LOCUS       c00105_gnlPro..         8516 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IGCMKJBP_105.
ACCESSION   c00105_gnlPro..
VERSION     c00105_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 19:22:12
            Original ID  :: gnl|Prokka|IGCMKJBP_105
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 8516
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..8516
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[166:4450](-)"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      complement(167..4450)
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
     cand_cluster    1..8516
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /kind="single"
                     /product="Others_HGD_unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..8516
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Others_HGD_unassigned"
                     /region_number="1"
                     /rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1,
                     HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and
                     minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2,
                     AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF,
                     ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C,
                     Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and not (minimum(2,
                     [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /tool="gutsmash"
     CDS             complement(3..77)
                     /locus_tag="ctg105_1"
                     /transl_table=11
                     /translation="MEIQREIWFKKCGISNQPDVCIFDD"
     CDS             complement(167..4450)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: BcrAD_BadFG"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg105_2"
                     /sec_met_domain="HGD-D (E-value: 7.4e-61, bitscore: 195.3,
                     seeds: 370, tool: rule-based-clusters)"
                     /sec_met_domain="BcrAD_BadFG (E-value: 1.1e-38, bitscore:
                     121.9, seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENNTLHKLGIDIGSTTVKVAILDQEDHLLFSDYERHFANIQETL
                     SSLLQKAYDALGDFSVAPMITGSGGLTLAKHLGVPFVQEVIAVSTALQHYAPQTDVAIE
                     LGGEDAKIIYFEGGNVEQRMNGICAGGTGSFIDQMASLIQTDATGLNEYAKNYKAIYPI
                     AARCGVFAKTDIQPLINEGATREDLSASIFQAVVNQTISGLACGKPIRGHVAFLGGPLH
                     FLSELKAAFIRTLNLDDEHAITPENSHLFAAIGSALNYKPGETTTLVSLRDRLANGIKM
                     EFEVARMDPLFASQEEYDAFRARHDGHNVRSADFSTYEGNCYLGIDAGSTTTKIALVGE
                     DGSLLYSFYSNNNGSPLATAIRSIKEIYTLLPPKAKIVHSCSTGYGEALLKAALMLDDG
                     EVETVAHFYAAAFFDPEVDCILDIGGQDMKCIKIKNQTVDSVQLNEACSSGCGSFIETF
                     AKSLNYSVQDFAKEALFAKNPIDLGTRCTVFMNSKVKQAQKEGASVADISAGLAYSVIK
                     NALFKVIKLSDASQLGKNIVVQGGTFYNDAVLRSFEKIAGVECVRPDIAGIMGAFGAAL
                     IARERHEAGYQTSMLSIEQINALTFDTKLARCQGCTNHCLLTINRFSGNRQYITGNRCE
                     RGLGKEKNKDNIPNLYEYKNKRLFDYTPLSAEEAARGTVGIPRVLNMYENYPFWATFFK
                     KLGFSVVLSPQSTRKIYELGIDSIPSESECYPAKLAHGHVTWLIHQNVDFIFYPCIPYE
                     RNEFPDSNNHYNCPIVTSYAENIKNNVDEITSGQVKFLNPFMSFASEETLSSQLIKTFG
                     QSEFGIPESEIRDAVAEGWKELAVCRMEMQKKGEEVLQYLKETGRRGIVLAGRPYHVDP
                     EINHGIPELITSYGIAVLTEDSISHLQPVERPLIVMDQWMYHSRLYAAANYVKTRDDLD
                     LIQLNSFGCGLDAVTTDAVNDILTKSGKIYTCLKIDEVNNLGAARIRIRSLISAIRVRE
                     KKQTKRTIVPANYNRVVFTEEMRKNYTILCPQMSPIHFELLEPAFQTAGYNLVVPDVDS
                     RTCVDVGLKYVNNDACYPSLIVVGQLMAAVMSGGYDMSRTAVLISQTGGGCRASNYIGF
                     IRRALEKAGYPDVPVISINLSGLEKNPGFKLTLPLIQHGLYALEFGDIFMRCVYATRPY
                     EAVAGSTDELHEKWKKEVIAFITQKKMLSHGKFKKMCREIIRDFDNLPRKDIKKPRVGV
                     VGEILVKFHPAANNHLVELLESEGAEAVVPDLTDFLLYCFYNTGFKADNLGMSQKSKKI
                     GRLGINFFEWLRSAARDEFTKSRHFTAPAHIDDLARYARDIVSEGNQTGEGWFLTGEML
                     ELIHTGTPNIVCTQPFACLPNHVVGKGVIKELRHRYPGSNIVAIDYDPGASEVNQLNRI
                     KLMLSTANKNLARQTASEQKDQAAG"
     CDS             4712..5569
                     /locus_tag="ctg105_3"
                     /transl_table=11
                     /translation="MNWLNKLERKFGNWAVPNLIVWLIGAYTIGFVLYQVNPSIIGLLM
                     LSPYHILHGQIWRLITWVFMPTDTNLVYLLIMALFYYQLGTTLERTWGTFRFNVYIFGG
                     MLFTVIGAFLLYGIMYLMNGGVTTEMLLIGTSFSTSYINMSIFLAFACMYPDMQVLLMF
                     IIPIKMKWMAAVYGVLIALSFFETGWAGRMAIFMSLLNFIIFFFSTRNLKRYTPHEVHR
                     RQKFKADMRRPQGYAGGAKHKCAVCGRTELDDPTLEFRFCSKCEGNYEYCQDHLFTHQH
                     IRMS"
     CDS             complement(5645..6745)
                     /locus_tag="ctg105_4"
                     /transl_table=11
                     /translation="MAGSTLGTLFKITTWGESHGKGVGVVIDGCPAGLSLCEADIQKFL
                     DRRKPGQSRYATPRKEDDGVEILSGVFEGKTTGTPISLVVFNHNQQSRDYSEIASYYRP
                     GHADYTFDQKYGFRDYRGGGRSSGRETIGRVAAGAVAVKILNELGITFMTYTKSIGPIA
                     VSSGHFDFSEVTKNPLYMPDAEAAENAENYLDACMAELNSSGGIVECIIKGMPAGIGDP
                     VFEKLNANLAKAVMSIGAVKGFEIGDGFGVAKATGKNNNDAFVLGEDGRIAKATNHAGG
                     ILGGMSDGSDIILRAAIKPTPSIAATQRTVNQSGEEISVNIKGRHDPIIVPRAVVVVES
                     MAAITIVDSLFSNMSARMDALKDFYS"
     CDS             6870..8195
                     /locus_tag="ctg105_5"
                     /transl_table=11
                     /translation="MIEKYLVKKITEPVDWKVTVPGSKSMTNRALLMAVLSAGTVRVEG
                     VLFSDDSRHFLACLVSLGFAVQIEEEKKCVTVTGCGGRIPSREAVIDVGSAGTAARFLA
                     AMLGFSDGCYEIRCSAQMKRRPMAELFELLSGAGAKITFLEEEGHLPVRIAGCRSARAD
                     ETAGETPRRLSLDITKSTQFLSALLLIAPMVPEGMKIHITSEKTDGSYIRITRKMMQEF
                     GVSVTFDGRDYEVPAEASYRKETYTVEPDMSAACYFYAAAAVTGGRALVRHVHMDNTQG
                     DLRFLEVLERMGCNADDTPEGVRVTGPADGALRGITVNMNDFSDQALTLAAIAPFADAP
                     VRIEGIGHIRGQECDRIHAIQTNLTALGIRCEEEETAATIYPGSPHGGSVETYDDHRVA
                     MAFSLVGLRTDGIVIENPACCRKTFENYFTVLSELTGKKMEA"
     CDS             8242..8514
                     /locus_tag="ctg105_6"
                     /transl_table=11
                     /translation="MYELLKQEGRAKRGVFHTVHGDIQTPVFMNVGTVAAIKGAVSTED
                     LEQIKCQVELSNTYHLHVRTGDKLIKEVGGLHKFMSWNRPILTDSG"
ORIGIN
        1 ggatcatcga agatgcaaac atccggctgg ttagaaatgc cacatttttt gaaccaaatt
       61 tccctctgta tctccatctg aaatcccacg gtgtgatctt ctgataatat tacttatcac
      121 gaaaaggggc tgcacatttg atgcgcagcc cctttctctg tatctgtcag cctgcagcct
      181 gatccttctg ctccgatgca gtctgccgtg ccagattctt gtttgccgtg gagagcatta
      241 gcttgatacg gttgagctgg tttacctcgc tggcacccgg atcgtaatcg atggccacga
      301 tattggaacc cggatagcgg tgacgcagtt ccttgatgac acccttgccg accacatggt
      361 tcggcaggca ggcgaacggc tgcgtgcaga cgatgttcgg tgttccggtg tggatcagct
      421 ctaacatctc accggttaag aaccagccct cgccggtctg gttgccctcg gatacaatgt
      481 ctcttgcata tctggcaaga tcatcaatgt gcgcaggtgc agtaaagtgc ctgctctttg
      541 tgaattcatc tcttgcagcg ctgcgtagcc actcaaagaa attgatgccc agacggccga
      601 tcttcttgga cttctggctc atgccgagat tgtctgcttt aaagcccgta ttgtagaagc
      661 agtagagcag gaaatcggtc agatccggta caacggcctc tgcaccctcg gattcgagaa
      721 gctccaccag atgattgttg gcagccggat ggaacttgac aagaatctcg ccgacaacgc
      781 cgacgcgcgg tttcttgatg tctttgcgcg gaaggttgtc aaaatcgcgg atgatctcgc
      841 ggcacatttt cttgaacttg ccgtgggaga gcatcttttt ctgggtaata aaggcgataa
      901 cctctttttt ccatttctcg tgcaactcgt ccgttgatcc ggcaaccgcc tcgtaagggc
      961 gcgttgcgta gacgcagcgc atgaagatat cgccaaactc cagcgcgtag agtccgtgct
     1021 ggatcagtgg cagtgtcagc ttaaagcccg ggtttttctc cagaccgctc agattgatcg
     1081 agatgaccgg aacgtccgga tagccggctt tttccagtgc acgccggatg aagccaatgt
     1141 aattgctggc gcggcagccg ccgccggtct gggagattaa gaccgcggtg cgcgacatat
     1201 cataaccgcc ggacatcacg gcagccatca gctggccgac cacgatcagg gacggatagc
     1261 aggcatcgtt gttgacgtat ttcagaccga catccacgca ggtgcggctg tccacatccg
     1321 ggacaacaag gttgtacccg gccgtctgga acgccggctc caacagctca aaatggatcg
     1381 gtgacatctg tgggcagagg atggtgtaat tcttgcgcat ttcctccgtg aagacgacgc
     1441 ggttgtaatt cgccggaacg atggtgcgct tcgtctgctt cttctcacgg acacggatcg
     1501 ccgagatcag ggaacggata cggatgcgcg ccgcaccgag gttgttgacc tcatcgatct
     1561 ttaagcaggt gtagatcttg ccggactttg tcagaatatc attgacagcg tctgtcgtga
     1621 cggcgtccag accacagccg aaggaattca gctggatgag gtcgagatcg tctcttgtct
     1681 tgacatagtt cgccgctgcg tacagtctgg agtgatacat ccactgatcc atgacgatga
     1741 gcgggcgctc caccggctgt aagtgggaga tggaatcctc cgtgagcacg gcgatgccgt
     1801 aggaggtaat cagctccgga ataccgtggt tgatctcagg gtctacatgg tacggacgac
     1861 ctgcgaggac gataccgcgt cttccggtct cctttaaata ctgtaagact tcctcgcctt
     1921 ttttctgcat ctccatccgg cagacggcaa gctccttcca gccttcggca accgcgtcgc
     1981 ggatctcaga ttccggaatc ccgaactccg actggccaaa ggtcttaatc agctgggagg
     2041 aaagcgtctc ctcgctggcg aaagacataa acggatttaa gaacttcacc tgaccggaag
     2101 tgatctcgtc cacgttattt ttgatatttt ccgcgtagga ggtaacgatc ggacagttgt
     2161 agtgattgtt ggaatccggg aattcgttgc gctcataagg aatacacggg tagaaaataa
     2221 aatcgacgtt ctggtggatc agccatgtca catgaccgtg tgccagcttt gccgggtagc
     2281 actcggactc gctcgggatg gaatcaattc caagctcgta gatcttgcgc gtcgactgcg
     2341 gggagagtac cacggaaaaa ccgagcttct taaagaaagt tgcccagaac gggtagttct
     2401 cgtacatatt taaaacgcgc ggaataccga ctgtgccgcg tgctgcttcc tcggcggaaa
     2461 gcggggtgta gtcaaacagg cgcttgttct tgtattcgta gaggtttgga atgttgtctt
     2521 tatttttctc cttgccgagg ccgcgctcac agcggttgcc ggtgatatac tggcggttgc
     2581 cggaaaagcg gttgattgtg aggagacagt ggttggtaca tccctgacat cttgccagct
     2641 ttgtgtcgaa ggtcagcgca ttgatctgtt cgatggaaag catggaggtc tggtagcctg
     2701 cctcgtgacg ctctctggcg atcagtgcgg caccgaaagc acccatgatg ccggcaatat
     2761 ccggacggac acattcgaca cccgcgattt tctcaaaact gcgcagtacg gcatcgttgt
     2821 aaaacgtacc gccctgtacg acgatatttt tcccgagctg gcttgcatcg gaaagcttga
     2881 ttaccttaaa taaagcattc ttgatgacag agtacgcaag acccgcagaa atatctgcaa
     2941 cggatgcgcc ctctttctgc gcctgcttta ccttggaatt cataaatacg gtgcagcggg
     3001 ttccaagatc gatcggattt ttggcaaaaa gagcctcctt tgcaaaatcc tgtacagagt
     3061 agttgaggga ttttgcaaac gtctcgatga aagaaccgca gccggaggaa caagcctcat
     3121 tgagctgcac ggaatccacc gtctgattct tgatcttgat acatttcata tcctgaccgc
     3181 cgatgtctaa gatacagtcg acttccgggt cgaagaacgc ggccgcatag aaatgagcca
     3241 ccgtctcaac ctcgccgtca tcgagcatca aagcggcttt taacagcgct tcgccgtatc
     3301 cggtggagca ggagtggacg atctttgcct tcggtggaag gagcgtatag atctccttga
     3361 tggaacggat tgccgttgca agcggacttc cgttgttgtt gctgtagaaa gaatacaaaa
     3421 gggaaccgtc ctcgccgact aaggcaatct tggtcgtggt ggaacctgca tcgatgccca
     3481 gatagcagtt gccctcataa gtggagaaat ctgcggacct gacattgtgt ccgtcgtggc
     3541 gcgcacggaa agcgtcgtac tcttcctggc tggcgaacag aggatccata cgggcaacct
     3601 caaattccat cttgatgccg ttcgcgagcc ggtcgcggag agagacgagc gtggtcgtct
     3661 cacccggctt gtaatttaaa gcggaaccga tcgcagcaaa tagatgggaa ttctccggtg
     3721 tgatggcgtg ttcgtcgtcc agattcaagg tgcggataaa agcagccttg agctcggaaa
     3781 ggaagtgaag cggacctccg agaaaggcaa catgaccgcg gatcggctta ccgcaggcaa
     3841 gaccgctgat cgtctgattg accactgcct ggaaaatgga ggcagagaga tcctctctgg
     3901 tagcaccctc gttgattaac ggctggatat cggtcttggc aaagacaccg caacgcgcag
     3961 cgatcgggta gatggccttg taattcttgg cgtattcatt cagacctgtc gcatccgtct
     4021 ggatgaggga tgccatctgg tcgataaaag aaccggtacc gccggcacag atgccgttca
     4081 tacgctgctc gacattgccg ccctcaaaat agatgatctt ggcatcctca ccaccgagct
     4141 cgatggcaac atcggtctgc ggtgcataat gctgcagggc agtggacacg gcgatcactt
     4201 cctggacaaa cggaacaccg agatgcttgg cgagtgtcag accgccggaa ccggtaatca
     4261 tcggtgcaac agaaaagtcg ccgagtgcat cgtaagcttt ctggagaagg gaggataagg
     4321 tctcctggat attggcaaaa tggcgctcat aatcagagaa gagcagatga tcctcctggt
     4381 ctaaaattgc gaccttgacg gttgtggaac cgatgtcgat tcccaattta tgaagtgtat
     4441 tgttttccat aattccctcc atggctgttt ctcgtaaagt aaatacttta gcagagtaaa
     4501 atatgtaaaa gatttcttct tattataaat agtgtcaatc tggcgataaa cactctacat
     4561 tatacgacag gatatgtcaa aagacaatgt gcattttgcc ggaaaagtat aaactttttg
     4621 taaagaagaa tccctctgat tgacaaagat ttccccgacc gatatactga acaacgtaat
     4681 gtcatttttg gaaaggtcag gaacagagtg tatgaactgg ttaaataaat tagaacgtaa
     4741 attcggcaac tgggcggttc ccaatctgat cgtgtggctg atcggagctt acacgatcgg
     4801 atttgtcctc taccaggtga atccgtcgat cataggactt ttgatgttga gcccgtatca
     4861 catcctgcac ggacagatct ggcgtctgat tacctgggtg tttatgccca cagacacgaa
     4921 tctggtgtat cttctcatta tggcgctttt ctattatcag cttggaacga cactggagcg
     4981 cacatgggga accttccggt ttaacgtcta tattttcgga ggtatgctgt ttaccgtcat
     5041 cggagcgttt ctgctgtacg gtatcatgta tctgatgaac ggcggtgtga cgacggagat
     5101 gcttctcatc ggaacgagtt tcagcacaag ttacatcaac atgtccatct tccttgcgtt
     5161 tgcatgtatg tatccggata tgcaggttct tctgatgttc attatcccga ttaagatgaa
     5221 gtggatggcg gctgtgtacg gcgttctgat tgctttaagc ttttttgaga ccggatgggc
     5281 gggaagaatg gcgattttta tgtcgctcct caactttatt attttcttct tctccaccag
     5341 aaacctcaag cgctatacgc cgcacgaggt gcacaggcgc cagaagttta aggcagacat
     5401 gcgaagaccg cagggatatg cgggcggtgc gaagcacaag tgtgctgtct gcggcaggac
     5461 ggaacttgac gatccgacgc tggaattccg tttctgctcc aagtgcgagg gcaattacga
     5521 atactgtcag gatcatctgt ttacacatca gcatattcgg atgagctaga aagtatgaaa
     5581 aagaaaaagg tgatacttcg attgcgccag ccggcgtaga agaagtatca cctttttgtt
     5641 tcttttagga gtagaaatct tttagcgcat ccatccgtgc gctcatattg gaaaaaagtg
     5701 agtcgacgat cgtgatggct gccatggatt ccaccacgac aacggcgcgc ggaacgatga
     5761 tcggatcgtg gcgtcccttg atgttgaccg agatctcctc cccggactga ttgacagtgc
     5821 gctgtgtggc ggcgatggaa ggggtcggct tgatggcagc ccgaaggatg atgtcgcttc
     5881 cgtcgctcat gccgcctaag ataccgccgg catggttggt tgctttggca atcctgccgt
     5941 cctcaccgag gacaaaggca tcgttgttgt tcttaccggt cgcttttgct acgccaaatc
     6001 cgtccccgat ctcaaaacct ttgacggcac cgatggacat gaccgccttg gcaaggttcg
     6061 cattaagctt ctcgaagacc ggatctccga tgccggcggg catccccttt atgatacact
     6121 ccacaatgcc gccggaggaa ttcagttccg ccatgcaggc atccagatag ttttcggcgt
     6181 tctcggctgc ctcggcgtcc ggcatataga gtggattctt tgtgacctcg gaaaaatcaa
     6241 agtgcccgga agatacggcg atcgggccga tggactttgt gtaggtcata aaggtaatgc
     6301 cgagctcgtt tagaatcttg acggcgacgg cgcctgcggc gacgcgtccg atggtttccc
     6361 gcccggagga gcgtccgccc ccacggtagt cgcggaagcc gtatttctgg tcgaatgtgt
     6421 aatcggcgtg accgggacgg taataggagg cgatctcgct gtagtctctg gactgctgat
     6481 tgtggttgaa aacgacaagc gagatcgggg tgccggtcgt ctttccttca aacacgccag
     6541 agaggatctc tacgccatcg tcctccttgc gcggggtcgc atatctggac tgaccgggct
     6601 tgcgccggtc gagaaacttc tggatatccg cttcacagag agaaagtccc gccggacacc
     6661 cgtcgatgac gacgccgaca ccctttccgt gagattcccc ccaggttgtg attttaaaaa
     6721 gagttcccaa tgtagaccct gccatgtgat tccctcctgc ttacataatg atctttctcg
     6781 attataaaag atttgacttt gcgccgcaac agaaatatgt tatgatttga cggagcagaa
     6841 gtaccagcag gcgaggagaa gaatatttca tgatagagaa ataccttgtg aaaaagataa
     6901 cagagccggt ggactggaag gtaaccgtgc cgggatcgaa gagcatgacg aaccgcgcgc
     6961 ttcttatggc agtgctgtcc gcagggacgg tgcgcgtgga aggcgtcctg ttttccgatg
     7021 attccagaca ctttctggcg tgtcttgtgt cgctcggatt tgcagtgcag atagaggaag
     7081 aaaaaaagtg cgtgaccgtg acgggctgcg gcggcaggat tcccagcagg gaagcggtaa
     7141 ttgacgtcgg aagcgccggg acagcggcgc gtttccttgc ggcgatgctc ggattttcag
     7201 acgggtgtta tgagatccgc tgttcagcgc agatgaagcg gcggccgatg gcggagctgt
     7261 tcgagctgct ttccggtgcg ggggcgaaga ttaccttcct cgaggaggaa gggcatcttc
     7321 cggtgcgcat cgcagggtgc agatctgccc gggcagatga gacggcaggg gagacgccgc
     7381 ggaggctctc ccttgacatt acgaagagca cgcagttttt aagcgcgctg ctgctgattg
     7441 cgccgatggt tccggagggg atgaagatcc acatcaccag cgagaagacg gacggatcgt
     7501 acatccgtat cacacggaaa atgatgcagg aattcggagt gagtgtcact tttgacggaa
     7561 gagactacga ggtgcccgcg gaggcttcct accggaagga gacttatacg gtggaaccgg
     7621 atatgtcggc agcctgctat ttttacgcgg ctgcggcggt gaccggcgga cgggcgcttg
     7681 tgcgtcatgt gcatatggac aacacacagg gagatctgcg ttttctggaa gtgttggagc
     7741 gcatgggatg taatgcggat gatacgccgg agggcgtccg ggtaacggga ccggcggacg
     7801 gtgcgctgcg gggcatcaca gtcaatatga acgatttttc cgatcaggcg ctgaccctgg
     7861 cggcgatcgc gccgtttgcc gacgcgccgg tgcgcataga gggaatcgga catatccgtg
     7921 ggcaggaatg cgaccggatt cacgcgatac agacgaacct gacagcgctt ggcatccggt
     7981 gtgaggagga agagacggct gccacgatct atcccggcag cccccacggc ggaagcgtgg
     8041 agacatacga cgatcaccgc gtggcgatgg cattttccct ggtcggactt agaaccgacg
     8101 ggattgtcat tgagaacccg gcgtgctgcc gcaagacgtt tgaaaattat tttaccgtgt
     8161 taagcgaact gaccgggaag aagatggagg cgtgaagcag cgccggtgtt gcatgagtaa
     8221 taaaaaggag acgaaaaaca gatgtatgaa ttattaaaac aggaaggacg cgcgaagaga
     8281 ggcgttttcc atacggtgca cggagatatc cagacaccgg tatttatgaa tgtgggtacg
     8341 gtggctgcca tcaagggagc tgtctccacg gaagatttag agcagatcaa atgtcaggtg
     8401 gagctgtcaa acacctacca tctgcatgtg cgcaccggag acaagctgat caaggaagtg
     8461 ggaggactgc acaagtttat gtcgtggaat cgtccgattc ttacggattc cggcgg
//
