LOCUS       c00064_gnlPro..        10380 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AIJFIDOP_64.
ACCESSION   c00064_gnlPro..
VERSION     c00064_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 17:20:26
            Original ID  :: gnl|Prokka|AIJFIDOP_64
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10380
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..99)
                     /locus_tag="ctg64_1"
                     /transl_table=11
                     /translation="MLPFSKLFRVRNFLTENFVIFAYSNFKKATTMF"
     protocluster    1..10380
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[5241:9458]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      5242..9458
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..10380
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..10380
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             168..734
                     /locus_tag="ctg64_2"
                     /transl_table=11
                     /translation="MKKNLLYLWALVCSLTLFAACSSDDDDSDNKNNENPPEEEAVITA
                     PDVIGTYWGNLDISMIPDGSDQEIVIGDGIEKFITLSQVSNTEVKIELKDFELFINQQI
                     LKFGDIVIDKCEVKKGEGVSTFTGQQDLTFEGDAASLGTCPVTVTGTVEGGNADMTINV
                     KVPALQQTVKVTYSGVKQVAEPSGT"
     CDS             complement(731..1516)
                     /locus_tag="ctg64_3"
                     /transl_table=11
                     /translation="MKIYPYIFSLLTCIGIALPGYAQVDRNETLIRSALHGLEYEIKAG
                     FSIGGTAPLPLPVEIRSIDGYNPTLAISIGGEVTKWIAVQNKLGIIVGLRLENKAMTTE
                     ATVKNYNMEILGQGGERISGVWTGGVKTKVHTAGLTIPLMATYKLTNRWNIKAGPYFSY
                     LLSREFSGHVYEGYLREDNPTGPKVEFTDGKIATYDFSDDLRHFQWGLQIGAGWRAFKH
                     LNVYADLTWGLNDIFKNDFNTVTFAMYPIYLNIGFGYAF"
     CDS             complement(1549..2634)
                     /locus_tag="ctg64_4"
                     /transl_table=11
                     /translation="MKAKHVILYLLLAIVSFSCIGEEALNAEADILSCALPGVAMTTSP
                     IINNNSITIFVGPGTDISELTPEFTLTPGATINPLSGTERNFNTPQEYTVTAADGVWKK
                     TYIISVIDTELATNYNFEDTLGGKKYYIFVEREGGKVVMEWASGNAGYAMTGVAKTADD
                     YPTFQITDGKAGKCLSLVTRSTGFFGQIAGMPIAAGNLFIGSFDVSNAMSNPLKATKFG
                     LPFRHVPTYLAGYYKYKAGDQFTEGGKPVNGKRDICDIYAIMYETSESVPTLDGTNAFT
                     SPNLISTARINNAKETNEWTYFKLPFTTLPGKFIDKEKLMDGKYNIAIVFTSSLEGDHF
                     NGAIGSTLLIDEAELIYHSED"
     CDS             2768..4054
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SDH_alpha"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg64_5"
                     /sec_met_domain="SDH_alpha (E-value: 1.9e-63, bitscore:
                     204.2, seeds: 645, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTESERRQIIELIKKEVIPAIGCTEPIAVALCVAKAAETLGVKPE
                     KIDVLLSANILKNAMGVGIPGTGMVGLPIAVALGALIGKSDYQLEVLRDCTPEAVEQGK
                     RFIAEKRICISLKEDITEKLYIEVICKARDKTAKAIIAGGHTTFIYIAKDEQTLLDKQH
                     TVSEEEEDASLELNLRKVYDFALTAPLDEIRFILDTARLNKAAAEQAFKGNYGHSLGKM
                     LRGTYEHKVMGDSVFSHILSYTSAACDARMAGAMIPVMSNSGSGNQGISATLPVVVFAE
                     ENGKSEEELIRALMLSHLTVIYIKQSLGRLSALCGCVVAATGSSCGITWLMGGNYNQVA
                     FAVQNMIANLTGMICDGAKPSCALKVTTGVSTAVLSAMMAMEDRCVTSVEGIIDEDVDQ
                     SIRNLTRIGSQAMNETDKMVLDIMTHKGC"
     CDS             complement(4182..4760)
                     /locus_tag="ctg64_6"
                     /transl_table=11
                     /translation="METVENKYITVAYKLYTMEDGEKELFEEAKAEHPFQFISGLGTTL
                     EDFENQITALSKGDKFDFTIPADKAYGQYDEQHVIDLPKNIFEIDGKFDSERIKEGNIV
                     PLMTGDGQRVNASVVEIKPDIVVVDLNHPLAGADLIFEGEILESRPATNEEIQELVKMM
                     SGGDGCGCGCDSCGDGCGDDCGCEGGHCH"
     CDS             5242..7041
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg64_7"
                     /sec_met_domain="ILVD_EDD (E-value: 2.7e-217, bitscore:
                     712.0, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKQLRSSFSTQGRRMAGARALWAANGMKKNQMGKPIIAIVNSFT
                     QFVPGHVHLHEIGQLVKAEIEKLGCFAAEFNTIAIDDGIAMGHDGMLYSLPSRDIIADS
                     VEYMVNAHKADAMVCISNCDKITPGMLMAAMRLNIPAVFVSGGPMEAGEWNGQHLDLID
                     AMIKSADESVSDQEVANIEQNACPTCGCCSGMFTANSMNCLNEAIGLALPGNGTIVATH
                     ENRTQLFKDAAELIVKNAKLYYEEGDESVLPRSIATRQAFLNAMTLDIAMGGSTNTVLH
                     LLAIAHEAEVDFKMDDIDMLSRKAPCLCKVAPNTQKYHIQDVNRAGGIIAIMDELAKGG
                     LIDTSVRRVDGMSLAEAINEYSITSPNVSEKAIKKYSSAAGNRFNLVLGSQGMYYKELD
                     KDRANGCIRDLEHAYSKDGGLAVLKGNIAQDGCVVKTAGVDESIWKFTGPAKVFDSQEA
                     ACEGILGGRVVSGDVVVITHEGPKGGPGMQEMLYPTSYIKSRHLGKECALITDGRFSGG
                     TSGLSIGHISPEAAAGGNIGKIVDGDIIEIDIPARKINVRLTDEELAARPMTPVTRDRY
                     VPKSLKAYASMVSSADKGAVRII"
     CDS             complement(6966..7115)
                     /locus_tag="ctg64_8"
                     /transl_table=11
                     /translation="MTVENEWFTIIALSAAQLTITYQLYYIILTAPLSAELTMLAYAFR
                     LFGT"
     CDS             7156..8850
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg64_9"
                     /sec_met_domain="TPP_enzyme_C (E-value: 3.7e-48, bitscore:
                     152.9, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDLITGAEALMRSLEHQGVTTIFGYPGGSIMPVFDALYDHQNIL
                     NHILVRHEQGAAHAAQGYARVSGDVGVCLVTSGPGATNTVTGIADAMIDSTPIVVIAGQ
                     VGTGFLGTDAFQEVDLVGITQPITKWSYQIRRAEDVAWAVARAFYIARSGRPGPVVLDF
                     AKNAQVEKTKYEPTKVDFIRSYVPVPDMDEETVQAAAELINNAERPLVLVGQGVELGNA
                     QSELREFIEKADMPAGCTLLGLSALPTEHPLNKGMLGMHGNLGPNINTNKCDVLIAVGM
                     RFDDRVTGNLATYAKQAKVIHFDIDPAEVNKNVKVDVAVLGDCKETLASVTKLLKKNTH
                     TEWIDSFKEYEKVEEEKVIRPELHPATNSLSMGEVVRAVSDATHHEAVLVTDVGQNQMI
                     SARYFKYTKERSIITSGGLGTMGFGLPAAIGATFGAPERTVCVFMGDGGLQMNIQELGT
                     IMEQKAPVKIICLNNNYLGNVRQWQAMFFNRRYSFTPMLNPDYMKVASAYDIPSKRVFT
                     REELKEAIAEMLATDGPFLLEACVVEEGNVLPMTPPGGSVNQMLLEC"
     CDS             8901..9458
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg64_10"
                     /sec_met_domain="ALS_ss_C (E-value: 2.4e-19, bitscore:
                     59.1, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDKTLYTIIVHSENIAGLLNQVTAVFTRRQINIESLNVSASSIK
                     GVHKYTITAWTDKDIIEKVVKQIEKKIDVIQAHYFTEDEIYFHEIALYKVSTPAFQENP
                     EASKLIRRYNARIVEVNPVFSIVEKNGMSEDITSLYGELKALNCVLQFVRSGRVAITTS
                     CFERVNEFLDGREAMYNQSKNQ"
     CDS             9464..10207
                     /locus_tag="ctg64_11"
                     /transl_table=11
                     /translation="MSEENRIGTYQFVAEPFHVDFNGRLTMGVLGNHLLNCAGFHANDR
                     GFGIATLNEDNYTWVLSRLAIELDEMPYQYENFSVQTWVENVYRLFTDRNFAIIDKDGK
                     KIGYARSVWAMINLNTRKPADLLTLHGGSIVNYVCDEPCPIEKPSRIKVTSDQSIATLT
                     AKYSDIDINGHVNSIRYIEHILDLFPIELYKTKRIRRFEMAYVAESYFGDELSFFCDEV
                     NANEFHVEVKKNGNEVVCRSKVIFE"
     CDS             10275..10379
                     /locus_tag="ctg64_12"
                     /transl_table=11
                     /translation="MAQLNFGGTTETVVIRDEFPLEKAREVLKNETIAV"
ORIGIN
        1 aaacatagtt gtggcttttt taaaattact atatgcaaat ataacaaagt tttcggtaag
       61 aaagttgcga actcgaaata acttcgaaaa aggaagcata ttgaaccttt tttcttcttt
      121 ttagtttata aaggacgaat ttattgtaat aactaaacca aagacgtatg aaaaagaatc
      181 tattgtattt atgggcattg gtatgttctc ttactctctt tgctgcttgt agcagtgatg
      241 acgacgatag tgataacaag aataatgaga atcctcccga agaggaagct gtgataacgg
      301 ctccggatgt aatcggaacg tattggggaa atctggatat atccatgata ccggatggct
      361 ccgatcagga aattgtcatc ggcgacggaa tagagaagtt tatcacgctt tcgcaggtca
      421 gcaatacgga agtgaagatt gaactgaagg attttgaatt gttcatcaac cagcagatat
      481 taaaatttgg agatattgtc attgataaat gtgaagtgaa aaagggggaa ggtgtgtcta
      541 cattcaccgg acagcaagat cttacatttg aaggagatgc tgcctctttg ggtacttgtc
      601 ctgtaacagt tacgggaact gtagaaggtg gaaatgcaga catgactatt aatgtgaaag
      661 tgcctgcatt gcaacagacg gtgaaagtaa cctactccgg agtgaagcag gtggcagagc
      721 ctagtgggac ttaaaaagca tacccgaaac ctatattcaa gtagatgggg tacatggcaa
      781 aagtgactgt attaaaatcg tttttaaata tatcattcaa tccccaggta agatcggcat
      841 acacattgag gtgcttgaag gctcgccatc cggctcctat ctgtaatccc cactggaaat
      901 gtctcaagtc gtccgagaaa tcgtatgttg caattttacc gtcggtaaac tcaaccttcg
      961 gaccggtggg attatcttcc cgcaaatatc cttcgtatac gtgacctgaa aattctcttg
     1021 aaagtagata ggagaaataa ggcccggctt tgatgttcca ccggttggtt agtttgtagg
     1081 tagccatcag aggtattgtc agtccggcag tatgtacttt ggtttttact ccgcctgtcc
     1141 atactccgct gattctttca cctccctgcc cgagaatctc catattgtaa ttcttcacgg
     1201 tggcttcggt agtcattgct ttgttttcaa gtcgcaatcc gactataatt ccgagcttgt
     1261 tctgaacggc aatccatttg gtcacttcac ctcctatact gatagctaat gtcgggttat
     1321 atccgtcaat ggaacggatt tccaccggaa gaggaagcgg ggctgtgccg ccaatgctga
     1381 aacctgcttt tatctcatat tccagtccgt gaagggcgga acggatcagt gtttcatttc
     1441 gatcaacctg tgcatagccg gggagggcta ttcctataca ggttagtaaa ctgaatatat
     1501 acggatagat tttcatcgtt tttgttgtta taaagttatt tagttccact aatcttccga
     1561 gtgatagatt aactcggcct cgtcaatgag caacgtactt ccgattgctc cgttaaaatg
     1621 atctccttcc agacttgagg tgaacactat ggctatatta tattttccat ccattagctt
     1681 ttccttatct atgaatttgc cggggagagt ggtgaaagga agcttaaagt aagtccattc
     1741 gttcgtttct ttggcattat taatccgtgc tgttgaaatc aggtttgggc tggtaaatgc
     1801 gttcgttccg tcaagggttg gaacagattc gctggtttca tacatgatgg catatatgtc
     1861 acagatatcc cgtttcccat ttacaggttt gcctccttct gtaaactgat ctcctgcttt
     1921 gtacttataa tagccagcca gataagtagg tacatgccgg aaaggaagac cgaatttagt
     1981 tgctttaagc ggattactca ttgcattgct tacatcaaag gaaccgataa acagatttcc
     2041 tgccgcgata ggcattcctg ctatttgtcc aaagaatccg gtactgcgtg tcactaaaga
     2101 aaggcatttg ccggcttttc cgtccgttat ttggaaagtg ggatagtcat cagcagtttt
     2161 ggctacgccg gtcatggcat agcccgcatt tccgctggcc cattccataa cgactttacc
     2221 tccttcgcgt tctacaaata tgtagtactt ctttccgcca agcgtatctt cgaaattata
     2281 gttcgtggca agttccgtgt cgataacgga tatgatatac gttttcttcc aaacaccatc
     2341 ggcagctgta acagtatatt cttgtggagt attgaaattt cgttccgtac cgctaagagg
     2401 attaattgta gctcccggag tcaatgtaaa ttcaggtgta agttctgaaa tatcagttcc
     2461 cggaccgacg aagatagtga tggaattatt gttaataata ggactggttg tcatggctac
     2521 tcctggtagt gcgcaactta atatgtctgc ttctgcattg agagcttctt cgccgataca
     2581 ggaaaaggaa acaatagcca gtagcaaata gagaatcacg tgttttgctt tcatttttct
     2641 atcaattctt tctgttaaag tttggtgtat gggagatttt ataacaatat gagattttat
     2701 ttgttcatta tagaatgttg gaaaagaaag attttcctat ttttgtggaa ccaaaactta
     2761 taagtccatg actgaatcag aaagaaggca aattatagag ttgattaaga aagaagtcat
     2821 tccggctatt ggatgtacgg aacctatcgc agtagcgctt tgtgtagcta aagctgctga
     2881 aacgttggga gtgaaaccgg aaaagataga cgtcttgcta agtgctaata tactaaagaa
     2941 tgccatggga gtcggaatcc cgggaacggg tatggtaggc cttcccatag ctgtggcttt
     3001 aggtgcgttg attggcaaat cagactatca gttggaggtg ttgagggact gtacgccgga
     3061 agcagtggaa caggggaaac ggttcattgc agaaaaacgg atttgtattt ctctgaaaga
     3121 agatattacg gaaaagcttt atatcgaagt gatttgtaaa gcgagagata aaacagctaa
     3181 agctatcatt gccggtgggc atactacctt tatatatata gccaaagatg aacagacatt
     3241 gctcgacaag caacatacag tcagcgagga agaggaagat gcttcgctcg aattaaactt
     3301 gcgtaaagtc tatgactttg cactgactgc tccgttggat gagattcgtt tcattcttga
     3361 tacagcccgt ttgaataaag ctgctgccga gcaagccttt aaaggtaatt acggacattc
     3421 tttaggtaaa atgcttcggg gaacttacga acataaagtg atgggtgaca gcgtattttc
     3481 tcatattctc tcttatacat cagctgcttg cgacgcccgg atggcgggtg caatgattcc
     3541 tgtcatgagt aattccggca gtggtaatca ggggatatcc gctacactcc ctgtcgttgt
     3601 ctttgccgaa gagaacggaa agagcgaaga agaacttatc cgtgctttaa tgttaagcca
     3661 tctcactgtt atatatatca aacaaagttt aggacgtctg tcagctttgt gtggctgcgt
     3721 ggtagctgct accggatcca gttgtggaat cacctggttg atggggggaa actacaatca
     3781 ggttgccttc gccgttcaaa acatgattgc taatctgaca ggaatgattt gtgacggtgc
     3841 aaaaccgagt tgtgcattga aagtaactac cggagtttcg acagccgtat tatctgcaat
     3901 gatggcaatg gaagaccgtt gtgtgacttc cgtagaggga attatcgacg aagatgtaga
     3961 tcaaagtatc cgcaacctga caaggatcgg ctcgcaagcc atgaacgaaa cggataaaat
     4021 ggtgcttgac atcatgacgc ataaaggatg ctgatttcaa gtattaagta tcaggtatta
     4081 agtattagct caaataacgg cataaaaaaa gtattaagta ttaaagcccg gctgtgtccg
     4141 cacggaatta atacttaata ctttataatt taatacttta tttagtgaca gtgtccgcct
     4201 tcgcaaccgc agtcgtcgcc acagccatca ccgcagctgt cgcatccgca accacagcca
     4261 tcaccaccac tcatcatttt cacaagttcc tgaatttctt cgttcgtagc aggacggctt
     4321 tccagtattt caccttcaaa gatcaggtcg gcaccagcca acggatggtt gaggtcaact
     4381 actacaatat ccggtttgat ttctactacg ctggcattta cgcgttgacc gtcaccagtc
     4441 atcaaaggta cgatgttacc ttctttaata cgttcgctgt caaatttgcc atctatttca
     4501 aatatatttt tggggaggtc aatgacgtgt tgttcgtcat attgtccgta agccttatct
     4561 gccggaatgg taaagtcaaa tttatcacct ttagaaagag cagttatttg attttcgaag
     4621 tcttcgagtg ttgttcctaa tcctgaaatg aattgaaagg gatgttctgc ttttgcttct
     4681 tcgaacaact ctttttcacc atcttccatt gtatatagtt tgtatgcaac ggtaatgtac
     4741 ttgttttcta ctgtttccat ctgatatttt ttgtttctga ttaataattc ccggtaatcc
     4801 gggtcgacaa agatacgaat tatttgcttg tcctctggta tagggagggt aaatttcaga
     4861 ttattaagtg cttttgtcag aaaaagaagg tggagtgtgc acttagataa tagttgtaaa
     4921 ttcaaccttt aagtgataaa atagagaaat aatacctctc ttttcttaca attattcgct
     4981 tttaagtgat ttttttcttc gatttgtttg gatataataa aaaagccctt acctttgcag
     5041 cacgaaaata aagaaaagaa gatatgaata tgttacatac atctattaac ctagcagtcc
     5101 tgcatattat tcgcgtcgtg gtggtcccat caagagcgtg agaaaggttt ttgtgttgta
     5161 tgtgttcgta ccataaaaga tagaatttag agcctttctc acttgtgtga ggaaggctct
     5221 ttaattaaaa gatagattga aatgaaaaag caattacgca gttcgtttag tacacaaggc
     5281 cgtcggatgg cgggagcccg tgcgttatgg gcagccaacg gcatgaagaa gaatcagatg
     5341 ggtaaaccca ttatcgctat cgtcaattcg ttcacccagt ttgttccggg acatgtgcat
     5401 ctgcatgaaa tcggtcagct ggtgaaggca gagattgaga agctgggatg cttcgctgcg
     5461 gaattcaata caatagctat cgacgacggt atagcaatgg gacatgatgg tatgctttac
     5521 tcgcttcctt cacgtgacat cattgcagac agtgtagaat atatggttaa tgcgcacaag
     5581 gcagatgcaa tggtatgtat cagcaattgc gataagatta ctcccggaat gttgatggcg
     5641 gctatgcgtt tgaatattcc tgccgtattt gtatcgggcg gtccgatgga agccggagaa
     5701 tggaatggtc agcacctgga tttgatcgac gcgatgatta aatcggctga tgaaagtgtc
     5761 agcgatcagg aagtagcgaa tatcgagcaa aatgcttgtc ctacttgcgg atgttgttcc
     5821 ggtatgttta ccgccaattc aatgaactgc ctgaatgaag caatcggact ggctcttccc
     5881 ggaaacggaa ccatcgtagc tacacacgag aatcgtacgc agcttttcaa agatgcagca
     5941 gaactgatcg taaaaaatgc aaagttatat tatgaagaag gagacgaaag tgtgcttcct
     6001 cgtagcattg ctacccgtca ggctttcttg aatgccatga cgctggatat agcaatgggt
     6061 ggttctacta atacagttct tcacctgttg gctattgctc atgaagcaga ggtagatttc
     6121 aagatggatg atatcgatat gctttcccgc aaggctcctt gtctctgcaa ggtggctccc
     6181 aatacacaga aatatcatat tcaggatgta aaccgtgccg gtggtattat tgctatcatg
     6241 gatgaactgg caaaaggcgg tctgatagat acatctgttc gacgggtaga cggaatgtca
     6301 ttggcggaag ctattaacga atattcaatc accagcccga atgtaagcga aaaggcaatt
     6361 aaaaaatatt cgagtgcagc cggaaataga ttcaatctcg tacttggttc acagggcatg
     6421 tactataagg aactggataa agaccgtgca aacggatgta tccgtgattt ggaacatgct
     6481 tatagcaaag acggtggatt ggccgtattg aaaggcaata ttgcccaaga cggttgtgtg
     6541 gtaaaaacag caggtgtaga cgaaagtatc tggaaattta ccggacctgc caaagtattt
     6601 gattcgcaag aagcagcctg tgaaggcatc ctcggaggcc gagtcgtcag tggcgatgta
     6661 gtcgtcatta cgcacgaagg tccgaagggt ggtcccggta tgcaggaaat gctttatcct
     6721 acctcttata tcaaatctcg tcatctcgga aaagaatgtg ctttgattac cgacggacgt
     6781 ttcagtggtg gaacttccgg attgagtatc ggacatattt ctcctgaagc ggcagctgga
     6841 ggcaatatcg gaaaaattgt agacggagac attatcgaaa tcgatattcc ggcccggaag
     6901 attaacgtgc gactgacgga tgaagaactg gcggcccgtc cgatgactcc tgtcactcgt
     6961 gaccgttatg taccgaagag cctgaaggcg tatgccagca tggtaagctc tgccgataag
     7021 ggagcagtga gaattatata atatagttga taggtaatag ttagctgcgc agcacttagc
     7081 gcaatgattg taaaccattc attttcaact gtcatttctc aactatcatt tatcatttat
     7141 caactatcaa ctaatatgaa agatttaata acaggtgcag aggctttgat gcgctccttg
     7201 gaacatcagg gagtgactac catctttggt taccccggtg gttctattat gccggtattc
     7261 gatgccttgt acgatcatca aaatatattg aaccatatct tggttcgtca cgagcaggga
     7321 gccgcccatg ccgcacaagg ttatgcccgt gtatcgggtg atgtaggtgt ttgcctggtg
     7381 acgagcggtc ccggagcaac caatacggta acaggcattg cggatgcgat gatcgatagt
     7441 acgcctatcg tggtgattgc cggacaggta ggaacaggct ttcttgggac cgatgctttt
     7501 caggaagttg acttggtagg tattacccag ccaatcacta aatggagtta tcagattcgc
     7561 cgtgcggaag atgtagcctg ggcggtagca cgtgcgtttt acattgctcg tagtggtcgt
     7621 ccggggccgg tggtactgga ctttgccaaa aatgcgcaag tagagaaaac gaaatacgaa
     7681 ccgacgaaag tcgattttat ccgtagctat gttcctgttc ccgatatgga cgaggagact
     7741 gtacaggctg ctgccgaact gattaataac gctgaacgtc cgcttgtatt ggttggacaa
     7801 ggtgttgaac tgggaaatgc acagagcgaa ttgcgcgagt ttatcgaaaa agcggatatg
     7861 cctgcgggtt gtacgctgct cggactttcg gctttgccga cagaacatcc gttgaataaa
     7921 ggtatgttgg gtatgcacgg caatctggga ccgaatatca ataccaataa atgtgatgtg
     7981 ctgattgctg tcggtatgcg ttttgacgac cgtgtgaccg gtaatttggc tacttatgcc
     8041 aaacaggcaa aagtgattca ttttgatatc gatcctgcgg aagttaataa gaatgtaaag
     8101 gtagatgtag ctgtattggg agattgcaag gaaacactgg cttctgtgac gaagctcctg
     8161 aaaaagaaca ctcataccga atggattgat agcttcaaag aatatgagaa agtagaggag
     8221 gaaaaagtaa tccgtcctga acttcatcct gccacaaact cgttgagtat gggggaagtg
     8281 gtacgtgcgg taagtgacgc tactcaccat gaagctgttt tggtaacaga tgtaggtcaa
     8341 aatcagatga tatctgcacg ctactttaaa tatacgaaag aacgcagtat cattacttcc
     8401 ggagggcttg gaacaatggg cttcgggctt cccgcagcta tcggggcaac tttcggagca
     8461 ccggagcgta ccgtatgcgt atttatggga gatggcggac tgcaaatgaa tattcaggaa
     8521 ctgggtacga ttatggagca gaaggctccg gtgaagatta tctgcctgaa caataattac
     8581 ctcggaaacg tacgtcagtg gcaagctatg tttttcaacc gtcgctattc gtttaccccg
     8641 atgttgaatc cggattatat gaaagtggcc tcggcttatg atattccttc caagcgtgtt
     8701 ttcactcgtg aagaactgaa ggaagctatt gctgaaatgc tggcaacgga cggtccgttc
     8761 ctgctcgaag cttgcgtggt ggaagaaggt aatgttttgc cgatgactcc tccgggtggt
     8821 tcggtaaacc agatgttgct ggagtgctag gagaagttga gaatggagag ttgagagttc
     8881 gcatttaaaa aattagagtt atgagtgata aaacgttata tacaatcatt gttcattcgg
     8941 agaatatagc tggattgctg aatcaggtaa ctgctgtatt tacccgtcgg caaataaata
     9001 ttgagagtct gaatgtatct gcttcttcta ttaaaggtgt acataagtat acaataacag
     9061 cctggactga taaggacatc attgagaagg tagtgaaaca gatcgaaaag aagatcgacg
     9121 tgattcaggc acattatttc acagaggatg agatttattt ccacgagatt gcattatata
     9181 aggtgtctac tcctgctttt caggagaatc cggaagcatc caagctgatt cgtagataca
     9241 atgcacgtat agtggaagtc aatccggtat tttctattgt cgagaaaaat ggaatgagcg
     9301 aagatataac ttcgctctat ggtgaactga aggctttgaa ttgtgttttg cagtttgttc
     9361 gttcaggacg tgtagcgatt actaccagct gttttgaacg ggtgaatgag tttctcgatg
     9421 gacgggaagc tatgtataac caaagtaaaa accaataaga ataatgagtg aagaaaatag
     9481 aatagggact tatcagtttg tggcagaacc gttccatgtt gacttcaacg gacgtctgac
     9541 tatgggggta ctgggaaatc atctactgaa ttgtgcaggt tttcacgcca atgaccgtgg
     9601 ttttggtatt gcaacgctga atgaggacaa ttatacatgg gtgctttcac gtctggctat
     9661 tgagttggat gaaatgcctt atcagtatga gaatttctcg gttcagacgt gggtggaaaa
     9721 tgtctaccgt ttgtttacgg accgtaattt tgctattatt gataaggatg ggaagaagat
     9781 tggctacgca cgttccgtat gggcaatgat taatcttaat acccgcaagc ctgccgactt
     9841 gttgactttg catgggggaa gtatcgtaaa ctatgtctgt gatgagcctt gcccgattga
     9901 aaagccttca cgtatcaaag tgacaagcga tcagtcgata gctaccctga cggcaaagta
     9961 cagtgatata gatatcaatg gtcatgtaaa cagcatccgt tacatcgaac atatccttga
    10021 tttgttcccg attgaattgt ataagaccaa acgtatccgt cgttttgaaa tggcgtatgt
    10081 ggcggaaagc tattttggtg atgaactctc tttcttctgc gatgaagtga atgcaaacga
    10141 gtttcacgta gaagtgaaga agaatggcaa cgaagttgtt tgccgctcga aagtgatatt
    10201 tgaataaatg tgagaatata aaatcaatta ataacagatg gcgtaagtca tcaaaaacta
    10261 aaaacaaaaa gaaaatggca cagttgaatt ttggaggtac tactgaaact gtagtaatcc
    10321 gtgacgaatt tccattggaa aaagctcgtg aagtattgaa aaatgaaaca atcgctgtaa
//
