LOCUS       c00076_gnlPro..        13416 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JNLOKCNI_76.
ACCESSION   c00076_gnlPro..
VERSION     c00076_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 22:55:50
            Original ID  :: gnl|Prokka|JNLOKCNI_76
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13416
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13416
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[4848:13246]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      4849..13246
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..13416
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13416
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             106..594
                     /locus_tag="ctg76_1"
                     /transl_table=11
                     /translation="MPKNKFQEVIFTIIMVFVMVYAMICYNIVLNTGTMTNETFLLAFH
                     ELTFMGPIAFILDFFIIGGLAKKIAFGIVDMRRDNPFHLVLAISAVSVAFMCPCMSFAA
                     TVLIKHAPASQIIPTWLQTTAMNFPMAFFWQIFYAGPFVRFIFGKLFPEKEKAAASAE"
     CDS             948..1946
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SBP_bac_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1044:Bacterial extracellular solute-binding protein
                     (Score: 56.8; E-value: 1.2e-17)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg76_2"
                     /sec_met_domain="SBP_bac_1 (E-value: 2.7e-18, bitscore:
                     56.8, seeds: 129, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRKLFAFGLAVVLALMPVQAFGKTVSVTNVSYDPTREMFEQYNK
                     IFEDHWKEKTGEDVEVIQSHGGSGKQALEVANGLDADVVTLALEYDIESIENAGLIKAG
                     WKDKFDNDSSPYTSTIVFLVKKGNPRDIKDWDDLTKKGVGVVTPNPKTSGGARWNYMAA
                     WAYADKKYGGDEAQMKEFIKKLYRNVVVLDSGARGATTSFVENGQGDVLVAWENEAYLS
                     MRDYPDEYEIVTPSVSILAQPSVAVVDEVVDYRDTRDVATEYLNYLYSDEAQEIAAENY
                     FRPTNEKILKKHSDTFDLNINLANINDYGGWDKVQEKHFTDGGIFDQIYER"
     CDS             2017..2853
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 83.5; E-value: 5.3e-26)"
                     /gene_kind="transport"
                     /locus_tag="ctg76_3"
                     /sec_met_domain="BPD_transp_1 (E-value: 1.2e-26, bitscore:
                     83.5, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKRNKPVIPGFGLSMGITISILSLVVLIPLASLVVYTAKLSFKD
                     FIETITRARVLASFYTSFVCAFAAAVINGIMGTVLAWVLVKYDFPGKRLMDGVIELPFA
                     LPTAVAGIALTSLTSDSGIVGSFFAGFGIKIAYTRIGITVAMIFVGIPFVVRSVQPVLE
                     KMDNSYSEAAGVLGAKKTTIFWKVIFPELKPAIFAGTGLAFGRCLGEYGSVVFIAGNKP
                     YYTEITPLVIMSELQEFDYSSATAIALVMLAVSFFILFLNSMIQQRNARILRGGNV"
     CDS             2853..3677
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 60.2; E-value: 7.1e-19)"
                     /gene_kind="transport"
                     /locus_tag="ctg76_4"
                     /sec_met_domain="BPD_transp_1 (E-value: 1.6e-19, bitscore:
                     60.2, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDNNEKTSEKITKWLLVGISVLFLAVMLLLPLITVITEALRSGWK
                     VYAAAVTDEYTIKALLLTVKATLFAVVFNTVFGVFAAWALTKFQFRGKKLLTTLIDLPV
                     TISPVIAGLIFLLIFGRQSPVYFFLMKLGMKVVFSVPGIIIATVFVTFPFISRELIPVL
                     EAEGSDEEEAAALMGAGGWTIFWKITFPHIKWALLYGVVLCTARAMGEFGAVSVLSGHL
                     RGKTNTLPLHVEILFNEFQYVPAFAVSSLLVIMAVIILVVRSLIEYKGKKEA"
     CDS             3679..4737
                     /locus_tag="ctg76_5"
                     /transl_table=11
                     /translation="MYVELKNINKTYGSYQASRNVNFGIEKGKLIGLLGPSGSGKTTIL
                     RMIAGLETPDSGEVIIDGKVVNDVPASQRGIGFVFQNYALFRYMTVYDNVAFGLKVQKA
                     DKKKIDARVRELIKLVGLEGLEKRYPSQLSGGQRQRVAFARALAPNPQVLLLDEPFAAI
                     DAKIRQELRSWLKEMIGKLGITSIFVTHDQDEAIEVADEIIITNAGRIEQKGTPIGVYR
                     NPETAFTASFFGQPSVLKNADDFHTFAQAEGADKIIVRPEFVKISKLDEVEKFKTSVSQ
                     GVVERVSFRGDNLELQVRVNNSVVTARRSLEKADIRDGETVNVFLYRIFALRGDSVQLI
                     ENEAVRDDFVII"
     CDS             4849..6594
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 71.4; E-value:
                     2.7e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg76_6"
                     /sec_met_domain="FAD_binding_2 (E-value: 6e-23, bitscore:
                     71.4, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1.3e-08,
                     bitscore: 24.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTERIRTDVLIIGGGTAGCFAAYVIGKKSGRKVLIAEKANIKRS
                     GCLAAGVNALNAYITEGRVPQDYVDYAKKDAHGIVREDLLLTMSERLNHVTKVMEDLGL
                     VILKDENGKYVARGNRNIKINGENMKPILAKAAAEQENVTVLNHVNITDYKTENKKVTG
                     AVGFSVNEDIFYDIDAKAVLCATGGAAGLYRPNNPGFSRHKMWYPPFNTGAGYAMGLLS
                     GAEMTTFEMRFIALRCKDTIAPTGTIAQGVGARQVNAHGDIYETKYGLTTSQRVYGTVM
                     ENREGNGPCYLRTEGISKEQEQDLYKAYLNMAPSQTLKWMEAGKGPSEENVEIEGTEPY
                     IVGGHTASGYWVDNNRATTIEGLYAAGDVAGGCPQKYVTGALAEGEIAAEAILEYLNGK
                     DDDRIAAENKEEALERGGEQELSQTAIAKKAEYESHLNASRSLMNAEQLEEAMQKIMDQ
                     YAGGIGTDYRYSGMSLAKADEKIAALLPVVDTLAATDTYELMQIYELRERLIVCQAVIA
                     HLAARKETRWHSFGENTDYPQQSEEWMKYVNSRMENGEIKILYRDLITKENTGLNTAEK
                     GAGER"
     CDS             6591..6905
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_9"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg76_7"
                     /sec_met_domain="Fer4_9 (E-value: 1.8e-13, bitscore: 40.4,
                     seeds: 61, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 2.7e-09, bitscore: 26.9,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.7e-05, bitscore: 14.6,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSIRIQKSKCAGCGRCIEACPGNLIKKDKENKAFIRQVRDCWGCT
                     SCIKECRHDAIRFFLGADVGGRGASMVVSEKPDISTWTVEKPDGTKITIQVNKKDANKY
                     "
     CDS             6936..8054
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PAPS_reduct"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg76_8"
                     /sec_met_domain="PAPS_reduct (E-value: 4.2e-65, bitscore:
                     208.9, seeds: 27, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VCLKNALRKMCVTIYGRFCSDEGVVAGYDNRIRTKYTAKWGVQIA
                     GMIFQTRSSVFAQVRKDSEYKQTEEDNAMSNLSHLDALEAEAIYIMREVAAECEKPVML
                     YSIGKDSSVMLHLAMKAFYPEKPPFPFLHIDTTWKFHEMIEFRDRIAKENGIDMLVYTN
                     EEGVKAGINPFDNGSAYTDIMKTQALKQALTKYGFTAAFGGGRRDEEKSRAKERIFSFR
                     NSAQAWDPKNQRPEMWKLYNTKIQKGESMRVFPISNWTEKDIWQYIQRENIEIVPLYFA
                     KERPVIYRDGNIIMVDDDRLKLRPGEKIENKKVRFRTLGCYPLTGGIESEADTLDEIID
                     ETLSAVSSERTSRVIDHEAAGSMERRKREGYF"
     CDS             8056..9696
                     /locus_tag="ctg76_9"
                     /transl_table=11
                     /translation="MKGLLKFITCGSVDDGKSTLIGHILYDAKLLYTDQEKALELDSKV
                     GSRGGAIDYSLLLDGLMAEREQGITIDVAYRYFTTDNRSFIVADTPGHEEYTRNMAVGA
                     SFADLAVILVDASQGVLVQTRRHARICALMGIRYFVFAVNKMDLIEYDEKRFRDIENQI
                     AALIEELKLANVTIIPVSATEGDNVTTKSDNMLWYKGEALLSHLETVDIKEDTEKGFYM
                     PVQRVCRPNHEFRGFQGQIENGAIRAGDLVTTLPSKEEAHVKSILVGDKEVQEAVQGQP
                     VTIQLDREVDVSRGCVLTIDSGAVLTDSVEADILWMDDNALTDGKNFFVKIGTKMIPGL
                     VTKINYSVDVNTGEKKSAYTLKKNEIASCTLEFSEKIVVDEFDRHRTLGELILIDRVTN
                     MTSACGVVRKTFVSQDRSQIGKVDEQVRAGLKGQTPVVVEFPIGKEEITLDFVEQVEKG
                     LTVLGKHTYLYHPAASENYAETVRHLKAAGLIVLLVLDENTAKDETLKTLDGFYANWQI
                     DGITVKDAIDFVKKKSAFTVQSVHDGNYI"
     CDS             10366..10620
                     /locus_tag="ctg76_10"
                     /transl_table=11
                     /translation="MRLEKVQEALKTKKIHYEYTEENGCGSIDFMFRGLRFHIWEYEDR
                     VWGAETNVFEAGRSQDIEGDYEEIISGEILSWPDMLPGM"
     CDS             10593..10721
                     /locus_tag="ctg76_11"
                     /transl_table=11
                     /translation="MAGYAAWDVSMLLFTATHSRELRYVKSNVSITAEGNDIYEKI"
     CDS             10699..11463
                     /locus_tag="ctg76_12"
                     /transl_table=11
                     /translation="MIFTKKYRTGQIVLTACIAAVCMFSDVHGAEVAGPPAPKSKSALT
                     QKPEATPIPASTPTPEQETETDKQNPADQGTLSKPDHPDTISADKLVFIGDSRTEGLRD
                     AVNDDSIWSCLSSMGYDWMVSTGVPQVEDQIEDNTAVIILMGVNDLYHVNDYISYINSK
                     AAEWGNRGAQTYFVSVGPVQNDPYCSNAEIESFNAAMQASLSGVTYIDVYSHLVSEGFS
                     TVDGTHYPDSVSVDIYNYILDHLEEQMSGIWG"
     CDS             11729..13246
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg76_13"
                     /sec_met_domain="Fer4_7 (E-value: 1.2e-11, bitscore: 35.0,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 1.5e-11, bitscore: 33.8,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 5.9e-06, bitscore: 16.7,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRGLYSSKTEIRHKIFTEIARMAYEGQSPEMLEELPYKIVPGEIA
                     TYRDSIFLERAVVGERLRVAMGMSLRKVTEHAPISKGVEASVIEEKYYEPPLINVIKFA
                     CNSCPEKRVMITEGCQGCLEHPCVEVCPKKAVHMEGGRSHIDEDACIKCGKCLEACPYN
                     AIIKQERPCSKACGMNAIGSDEYGRAEIDQDKCVSCGQCLVSCPFSAIVDKGQIFQTIM
                     ALKSETPVYAIVAPAIAGQFPGMENNKIRGAFQALGFTDVREVAVGADLCTVEEAKDFL
                     EEVPEKLPFMATSCCPSWSMMAKKLFPEQAKCISMALTPMVLTARLIKQKEPDCKIVFV
                     GPCAAKKLEASRKSIRSYVDFVLTFEEVAGMFDAKGVDWKDIPEGEPLFHASADGRGFA
                     VSGGVAEAVVHAVKRIDPDREVKVMNAEGLQNCKKMLQMAKIGKYNGYLLEGMACPGGC
                     VAGAGTIQTVKKAAAALEKMKKEASFTDAYDSKYRARLESLEKFDVE"
     CDS             13185..13310
                     /locus_tag="ctg76_14"
                     /transl_table=11
                     /translation="MPMTPNTEQDWKVWRNLMWSEILTESVKSYMDCKCLNAISI"
ORIGIN
        1 gaaacagata tttggtatta ttggaaacgg tacatcctcc tggatggtta tgaacaacac
       61 aaatctctaa ttgatgttat tcatactatc taaggaggat tttttatgcc taaaaacaag
      121 tttcaggaag ttatttttac gattatcatg gtgtttgtaa tggtttatgc catgatctgc
      181 tacaacattg tactgaatac agggacaatg acaaatgaga catttctgtt agcttttcat
      241 gaattaacat tcatgggacc gattgcattt attcttgatt tctttatcat cggtggtctt
      301 gcaaagaaga ttgcatttgg tattgtggat atgagaagag ataatccgtt tcaccttgta
      361 cttgcaatct cagcagtatc cgttgcattt atgtgtccat gtatgagctt tgcggcaact
      421 gtgctgatca aacatgcacc ggcaagtcag atcattccca catggctcca gacaacagca
      481 atgaactttc cgatggcatt cttctggcag atcttttatg ccggaccatt cgtaagattt
      541 attttcggaa agcttttccc agagaaagaa aaggcagcag cttctgccga ataaaaaata
      601 tgtaattttg actgcagcat tctgtatttc aggatgctgc tttttttgtg ttcttatcta
      661 cacgttactg ttcactccgt tctcagtaac gtagccaaaa ttcattccag attgcctgcg
      721 gcaatggaat tttggcttgt atgtctcggg attttggcac attcatgcca aaacacctcg
      781 cgggatagtg atgtgtgaac agtaacatct acacaacgta aattgtactt attttaatac
      841 actattgaca aattctgtca tttcttgtaa tatcatataa aacatatcga ataactatga
      901 aaagtagaga atgcaaaaaa ctactggtac tttaaaggag atgaaacatg atcagaaaat
      961 tatttgcctt tggtcttgca gttgtactgg cactgatgcc ggtacaggct tttggaaaaa
     1021 cggtgtctgt caccaatgtt tcctatgatc ctaccagaga gatgtttgaa cagtataata
     1081 aaatatttga agaccactgg aaggagaaga cgggggaaga tgtggaagtg atacagtccc
     1141 atggcggttc agggaaacag gcacttgagg ttgccaatgg tctggatgca gatgtggtaa
     1201 ccctggcact ggaatatgat attgagtcta ttgaaaacgc agggctgatc aaggcaggat
     1261 ggaaagataa atttgacaat gacagttctc cttatacatc cactatcgta tttctggtga
     1321 agaaaggaaa tcccagggat atcaaagact gggacgatct gacgaaaaaa ggagtgggag
     1381 tagtaacacc aaatccgaaa acctccggcg gtgccagatg gaactacatg gcagcgtggg
     1441 cttacgcaga taaaaagtat ggtggcgatg aagcgcagat gaaggaattt attaagaaac
     1501 tttaccggaa tgtggtggtt cttgactcag gcgcaagagg tgcaacgacc tctttcgtgg
     1561 agaacggaca aggagatgtg ctggttgcgt gggaaaatga agcttatcta tccatgcggg
     1621 attatccgga tgagtatgag attgttactc caagcgtaag tattttggca cagccttctg
     1681 tggcagtggt agatgaagtg gtggattaca gagatacaag agatgtggca actgagtatt
     1741 tgaattatct gtattccgac gaagcacagg agatcgcagc agagaattat ttccgcccca
     1801 ctaatgagaa aatcctgaag aagcacagtg atacgtttga tctgaatata aatctggcaa
     1861 atatcaatga ttatggcgga tgggataaag tgcaggagaa acatttcaca gatggcggaa
     1921 tttttgatca gatttatgag agataaagga agacaagatg aagcaagagc ataagcacag
     1981 acagaatata tgagacagga gaggtggtaa ttgattatga aaaaaagaaa taaaccggtg
     2041 attccagggt ttgggctctc catgggaatt accatttcca tattgagtct ggtagttctg
     2101 atccccctgg caagcctggt ggtctacaca gcgaagctga gttttaaaga ttttatcgaa
     2161 accatcacaa gggccagagt gctggcatcc ttttatacca gttttgtatg tgcttttgca
     2221 gcagcagtaa taaatggaat tatgggaact gttcttgcgt gggtgcttgt gaaatatgat
     2281 tttccgggca agagacttat ggatggggtg atcgaacttc cctttgctct tcccacagcg
     2341 gtagcaggta ttgcactgac atccctgacc tcagattcgg gaattgtcgg cagctttttt
     2401 gcaggattcg gtatcaagat cgcatacaca agaataggta ttacagtggc tatgatattt
     2461 gtaggaatac cgttcgttgt gcgaagtgta cagccggttc tggaaaagat ggataattct
     2521 tacagcgagg cagcaggagt gctgggagca aagaaaacaa ctatcttctg gaaggtcatt
     2581 tttccggaac tgaagcccgc gatctttgcg ggaaccggac ttgcgttcgg aagatgtctg
     2641 ggtgaatatg gaagtgttgt atttatcgca ggaaataaac cctattatac agaaatcaca
     2701 ccgctggtta ttatgtcaga gcttcaggaa tttgattatt caagtgcaac ggcaatcgca
     2761 cttgtgatgt tggcagtttc attttttatt ctgttcctta acagtatgat acagcagaga
     2821 aatgcaagaa ttttaagagg aggaaatgtc tgatggacaa caatgaaaag acttcggaga
     2881 aaattacaaa atggctgctt gtcgggatca gtgttttgtt tctggcagtc atgctccttc
     2941 ttcctctgat cactgtgatc acagaagcat tgcggagcgg atggaaggtc tatgcagctg
     3001 cagtgacaga tgagtacacc atcaaagcac ttcttcttac agtgaaggca acactctttg
     3061 cagttgtttt taacactgtt tttggtgttt ttgcagcctg ggcactgacg aagtttcagt
     3121 tcaggggtaa aaagcttctc actaccctga tcgatcttcc ggttactatt tcccctgtta
     3181 ttgcaggttt gatctttctt ctgattttcg gacgacagag tcctgtttac ttttttctca
     3241 tgaagttagg gatgaaagtt gtattctctg taccgggaat cattattgca actgtatttg
     3301 taacctttcc ttttatttcc agagaactga ttccggttct ggaagcagaa ggaagcgatg
     3361 aggaggaagc ggcagccctg atgggagcag gtggatggac cattttctgg aagatcacat
     3421 tccctcatat caaatgggca ttactgtatg gagttgtgct ctgtacggca agagcaatgg
     3481 gagagtttgg agcggtatct gtactttccg gacatttaag aggaaagacc aatacacttc
     3541 ctcttcatgt agagattttg tttaatgagt ttcagtatgt tccggcgttt gccgtatctt
     3601 cgctgcttgt gatcatggca gttatcattc tggtagtcag aagcctgatt gaatataaag
     3661 gaaagaagga agcctgatat gtatgtagag ttaaaaaata tcaataagac atatggttct
     3721 taccaggcat caaggaatgt gaatttcgga attgagaaag gtaaactgat tggtctgttg
     3781 ggaccaagcg gaagcggaaa aacaactatt cttcgaatga tcgcaggtct ggaaaccccg
     3841 gacagcggag aggtcattat tgatggaaaa gtggtaaatg atgttccggc cagtcagcgt
     3901 gggattggat ttgtatttca gaattatgcg ttgtttcgct atatgacagt ttatgacaac
     3961 gttgcatttg gtttgaaggt tcagaaggct gataagaaga aaattgatgc cagagtcaga
     4021 gagctgatca aactggtggg gctggaagga ctggaaaaaa gatatccaag ccagttatcc
     4081 ggcggccaga ggcaaagggt ggcatttgcc agagcccttg ctccaaatcc ccaggtgctg
     4141 cttctggatg agccctttgc agccattgat gcaaaaatcc gtcaggaact gcgaagctgg
     4201 ttaaaagaga tgatcgggaa gctgggaatt accagtattt tcgttactca tgatcaggat
     4261 gaggccattg aagtagcaga tgagattatt atcactaatg caggacggat cgaacagaaa
     4321 ggaactccca taggggttta cagaaatcct gagacagctt ttacagcgtc cttcttcgga
     4381 cagccatctg tgttgaaaaa tgcggatgat ttccatacct ttgctcaggc agaaggagca
     4441 gacaagatca ttgtccgccc ggaatttgta aaaatctcca aactggatga ggtggagaag
     4501 ttcaaaactt ccgtatccca gggagtggtt gaacgggttt ctttcagggg agataatctg
     4561 gaacttcagg tgagagtcaa caattccgta gtaactgcca gaagaagcct ggagaaagca
     4621 gatatccggg acggtgagac tgtgaatgta ttcctttaca ggatttttgc actgagaggt
     4681 gacagtgtac agctgatcga aaatgaggct gtaagggatg actttgtaat tatctgacaa
     4741 cggtggctgc ggcgactgac gacaatgaag aaataagaaa ttcagaggca agactgatcg
     4801 gaaaatcaac ttgttggcac actggtatgg aggaaaggat aagagagaat gagaacagag
     4861 agaatcagga cagatgtgct gatcatcggc ggcggtacgg caggatgctt tgcagcctat
     4921 gtgatcggca aaaaaagcgg cagaaaagtt ctgatcgcag agaaagcgaa tattaagcga
     4981 agcggatgtc tggcggcggg cgtgaatgca ttgaacgcat atattacaga aggcagagtg
     5041 ccgcaggatt atgtggatta tgccaaaaag gatgcccatg gaatcgtaag agaagacctt
     5101 cttcttacca tgtcagagag actgaatcat gtgacaaagg tgatggaaga tctggggctg
     5161 gtcatcctga aggacgaaaa cggaaaatat gttgccagag gaaaccgaaa catcaagatc
     5221 aatggcgaaa atatgaagcc aatccttgca aaggcggcag ctgaacagga gaatgttacg
     5281 gttctcaatc atgtaaatat tacagattat aaaacagaaa acaaaaaagt cacaggcgca
     5341 gttggattta gcgttaatga ggatattttc tatgacattg atgcgaaagc agttctttgt
     5401 gccacaggtg gtgcagcggg actttacaga ccgaataatc cgggattttc cagacataag
     5461 atgtggtatc ctccgtttaa cacaggtgca ggatatgcaa tgggacttct ttccggtgcg
     5521 gagatgacaa cctttgagat gcgtttcatt gcattgagat gtaaggacac gattgctcct
     5581 acaggaacta ttgctcaggg tgttggggcc agacaagtca atgcacatgg tgatatttat
     5641 gaaacaaaat atggtctgac aacttcccag cgagtttacg gtacagtcat ggagaacaga
     5701 gaaggaaacg gtccatgtta tctcagaacg gaaggtattt ccaaagaaca ggagcaggac
     5761 ctttacaaag cttacctgaa tatggcaccg tcccagactc tgaaatggat ggaagccgga
     5821 aaaggaccat ccgaagagaa tgtagagatt gagggcacag agccatatat tgtaggcgga
     5881 catacagcca gcggttactg ggtagataat aacagagcta caactattga aggtttatat
     5941 gcagccggag acgtagcagg aggatgtccg cagaaatatg taaccggcgc actggcagaa
     6001 ggtgagatcg cagcagaggc gattttggaa tatctgaatg gcaaagatga tgaccggatc
     6061 gcagcagaaa ataaggaaga ggctttagag cgtggcggag aacaggagct gtctcaaact
     6121 gcaatagcta agaaggcaga atacgaatca catttgaatg cttcccgttc tttgatgaat
     6181 gcagagcagc ttgaggaagc catgcagaag atcatggatc agtacgcagg aggaatcggt
     6241 acagactaca gatacagcgg gatgagtctt gcaaaggcag atgaaaagat cgcagcattg
     6301 ttgccagtag ttgacactct ggcagcaaca gatacttatg aactgatgca gatttatgaa
     6361 cttcgcgaac gactgatcgt gtgccaggca gtgatcgcac atctggcagc cagaaaggaa
     6421 accagatggc atagtttcgg agagaataca gactacccgc agcagagcga agagtggatg
     6481 aaatatgtaa actcccgtat ggaaaacggc gagattaaga tcttatatcg tgacctgatc
     6541 acaaaggaaa atacaggttt gaatacagca gagaaaggag caggtgagag atgagcattc
     6601 ggattcagaa aagtaaatgt gcaggatgcg gcagatgtat cgaagcctgt cccggaaatc
     6661 tgatcaaaaa ggataaagag aacaaagcct ttatccgtca ggtaagagac tgctggggat
     6721 gtacttcctg tattaaggaa tgcaggcatg atgccatccg ctttttcctt ggagctgatg
     6781 tggggggcag aggtgcaagt atggtggtat cagagaaacc ggatatttcc acatggacag
     6841 tggagaagcc ggatggcact aagatcacta ttcaggttaa taagaaagac gctaataaat
     6901 attaaacata agtatgtact ctcagagtct ttagagtgtg tttgaaaaat gctttacgca
     6961 agatgtgcgt cacaatttat gggagatttt gttcggatga gggcgtcgta gcgggctacg
     7021 acaaccgaat tcggacaaaa tataccgcaa agtggggcgt gcagattgcg ggaatgattt
     7081 ttcagacacg ctctagtgta tttgctcaag tacgaaaaga ttccgagtat aaacaaacag
     7141 aggaggataa tgcaatgagt aacttatctc atcttgatgc gcttgaggca gaggcgattt
     7201 atattatgcg ggaagtagca gccgagtgtg aaaagccggt tatgctctat tctataggaa
     7261 aggacagctc cgttatgctc catctggcga tgaaggcatt ttacccggag aaaccgcctt
     7321 ttccctttct tcacattgat actacatgga aattccatga gatgatcgaa ttccgcgaca
     7381 gaatcgcaaa ggaaaacgga attgatatgc tggtttacac caatgaagag ggtgtaaagg
     7441 caggaatcaa cccatttgac aatggttctg catatacaga tatcatgaaa acacaggcct
     7501 taaaacaggc tctgaccaaa tatggattta cagcggcatt tggaggcggc cgtcgtgatg
     7561 aggagaaatc cagagcaaaa gaaagaattt tctctttccg taattcagct caggcatggg
     7621 atccgaaaaa ccagagaccg gagatgtgga agctttataa cactaagatc cagaagggag
     7681 agagtatgcg agtattccca atttccaact ggacagaaaa ggatatctgg cagtacattc
     7741 agcgtgaaaa tatcgaaatt gtaccgttat attttgcaaa agaaagaccg gtcatctaca
     7801 gagacggaaa tatcattatg gtggatgatg acagattaaa actccgtccg ggtgaaaaga
     7861 ttgaaaacaa aaaagtcaga ttccgtactc ttggatgcta tccgcttact ggaggtattg
     7921 aatctgaagc agatactctg gatgagatta ttgatgagac gttaagtgct gtttcttctg
     7981 aacgtaccag cagggtgatc gaccacgagg cagcaggcag catggagaga agaaagagag
     8041 aggggtattt ctagaatgaa aggattattg aaatttatta catgcggaag tgtggatgat
     8101 ggaaaatcca ctctgatcgg acatattctt tatgatgcaa agcttctcta tacagatcag
     8161 gagaaagctc tggagctgga ttccaaagta ggaagcagag gcggtgccat tgattattct
     8221 cttcttctgg acggtctgat ggcagagcgt gaacagggaa tcaccattga tgttgcatac
     8281 cgttatttta caacagataa cagaagcttc attgttgcag atacacccgg acatgaagaa
     8341 tatacaagaa acatggcagt gggtgcgtcc tttgcagatc tggcagttat cctggtggat
     8401 gcttcacagg gagtactggt acagacaaga cgtcatgcaa gaatctgcgc attgatggga
     8461 atccgttact ttgtatttgc agtaaacaaa atggatctta ttgaatatga tgaaaaacgt
     8521 ttccgcgaca ttgagaatca gatcgcagca ctgatagaag aactgaaact tgccaatgta
     8581 actattattc cggtatctgc cacagaaggt gataacgtta caaccaaatc tgacaatatg
     8641 ctatggtata aaggtgaggc gcttctttcc catctggaaa ccgtagacat taaggaagat
     8701 acagagaagg gcttctatat gcctgtacag agagtctgca gaccaaatca tgagtttcgc
     8761 ggattccagg gacagattga aaatggtgcc atcagggcag gcgaccttgt gactactctt
     8821 cccagtaaag aagaagctca tgtaaagagt attcttgttg gcgataaaga agttcaggaa
     8881 gctgtacagg gacagcctgt taccatccag cttgacagag aagtagatgt ttcccgcggc
     8941 tgtgtactta ccattgattc cggcgcagtt cttacagact ctgtggaagc agatatcctc
     9001 tggatggatg acaatgctct tacggatggc aaaaacttct ttgtaaaaat cggtacaaag
     9061 atgatccccg gcctggttac aaaaatcaat tattctgtgg atgttaatac aggtgaaaag
     9121 aaaagcgcat ataccttaaa gaaaaatgag attgcttcct gtactctgga attctcggag
     9181 aagatcgttg tagacgaatt tgacaggcac agaacactgg gtgagctgat tctgatagat
     9241 cgtgtcacaa atatgacttc tgcctgcggt gttgtgagaa aaacctttgt ttctcaggat
     9301 agatcccaga tcggaaaagt ggacgagcag gttcgtgcag gactgaaagg tcagacaccg
     9361 gtagtagtgg aattcccgat cggtaaagaa gaaatcactc ttgattttgt agagcaggta
     9421 gaaaagggac tgactgtact tggaaaacat acctatctgt atcatccggc agcgagtgaa
     9481 aactatgcag aaactgtccg ccatcttaag gcagcaggtc tgatcgtact tcttgttctt
     9541 gatgaaaata cagcaaaaga cgagacatta aagactctgg atggtttcta tgcgaactgg
     9601 cagattgacg gaatcactgt gaaagatgcg attgatttcg tgaaaaagaa atctgcattt
     9661 acagtgcaga gtgtacatga tggaaattat atctgattat aacagggcta taaatcgccg
     9721 cagagacaaa gaaagtctct gcggtatttt gttttcttga caagtgttgt tacagcggat
     9781 tatacttatt ttcaaatatt cagaatccat aataatacag acaggaaaga taacagaaat
     9841 atgcaaacga acaatgaaag taaacaaaac caaaaaaaga gatgatgctt ggaactttgt
     9901 ttgtaattgc tacgatcatc atcctggcga taccaacgaa gaaaagacag aaataaagat
     9961 gagtgaatat cgatcagaat gtagaatggg caattggtta ctgttcacac accattatcc
    10021 cgcgaggtgt tttggcatga atatgccaaa atcccgagac atacaagcca aaattccatt
    10081 gccacaggca atctggaatg aattttggct aagttactgt gaacggagtg aacagtaacg
    10141 gcaattgtga agtggcattc agattacata ttatgcagca gagtatgata taattcgttt
    10201 tgtataatgg cgtcaggatt aagagcatat gtagagctgt gtagcgaagc ggattgcgaa
    10261 tatctgtttg acttttgatg ggtgtacacg agaacatttt tttacagtga aagttatctg
    10321 tattatatta cagagggtac tgtacagata atcaggaggt attttatgcg tttggaaaaa
    10381 gtacaggaag cgttaaaaac aaagaaaatt cattatgaat atacagagga aaacggatgc
    10441 ggaagcatcg actttatgtt tcgcggtctg agattccata tatgggaata tgaagatcgt
    10501 gtctggggag cggagacaaa cgtgttcgaa gcaggcagaa gccaggatat tgagggagat
    10561 tacgaggaaa ttatttccgg agaaatcctc tcatggccgg atatgctgcc tgggatgtaa
    10621 gtatgttact gttcacagca acacactcca gggagttgag atatgtgaaa agtaacgtaa
    10681 gtattactgc agaagggaat gatatttacg aaaaaatata gaaccggaca aatcgtatta
    10741 accgcatgta ttgcagctgt ctgtatgttt tcagatgtcc atggggcaga agtggcaggt
    10801 ccgccggcac cgaaatccaa atcggcactg acacaaaaac ctgaagcaac accaatacct
    10861 gcatctactc caacaccgga gcaggaaact gagacagata aacagaatcc ggcagaccag
    10921 ggaactttaa gcaagccaga ccatccggac actatctccg cagataaact ggtatttatc
    10981 ggagattcca gaacagaggg attgagggat gcggtaaacg atgacagcat ttggtcctgt
    11041 ctttcttcta tgggatatga ctggatggta tctacaggag tgccgcaggt agaagatcag
    11101 attgaggaca atacagcggt tattatcctg atgggtgtta atgatcttta tcatgtcaat
    11161 gactacatca gttatattaa ttccaaagct gctgaatggg ggaacagagg agcgcagact
    11221 tatttcgtgt ctgtaggtcc ggtgcagaat gatccctatt gcagtaatgc ggagattgaa
    11281 agttttaacg cggcaatgca ggcaagcctg agtggagtta cctacataga cgtatattcc
    11341 catctggtat ctgagggatt ttccaccgta gacggaaccc actatccgga cagtgtgtcc
    11401 gtagatattt ataattatat cttggaccat ctggaggaac agatgagtgg aatctgggga
    11461 taacaacata tgaacagcaa cttcgggggc gacaattcag cgaaaattct gatgttgtgt
    11521 tgagcctgga agcatttggt gatatgatat gcagataagg aaacggaaat gagcggaatt
    11581 tcgtttctct gtgaagtggc tgaaagttca gcaggaggaa aaatgagtgt gctgattgca
    11641 gcagtgatga aattataaat ggaaattgtt cggtgtccct gcattggatt gccgtacagt
    11701 tatccgaatc gaaaatcagg aggaaaaaat gagaggactg tattcatcca aaacagaaat
    11761 cagacacaaa atttttacag aaattgcgag gatggcatat gaaggccagt ctccggagat
    11821 gctggaagag cttccctaca agatcgtacc cggtgaaatt gcgacttatc gtgacagtat
    11881 ttttctggaa agagcggtag ttggtgagag acttcgcgtt gcaatgggga tgtcactgag
    11941 aaaggttaca gagcatgcgc caatttccaa aggtgtggag gccagcgtta ttgaggaaaa
    12001 gtattatgaa ccgccgctta tcaatgtgat caagtttgcc tgtaattcct gccctgaaaa
    12061 aagggtaatg atcacagagg gctgtcaggg gtgcctggag catccctgtg tggaagtctg
    12121 tccaaagaaa gcagtgcata tggaaggcgg cagatcccat attgatgaag atgcctgtat
    12181 caaatgcgga aagtgtctgg aagcctgtcc gtataatgca atcatcaaac aggaacgtcc
    12241 atgttcaaag gcatgcggta tgaatgctat tggctctgat gaatatggaa gagcagagat
    12301 tgatcaggat aaatgtgtat cctgcggaca atgtctggta agttgtccgt tcagtgctat
    12361 tgtagacaaa ggacagattt tccagactat tatggcatta aaaagtgaaa caccggtgta
    12421 tgcaatcgtg gcgcctgcca ttgcaggcca gtttccgggt atggagaata ataagatacg
    12481 gggagcattt caggcacttg gctttacaga tgtaagagag gttgccgtcg gtgcagatct
    12541 gtgcacagtg gaggaggcaa aggacttttt ggaagaagtt cctgagaaac ttcctttcat
    12601 ggctacatcc tgttgtccgt cctggtctat gatggctaag aaattattcc cggaacaggc
    12661 gaaatgtatc tctatggcac tgacacctat ggttctcact gcaaggctga tcaagcagaa
    12721 ggaaccagat tgtaagatcg ttttcgtagg tccctgtgca gccaagaagc tggaagccag
    12781 ccgtaagagt atccgcagct atgtggattt tgtgctgacc ttcgaggaag tagcaggaat
    12841 gtttgatgcc aaaggcgtgg actggaaaga tattccggaa ggagaaccac tgtttcatgc
    12901 cagtgctgac ggaagaggtt tcgcagtcag cggtggtgtg gcagaagcgg ttgtccatgc
    12961 ggtgaagcgt attgatcctg atcgggaagt aaaggtaatg aatgcagaag gtctgcagaa
    13021 ctgtaagaag atgctccaga tggccaagat tggtaaatat aatggatatc tgctggaagg
    13081 aatggcatgt ccgggcggct gtgtagcagg tgccggtact atccagacag ttaaaaaagc
    13141 agcagcggct ctcgaaaaaa tgaagaaaga ggcttcgttt acagatgcct atgactccaa
    13201 atacagagca agactggaaa gtctggagaa atttgatgtg gagtgagatt ctgactgaat
    13261 cagtgaaatc ttatatggat tgcaagtgtt tgaatgcaat cagtatatag cagactaaaa
    13321 atgaataatc gtcagaagaa ctgtcaggct gagtgataag tttaactgaa tcggataagt
    13381 cccctgcgga ggttgcgaaa agcaataagc agggga
//
