LOCUS       c00045_gnlPro..        14545 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IGCMKJBP_45.
ACCESSION   c00045_gnlPro..
VERSION     c00045_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 19:22:12
            Original ID  :: gnl|Prokka|IGCMKJBP_45
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14545
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14545
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[387:4545]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      388..4545
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..14545
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14545
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             2..121
                     /locus_tag="ctg45_1"
                     /transl_table=11
                     /translation="RTRGRSPYQNRTSQNIHCKQVILPDTILALLIAFAYIIT"
     CDS             388..1599
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4_9"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg45_2"
                     /sec_met_domain="Fer4_9 (E-value: 7.6e-11, bitscore: 32.9,
                     seeds: 61, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 6e-09, bitscore: 26.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 1.6e-15, bitscore: 47.6,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 1.6e-54, bitscore:
                     174.8, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 9.3e-29, bitscore: 90.3,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.4e-05, bitscore: 16.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LSQHIGAPATPVVAVGDKVLKGQKIAEAGGFVSSPIYASASGTVK
                     AIEPHRVAVGDMVNSIVIENDGAFEEVEYTPCEDVTALSKEEIVNKVKEAGVVGMGGAG
                     FPTHVKLSPKEPEKIEYVIANCAECEPYLTADYRRMLENPEELIGGMKIILQLFDHAKG
                     VLGIEDNKPDCIEKLTELVKDEPRIEVCPLQTKYPQGGERQLIYAVTGRAINSKMLPAD
                     AGCIVDNVETIIAVYRAVKLGRPVTNRISTITGDAIANPGNFLYSIGTSYAELVEAAGG
                     FKTQPEKIISGGPMMGFAMFSLDIPTTKTSSSLLCLSKDEVSKVEPSACINCGRCVEAC
                     PEQLIPSRLAKFSNNGLAEAFESWHGLECVECGSCSFVCPARRQLAQSIKTMKKQVLAA
                     KRKK"
     CDS             1632..2597
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg45_3"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 5.3e-119,
                     bitscore: 387.6, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VSDLYHVSSSPHVRAKDTTSRIMLYVIIALLPTSLFGIYNFGYKA
                     LVLILVTIASCVASEWVFNKIVHKKQTIDDLSAVVTGLLLALNLPATLPWWEAVIGGVF
                     AIVVVKCLFGGLGQNFMNPALGARCFLLIAFAADMTKFGITKNGIEVYSSVTPLAAMRN
                     GEAVNTMDMLIGRTAGTIGETSAIAILIGAIFLILMGVINLRIPASYIITFAVFMLLFG
                     GHGFDGSYLTAQLCGGGLMLGAFFMATDYVTSPITPMGQIIFGICCGILTGLFRCFGAN
                     AEGVSFAIILSNILVPLIEKHTVPMAFGQVKEAKKQEGGK"
     CDS             2600..3208
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FMN_bind"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg45_4"
                     /sec_met_domain="FMN_bind (E-value: 2e-20, bitscore: 64.0,
                     seeds: 891, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKIVHDALVLFAFTVVLGLILGVVYGITKGPIDQVNYEKTQSA
                     YKQVFEDADSFEEYADFDTAAAEDLMAQNGYSDDIEAVNTALDASGNPLGYVLTVTAKD
                     GSQGSITFSVGIQNDGTVNGYSITSISETPGLGMKAQEEPFYSQFEGKNVDSFTVVKST
                     PSADNEIEAISGSTITSKAMANGVNACLTYFHSVLEGGN"
     CDS             3212..3934
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg45_5"
                     /sec_met_domain="Rnf-Nqr (E-value: 1.1e-69, bitscore:
                     224.7, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKNVERLYNGLIKENPTFVLMLGMCPTLAVTSSAINGLGMGLST
                     TVVLVLSNMLISAFRKVIPDGVRMPAYIVIVASLVTVVQFIMQAYTPSLSESLGVYIPL
                     IVVNCIILGRAESYASKNPVVPSLFDGLGMGLGFTMGLTLIGLFRELLGAGQIFGFQIL
                     SLSWFTPITIFVMAPGAFLVLACLVAVMKIVREKMAAKGKPLAEPSGCITGDCAGCSMS
                     AACTGKKPAAEAPAEKAE"
     CDS             3949..4545
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg45_6"
                     /sec_met_domain="Rnf-Nqr (E-value: 2.4e-65, bitscore:
                     210.5, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTLLLIAIGSAIVNNVVLSQFLGICPFLGVSKKTETAAGMGGAV
                     VFVITISSFVTALIYKYILANSYLMSKGIDLTYLQTIVFILVIAALVQFVEMFLKKSMP
                     ALYQSLGVYLPLITTNCAVLGVALTNVTKEYGILESVVNGFATAFGFLIAIVLMAGVRE
                     KIEYNDIPKPFQGTAIVLISACLMSIAFMGFSGMI"
     CDS             complement(4685..5260)
                     /locus_tag="ctg45_7"
                     /transl_table=11
                     /translation="MNCILRAVLLTQMTSDTSYGTCLHDILALILGAALYNVLCLVRNK
                     LDQMLRTCSNTFSTCLTYFLVNLRNAVHDMNRIKRTSLYTATVSKASVITGLRSAVRHE
                     CHGCTVLVAGILVIASCLLTGSRTLYKCYLALAFLGCHTHDLTDLGCNRRAADRTLIDR
                     SLALCDCCCQTGTTGITTATTVISRKHT"
     CDS             complement(5471..6523)
                     /locus_tag="ctg45_8"
                     /transl_table=11
                     /translation="MEIFMMRKKKVLSCLLVPLLSANLLLSGCSRTADEPVTKSGFYFN
                     TVISVSIYEKGSEELLDDCFALAQKYEGYFSNTIPDSDISKINDAGGAPVTVHDETIEL
                     LKTGISYGDLSGGKFDITIGRLSDLWDISTKALLDQTDVSMIPSDTDIQAALATVDYRE
                     IQIDGNTVTLQNPDARIDLGGIAKGYIADQMKAYLNQKGITSGYINLGGNVLALGAKTD
                     GSAYTIGIQRPFGEENEAIASVSITDQTVVSSGVYERYFEVDGTRYHHILDTATGYPYD
                     NGLLEVTIITGASVDGDGLSTTCFSLGLEDGMALVESLDATEAIFITDDYEVHTSSGMG
                     TVIPYEILED"
     CDS             6690..7541
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AA_kinase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg45_9"
                     /sec_met_domain="AA_kinase (E-value: 8.7e-44, bitscore:
                     140.6, seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEQKHFHFNEKKRVVVKIGSSSLNYGETGNLNFTKLEHLVRELCN
                     LRNRGMDVCLVSSGAIAVGRQTLGMDERPKDISTKQACAAVGQARLMMIYQRLFAEYNQ
                     VAGQVLMTKNTMVNPVSRENAKNTFDELFRLGAIPIVNENDTVSTYEMQFGDNDTLSAI
                     VASLIGADLLILLSDIDGLFTDDPHKNPDAKLIEVVEEMDASIYGMAKSSTGSDVGTGG
                     MATKLTAAKIATLSGTDMIIANGRDVCILHHIFDDSFKGTIFQAKKKESFRIEDFILET
                     IG"
     CDS             7563..7787
                     /locus_tag="ctg45_10"
                     /transl_table=11
                     /translation="MNQEQIDRINALYRKSKAEGLTEEEKKEQALLRKQYVADVKKNLA
                     AQLNNIDMVNPDGSVENLGDKYGKKTGLS"
     CDS             7762..8406
                     /locus_tag="ctg45_11"
                     /transl_table=11
                     /translation="MEKRQDFPDAALTQEKARQQIRARHKAWRMELPQEEVQEKSRKIC
                     ERLAASDWYHNSAVIYGYYPLGAEADCLPFLAQALSDGKTVALPVTSKERLQRDCGQVK
                     RMQDTHRMEFYRIRELSRVREGAFHVMEPDESCKRIGGEDAVVLVPGLVFDRKGNRYGY
                     GGGYYDRYFARFPKLSRMAVAFEGQIEEQLAVLPTDVRMHRIYTEEREYRI"
     CDS             8714..9709
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg45_12"
                     /sec_met_domain="Aldedh (E-value: 3.7e-20, bitscore: 62.5,
                     seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKRPNGLMIGKKRVPLGVVGMIYEARPNVTVDAFALCFKTGNAV
                     ILKGGSDAISSNIVIVSVLQEVLEAHGIPRAAVSLIEDTSRETAAAFMKMNEYVDVLIP
                     RGGAGLIRAVVNQATIPVIETGTGNCHIYVDESADFDMAIRIILNAKTQRIGVCNACES
                     LVIHEKIVDAFMPKLAAALQQKDVVIYADEKSLAAAERREAANDGDLKKELLSAATEED
                     WGREYLDYMISVKTVSSLDEAIAHINRYNTGHSEAIITENYTNAQRFLDEIDAACVYVN
                     ASTRFSDGFEFGFGAEIGISTQKLHARGPMGLDALTSTKYIIYGNGQTRP"
     CDS             9725..11188
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Radical_SAM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg45_13"
                     /sec_met_domain="Radical_SAM (E-value: 2e-36, bitscore:
                     116.6, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKKIDIEIIDKKQIPQSEPERQYYFMDIAKNYVEQLAAKKGSPL
                     TFHVTTFGCQMNARDSEKLVGILERIGYVETDTEEADFVIYNTCTVRENANNKVYGRLG
                     VLQNYKKKNPHMLIGLCGCMMQETVVVEKLKESYRFVDLIFGTHNIYKFAELIVTAMES
                     DSMTIDIWKDTDQIVEDLPVERKYSFKSGVNIMFGCNNFCSYCIVPYVRGRERSREPKE
                     IIREIEQLVADGVVEVMLLGQNVNSYGKNLKEPVTFAQLLEEVEKIEGLERIRFMTSHP
                     KDLSDELIEVMGRSKKICKHLHLPLQSGSSRILKIMNRRYDKEHYLELVDKIRAAVPDI
                     ALTTDIIVGFPGETEEDFEETMDVVRKVRYDSAFTFIYSKRTGTPAASMEEQVPEDVIK
                     ARFDRLLKEVQKISAEKAGALTGQTLPVLIEEQNEQDASLVTGRLSNNSVVHLPGTADM
                     IGKILDVKLTECRGFYYLGERADGKGQTV"
     CDS             11212..11571
                     /locus_tag="ctg45_14"
                     /transl_table=11
                     /translation="VIFLAILLAVVTVFLVVYERTGTRADAGACVRVTVDGSVYGIYAL
                     GEEQEIPIVQDGVTTNVLTIRDGRADMTEADCPDKLCVHQKAISKNHEMIVCLPNKVVV
                     EVTGSEENGFDSIAR"
     CDS             11561..12055
                     /locus_tag="ctg45_15"
                     /transl_table=11
                     /translation="LRDKVAYLGVFLALALICSYVESLIPFYFGIPGVKLGLTNIVVVL
                     MLYCVGTKEAFAISMLRIVLAGFLFGNLFSILYSLAGGMFSFLVMYLLKRTGKLGVLPV
                     SVAGGMSHNIGQIAVAAFVVENINIFYYLPVLFVAGIVTGLLIGVAAQEIILRIGGRLK
                     R"
     CDS             12069..12680
                     /locus_tag="ctg45_16"
                     /transl_table=11
                     /translation="VYAYIKGVLADVEEESVVVEAGGIGYRIYTTGQTFDYLPAVGEEV
                     KLYTYLNVREDAMILYGFLTKDDLRVFKLLIGVNGIGPKGALAVLSVMTTDDLRFAVLG
                     DDAKAIAKAPGIGAKTAQRVILELKDKLSLEEAFELKSEHVSRQNENGSSGVKNEAVQA
                     LVALGYASSEALKALNGIEITDDMDVETLLKAALKNMAFL"
     CDS             12720..13718
                     /locus_tag="ctg45_17"
                     /transl_table=11
                     /translation="MEKRVISTQVQEEDLKIEKSLRPQTLDDYIGQQKAKENLKIYIEA
                     AKARGESLDHVLFYGPPGLGKTTLAGIIANEMGTHMKVTSGPAIGKPGEMAAILSNLQE
                     GDVLFVDEIHRLNRQVEEVLYPAMEDYAIDIMLGKGATARSIRLDLPKFTLVGATTRAG
                     LLSAPLRDRFGVVHHLEFYTVEELKTIILHSALTLGVEIDEEGAYEMARRSRGTPRLAN
                     RLLKRVRDFAQVKYDGRISKEVASFALDLLEVDKMGLDQNDRNILMTMIGKFAGGPVGL
                     DTLAAAIGEDAGTIEDVYEPYLVKNGLINRTPKGRVVTELAYQHLGIEHSV"
     CDS             13797..14237
                     /locus_tag="ctg45_18"
                     /transl_table=11
                     /translation="MAEKTSAEVIIGGKVYTLSGYEGEEYLQKVATYINNKLGEFQGME
                     ELRHLSGDMKATLLQLNIADDYFKAKTQVEKLEREIEQKEKEIYDLKHDLISNQIKAES
                     DEKARKELEEQNKELLINKAKLEASLEDALLGKVTEKDKTEE"
ORIGIN
        1 ccggactcgc gggcgttcgc cctatcaaaa tcgtaccagc caaaatatac actgcaagca
       61 ggtaattttg ccagatacga ttttggcact gctcattgcc ttcgcgtaca ttataacata
      121 aatgtggaaa aaatattgtg aattctttgt caataggttc gtgaaaaaat acaataaatt
      181 gctacaattt ccgagtgatt gtgctataat ctacacgagg gtattctatg acttttggca
      241 tagaatataa tatagataag agaaagtggg gcacgagaaa tgggttctaa gacatttaaa
      301 ggcggcgtcc atccttatga aggaaaggaa ctggcaaagg atcagccgat cgtagaagtt
      361 ctacctaagg gtgatctggt atacccgttg tcacagcata tcggtgcacc ggcgactccg
      421 gtggtagcgg ttggtgacaa ggtgctgaaa ggacagaaga tcgcagaggc aggtggcttt
      481 gtgtcatccc cgatctatgc gtcggcatcc ggtacagtaa aggcaatcga accgcaccgt
      541 gtggcagtcg gtgacatggt gaattccatc gtcattgaga acgacggggc gtttgaagag
      601 gtggagtaca cgccgtgtga agacgtgacg gctctctcca aggaggagat tgtcaataag
      661 gtaaaagagg caggcgttgt cggcatgggc ggtgcaggtt tcccgacaca tgtgaagctg
      721 tctccgaaag agccggaaaa gattgaatat gtaattgcaa actgcgcaga gtgtgagccg
      781 tatctgacgg cggactaccg cagaatgctc gaaaatccag aagagctgat cggtggaatg
      841 aagatcattc tccagctgtt cgatcatgcg aagggtgttc tcggcatcga ggacaacaag
      901 ccggattgta ttgaaaagct gacagagctt gtcaaggatg aaccgagaat tgaggtctgt
      961 cctttacaga ccaagtaccc gcagggtggt gagcgtcagc tcatttatgc agtgacaggc
     1021 cgcgccatca attccaagat gcttccggca gatgcaggat gtatcgtgga taatgtggag
     1081 accatcattg ctgtttaccg tgcggtaaag cttggcagac cggtaaccaa tcgtatttct
     1141 acgattacag gcgatgccat tgccaacccg ggcaacttct tatacagcat cggtaccagc
     1201 tatgcagaac tggtggaggc tgccggcgga tttaagacac agccggagaa gattatttcc
     1261 ggtggtccga tgatgggatt tgcaatgttt agcctggata ttcccacgac aaagacatct
     1321 tcctcactgc tttgcttaag caaggacgaa gtgtccaagg tggagccgtc cgcatgtatc
     1381 aactgcggcc gctgtgtgga agcatgcccg gagcagctga ttccgtcaag acttgccaag
     1441 ttttccaata acggtctggc tgaggcgttt gaatcctggc acggactcga gtgcgtggag
     1501 tgcggaagct gcagttttgt atgccctgca cgcagacagc tcgcacagtc cattaagacg
     1561 atgaaaaagc aggtacttgc tgcaaaacgc aaaaaataat tcaaaaaaca agaagagaga
     1621 ggtggattat cgtgagtgat ttatatcatg tttcatcatc accacacgtt cgtgccaaag
     1681 ataccacaag ccgtattatg ctgtatgtga ttattgcatt gcttccgaca agcctgttcg
     1741 gtatttacaa tttcggatat aaggcattgg ttctgattct ggtaacgatc gcaagctgtg
     1801 tggcatcaga gtgggtattt aataagattg tacataaaaa gcagacgatc gatgacctga
     1861 gcgccgttgt aacgggactg cttctggcat tgaaccttcc ggcaaccctt ccgtggtggg
     1921 aggcggtaat cggcggtgtg tttgcaatcg tggttgtaaa atgtctgttt ggcggactgg
     1981 gacagaattt catgaacccg gcgctgggcg caagatgctt ccttttgatt gcatttgctg
     2041 ctgatatgac aaagttcggc atcacaaaga acggtattga agtgtattcc agcgtaacac
     2101 cgcttgctgc catgcgtaac ggtgaggcgg tcaatacgat ggatatgctg atcggacgca
     2161 ccgcaggtac cattggtgag acatctgcga tcgctatcct gatcggagct attttcctga
     2221 ttctgatggg tgtgatcaac cttcgcatcc cggcatctta cattattaca tttgctgtat
     2281 tcatgctttt attcggcggt catggatttg acggcagcta tcttaccgca cagctttgcg
     2341 gcggcggtct gatgctcggc gcattcttca tggcaacgga ttatgtgaca tccccgatta
     2401 caccgatggg gcagatcatc tttggtatct gctgcggtat cctgaccgga ttgttccgct
     2461 gcttcggcgc gaatgcagag ggtgtttcct tcgccatcat cttaagcaat atccttgtgc
     2521 cgcttattga gaagcacacg gtgccgatgg cattcggtca ggtgaaggaa gcgaagaagc
     2581 aggaaggagg caaatagaaa tgaacaagaa gattgtacat gacgcattgg ttttatttgc
     2641 ttttactgtt gtattaggtc tgatcctcgg cgtggtctac ggcattacca aaggcccgat
     2701 cgaccaggta aattatgaga agacacagtc cgcttacaag caggtatttg aggatgcgga
     2761 ttcctttgag gagtacgctg atttcgacac cgctgcagcg gaagatctta tggcgcagaa
     2821 tggatattct gacgatatcg aggctgtcaa cacagcactt gacgcttccg gcaatccgct
     2881 cggctatgtg cttaccgtaa cggcgaagga cggaagccag ggcagcatta cattctctgt
     2941 cggcatccag aatgacggta cggtcaacgg ttattccatc acaagtattt ccgagacacc
     3001 gggacttggt atgaaagcac aggaagagcc gttctacagc cagtttgagg gcaagaacgt
     3061 agactccttt acggttgtga agtcgacacc gtctgcggac aatgagatcg aggcaatttc
     3121 cggttccacc attacttcca aggcgatggc gaacggtgtg aatgcctgcc ttacatactt
     3181 ccacagcgta ttagaaggag gtaactaatc aatgaacaag aatgtagaac gtttatataa
     3241 tggactcatt aaggaaaatc ctactttcgt tctgatgctt ggtatgtgtc cgacacttgc
     3301 tgtcacatcc tccgcaatca acggacttgg tatgggactt tccacaacag tggtactggt
     3361 actttccaat atgctgattt ccgcattccg taaggtgatt ccggacggtg tgcgcatgcc
     3421 ggcatacatt gttatcgttg catcgctggt aacagtggtg cagtttatca tgcaggcgta
     3481 taccccgagc ctctccgagt cgctgggtgt gtatatcccg ttaatcgttg taaactgtat
     3541 tatcctcggc cgtgctgaga gctatgcttc caagaatccg gtagttccgt ctcttttcga
     3601 tggacttggt atgggacttg gatttacgat gggtcttacc ctgatcggac tgttccgtga
     3661 gcttctgggc gcaggtcaga tctttggttt ccagattctg tccttaagct ggttcacacc
     3721 gatcaccatc tttgttatgg caccgggagc attcctagta ctggcatgtc tggtagctgt
     3781 gatgaagatc gtccgtgaga agatggcagc caagggcaag ccgcttgccg agccgtccgg
     3841 atgtatcacc ggagactgtg caggatgcag tatgtctgct gcatgcaccg gtaagaaacc
     3901 ggcagcggaa gctccggcag aaaaagcaga ataggaggat agatacggat gaaaacatta
     3961 cttttaattg caatcggctc tgccattgtc aataacgttg tattaagtca gttccttggt
     4021 atctgtccgt ttttaggcgt ttccaagaaa acagagaccg ctgccggaat gggtggcgca
     4081 gttgtattcg ttatcacgat ctcttcgttc gtgacagcgc tgatctacaa atatatcctt
     4141 gccaacagct atctgatgag caagggcatt gaccttacct acctgcagac gattgtattt
     4201 attcttgtaa ttgctgcact ggtacagttc gttgagatgt tcttgaagaa gtccatgccg
     4261 gcattatacc agagccttgg tgtatacctt ccgctgatta cgacaaactg tgccgttctc
     4321 ggtgttgcac tgacgaatgt taccaaggaa tacggtattt tggagagcgt ggtaaacggt
     4381 tttgcaaccg catttggttt cctgattgcg atcgttttaa tggcaggtgt gcgtgagaag
     4441 atcgagtaca atgatatccc gaagccgttt cagggtactg caatcgtatt gatttccgca
     4501 tgtctgatgt caatcgcatt catgggattc tcaggaatga tttaggagga aaaagaagat
     4561 gaacgttaca gcaattttat ttgcagcctt aatcgtgggc ggcgtaggta tcttgattgg
     4621 atttttcctt ggtatttccg gagaaaagtt caaggtagag gtagatgaaa aagaggaagc
     4681 aatcttaggt gtgcttccgg gaaataactg tggtggctgt ggttatgccg gttgttccgg
     4741 tctggcagca gcaatcgcaa agggcgaggc tccggtcaat cagtgtccgg tcggcggcgc
     4801 gccggttgca gccaagatcg gtgagatcat gggtgtggca gccgaggaag gcgagcgcaa
     4861 ggtagcattt gtaaagtgtg cgggaacctg tgagaaggca ggacgcgatt acgagtatac
     4921 cggcaacgag gactgtgcag ccatggcatt cgtgccgaac ggcggaccga agtcctgtaa
     4981 ttacggatgc cttggatacg gtagctgtgt aaaggcttgt ccgtttgatg cgattcatat
     5041 cgtggacggc attgcgcagg ttgacaagga agtatgtaag gcatgtggaa aatgtgttgc
     5101 tgcatgtccg aagcatctga tcgagcttgt tccttacaag gcaaagcaca ttgtacagtg
     5161 cagctccaag gataagggca aggatgtcat gaaggcatgt tccgtaggat gtatcggatg
     5221 tcatctgtgt gagaagaact gcccgaagga tgcagttcat gtcattgaca acgtggcata
     5281 cattgatcag gagaagtgtg tcggatgcgg tatctgtgca cagaagtgtc caaagaaaat
     5341 tattctgtaa gaatgatttt ctccgaaaat catcctgtaa gaatcgtttc ttggaatgaa
     5401 agtgtgaaat aaaaacaggc gtgaagaatt cgcggtaata agtacgaatt cttcacgcct
     5461 gttttgttgt ttaatcttcc agaatctcat agggaatgac ggttcccatg ccggagctgg
     5521 tgtgtacttc atagtcgtct gtgatgaaaa tagcttccgt agcatcaagg ctttcaacga
     5581 gcgccatacc gtcttccagc ccgagggaga aacaggtggt ggagagaccg tcgccgtcca
     5641 ccgatgcacc ggtgatgatc gtgacctcaa ggagcccgtt atcgtaaggg taaccggtcg
     5701 cggtgtccag gatatggtga taacgcgtcc catctacttc aaaatagcgt tcgtagacgc
     5761 cggaggatac gacggtctga tcggtgatgg agacggaggc aatcgcttcg ttttcctcac
     5821 caaacggacg ctgtatgccg atggtgtatg ccgaaccgtc cgtcttcgcg ccgagcgcaa
     5881 gcacatttcc gccgagattg atgtaaccgg aagtaattcc cttctggttc aggtaggctt
     5941 tcatctgatc cgcgatatag cctttggcga tgccgcccag atcaatcctg gcatcgggat
     6001 tttgcagagt cactgtgttg ccgtcaatct gaatctcccg gtaatccact gtggcaagag
     6061 ccgcctgaat gtccgtgtcg gaggggatca tggagacatc ggtctgatca agcagcgctt
     6121 tggttgagat gtcccacaga tcggaaagcc gaccgatggt gatgtcgaat ttgccgccgc
     6181 ttaagtcgcc atatgagatg ccggttttaa gaagttcgat cgtctcgtcg tgtactgtca
     6241 cgggagcgcc gcccgcatcg ttgattttgg aaatatcgct gtctggaatc gtattggaaa
     6301 aatatccctc gtacttttgc gcaagggcaa aacagtcatc gagcagttcc tcgctccctt
     6361 tttcatagat cgagaccgag atgacggtgt taaaataaaa tcctgacttg gtaaccggtt
     6421 cgtccgccgt gcggctgcag ccggagagca gcagatttgc agagagcagg ggaaccagaa
     6481 gacaggagag taccttcttt tttctcatca taaaaatctc catttctgat gtttcccatc
     6541 caatgtacca taaactttct gttcatacaa tgtgaaaaca tcaatttgcc attttgatga
     6601 agatatgata gagtaataca gtatgagact ctatgcccat ttgggatgaa tgattggaaa
     6661 atgttacata taaaggggac gttagacaga tggaacaaaa gcattttcat tttaatgaga
     6721 aaaagagagt tgtagtcaag atcggatctt cctcattgaa ttacggggag acaggcaatc
     6781 tgaattttac caagctggag catctggtaa gagaactctg caatctgcgg aaccgcggga
     6841 tggatgtgtg tctggtaagc tccggcgcga ttgccgtggg cagacagacg ctcggcatgg
     6901 atgagcggcc gaaggacatt tcgacaaagc aggcatgcgc ggcggtcggc caggcgcggc
     6961 tgatgatgat ctatcagcgg ctttttgcgg aatacaatca ggtggcaggg caggtgctga
     7021 tgacgaagaa cacgatggtg aaccctgtct cgagagagaa tgcgaagaat acgttcgacg
     7081 aattgttccg tcttggcgca atcccgattg tgaatgaaaa tgatacggtt tctacttatg
     7141 agatgcagtt tggcgacaac gacacgctct cggcaatcgt ggcttctctg atcggggcgg
     7201 atcttttgat cctgctctcg gatatcgatg ggctttttac cgacgatccg cacaagaatc
     7261 cggatgcaaa gctcattgaa gtggtggagg agatggatgc gtcaatctac ggcatggcga
     7321 aaagttcgac cggcagtgat gttggaaccg gcggcatggc gaccaaactg acagccgcaa
     7381 agattgcaac gctctcggga acagacatga ttattgcgaa cggcagggat gtctgcattc
     7441 tgcatcatat atttgatgat tcctttaagg gaaccatttt tcaggcaaag aagaaagaat
     7501 ctttccggat tgaagatttt attttggaga cgatcggtta agaatacagg aaaaggagta
     7561 ctatgaacca ggaacagatt gacagaatca atgcgttata tcgcaagtcg aaggcggaag
     7621 ggttgacgga ggaagaaaaa aaggagcagg cgctgctgcg caagcagtat gttgcggatg
     7681 tgaagaaaaa tctggcggcg cagcttaaca atatcgatat ggtgaatccg gacggttccg
     7741 tggagaacct tggagataag tatggaaaaa agacaggact ttcctgacgc agcgctgaca
     7801 caggagaagg cgcgtcagca gataagggcg cggcacaaag catggcggat ggaactgccg
     7861 caggaggaag tgcaggaaaa gagcagaaag atctgtgaga ggctggcggc gtctgactgg
     7921 tatcataaca gcgctgtcat ctacggctat tatccgctcg gcgcggaggc tgactgtctg
     7981 ccgtttctgg cacaggcact ttcggacggc aagacggtgg cgcttccggt tacatcaaaa
     8041 gagcggttgc agcgggactg cggccaggtg aagagaatgc aggacacaca ccggatggag
     8101 ttttaccgga tcagagagct ttccagggtg cgggagggcg cctttcatgt gatggagccg
     8161 gatgagagct gcaaacggat cgggggagag gatgcggtgg tgctggtgcc cggactggtc
     8221 tttgaccgta aggggaaccg gtacgggtat ggcggcggtt attatgaccg ctattttgca
     8281 aggtttccga agctgtcccg catggcggta gcgtttgaag ggcagatcga ggaacagctt
     8341 gcggtgcttc ccaccgacgt gcggatgcat cggatttata cggaggagcg ggaatatcgg
     8401 atctgacaga aaggatggaa aggatatgga actgacagaa ctttgtaaga gcgcaaaaga
     8461 agtgagcaga cagatcggca atctggacac gaatacgaag aacgaggtgt tgcgtgcagc
     8521 ggcagaggca attgtggcac atactgaaga gattatccgc gagaatgaga aggatctcgc
     8581 ccgcggcaga gagaatcata tgcccgaagg actgctggac cgtctgatgc tcaacccatc
     8641 ccggctggag cagatggcgg agggactgcg gcaggttgca gaactttctg atccgatcgg
     8701 cgaagtcctt tccatgaaga agcgcccgaa cggtcttatg atcggtaaaa agcgcgtccc
     8761 gctcggtgtg gtcgggatga tctatgaggc gagaccgaat gtgacggtgg atgcgtttgc
     8821 gctgtgtttt aagacgggca acgcagtgat cttaaaaggc ggcagtgacg ccatttcgtc
     8881 caatatcgtc attgtttcgg ttctgcagga agttttggag gcacatggca ttccgcgtgc
     8941 ggcagtatcg ctgattgaag atacaagccg ggagacggcg gctgcgttca tgaagatgaa
     9001 cgaatatgtg gatgtgctga ttccgcgcgg aggagcaggg ctgatccgcg ccgtcgtcaa
     9061 tcaggcgacg attcctgtga ttgagacggg aaccggcaac tgtcatatct atgtggatga
     9121 gagtgcggat ttcgatatgg caatccgtat tattttaaac gcaaagaccc agcggatcgg
     9181 tgtgtgcaat gcctgtgaat cactcgtgat ccatgagaaa atcgtggatg catttatgcc
     9241 aaagcttgcg gcggcactgc agcagaagga tgttgttatt tatgcggatg agaaaagtct
     9301 tgcagcggca gagcgccggg aggcggcaaa tgacggagac ctgaaaaagg aactgttgtc
     9361 ggcggcgacg gaggaagact ggggcaggga gtatctcgat tatatgatct ccgtgaagac
     9421 ggtgtcgtcc ctcgacgagg cgatcgcaca catcaaccgc tacaataccg ggcattcgga
     9481 ggcaatcatc acagaaaact acacgaacgc gcagcggttc ctggatgaga tcgatgctgc
     9541 ctgcgtctat gtcaacgcat cgacgcgttt ttcagacgga tttgaatttg gatttggcgc
     9601 ggagatcggc atcagtaccc agaagcttca tgcaagagga ccgatgggac tggatgcgct
     9661 gaccagcaca aaatatatta tatatggaaa cgggcagaca cgtccgtaga tggtaaggat
     9721 gaagatgaaa aagaaaatag acattgaaat aatcgataaa aagcagatcc cgcagagcga
     9781 gccggagcgt cagtattact ttatggacat tgctaaaaat tatgtggaac agctcgctgc
     9841 aaaaaaaggc agtccgctga cctttcatgt cacgacgttc ggctgccaga tgaacgcgcg
     9901 cgattctgag aagcttgtcg gtatcttaga gcgcatcggt tatgtggaga cggatacgga
     9961 ggaagcggat tttgttattt acaatacctg cacggtgcgt gaaaatgcaa ataacaaagt
    10021 ctacggaaga ctcggggtac tccagaatta taaaaagaaa aatccacata tgctgatcgg
    10081 actctgcggc tgcatgatgc aggagacggt agttgttgaa aaattaaaag aaagctaccg
    10141 ctttgtggat ctgatcttcg gaacacataa tatctacaaa tttgcagagc tgattgtgac
    10201 ggcgatggaa tcggattcca tgacgattga tatctggaag gacacggacc agatcgtgga
    10261 ggacctcccg gtagagcgga agtattcgtt taaatccggc gtcaatatca tgttcggatg
    10321 caataatttc tgcagctact gtatcgtacc gtatgtgcgc ggaagggagc gcagcaggga
    10381 gccgaaagag atcatccgtg agatcgaaca gctcgtggcg gacggcgttg tcgaggtcat
    10441 gctgctcgga cagaatgtca attcctacgg caagaatctg aaggagccgg tgacatttgc
    10501 gcagctttta gaggaagtgg agaagattga ggggttagag cgtatccgtt ttatgacctc
    10561 ccacccgaag gatctctcgg acgagctgat cgaggtgatg ggacgatcca aaaagatctg
    10621 caaacatctg cacctgccgt tacagtccgg gagcagccgg atcttaaaga tcatgaaccg
    10681 cagatatgat aaggaacatt atctggagct ggtggacaag atccgcgcgg cagtgccgga
    10741 cattgcgctg acgacggata ttatcgtggg attcccgggg gagacggagg aggacttcga
    10801 ggagacgatg gacgtggtgc gaaaagtgcg ttatgacagc gcgttcacgt ttatctattc
    10861 caaacgtacc gggacaccgg cggcatccat ggaagagcag gtgccggagg atgtgatcaa
    10921 ggcgcgtttt gaccgcctgc ttaaggaagt gcagaagatc tccgcagaaa aagcgggggc
    10981 gctgaccgga cagacgctgc cggtgctgat tgaggagcaa aacgagcagg atgcttcgct
    11041 tgtgacggga agactcagca ataactcggt ggtacatctg ccggggacag cggacatgat
    11101 cggaaagatt ctggatgtaa agctgaccga gtgccggggc ttttattacc ttggcgagcg
    11161 ggcagacgga aaaggtcaga cggtatgaaa aagcgaatca gcagaaacga tgtgattttt
    11221 cttgcaatac tgcttgccgt ggttacggta tttcttgtgg tctatgagcg gacgggaacg
    11281 cgcgcggatg cgggtgcctg tgtgcgcgtc accgtggacg gcagtgtgta cgggatctat
    11341 gcgctcgggg aggagcagga gataccgatt gtgcaggacg gcgtgacaac gaatgtcctg
    11401 acaatccgcg atggcagggc ggacatgacg gaggcggact gcccggacaa gctgtgtgtc
    11461 catcagaagg caatctctaa gaatcatgag atgattgtct gtttgccgaa caaagtggtt
    11521 gtggaggtga cgggaagtga agaaaacgga ttcgactcca ttgcgagata aggtggcgta
    11581 tctcggggtt tttcttgcgc ttgccttaat ctgcagttat gtggaatccc tgatcccgtt
    11641 ttatttcgga ataccggggg taaagctggg gctcaccaat attgtggtgg tactgatgct
    11701 gtactgtgtc ggcactaagg aggcgtttgc catctcgatg ctccggattg tactggcggg
    11761 ttttctgttc ggcaatctgt tcagtatctt atacagcctt gccggcggaa tgttcagctt
    11821 tctggtgatg tatcttttga aacggaccgg aaagctcggt gtgctgccgg tcagcgtcgc
    11881 gggcggaatg tcacacaaca ttggtcagat tgccgtggcg gcgtttgtgg tggagaatat
    11941 caacattttt tactatctgc cggtgctttt cgtggcaggc atcgttacgg gactgctgat
    12001 cggtgtggca gcccaggaga tcatactaag gattggcgga cggctgaaac gataaggagg
    12061 aaatacgtgt gtacgcatat ataaaaggcg tccttgcgga tgtggaagaa gagagcgtgg
    12121 ttgtggaggc aggcggaatc ggataccgga tctatacgac cgggcagacg tttgactatc
    12181 ttccggctgt gggagaggaa gtcaagctct atacgtatct gaatgtgcgc gaagatgcga
    12241 tgattctgta cgggtttttg acgaaggatg atctgcgtgt cttcaagctg ttaatcggcg
    12301 tcaacggtat cggcccgaag ggggcgctgg cggtgctgtc tgtgatgaca accgatgatc
    12361 tgcgatttgc ggtgcttggc gatgacgcga aggcgatcgc caaagcgccc ggaatcggtg
    12421 caaagacggc acagcgtgtg attttagaac tgaaggacaa gctgtcgctt gaggaggcgt
    12481 ttgaactcaa atccgagcat gtgagcagac agaacgagaa cggaagcagc ggtgtgaaga
    12541 atgaggcggt gcaggcgctt gtggcgctcg gctatgcctc ttcggaagcg ttaaaggcgt
    12601 taaacggcat tgagatcacg gatgatatgg atgtggaaac actgttaaaa gccgcgctta
    12661 agaatatggc attcctgtag taagggaagc ggcaaggcgg aagaaaggaa agctgggaca
    12721 tggagaagcg ggtcatatcc acgcaggtgc aggaagaaga tcttaagatc gagaaaagtc
    12781 tccggccgca gacgctggac gattatatcg gacagcagaa ggcaaaggaa aatttaaaaa
    12841 tatatatcga ggcggcaaag gcgagggggg aatctctcga ccatgtgctg ttctacggac
    12901 cgcccggact tggaaagacc acgctcgccg gaatcattgc caatgagatg ggaacacata
    12961 tgaaggtcac ttcgggacct gccatcggaa aaccggggga aatggcagcg atcctgagca
    13021 atctgcagga gggagatgtc ctctttgtcg acgagatcca ccggctgaac cgccaggtgg
    13081 aggaggtgct gtacccggca atggaggatt atgccattga tatcatgctt ggcaagggag
    13141 ccacagcgcg ctccatccgt ctggatctgc cgaagtttac cctggtggga gcgaccacgc
    13201 gcgcgggact tttgtcggca ccgttaagag accgttttgg cgtggtgcat catctggagt
    13261 tctacacggt ggaggagtta aaaacgatca tcctgcattc ggcattgaca cttggggtgg
    13321 agatcgatga ggaaggtgct tacgagatgg cgagacgctc gcgcggaacc ccgcgtctgg
    13381 cgaaccggct gttaaagcgc gtgcgcgatt tcgcgcaggt aaaatacgac ggccggattt
    13441 caaaggaggt agcgtccttt gcactggatc tgctggaggt tgacaagatg gggctcgatc
    13501 agaatgacag gaacattttg atgacgatga tcggaaaatt tgcgggcgga ccggtcgggc
    13561 tggacacgct ggcggcagcg atcggtgagg atgccggaac catcgaggac gtatatgaac
    13621 cgtatctggt aaagaacggg ctgatcaacc gcacgccgaa gggacgggtg gtgacagagc
    13681 tggcatacca gcatctggga atcgaacatt ccgtatagaa atagttgctt ttccttaaat
    13741 atgtcagtat aatatactat atattgtagc ggatacccga gtttggagga aatggtatgg
    13801 cagagaagac aagcgccgaa gtgatcatcg gtggaaaggt atacacactg agcggttatg
    13861 agggcgagga gtacctacag aaggttgcca cctatatcaa caataagctg ggcgagtttc
    13921 agggcatgga agagttaaga catctatccg gcgacatgaa ggcgacgctg ttgcagttga
    13981 atatcgcgga tgattatttt aaggcgaaaa cacaggtgga gaagcttgag cgtgagatcg
    14041 agcagaagga aaaggaaatc tacgatctca aacatgatct tatttccaat cagatcaagg
    14101 cagagagcga cgagaaagcc agaaaagagc tcgaggagca gaacaaggag cttttaatca
    14161 acaaggctaa gctggaggcg agtctcgagg atgcgctgct cggcaaagta acggaaaaag
    14221 ataaaacaga agaatagaca atacggggac gtaagagatt tgctttcgtc ccttattttc
    14281 atataacagg taagaaaaat gatgcagaaa agagaattgg agctgctggc tccggcggga
    14341 tcatacgaga cgtttgaggc ggtcatacgg gcgggggcgg acgcggtata tctgggcggc
    14401 agccattttg gagcccgcgc atatgcgaat aattttaatg aggaagaatt gctgcgtgcc
    14461 atcgactatg cacatatcca tggcagacag gtgtatctga cggtgaacac cctgttcaag
    14521 gaggaggaac tggaacaggg actct
//
