LOCUS       c00021_gnlPro..        15656 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DNAMCMNH_21.
ACCESSION   c00021_gnlPro..
VERSION     c00021_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 23:12:22
            Original ID  :: gnl|Prokka|DNAMCMNH_21
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 72538
            Orig. end    :: 88194
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15656
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[82538:87750]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..15212
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..15656
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15656
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             complement(1484..1729)
                     /locus_tag="ctg21_64"
                     /transl_table=11
                     /translation="MEYVYKTQGTCSTNIELNVEDGVVKEVAFWGGCNGNLQGISRLVR
                     GMKVEEVIAKLEGVRCGGRPTSCPDQLCRALHEMGY"
     CDS             complement(1739..2476)
                     /locus_tag="ctg21_65"
                     /transl_table=11
                     /translation="MGRAFEYRKAAKLKRWGHMAKTFTRLGKQIAIAVKAGGPEPENNP
                     TLRSVIATCKRENMPKDNIERAIKNALGKDQSDYKSMTYEGYGPHGIAVFVDTLTDNTT
                     RTVADVRSVFNKFGGNLGTMGSLAFLFDHKCVFTFKKKDGLDMEELILDLIDYDVEDEY
                     EEDDEEGTITIYGNPKSYAAIQKHLEECGFEDVGGDFTYIPNDLKEVTPEQRETLDKMI
                     ERLEEFDDVQTVYTNMQPEEGEE"
     CDS             complement(2510..4972)
                     /locus_tag="ctg21_66"
                     /transl_table=11
                     /translation="MNISYNWLKEYVNFDLTPDETAAALTSIGLETGGVEEVQTIKGGL
                     EGLVIGEVLTCTEHPNSDHLHITTVNLGDGEPVQIVCGAPNVAAGQKVVVATLGTKLYD
                     GDECFTIKKSKIRGVESTGMICAEDEIGIGTDHAGIIVLPETAVPGTLAKDYYNIKSDY
                     VLEVDITPNRADACSHYGVARDLYAYLIQNGRQATLQRPSVDGFKVENHDLNIEVKVEN
                     SEACPHYAGVTVKGVTVKESPEWLQNKLRLIGVRPINNVVDITNYIVHAFGQPLHCFDA
                     GKIKGNEVIVKTMPEGTPFVTLDEVERKLNERDLMICNKEEAMCIAGVFGGLDSGSTEA
                     TTDVFIESAYFHPTWVRKTARRHGLNTDASFRFERGIDPNGVIYCLKLAALMVKELAGG
                     TISSEIKDVFTTPAQDFIVDLAYEKVHSLVGKVIPVETIKSIVTSLEMKITNETAEGLT
                     LAVPPYRVDVQRDCDVIEDILRIYGYNNVEIPTTLNSSLTTKGEHDKSNKLQNLIAEQL
                     VGCGFNEILNNSLTRAAYYDGLEAYPSNHLVMLLNPLSADLNAMRQTLLFGGLESIAHN
                     ANRKNADLKFFEFGNCYYFNADKKNEEKVLAPYSEDYHLGLWVTGKKVSNSWAHADENS
                     SVYELKAYVENILKRLGLDLHNLVVGNLTDDVFAAALSVNTKGGKRLASFGIVTKKLLK
                     AFDIDNEVYYADLNWKELMKAIRSVKISYKEISKFPAVKRDLALLLDKNIQFAEIEKIA
                     YETEKKLLKEVELFDVYEGKNLEAGKKSYAVSFLLQDENQTLNDKMIDKIMSKLVKNLE
                     DKLGAKLR"
     CDS             complement(5085..6647)
                     /locus_tag="ctg21_67"
                     /transl_table=11
                     /translation="MAEQKRNTRNTKSTKVQPVNDYGRIQPQAPELEEAVLGALMIEKD
                     AYSLVSEILRPESFYEHRHQLIYSAITDLAVNQKPVDILTVKEQLSKRGELEEVGGPFY
                     ITQLSSKVASSAHIEYHARIIAQKSLARELITFTSNIQSKAFDETLDVDDLMQEAEGKL
                     FEISQQNMKKDYTQINPVIDEAYKLIQKAAARTDGLSGLESGFTKLDKMTSGWQNSDLI
                     IIAARPAMGKTAFVLSMAKNIAVDYRNPVALFSLEMSNVQLVNRLIANVCEIPSEKIKS
                     GQLANYEWQQLDYKLKNLMDAPLYVDDTPSLSVFELRTKARRLVREHGVRIIIIDYLQL
                     MNASGMAFGSRQEEVSTISRSLKGLAKELNIPIIALSQLNRGVESREGIDGKRPQLSDL
                     RESGAIEQDADMVCFIHRPEYYKIYQDDRGNDLRGMAEIVIAKHRNGAVGEVLLRFKGE
                     FTRFSNPEDDMVIPMPGEPAGAMLGSKMNTGDAGSMPPPPAPDFAPQTANPFGAPGDGP
                     LPF"
     CDS             6882..7712
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GHMP_kinases_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GHMP_kinases_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg21_68"
                     /sec_met_domain="GHMP_kinases_C (E-value: 5.7e-10,
                     bitscore: 31.9, seeds: 112, tool: rule-based-clusters)"
                     /sec_met_domain="GHMP_kinases_N (E-value: 5.7e-10,
                     bitscore: 31.7, seeds: 447, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLAFPNIKINLGLSITEKRPDGYHNLETVFYPVALEDALEIRTSS
                     ETEKKIILHQYGMEIAGNPEDNLVAKAYSLLDKEFHLPPVEIHLYKHIPSGAGLGGGSS
                     DAAFMLKLLNDHFQLELSEEQLEVYAATLGADCAFFIKNKPTYAEGIGNLFSPIELSLS
                     GYQIMIVKPNVFVSTREAFSNIHPHRPEYPVKEAILRPVAEWKDILINDFEASVFPQHP
                     VIGEIKEELYHQGAIYASMSGSGSSVFGLFAPGFVLPEIDWGTDVFCFKGTLNK"
     CDS             complement(7745..8107)
                     /locus_tag="ctg21_69"
                     /transl_table=11
                     /translation="MTKITKEQYEFALARVEELLPLVDDSTPANDKSMVELSVMSDIVI
                     AYEKEHFPIEKPTVAELIELSLEEKGMTQKQLASEIGVSPSRVNDYISGRSEPTLKIAR
                     LLCRVLNIHPAAMLGF"
     CDS             complement(8118..8417)
                     /locus_tag="ctg21_70"
                     /transl_table=11
                     /translation="MRVVSHKKLKDFYETKGCEDSRVALERWYDIAEKAEWRNLSDIKA
                     DFLSTDYVGNQHYVFNIRGNNYRLVVVVKFTVGYIFVRWVGTHKEYDKIDCSTI"
     CDS             8502..8624
                     /locus_tag="ctg21_71"
                     /transl_table=11
                     /translation="MLGVPKKRYHDSRRSTVTTQTQNKTRQNYYAIFPVYAGEA"
     CDS             complement(8742..9776)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GDP_Man_Dehyd"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg21_72"
                     /sec_met_domain="GDP_Man_Dehyd (E-value: 1.4e-51, bitscore:
                     168.1, seeds: 258, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKERILVTGGTGYIGSHTVVELQNSGYEVIIIDNLSNSSADVVDN
                     IEKVSGIRPVFEKLDCLDFAGLDAVFAKYKGIKAIIHFAASKAVGESVQKPLLYYRNNL
                     VSLINLLELMPKHGVEGIVFSSSCTVYGQPDELPVTEKAPIKKAESPYGNTKQINEEII
                     RDTVASGAPINAIMLRYFNPIGAHPTALLGELPNGVPQNLIPYLTQTAIGIREKLSVFG
                     DDYDTPDGSCIRDFINVVDLAKAHVIAIRRILKKKQKEKVEVFNIGTGRGVSVLELING
                     FEKATGVKLNYQIVGRRAGDIEKVWANPDFANKELGWKAVETLEDTLRSAWNWQLKLRE
                     RGIQ"
     CDS             complement(10001..10573)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg21_73"
                     /sec_met_domain="Rnf-Nqr (E-value: 1.4e-62, bitscore:
                     203.1, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYILIFISAIFVNNIVLSQFLGICPFLGVSKKVETAMGMSAAVA
                     FVLTIATIVTFLIQKFVLDVFGLGYLQTITFILVIAGLVQMVEIILKKVSPALYQALGV
                     FLPLITTNCCILGVAILVIQKDYDLLTGVVYAFSTAIGFGLALVLFAGLREQMSLVKIP
                     KGMQGTPIALITAGLLAMAFMGFSGVV"
     CDS             complement(10596..11180)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg21_74"
                     /sec_met_domain="Rnf-Nqr (E-value: 3e-70, bitscore: 228.1,
                     seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNFKVMMNGIIKENPTFVLLLGMCPTLGTTSSAINGMGMGLATM
                     FVLICSNVVISLIKNLIPDMVRIPSFIVVIASFVTLLQMVMQAYVPGLYATLGLFIPLI
                     VVNCIVLGRAEAFAAKNNAVASMFDGIGMGLGFTIALTLLGAVREFLGTGKIFDLTIMP
                     EEYGMLVFVLAPGAFIALGYLIALINSFKKA"
     CDS             complement(11195..11911)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FMN_bind"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg21_75"
                     /sec_met_domain="FMN_bind (E-value: 1.8e-22, bitscore:
                     72.2, seeds: 891, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLVLTGVTAISVALLAYVNELTKGPIAEANAKTLNEALKKVLPE
                     FTNNPVAESDTIFSEKDGKKNVDFIVYPAKNGEELVGTAVEAKSMGFGGELKVLVGFNA
                     EGKIYNYSLLAHTETPGLGSKADKWFGAYDPAKGEKAVSHEESTKSILGMNPGEAPLTV
                     SKDGGAVDAITASTITSRAFLNAVNAAYQAYKAEGGEVNGVTGASQKAKGADADAADAA
                     TGATIKVELTDSVSAK"
     CDS             complement(11938..12930)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg21_76"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 9.4e-120,
                     bitscore: 391.7, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENKLIVSLSPHVHGGDSVQKNMYGVLIALIPAFLVSLYFFGLGA
                     LIVTATSVAACLFFEWAIGKYLMKKPTTTICDGSAIITGVLLAFNLPSNLPIWIIILGA
                     LFAIGVGKMSFGGLGCNPFNPALAGRVFLLLSFPVQMTSWPVVGQLTAYTDATTGATPL
                     ALMKQAIYGDTAALSQIPDALTLLIGQNGGCLGEVSALALLIGLVYMLWKKIITWHIPV
                     SILATVFVFAGIMHLADPEKYVSPVLQLLSGGLMLGAVFMATDYVTSPMSKKGMLIYGV
                     CIGLLTVVIRLFGAYPEGMSFAILIMNAFTPLINTYCKPKRFGEVAKKK"
     CDS             complement(12936..14273)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_10"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg21_77"
                     /sec_met_domain="Fer4_10 (E-value: 7.7e-09, bitscore: 28.0,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 4.6e-16, bitscore: 50.9,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 1.4e-50, bitscore:
                     163.5, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 5.2e-29, bitscore: 92.6,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.6e-05, bitscore: 17.7,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKTFSIGGVHPHENKLSAHQPIITAEVPAKAVILLGQHIGAPAK
                     PVVAKGDVVKVGTRIAEPAGFVSAAIHSSVSGKVAKIDTIVDASGYAKPAIFIDVEGDE
                     WEETIDRSTTLVKECELSAEEIVKKIADAGIVGLGGACFPTQVKLCPPPSFKAECVIIN
                     AVECEPYLTADHQLMLEHAEEIMVGVSILMKAVKVNKAFIGIENNKPDAIELMTKVASS
                     YAGIEVVPLKVKYPQGGEKQLIDAITKRQVASGALPISTGAVVQNVGTAFAVYEAVQKN
                     KPLFERVITVTGKSVAKPSNFLARIGTPMKQLIDACGGLPEDTGKVIGGGPMMGKALVN
                     IEVPTAKGSSGILIMNQKEAKRGEAQTCIRCAKCVSACPMGLEPYLLGALSENGDFETM
                     EKERIMDCIECGSCQFTCPANRPLLDYCRLGKGKVGAMIRARQAKK"
     CDS             complement(14298..15212)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FeS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_17"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1016:4Fe-4S dicluster domain (Score: 38.9; E-value:
                     3.3e-12)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg21_78"
                     /sec_met_domain="Fer4_7 (E-value: 4.1e-12, bitscore: 38.9,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 1.8e-08, bitscore: 26.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 3.7e-08, bitscore: 25.6,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_17 (E-value: 6.4e-08, bitscore: 25.5,
                     seeds: 82, tool: rule-based-clusters)"
                     /sec_met_domain="FeS (E-value: 1.6e-10, bitscore: 32.9,
                     seeds: 364, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.1e-05, bitscore: 17.3,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLILIAVISLGAIALVLAAILYVASKKFAVYEDPRIAQVGEVLP
                     QANCGGCGYPGCSGFADACVKAGSLDGKFCPVGGQPVMAQIADILGLAAGEAEPMVAVV
                     RCNGTCANRPRTNQYDGAKSCAIAASLYGGETGCSYGCLGCGDCVAACQFDAIHMNPET
                     GLPEVDEAKCTACGACVKACPKAIIEIRPQGKKSRRVYISCVNKDKGAVARKACTVSCI
                     GCGKCVKTCPFEAITLENNLAYIDPNKCKSCRKCVEVCPQNSIIELNFPPRKPKEEAPA
                     APKPATKVETPAAKATEAPKVTE"
     CDS             complement(15220..15612)
                     /locus_tag="ctg21_79"
                     /transl_table=11
                     /translation="VENIQGSHLSVRIVQTSACAACSAKGHCSSADSKDKIIDIIDTAA
                     SSYQVGEKVMVVGETSMGMMAVVLAFVLPFVLLIFSLFLLMAWIENELYAALLSLAVLI
                     PYYFVLWLNKTRLKQQFSFTIKPINN"
ORIGIN
        1 accgaaacga taatagcaat cgagtacaac acgaacgtac tccaacgact attgacataa
       61 tcgcccatca cctttcggga agacgtcagt cccacctgta agaacacggt gaaaggcaat
      121 tgaatactaa gtaccatctg cgaaataatc aatcctttaa acggatctcc aataaagaaa
      181 atcagcaata aggcaattcc caaagacaag agaactccca cctgcgagtg actgtccttg
      241 atatgataag actcgccgaa aatacctgca aaaatagaac ctgccgccat tccgctcgta
      301 atagttgacg aaatgcccgc catcagcaat gccaatgcaa atacaattgc cgcattactt
      361 cccaataaag gttcgagcaa agacttagcc tgttgcagtt cctctacctg aataccgctc
      421 ttaaagaaag tggcggccgc cagcagaatc atggcactgt taatcgccca accaacaatc
      481 attgagaaaa gagtgtcaaa caactcatat ttcaatacct tcttaataga agcatcatct
      541 ttcttattgt actcgtgact ctgtatcacc tccgaatgaa ggaacagatt gtgaggcatc
      601 actaccgctc ccaacacact catgataatc agcatactac ctttcgggaa agaaggagtc
      661 acccaccccg ccgttgcagc cggccagtct atttccacca gaaacaactc ataaataaat
      721 gaaagcccga taacagaaac gaacgcaatg atggaacgtt ctatcttttt atacgaatta
      781 gtgaaaagca tgatggagac aaaaagcgta gtcaatacag ctccccatat aataggaata
      841 tccaataaca tttccaacgc gatggcacct cccagaattt ccgccaggga agtagagatc
      901 gacgccagta ctgctgtacc aagaataggt cgtgacaccc atttaggagt gtacttagtg
      961 gccgcctccg aaaggcaaag tccggtaacg attcccaagt gagcaacatt gtgctgaagg
     1021 acaatcagca tgatagtaga caaggtaacc acccaaagca aggaatagcc gaattcggaa
     1081 ccggcggcga aattagaagc ccagtttccc ggatcaataa atcctacagt aaccagtagc
     1141 cccggaccaa tatatttaaa aacatccagt ccacccagat agcgtttatg atctttgcgt
     1201 cttaagtctt gaaaaatatt cttcattttt gcataatagt ttatccagta caaatatact
     1261 tataaataac gagtgagaat caattttagt tcaaaatacc aaccaataag tagatgacct
     1321 atggacacag atgatacact aattatgagg acattattat aaaaggattg agtaaggact
     1381 actcgagaaa aggcaataag gactttctgc aaaaaaatga cctccgacaa accaattgcc
     1441 agaggtcaca aatcaatata taatttacat aaatgaagat caatcaatat cccatctcat
     1501 gcaatgcacg acataattga tcgggacaag atgtcggcct gccaccacaa cgcactcctt
     1561 caagttttgc gatcacttcc tccaccttca ttcctctcac aaggcgggaa ataccttgaa
     1621 ggttaccatt acatcctccc cagaaagcaa cttccttcac cactccatct tccacattca
     1681 gttcgatatt cgtgctgcaa gttccctggg tcttataaac atattccata accttacttt
     1741 actcttcccc ttcttccggt tgcatattgg tatagacagt ctgcacgtca tcaaattctt
     1801 ccaaacgttc gatcatctta tccaatgttt cgcgttgttc cggagtaacc tctttcaagt
     1861 cgttcgggat ataagtgaag tctccaccga catcttcaaa gccacattct tccaaatgct
     1921 tctgaatagc ggcgtagctc ttaggattac catagatagt aattgttccc tcttcatcat
     1981 cttcttcata ttcatcttcc acgtcatagt cgatcagatc gagaatcagt tcttccatat
     2041 ccaatccgtc tttcttcttg aaagtgaaca cacatttgtg gtcgaaaagg aacgcaagag
     2101 aacccattgt acccagattg ccaccgaact tattgaatac cgaacgaaca tcagccactg
     2161 tacgagtcgt gttgtctgtc aatgtgtcta caaacacagc aataccgtga gggccatatc
     2221 cttcataagt catgctcttg tagtcgctct ggtctttacc caacgcgttt ttaatagcac
     2281 gttcaatgtt atccttcggc atgttttcac gcttacaagt agcgatcacc gaacgcagcg
     2341 tcgggttgtt ttcaggttcc ggaccgcctg cctttacagc gatagcgatt tgtttaccca
     2401 gtcttgtaaa agttttagcc atgtggcccc atcttttcag tttagcggcc tttctatatt
     2461 caaatgctct tcccattggt ttatattttt aataatgaca attttaagtt tatctaagtt
     2521 tggcacccag tttatcttcc aggttcttca ccagtttcga catgatctta tcaatcatct
     2581 tatcattcaa agtctggttt tcatcctgaa gcaggaagct caccgcatac gacttcttac
     2641 ccgcttcgag gttcttacct tcatatacat cgaagagttc cacttctttc aacagcttct
     2701 tctctgtttc gtatgcaatc ttttcgattt cggcaaattg tatattctta tcaagcaaca
     2761 atgccaagtc gcgtttcaca gcagggaatt tggaaatttc cttgtagctg atcttcacag
     2821 aacggatggc tttcatcaat tccttccagt tcaagtcggc gtaatatact tcattgtcga
     2881 tatcaaatgc tttcaacagc ttcttagtta caataccgaa agaagcaaga cgttttccgc
     2941 cctttgtgtt gacagagagt gcggcagcaa aaacatcgtc tgtcagatta cctacaacca
     3001 gattgtgcaa atccagtccc agacgcttca atatattttc tacgtacgct ttcaattcat
     3061 acaccgaact attttcatct gcatgcgccc atgagttgga aaccttctta ccggttaccc
     3121 acaagcccaa gtgataatct tccgaataag gagctagtac cttctcttca ttcttcttgt
     3181 cagcattgaa ataataacag ttaccgaatt cgaagaattt caaatcagcg ttcttacgat
     3241 tggcgttatg agcaatgctt tccagtccgc cgaacagcaa agtctgacgc atagcgttca
     3301 aatcagcact caacggattg agcaacatca ccaggtgatt ggacggataa gcctccaacc
     3361 catcataata agcagcacga gtcagtgagt tgttcagaat ttcattgaat ccgcaaccca
     3421 ccaattgctc tgcaatcaga ttctgtaatt tatttgactt gtcgtgctca ccctttgtag
     3481 tcagactgga gttcagcgta gtcggaattt ccacattatt atatccatag atacgaagaa
     3541 tatcttcaat cacatcgcaa tcacgctgca cgtctacacg ataaggagga acagccagtg
     3601 tcagtccttc tgccgtttca ttggtaatct tcatttccag gctggtcaca atgctcttga
     3661 ttgtctctac cggaatcact ttacctacca aagaatgtac tttttcgtaa gcaagatcga
     3721 cgataaaatc ctgtgcagga gtagtgaata catcttttat ttcagaagaa atcgtaccgc
     3781 cagccagttc tttcaccatc aaagcagcca gtttcaagca ataaatcaca ccgttcggat
     3841 cgataccacg ttcgaaacgg aaagaagcat ccgtattcaa gccatgacga cgagccgtct
     3901 tacgcaccca tgtaggatgg aaataagcac tttcgatgaa tacgtctgtc gtagcttccg
     3961 tagaaccgga gtccagtcca ccgaatacgc cggcaataca catggcctct tccttgttgc
     4021 aaatcatcag gtcgcgttcg ttcaacttac gttccacttc atccagcgta acgaacggag
     4081 taccttcggg cattgttttc acaatcactt cgttgccttt aatctttccg gcatcgaagc
     4141 aatgcaacgg ctgaccgaaa gcatgaacga tatagttcgt aatatccact acattattaa
     4201 taggacgcac accgatcagg cgcaatttgt tttgcagcca ttccggactc tccttcactg
     4261 ttacaccttt cacggtaaca ccggcataat gcggacaagc ttcgctgttt tcaaccttca
     4321 cttcgatatt caagtcatgg ttttccactt taaagccatc cactgacggg cgttgtaaag
     4381 ttgcctgacg accgttctga atcagataag catacaggtc acgagctacc ccatagtgag
     4441 agcaggcatc cgcacggtta ggcgtgatat ccacttccag tacataatcg ctcttgatat
     4501 tataataatc cttggcaagc gtacccggaa cagcagtttc cggcaatacg atgatacctg
     4561 catgatccgt accgatccca atttcgtctt cagcacaaat catacctgta gattctaccc
     4621 cacggatttt tgatttcttg atggtaaaac attcgtcacc gtcataaagt ttcgtaccta
     4681 aagtagctac caccactttc tgtccggcag ccacattcgg ggcaccacaa acaatctgta
     4741 ccggttcacc gtctcccaga ttaacagtag taatatgcaa atggtcagag ttaggatgtt
     4801 ccgtgcaggt cagcacttca ccgatcacaa gtccttccaa accaccttta atggtttgca
     4861 cttcttctac accacctgtt tccaagccga tagaagtcaa cgcagcagcc gtttcatcgg
     4921 gcgtcaggtc gaagttgaca tactctttca gccagttata agagatattc atatacttaa
     4981 ttttttattg tttctcaaaa agattcgcaa agttaataag atttttcggt tgaccgagaa
     5041 ggtttgataa aaaattgcgc gttatttcac cacagaggac gcaactagaa cggcaaaggt
     5101 ccatcccccg gtgctccgaa cggattcgct gtctgcggtg caaaatcagg cgcgggagga
     5161 ggaggcatcg agccggcatc acctgtattc atcttcgatc ctaacatagc cccggcaggc
     5221 tcacccggca tcgggataac catatcgtcc tccggattgg agaaacgggt aaattctccc
     5281 ttaaaccgga gcagcacctc gcctaccgca ccattacgat gcttggcgat gacaatctcc
     5341 gccataccac gcaggtcatt accacgatca tcctgataaa tcttatagta ttccggacgg
     5401 tggataaagc acaccatatc ggcatcctgc tcgatggctc ccgattcacg aaggtcactc
     5461 aactgcggac gtttaccatc aataccttca cgactttcca caccacgatt caactgcgac
     5521 agtgcgataa tcggaatatt caactctttc gccagtcctt tcaacgaacg ggaaatggta
     5581 ctaacctctt cctggcggct accaaacgcc ataccgctcg cattcatcaa ctgaaggtag
     5641 tcaataataa tgattctcac cccatgttca cgtaccagac gacgcgcttt tgttcgaagt
     5701 tcaaatacag acagagacgg agtatcatcc acgtaaagcg gtgcatccat cagattcttc
     5761 agtttatagt ccaattgctg ccattcataa tttgccaact gtccactttt gatcttctca
     5821 ctcggaatct cacagacatt cgcaatcaaa cggttcacca actgaacgtt actcatttca
     5881 agcgagaaca acgccaccgg gttccgataa tcgacagcaa tattcttagc catagaaagg
     5941 acaaaggcgg tcttacccat cgcaggacgt gcagcgataa tgataaggtc ggaattctgc
     6001 caaccggaag tcatcttgtc gagctttgta aaaccactct caagaccact caaaccgtcg
     6061 gttcgcgccg cagccttctg aatcagctta taggcttcgt caatcaccgg attgatctgc
     6121 gtataatcct ttttcatgtt ctgctgcgaa atctcaaaaa gtttaccttc cgcttcctgc
     6181 atcaagtcgt ccacatccag cgtttcatca aacgccttac tctggatatt gcttgtaaac
     6241 gtaatcaact cacgcgccaa agatttttgc gcaataatac gggcgtgata ctcaatatgc
     6301 gctgatgaag ccaccttact actcaattga gtaatataga acgggcctcc cacctcttcc
     6361 aattctccgc gtttgctaag ttgttccttt acagtcagaa tatccaccgg tttctgattc
     6421 accgcaagat cggtgatagc agaataaatc aactgatgcc ggtgttcgta aaaagattcg
     6481 ggacgaagaa tctcactcac caatgagtaa gcatcctttt caatcatcaa agctcccaga
     6541 actgcttctt ccaattcagg tgcctgtggc tgaatacgtc cataatcatt taccggttgt
     6601 accttagtag actttgtatt gcgggtattt cttttctgtt cggccatcga ggtatttact
     6661 attttacaat ttactattta ctattttacg actagacaga ctcctttata acagagtttt
     6721 tccagtcggg acgacaaaga tagaatataa tcatgaagaa tggataagga aaaatgaaga
     6781 ttttactaac tttgctcccg aattacattc aacacatgat taattgtcat gtgcggcact
     6841 gcaaatagta aatcgtaaat tgtaaaatag taaataacct tatgctcgct tttcctaata
     6901 tcaaaataaa cctgggactt tccatcacgg aaaaacgccc ggacggatat cacaatctgg
     6961 aaaccgtttt ctatccggta gccctcgaag acgctctcga aatccgtact tcttctgaaa
     7021 cagaaaagaa gattatcctc caccagtatg gcatggagat agccggcaat ccggaagaca
     7081 acctggtggc aaaggcctat tcattgctgg ataaggagtt tcatcttccc cctgtcgaaa
     7141 ttcatttata taagcatatt ccctcgggag ccggactggg gggcggttca tccgatgccg
     7201 cttttatgct gaagttgctc aatgatcatt ttcagctgga attatctgaa gaacagctgg
     7261 aggtatatgc cgccactttg ggagcggact gtgctttctt tattaaaaac aagccgacct
     7321 atgccgaagg gatcggaaac ctgttctcac caatcgagct ttcattaagc ggttaccaaa
     7381 tcatgatcgt caagccgaac gttttcgttt ctacccggga agccttttca aatatccacc
     7441 cgcaccgtcc ggaatatccg gtcaaagagg caatcctgcg tccagttgca gaatggaagg
     7501 atatcctaat caatgatttc gaagcaagtg tattcccgca acatcccgtc attggagaaa
     7561 tcaaagaaga actctatcat caaggagcaa tctacgcatc catgagcggc tccggctcat
     7621 ccgtattcgg gctgtttgct cccggattcg tcttaccgga aattgattgg ggaactgacg
     7681 tattctgctt caaaggtaca ttaaacaaat aaatctcact aacaattatg ttttgactat
     7741 tttttcaaaa tcccaacatg gcagcggggt gtatattgag tacccggcaa agcaagcgag
     7801 ctatttttaa agtaggttcc gagcgacccg aaatataatc attcacgcgt gaagggctaa
     7861 cccctatttc actggcaagc tgtttttgtg tcatcccctt ttcttcaagg gacaattcta
     7921 tcaattctgc tacggttggt ttttctatag gaaaatgttc cttctcatac gcaatcacta
     7981 tatcagacat aacagaaagc tccaccatgc tcttgtcatt tgcaggagtg ctgtcgtcca
     8041 ccaaaggcag aagttcttcg actcttgcca atgcaaattc gtattgttct ttcgttattt
     8101 tagtcatatc tattatatta tatagttgaa caatctattt tatcatactc tttatgagtt
     8161 cccacccaac ggacaaaaat gtatcccacc gtaaatttaa caaccactac cagccgatag
     8221 ttgttccctc tgatattaaa aacatagtgt tgattgccca cataatcagt cgatagaaaa
     8281 tccgctttta tatcagacaa attccgccat tctgcttttt ccgctatatc ataccaacgt
     8341 tctaaagcaa cacgtgaatc ttcacaccct ttcgtctcgt agaaatcttt caatttctta
     8401 tgtgatacta ctctcatatc ttattcattt gatacaaaat tacaaaataa ttttggataa
     8461 cagaagaatt agtgctaaat attttataaa acagaacatc catgctgggc gtaccaaaaa
     8521 aacggtacca cgactcacgt cgtagtaccg tcacaacaca aacacaaaat aaaacacgac
     8581 aaaactacta tgcaatcttt cctgtctatg ccggggaggc ataagtacta tttacgtata
     8641 ttcgcatact cataaatagc ttcaggtcga ttagcatcaa ttaaacaaat cgcatgcacg
     8701 atttgtttaa acttttatgt tatttaaaac aagtttctct tttattgaat ccctctttca
     8761 cggagtttca gctgccagtt ccatgcagag cgtaaagtat cttctaaagt ttctacggct
     8821 ttccaaccca gctctttatt agcaaaatcc gggttagccc aaactttttc aatgtcacct
     8881 gcacgacgtc cgacaatctg ataattcaat tttacgccag tggctttttc aaagccattt
     8941 attaattcca atacagaaac accacgtcct gtaccaatat taaatacttc tactttttct
     9001 ttttgtttct ttttcaagat acgacggata gcaatcacgt gtgctttagc caagtcaacg
     9061 acattgataa agtcacggat acaagaaccg tccggtgtat cataatcgtc accaaacacg
     9121 ctaagtttct cacggatacc gatggctgtc tgggtcagat atggaatcag gttttgagga
     9181 accccgttag gcagttcacc cagcaatgca gtaggatgcg cgccaatcgg gttgaaatag
     9241 cgcaacatga tcgcattgat cggagcacct gaagctaccg tatcacgaat aatctcttca
     9301 ttgatctgtt tggtatttcc ataaggtgat tccgctttct tgatcggagc tttttccgtt
     9361 accggcagct cgtccggctg accgtatact gtacaagaag aagagaacac aataccttct
     9421 actccatgtt ttggcatcag ttcgagaagg ttaatcaaag aaaccaggtt attacggtag
     9481 taaagcaacg gtttttgtac cgactctcct actgctttgc tagctgcaaa gtgaatgatt
     9541 gccttaattc ctttatattt tgcaaatact gcatccagac cggcaaagtc caaacagtcc
     9601 agcttttcaa aaactgggcg aataccggaa actttctcta tattgtcaac aacgtcggca
     9661 cttgaatttg ataaattatc gatgatgatt acttcatatc cactgttttg tagttctaca
     9721 acagtatgag acccaatgta tcctgtcccg cctgttacta aaattctttc tttcatatac
     9781 tttataaaaa atggttagtt tctcggctta ttattgtttg agttacaaat gtatggaaat
     9841 aaaatggaat tgcaataatc tgccacaaat ttatttgctg aaaagtaatt aaggtacgat
     9901 ttggtagcat ttaggtataa aaaagaattg gaaactctaa cctgtatgtc gccacacagc
     9961 agagcttcca atcctctatt taattatcaa ctgtaaatcc ttacaccacg ccggagaatc
    10021 ccatgaatgc catagcaagc aaaccggcgg taatcaaagc aatcggagtt ccttgcattc
    10081 ctttcggaat tttcacaagg ctcatctgtt cgcgcaatcc ggcaaaaagc accagtgcca
    10141 gaccgaagcc gatagctgta gaaaacgcgt acacaacacc tgtcagcagg tcatagtctt
    10201 tctgaatcac caggatagcg acaccaagaa tacaacagtt cgttgtaatc agcggcaaga
    10261 acacacccaa cgcctgatac agagccggag acaccttttt caggatgatt tccaccatct
    10321 gcaccaatcc ggcaatcacc aggataaatg taatcgtctg caagtatccc agtccgaaaa
    10381 catccagtac aaacttctga atcaggaaag tgacgatggt agcgatggtc aacacgaaag
    10441 caaccgcagc gctcataccc atcgcagttt ccaccttctt ggatacgccc aggaacggac
    10501 agatacccag gaactgcgac aacacgatgt tgtttacaaa gattgccgaa ataaatatca
    10561 atatatattc catattcttt tcttatttaa ttgaattagg ctttcttgaa actgttaatc
    10621 aacgcaatga ggtatcccaa agcgatgaaa gcgcccggag ccaatacaaa caccaacatt
    10681 ccatattctt ccggcatgat ggtcaaatcg aagattttac cggttcccaa aaactcgcgg
    10741 acagcaccca gtaaagtcag ggcgatggta aagccaagcc ccataccgat accgtcgaac
    10801 atagaagcaa ctgcgttatt cttggcagcg aaggcttcgg cacgtcccag tacaatacag
    10861 ttcactacaa tcaacggaat gaaaagaccg agtgtagcat acagtcccgg cacgtaagcc
    10921 tgcatcacca tttgaagcaa ggtcacgaag gatgcgatca ccacaataaa cgatgggata
    10981 cgcaccatgt ccggaatcag gttctttatt aaagagatca ccacattcga gcagatcaat
    11041 acgaacatgg tagccagtcc catgcccata ccattgatag ccgatgatgt agtacccaat
    11101 gtaggacaca taccgagcag gagtacaaac gtaggattct ctttgataat cccgttcatc
    11161 attactttaa agttattcat atctgtctcc tttcttattt agcactgact gaatcagtta
    11221 gttcaacttt gatcgtagct cccgtagcag cgtcagcagc atctgcgtcc gcgcctttcg
    11281 ctttttgaga agcaccggtt accccgttca cttccccgcc ttcggcctta taggcttgat
    11341 aagcagcatt cacggcattc aagaaagcac gtgaagtaat ggtagaagcc gtgatggcat
    11401 ccactgctcc tccatctttg ctgacggtca acggagcttc acccggattc atacccaaaa
    11461 tagatttcgt actctcttcg tgagatactg ctttttctcc tttcgcggga tcatacgctc
    11521 cgaaccattt gtcggcttta gagcccaatc ccggagtttc cgtgtgagcc aacaaagagt
    11581 agttatagat tttcccttcg gcattaaagc ctaccagcac tttcagttca ccgccaaatc
    11641 ccattgattt agcttcgaca gcggttccta caagttcttc accgttctta gccggataaa
    11701 cgataaagtc aacattcttc tttccgtctt tctcactgaa gatcgtatcg ctttccgcta
    11761 ccggattatt ggtaaattcg ggaagaacct ttttcaaggc ctcgttcagt gtcttcgcgt
    11821 tcgcttcggc aatggggcct tttgtcagtt catttacata agccagcaac gcaacggaaa
    11881 tagcagtcac tcccgtaagt accagcaaca tattctttaa agatgattct aactttttca
    11941 tttcttcttc gctacctccc caaagcgttt tggtttacaa taggtgttaa tcagcggagt
    12001 gaacgcattc ataatcagga tggcgaacga cataccttcg ggataggcgc cgaacagacg
    12061 gataactacc gtcagcagac cgatacatac accatagatc agcatccctt tcttactcat
    12121 cggagaagtc acatagtcgg ttgccataaa gacagcaccc agcatcagac caccggaaag
    12181 caactgcaat accggagaaa cgtatttttc cggatctgcc aggtgcatga tgcctgcaaa
    12241 gacaaacaca gtagccagga tagacacagg aatatgccag gtgatgattt tcttccagag
    12301 catataaacg agtccgatca gcagagccag tgcactcact tcacccaagc atccgccatt
    12361 ctgtccgatc aacaaggtca atgcgtccgg aatctggctt aaagcggcag tgtcaccgta
    12421 aatggcttgc ttcatcaagg ccagcggagt ggcaccggtg gtagcatccg tataagcggt
    12481 caactgtccg actaccggcc agctggtcat ctgcaccggg aaagaaagca acaggaacac
    12541 acgtcctgcc agtgccggat taaaaggatt gcaacctaat ccgccgaaag acattttgcc
    12601 tacaccgata gcaaacagtg cacccagaat gataatccag atagggagat tagacggtaa
    12661 gttgaatgcc agcaacacac ctgtgatgat ggcagagccg tcgcagatgg tagtggtagg
    12721 tttcttcatt aaatatttcc cgatcgccca ttcgaagaac aaacaagctg caacggaagt
    12781 agccgtgaca atcagggcac ccagtccgaa gaaatagaga gacaccagaa aagccggaat
    12841 cagtgcgatc agcacgccat acatattttt ctgtacgctg tctccgccat gaacgtgggg
    12901 tgatagtgat acgattaatt tattttccat attcgttatt ttttagcttg acgtgcacga
    12961 atcatagcac ctactttgcc tttgcccaga cgacagtagt cgagcagcgg acggttggca
    13021 ggacaagtga actggcaaga gccgcactcg atacaatcca tgattctttc tttttccatt
    13081 gtttcaaaat ctccgttttc ggacaaagct ccgagcaagt acggttccag tcccatcgga
    13141 caggcactca cgcacttcgc gcaacggata caggtttgag cttcgccgcg tttggcttcc
    13201 ttctgattca taatcaggat accggaactg cccttcgcag taggaacctc gatatttacg
    13261 agcgccttac ccatcatcgg accgccaccg atcaccttac ccgtatcttc gggcagaccg
    13321 ccgcaagcgt caatcaactg tttcatcggt gtaccgatac gagccaggaa gttggaaggt
    13381 ttcgcaaccg actttcctgt cacggtaatc acacgttcga acaacggctt atttttctgt
    13441 acagcttcat aaacggcaaa tgctgttccc acgttctgca cgactgctcc cgtagagata
    13501 ggcaatgcac cgctcgctac ctgacgtttg gtaatcgcgt cgatcagctg cttttcacct
    13561 ccttgcggat atttcacctt caagggcact acttcgatac ctgcatagct ggaagccact
    13621 ttggtcatca gttcgatagc atccggctta ttattttcga ttccgataaa tgccttgttc
    13681 actttcaccg ctttcatcag gatagaaaca cccaccatga tttcttccgc gtgttccagc
    13741 atcagctgat ggtcggcagt caggtaaggt tcacactcta cggcattgat aatcacacat
    13801 tcagccttga aagaaggagg aggacaaagt ttcacctgcg tagggaaaca agcaccgccc
    13861 agacctacga ttccagcatc ggcaatcttc ttcacgatct cttctgcgga aagttcacac
    13921 tctttcacca gtgtggtgct acggtcgatt gtctcttccc attcgtcgcc ttccacatca
    13981 atgaagatgg caggtttcgc ataaccgctg gcatcgacta tggtatcaat cttcgccact
    14041 ttaccactga ccgaagagtg aattgctgcc gaaacaaagc cggcaggttc ggcaatccgt
    14101 gtgcctacct ttaccacatc ccctttcgct acaaccggtt ttgcaggcgc accgatgtgc
    14161 tgccccagca aaataacagc ctttgcagga acttccgctg tgataatagg ttgatgtgcc
    14221 gacaatttat tttcgtgtgg atgaactcca ccaattgaaa atgtctttaa catacagttc
    14281 tgtatttttt tctgttatta ttctgttact ttcggagctt ctgtagcctt tgcagcagga
    14341 gtttccactt ttgtagccgg tttcggagca gccggagctt cttctttcgg tttccgcggc
    14401 gggaaattca actcgataat gctattctgc ggacaaactt ccacacattt ccggcaagat
    14461 ttacacttgt tcggatcgat gtaagccaaa ttgttttcca gcgtaatagc ctcgaacgga
    14521 caagtcttca cacacttgcc acagccgata cagctcactg tacaagcctt acgtgccaca
    14581 gctcccttgt ctttattcac acaagagata tacacgcggc gtgacttctt tccttgcgga
    14641 cggatttcga tgatcgcctt cgggcaagcc ttcacacagg cgccacaagc ggtacatttc
    14701 gcttcatcca cttccgggag ccccgtttca ggattcatgt ggatggcatc gaactgacaa
    14761 gcagccacac agtcaccaca ccccagacat ccgtaactac atcccgtttc cccaccatac
    14821 agcgaagcgg caatagcaca actcttcgca ccatcatatt ggttggtacg cggacgattg
    14881 gcacacgttc cgttacatct taccactgct accatcggtt cagcttcacc ggctgcaagt
    14941 ccgaggatat cagcaatttg tgccatgaca ggttgtccac ctacggggca gaatttacca
    15001 tccagcgaac cggctttgac gcaagcgtcg gcaaatccgc tacaaccggg atagccacat
    15061 ccaccacaat tagcctgggg aagcacttct cccacctgag caatccgcgg gtcttcatac
    15121 acggcaaatt tcttggaagc cacataaaga atagcggcca gcacgagcgc tatagctccc
    15181 aatgaaatca ctgcaatcag aatcaaattc ataatgtttt tagttattta ttggttttat
    15241 agtaaatgaa aattgttgtt tgagtcgcgt tttattgagc cacaaaacga aataataagg
    15301 tataaggaca gccagagaaa gaagtgctgc atacaactca ttctctatcc acgccatcaa
    15361 aagaaacaat gaaaatataa gaagtacgaa aggaagtacg aaagccaata ccactgccat
    15421 catgcccatc gacgtttcgc cgaccaccat caccttctct cccacctgat aggaagaagc
    15481 cgcggtatct ataatatcta tgattttgtc cttactatcc gccgaggaac aatgcccctt
    15541 tgcgctacaa gccgcgcaag ccgatgtctg gacaatcctc accgacagat gagaaccttg
    15601 tatgttttcc acaataccta gatgctttat agtattattc gtcattttgc aaactc
//
