LOCUS       c00044_gnlPro..        16792 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JNLOKCNI_44.
ACCESSION   c00044_gnlPro..
VERSION     c00044_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 22:55:50
            Original ID  :: gnl|Prokka|JNLOKCNI_44
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16792
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16792
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3255:6792](-)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      complement(3256..6792)
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..16792
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16792
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             complement(15..1520)
                     /locus_tag="ctg44_1"
                     /transl_table=11
                     /translation="MAGVLVLVLAVFTVTSFGNIFLQGKYMCGLLSALLVVSIMLNVSY
                     QYSYEKDYLSEFAAEEESLDKLESNTDKAVLAAGDSGVYRYDQYGALPYDNTSMYMGTN
                     STAYYFSLANSSISDFFSEMYLNTPWEQHYENLDGRTILDRLASVKYFVISGDNFRYLS
                     YGYNKEKGSAGKGKSECRAYENENALPLGYTYDSYIPESEYEKMDVVKKQQALMDGVVL
                     EESTLPEASVDADNENIQYRMEAGDGCALSKGAIRVTKEGAQLKLVFHGLTDSENYLIA
                     DNLDYDSLSPRELIGNSQWKKMSEYDQNKVLDEDSRWRYWKESKEAAMTVSSNDVTKTI
                     KIFTDKYNAYSGRHDFLCNMGYSRSGVRTMTITFANTGVYTYDKLRVVSQPVQGIEEKT
                     VKLGEEALENVKMGTNEITGDISVSEKKALVLSVPYSKGFTAYVDGKETKLQKANTMFM
                     ALELEPGSHEIRLTYCTPYLKAGMLLSVLGLVIYVMLVFRKKK"
     CDS             complement(1624..1848)
                     /locus_tag="ctg44_2"
                     /transl_table=11
                     /translation="VGGCRVFCCCYGGCVCAFFQEEEVPGFEIGIWVVESVLAGAFCRA
                     CAQWFLLCVQQVDLGLWDDDRVYFCEGVS"
     CDS             2253..2705
                     /locus_tag="ctg44_3"
                     /transl_table=11
                     /translation="MLHSRINRPSRKNIDQRSHKRRLLRILMIKTKNTKRNPRQINPQK
                     NQNLIQNLRLIRRHKHRQQSQRIPDHIIMQSCKNIRTIPDIHIPHRQFQLMLYKNRMQN
                     LPQIPPIIRQRIQMLRNPVMTPHQRLSIPRKLIINKPRNNPKNQRI"
     CDS             complement(3256..6792)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg44_4"
                     /sec_met_domain="PFOR_II (E-value: 6.7e-20, bitscore: 61.3,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 1.3e-83, bitscore: 270.1,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 1.8e-30, bitscore: 96.2,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 6.6e-14, bitscore:
                     41.9, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 1.2e-12, bitscore: 38.6,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.8e-06, bitscore: 18.3,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 6.8e-23, bitscore: 70.3,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MARKMKTMDGNHAAAHASYAYSDVAAIYPITPSSVMAEATDEWAT
                     QGRKNIFGQEVQVTEMQSEAGAAGAVHGSLAAGALTTTYTASQGLLLMIPNLYKIAGEQ
                     LPAVFNVSARALASHALSIFGDHSDVMACRQTGCAMLCESSVQEVMDLTPVAHLSAIKG
                     KVPFINFFDGFRTSHEIQKIETWDYEDLKDMADMDAIAAFRNHALNPNHPCQRGSAQNP
                     DIFFQAREACNPYYDALPAVVQEYMDKVNAKIGTDYKLFNYYGAADAEHVIVAMGSVND
                     TIEETIDYLAAAGKKVGVVKVRLYRPFCAQALIDAIPESVKQITVLDRTKEPGALGEPL
                     YLDVVAALKDSKFGGVKVFSGRYGLGSKDTTPAQIVAVYENTAKEKFTIGIVDDVTNLS
                     LETGAPIVTTPEGTTNCKFWGLGADGTVGANKNSIKIIGDNTDMYAQAYFDYDSKKSGG
                     VTMSHLRFGKKPIKSTYLIHKANFVACHNPSYVNKYNMVQELVDGGTFLLNCAWDMEGL
                     EKHLPGQVKAFIANHNIKFYTIDGVKIGIETGMGPTRINTILQSAFFKLTGIIPEDQAI
                     DLMKAAAKATYGRKGDDVVQKNWAAIDAGAKQVVEIQVPESWKNAEDEGLHMTHATEGR
                     QDVIDFVNNIQAKVNAQEGNSLPVSAFKDYVDGTTPSGSAAYEKRGIAVNVPVWNPENC
                     IQCNRCAYVCPHAVIRPVALTAEEAANAPEGMKTLDLTGMKEYKFTMSVSALDCTGCGS
                     CVNVCPGKKGAKALAMENLEASADEQKYFDYTVKLPVKEDVIAKFKEATVKGSQFKQPL
                     LEFSGACAGCGETPYAKLITQLFGDRMYIANATGCSSIWGNSSPSTPYTVNAKGQGPAW
                     SNSLFEDNAEFGYGMLLAQRAIRDGLKAKVEDVVANGTNEDVKAAGQEWLDTFAVGATN
                     GAATDKLVAALEACGCDKAKEILAQKDFLAKKSQWIFGGDGWAYDIGFGGVDHVLASGR
                     DINVMVFDTEVYSNTGGQSSKSTPTGAIAQFAAGGKETKKKDMASIAMSYGYVYVAQIS
                     MGADFNQTVKAIAEAEAYPGPSLIIAYAPCINHGIKKGMAKAQTEEELAVKVGYWHNFR
                     FNPAAEGNKFSLDSKAPSMEDYQAFLDGEVRYNSLKRQNPEKAARLFAKNEAEAKARFE
                     YLQKLIALHSAE"
     CDS             complement(7067..7474)
                     /locus_tag="ctg44_5"
                     /transl_table=11
                     /translation="MFITRECDYAVRVVRALWGESRLSVSDICEKEAITAPFAYKILKK
                     LQKAEIVKGYRGVHGGYSLNRGLDELTLYEVYSAIDPDMFIIECLDPKYNCVRDGQDGL
                     PCLVHRELLSVQDELISLLKRKTIQQIMEEA"
     CDS             7826..9466
                     /locus_tag="ctg44_6"
                     /transl_table=11
                     /translation="MISANNITLRVGKKALFEDVNIKFTEGNCYGLIGANGAGKSTFLK
                     ILSGQLEPTNGDVVITPGQRLSFLQQDHFKYDAYTVLDTVIMGNKRLYEIMKEKDAIYA
                     KADFTDEDGIRASELEGEFAEMNGWEAESDAATLLNGLGIETDLHYSQMADLTGSQKVK
                     VLLAQALFGNPDILLLDEPTNHLDLPAIEWLEEFLINFDNTVIVVSHDRYFLNKVCTHT
                     ADIDYGKIQLYAGNYDFWFESSQLLIKQMKEANKKKEEKIKELQEFISRFSANASKSKQ
                     ATSRKRALEKIQLDDMRPSSRKYPYIDFRPNREIGNEVLMVENLSKTIDGVKVLDNISF
                     TLGHDDKVAFVGANEQAITTLFKILVGEMEPDEGNYKWGVTTSQAYFPKDNTAEFDNDL
                     TITDWLTQYSEIKDATYVRGFLGRMLFPGEDGIKRVRVLSGGEKVRCLLSKMMISGANI
                     LILDEPTNHLDMESITALNNGLIKFPGVILFTSHDHQFVQTTANRIMEILPNGTMIDKI
                     TTYDEYLASDEMAKKRHVFEINEEDASDN"
     CDS             complement(9509..10027)
                     /locus_tag="ctg44_7"
                     /transl_table=11
                     /translation="MPEDRKDRREKMAKEAKTNAMRMLDRQKVKYEAFSYECDEFIDGI
                     HSADKIGAPYDQSFKTLVMEGKSGGYFVFVVPIEKEVDRKAAAKAVGEKTVDMIHVKDI
                     TKITGYVRGGCSPLGMKKPYPVVFDASAGEFEEIYVSGGRIGLTLKVPLADLLKVTGGK
                     LADIIMKTE"
     CDS             complement(9978..10754)
                     /locus_tag="ctg44_8"
                     /transl_table=11
                     /translation="MVNMTDIFGNALSIAGSFMDSDLVNRFMMVIFAVILVFGVLNCIL
                     GYRLLRFWMMLGGFLVGGGLALVVVHTMGIQEKSTMLIAALATGVVFAVIAFLIYKAGV
                     FILAAGIGWAASIYFLHPTSSAVFFACILIGVALGSMAVKYCREVLIVATSLIGGIMAG
                     VSLAQLGNLADVPYGLGMSVGFAVLGMLIQFAINKPVSDEEDEETVDEESTEQIYRRNQ
                     DLRQDQSFEQSQDRDMEESIYARGQKGQARKNGKRS"
     CDS             complement(10940..12118)
                     /locus_tag="ctg44_9"
                     /transl_table=11
                     /translation="MSKKRFSGLRLILMVPVVVLVAGGLLIGGRALQEPGEVRTLKKQE
                     VAQTDEGHQEYYFGLLNENEQRGYREILEGIRSFEDKFYLSLSGDNEIDRVYHAVLKDH
                     PELFWVHNREKVYKTTYSGRDYCQFSPGYTYTEEQRQEITQAMENAYQEVLSQIPDGAD
                     DYTKVMTVYTYVIDNTEYVISDDDQSIAGAFWKKQAVCAGYAGAVQYLLERLDIPCIYV
                     EGDAANSTQGHAWNIVELNGQYYYVDATNGDQPDFLEGDATLLAEHKTTIYDYLCPFPQ
                     EYEENYTASDEFPVPACTATDMNFYVRNGACFDTYDWSSVYDLCRLRIDSDAAVVRFKF
                     GSQGAYDEAYMDLIDSNHIQDIAKYYMEVHGLSQISYHYGVIDNMKTLYFMF"
     CDS             12461..13099
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTAC"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg44_10"
                     /sec_met_domain="PTAC (E-value: 1.4e-28, bitscore: 88.9,
                     seeds: 361, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSIKIPIETSARHLHISQEDFEKLFGEGSKPHFIKELSQPGQYLC
                     RERVTVKGPKGTFENMALLGPFRSDTQVEMSLTDTRKLGIPSVIRQSGDIEGTPGCILS
                     GPCGDIEIPRGVIVAKRHIHMTPDEALALHIKDNDEVFVLTKSYGRALIYADVVVRVHR
                     NYHLAMHVDTDEANAFNSDTEPYGVIVRFFDSNFNTDKWIEDELSGIRR"
     CDS             complement(13108..13476)
                     /locus_tag="ctg44_11"
                     /transl_table=11
                     /translation="MEQCRILGEYAQYVEKVRENAEIITMSIFEYDKEEEEQKLQATYE
                     KIGEKRGEKQGELKKAKSIAISLAQEGEPVERIARTLGETEKRLKNGWLKRIKISSAVS
                     SIECYCGTFLYSSAILAG"
ORIGIN
        1 caatggaatt tggattactt tttcttcctg aacaccagca ttacatatat aaccagcccc
       61 agaacagaaa gaagcattcc cgctttcaga taaggcgtac aatatgtaag gcgtatctca
      121 tgtgaaccag gttccagttc cagagccata aacatggtat tcgccttctg aagcttcgtt
      181 tctttcccgt ccacataagc cgtaaatccc ttactgtacg gaacagacaa cacaagagct
      241 ttcttttcgg aaacactgat atcccctgta atctcattcg ttcccatttt tacattctcg
      301 agagcttctt cacccagctt cacagttttt tcctcaatcc cctgcaccgg ctgactcaca
      361 acccttaatt tatcataggt ataaacaccc gtattggcaa aggtgatcgt catagtacga
      421 acccctgatc tggaatatcc catattgcag agaaaatcat gccgtccact gtaggcatta
      481 tacttatccg taaaaatctt tatggtcttg gtcacatcat tggagctgac tgtcatagcc
      541 gcttcctttg attccttcca gtatcgccac cggctgtcct catcaagaac cttattttgg
      601 tcatactcag acatcttctt ccactgactg ttaccaatca gttctctcgg tgaaagactg
      661 tcataatcca gattatctgc gatcaggtaa ttctcactgt ccgtaagacc atggaacaca
      721 agcttcagct gcgccccttc cttcgtcacc ctgattgctc ccttagacag agcacaacca
      781 tcccctgcct ccatacgata ctggatattc tcattatcag catcaacaga tgcctcaggc
      841 agtgtactct cctcaagcac cacaccgtcc atcaaagcct gctgcttttt taccacatcc
      901 attttctcat attccgattc aggaatataa ctgtcataag tataacccag aggcagtgca
      961 ttctcattct cataagccct gcactcactt tttccctttc ctgcagagcc cttctcttta
     1021 ttatatccat aggaaagata gcggaaatta tcaccactta tcacaaaata tttcacagaa
     1081 gccagcctgt ccagaatcgt ccttccgtcc aggttctcat aatgctgctc ccatggtgta
     1141 ttcagataca tttcactgaa aaaatcactg atactgctgt ttgcaagact gaaataataa
     1201 gcagtactgt tcgtacccat atacatagaa gtattatcat agggcaatgc cccatactgg
     1261 tcataacgat agacacctga atccccggca gcaagaaccg ccttatccgt attcgactcc
     1321 agcttatcca gcgactcctc ttcggctgca aactccgaca gataatcctt ctcataagaa
     1381 tactgataag aaacattcaa cataatgctc accacaagca aagcactgag aagcccgcac
     1441 atatacttcc cctgcagaaa aatatttcca aaagaagtaa ccgtaaacac agccaatacc
     1501 agaaccagca caccggccat atttctctgc gtccttgcag ccttcgcaaa cagagccagc
     1561 acacaatagg ccacgaccat aacaaaaatc ttctttttct ccccgacagt cagagtaaac
     1621 agctcaggat acgccttcac aaaaatatac gcgatcatca tcccataagc ccagatccac
     1681 ctgttggaca cataagagaa accattgagc acatgccctg caaaaggcac cagcaagaac
     1741 agattcaaca acccaaatcc caatttcaaa tccaggtact tcttcttcct ggaaaaaagc
     1801 acaaacacac ccgccatagc aacagcagaa tacccggcaa ccccccactg gatcatattc
     1861 tccccgatca gatcacccag atacttctca taataaattt tatcatataa aagaggcaca
     1921 taattctcag cctgaaacct gtccgtacca aaaatcgtca tgatcaccgg aagaaaaata
     1981 accgccgcga tcatcaaagc caccgcataa tagccgataa acttcaccag ccatcccaga
     2041 acatccttca cacttctctc actgaaaatt ccaaaatatc ggaaagccgc ataaataaac
     2101 ataaaaatac agatcatata aaagaaatag aaattcgaca tagccgaaac cgcagtcgcc
     2161 cagataaaca gccatggctt ctccctctta taaatcttat caatccccat cagaaccagc
     2221 ggcagataaa tcataggatt ggaaaaatac ggatgcttca tagccgcata aatcgtccat
     2281 cccgcaaaaa tatagatcaa cgttcccata aacgtcgcct gcttcggatt cttatgataa
     2341 aaacaaaaaa cactaaaaga aatccccgcc agataaatcc tcagaaaaat cagaacctca
     2401 tacaaaacct ccgtcttatc cgccggcaca aacacagaca acaaagtcag cggatccccg
     2461 atcacataat aatgcaaagt tgtaagaata tccgaaccat acccgatatt catatcccac
     2521 ataggcaatt ccagcttatg ctctacaaaa atcgtatgca gaacctccct cagataccgc
     2581 ccataatacg ccagagaatt caaatgctgc ggaatcccgt catgactcca caccaaagac
     2641 tttccattcc ccgcaaactg ataataaata aaccccgcaa taaccccaaa aaccagcgta
     2701 tataatatat agaaatccct cttactatcc ttactcgcaa atctcctcat aacaactcct
     2761 atatctatat caatcctcta aaacaccatg atgattataa tcaaatatct cctccttgtc
     2821 aaacacatcc ccatcccttt atatcccaac ttctcctctc cctttgcatg taccctcact
     2881 cctcccttcc gtcagacatt aagtcttagt caacaatcag ccggggaatg acagaacatc
     2941 tgaagcgaat ctcgagggtt catgtaattt cttagtattt ggaaagccgc gttattcaga
     3001 aattgctcac tgtctgagca aagcgagttt gagcaatttc tgaatgccct tagcggcttt
     3061 tcaaatactt agaaattaca tggttccgag actgagcctc agatgttctg tcattccccg
     3121 gcgtccccct gttccaacac ataaaaagag ccgcgataca aaagtaccgc ggcccatata
     3181 tcgtctggac actataaata gctctatcta tttattttat attattgttt atcaatcgtt
     3241 caaaaaccga aaagattatt cagcgctatg aagagcgatc agcttctgca gatattcaaa
     3301 tctagcctta gcctcagcct cattcttagc aaacagtctt gcagccttct caggattctg
     3361 acgtttcaga gagttgtaac gaacctcacc gtcaaggaat gcctgataat cttccatgct
     3421 cggagccttg gaatcaagag agaacttgtt tccttcagct gcaggattga atctgaagtt
     3481 atgccagtat ccaaccttaa ctgctaattc ttcctctgtc tgagcttttg ccataccttt
     3541 cttaatacca tggttgatac atggagcata agcgatgatc agagatggtc ccggataagc
     3601 ctcagcctct gcaatagctt ttacagtctg gttgaagtca gcacccatgg aaatctgagc
     3661 aacgtataca tagccatagc tcatagcgat ggaagccata tctttcttct tagtctcttt
     3721 accgcctgca gcgaactgag cgatagcacc tgtaggtgta gacttggaag actgtccacc
     3781 tgtgttagaa taaacttctg tatcgaatac cataacgttg atgtcacgtc cactagcgag
     3841 aacatggtca acaccaccga atccgatatc gtaagcccat ccgtcaccac cgaagatcca
     3901 ctgggatttc ttagccagga aatctttctg agcaaggatt tcttttgctt tgtcacatcc
     3961 gcaagcttca agagcagcaa caagtttgtc tgtagcagcg ccgtttgtag cacctacagc
     4021 aaatgtatcc agccattcct gaccagctgc cttaacgtct tcgtttgttc cgttagcaac
     4081 aacgtcttca acttttgctt ttaagccatc gcggatagct ctctgagcaa gaagcatacc
     4141 ataaccaaac tcagcgttat cttcgaacag agagttggac catgcaggac cctgtccctt
     4201 agcgtttact gtgtatggtg tagatggtga ggagttaccc cagatagaag aacatcctgt
     4261 tgcgtttgcg atgtacattc tgtcaccgaa cagctgagtg atcagtttag cgtatggtgt
     4321 ttcaccacat cctgcacaag ctccagagaa ctcaagcaga ggctgtttga actggctgcc
     4381 tttaacagtt gcttctttaa atttagcgat aacatcttct ttaaccggca gtttaactgt
     4441 gtagtcaaag tatttctgct cgtctgcgct tgcttcaagg ttttccatag caagtgcttt
     4501 cgcacccttc ttacctgggc aaacgtttac acaagaacca catcctgtac agtcaagtgc
     4561 ggatacggac attgtgaatt tatattcttt catacctgta aggtctaatg tcttcatgcc
     4621 ttcaggagca ttagctgctt cttcagctgt cagagctaca ggacggataa ctgcgtgcgg
     4681 gcagacataa gcacatctgt tacactggat acagttttcc ggattccata caggaacgtt
     4741 aactgcgata ccacgttttt catatgcagc agaaccggat ggtgttgtac catctacata
     4801 atccttgaat gcagatacag gtaaggagtt accttcctga gcattaactt tagcctggat
     4861 attgttaacg aaatcgataa catcctgacg tccttctgtt gcatgagtca tatgaagacc
     4921 ttcgtcctca gcgttcttcc agctttccgg aacctggatc tctacaacct gtttagcacc
     4981 agcgtcgata gctgcccagt tcttctgtac gacatcatca cctttacgtc cgtatgttgc
     5041 cttggcagca gctttcataa ggtcgattgc ctgatcttcc ggaatgattc ctgtcagttt
     5101 gaagaatgca gactgaagaa ttgtgttgat acgtgttggt cccatgccag tttcaatacc
     5161 gatcttaaca ccgtcgattg tgtagaattt gatattgtgg ttagcgatga aagcttttac
     5221 ctgtcctggt aaatgtttct caagaccttc catatcccat gcacagttaa ggaggaatgt
     5281 accaccgtca acaagttcct gaaccatgtt gtatttgttt acgtaggatg gattatgaca
     5341 tgctacgaag tttgctttgt ggatcaggta tgtggatttg atcggtttct taccgaaacg
     5401 taagtgggac attgtaacac caccggactt cttggagtca taatcaaagt aagcctgtgc
     5461 gtacatgtct gtgttgtcac cgatgatctt gatggagttc ttgttggcac ctacagtacc
     5521 atcagctccc agaccccaga atttacagtt tgttgttcct tcaggagttg ttacgatcgg
     5581 agcacctgtc tcaagggaaa ggttagtaac atcatcaacg ataccgattg tgaatttctc
     5641 tttagcagtg ttctcataaa cagctacgat ctgtgcaggt gtagtatctt tggaacctaa
     5701 accataacgt ccggagaata cttttacgcc gccgaatttg ctgtctttta atgctgctac
     5761 aacgtcaagg tacagtggct cgccaagtgc acccggctct ttagttctgt caagaactgt
     5821 gatctgtttt acagattccg gaattgcatc gatgagtgcc tgtgcgcaga atggtctgta
     5881 aagacgaact ttgacaacac cgactttctt tcctgctgct gcaaggtagt cgattgtctc
     5941 ctcgattgta tcgtttacag atcccatagc aacgattacg tgttctgcat cagcagctcc
     6001 gtagtagttg aataatttgt aatctgtacc gatcttagcg ttaactttgt ccatgtattc
     6061 ctgaactact gccggaagag catcgtagta tgggttacat gcttctcttg cctggaagaa
     6121 gatatcaggg ttctgagcag aacctctctg acatgggtga ttcggattaa gagcatggtt
     6181 acggaatgca gcgattgcat ccatatctgc catatccttc agatcttcat aatcccatgt
     6241 ttcaatcttc tggatctcgt gagatgtacg gaatccatcg aagaagttga tgaacggaac
     6301 tttacctttg attgctgaaa ggtgagcaac aggtgttaag tccataactt cctgtacaga
     6361 agattcgcag agcattgcac atccggtctg acgacaggcc ataacgtctg aatgatctcc
     6421 gaaaattgaa agtgcatgag aagcaagtgc acgtgcagat acgttgaata ctgcaggtaa
     6481 ctgctcacca gcgattttgt aaaggttcgg gatcataagt aacagaccct gagatgctgt
     6541 ataagttgtt gttaaagcac ctgctgccag agatccgtgt acagcacctg ctgcaccagc
     6601 ctcagactgc atttcagtta cctgaacttc ctgtccgaaa atgttctttc ttccctgggt
     6661 tgcccattca tctgttgctt ccgccataac agatgaagga gtgatcgggt aaatagcggc
     6721 tacatctgag tatgcatatg aagcatgagc agctgcatgg ttaccatcca tggttttcat
     6781 ctttcttgcc atagtttgtt tttcctcctt aaaggttgat gaaaattaat tatttatttc
     6841 aaggcataag taaaatatac ctcaaatttc attgtagatt ataacataat cttctgcctg
     6901 tgtccaattt gttttgacat attttgtatc ttctgaggta caaagcaggg attttctgtt
     6961 atttcagtag caaatatgtg catttttcga gttgtatatg actaacatta tgcagatatg
     7021 ccaaatttcg gacaaatcag gcagataaaa gtaaaaaaag gaggctctac gcctcctcca
     7081 tgatctgctg tattgttttt ctcttaagga gacttatcag ttcatcctgt acagataaca
     7141 attctctatg taccagacat ggtaatccat cctgtccgtc tctgacacag ttatatttcg
     7201 gatccagaca ttcgatgata aacatatccg gatcaatcgc tgaataaacc tcatataaag
     7261 tcagctcatc cagtcccctg ttcagagaat aaccaccatg tacgcctctg tatcccttca
     7321 cgatctctgc cttctgaagt ttcttcagga tcttataggc aaaaggagct gtgattgctt
     7381 ctttctcaca gatatcggat acgctcagtc tgctctctcc ccaaagcgca cgtaccactc
     7441 gaactgcata atcgcactct cttgtaataa acatagtctt tgcaacctct ctaaaattaa
     7501 ttatccttta ctgtccacat cgctgttttg cataaaacaa tggaaacagt aatcgttatt
     7561 tctgtcatat caatgcctca tatttctgtc tgtcaagagg ctatatttat tctatattat
     7621 aacagtgctt cttttttttg taaataaaag aacccaaaaa agcaaaaaac agttgcaaat
     7681 ttcccaattt acggtacaat gataagcggt tgtaacttat ataataggaa ataatgtaac
     7741 tgtttcctgc gaaagatacg ttttccataa acaatctgcc ggacagttac tgcaaaacaa
     7801 taatttcacg aaaaagaggt atgatatgat ttcagcaaac aatattacat tgcgcgtagg
     7861 taaaaaggcc ctcttcgaag atgtaaatat caaatttact gagggcaact gctacggtct
     7921 catcggtgca aacggtgccg gtaagtccac attccttaag atcctttccg gacagttaga
     7981 gcctaccaac ggtgacgttg ttatcactcc tggccagcgt ctctctttcc tgcagcagga
     8041 tcacttcaaa tatgatgcat atacagttct ggatactgtt atcatgggta acaagagact
     8101 gtatgagatc atgaaagaaa aagatgctat ctatgcaaaa gcggacttca ctgatgaaga
     8161 cggtatccgt gccagcgaac tggaaggtga atttgcagag atgaacggat gggaagcaga
     8221 atctgatgct gctactcttc tgaatggtct tggaattgaa accgatctcc actattccca
     8281 gatggctgac cttacaggaa gccagaaggt caaagttctt ctggcgcagg cactgtttgg
     8341 taatccggac attcttcttc tggatgagcc taccaaccac cttgacctgc ctgctattga
     8401 atggctcgaa gaattcctga tcaactttga caacactgtc atcgttgtat cccatgaccg
     8461 ttacttctta aataaagtat gtactcatac agcagacatc gactacggca agattcagct
     8521 ctatgccgga aactatgact tctggtttga gtccagccag ctcctcatca aacagatgaa
     8581 ggaagccaac aagaagaaag aagaaaagat caaagaactt caagagttta tttcccgatt
     8641 cagtgccaac gcttccaagt ccaaacaggc gacttcccgt aaacgtgccc tggaaaagat
     8701 ccagcttgac gatatgcgtc cgtccagccg taaataccca tacatcgact tccgtccaaa
     8761 ccgcgagatc ggtaacgaag tccttatggt ggagaacctt tccaagacca tcgacggtgt
     8821 aaaagttctg gataacattt ctttcacact cggacatgat gacaaggtag ctttcgtcgg
     8881 tgccaacgaa caggcaatca ctactctgtt caagatctta gttggtgaaa tggaaccgga
     8941 tgaaggaaat tataaatggg gtgttaccac ttcccaggca tatttcccta aggacaacac
     9001 tgcagagttc gataatgacc ttactattac agactggctg acacagtatt ccgagatcaa
     9061 ggatgctact tatgttcgtg gattcctcgg acgtatgctc ttccccggtg aagacggcat
     9121 caaacgtgta cgcgttcttt ccggtggtga gaaagtccgc tgtcttcttt ccaagatgat
     9181 gatctccggt gcaaacattc tcattcttga tgagccaacc aaccacctcg acatggagag
     9241 catcacagca ctgaacaacg gtctgatcaa attcccgggt gttatccttt tcacctcaca
     9301 tgaccatcag ttcgtacaga caacagccaa ccgtatcatg gaaatccttc caaacggaac
     9361 catgatcgac aagatcacta cttacgatga atatctggca agtgatgaga tggctaagaa
     9421 acgtcacgta ttcgagatca acgaagagga cgcttccgat aactaaagaa taaaataaca
     9481 gggtacggct tagccgtacc ctgttatttt attctgtctt catgataata tccgccagct
     9541 ttccgcctgt caccttaagc agatcagcaa ggggaacctt cagtgtcagt ccgatacggc
     9601 cgccactcac ataaatctct tcaaattctc ctgcagatgc atcaaacaca acaggataag
     9661 gtttcttcat tcccagcgga ctgcagccgc ctctcacata tccggtaatc tttgtgatat
     9721 ccttcacatg gatcatgtcc actgtcttct caccgacagc ctttgcagcc gccttacggt
     9781 caacttcctt ttcaatcgga actacaaaaa cgaaataacc gccgctcttt ccttccatta
     9841 ccagagtctt aaaagactgg tcatagggag caccgatctt atccgcactg tggatcccgt
     9901 caataaattc atcacattca taggagaacg cctcatattt aaccttctgt ctgtccagca
     9961 ttctcattgc atttgtctta gcttcttttg ccattttttc tcgcctgtcc tttctgtcct
    10021 ctggcatata ttgattcctc catgtctctg tcctgagact gctcaaaact ctggtcttgt
    10081 ctcaggtcct gatttcgcct gtaaatctgc tcagtgcttt cttcatcaac cgtttcttca
    10141 tcctcttcat cagaaaccgg tttgttgata gcaaactgaa tcagcatacc cagaactgca
    10201 aatcccacac tcattcccag tccataggga acatctgcca gatttccaag ctgtgcaagg
    10261 gaaacccctg ccataatacc accgatcaga cttgtagcca cgatcagcac ttccctgcag
    10321 tatttcaccg ccatggaacc aagagctacg ccgatcagaa tacatgcaaa aaatactgcg
    10381 gagctggtag gatgcaggaa ataaatactg gccgcccagc cgatacctgc tgccaggata
    10441 aacacacctg ccttatagat cagaaatgca atcactgcga acacaactcc tgtcgccagt
    10501 gctgcgatca gcattgttga tttctcctgt attcccattg tatgtacaac caccagcgca
    10561 agaccgccgc ctaccagaaa acctcccagc atcatccaga aacgcagaag cctgtatccc
    10621 agaatacagt tcagcactcc aaacacaaga atcactgcaa atattaccat cataaaacga
    10681 ttcaccagat ctgaatccat aaaactcccg gcaatactca gcgcatttcc aaatatatct
    10741 gtcatattaa ccataatttt cagtcactcc ttttagttat atatttatag cgttccttat
    10801 catcaactga cacatttctc ttagaaccgc cgcacatcct cgcggggcat ttatttcagt
    10861 cggagatcag actgccactg agataagttt atacaactca ctgatagaag cgggggtctt
    10921 ctcaactgaa ccaaacctgt cagaacatga agtataaggt cttcatattg tcgatcacgc
    10981 cgtaatgata ggaaatctgt gacagcccat ggacttccat ataatatttt gcgatatcct
    11041 ggatatgatt actgtcgatc agatccatat atgcctcatc ataagccccc tggctgccaa
    11101 acttaaagcg taccaccgca gcatcactgt caatgcgcag tctgcacaga tcatatacac
    11161 tgctccagtc ataggtatca aaacaggcgc cgtttctcac atagaaattc atgtcagtcg
    11221 ctgtacacgc aggaacagga aactcatcag aggccgtata attctcctcg tactcctgtg
    11281 ggaacggaca cagataatca tagatcgttg tcttatgctc tgccagcagc gtggcatcac
    11341 cctccagaaa gtccggctgg tccccattgg tggcatccac ataataatac tgtccattca
    11401 gctctacaat attccaggca tgtccctggg tactgtttgc agcatcaccc tccacataaa
    11461 tacaggggat atccagacgc tccagcagat actgcacagc tcccgcatag cccgcacata
    11521 ccgcctgttt cttccagaaa gctcctgcta tactctggtc atcatcagag atcacatatt
    11581 ctgtattgtc tatgacataa gtataaacag tcattacctt cgtgtaatca tcagcaccat
    11641 ccggaatctg cgataacacc tcctgatacg cattctccat agcctgcgtg atctcctgtc
    11701 tctgctcctc tgtataagta tatcccggag aaaactgaca gtaatctctg cccgaataag
    11761 tcgtcttata aactttctcc cggttatgta cccagaacag ctccggatga tccttcagca
    11821 ctgcatgata cactctgtct atctcattat ctcctgagag agacagataa aatttatcct
    11881 caaagcttct gatcccctcc aggatctcgc ggtagcctct ctgttcattc tcattaagaa
    11941 ggccgaaata atactcctga tgtccttcat ccgtctgcgc tacctcctgc tttttaagag
    12001 tccttacttc ccccggttcc tgcaaagctc ttccgccgat gagcagtcca ccggccacaa
    12061 gcaccaccac aggcaccata agaatcagac gcagcccgga aaatctcttt ttgctcattc
    12121 aataatcctt cttggttatt attctataag tctgatatta cattactatt tcattctgtt
    12181 ttgtcacatt tagaattgtt attcgttact gttcactccg ctcacagtaa ctgttattct
    12241 aatgtatctt attatagccc agaacacttc tccttgtaaa ccgataaaaa taagttaaca
    12301 ctattttata ataaaaattg tccttcttac aagataaaca ttgcatattt ccaattaaag
    12361 agatacacta aaaagtaagt ataactgctc tgtatcccat cagacaacag gatgtcggac
    12421 agacatatac aattaacata ttgagggagt attgtaataa atgagcatca aaatacctat
    12481 agaaacttct gccagacatc tgcatatctc gcaggaagat tttgaaaaat tattcggaga
    12541 aggaagcaaa ccacatttta tcaaagaatt aagccagccc ggacaatatc tgtgccggga
    12601 acgagtaact gtcaaaggac cgaaaggtac tttcgaaaac atggcacttc tcggtccttt
    12661 ccgcagcgac acgcaggtag aaatgtctct tacagacacc agaaaactgg ggattccaag
    12721 cgtgatacgc cagtccggtg atatcgaagg aactcccggc tgtattttat ccggtccatg
    12781 cggtgatatc gaaatcccca gaggtgtcat cgtagccaaa cgccacatcc acatgactcc
    12841 ggatgaagca cttgccctac atatcaaaga caatgacgaa gtcttcgtcc tgaccaaaag
    12901 ctacggacgc gcacttatct acgcagatgt agtagtcaga gtccacagaa attatcacct
    12961 ggcaatgcac gtagacactg atgaagccaa cgcattcaac agtgatacag aaccttacgg
    13021 cgtgatcgtc aggttctttg acagtaactt caacacagat aagtggatag aagacgaact
    13081 gtcagggata cgcagataaa atccaactta cccggctaaa atagcagacg aatataaaaa
    13141 ggttccacag taacattcaa ttgatgatac tgcggaacta attttaatgc gtttcagcca
    13201 gccattcttt aatcgttttt ccgtttcacc aagggttctt gctattcttt ctacaggttc
    13261 tccttcctgc gcaagcgaaa tggctatgct ttttgccttt tttaattcac cttgcttttc
    13321 acctcgcttt tcgccaatct tttcataagt tgcctgaagt ttctgttctt cttcctcttt
    13381 gtcatactca aatatactca tggtaataat ctccgcattt tcacgtactt tttctacata
    13441 ttgcgcatat tctccaagaa tcctgcactg ctccatcaat ttcctgttgc agtgactttt
    13501 ttgttctttc tttttgtcat agacaatacc tcctgtgtca gcaggagcgt aagaacatac
    13561 tgctcttttc cgaattgttc agaactcctg cttttctaat ttaattggaa ttaaaagcat
    13621 ggatttctga aatgaattta gaatataaga cggcaaaatg ccctgaaact taagaaaaat
    13681 atgctttgat tttatactag catgcttctc tgatggtttc aaggcatttt tgtaaaatta
    13741 tcagatgcta aaagccccgg actggagtag ctgtactgca ccagtctgag gctttcagaa
    13801 tttggggtta taaagttttt atctcaatcc agatcaaaga actgtcgttg acagatgttt
    13861 atctgtgcaa tggattgcgc ttctttttcc gtgccgtagt aaatgtactt gcatgaaatt
    13921 ttcgcataca gggtaacctt tcccttgtaa cctgcacttg tttttaaata actctcatag
    13981 ttttgtagtt cattcaaggt aaagtcatat acgtttccac tgttaacata tacatatcca
    14041 tcttcatatt ctgcctgcct ttcaccagct ttatataccg gaagatgtat ttcttttacc
    14101 tttgtgtttt ctcctccaat tccttcaact tttttaccat catcagactc tatgtacaat
    14161 tgaagtttca ggtcttttgt gtttgttccg gcaaaggaag taccaaccag gttggaatct
    14221 gtcactttca aatggaactc aagtggtttg tttttaataa gctcctggga ttcattgaag
    14281 ttaacattgt caagagtgta ataaacagtc ttttcctgtg cagcatttct gtctgactgc
    14341 tttacaaaca tcaattccgg attaactgcc tgtgcattat atgcggctat gatagtattg
    14401 acaaacaact ttttttccat aagattattg ttattgtttt gtacattgct atgtccgacg
    14461 ccagtataaa ttatattttt atagctgtaa atataatagt tatttcggac atcattgggt
    14521 gaatgatcat aatatccatt tccgtttttc ttgtctttat caccaaggca ataccatact
    14581 acaagatcac ctgaatcatc ctcatctgca ttttcttcca gcgctaattg ataatattgg
    14641 aaatgtgtgg cggcaacggt tattgtttta tcaattttat acggatattc cgttattgca
    14701 ccttcattta cctgagatgc tttagttgta gcttctgtat tttgggtttc tcgcgttgtg
    14761 tttgcaactc ttaattttcc atttgtgaat ccttgcgttt ctgaatatgt tttttcctta
    14821 tttttattca ggaaatatgc catatcactg gaattcttga aaacagtgtt ccaatctgta
    14881 gactgttcat gtgcatctaa ttcttttgcc tgttttaata tattagaagt tgactgcgga
    14941 gcagtgatgc cgtacctatc catgcctgaa gctatgcgaa gtgtctggtt aaaatagtat
    15001 gcccaacctt tccacgtagt atcaccatta atacctccat tctgcgcagt tctatcatac
    15061 acagaggatg acgtattatc atgagccaaa attacactct ttcctgtatt tgcaaattca
    15121 aggattctct gagcaccatt ctctgaaaag tttgtaggat tatttcctcc ataactactt
    15181 ccataaccag caccatcgca aaatccaatg atcaacatgt tatattgatc cagataggtt
    15241 gcatttgcag aatactgggc ttcatattgt cctacagtaa ttgtactaat cttaacatta
    15301 aaatctttta ctttatcaaa cagattttga aacgtagtat ctgtagccaa attccatgta
    15361 caattgacac tattatttgg aataatttgc aatacattaa ttgtattcgc agttgaagtt
    15421 gtatttcgtc tttttgtgta tccgatttca gatgttcgga tttcactgtt attgttgttt
    15481 gtgactacca gtttccacgg cattaatttg atatattcct gcggaatttt tcttgaaact
    15541 gtatacgttg tattaaggga aagttgatat atcccattct ccttttttat aacatttcca
    15601 ttttgcatga ctgcaatatc atccagcttc tcagattttg agaaattacc atcacagttc
    15661 aaatcaatat ataattcgca attatattct gcattagcag gtgaagactg tgcttcgtca
    15721 ataatctgaa actgaaaagt catattttct tcagcaagaa attcattcga tggaccatcc
    15781 cctgttccaa ttgcagaagg agggaaactg ctcaatttaa tctttggctt tggaagttcc
    15841 gcatagaaat ttatatcctc acctgctgta atctctccct ctttgtatac attatcaaat
    15901 ccttttactt cattaaggaa atcataaata taagaagaat tatctaccag agttgtagat
    15961 atcgtttttt tattctcacc ataaatattt cctgcaacta ctaccggata cccgcttttg
    16021 gcaaaattca ccagtttatt ttttatttct ttcgtaatat catttccaga accacgaaca
    16081 gagccaatag tggtacctgt agtcgaatct tcattcccca ccgtagcggc tgtcttttga
    16141 cttccctttg tgacataatc atgattcatc aaaccctgta attcataacg tgccaattta
    16201 tgtccaccaa catgataata aagcactttt ttatctggtc ggaagtttcc ggaataattt
    16261 aaatcctcgg catcatctcc cagatagatc atgtcatatt ttgtatttaa atcatcaata
    16321 tgtccaacaa attcagatgt tgtcatggta gttatttcta ccttggtatt ttcatcatga
    16381 aaaattggga gaaattctct ggcactggca tacttgccta tgttactgtt gattttatca
    16441 tcagcaaatg ttgatttgaa aatcaacttc atcgacttta ctttttgata tgttttgact
    16501 aatttaattt ttttcctatc cctatccaga ttcacagtat cacttattgg catggtatca
    16561 tctctggata ctatcagagt gttattttca tcatataatt ccaatctata tttgtataac
    16621 acccccatat tgcctttacc cgcttcactt tctttaggtc tggctctata aataaatccg
    16681 tcaatatcct ctggatttgc aaacgttatt tgcaaatagt gccgacctgg agtagaatca
    16741 aatttagaat accaaaaatt atcaccacca tttagaacat tttctaccgg at
//
