LOCUS       c00008_gnlPro..        13256 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MBBIHBAC_8.
ACCESSION   c00008_gnlPro..
VERSION     c00008_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 19:25:58
            Original ID  :: gnl|Prokka|MBBIHBAC_8
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 112486
            Orig. end    :: 125742
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13256
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[122486:125459]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12973
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..13256
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13256
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="2"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             231..938
                     /locus_tag="ctg8_83"
                     /transl_table=11
                     /translation="MKKFFLIAVLLNMLFDGYAQTTLKVMSFNIHAGADASLEQLASFI
                     KKQNPDVVALQEVDYYTTRSKGVDMLLELSYLTGMHGMFFPAIDAHGGKYGNAILSKYS
                     FDETQKKILPYTSGTEKRCAAIVKIVLDDGTSVCVVGTHLDMANLSNGLLQVGELTKIP
                     QTGELCVLAGDLNRRVGTEHINLLSTVWDLAVSNTFDHVAYYPQNRWVVKETKIFEEVL
                     SDHKAIMAVLEIK"
     CDS             987..2405
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_84"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 1.1e-26, bitscore:
                     86.7, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="GFO_IDH_MocA_C (E-value: 4.8e-10,
                     bitscore: 32.2, seeds: 24, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNRAEFLRIMGAGAAAAAMSNFTSVSQAMESLQQKKKQNNGLIEE
                     LSSTLESQEAVVDKPITAIVIGAGARGRTYASYSEHFSKSLKIVGVADINKERKLHLKN
                     KYNLSDEHCFNDWSEVFSIPKFADAVIIATPDNLHYHPCLKALEAGYDVLLEKPVAQSV
                     KECTDILKYAKKYNRIVGICHVLRYAPYFMAMKKVLDAGMIGDIVSIQHMECIRFHHMA
                     HSYVRGNWKSARETTPIVIAKSCHDMDMMRWLVNKPCKSLSSYGGLTLFKRENAPAGST
                     ERCLDCAVEAECPYSAKRIYLKDRRYLYVFDIPDNERNDKKYASLIMDKLRTTDYGRCV
                     FRCNNDQCDHFVTSMEFEGNITGAFSMEAFTATGGRLTCIMGTKGWLKGDMKKFEVTDF
                     LTNKHSVWNQDISSLPGYEGHAGGDFGIVKDFVLAVANQDASYLTSSIDLSIESHVMGF
                     EAEHSRVLKKRIEL"
     CDS             2506..3420
                     /locus_tag="ctg8_85"
                     /transl_table=11
                     /translation="MNIEMRLYCILLYVFILSGLHAQQAENREYRKNQTFIGNDSDIMV
                     VSHRADWRNAPENSLQGIQNCIDMGVDMVEIDLKKTKDGHLVLIHDRTVDRTMNGKGKV
                     EDYTLAELKAMQLKNGVGCKTRHQIPTLEEVMLLCKGKVMVNIDKGYDYFQEVYAVLEK
                     TGTIECCVIKAELPYEQVKAENGDVLDKVIFMPVVQLHKEGAEAVIDSYQTYMKPAAYE
                     LVFDNDSPEILNLIKKVRNTGSNLFINSLWPELCGGHDDDRAVELHQPDESWGWIIDQG
                     AKLIQTDRPALLLEYLRNKKLHD"
     CDS             3434..4789
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 152.1; E-value: 6.5e-47)"
                     /gene_kind="transport"
                     /locus_tag="ctg8_86"
                     /sec_met_domain="MFS_1 (E-value: 1e-46, bitscore: 152.1,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKQLINFYKVSSPRPCNGEALSSSDTRRLKFLKWSTFLSATFGY
                     GMYYVCRLSLNVVKKPIVDEGIFSETELGIIGSVLFFTYAIGKFTNGFFADRSNINRFM
                     TTGLLITALVNLCLGFTNSFILFAILWGISGWFQSMGAASCVVGLSRWFTDKERGSYYG
                     FWSASHNIGEALTFLIIASIVSVLGWRYGFFGAGIVGLIGALIVWKFFHDTPESMGFPS
                     VNVPKQKKEMSETETADFNKAQRQVLLMPAIWILALSSAFMYISRYAINSWGVFYLEAQ
                     KGYSTLDASFIISICPVCGIIGTMFSGVISDKLFGGRRNVPALIFGLMNVFALCLFLLV
                     PGAHFWIDVLAMVLFGLGIGVLICFLGGLMAVDIAPRNASGAALGVVGIASYIGAGLQD
                     VMSGILIEGQKTVQNGVDVYDFTYINWFWIGAALLSVLFALLVWNAKSKEVD"
     CDS             4916..5050
                     /locus_tag="ctg8_87"
                     /transl_table=11
                     /translation="MENSLNDELLCSLKDELREVTAQINVHSEKLMDLLDQKKESSVN"
     CDS             5059..5304
                     /locus_tag="ctg8_88"
                     /transl_table=11
                     /translation="MSHLTPVIIEYRGNPKQYVSVVLDAINLGRLTYDGVANCEQTFRA
                     LASVVDVISPKNGKTLSVETLVSYEKKKRAGEFEEK"
     CDS             5354..5716
                     /locus_tag="ctg8_89"
                     /transl_table=11
                     /translation="LQYGKPQRNLRTYGGYVEAFMETLTEKEQDKIQYGLLLLKTQERL
                     STKFVKFVQDGVFELRTEYNGNIYRVFFIFDDGNIVVLFNGFQKKSQKTPGSEIDKALK
                     IKEEYYADKQSSNSRL"
     CDS             5682..5984
                     /locus_tag="ctg8_90"
                     /transl_table=11
                     /translation="MQINNHQIVDYDAVLDAKFGAEGTPERAEAEEKAYAFYTGQIIED
                     ARKKAKITQAELARRIGSDRSYISRVESGQTEPKVSTFYRIMNALGCRIEFSMSL"
     CDS             6003..6134
                     /locus_tag="ctg8_91"
                     /transl_table=11
                     /translation="MVGNLKKITVFFKFPTVFLRKKKEKVRVGEGKFLTFVFFFRRK"
     CDS             complement(6223..8340)
                     /locus_tag="ctg8_92"
                     /transl_table=11
                     /translation="MEHFTIFQDFYRVIAEMTEEEIVSAISNGTYRETVEDVRRIFAEQ
                     GEKAANEKKIELPEITFSANYRGGRSNATLVKYLGYIVVDIDHQTQEALARILALAKKC
                     AHTRIAFISPKGMGLKIVVRVCRTDGTLPETIQEIEDFHHAAYHKIASFYAQLCGVEVD
                     TSGQDVSRTCLFSYDPDIYFNPDATAVIVEQPPMFFKSQKKKRASGKKKKTTAPDNNPL
                     TEQVALNYHSSHASLMVTLNYYHNKSEKYVTGNRNNYLHCLACMYNRYGVPQEEAAAFI
                     KSQFTDLPADEMDALIGSAYGHNEEFDTRKLNSTQKRILQIEQHIKENYDTRYNEVLHI
                     MEYRRRKTDTEQPEPFHILDEMMENSIWMEMNELGYSCTVKTIQNLIYSDFSSTYHPIR
                     EYLDSLPEWDGTDYIGILANSVHTSHQKFWVECLERYLVGMCAAATQDDVVNHTVLLLC
                     SEIQNIGKTTFINNLLPPELRAYLSTGLINPNNKDDLAKIAQAMLINLDEFEGMNGREL
                     NIFKDLVTRKVISIRLPYARRSQNFPHTASFAGTCNYQEVLHDTTGNRRFLCFHVDSME
                     FIKINYTQLYAQIKYLLNKPGYQYWFTQSENSRIEENNEDFIFHSPEEELVLTHIRKPE
                     RFEKVHYLTVTEIAELIRERTGYQYSHGTKAQLGKVMSKHGFEFHKGKNGRRYTVFIID
                     TEQVKSNRLYE"
     CDS             complement(8428..8658)
                     /locus_tag="ctg8_93"
                     /transl_table=11
                     /translation="MYYPDQPFHIRTYKKSELAHLYNPNVCLKVALQILRRWIVYNLPL
                     LQELEQEGYRARNRLLSPRQVATIIRYLGEP"
     CDS             8852..9355
                     /locus_tag="ctg8_94"
                     /transl_table=11
                     /translation="MAMTVTYSVVPRKNPAKKDESAKYYAQAQASGELDFEELCEGITS
                     RSTCTETDVRAAISGILYEAKRALKAGRIVRLGDLGSLQIGLNSEGAVSVKEFSSSLIT
                     AAHIIFRPGKTLADITKILSYQQVTTRAVAQTGGSGNEGEDDDKGSGGGSDGGGSGEAP
                     DPAA"
     CDS             9376..9543
                     /locus_tag="ctg8_95"
                     /transl_table=11
                     /translation="MKEIVTKILDVIMFLVPFFGKRKRNRIVREVRFNATHKEVCNVKT
                     TEREKDDEKD"
     CDS             9530..9973
                     /locus_tag="ctg8_96"
                     /transl_table=11
                     /translation="MRKISLIVIHCSATRVDRDFTAKDVDTAHRFRGFSCWGYHYYIRK
                     SGQIEPMRDEDTVGAHARGFNAISLGVCYEGGLDENGKAADTRTSRQKEAMHRLVSELL
                     QRYPDAKVVGHRDLSPDTNYNGIVDPWERIKECPCFEVKAETW"
     CDS             complement(10001..10729)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 74.2;
                     E-value: 4.3e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_97"
                     /sec_met_domain="Radical_SAM (E-value: 3.7e-29, bitscore:
                     94.9, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIAGKG
                     GTPTPPEEIVRMAMSQRPFFGKRGGVTFSGGEPTFQAKALVPLVRELKEKGIHVCIDSN
                     GGIWNEEVEELFKLTDLVLLDIKEFNPARHQALTGRSNEQTIRTAAWLEENEKPFWLRY
                     VLVPGYSDFEEDIRRLGEALGKYKMVQRVEILPYHTLGVHKYEAMEQEYKLKDVKENTP
                     EQLEKAAEVFKEYFTTVVVN"
     CDS             complement(10745..12973)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_98"
                     /sec_met_domain="Gly_radical (E-value: 4.2e-46, bitscore:
                     148.6, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1172.7, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKIFKDGLWSTEINVRDFVSHNITPYYGDASFLEGPTERTKA
                     VWNRCLEALAEERANNGVRSLDNVTVSTITSHKAGYIDKENELIVGLQTDELLKRAIKP
                     FGGINVVSKACHENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRMALYGIDRLIEAKKEDLRNLTGPMTEARIRLREEVAEQIKALKDMK
                     VMGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYMEYELSK
                     GTITESFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESLGGRLNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNLTVLWSPELPEGFKEFCAKVSIDTSSIQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARCNLAKALLLAINGGRCENTGTVMVKNIPVLTSDTL
                     NFEEVMSNYKKVLTEIARVYNEAMNIIHYMHDKYYYEKAQMALVDTNPRINLAYGVAGL
                     SIALDSLSAIKYAKVTARRNDIGLTEGFDIQGEFPCFGNDNDKVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGVAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATEEDRVENLVTMMDGYFTKGAHHLNVNVLN
                     REMLYDAMEHPEKYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
ORIGIN
        1 agttctgtct ttgatatatt ggataggaaa tatcgtaaga tatacaattc ggcggaaaat
       61 aattctctaa gttccaagac tgaatataat ttcatattgg ctcctttaaa acagaattgg
      121 actactcagc ttatacaaat agaaggagaa gaattgactt cagtttacaa ggctactttg
      181 gttaaaatga tattgaaata gaatgttaaa tggaattaga ttataataaa atgaaaaagt
      241 tttttttgat tgctgtatta ttgaatatgt tgtttgacgg ttatgcgcag acaaccttaa
      301 aagtcatgtc ttttaatata catgccgggg ctgatgcttc attggaacaa ttggcttctt
      361 ttataaaaaa acaaaatcca gatgttgtag cgttacaaga ggtagattac tatactactc
      421 gttctaaagg agttgatatg ttattggaat tatcatacct gactggtatg catgggatgt
      481 ttttcccagc aattgatgct catggtggaa agtatgggaa tgctatttta agcaaatata
      541 gttttgatga gacacaaaag aaaatattgc cttatacttc ggggacagaa aagcgttgtg
      601 ctgccattgt gaaaatagta ctagatgatg gtacttccgt gtgcgttgtc ggtacacatt
      661 tggatatggc gaatctttct aatggtttgt tgcaagtagg agaattgaca aagatacctc
      721 agacaggaga gttgtgtgtc ttggcaggtg acttgaacag aagagttggt acggaacata
      781 tcaacttact aagtactgta tgggatttag ccgtaagtaa cacttttgat catgtggctt
      841 attatcctca aaatagatgg gtggtgaaag aaactaaaat ttttgaagaa gtactttctg
      901 accataaagc tataatggca gttttagaaa tcaaataagg agtggaatac tttacttacc
      961 tcattaataa attgaaataa taaaaaatga atagagcaga atttttaaga ataatgggag
     1021 ctggtgcagc agctgccgcg atgagtaatt ttacatcagt atctcaagca atggaaagcc
     1081 tgcaacagaa aaaaaaacag aataatgggc ttatagagga actatcgtct actcttgaaa
     1141 gtcaagaagc agtagtagat aagccaataa cagcgattgt tattggtgct ggtgcccggg
     1201 ggcgcaccta tgcaagttat tcggagcatt tttcaaaatc actgaaaata gttggtgtgg
     1261 cagatataaa taaagaacga aaactacact tgaaaaataa atataattta tcagatgaac
     1321 attgttttaa tgattggtct gaagtattca gtattcctaa attcgcggat gccgtcatta
     1381 ttgctactcc ggataattta cactatcatc cttgtttgaa ggcattggaa gctggttatg
     1441 atgttttact ggagaaaccg gtcgctcaat ctgtaaaaga atgtacggat attctgaagt
     1501 atgccaagaa atataatcgc attgtgggga tatgccatgt gttgcgctat gctccctatt
     1561 ttatggcgat gaagaaagtt ttggacgcag gtatgattgg cgatattgtc agtattcaac
     1621 atatggaatg tattcgcttc catcatatgg ctcactcata tgttcgcggt aattggaaga
     1681 gtgctcggga aactactcct attgttatag caaaatcgtg tcatgacatg gatatgatgc
     1741 gttggttagt caacaaaccg tgcaagtctc ttagttctta tggtggctta actttgttta
     1801 agcgcgaaaa tgccccggct ggatctacgg aacgttgcct tgattgtgct gtggaggcag
     1861 aatgtcctta ctcggctaaa cgtatttatt tgaaagatag acgttatctt tatgtgtttg
     1921 atattccgga taatgaacgg aatgataaaa aatatgcttc gttgattatg gacaaattaa
     1981 gaactacaga ttatggacgt tgcgttttta gatgcaataa tgatcagtgc gatcattttg
     2041 ttacttcaat ggagtttgaa ggaaacatta ctggtgcttt ttctatggag gcatttacgg
     2101 caactggcgg tcgattgact tgtattatgg gcactaaagg atggctgaaa ggagatatga
     2161 agaagtttga ggtgacggat ttcttaacca ataaacattc tgtctggaat caggatatat
     2221 catctttgcc cggatatgag gggcatgcag gtggtgactt tggcattgtc aaagattttg
     2281 ttttagcagt ggctaaccaa gatgcttctt atctgaccag ctcaattgat ctttctattg
     2341 aaagccatgt gatgggattt gaggctgaac atagtcgggt acttaaaaag aggattgagc
     2401 tataatgacc gtatattctc caccggatat atatatggtg gagaattaaa atatcagaca
     2461 ttttggggag ataggaaaag agaaggaaga acgataaaat aatgaatgaa tattgaaatg
     2521 agattatatt gtattttatt atatgtattt atattatctg gattgcatgc tcaacaggca
     2581 gaaaataggg aatatcgaaa aaatcaaacc tttataggga atgatagtga tattatggtt
     2641 gtatctcacc gtgccgattg gcgtaatgca ccagagaatt cattacaagg tatacaaaac
     2701 tgtattgata tgggagttga catggtggaa atagatttaa aaaaaacgaa agatggacat
     2761 ttggtgttga ttcatgacag aacggtagat cgtacaatga atggaaaagg gaaagtggaa
     2821 gattatacct tggcggaatt gaaagcaatg cagttgaaaa atggggtagg ttgtaaaacg
     2881 agacaccaaa ttcctacatt agaagaagtc atgctgctgt gtaaagggaa agttatggta
     2941 aatattgata aaggatatga ttattttcag gaagtttatg ctgttcttga gaaaacagga
     3001 acaatagaat gttgtgtaat taaagccgaa cttccttacg aacaagttaa agcagaaaat
     3061 ggtgatgtgt tagataaagt aatttttatg cctgttgtgc agcttcataa agaaggagcg
     3121 gaagctgtca ttgatagtta tcagacatac atgaaacctg ctgcctatga actggttttt
     3181 gataatgaca gtccggagat tcttaatttg ataaagaaag tacgtaatac aggctctaat
     3241 ctttttataa attcgctttg gcctgaacta tgtggcggcc atgatgacga ccgtgcagta
     3301 gaacttcatc agccggatga aagttggggc tggattattg accagggagc caagctaatt
     3361 caaacagatc gtcctgcttt attattggag tatttgcgta acaagaaact tcacgattaa
     3421 acgcacttcc ttcatgttga aacaactaat caatttttac aaggtctctt caccgagacc
     3481 ttgtaacgga gaagctttgt cttcatccga tacccgtcgt ctgaagtttc tgaaatggtc
     3541 tactttcctt tctgcgactt ttggttacgg tatgtattat gtgtgccgtc ttagtctgaa
     3601 tgtcgtaaag aaacctattg tagatgaagg aattttttcg gaaacagagt taggcatcat
     3661 aggttccgta ttgttcttca cctatgccat cggaaaattc acgaacggtt tctttgccga
     3721 ccgtagtaat atcaaccgtt ttatgactac cggtttattg ataactgctt tggttaacct
     3781 ctgtctcggt tttactaatt cttttatcct gttcgctatc ctttggggga ttagcggctg
     3841 gtttcaatct atgggagcag cctcttgtgt agtagggctt tctcgttggt tcacggacaa
     3901 agagcgcggt tcatactatg gcttttggtc tgcgagccat aatatcggcg aagcgttgac
     3961 ttttctgata atagcctcaa ttgtcagtgt gttgggctgg cggtatggtt tcttcggagc
     4021 cggtatagtg ggattgatag gagcgttgat cgtctggaag ttcttccatg atactcccga
     4081 aagcatggga tttccttcgg tgaatgttcc caaacagaaa aaggaaatga gtgagacaga
     4141 aacggctgat tttaataaag cacagcgtca ggtattgctg atgcctgcca tttggatact
     4201 ggctctttcg agtgctttta tgtatatcag tcgttatgct atcaatagtt ggggcgtttt
     4261 ttatttggaa gctcaaaagg gttactccac cttggatgcc agttttatca tttctatttg
     4321 tccggtctgt ggcataatcg gtactatgtt ttcaggtgtt atttctgata agttatttgg
     4381 tggacgtcgc aatgttcctg cgttaatttt cgggttgatg aatgtatttg ctctctgtct
     4441 gtttctctta gttccgggag ctcatttttg gatagacgtg ttggcaatgg ttcttttcgg
     4501 tttaggtatc ggagttttga tctgttttct gggtggtttg atggcagtgg atattgctcc
     4561 ccgtaatgct tcgggtgctg cattgggagt agtcggtatt gccagctaca tcggagccgg
     4621 attgcaggat gtgatgagcg gtatattaat agaagggcaa aagactgttc agaatggcgt
     4681 tgatgtttat gacttcacgt atatcaattg gttttggatt ggtgctgctt tgctttcggt
     4741 gttgtttgct ttgctggtat ggaatgcaaa atcaaaagaa gtggattaaa gtgagtacat
     4801 taggttagaa tataagtctt tgttttcgag gtattagaca ccattccggg aagtaagtaa
     4861 tgattgctta tctttctgga atggcttttt tataatcaat taaatagaaa gttttatgga
     4921 aaattcattg aatgatgaat tattgtgttc attgaaagat gaacttcgtg aagtaactgc
     4981 acaaatcaat gtgcatagtg aaaaattaat ggatctgctc gaccaaaaaa aagaatcgtc
     5041 ggtcaactga ctcgagagat gtcgcatctc acgcctgtca tcatcgagta tcggggaaat
     5101 ccgaagcaat atgtctctgt tgtgctcgat gccatcaatc tgggtaggtt gacgtatgac
     5161 ggagtagcaa attgcgaaca gacttttcgt gcgttagcaa gcgttgtaga tgtgataagc
     5221 cctaagaatg ggaaaacgct tagtgtagag acgctggtgt cttatgagaa gaaaaagcgt
     5281 gctggagaat ttgaggaaaa ataatataaa ataaaaagac gattgttgta tagttgaaca
     5341 acaattcgca tatttgcagt atggaaagcc tcaacgtaac ctccgtacat acggaggtta
     5401 cgttgaggct ttcatggaga ctttaaccga aaaggaacaa gataaaatcc agtatggact
     5461 actcttgttg aaaacacaag aaagactctc cactaaattt gtaaaatttg ttcaggacgg
     5521 agtttttgaa cttcgtacag aatataatgg taatatatac cgggtatttt tcatatttga
     5581 tgatggaaat attgtagtgt tgtttaatgg ctttcaaaag aagtcgcaaa aaacaccggg
     5641 tagtgaaata gataaagcat taaaaataaa ggaggaatat tatgcagata aacaatcatc
     5701 aaatagtaga ttatgacgct gttcttgatg cgaaatttgg agcagaaggt actcccgaac
     5761 gtgcggaagc agaagaaaaa gcgtatgctt tctataccgg gcaaattatc gaagacgcaa
     5821 ggaaaaaggc taagattact caagcagaat tagcccggcg tatcggttcc gaccgttctt
     5881 atatttcaag agtggaaagt ggtcagacag aacctaaggt ttctaccttc tatcgcatca
     5941 tgaatgcgtt aggttgtagg atcgaatttt cgatgtcttt ataaaaagcg attaaaaaaa
     6001 acatggtggg aaatttgaaa aagataactg tctttttcaa atttcccacc gtttttttga
     6061 ggaagaaaaa ggaaaaggtg agggtaggtg agggtaaatt tctaacattc gtattttttt
     6121 ttagaagaaa atagaagaat agaaataaga aatataaaaa tgaaaagttg caaaagtacc
     6181 ctcaccaacc ctcacctttt tgcgtgcgaa ggagatgaaa tcttattcat atagcctgtt
     6241 tgatttcacc tgttccgtat caataatgaa tacagtgtat cttctcccgt tttttccctt
     6301 atgaaattcg aagccgtgtt tggacatcac ttttcctagt tgggctttgg ttccgtgaga
     6361 atattgatac cccgtccgtt cgcgaatcaa ttccgcaatt tcagtgaccg tcagataatg
     6421 caccttttcg aaacgttccg gtttgcggat atgtgtcaac accagttctt cttccggtga
     6481 gtggaaaatg aaatcctcgt tgttctcttc aatccgtgag ttttccgact gggtgaacca
     6541 atactgatac cccggcttgt tgagtagata cttgatttgt gcatacaatt gcgtgtagtt
     6601 tattttgata aactccatcg agtcgacatg aaagcagaga aaacggcggt tacctgtggt
     6661 gtcgtgaagc acttcctggt aattgcatgt gccggcaaaa gaagccgtgt gagggaagtt
     6721 ctgtgaacgc cgcgcgtatg gcaggcggat gctgattact ttgcgggtaa ccaaatcctt
     6781 gaagatattc agttcccgtc cgttcatccc ttcaaactca tccagattga taagcatcgc
     6841 ctgcgctatt ttggccagat catccttgtt gttcgggttg ataagaccgg tagaaagata
     6901 ggcgcgcaat tcgggcggca gcaggttgtt gataaacgta gtctttccga tgttctgtat
     6961 ttcgctgcaa agcaacaaaa cagtgtggtt caccacatcg tcttgtgtgg cggcagcgca
     7021 cattcccacc agataacgtt ccagacattc tacccaaaat ttctggtgac tagtatgcac
     7081 gctgttggca aggataccga tataatccgt tccgtcccat tcaggcagcg agtctaaata
     7141 ttcgcgaata ggatggtaag tgctgctgaa gtcggagtag atcagatttt gaattgtttt
     7201 gacggtgcac gaatagccta gttcgttcat ctccatccaa atgctgtttt ccatcatttc
     7261 gtcgagaata tggaaaggtt ccggttgctc cgtgtccgtt ttccttctgc gatattccat
     7321 gatatgaagc acttcgttgt agcgtgtatc gtaattttct ttgatatgtt gctcaatctg
     7381 taatattcgc ttctgcgtac tattcagctt gcgggtgtcg aattcctcat tgtgtccgta
     7441 agcactcccg atcagtgcgt ccatttcatc cgcgggaaga tcggtgaact ggctcttgat
     7501 aaaagctgcc gcctcttcct gggggacacc gtagcgattg tacatacaag ccaggcaatg
     7561 caggtagttg ttccggttgc cggtgacgta cttttcggat ttattgtgat aatagttcag
     7621 agtcaccatt aaggaagcgt gcgaggaatg gtagttgagt gccacttgtt cggtgagggg
     7681 attgttgtct ggtgctgtcg tctttttctt tttgccggat gcccttttct tcttttgaga
     7741 cttgaagaac atcggtggct gttccacgat gacagctgtg gcatcgggat tgaaataaat
     7801 atccggatcg taagagaaca ggcaagtgcg gctgacatcc tgtccggaag tgtcgacctc
     7861 aactccgcag agctgggcat aaaaggaagc gattttgtga taagcggcat gatggaaatc
     7921 ttcaatttcc tgaatcgttt cgggcaatgt cccgtccgtc cggcatacac gtaccacgat
     7981 tttcagtccc attcctttgg gactgatgaa agcgatgcgg gtgtgggcac acttttttgc
     8041 cagtgcgagg atgcgtgcca atgcttcctg tgtctgatgg tcgatgtcta ccacgatgta
     8101 tcccagatac ttgacgagag ttgcgtttga acgtcctccc cggtagttgg ctgaaaaggt
     8161 gatttccggt agttctattt tcttttcgtt tgctgctttc tcgccttgtt ccgcgaagat
     8221 tcggcgcacg tcctccactg tttcccggta tgtgccgttg ctgatggccg atacgatttc
     8281 ttcttctgtc atttcggcta tgacgcggta aaagtcttga aagatggtaa aatgctccat
     8341 gttggtttgt tctttttaat ttgcggttgc aaagaaattt gtttgtaaaa taatagaatg
     8401 gaacttttcg tttttttgat taagttccta gggttctccc aaatagcgta tgatcgttgc
     8461 cacttgccgg ggagagagaa ggcggttgcg ggcacgatag ccttcttgtt cgagttcttg
     8521 caggagcgga aggttgtaga caatccaacg acgtagtatt tgtaaggcta ctttgaggca
     8581 tacgttgggg ttgtaaagat gagctagttc cgacttttta taagtgcgga tatgaaacgg
     8641 ctgatccgga taatacatga tgaatgatgt ttggtttatg ctataaagtt actgaaaatt
     8701 aatggtttat taaaagaata acgtcattat tattcataga atatcaggaa acttcgttgg
     8761 ggaatccgga gggtgaaaaa tgtgttatct ttatgtcgtt aacaaataag gaacgcgttc
     8821 gaaatgtatg aaaatttaaa attattttat tatggcaatg acagtaactt attcagtagt
     8881 gccgcgcaag aatcctgcca aaaaggatga gtcggcaaag tattacgcgc aggcacaggc
     8941 ttcgggagag ttggattttg aagagttgtg cgagggaatc accagtcggt ctacctgtac
     9001 ggagacagat gtgcgtgccg ccatttcggg tattctttat gaggcgaagc gtgcgttgaa
     9061 agcgggaaga atagtccggc tgggtgattt gggcagtttg cagatcgggt tgaacagtga
     9121 aggagctgtg tcggtcaagg agttttcaag ttcgctgatt acggctgccc atattatttt
     9181 ccgtcccgga aagacgttgg cggacatcac gaagattctt agctaccagc aagtaacgac
     9241 gcgtgcagtg gcccaaacgg gcggtagcgg caatgaagga gaggacgatg acaaaggttc
     9301 cggtggcggt tcagacggtg gtggaagcgg agaagctccg gatccggcag catgataact
     9361 ttaatattgg atcaaatgaa agaaattgta actaagattt tggatgtaat catgttcctt
     9421 gtgcctttct tcggaaaaag aaagcggaac agaattgtga gagaggtgcg cttcaatgct
     9481 acccataagg aagtgtgtaa tgtgaaaacg acggaaaggg agaaggacga tgagaaagat
     9541 tagtctgatt gtgattcact gctctgctac ccgtgtcgat cgcgacttca cggcgaagga
     9601 tgtggacact gcccatcgct ttcggggctt ttcgtgttgg gggtatcatt attatatccg
     9661 caagtcggga cagatagaac cgatgaggga tgaagatacg gtgggtgctc atgcacgcgg
     9721 ttttaatgcg attagtttag gggtgtgcta tgaaggcggg ctggatgaga acggaaaggc
     9781 agcggataca cgtacttccc gccagaaaga ggcgatgcat cgtctggtaa gcgagttgtt
     9841 gcagcgttat ccggatgcaa aggtggtcgg tcaccgggac ttgagccctg acactaatta
     9901 taatggaatt gtagacccct gggaacggat caaagagtgt ccctgttttg aggtgaaagc
     9961 agagacatgg tgatttttat cctatttatt actgtggtgg ttaattgacc accacagtag
    10021 tgaaatactc tttaaatacc tccgcggctt tttcaagttg ttcgggggta ttttctttta
    10081 cgtctttcag cttgtattcc tgctccatcg cttcatactt atgtacgcct aatgtatgat
    10141 aaggcaggat ttccactcgt tgcaccatct tatattttcc cagagcctct cctaaacggc
    10201 ggatgtcttc ctcgaaatcg ctgtatccgg gcactaatac ataacgcagc cagaaaggtt
    10261 tctcgttttc ttccagccat gctgccgtgc ggatggtttg ctcgttactt cttccggtca
    10321 gtgcctgatg gcgtgccgga ttgaactctt taatatccag caatacaaga tccgtcagtt
    10381 tgaaaagttc ttctacttct tcgttccaga taccaccgtt gctgtctatg catacatgta
    10441 ttcccttttc tttcagttca cgcactaaag ggactagtgc tttggcctga aacgtaggtt
    10501 ctcctccgga gaaagtgact cctccgcgtt tcccgaaaaa aggacgttgg ctcatagcca
    10561 tgcggacgat ttcttccggt ggagtaggtg tgcctccttt tccggctatc gtgtcgggat
    10621 tggcacaata caggcagcgg aaattgcatc cttgaagaaa aacgacgagc cgtaagcccg
    10681 gcccgtcgaa tgttcccata ctttcgtatg aatgtacgtt tatcgtcata ttgagtagat
    10741 ctgattacat acgttcgtgg aagctacggc tgattacttc caattgatgt tcgcggctca
    10801 acttcacgaa gtttacggca taaccggaaa cacggattgt aagctgcgga tatttttccg
    10861 gatgctccat tgcgtcgtaa agcatttcac ggttcagcac atttacgttc aagtggtgag
    10921 cgcctttggt gaagtaacca tccatcattg tcaccagatt ttctacgcga tcctcttcag
    10981 tagctcccag tgatttcgga acgatggaga aggtgttgct gataccgtct tgtgagtcgc
    11041 ggtaacgtaa tttcgctacg gaactcaaag aggcgatagc accgttcttg tcacgtccgt
    11101 gcatcgggtt ggctcccgga gcaaaagcga cacctttggc gcgtccgtcg ggagtagcac
    11161 ctgttttctt gccatacatc acgttggaag tgatggtgag caaagacaga gtaggacggg
    11221 catttttgta aaccggaagt ttcttcaatt cttcgctgaa gaaatagact aggtcaacac
    11281 ccaggtggtc taccttgtcg ttgtcattac cgaagcaagg gaattcgcct tgaatatcga
    11341 aaccttctgt cagaccgatg tcattgcggc gtgcagtcac tttggcatat ttgatggccg
    11401 acagtgaatc gagggcgata gaaagtccgg ctacaccgta agcaaggttg atgcgcgggt
    11461 tggtatctac aagagccatt tgggcttttt cgtagtaata cttatcatgc atataatgga
    11521 tgatgttcat cgcttcgttg taaacacggg cgatttctgt caataccttc ttgtagttgc
    11581 tcattacttc ttcgaagttc agtgtgtcgc tggttagtac ggggatattt ttcaccatta
    11641 ccgtaccggt gttttcgcaa cgtccgccgt tgatggcaag cagcagggct tttgccaggt
    11701 tgcaacgtgc gccgaagaat tggatttgtt ttccgatttc ctgataagat acgcagcacg
    11761 cgattccgta gtcgtcagac tggcgcactt cacgcatcag gtcgtcgttt tcatattgga
    11821 tggaagaagt gtcgatagat acttttgcgc agaattcttt gaatccttcc ggcagttccg
    11881 ggctccacaa tacagtcagg ttcggttccg gtgaagggcc gaggttgtag agtgtttgca
    11941 ggaagcggaa agaagtcttt gtcaccttgg tacgtccgtc gttgaggcgt ccgcccagag
    12001 attcggttac ccatgtcggg tcgccggcaa agatgtcgtt gtaagattgc atacgcaggt
    12061 gacgcaccat acgcagtttg atgacaaact ggtcgatcag ctcctgtgcg aaagattctg
    12121 tgatggttcc tttgctcaat tcatattcca tataaatgtc gaggaacgaa gagacgttac
    12181 ccagtgacat ggcagcaccg tcttgttctt ttacggcagc aaggtaagcc atgtacaccc
    12241 attgtactgc ttcttgtgcg gtgtaggcag gacggctcaa gtcgagtccg tagtattcgc
    12301 ccattacctt catgtccttc aatgccttga tttgctctgc cacttcttcg cgcaggcgga
    12361 tgcgggcttc ggtcatcgga ccggtaaggt tacgcaaatc ttcttttttt gcctcaatca
    12421 gtcggtcgat accatagaga gccatacggc ggtagtcgcc gatgatacgt ccgcgggcat
    12481 agttgtcagg aagtccggtg aggaatccca gagaacggaa cgaacggatt tcttcggtat
    12541 atacgtcaaa tactccgtca ttgtgcgtct tgcggtagtg agtgaatata tcttttacac
    12601 ggtcgtccac ttccacgccg ttttcatggc aggctttgct caccacgttg atacctccga
    12661 aaggtttgat tgcacgtttc agaagttcgt ctgtttgcag accgacgatc agttcgtttt
    12721 ctttgtcgat atatccggct ttatgagaag tgatggttga gacggtgaca ttatccagtg
    12781 agcgtactcc gttattggct ctttcttctg ccagtgcttc gaggcagcgg ttccatacag
    12841 ctttagtgcg ttcggtaggt ccttcgagga aagaagcatc tccataatac ggagtgatgt
    12901 tgtgactaac gaaatctctt acgttgattt ctgtgctcca aagaccgtct ttaaagatct
    12961 tatttaattc cataaatgat aaaattagag gttgtagtta tccttttctt tagagcgcac
    13021 aaagttacaa cgttttttca tataatcagc ataaatatgc tgtattttat gcttttcaac
    13081 ataaaatacc tagatattgc tattctttgg aaatgatgtt cgtgattttt ttttgtgaaa
    13141 actcttgtaa gtttaaaata tattcgtacc tttgcaccgc ttttaacgaa aagcacttct
    13201 gaaaaggaag ttttggagag gtggcagagt ggtcgattgc ggcggtcttg aaaacc
//
