LOCUS       gnlProkkaDOANKGEL_61   14617 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DOANKGEL_61.
ACCESSION   gnlProkkaDOANKGEL_61
VERSION     gnlProkkaDOANKGEL_61
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-18 11:11:58
            Original ID  :: gnl|Prokka|DOANKGEL_61
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14617
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14617
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[3474:4617]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3475..4617
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..14617
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..14617
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             3..239
                     /locus_tag="ctg61_1"
                     /transl_table=11
                     /translation="MALVYSGEAATAMESNADLSYTVPKEGSNLWIDSWFIPADSTHKE
                     NAEKFLDFLCREDVAMLNFDYVCYAKSGRRRCA"
     CDS             520..1416
                     /locus_tag="ctg61_2"
                     /transl_table=11
                     /translation="MNYHDFKQQIISTLSDRLGSDVRITVSDILKNNDTHLDGLTILAP
                     GQNLAPTIYLDYYYGQYERGRSFSDITDDILTAYRENRPKSPVDISFFTDYDKVKSRVT
                     MKLINYERNRELLKRVPYYRFLDLAIVFLCLVESDSSGTATVLIHNEHLTYWGITRDDL
                     YALAMANTPQLLRYDLRSMTEVLRELFADEFADPAGNDLIEPFPIYVLSNQHRLNGSSC
                     ILYQHLLHDFARRIGSDFYILPSSVHEVLLIPADNQISMSTLSSMVRDVNSSQLAREEI
                     LSDHVYYYSLETDQITM"
     CDS             complement(1419..2870)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045:glycosyl transferase group 1 (Score: 68.1;
                     E-value: 1.3e-20)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg61_3"
                     /sec_met_domain="Glycos_transf_1 (E-value: 1.3e-18,
                     bitscore: 57.2, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMKILFAASEAVPFMKTGGLADVTGSLPGYFDKKHFDVRIIMPKY
                     LCMDEKWKAQLRFVCHFYVNLSWRRQYVGIFETVQNGITYYFVDNEFYFAGDKPYHNIY
                     EDVEKFAFFSKAVLEALPYLDFWPDVIHCHDWQTGLVPVFLRTFYGDQRCYSNIRTVFS
                     VHNLKFQGRFSLPAVIDITGLPEQIFSSDKLESYGEANYLKGGVVYADAVTTVSPTYAR
                     EIMTPEGGEGLDGLMRAREGSLYGILNGIDIREYDPQTDAYLANHYNETNHTEGKGLNK
                     LKLQKLLGLPVDKDVFLLGMVSRMTDQKGFDLIAYVMDELMSTERLQLVVAGTGEARYE
                     EMLRYFAEKYPQKIHVTIGYSEELAHRIYGSCDAFLMPSLFEPCGLSQLMSLRYGTVPI
                     VRETGGLKDTVMPYNEYEQTGTGFSFANYNAHEMLGVLRYAMRVYYTQRKCWNGIAERA
                     MREDFSWKKSAETYARLYEDIVGRP"
     CDS             complement(2899..3375)
                     /locus_tag="ctg61_4"
                     /transl_table=11
                     /translation="MEQIYEIEPLLKAGVCIQIHPQGYSMYPFIDPRRDEVVLAGIEDG
                     SALRRGDVVLYRRENGMLVLHRIYKIGQDGLYLLGDHQTAIEGPVRREQVKGKMTGTVR
                     DGRYMDVGNPGYRMLSVVWLWLRPARRAIMVPAARLRRMVRFALFRRNNKRYNK"
     CDS             3475..4617
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg61_5"
                     /sec_met_domain="PF05402 (E-value: 6.2e-10, bitscore: 29.4,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 1.8e-09,
                     bitscore: 27.6, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLNDRYIKATLAGIPYLLPYGQLIAAPAPATRLNDSGSLLWDGI
                     LEGDSREELLALLADRYHTTERERAALAEDVDQYLHSLCRMGILLADTPESRGDDTPPL
                     FYRIGPLVFSYRGPSLLYDRFFSAFSCEEEDFDQEVLILTGKPASIPYGAVLIHTEELT
                     ICDSGSSYCFFFAAPWGIREMHVKKDGSRAVLYRMPDPDDMHIEDLFHALRFAFLILAQ
                     QKELYVLHSASFLYRGRAFLVSGSSGTGKSTHSALWHDLYQTPLLNGDLNLLGIRDNIP
                     YAYGLPWCGTSGICTPKDYPLGGIIFLKQAAIDQVQSLQPDEKVLHILQRMISPAWTKE
                     LLLRNLHFSEALAPLIFSCRLYCTKEPSAAGILKAAIDAL"
     CDS             complement(4614..6380)
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 302; E-value: 1.5e-91)"
                     /gene_kind="transport"
                     /locus_tag="ctg61_6"
                     /transl_table=11
                     /translation="MLEKFRHYRERIKEGMLRDMWRQTLWIYEYARLYWKQMIFYTLLG
                     LAGTLVSLISSLISRDMVDIITGQQAGLLARTFCLYIGFSVGNVLISQISNYFANKISI
                     SVDNAIKADIFEKMLLTDLESIQNYHTGDLLTRWSSDASNISSGVLNWIPNLVIYTVRF
                     VSIFAVVFYHDPMFALLALIGMPVSMLMSKTLLRRMKGNNERSAAMSAKMSGFNQEAFS
                     NIQTIKAFDLIRLYAERLRGLQREYLTMKLEFQKMSMATSILLSIVGLAVSYSCYGFGI
                     YRVWSGAISYGTMTMFLSLSGSLTGTLNQLVSLVPTAVSLTTSAGRLMDILDMPKEDFS
                     DADQVEQFAARNRTDGIGISFSGVSYAYHNGKQVFCGADFLARPKEIVALVGPSGEGKT
                     TMLRLMLGLLHPQEGERTLIGETDGEKIAVDPSARRLFSYVPQGNTMFSGTIAENMRNV
                     RPEASDEEICEVLKAACAWEFVEKLPDGIYSMVGERGGGFSEGQAQRLSIARALLRRSP
                     ILLLDEATSALDVATERRVLRNIMSTTEPSTCIVTTHRPTVLSICQKVYRIREQKCVQM
                     QEEEIRQMMREF"
     CDS             complement(6610..6984)
                     /locus_tag="ctg61_7"
                     /transl_table=11
                     /translation="MTNYESPVILRTEELAEGVYLASGCYTASAYIHQTPQSGSGEYRI
                     QVNGQHSADHTKEAQTLTISFSLPVTYTSSGGSLVSGSGTNTLVINYNYHQNPTDNIGL
                     GDLVVQADAGLAVTSVNITD"
     CDS             complement(7010..7345)
                     /locus_tag="ctg61_8"
                     /transl_table=11
                     /translation="MTNYESPVMIRTEELAEGVYLASGGIKCDSVYMNGVWQAPDYSDW
                     NGTTRGYKQQFGCLGCPANTASGCGLLSHYVDSGYAGSYDVDNGNRKPSWEKKGYGPDD
                     AVTDWNM"
     CDS             complement(7478..7798)
                     /locus_tag="ctg61_9"
                     /transl_table=11
                     /translation="MQNYEKPEVILMTECSEGVYLASGGQTGEDPTAGGCDSRYMKGAW
                     KKPDYSNSNVQMRAYDRKGCEGCAADDGDGCKLQKGDAKVAGNVYQPVWEQQGLTPDTM
                     VW"
     CDS             complement(7946..9367)
                     /locus_tag="ctg61_10"
                     /transl_table=11
                     /translation="MSGRGKKFLALGVAVVLCLAAAAAMGSLFHWKVTCTPAAFAESSR
                     RLSNPDRGFYYIYGYRITDEPVDYATDLRDRTREDDATRLGMMQINLREYRTGAISEEG
                     LSNVRQLFAAMADSDKKWIVRFLYDWNGENEQYEPENLDIILQHMEQVGDVLREYHSCI
                     YTLQGLFIGNWGEMNGTKYTDPDSMRELAARLADVSDASTFLSVRTPAQWRKITGEAAP
                     DGWTENPLAKRLGLFNDGMLGSVSDYGTYSDNTRQDAGDFSAWTREEELSFQDVLCSSV
                     PSGGEVIVDNPYNDLENAIADLKTMHVSYLNEDYDRNVLDKWAGTVVNTDDCYDGMDGW
                     SYVERHLGYRLWIAGAALSHSFWADTVEVNAALKNSGFAPFYRQTKVCVSVTDEAGAVC
                     YTDEWEEKLLKLSGGNEDDRELALTGTIPIRGWESGTYRVYINLSDADSGEQILLANEA
                     DATENGYCLGEVAVR"
     CDS             complement(9364..11853)
                     /locus_tag="ctg61_11"
                     /transl_table=11
                     /translation="MDTWYWALEYVRVFFAYVMILFVWPSVVFRDYLRGRSRTVRFAFC
                     VTVPVVLLNTVVLSLGVFHILYGWLIAVLFYGTLLLGLLRWHPVRREQIKKISRLFLGT
                     YGIRLLLLRLRNRVKDGIGHVHAQFRQSIRGRRCVYLMLGVVVCFGMVYFSYGAFHDYS
                     YGFGDMYRHHSWIYGLLNGTPFYEGIYPEAMHCFIYAMRVLFGVKIYSSQLFLAGIHVA
                     VFLVSAYLLLKELFAWDGTAVLALALFLTVDLLCIDEIFSMSRLQWTLPQEFGLYTQFL
                     CALFLLRCLKTDFSDRSGSRRERIRKFLTEENLLLFLLSLAASLAIHFYVTMMAFFLCV
                     VIAACRLPSLFQKRRFVSLVKAVCLGVLIAVLPMGIAYAKGVPFQGSIGWAVNVINGTD
                     TAEGRTSQAEQILEQAQTSSEQTSKEQTWSGERMTESGETTEAAVQPTEQSHGGNGQTP
                     DGGSADAGQNSAPKQSAGNHMLAMAERMAASFAGKAQLVWKYGYVQLYRENRAEWIVVF
                     SGLALILWAVYRILAGSITGLLKKGSDSKKIRQLFDGYPVLVGISVLLMIVYAAPFLGL
                     PELIAGSRLCSTEQLFILAVVVIPVDLAAVAIALTPGRRVLPLALAAGVAVIYVGTRQL
                     GIFHGYLYYELTRYNAAVMVTQDITDKFPENSYTIVSTTDELYQVIEQGRHEELLTFLN
                     RVNGSGYTLPTEYIFVYVEKRPIQYAQSHFFTGPDWLAEEKYTSYYTTYFSAGNSINAS
                     EISREQAEKEMMTFSKLSQTYSNLDSRTILESKAYEWCRKFEASYPQEMKVYYEDENFC
                     CYMIRQNTYRLYQLEES"
     CDS             complement(11890..13095)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_5"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg61_12"
                     /sec_met_domain="NTP_transf_5 (E-value: 1.2e-41, bitscore:
                     132.9, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRQQMEEEQWDLCRLLDAALHGRPAEMLPPAEKYEAILELADRHR
                     VLPLLYDVLAPKLPEEDENRKRLEKRSAETVRQSYRLLFLGKYVTGLLREHGIETVLLK
                     GSGTAGLYPVPELRKSGDIDLLVADQKAGEKAYEVLHEHGFRKASEQHAHHHIVCVGTE
                     QIGIEIHVALAEPFDSKSVNEWLAAHQAEFLAHCERTAVMGVEFPVLQPAYHAFYLLLH
                     MLQHFLRAGFGLKLLCDWVVFWEKGYGSGVEEHFCSMAEECRVMGFARLVTAVCVKYLR
                     LSGEKVPLLLCRFDWETEAANLEAFLTEILEAEEFGKSSADRMVALRGTGWRDYCREFH
                     HQMLLTYPGAGRYRILHPVLWVMMFCGFAYRNVKMRRVSGYAVLKKARARGKLVEEMKL
                     FR"
ORIGIN
        1 cgttagcgct cgtctactcc ggcgaggcag ccaccgccat ggagtccaac gccgatctct
       61 cctacacggt tccgaaggag ggatccaacc tctggatcga ttcctggttc attccggctg
      121 acagcacaca caaggaaaac gccgaaaagt ttctggattt tctgtgccgc gaggacgtcg
      181 ccatgctcaa ttttgactac gtctgctacg ccaaatcagg ccgtcgtcga tgcgcttgac
      241 gaggacaccc gcaatgatac cacgatcttt cctcctgacg atgtctttgc gaactgcacg
      301 gtctacaaac agctcggcag cgataccaca gagctttaca gctatctctg gaaacattaa
      361 agtccgaata gcatccgaca tttttagtaa tattgtccaa ttgctttttg actttctata
      421 tgataaatta aatccacata aatgcagcta cgcattcatg tggatttttc ttccccatct
      481 gtacgatttt acttcccctc cattcattcg gaggatttta tgaattacca cgatttcaag
      541 cagcagatca tctctactct ctcggaccgc ctcggctccg atgtccgcat cactgtttca
      601 gacattctca aaaacaacga tacccatctt gacggactca ccattctcgc gcccggtcag
      661 aatctggcgc ccaccattta tctggattac tactatggac agtatgagcg cggcagatcg
      721 ttttccgaca tcacagacga cattctgacc gcctatcggg agaaccgtcc caaatcccct
      781 gttgacatct cttttttcac cgactatgac aaggtaaaat cccgcgtcac aatgaagctg
      841 atcaactatg agcgcaaccg cgaactgtta aagcgggttc cctactatcg ctttttggat
      901 ctcgccatcg tcttcttatg cctggtggaa tctgattctt ccggcacagc aacggtcctg
      961 atccacaatg aacatctcac ttactggggg attaccagag acgacctcta cgccctcgcc
     1021 atggcaaaca caccgcagct gctccgctat gatctgcgca gcatgaccga agttctgcgc
     1081 gagctgtttg cggatgaatt tgcggatcca gcgggaaacg atctcattga gccttttccg
     1141 atctacgttc tgtccaacca gcacaggctc aacggctcct cctgtattct ctatcagcat
     1201 ctgctgcacg attttgcccg gcgcatcggc agtgattttt atattctgcc gagcagcgtc
     1261 cacgaagttc ttctgattcc cgcagacaac cagatcagta tgtccacgct ctcctccatg
     1321 gtccgggacg tcaattcgtc ccagctggcc agagaagaga ttttgtcgga tcacgtctac
     1381 tactactccc tcgagacgga ccagatcact atgtgatcct atggtctgcc cacgatatcc
     1441 tcatacagcc gcgcatacgt ctccgctgac tttttccagg agaaatcctc ccgcatcgca
     1501 cgctccgcaa tgccgttcca gcattttctc tgcgtgtaat acacgcgcat cgcatagcgg
     1561 aggacgccca gcatttcatg cgcattataa ttggcaaagg agaatcctgt gccggtctgt
     1621 tcgtattcat tgtacggcat caccgtatct ttcagcccgc ccgtctcgcg cacgatcggc
     1681 acggttccat agcgaagact catcagctgc gacagaccac acggctcaaa cagcgacggc
     1741 attaaaaacg catcgcagga gccgtagatg cggtgtgcaa gctcctccga gtagccgatc
     1801 gtcacgtgaa tcttctgcgg atatttttcc gcaaaatagc gcagcatctc ctcgtagcgc
     1861 gcctcaccgg tacccgccac cacaagctgc agacgctcgg tgctcatcag ttcatccatc
     1921 acataggcaa tcaggtcaaa tcccttctga tccgtcatcc gggacaccat tccaagtaaa
     1981 aatacgtcct tatccaccgg gagtcccaaa agcttctgaa gctttagctt attgagtccc
     2041 ttcccctccg tgtgattggt ctcgttgtaa tggttcgcca gataggcatc tgtctgcgga
     2101 tcatattccc tgatatcaat gccgtttaag attccataca ggctgccttc ccgggcgcgc
     2161 atcagaccgt ccaatccctc tccaccctcc ggcgtcatga tctctctcgc atatgtgggg
     2221 ctcaccgtcg tgaccgcatc ggcatacacc acaccgccct tcaggtagtt ggcctccccg
     2281 taggactcca gcttatccga agaaaagatc tgctctggca gaccggtaat atctataacc
     2341 gccggcagtg agaaccttcc ctgaaacttc agattgtgaa cggaaaagac cgtgcggata
     2401 ttggaataac atctctgatc cccgtaaaat gtccgcaaga ataccggtac cagtcccgtc
     2461 tgccagtcat ggcagtgaat gacatccggc cagaaatcca gatacggcag cgcctctaac
     2521 accgctttcg agaagaatgc gaacttctcc acgtcctcat agatattgtg atacggctta
     2581 tctcccgcaa agtagaattc attgtccaca aaatagtatg taatgccgtt ctgtaccgtt
     2641 tcaaagatac cgacgtactg tctccgccag ctgagattca catagaaatg gcagacaaac
     2701 cgcagctgtg ccttccactt ttcatccatg cataaatact ttggcatgat aatgcgcaca
     2761 tcaaaatgct tcttatcgaa ataccccggc agcgatccgg tcacatccgc cagaccaccc
     2821 gttttcataa acggcactgc ttccgaagct gcaaataaaa tcttcatcat gtaatcaccc
     2881 ccaggctttt tgatccctct atttattata gcgcttattg tttcttctga aaagtgcgaa
     2941 tcttaccatg cgccgcagcc gcgcggcagg caccataata gctctgcgcg ccggtctgag
     3001 ccatagccac accacactta acatccggta tcccggattc cccacatcca tatagcgtcc
     3061 gtctcttacc gtaccggtca ttttcccctt gacctgctcc cgccgcacgg gtccctcgat
     3121 ggctgtctgg tgatccccca gcagatacag tccgtcctgc ccgatcttat aaatccggtg
     3181 cagtaccagc attccgtttt ccctgcgata aagcacaacg tccccgcgcc gcagcgcgct
     3241 cccatcctct atgccggcaa gtaccacctc gtccctccgc ggatctataa acggatacat
     3301 gctgtacccc tgtggatgaa tctgtatgca tactcccgcc ttaaggagcg gctcaatctc
     3361 atagatctgc tccattcttc ccctcccgtt tctcttcatt cattgtagca ttttttacct
     3421 ctgaatgcta taataagcat acttatgaac cgctaataaa ggagtgacac cggtatgaaa
     3481 ctcaacgatc gatacatcaa ggcaacgctc gcaggtattc cctatctgct tccttacgga
     3541 cagctcatcg cagctcccgc tcctgccacc cggctcaacg attccgggtc acttctgtgg
     3601 gacggcatct tagagggcga tagccgcgag gaactgctcg cccttctcgc agaccgttac
     3661 cataccacag agcgcgagcg cgcggcactt gcggaagatg tcgaccagta tcttcattcc
     3721 ctgtgccgta tgggaattct tcttgcggat acacccgaaa gccggggcga tgatacgcct
     3781 cctcttttct accgcatcgg tcctctggtc ttttcctacc gcggtccctc tctcctatac
     3841 gaccgcttct tctccgcttt ttcctgcgaa gaggaagact tcgaccagga ggttcttatt
     3901 ctgaccggga aaccggcttc cattccttac ggcgccgtgc ttattcacac ggaggaactt
     3961 accatctgcg acagcggaag ttcgtattgt ttcttttttg cagcgccgtg gggcatccgc
     4021 gaaatgcatg taaaaaaaga cggctcacgc gccgtccttt accgtatgcc ggatccggat
     4081 gatatgcaca tcgaagacct gtttcacgca cttcgcttcg cttttctcat cctggctcag
     4141 cagaaggagc tttatgtgct gcactccgcc tcttttttgt accgcgggcg cgcctttctc
     4201 gtttccggca gttccggaac cgggaagtcc acacactctg ccctgtggca tgatctgtac
     4261 cagacgcccc tcttaaacgg cgacttaaac ctgctcggaa tcagagacaa cataccctac
     4321 gcctatggac ttccatggtg cggcacatcg ggcatctgca ccccgaaaga ctatccgctc
     4381 ggcggcatca tcttcttaaa gcaggctgcc atagatcagg tgcagtccct gcagccggac
     4441 gaaaaagtgc tccacatcct gcagcggatg atctcccccg cgtggacaaa ggagcttctc
     4501 cttcgcaatc tgcatttttc cgaagccctc gccccgctca tcttttcctg ccgtctgtac
     4561 tgcacaaaag agccttccgc cgccgggatc ttaaaagccg ccatcgatgc tctttagaat
     4621 tcccgcatca tctgacggat ctcttcctcc tgcatctgca cacacttctg ctcccggatg
     4681 cggtacacct tctgacagat ggacaatacc gtcgggcggt gtgttgtgac gatacaggtg
     4741 ctgggctccg tggtgctcat gatattccgc agcactctgc gctctgttgc gacgtctaac
     4801 gccgaggtcg cctcatccag cagaagaatc ggtgatcggc gaagcagtgc tctggcaatc
     4861 gacagacgct gcgcctgtcc ctccgagaat ccgcctccac gctctccaac catggaatag
     4921 atcccatcgg gaagtttttc cacaaactcc caggcacatg ccgcctttaa cacttcacag
     4981 atttcctcat ccgaggcttc cggtcttaca tttctcatat tttccgcgat tgttcccgaa
     5041 aacatggtat ttccctgcgg cacataggaa aacagccttc ttgcagaggg atccacggca
     5101 atcttctccc cgtctgtctc cccgatcaag gtccgctcgc cctcctgcgg atgcaaaagt
     5161 cccagcatca ggcggagcat cgtcgtcttt ccctctccgg aaggtcccac gagagcgaca
     5221 atctccttgg gacgcgccaa aaagtccgcc ccgcagaata cctgctttcc attgtggtag
     5281 gcatagctta ccccggagaa ggagattccg atgccatccg ttctgtttcg tgcggcgaac
     5341 tgctccacct gatcggcatc cgaaaagtct tcctttggca tatcaagaat gtccatcagc
     5401 cttcccgccg atgtggtcaa agacactgcc gtgggcacca gcgacaccag ctggtttaag
     5461 gttcccgtga gggagcccga cagcgataaa aacatagtca tggtaccgta ggaaatcgcc
     5521 ccgctccaca cccggtagat tccaaacccg taacagctgt aggacaccgc aagtcccacg
     5581 atcgacagca gaattgaggt cgccatggac attttctgaa actccagctt catggtgaga
     5641 tactcccgtt gcagaccgcg cagacgctcc gcgtacagcc ggatcagatc aaaggccttg
     5701 attgtctgga tattggagaa tgcctcctga ttaaagcccg acatctttgc gctcatcgcc
     5761 gcactccgct cattattccc cttcatgcgg cgaagcagcg tcttcgacat cagcatgctg
     5821 accggcattc cgatcagcgc taataacgcg aacatcggat catggtagaa cacgaccgca
     5881 aagatgctga caaaacgcac cgtatagatc acgagattcg gaatccagtt tagaacaccg
     5941 cttgaaatat tggaggcatc cgaactccag cgcgttaaaa gatctcccgt gtggtagttc
     6001 tggattgact ccagatccgt caacagcatt ttttcaaaaa tatccgcctt gatggcattg
     6061 tccacgctga tgctgatctt gttcgcaaag taattggaga tctgggaaat caggacattt
     6121 ccaaccgaga acccgatata gaggcagaag gtgcgcgcca gaagccccgc ctgctgtcct
     6181 gtgataatat ccaccatatc gcgggaaatg agacttgaaa tgagcgatac cagcgttccc
     6241 gcaagtccca gaagcgtata aaatatcatc tgcttccaat aaagtctcgc atattcgtag
     6301 atccatagcg tctgtctcca catatcacgg agcattccct ctttgatccg ctctctgtaa
     6361 tgtctgaact tctcaagcat tgtaattttc ctattctttc ataaaaatga attctgtctg
     6421 caggattctc cgcctgcggc gggtcgctct tgcgacatct ttcgtctccg ccgcagtgcg
     6481 atccctggag agttttttat gtaataggaa agaagtttcc tattacataa aaaagagctt
     6541 cacaggagga accgattcct cccgcgaagc ttttgacttc tcacatccgc ccggtcgcct
     6601 gccggcttct taatctgtaa tgttcacgct tgtcaccgca agccccgcat ctgcctgcac
     6661 aaccagatcc ccgagtccga tattgtcggt cggattctga tgatagttat aattgatcac
     6721 aagtgtattc gttccgctgc cggataccag tgatccgccg gaactagtgt aggttaccgg
     6781 aagactgaac gaaatggtca gtgtctgcgc ctctttcgta tgatcggcac tgtgctgacc
     6841 gtttacctgg atacggtact ccccgcttcc ggactgcggt gtctgatgaa tgtacgcgct
     6901 cgccgtatag catccgcttg caagatagac cccttccgca agttcttctg ttctaagaat
     6961 cacaggactc tcataattcg tcatagcatt tcccccgttt taaagattgt tacatgttcc
     7021 agtctgtgac cgcatcatcc ggaccatagc ccttcttctc ccatgacggc ttacggttac
     7081 cattatccac atcgtaactt cccgcatacc cggaatccac ataatggctc aacagaccgc
     7141 agccggaagc agtattcgcc gggcatccaa gacatccgaa ctgctgcttg tatccgcgtg
     7201 tggtgccatt ccagtcggaa taatccggcg cctgccacac accgttcatg tagacactgt
     7261 cacacttgat gcctccgctc gcaagataaa ccccctctgc aagctcctcc gtccgtatca
     7321 tcaccggact ctcataattc gtcataaaac cagccacctt ctaacacttt tttgcggcac
     7381 ttctgccgct gactcataca catattttaa gtataatatt ctgtgtttgc gctgtcaagc
     7441 atgaattttc tgccagaacg gcatgccggc attttctcta ccagaccatg gtatccgggg
     7501 tcagtccctg ctgttcccag acaggctgat agacatttcc ggcgactttt gcatcaccct
     7561 tttgcagctt gcagccgtca ccgtcatccg ccgcacagcc ctcgcagcct tttctgtcat
     7621 aggcacgcat ctgcacattg ctgttgctgt aatccggctt tttccaggct cccttcatgt
     7681 accggctgtc acatccacct gccgtcggat cttccccggt ctgtccgccg cttgccagat
     7741 agacgccctc cgaacattcc gtcatcaaaa tcacttccgg tttttcatag ttctgcataa
     7801 gaaaccacct tccacaatcc caccacatac aggattcttt ttcttttcat ttatagtggt
     7861 ttctgcggcg tgattcctcg tacaaacttg tgatttcttg tacgattttg cacttgtaag
     7921 cctttgtact tgcatcgttg tgcacctatc gcactgccac ctcaccgagg cagtatccgt
     7981 tttctgtggc atccgcttcg tttgcaagta aaatctgttc cccgctgtct gcatcgctaa
     8041 gattgatata tacccggtaa gtcccgctct cccagccgcg gatcggaatg gttccggtga
     8101 gcgccagttc cctgtcgtcc tcatttccac cggaaagctt aagtagtttc tcttcccatt
     8161 catccgtata gcagactgcc cccgcctcat ctgtaacgct cacacagact tttgtctgcc
     8221 ggtaaaacgg tgcaaacccg ctgtttttta aagcagcatt tacctccacc gtatccgccc
     8281 agaacgaatg gctcaaagcg gcaccggcaa tccacagacg gtaccccaga tgccgttcca
     8341 cataagacca gccgtccatt ccgtcgtagc agtcatctgt attcacgacc gttcctgccc
     8401 acttatccag gacattcctg tcatagtcct cgtttaagta actcacatgc atggttttta
     8461 aatccgcgat cgcattttca agatcattgt acgggttatc gacaatcact tccccgccgg
     8521 acggcacact gctgcacaat acatcctgaa atgacagttc ttcctcccgc gtccacgccg
     8581 aaaaatcccc ggcgtcctgt ctggtgttat cgctgtaagt tccgtaatcg ctcacgcttc
     8641 ccagcatgcc gtcattaaaa agtccaagcc ttttggctag cgggttctct gtccagccgt
     8701 ccggtgccgc ctcccccgtg atttttctcc actgcgccgg cgtccgcacg gagagaaacg
     8761 tggacgcatc gctcacatcg gcaaggcgtg ccgccagttc tctcatggaa tccgggtccg
     8821 tgtattttgt tccgttcatc tccccccagt tgccgataaa gagtccctga agcgtataga
     8881 tacagctgtg atactcccga agcacatctc ccacctgctc catatgctgc aatataatgt
     8941 caagattctc cggttcatac tgctcgttct ccccgttcca gtcatagagg aaacggacga
     9001 tccatttctt gtcgctgtcc gccatggctg caaacaactg ccggacattg gacagcccct
     9061 cctccgatat ggcacccgtc cggtattccc gcagattgat ctgcatcatt ccaagccgcg
     9121 tcgcgtcatc ttccctcgtc ctgtctctta aatctgtggc atagtcgacc ggttcatccg
     9181 taatgcggta gccgtaaatg taataaaatc cgcggtccgg attggaaagc ctcctggatg
     9241 actctgcaaa cgccgccggc gtacatgtca ccttccagtg aaacaggctg cccattgcag
     9301 ccgctgctgc aaggcacaaa acaactgcca cgccaagcgc caaaaacttt tttccacgtc
     9361 cactcatgat tcctccagct gatataaccg ataggtgttc tgccgtatca tatagcagca
     9421 gaaattctca tcttcataat ataccttcat ctcctgcgga taggatgctt caaacttcct
     9481 gcaccattcg tacgctttgg attccagtat cgtgcggctg tccagattgg aataggtctg
     9541 cgagagtttt gagaacgtca tcatctcctt ctctgcctgc tcccgcgaga tctccgaggc
     9601 attgatgctg ttccccgcgc tgaaataggt cgtatagtaa gaagtgtatt tttcctctgc
     9661 cagccagtcc ggtccggtaa agaaatggct ctgtgcgtat tgaatcggcc gcttctccac
     9721 atacacaaaa atgtattccg tcggcagggt atagccactt ccgttcaccc ggttcaggaa
     9781 agtcaaaagc tcctcatgcc gcccctgttc gatcacctgg taaagttcgt ccgtggtaga
     9841 cacaatcgta tagctgttct ccgggaattt atccgtgatg tcctgtgtca ccatcaccgc
     9901 cgcattgtat ctggtcagtt catagtagag gtatccgtga aaaatgccaa gctgtctcgt
     9961 ccccacatag atcaccgcca ctcccgcggc aagcgcaagc ggcagcacac gtctgccggg
    10021 cgtaagggcg attgccacgg cagccagatc caccggaatg accacgaccg ccagaatgaa
    10081 aagctgctcc gtagaacaaa gtctggaacc tgcgataagc tccggcagcc cgaggaacgg
    10141 cgccgcatag acaatcataa gcaataccga tattccgacc agcaccggat atccgtcaaa
    10201 cagctgccgg atctttttgc tgtcacttcc cttttttagc aggccggtga tactccccgc
    10261 aagaatccgg tacaccgccc agaggatcag tgccagaccg ctaaaaacca caatccattc
    10321 cgcccggttc tcacggtaca gctgcacata cccgtatttc cagaccagtt gtgccttgcc
    10381 ggcgaacgat gccgccatcc gttctgccat cgcaagcata tgattaccgg cagattgttt
    10441 cggagcgcta ttttgtcccg catccgcact cccgccatcc ggtgtctgcc cgttcccccc
    10501 gtgggattgt tccgtcggct gcaccgccgc ttctgtcgtc tccccgctct ctgtcatcct
    10561 ctcaccggac catgtctgct ccttcgatgt ctgctcactc gatgtctgcg cctgttctaa
    10621 gatctgttcc gcctggctgg tacgcccctc cgcggtatcc gtaccgttta tgacattgac
    10681 cgcccatccg atcgatccct ggaacggtac acccttcgca tacgcaattc ccatcggcag
    10741 caccgctatc agcacaccga ggcagaccgc ctttacgaga gatacaaacc ttctcttttg
    10801 aaaaagagag ggaagcctgc acgcggcaat caccacgcag aggaaaaacg ccatcatcgt
    10861 gacataaaaa tgaatggcaa gggaagccgc cagtgacagc agaaacagca gcagattctc
    10921 ctccgtcaaa aactttctga tccgctctct ccggctaccg gatctgtcgc taaagtccgt
    10981 cttaaggcag cgaagcagaa acagtgcgca caggaattgt gtatacagtc cgaactcctg
    11041 cggcagcgtc cactgcagac gggacatgga aaagatctcg tcaatgcaca aaagatccac
    11101 ggtcaggaac aacgccagtg caagcaccgc ggttccatcc catgcaaata attccttcag
    11161 cagcagatac gcgctgacca gaaaaaccgc gacgtggatt cccgccagaa acagctggct
    11221 gctgtaaatc tttaccccga acagcacgcg catggcgtag ataaagcagt gcatagcttc
    11281 cgggtagatt ccctcataaa aaggcgtacc gtttaacagc ccgtagatcc acgagtggtg
    11341 gcggtacata tcgccaaacc cgtaggagta atcatggaat gccccgtagg aaaaatacac
    11401 catgccaaag cacacaacca cccccagcat cagatagacg cagcgccgtc cccgtatgct
    11461 ctgcctgaat tgtgcatgta catgcccgat cccgtctttt actctgttgc gcaggcgaag
    11521 cagcaaaagc cggatgccgt aggttcccag aaacaggcgg gagatctttt tgatctgctc
    11581 ccgccgcacg gggtgccatc ttagcaagcc aagcagcaat gtgccgtaaa acagcacggc
    11641 aatcagccat ccgtacagta tatgaaacac gcccagactt agtaccaccg tattgagcag
    11701 cacaaccgga accgtcacac agaaagcaaa ccgcaccgtg cggcttctgc ctcttaagta
    11761 gtcccggaat accacagacg gccacacaaa cagaatcatc acataggcaa aaaataccct
    11821 gacatattcc agtgcccagt accatgtatc cattttgctc tcctcctttc ccgtcgaaca
    11881 tcctattttc tagcggaaca gcttcatctc ctccacaagc tttccgcgcg ctctcgcctt
    11941 ctttaacacc gcgtaccccg atacccggcg catcttaacg ttgcggtatg caaaaccgca
    12001 gaacatcatc acccacaaca ccggatgcag aatgcggtag cgccctgccc ctggataggt
    12061 gagcagcatc tgatgatgaa attccctgca ataatcccgc cagccggttc cccgcagcgc
    12121 caccatacgg tcggcacttg acttgccgaa ctcctccgcc tccagaatct ctgtcaggaa
    12181 tgcttccaga tttgcagctt ccgtctccca gtcaaatcgg caaagcagca ggggcacttt
    12241 ttccccggaa agtctcagat attttacaca gaccgccgtc accagacgcg caaatcccat
    12301 cacgcggcat tcctctgcca tggagcaaaa atgctcctct accccgctgc cgtatccctt
    12361 ttcccagaat acgacccagt cgcaaagcag ctttaacccg aatccggcac gcaggaaatg
    12421 ctgcagcata tgaagcagca ggtaaaacgc atgatatgcc ggctgcagca ccggaaactc
    12481 cacccccatc accgccgtcc tctcacagtg cgccagaaat tccgcctgat gtgcggcgag
    12541 ccactcgttg acgcttttgg agtcgaacgg ctctgccagc gcaacgtgaa tttctattcc
    12601 aatctgctct gtgccaacgc agacgatatg atggtgtgca tgctgctctg aggctttccg
    12661 gaatccatgc tcatgcagca cctcatacgc cttttctccc gctttctgat ccgcaacgag
    12721 cagatcaata tccccagact tgcgaagttc cggcaccgga tagagtcccg ccgtgccgct
    12781 cccctttaaa agaaccgtct cgattccatg ttcccgcaaa agtcctgtca catatttccc
    12841 gaggaacagc aggcggtagc tctgccgcac tgtctctgcg cttctcttct caaggcgctt
    12901 ccggttctca tcctcctcgg gcagcttggg tgccagcacg tcgtacagca gcggcagcac
    12961 gcgatgccgg tctgccagtt caagaatggc ttcgtatttt tcagccggcg ggagcatttc
    13021 cgccggtctg ccgtgcagcg ccgcatccag cagcctgcac aaatcccatt gttcttcttc
    13081 catctgctgt ctcatcacat tcctccccga tgcagcctgc cccactcgat gcgccgcagg
    13141 cgctccaaca cccgtttcca ttctttcgtc ctgccgtatg ccataaaaaa caacagattg
    13201 ggcagcacca cacagagtgg cagccggatg agaagaacgg taagcggact tccctctgcc
    13261 agtccgcaga ccaggtctgt cacaatccat accgctccca cacagaccgc atacaaaagg
    13321 tagcgcagat aaaaccggtg caccggcaga tgcagtcttc tccggtacag gacaaacggc
    13381 tccacccaca ccgacgtgag aatcgttgac aaaaacgttc cgataaatac gccgagcgtc
    13441 tgatactgtc ttaccagaag aatcgacagc accagattga gcgccgcctc cgccagcgcc
    13501 ttgtagcgat cgaaccagaa caatcccatg gaatcccgaa aggtcagcac cgctttcctg
    13561 gttccgttga taaaaaagtt gaggcataag atcatgacaa cggagcgttc aaacagatac
    13621 tgtctgccaa aagccagctc cacaaacgga ttgagcaatt cgtacaggca gatcgccgca
    13681 aacccgtaaa gccactgccc gataaaaaag gccgtctcaa aaatctcgcg gattttgccc
    13741 tggtcctccg ttgctcccag attgcccaca ctcgctgtaa ttcccgcaaa gacctggtcc
    13801 aacacctggc ggacggaacc gatcagaaga taataattgg aatatattcc gacactgacc
    13861 acgtcgacaa acgcggagat cagtaaatta tcggtattat ttacaacgac cgtcccaagc
    13921 ttgtgcatca tcatggcgcg gatattctga aacagtcccg tccgctcctc tgcgggaaga
    13981 cgttccttct ctttttcctt taaatacggg aaaagctttt ccgcctttcg cgagatacac
    14041 acatttgaca gaaccgtgca catcagatac atcagcaaaa acagaataaa gtttcccgta
    14101 gtaagcagca caacaatctg cagcagatcc tgcagcacca gaaagccggt ctgatagatg
    14161 agcaccacat aattcatctg atgcgcctca atcagcgtcc tctggtacac cagcagatac
    14221 gacagcacgg agttggcgag atagagaagg taaataaacg tcagatgctc cacctcgggt
    14281 ctgtttttca tgagcacgtc cataaacgga atcagcgcca gtcccagcac gcccacacac
    14341 accgcggttc cacggtaaaa tgtctggtaa agcttcatca gctgctgctg ctttttgatg
    14401 ttgccctccg cgatcggccg gtacaaggcg taagtgattg ccgtgcctgc gccaagctcg
    14461 gtcaacgaaa gcacgtttaa aatatcggtg aacagaccgt tgattccgac atagttttca
    14521 ctcagcgtat gcgtaaaaat cacacgcgtc acaaatccca tcagaatcgc cgtcattctg
    14581 gagatgaccg ccacggttgt attcattgcc gaatatt
//
