccacat gctcattggt ttcatcctga tagattccac atggaagcca
     9361 gataatcttg tggacaccga gccagtactt caactgttcc tctatctgtt ccctgctcat
     9421 ctgaggattg cgtccctgac tcagaagaca ggcctctgta acgatcagag tcccctctcc
     9481 gtcagaatgg atggaaccgc cctcaagcac aaaaggtctg gcatccagac atggacaacc
     9541 aagagtcctg cagataaagg cagccaccct gtcgtccttc tcccagttcc ggtaaagccc
     9601 gtcaaagtct cctccccagg cattaaactg ccagtcaact ccacagactg cccctttctc
     9661 atccagaacc atggttgctc ccacatctct ggcccaggcg tcatctgtct cgcattccag
     9721 taaagtcaca ccggaaacat ttccaagctg attctttgca ttctccatct gagctttgga
     9781 aaccagcata tatacctttt cgctctctcc aatagcctct gcaactttca caaatgcttt
     9841 ctgcgcttcc cttgccccat aattccagga accgggacgt tccggccaga tcatcacaca
     9901 tccctcatga ggctcaaatt ctccgggcat acgatatttt gttctgttct tctctgtaac
     9961 ttccatgtct gtctcctttt ctctgatagc caggcagata tcaggaaagc cggctcttaa
    10021 agtcttcgta tccgaaatgt ctgataacct cacactctcc gtcctcatgc ataaccgcaa
    10081 tatccggcag cggcataccg ttaaatgtat tattcttcac catagaataa atcgccatat
    10141 ccataaaata cagcttgtcc ccgatccgga tctctctgtc aaaggaataa tctccgatca
    10201 catctcctgc caggcaggtg caggaagata agcggtaggt atatgccttc tcccctgctt
    10261 ccccgctgtc cttaagaggt ggacggtagg gcatctccag cacatccggc atatggcagg
    10321 ccgcagaagc atccagaacc aacgttctga ttccattctc cacaatgtcc ataacctctg
    10381 tcaccagata tcctgcattc agggcgacag cctccccggg ctccagataa atatccagat
    10441 cataggtttc tttcatatgc tgaatacatt tttccagtcg ctttacatca taatcctctc
    10501 tggtaatatg atgtccgccg cccatattca gccaggaaac ctcagacaga aattctccaa
    10561 acttctcctc tatcacctgc aatgttttct ccaggtcatc cgcattctgt tcacagagcg
    10621 tatgaaaatg cagcccgtcg atccatttca gacattccac gtcaaagttc tctctggtaa
    10681 cccccagtct ggaacccggc gcacagggat catagatcgc atgatccccc tgagtggagc
    10741 attccggatt aatacggagt cccagactgg ctctggtaca cacttcttta aatttcttaa
    10801 gctgtgctgt ggaattaaag ataatatggt cacagatccg gtccagttcc tccatatctt
    10861 ctgtgcggta agcaggggaa aaaacatgat tctctttccc catctcttca tgtccaagcc
    10921 ttgcctcaaa cagaccgctg gcagtggtac ctgccagata ttttccgatc atgggataca
    10981 gggcaaagcc ggaaaacgct ttctgcgcca gaaggatctt acacccggta tcctcctgga
    11041 cttttttcaa aatctccaga ttctcccgca tcttcttctc atcgatcaca tagcagggag
    11101 tttgcagttg atcaatcttc attggctttc cagaccttta ccagttcagg atcttcgcag
    11161 actttccatg gaagtcccca tttgttcagt gcttccatat atggatccgg atcaaattct
    11221 tccacattaa atacacccgg cttcttccac tgtccggtca ctaccatcat ggaaccgatc
    11281 atagccggaa cacctgttgt ataggagatt gcctgggatt ccacctcttt atagcattcc
    11341 tgatgatcac atacattata aatataaata cttttctctt ttccgtcctt aactcctgtg
    11401 aaaatacagc cgatatttgt ttttcccact gttctcgggc ccagagatgc aggatccggc
    11461 agaagagctt tcaaaaactg gatcggcacg atctcctgtc cgttaaattc cacaggtgcg
    11521 gtggaaagca tccctacatt ttccagacat ttcatatgtg tcagatagct ctgtccgaat
    11581 gtcataaaga aacggatcct ctgtactccc ggaatattct ttgccagtga ttcaatctct
    11641 tcatgatgaa gaagatacat atccttcttt cctacctcag ggaaatcata gacagattta
    11701 aattccatag gctctgtttc tacccaatgt ccgtcttccc agtaggaacc atttgcggaa
    11761 acctctcgaa gattgatctc cggattaaag tttgtggcaa aaggatatcc atgatcaccg
    11821 ccgttacagt ccagaatatc aatggtatga atttcatcaa aataatgctt cagggcatat
    11881 gcactgaata cactggtaac acccggatca aaaccggttc ccagaagagc agtcagtcct
    11941 gctttcttaa atttctcatc ataagcccac tgccaggaat aatcgaaata tgcagtaaag
    12001 cctttttctt tacatctctt ttcatagatt gcacgccatg tgggatcttc tgtatcctct
    12061 gcttcataat tggcagtatc aatataatct gcaccggctt ccagacatgc atccatgatg
    12121 gtaagatcct gatatggaag tgccacattc aggacagcat ccggcttata ggctctgatc
    12181 agttctgcga cctcttctgc attatccgca tctacctttg ctgtctcaat ttttgtcttc
    12241 gttgtacttt caatcttctc tttgagtgca tcgcattttt cctttgtcct gcttgcgatc
    12301 ataatctctg taaaaacatc gctgttctga cagcatttgc gaattgctac cgaagctacc
    12361 ccgccacatc cgattaccaa taatctgctc ataaactgtt ttcctcctct tccagtaaat
    12421 cttctacata ttttggaagc ataaatgctc ctctgtgaag gtttgttgta taataccatg
    12481 tttctatatt aagatcatca aacctctccg gcctgaaatc ttccagtgga tgatatttct
    12541 ttgatgcaaa tccaaaaagc cagtatcccg agggacaggt agggatatgt gcctgataaa
    12601 ccctgctcac cggaaatgac cggaaaacct ttctgtgcat ctttctgcat tccacctcat
    12661 cctcatcata aaaaggactt ccatgctgat aaaccatgat tccgtcatct ctgagagcct
    12721 tataacagct tccgtagaat tcctttgtaa aaagtccctc tgtatgtccc agcggatctg
    12781 tggaatcatt gatgatcagg tcatatccgg cctttttatt ccgcaggaac cgaagaccgt
    12841 cttcataata aatattgact ctctcatcct tcagtccctg ggcaatatcc ggaaacatct
    12901 ccgcacatac atctacaaac attttatcgg attctaccac atcaatgctc tcaatctgtg
    12961 gataatggat cagttctctg gcaactccac cgtcaccgcc gccgatgatc agaacatttt
    13021 ttacattggg atgtactgtc attggcacat gcgtgaccat ctcatcataa ataaattcat
    13081 ctttgtcaga aaatacgatc tcaccgtcca gagccacaaa tcttccaaat tcttcagact
    13141 caaacacatc gattctctga aattcacttt cccctgaaaa taactgtcgg ttaatccgga
    13201 cagaaagctt tacatttcct gtatggaact cagaatacca taattccatg atcagatacc
    13261 ccctttcagg acctgaagat gttccacctt cggatcctcc attccctgca tggaacagcc
    13321 tttgtctctt gcataaagaa tgtattctac aatttcctgt gtcaccattt ccccaggagc
    13381 aagaatcggg attcccggag gataacacat aacaaattca ccgctgatcc tgcctgccgc
    13441 ctgttccatg ggcagagatt ctttctccgc ataaaatgcc tgctgtggag acgccaccac
    13501 tgcaggtgcg atatattccc cggaaagcat acctgtgctg tccttcttat acagacgttc
    13561 aatatcagcc agtgccccta ccagtctctc aatatcctga agcctgtctc caatggaaat
    13621 gtaagccaga atattacaga tatctccaaa ctcgatctga atatcatatt catctctgag
    13681 aagatcataa acttcaatac ccgccagtcc atttcccagt gtataaatgg agagttttgt
    13741 aacatcaaaa tcaaaaacac tggttccatt gatcagatcc ataccatatg cataatagcc
    13801 gccgatctca ttgatctcct ctctggcata ctgcgccatc cctgcaacct tttcaaagga
    13861 ttcctctccc ctgagtgcca gatttcttct ggatatatcc agactggaca acagaagata
    13921 ggaagcactt gtggtctgag tcagattgat gatctggcgc actttctctg cattcatgct
    13981 cttattcaaa agcagcagcg aactctgtgt cagacttccg ccggatttgt gcatggaaac
    14041 tgccgccatg tcagcacctg ccgccattcc ggatacagga aggtttctgc cgaaataaag
    14101 atgggttcca tgagcctcgt ctgccagcac cttcattcct cttgcatgag ccttctttac
    14161 gatagtccgc agatctgaac agattccata ataggtaggg ttatttacaa gaaccgccac
    14221 cgcatccggg ttctcatcca tagccttctc cacctgactg acctccatgc caagggaaat
    14281 gcccagctgt gcattcacct ccgggtttac ataaaccgga attgcaccgc acagtaccag
    14341 ggcattgatg gcacttttat gtacatttcg cggcaggatg attttatccc ctgccttaca
    14401 gacagaaagg atcatactct gcactgcaga tgtggttcct cctaccataa gaaatgcatg
    14461 cgctgcgcca aaagcatctg ctgccagctc ctccgcttct ctgatcaccg aaaccgggtg
    14521 gcagagattg tccagcggct tcatagaatt aacatccagc cccacacatt tctctcccag
    14581 aagctgtgca agctccggat ttcctcttcc ccttttatgt cccggcacat caaagggaac
    14641 gactctcttc tttcggaaac gttccagtgc ttcatatatg ggcgcatgct gttgtctttc
    14701 ataatccatt tgacatgttc ctcttttcct gttgtcatgt accggcaaat acagttcaat
    14761 cattcagcaa ttgtatgctg atttaaaacc ggcacaatga ttcaattatt tctctatata
    14821 tttgctatat ctgcacaaaa aaagaagcag ataagttcat tcaccatctg cttctctcat
    14881 gatctataga atttctcagg ctctgtctct ctctctactg agcagatttc ccgtataaat
    14941 ccgtctgtat cctgcgcctg ttcccatatt ctgaaatatt catgactgct gtcgtcttca
    15001 atcgctggca aatatatgct atgctcttat tgaccgtttc acaagatgat gtgtgcttac
    15061 gcactgatta ttataaagta atcaacttat aaaatttgag cttctaactc aatcaataat
    15121 gtggtgtctc ccacccggca actgccccgc ctgtccgtat ggcttaacat tcagaaactg
    15181 tctctgaatg tgagcaaata tttgcatgaa aacgatagtg tcttttcata ctaaagatga
    15241 gaataacata ctttctgaac tgttgtcaat tccattttcc atattttgca caggctttac
    15301 cctcttttta tattttcttt atttatccgg aaaagctttg tttatttttt aacaattttt
    15361 ttcttgagaa aacacatttt cttccattac cagggattac gattcttttc tcctatcaat
    15421 ttgcacaact tttatccagt ttattctcat tttttgacgt ttcagcaaaa attttcttga
    15481 catttttttc tcaaaatgat atattgtact catcaattga aagaaccttc gagtactgac
    15541 ggaaagagtg gagtgcaaac cacgtgtagt cggaggtttg tgggagccga ccgtctgggc
    15601 agtatttgaa atattcagat actggccttt ttttataact ttcagggcag aaatcaggaa
    15661 tgtcagacgg accggccgat acttctttca attaataatt gttgctgatc acggaatgaa
    15721 cagtaacaga agtttttcat gttatgcgga gacgaaagga gaaaaacatt atgggattca
    15781 aatcagacat tgaaattgca caggaatgca agatgcttcc aattactcag attgcagaga
    15841 aagcaggtat tgacgacaaa tatctggagc agtacggaaa atacaaagca aaaatcgact
    15901 acaatcttct gaaagaaagc gataagaagg atggaaaatt aatcctcgtt acagctatca
    15961 acccaactcc agcaggagaa ggtaaaacta ctactactgt aggtcttgca gatggtatgc
    16021 agagacttgg caagagtgtt atggtagctc ttcgtgagcc atccttagga ccggtattcg
    16081 gtgttaaagg cggtgcagca ggcggcggat atgcacaggt tgttcctatg gaagatatta
    16141 accttcactt cacaggtgac ttccatgcca ttggcgcagc taacaactta ctggcagcta
    16201 tgatcgataa ccatatcttc cagggcaatg cattaaacat cgacccacgt aagatcacat
    16261 ggagaagatg tgtagatatg aatgaccgtc agcttcgtaa cgtagtagat ggtcttggcg
    16321 gaaagacaaa cggtatgcct cgtgaagacg gatacgacat cacagttgca tctgaaatca
    16381 tggcagttct ctgtctcgca agtgacatca aagacctgaa agaaagatta tccaagatca
    16441 tcatcggata tacatacggc aaagtttccg aacagaaacc tgtaacagca ggtgaccttc
    16501 acgcagaagg cgctatgaca gccctgttaa aagatgccct gaaaccaaac ctcgtacaga
    16561 ctctggaaca cgttcctgca atcgtacacg gcggaccatt cgcaaacatc gctcacggat
    16621 gtaactctgt aacagctaca aagatggcca tgaagcttgc tgattatgca atcacagaag
    16681 ctggtttcgg tgctgacctt ggtgctgaga aattccttga tatcaaatgc cgtatggctg
    16741 gcttaaaacc aagcgcagtt gtaatcgtag ctacagtacg tgccctgaaa tacaacggcg
    16801 gcgttgctaa ggctgacctt aacaatgaaa acctggaagc tcttgaaaaa ggtatcccga
    16861 acctgttaaa acacgtttcc aacatcaaaa acgtatacaa acttccatgt gttgttgcta
    16921 tcaacgcatt ccctacagat acaaaagcag agcttgactt tgtagaagct aaatgtaaag
    16981 aactgggcgt taacgttgct ctttctgaag tatgggcaaa aggcggcgaa ggcggaatca
    17041 aacttgcaga agaagttatc cgtcttgttg aagaaccaaa cgacttctcc tatgcatatg
    17101 aactggaagg ttctatcgaa gacaaactga accagatcgt tcagaaagta tatggcggta
    17161 agaaagtagt tctgacagct aacgctcaga aacaggcgaa acagttagaa gctcttggct
    17221 ttggcaactg cccgatctgt gtagctaaga cacagtacag cttaacagat gaccagacta
    17281 aactgggtgc tcctactgac ttcgaagtta cagtacgtaa cctgaagatt tccgcaggtg
    17341 caggattcat cgtagctctt acaggtgaga tcatgacaat gccaggtctt cctaaagttc
    17401 cggctgctga gagaatcgac gtagacgaga caggtaagat cacaggtctg ttctgatccg
    17461 gttgaaatca atcgaataat tcaaaaatat aaaaatcata tttatatatg atatgtgtcc
    17521 agacgatttt acaggcggga agattttccc gcctgttttt ttcttatttt tttataagat
    17581 aatcttttcc ggaaatacca ggttccgtca tatggatcgg atccagaatg cgattaagtt
    17641 catcctcgtc cataagcttt tctttcagaa tcagacttct tacagattcg cctgtcttaa
    17701 ttgccttttt tgcaatatcc gcagccttct gatatccaag atgggggctg attgcagtga
    17761 taatacctac actgttttct accagataac ggcatctttc ttcatttgcc gtaattccta
    17821 caatacaatt atccaccaat gtctggactg catagccaag agtatcgata gactggaaca
    17881 tgcaatagaa aataatcggc tcaaacgcat ttaattccag ctgaccagcc tctgcagcca
    17941 tggtaatggt aacatcatta ccaataatat taaaagcaac ctgattcact acttcaggaa
    18001 taaccggatt aactttacct ggcataatag aggaaccatt ctgttttgcc ggaagattaa
    18061 tctccccaaa accagtacgt ggaccggagg acatcagacg gagatcattt gacattttgg
    18121 aaagagttac cgcacatgct ttcacagcac cggaaacggc tacaaatgga tccagattct
    18181 gagtggaatc aatcagatca aaagcctgta taaagtccat tcccgatatt tcagtgagat
    18241 ttggaacaat tcttctcaga tagccctcat ctgcattaat tcctgttcca atagcagtac
    18301 ctcccatatt aagagtccgc atttcatcca ttgctttatc cattctgtgg atatcacgca
    18361 tgattgctac cgaatatgcc ttaaattcct gtcccagacg aatcggcact gcatcctgca
    18421 tctgtgtacg tcccattttg attacgtgat caaactctac cgctttttcg ttaagagcat
    18481 cgtagagacg aagaagctgt ttcttcagat tctgcagtag acgaagagaa gtcattttac
    18541 cggcagtagg aataacatca ttggtagact gtccacaatt cacatcatcg ttaggattta
    18601 taattgtata atcgcccttt tttcctccca gtatctcaat cgcgcgattt gcaattactt
    18661 cattggcatt catatttaaa gatgtgccag ctcctccctg aacaggatcc acaataaatt
    18721 cattatggaa ttttcctgaa acaatttcat cacatgcctg gacaatcgcc tgtgcttttt
    18781 tcttctcaag aagccccacc tcacaattgg ttatcgctgc tgcttttttt atgtatgcaa
    18841 gactgttaat aatttccgga tgcatattca gccccgtaat atggaaattt tcagccgcac
    18901 gtaaggattg tactccataa tatacatctt ccggaatatc ctttacacca atagaatctc
    18961 tttctacacg atagtctgtt tttttcatag ttattcgccc tcccatgtat ttgccctcat
    19021 tatatatctc tgctataata taatcaaata catatatttt tataaaatat atagtgttta
    19081 aattatatat cggaggagtt tatatgtttc agggaatgga atacatctat gaggtataca
    19141 aggaaaaaag cttttccaaa gctgctactg ctcttttcat ttcgcagcct tctttaagcg
    19201 ccaatgtaaa acgtgtggaa aaccgtattg gctatcctat ttttgatcga agtaccaaac
    19261 ctttacagtt aaccgaagtc ggaaaacatt atatacaggc tgttgaaaaa gtcatggata
    19321 ttgagaataa tctcgaaaac tacctactgg atctgggaaa tctcaaaaca ggaactctta
    19381 atgtaggtgg cagtaacttt ttttcttcgt ggattctgcc tccccttatt gctgattttt
    19441 cccaaaaatt cccccatgtt caaatttctc ttgtagaaga aagtacagca aagctatccc
    19501 agtttctcca ggccggaaag ttagatctgg taatcgataa ctgtatcctg gataaccaga
    19561 tttttgaaca ttatacctac cagaaagaac aacttcttct agcggttcca aaaaattatt
    19621 cagtaaataa cagactgcag aaatatcaga ttcctattga ggaaatccgg aacgggcagt
    19681 tccgttcttc tcatattcct tctgttccat taaacaaatt cgagaacgaa ccatttatta
    19741 ttcttcgttc agataacgat accggtaagc gtgcactgac catttgtcag gaaaatcact
    19801 tttcaccttc tgtagtattt cgcctggatc aacagatgac cgcctataat atcgcatgtt
    19861 tgggaatggg tatcactttc atcggggatc ttctgctctc cagagttcca acaaattcag
    19921 aacttgtttt ttataagctg cccggtcaga gcagtaaacg cactgtattt ttttactgga
    19981 agaaaggccg ctatatcagc agagccatgg aagaattcct caagctgccc ttttcctgat
    20041 atgccataca tatcaaaaac tgccgtctcc acagatttta cttgtgaaga cggcagcttt
    20101 tctttatcaa tagcttttta ttcgcatctc aggagatcac aggacaccgg agtataaaat
    20161 tctctctgaa agctctcaaa atcattacac tttccaagaa gccacatcaa ctttgcgact
    20221 attgcctccg ttgtcatatc gtatgcctga agaagatgat atctggacat tgccctaaat
    20281 ccaacctcat acaattctac atcacttccc tccagcatta cctgtgtagc aatcacaaca
    20341 atacattttt ttctgttaag acattccagt ttttccagaa aatttctttc atctgcaaac
    20401 ggaattccac caaccccata actttctata actactgctt cataatgatc actgatgtaa
    20461 tccaatatat ctggtgtgat tcccggaaca agcttcaaaa gaaatacttt gggcaccaaa
    20521 cgggaataaa agctggttgg accggagtca cctgatatat ctacatagcg aattactctg
    20581 tcattatcta taaatgccac aatgggataa ttgatactgt caaaagcgtt aaaactcttg
    20641 gaacgtactt ttctggcgcg tgttcccagt attacttctc cgttaaatat caaaaaaaca
    20701 ccatttacat tctcttcaca tgcaaagcga aagctatctc ttagattttt gcgggcatct
    20761 gtaaccgttt taaccaaagg tttttgtgct cctgtgatta caaccggctt atgaggattt
    20821 tgaatcatat atgaaagagc tgctgctgta tatgccatcg tatccgtacc atgggtgata
    20881 acaaatccat cataacagtc aaaacgctct tctatcgcct gaacgatcat ttgccagtgt
    20941 tccggttgaa tattagtact gtctacgttc agcagagaca gtatttctac ctggcagaaa
    21001 tctgttatgc cagacagact ttctctaagt tcttcttccg aaattcccgg acgcagtccc
    21061 tgatcagttt ctacagatgc aattgtacct cctgtcaata tcaataaaat acgcttcatt
    21121 ttttcaatcc tgaaacaagc ttttcatcca cggctgcatc tggtgtcatt ttataaatgg
    21181 caatataaac gataaaggaa attaccattg caaccagacc tgacggtaaa tctaaaggaa
    21241 gagttatctt atactgaaat acaaatccta agattgctcc tacagcaaaa gagattaccc
    21301 ccgcccagcg gaaatttgga tgtttattca aaagttccat attgtatttg tctttattct
    21361 ttcttccaac tacaaaataa tctgcaagga tcggcgcaca taatggcgga gccatagatc
    21421 ccagaatatt aatgaaattt gcaaaaaaca gctgataaaa tgcaaatgaa ccaagaacag
    21481 ttcctgtaac tcctgcaata ataaccagtt tttttctgga aacattgatt ccaaatgcat
    21541 tcaaagacgg gcccgtatac agagcattgc aataaagttc actattgtct gttgtccaga
    21601 gagctgttgt ccataccaca acacctaaaa tcgcaacaat aaagttcacg ccaagcatcc
    21661 aaagtacata attaaaattg ccaatatata ctgtgccaat atatcctaca atatttaaaa
    21721 taggattagt aagaataaag catgcagctg cacatcccca gactgctttt gtgctcttat
    21781 tgaaacggaa catgtcaacg cccataaccg cacctgcaat ccagcttccc actactgcag
    21841 taattgcttc tcccatgcca agtccgtgaa gtttatttgc tttatccaaa aagccaccaa
    21901 cgccgccaca ctgaactaca taaataattc ctactacaac agctacgatc agaatcaatg
    21961 gagcaaaaac atctgatact ttttctattg ctcccattcc cttcactgct gtaaaagtga
    22021 aaaccagtcc ccagaaaacg caggcgatta ctacttccag tgtaataggt gctactccgg
    22081 aaaatccgta ttttgatggg tcaaatacaa tcactccagt cggattgccg atgaatgctc
    22141 cccatatatc accaatcatt ccaagaatac ttgagaacca ccctaaagtc agcaatgcca
    22201 ttacagccat tggtatagca cttcccttat atccataaga aaaacgtgca agcagagaaa
    22261 gatttaaccc tgttttctgt gcgacaatcc caaggaaaca tgtaaccaga tacagtgcac
    22321 ccataccaag aataatagcc atcattgcct gtgaaggtgg cataccgcct gttccaccgt
    22381 aaccgcctaa agttccgcca atgatcagac cggttactgc atatccaaaa ccgatccata
    22441 ccatgaactg gcttcgggtc gaacgacgtg ccgacatcgg aactggttcc agcataaatt
    22501 ccccatcatt ttccggtata tctacagtag tgttgttttt ttcttccata gctttctgtt
    22561 cctttccctt tttaatccat tcattcttta cctttccaag gagcctccat ttatgcccgc
    22621 gcaaacgtat accagatgta tatcacagaa atacatctgc gtcaataatt ttctaaattt
    22681 tccacaaaaa ccgtcgaaag taacaatctt tttctatgat ttttgttagt attctggtga
    22741 tatacgtagt tgcaagttac tgatattaca tttataatgt gtttaaattc atttatttca
    22801 ttctttatct tttattgagg agcgtccata tatgatacca aacgttaata aaaaaaattt
    22861 ttctactaca gaggccattc tgcaacagct tcgaaatgat attaataatc tacactataa
    22921 tgatcagttc attacagaag cagaagtctc atcccgtttt caagtaagca gaacacctgc
    22981 aagggaagca ctgaatatat tgtgtcagga gggtatcctt gaaaaaatcc ctcgaaaggg
    23041 ttatctgatc cgtaagctgt ctctttcaga gcttcaggag ctatgccagt accgttctat
    23101 tcttgaatgc ggagcagttg aatatgcaat ccgatttgca tctgattccg aactggaaaa
    23161 aatttatcag attgccagta aaaaaattga tttggatgat tctaattttt acactcatta
    23221 caatgagctt aatctggaat tccatcttt
//
