LOCUS       gnlProkkaJPGIKCND_86   10046 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JPGIKCND_86.
ACCESSION   gnlProkkaJPGIKCND_86
VERSION     gnlProkkaJPGIKCND_86
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-02 07:27:03
            Original ID  :: gnl|Prokka|JPGIKCND_86
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10046
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10046
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[6760:8349]"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      6761..8349
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     cand_cluster    1..10046
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10046
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /tool="antismash"
     CDS             complement(3..101)
                     /locus_tag="ctg86_1"
                     /transl_table=11
                     /translation="MQIITLIAALPGAVAQGLIWGIMAIGVYLTFRI"
     CDS             complement(252..1238)
                     /locus_tag="ctg86_2"
                     /transl_table=11
                     /translation="MKRKALAITLAAAMAMGTCAVTASAADGDKYTIGICQLVQHEALD
                     AATQGFKDEVTKELGEDAVTFDEQNAQGDSNTCSTIINSFVSNNVDLILANATPALQAA
                     AAGTSDIPILGTSVTEYGVALGLDDFNGTVGENISGTADLAPLDQQAAMLNELFPDAKN
                     VGLLYCSAEANSQYQVDTVKAELEKLGYTCEYYAFSDSNDLSSVATTATDASDVIYVPT
                     DNTVASNTEIINNICLPAKVPVITGEEGICSGCGVATLSISYYDLGVTTGKMAVKILKD
                     GEDISTMPIEYAPNFTKEYNKDICEELGIEVPDDYVAIGEAAEETAK"
     CDS             1502..2266
                     /locus_tag="ctg86_3"
                     /transl_table=11
                     /translation="MAYSIMLDAGHGGQDPGAVYKGRQEKNDNLKLALAVGEILKNKGI
                     DISYTRTGDVYQTPFEKAQLANQAGVDYFISFHRNSSPKENQYNGAEVLIYDKSGIKYQ
                     MAENILGALGEVGFREIGVKERPGLVVLRRTRMPALLIETGFINSEEDNKLFDNKFSDI
                     AQGIADAILGSLDEETVQEPLYYRVQTGAFRKKENADRMLYQLLEKGYPSFMLHENGLY
                     KVQTGAYQQIGNAVNMEQRLRDDGYSTVIVTK"
     CDS             2545..3147
                     /locus_tag="ctg86_4"
                     /transl_table=11
                     /translation="MMNDVYEKFLKSSEEFIFAENKPEKSDIIFVPGNGYPQMAEKAAE
                     LFKKGMADWVLPSGKYSVVNGKFSGVLEKSNVYNKEYGTEWEFLRDVLIKNGVPDQKIL
                     KEDQATFTYENAIYSRQVTDHAELEIERAILCCKSYHARRCLMYYQLLYPKTEFYVVPV
                     NADGITRENWRKNEEGIDAVTGELSRIVKQFSLMLER"
     CDS             complement(3151..4434)
                     /gene_functions="other (smcogs) SMCOG1273:hypothetical
                     protein (Score: 354.6; E-value: 1.3e-107)"
                     /gene_kind="other"
                     /locus_tag="ctg86_5"
                     /transl_table=11
                     /translation="MDSSIAFQTVAILILIALSSFFSSAETAMTTVNKIRIQSLAEQGN
                     KRAVILEKIISDSPKMLSTVLIGNNIVNMSVSSLMTTLTIKILGNAYVGITTGILTLLI
                     LIFGEITPKNLATIHAEKLSLAYSRIIYGLMILLTPVVFIVNKITEGVLVILHVNPDEK
                     ANAMTEHELRTLVNVGEKDGVIENEEKQMIYNVFDFGDSTAKDVMIPRIDMTFIDINFS
                     YDELMAVFSEDMHTRFPVYEDNTDNVIGIINMKDLLVYPKDKPFSIRNILREPYFTYEY
                     KATADLMIEMRKASVNLAIVLDEYGATAGLVTLEDLLEEIVGEIRDEYDEDEVEDIKEI
                     QPEREYVVQGSAKLDDINEALHINLESEDYDSIGGYIIEQLDCLPKEGQSVTLESGIRL
                     VVDRLDKNRIELVHIWLPEKKTETEEQP"
     CDS             4779..6287
                     /locus_tag="ctg86_6"
                     /transl_table=11
                     /translation="MSNNINRIRKNKLKGTGIFAAAALTAALIAGNNIPGVTRQVSAAE
                     SQENTVSSLIPDNITLDKPVELADVELPATEYGTFEWADGSFVPAQRVQSCEVLLIPAE
                     GQDLSHVDGWDPESGAVVGYINVIVNSITDSDNVDKTEGSGKTDPTENADPTETPETSS
                     EKPAADENADTDNKEDKESKSDQDNKTDTDNEENKIEEDKTDNKNNKDNNSNADKTDKD
                     TETTGKLEPADDMTQDKEDTKKDDEDGADDNIFDNPVLPDDKDDRPTDAEDSLSDEEKE
                     ERAALNHTCDGITVSGVNLPWYVQFRVSSGDSYQFTNESDAMIFQSYEFELWDLKNNTE
                     YEIPNGDYISVTVPVKSGYQYTIEHLLDNGATETIIPSVENGIMVFSTHSFSPFGIAGS
                     RQLVGPDAGNDTDDTDAVTPAPASSDSQSPDSGKNNTVSMNDSSDSNNGSSSDQNDNLT
                     ENKAVKNNNTVNTGDTTSIMPFVILFVAAAVIAGVAVFIKKRKK"
     CDS             6337..6687
                     /locus_tag="ctg86_7"
                     /transl_table=11
                     /translation="MKVRAILKSLLFAYALTGVALLLLALVLFAFDLGETAVDAGIIII
                     YVLACFMGGFMAGKIVRKDKYLWGVITGLAYYVLLLTVSVMAKGGWDMSAAHAVTTFFM
                     CTGGGTLGGMLS"
     CDS             6761..6901
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR03973"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SCIFF"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg86_8"
                     /sec_met_domain="TIGR03973 (E-value: 2.4e-28, bitscore:
                     87.3, seeds: 29, tool: rule-based-clusters)"
                     /sec_met_domain="SCIFF (E-value: 3e-28, bitscore: 87.0,
                     seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEHIKTLNTKNLQNTVKKGGCGECQTSCQSACKTSCTVGNQSCEQ
                     K"
     CDS             6982..8349
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Ranthipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg86_9"
                     /sec_met_domain="Ranthipeptide_rSAM_RRE (E-value: 1.2e-29,
                     bitscore: 91.9, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 7.8e-17, bitscore: 51.3,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 6.8e-15, bitscore: 45.3,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 1.8e-20, bitscore:
                     62.7, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLIHRYKSNGFNIVLDINSGCIHLVDEVTYEVLPYLEEGLGAEA
                     IAEKLENKYNREDIETSVRECNKLKEDGMLFTKDVYENVIEEFSNNRQTVVKALCLHIA
                     HDCNLACRYCFAEEGEYHGRRALMSYEVGKKALDFLIANSGSRKNLEVDFFGGEPLMNW
                     QVVKDLVKYGREQEKLHNKKFRFTLTTNGVLLNDEVMEFCNKEMGNVVLSVDGRKEVHD
                     YMRPFRKGAGSYDLIMPKFQKFAESRNQDKYYVRGTFTHHNLDFSKDVLHLADLGFKQI
                     SVEPVVAADTEEYAIREEDIPQIMEEYDTLAKEMIKREKEGKGFNFFHFMIDLTGGPCV
                     YKRLSGCGSGTEYLAVTPWGDFYPCHQFVGEEQYLMGNVDEGITKPEIQKEFGGCNVYT
                     KKDCKDCFARFYCSGGCAANAFHFHGDIKGNYEIGCELQRKRVECAIMIKAALACD"
     CDS             8461..10044
                     /locus_tag="ctg86_10"
                     /transl_table=11
                     /translation="MKKSKGIVVLLLTLILTVFFCFTAAVGIGPTGTGAAKHINTGLDL
                     AGGVSITYQAKESNPTSEEMSDTIYKLQKRVEQYSTEAQVYQEGSDRITVEIPGVTDAD
                     TILNDLGKPGSLYFITKEDADGNQNFTTGQDGYVLSRTMDEIKESGSVVLEGSDVADAQ
                     GGAIQNQNTSAKEYVVSLTLTSDGENSGKTKFAEATKNNVGKQIAIVYDNNIISAPNVN
                     EEISGGKAQISGMSDLEEAQNLASYIRIGSLGLELEELRSSVVAAQLGEEAISTSVLAG
                     AIGLIIVIIFMIIAYRIPGIVAGIALILYTSLMLITLNAFDITLTLPGIAGIILGIGMA
                     VDANVIIYARIREEIGAGVSVRNSIKSGFSKAFSAIFDGNITTLIAAFVLMWLGSGTVK
                     GFAYTLALGIVISMFTALVVSRLIVNALYAVGVRDPKFYGSAKERKAVDFLGKKKVFFA
                     ISIILILCGPAAMFANSHAGNKALNYSLEFSGGTSTTVTFNEDMDIKTIDSKVTPVVEE
                     VTGDKNVQPTK"
ORIGIN
        1 ataatgcgga atgtcagata aacaccgatt gccatgattc cccagatcag accttgtgcc
       61 acagcgcccg gaagcgcagc tattaacgtt ataatttgca tttgtaattt cctcctgttg
      121 agatgcgaaa agcgagagag gcgtcaaacc tttcccgctg atcgcatata aattgaattt
      181 tttataactg tttgataagc tgttatttaa aatcctgttg gtgtgagtat ttttcaactg
      241 tctgaccgga tttatttggc agtttcttca gcagcctcgc cgattgcaac ataatcgtcc
      301 ggaacttcga tgcccagctc ttcgcagata tctttgttat attcttttgt gaagtttggt
      361 gcatattcga tcggcattgt ggaaatatct tcaccgtcct ttaaaatctt aacagccatc
      421 ttaccggttg taacaccaag gtcataatag ctgatggaaa gtgtcgcaac accgcatccg
      481 ctgcagatac cttcttcgcc tgtgattacc ggaacttttg ccggaaggca gatgttgttg
      541 atgatctctg tgttggaagc aactgtatta tctgtcggta cataaattac atcacttgcg
      601 tcagttgctg ttgtagcaac agaagagaga tcattagagt cagagaatgc ataatattca
      661 catgtatatc cgagtttttc aagttcagct tttactgtat ctacctgata ctgagagttt
      721 gcttcggcag aacagtagag aagacctaca ttttttgcat ccgggaaaag ttcattgagc
      781 attgctgcct gttgatcaag gggagcaagg tctgcagttc cggaaatatt ttcgcccaca
      841 gtcccgttga aatcatccag tccaagtgca acaccgtatt cagtaacaga agtaccaaga
      901 atcggaatat cgcttgtccc tgctgcagct gcctgaagag caggagttgc atttgcaaga
      961 atcaggtcaa cattattgga aacgaagctg ttaatgattg tagaacaggt gttggaatct
     1021 ccctgtgcgt tctgctcgtc aaaggtaact gcgtcttctc ccagttcttt ggtgacttca
     1081 tccttgaatc cctgtgtcgc agcgtcgaga gcttcgtgct gtacaagctg acagataccg
     1141 attgtatatt tgtctccgtc agcagcactt gctgttactg cgcaggttcc catagccatg
     1201 gctgctgcaa gagtgattgc taatgctttt cttttcataa tgatatatcc tcctaatata
     1261 atgtttaaat taagtcaggt aagaattgcg tttattattt gataatataa aacttacctg
     1321 aatccgaatg attttctgca gggaaagcag tactggtaaa tgattcggat aatgtcatcg
     1381 ggctattcga ctatgacgtt ttaaagtata acgctttagt gtgaaaaagt caagcgacct
     1441 gcacaattat atttttaatt catatagtat aaagagtata tgaagaaagc agagtgtcgt
     1501 catggcatat tcgatcatgc tggatgccgg acatggaggt caggatccgg gagccgtata
     1561 taagggaaga caggaaaaga atgacaatct taaacttgct cttgcggtag gtgagatttt
     1621 aaaaaataaa gggattgaca tctcttatac ccgtaccggt gatgtctatc agacaccttt
     1681 tgagaaggca cagcttgcaa atcaggcagg agtagattac tttatttcat ttcatcgaaa
     1741 cagcagtcca aaggaaaatc agtataatgg agcggaagtt ctgatttatg ataaaagcgg
     1801 gattaaatat cagatggctg agaatattct gggagctctg ggagaagtgg gattccgcga
     1861 aatcggtgta aaagagcggc cgggacttgt ggtcctcaga cgaaccagga tgccggctct
     1921 tttaatagaa accggattta tcaattccga agaagataat aaactgtttg ataacaagtt
     1981 tagcgatata gctcagggaa ttgcagatgc gattcttgga agcctggatg aggaaacagt
     2041 gcaggaaccg ctttattaca gagtgcagac tggagcgttc agaaaaaaag agaatgcgga
     2101 ccgtatgtta tatcagttac tggaaaaagg ttatccctct tttatgttac atgaaaacgg
     2161 attgtataaa gttcagacag gtgcctatca gcagattggt aatgcagtaa atatggagca
     2221 gagactgagg gatgatggtt acagtacggt tattgtgaca aaatagcctt ctggaaatat
     2281 tggaagtctg tgcatcgcga agcgtgttgc tgtgaataga gtgaacagta acataagcag
     2341 tgggggatat agttttaaga attaacttgg ttgtacgtta atagaaaaaa tatggtacac
     2401 tgtatctatc tatagaaatt ccatagaaat cttcgtaaat aatgcatatt gttccggttc
     2461 atcagagcgt gaaattctgt tggactgtta caaacgcatt atttgagagg tgctgtagaa
     2521 aaaacagata acgaggagtt agtaatgatg aatgacgtat atgaaaaatt tttaaaaagt
     2581 tcagaagagt ttatttttgc agaaaacaag ccggaaaaat ctgatattat ttttgtccct
     2641 ggaaatggtt atccgcagat ggcggaaaaa gcagcagaat tgtttaagaa agggatggcg
     2701 gactgggttc tgcccagtgg aaaatacagc gtagtaaatg gaaagttttc aggcgttctt
     2761 gaaaaaagca atgtatataa taaggaatat ggaacagaat gggaatttct cagggatgtt
     2821 cttataaaaa acggagttcc ggatcagaaa atcctgaaag aagatcaggc aacctttact
     2881 tatgagaacg caatttattc cagacaggtg acagatcatg cagaactgga aatagaaaga
     2941 gcgattttgt gctgcaaatc ttaccatgca agaagatgtc tgatgtatta tcagctcttg
     3001 tatccgaaaa cagaatttta tgtggtgcct gtgaatgcag atggaattac cagagaaaac
     3061 tggagaaaga acgaagaagg aattgatgcg gttacaggag aactctccag aatcgtgaaa
     3121 caattttcac tgatgctgga gagatgacag ttacggctgt tcttctgttt cagttttctt
     3181 ctcgggaagc cagatgtgga caagttcgat tctgtttttg tccagacggt caacaaccag
     3241 gcggatgcca ctttcaagtg tgacagactg accctctttg ggaaggcagt caagctgttc
     3301 aataatatat ccgccaatag aatcataatc ttcagattcc agattaatat ggagggcttc
     3361 gttgatatca tccagcttgg cagaaccctg aacaacatat tctctttcag gctggatttc
     3421 tttaatatct tcgacttcat cctcatcgta ttcgtcgcga atctcaccta cgatctcttc
     3481 caacaggtct tccaatgtga ccagaccggc tgtggcaccg tattcgtcca gaacgattgc
     3541 cagattgacg gatgctttac gcatttcgat catcaggtct gctgtagctt tgtattcata
     3601 ggtaaaataa ggctcacgca ggatgttgcg gattgaaaaa ggtttgtcct ttggataaac
     3661 aagaagatct ttcatattga taataccgat tacgttatca gtgttgtcct cataaaccgg
     3721 aaaacgggta tgcatatctt cactgaagac cgccataagt tcatcatagg aaaaattgat
     3781 atctataaag gtcatgtcga ttctgggaat catgacatct tttgcagttg aatcgccaaa
     3841 atcaaacaca ttgtagatca tctgtttttc ttcgttttca atgacgccgt ctttttcacc
     3901 tacattgacg agggtacgca gttcatgttc agtcatggca tttgcctttt cgtccgggtt
     3961 aacatgcaga atgaccagta caccttctgt tattttattt acaatgaaaa caacgggagt
     4021 aaggagaatc ataagcccgt atattattct tgaataggcc agggacaatt tttcagcatg
     4081 gattgttgcc aggtttttgg gggttatctc accgaaaatg agaatcagca gagtcaggat
     4141 gccggttgtg attcctacat atgcgtttcc cagaatcttt atggtgagtg tagtcatgag
     4201 agaagaaaca gacatattta caatgttgtt tccgattaat acggtactga gcatctttgg
     4261 ggaatcggaa attatttttt ccagaataac agcacgtttg ttgccctgct cggcaagaga
     4321 ctgtatccga atcttattta cggttgtcat agcggtttcc gcagaagaaa aaaatgaaga
     4381 aagtgcgatc agtatcagaa tcgccactgt ctgaaaggca atacttgaat ccaagattta
     4441 ttcactcctt ttgattatct ttattgattg aatcatatca taaaacattt aagcaaaata
     4501 tacatgattt catataaaaa atcaagaaaa agcttttggt tcaaagatag tataaaaaaa
     4561 tttaaaagag gactgtcgaa aaagtaagat ttgtgttata attcactcga ttaaaatgaa
     4621 aaaaaacatt acagaatatt tacaaaatga taaaagtttg ataatataca gatatgtaat
     4681 attgttgtat tatgtaaaaa gagaactgat atttggctga aagtaaaaaa atgattatca
     4741 ggaaacataa gaatcgaata taaatataga ggtgcgatat gtccaataat ataaatagaa
     4801 taagaaaaaa taaattaaaa ggaacgggta tttttgcggc agcggcttta acagcggctt
     4861 tgattgcagg aaataatata ccgggtgtaa caagacaggt cagtgcggct gagtcacagg
     4921 agaatactgt gtcttctctg atcccggaca acatcacgct tgataagcct gtagaacttg
     4981 cggatgtaga acttccggca acggaatatg gaacttttga atgggcagat ggaagtttcg
     5041 ttcctgcaca gcgtgtacag agctgtgagg tacttcttat accggcagaa gggcaggatt
     5101 taagccatgt ggatggatgg gatccggaga gcggcgcggt tgtcggttac atcaatgtaa
     5161 tagtgaacag tattacggat agtgataatg ttgataagac agaaggctca ggtaaaacag
     5221 atccaacaga aaatgcagat ccaacagaaa cgcctgaaac ttcgtcagaa aaacctgccg
     5281 cagatgaaaa cgctgataca gacaataaag aagataagga aagtaaatca gatcaggata
     5341 ataaaactga tacagacaat gaagagaata agattgaaga agataaaaca gataataaaa
     5401 acaacaaaga taataacagc aatgcagata agacggataa agatacagaa actaccggta
     5461 agctggaacc tgcagatgat atgacacagg ataaagaaga tacgaagaaa gatgatgaag
     5521 atggcgcaga tgataatatc tttgataatc ctgttctgcc ggacgataag gatgaccgtc
     5581 ctacagatgc agaggattct ctttctgatg aagaaaaaga agagagggcc gcacttaatc
     5641 atacctgcga cggtattaca gtaagcggag ttaatcttcc atggtatgta cagttcagag
     5701 tttcaagcgg tgacagctat cagtttacca atgaatcaga tgcaatgatt ttccagtctt
     5761 atgaatttga actctgggat cttaagaata atacagaata tgagatccct aatggagatt
     5821 atatcagtgt cactgtgccg gtaaaatccg gatatcagta tactatcgaa catctcctgg
     5881 ataacggggc aactgagacg attattccga gtgtagagaa tggtattatg gtattcagca
     5941 cacattcttt cagtccattt ggaattgcag gaagcagaca attagtagga cctgatgcgg
     6001 ggaatgatac ggacgacaca gatgcggtaa ctcctgcacc ggcttcctcc gacagtcaga
     6061 gtcctgattc cggaaagaac aatacagtat ctatgaatga cagttctgac agcaataatg
     6121 gttcttcttc tgatcagaat gataatttaa cggaaaataa agctgtgaaa aataacaata
     6181 cagtaaatac cggagataca acatcaatta tgccgtttgt gatactgttt gtggcagctg
     6241 cagtgatcgc cggtgtggct gtatttataa aaaaaagaaa gaaataaaag aataacactg
     6301 attcctcccc catatagttt aacaggaggg gaagcaatga aagtcagagc aattttgaaa
     6361 tcactattat ttgcatatgc attaacagga gtggcattac tgcttttggc cctggtactg
     6421 tttgcttttg atctgggaga aacagctgta gatgcgggga ttattataat ttatgtactt
     6481 gcatgtttca tgggaggctt tatggccggc aaaattgtgc gtaaagacaa atatctgtgg
     6541 ggtgttatca caggtctggc ttactatgta ttactgttga ctgtctctgt tatggcaaaa
     6601 ggcggctggg atatgagtgc agcccatgca gttacaacat tttttatgtg cacaggcggt
     6661 ggaacactgg gtggaatgct gtcgtaaaaa aaagctttta aaatgaaaag atatatgata
     6721 tactatgcca agaatataat tacataagga ggatagagtt atggaacata tcaaaaccct
     6781 gaatacaaag aatttacaga acactgtaaa aaaaggtgga tgtggcgagt gccagacttc
     6841 ctgccagtcc gcatgtaaaa cttcctgtac agtaggaaac cagagctgcg agcagaaata
     6901 agatcagcta tggagaaatg agataagcag cggaactttt attccgctgc ttatcttacg
     6961 cttagaaagg attttagtaa aatgagtctg attcaccgtt ataaaagcaa tggctttaat
     7021 attgtactgg atatcaacag tggatgcatc catctggtag atgaggttac atatgaggtt
     7081 cttccatatc tggaagaggg ccttggcgca gaagctattg cagagaaact ggaaaacaaa
     7141 tataacagag aagatattga gacatctgta agagaatgta ataagctgaa agaagatgga
     7201 atgcttttta caaaagatgt ttatgagaat gtaattgaag aattttcaaa taaccggcag
     7261 accgttgtaa aagcattgtg cctgcacatt gctcatgact gcaatctggc ctgccgttat
     7321 tgttttgccg aagaaggcga atatcatggc agaagagctc ttatgtccta tgaagtcggc
     7381 aaaaaagctc ttgatttcct gatcgcgaac tccggttcca gaaaaaacct ggaagtagat
     7441 ttctttggcg gtgagccgct gatgaactgg caggttgtaa aagacctagt gaaatatggc
     7501 agagagcagg aaaagcttca caataagaaa ttccgtttca ctttaacaac aaacggagtt
     7561 cttctgaatg atgaagtaat ggaattctgc aataaagaga tgggcaacgt tgtactcagt
     7621 gtggacggac gtaaggaagt acatgactac atgcgtccat tcagaaaagg tgcaggaagc
     7681 tatgatctga tcatgccgaa gttccagaag tttgcagaat ccagaaatca ggacaagtat
     7741 tatgtaagag gtacttttac ccaccataat cttgatttct ccaaggatgt gcttcatctg
     7801 gcagatcttg gatttaaaca gatttccgta gagcctgtag ttgcggctga tacggaggaa
     7861 tatgcgatcc gtgaggagga tatcccccag atcatggaag agtatgatac tcttgcaaaa
     7921 gaaatgatta aaagagagaa agaggggaaa ggatttaact tcttccattt tatgatcgac
     7981 cttacaggtg gcccttgtgt atacaagaga ctgtcaggtt gcggttcagg aacagagtac
     8041 ctggctgtaa caccctgggg tgatttttac ccatgtcacc agtttgttgg tgaagaacag
     8101 tatctcatgg gaaatgtaga cgaaggcatt acaaagccgg aaatccagaa ggaattcggc
     8161 ggatgcaacg tttacacaaa gaaagactgc aaagactgct tcgcacgttt ctactgtagt
     8221 ggcggatgtg cggcaaatgc attccatttc catggagata tcaaaggcaa ttatgaaatc
     8281 ggatgcgaac tccagagaaa acgtgtggag tgcgccatca tgataaaagc cgcactggca
     8341 tgtgattagt gggcagtaat ctgtctgact gataccgccg tcggctgtta tcataacaga
     8401 aaatggctgg caggcggatg aacatgaccg cggacaaaaa atcaagaagg gaaaagaact
     8461 atgaagaaaa gtaaaggaat cgtagtgctg cttctgacac tgatcctgac tgtgttcttt
     8521 tgctttactg cagccgtagg tatcggtcct accggaaccg gtgcagcaaa acatatcaac
     8581 acgggtcttg atcttgccgg tggtgtcagc attacctacc aggctaagga aagcaatccg
     8641 acaagcgaag agatgtcaga tacgatctac aagcttcaga agcgtgtaga gcagtacagt
     8701 actgaggctc aggtatacca ggaaggatca gaccgtatta cagttgaaat tcctggtgtt
     8761 acagatgcag atactattct gaatgatctg ggtaaaccag gttccctgta tttcatcaca
     8821 aaagaagatg ctgacggaaa ccagaacttt actacaggac aggatggata tgttctctcc
     8881 agaactatgg atgagatcaa ggaatccgga agtgttgttc tggaaggttc tgatgtagca
     8941 gatgcccagg gtggtgcgat tcagaatcag aacacaagtg caaaggaata tgtggtaagt
     9001 cttactctta cttctgatgg agaaaacagt ggtaaaacaa aatttgcaga agctacaaag
     9061 aataatgtag gcaagcagat cgctatcgtc tatgacaata acattatcag tgctccgaat
     9121 gtaaatgaag agatttccgg tggaaaagca cagatcagcg gaatgtctga cctggaagaa
     9181 gcacagaacc ttgcttctta tatccgtatc ggttctctgg gactggaact ggaagaactt
     9241 cgttccagtg ttgtagctgc acagcttggt gaagaagcaa tctctacaag tgttcttgca
     9301 ggtgcaatcg gtctgatcat cgttattatc tttatgatca ttgcataccg catacctggt
     9361 atagttgcag gtattgcact gattctttat acatcattaa tgctgattac gctgaatgcc
     9421 tttgatatta ctcttactct tccgggtatt gcgggtatta tccttggtat cggtatggcg
     9481 gtggatgcca atgttattat ttatgcccga atcagagagg aaattggtgc aggagtctca
     9541 gtaaggaatt ctattaagtc cggtttcagc aaagctttct ctgcaatctt tgatggaaat
     9601 attacaacgc tgatcgcagc ctttgtgctg atgtggcttg gttcaggtac tgttaaggga
     9661 tttgcttata cacttgccct tggtatcgtg atctccatgt ttacagcact ggttgtatcc
     9721 agactgattg taaatgcact ttatgcagtt ggtgtacgtg atccgaaatt ctacggatct
     9781 gcaaaagaac gtaaggcagt tgatttcctt ggaaagaaga aagtattttt tgctatttct
     9841 attatcctga tcctctgcgg tccggcagcg atgtttgcta attcgcatgc aggaaacaaa
     9901 gcgttaaatt acagccttga gttctcaggc ggtacttcta caactgttac atttaatgaa
     9961 gatatggata ttaagaccat tgattccaaa gtaactcctg ttgtagaaga ggtgacagga
    10021 gataagaatg ttcagcctac aaaggt
//
