LOCUS       c00001_gnlPro..        23228 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LBICMAHI_1.
ACCESSION   c00001_gnlPro..
VERSION     c00001_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 22:57:46
            Original ID  :: gnl|Prokka|LBICMAHI_1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 537888
            Orig. end    :: 561116
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23228
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[547888:551116]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13228
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..23228
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..23228
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="TPP_AA_metabolism"
                     /region_number="3"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             592..1905
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CT_Btheta"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_521"
                     /sec_met_domain="CT_Btheta (E-value: 5.2e-66, bitscore:
                     218.4, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSIEKINQAKAEIAATSAYKTITAFFDADSFCEIDAFAKSGEGFA
                     EVVAGFGTVEGMPVYAFAQNSDICGGAMSKAQAAKLKKLYGLALKTGAPVVGFYDSVGG
                     RLNQGTELLAGCGDVLNAAASLSGVVPQISVVLGTCLGTNALNAASADIVIMSKDAQLS
                     LSVTGKHSDAAYNAENGIASIVCDDADKAIKAAKELILYLPSNNLTMAPQSFEEAPAED
                     GCGCVVSRTVDGNSIVKLFNDYGKEANVRFARLGGQVVGIVVTKGKELGCKSANKVAKF
                     VRFCDAFSLPVVTFVNCPGFESIKSATKASAAYAEATTVKISVVTGKAIGSGYVALAGT
                     GANADVVYALPDAVISPVNVEAAAFIMAPEVMNVATDKQAEVAQKFADENLSAYNAAQN
                     GYVDGIVEEAQLRQTLISALDMLSGKRVSTLSKKHSTI"
     CDS             1944..2309
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 65.7; E-value:
                     8.2e-21)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_522"
                     /sec_met_domain="Biotin_lipoyl (E-value: 8.2e-20, bitscore:
                     65.7, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNLRITVNGTAYDVQVEELGGSSAPAAAAPAPAAAPAPAAKPAA
                     PAGAQGSVVVKAPMPGTVVNVVVSAGQAVKAGDDLVFIEAMKMETPVKAPQDGTVATVD
                     VAKGESVDSGKVLVTLN"
     CDS             2340..3743
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HMGL-like"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PYC_OADA"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_523"
                     /sec_met_domain="HMGL-like (E-value: 4.8e-48, bitscore:
                     159.2, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="PYC_OADA (E-value: 8.9e-54, bitscore:
                     177.5, seeds: 434, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKKIRVTETALRDAHQSLIATRMTTEEMLPVLDKLDKIGYYSLE
                     CWGGATYDSCLRFLNEDPWDRLRTIREHCPNTKLQMLFRGQNMLGYRHYADDCVEYLVQ
                     RSIANGIDIIRIFDALNDIKNLKTAIKAANKEGGHAQVAISYTTGPVFTDEYYVEYAKR
                     IADAGADSICIKDMAALLTPTRTESLVKAIKAAVPELPLQLHTHYTSGLASMCLLKGVE
                     AGADGIDTAISPLALGTSHAPTESMVAALSGTEFDTGLDLKQFSDIRAYFMTLREKYIK
                     SGLLDPKMLATDANALIYQVPGGMLSNLLSQLKQAGKEDKLDEVLAEVPRVRKDSGYPP
                     LVTPTSQIVGTQAVFNVITGKRYSMCTNEFKGLVAGEYGTTPMPIDPAFQKKIIGDKKI
                     IKGRPADQLEPELDKLRGEIEQWIEQPEDVLSYAQFPKVALDFFEKRRNAKVGINGDKL
                     DKKNMVHPV"
     CDS             3938..4951
                     /locus_tag="ctg1_524"
                     /transl_table=11
                     /translation="MKKLLTTLIAFVMCFSVVTTAFAATPDEASDPDLISDIKQAMLDT
                     YYGDEKPDFIEVRIYGTASDGGVYFDFMDSFTHWTDEVEFDIGDYTVSYPRDCPVLLYK
                     NNKVYTLSDAYETGVIDDDMLYELYVWGNLWGKIDVTPKGEDRALLSEIKRVIINKYYN
                     GKAPEYLNVEIVGSTSDKTVCFRNIPFMSLGVMIEQTIGDYTYYYNHGDDVMLYKNGNV
                     YSIKEAYESGVIDDSILEELSKMNFGLESNKPNTTVPTEPTTSVATVDEPVTVPDTTSA
                     TKPVSTSDTATNDTLSNSQNNSGAVQTGQNSVAVILLVAMLAGCAVIFAKRRNYFK"
     CDS             5148..7553
                     /locus_tag="ctg1_525"
                     /transl_table=11
                     /translation="MKKFLPIAMAAVMSMSAVAVSAVSANAVEPLNTPVQYAQVARASL
                     ATPKISKAESVYGGVKLTWNKVNGAAKYRVYYKGRKGWTRMVDTTSTSYIDKDVSSGRN
                     YTYTVRCISADGKSFTSGYDSKGTTVKYVAAPEISKLENVNGGVKISWGKVSGATKYRV
                     YYKGRKGWTRMVDTTSTSYIDKDVSSGRNYTYTVRCISADGKSFTSGYDSKGTTVKYVA
                     APEISKLENVNGGVKITWNKVSGASKYRIYQKNSSDWFRVSDTTSNSIVDKSVDVGTYT
                     YTVRCISDDGKSFESGFNPKGSSIRYIQAPKILETNVVNGGIKVIWDSEENTNYRLYCK
                     TEGKGWTKVCDSKTGVVTHKNLQPNKTYTYTVRAISSDAKKYLSGYDPEGISAKYVATP
                     KISKAEYTYDGIKLAWNKVAGAEKYRVYYKDATGWNKLVDTKGTSYLDKGLVSRELSVK
                     DSSVNGQYIYTVRCISSNGKVFQSGYDTKGVKSALYNNGCPEIYNIDTMHGGITLNWEA
                     AADKISKYRVYIKQNGSWKKLADTTNNYYTHKNVKAGQTYTYTVRCVSKDGKKFTSTYN
                     PSGVAFKYKTTNKTRDAYIDYLLKHESEWLPELKVGDIALAGVQFTDLDFDGVPELIAQ
                     EAGDKEYYLNARVYTFKNGKLSLVGFDNSMTYIQNRLAYLYDKSAKRYVINSAELSTSN
                     PDRYLDCENYTLSYDGNLISAHPYSSYHLALENWGLDYTYYVHGRTSKQVYNAANLSTL
                     DNCVNAHMYSQFVYCSVDGYPKLWNQFTTDQKRQYLTDSYNAFSYDKY"
     CDS             7986..9824
                     /locus_tag="ctg1_526"
                     /transl_table=11
                     /translation="MKKFLPIAMAAVMSMSAVAVSAVSANAVEPLNTPVQYAQVARASL
                     ATPKISKAESVYGGAKLTWNKVNGAAKYRVYYKGRKGWTRMVDTTSTSYIDKDVSSGRN
                     YTYTVRCISADGKSFTSGYDSKGTTVKYVAAPEISKLENVNGGVKISWGKVSGATKYRV
                     YYKGSKGWTRMVDTTSTSYIDKDVSSGRNYTYTVRCITSDAKKFTSGYNPTGKSVKYVA
                     TPKISKLEVTYDGVKLTWNKVAGAEKYRVYYKDRNGWTKLGDTTGTTMLDMNVVSKEFD
                     LSVDDIYYTVRCISKDAKSFTSGYDSKGTPIGDHQDCPEIYSIGAVNNGVEMHWTGDAP
                     KFRVYIKENGSWKKIAETYDNYYVHKGARSGSNTYTVRGVSKDGKKFTTMFNPTGVTYR
                     YKTSDKTRDAYINYMMNHQSEWMPSLGSNHNLSGVMFLDFDFDGVPELVAQKADSNEYS
                     FHSVVYKFEDGKLKRVGNVNDGFAIYYNKTAKKYEVHDLKISLNVDDGYYWSGNSIITY
                     DGENLFANMYSARGVGEESNNNIYYNYFDGNDKNISRAKYNEINLKQFNNCVNAHMFTQ
                     FIATGYGDNSVWGENTTAENKQSLLDAYNSFSYEKY"
     CDS             complement(10001..11041)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_527"
                     /sec_met_domain="IlvN (E-value: 3.8e-82, bitscore: 269.0,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 3e-59, bitscore: 194.7,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDYTKNMTAPIYYQSDCNLDLLKGKKIAIIGYGSQGHAHALNLK
                     DSGCDVIIGLYKGSKSWAKAEAQGFKVYTSAEAAKQADIIMILINDEKQAALYKNDIEP
                     NLEAGNMLMFAHGFNIHFGCIKPPKDVDVTMVAPKGPGHTVRSEYQVGKGVPCLVAVEQ
                     DATGQAKDLALAYALGIGGARAGVLETTFRTETETDLFGEQAVLCGGVCALMQAGFETL
                     CDAGYDPRNAYFECIHEMKLIVDLIYQSGFAGMRYSISNTAEYGDYITGPKIITEDTKK
                     AMRKVLSDIQDGTFAKDFLLDMSDAGSQVHFKAMRKLAAEAPAEVFGKEVRKLYSWSDE
                     DKLINN"
     CDS             complement(11102..11593)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_528"
                     /sec_met_domain="ALS_ss_C (E-value: 8.3e-29, bitscore:
                     94.9, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQYTLSILVENQAGVLSKISGLFSRRGFNIDSLAVGVTQDPSVSR
                     ITIVANGDEYIVEQLEKQLNKLIPVIKVKRLNEGEFISRELVLIKVHCAASKRAEIVKT
                     VEIMQAKIVDVSPSSVTVEYCECASRINTLVDLLKPYGIREIVRTGTVAIDRGTASVSV
                     "
     CDS             complement(11606..13228)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_529"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.3e-41, bitscore:
                     137.1, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISGAEIMVKCLEAEGVDIVFGYPGAAICPFYDKVYDSSITHILV
                     RQEQNAAHAASGYARCSNRPGVCVATSGPGATNLITGIATAYTDSIPIVAITGQVRSDL
                     LGRDVFQEADITGACEPFVKHSYLVSKTEDLPRVFKEAFHIASTGRPGPVLIDIPVDIQ
                     ENEIESFEYPESVNIIGYKPNTKGHAIQVKKAVEAINASKRPVIVSGGGVLSSGIKLKL
                     QKFAETTGIPVISTMMGIGVMPSEHELYLGMLGTHGKAVANRALHEADLVIVCGARLGD
                     RAVAAPDQMSENTKVIHIDIDPAEIGKNVKTEIPIVGDMKNVINMLLDSIGDYKVTTMW
                     SETVKNWKKDLYREPPVFDGFVEPRTLVGHLSAMFRSKAILVADVGQNQIWCANNFRIR
                     EGRFLTTGGMGTMGYSIPAAIGAKFARPDRDVIVICGDGSFQMGLNELATIAGNQLGIK
                     IIIMKNARLGMVRELQDKHYGGRHSATILNGDPDFLKIADAYGIDHAEAHSNKEAENII
                     KGIVDSEKPFILVCDVHPDTPSI"
     CDS             complement(13530..15854)
                     /locus_tag="ctg1_530"
                     /transl_table=11
                     /translation="MRYKYQLDNLNCAHCAGKIEAKIAETDGFEDVSFNFATKLLNFKS
                     EKQNPVSEIQAICDSIEDGVTVVDKTPKTNLKKYTYTLDNLNCAHCAGKIEAKIAETDG
                     FEDVSFNFATKLLNFKSEKQNPVSEIQAICDSIEDGVTVVDKTPKNDITTKAEPEITKK
                     KINRDTIFLAISIVLAVVSEILHLTLDGVTAVHYVVLAACFVATLLSGYKVFINGAKNI
                     LKLRIDETTLMSVAVIAAFCLGDFVEAAMVTILFSIGEIFEDRAVDASRRDIEKLANIR
                     PDTATIIVDGAEQVVPAESVEIGSIIEVKPYERVPLDGIIIKGKTTLDTSALTGESLPV
                     DAGEGSEVLSGAINGSNLITVKTTKHFGDSTATRILQLVEDAAAQKGNSEKLISRFASV
                     YTPVVVLIAAAIAVIPPLCGLGAFSEWLYRALVCLVASCPCAIVISVPLSYYSGIGAAS
                     EVGVLIKGGKYIEALAKADTFVFDKTGTLTSGKLSVNKVNTVGSYSADEVLALAAASEK
                     YSAHPIASAIREKANGLELPELSDYSESAGHGTSAVYNGKTIQCGGSKILSDEQKKIAN
                     KDDSVFVIYDGQLIGSLNVSDTVRPEAKEVISQLKALGVKNTVMLTGDRQQPAENVKNE
                     LGLSECHAELLPAQKLELFKGLKSKSKGACFVGDGINDAPVLSASDCGIAMGFGSEAAI
                     EASDAVLASGTLKQLPKAIKIARSVINTVKGNIIFALSIKALVIILAAFGLAQIWMSVI
                     ADTGVSVVCVLIAARLLKKKY"
     CDS             complement(15867..16184)
                     /locus_tag="ctg1_531"
                     /transl_table=11
                     /translation="MENKEKTTTPEMPDIDVLFELADLFKVFGDSTRLRIMYTISENEM
                     SVLNIAEALSMEQSTISHQLRVLRQNKLVRVRREGKQIYYSLDDDHVKRIIEMGLDHVL
                     E"
     CDS             16915..18207
                     /locus_tag="ctg1_532"
                     /transl_table=11
                     /translation="LEKFVVTGGKPLSGEVTISGAKNAAVAIIPAVILCDEPCQIENIP
                     NISDVSLISRILQQMGANVRRINRSSLYIDPTKIRTCNAVTDLVRGMRASYYLLGALLG
                     KYGKAKVALPGGCNFGVRPIDQHLKGFEALGATTQLVDGAIIEAECDSLVGTHVYLDVV
                     SVGATMNIMLAASKAKGQTIIENAAREPHIVDLANFLNSMGADVRGAGTDVIKIRGVEY
                     LHGITYSIIPDQIEAGTYMCAAAATRGCITVKNITPKHLESISAKLREMGVKITEYDEA
                     LKVDASSAPLKRCNIKTMPHPGFPTDCQPQFAALLMSVPGTSIINENVWDNRYQYVSEL
                     IRMGAQISVEGRLAIIEGGVPLTAAPVKATDLRAGAAMIIAALEINGTTEISNIQFIER
                     GYEDVVEKFRGLGADIKKVYFTGDNEQELGA"
     CDS             18330..19118
                     /locus_tag="ctg1_533"
                     /transl_table=11
                     /translation="LARAVPLFSGSKGNSYYIGSASEGVLIDAGRSCKQIENAMLANGL
                     DMGSIGAVFITHEHTDHCSALRVLAKRYGFKVYSSLGTLNALRAGNKLDPNTDADVITD
                     EVVIGNMRVQRIDTPHDAAESCCYRVTAPDGKSALIATDMGVMLPDVRTAAEQSDFVVL
                     ESNHDINMLKNGFYPYPLKQRILSNRGHLSNEACAKELVNLVEKGTLRLMLGHLSEENN
                     TVPLAMSTSVDLLTSNGMKYKSDYSLDVAPSVSTTKAIIF"
     CDS             19140..19625
                     /locus_tag="ctg1_534"
                     /transl_table=11
                     /translation="MIKINIICIGKIKEKYFTDAIAEYAKRLTAFCKFNIIELSEERIK
                     SNIPNRSQIDEVIFSEGKRIMQKISPSDYVVAMCIEGKSMSSEELSKLIDNASVSGKST
                     VDFIIGGSYGLDESVKKRADVRLSMSRMTFPHQMARMILSEQIYRAFEISSNGKYHK"
     CDS             19640..21379
                     /locus_tag="ctg1_535"
                     /transl_table=11
                     /translation="MALDGIFLRHIKSEIEKEALGARVSQIYQPNREELVFGLRTFSGN
                     KKLLLSARANSPRVNFCSSTPENPAQPPMFCMLLRKRIGGGKLVGLRQNGCDRVLMLDF
                     ECVNELGDTVMITVVCEIMGMYSNIIIVDSNGVIIDSLKRVDLTMSSKRLVLPNIKYEL
                     PESQNKLNLLKCSVLDVCTAVKNLDTEMPLNKALLRTIEGVSPIVCREIEYKVMEGATN
                     RIEGVLFDRLAVEIKKLKSVCSDCSGKPVVVYREDGKPMDFCFMNVEQYGDFAKVESEE
                     SFSDLLDGFYEARDSRDRMRVKSQSLTKLLNNTLERLARKIAKQKSELERCADREHLRI
                     CGDLLQANIYRIERGAEYVDVENFYDENNAILRIKLNPAISPSANAQKYYKDYRKAKNA
                     EIMLKEQLEKGREELDYINSVLDTVDRAENEKDLAQIREELTEQGYLKVQKGKKPRQTT
                     LPPLEFESSDGFKILVGRNNRQNDKLTLKTASKNDMWLHTKDIHGSHVIVVSDGKEISD
                     TAIYEAARLAAYHSKARNSSQVPVDCTLVRYVSKPNGSKPGMVIYVNNKTLYVKPSQTV
                     EKQ"
     CDS             complement(21688..22566)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Radical_SAM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_536"
                     /sec_met_domain="Radical_SAM (E-value: 1.9e-12, bitscore:
                     43.1, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MICNLCPRKCGAVRTAHSGNGFCKMGELPVVARVAPHYGEEPCIS
                     GTKGSGTVFFSGCTMRCVYCQNYEISNEDGGRTITPERLAECYKELEDKGVHNINLVTA
                     DHFAHAVVKSLEIYKPRIPIVYNCSGYTSPKTLSMLDGLVDIYLPDFKYADDFLAVKYS
                     SAPNYVNTAVAAIHEMTFQVGLPQFDDDGIMKKGVIVRHLILPAHTKNSLEVLDIVKRR
                     FGDQVLLSLMCQYIPMGKVSDREFSRINRKITRREYDKVKLEMMRLGIDGFTQELSSAD
                     ESYVPEWDFEG"
     CDS             complement(22657..22872)
                     /locus_tag="ctg1_537"
                     /transl_table=11
                     /translation="MITYILNHTPEDGFNTFGISAFCGKKLIKSVSGISESFREMTELV
                     EMCNELELELCQLDDIIEDYLTDFTL"
ORIGIN
        1 acccgaaaaa caatgtttac aagatttaca gagtaaccgt tcgaccgtca attgacgagg
       61 atcagcttgt aaagcttgaa acaggtgttg agcttgacgg caggaaaacc gctcctgcat
      121 atgtccatgt aattcacaag gagcagggca gagtagttct tgaaatgatt cttcacgagg
      181 gtaagaaccg tgaaatcaga agaatgtgcg aggctgtcgg gcttgaggtt gcaagactca
      241 aacgcaccca gatcggcgga gttaaaatgg gtatgctcaa acagggcgac tggagagatt
      301 tgaccgaaca agaggttaaa aaactgcttg caaacccgtt tttaaacggc aaacagcttt
      361 aattttccgt ttttgaaaaa tacttccgaa acggtcaatc aaactatttg ttaattcgac
      421 aataaattaa aggttttcac ggaataacta ttaaatgtgt tcaaaattga aatagtacag
      481 cgtgtttttc ttgtactttt gaagattata gagtataatg tatgtgtaga aaattagtat
      541 gcacgctcag ttttcgtgca tattcaatac atggtattgg aggattttaa gatgagtatt
      601 gaaaagatca atcaggcaaa ggctgaaatt gccgcaactt ccgcttataa gacaattacg
      661 gcgttttttg atgcagacag cttttgtgaa attgatgcct ttgcaaaatc cggtgaaggt
      721 tttgccgagg ttgttgcagg ctttggaaca gtagaaggta tgcctgttta tgcgtttgca
      781 cagaacagcg acatttgcgg cggtgccatg agtaaggcac aggctgccaa gcttaaaaag
      841 ctgtatggtc ttgcactcaa gacaggcgct cctgttgtag gtttctatga cagcgttggc
      901 ggcagactta atcagggtac agagcttctc gcaggttgcg gtgatgttct caatgcggct
      961 gcgtcacttt cgggtgttgt accgcagatc tcggttgttc tcggcacttg cctcggaaca
     1021 aatgctctta acgccgcaag cgcagacatt gttatcatga gcaaagacgc acagctttca
     1081 ctttcggtaa caggcaagca ttccgatgcc gcttacaatg ctgaaaacgg tattgcctca
     1141 atcgtttgtg acgatgcaga caaggcaatc aaggctgcaa aggaacttat cctttatctt
     1201 ccgtcaaata acctcacaat ggctcctcag tcatttgaag aagctcccgc agaggacggt
     1261 tgcggttgtg ttgtcagcag aacagttgac ggcaacagca ttgtaaagct cttcaatgat
     1321 tacggcaagg aagcaaatgt tcgttttgca agactcggcg gtcaggttgt aggtattgtt
     1381 gttacaaagg gcaaggagct tggttgcaag tctgcaaaca aggtagcaaa gtttgttcgt
     1441 ttctgcgacg ctttctcact ccctgttgta acattcgtaa actgcccggg ctttgagtca
     1501 atcaagtcgg caacaaaggc atcagccgct tatgctgagg caacaacagt taagatttct
     1561 gttgttacag gaaaggcaat cggttcaggc tatgttgctc ttgcaggcac aggcgctaat
     1621 gcagatgttg tttacgcact tcccgatgca gttatttcac ctgttaatgt tgaggctgcc
     1681 gcattcatta tggctcccga agttatgaat gttgccacag ataagcaggc tgaggttgct
     1741 cagaagtttg ctgacgagaa tctttctgct tacaatgccg ctcagaacgg ctatgttgac
     1801 ggtattgttg aagaagctca gctccgtcag actcttattt ctgctcttga tatgctctcg
     1861 ggcaagcgtg tttcaacact ttcaaagaag cattcaacta tctgataaat gattacttgt
     1921 taaaataaaa ggggatacta aaaatgaaga atttaagaat tacagttaac ggcacagcat
     1981 atgatgttca ggttgaagaa ctcggtggtt cttcagctcc agcagcagcc gctcctgctc
     2041 cggcagccgc tcccgctcct gcagcaaagc cggcagctcc cgcaggcgct cagggttctg
     2101 ttgttgtaaa ggctcctatg cccggtacag ttgttaatgt tgttgtttcg gcaggacagg
     2161 ctgttaaggc tggagatgac ctcgtattca tcgaggctat gaagatggaa actcccgtta
     2221 aggctccgca ggacggcaca gttgcaacgg ttgatgttgc aaagggtgag tctgttgact
     2281 caggtaaggt tctcgtaaca cttaactaat caataattcg gagaaaggga tgctgtaaaa
     2341 tggcaaaaaa aatcagagtt accgaaactg ctctgcgtga cgctcatcag tcactcattg
     2401 caacaagaat gacaacagag gaaatgctcc ctgttcttga caaactcgat aaaatcggtt
     2461 attactcact cgaatgctgg ggcggtgcaa catatgactc atgcctcaga ttcttaaacg
     2521 aagatccgtg ggacagactc cgcacaatca gagagcattg ccctaacaca aagctccaga
     2581 tgcttttcag aggacagaat atgctcggtt atcgtcacta tgccgatgac tgcgttgagt
     2641 accttgttca gcgttcaatc gcaaacggta ttgacattat ccgtattttt gatgctctta
     2701 acgacatcaa gaatcttaaa acagctatca aggccgctaa caaagaaggc ggtcatgcac
     2761 aggttgctat cagctacaca acaggtcctg tattcacaga tgaatactat gttgagtatg
     2821 ctaagagaat tgcagacgca ggtgcagatt caatctgtat caaggatatg gctgctcttc
     2881 ttactccgac aagaaccgaa agccttgtaa aggctatcaa agccgctgtt ccggagcttc
     2941 cgcttcagct ccacacccac tacacatcag gtcttgcatc aatgtgtctt ttaaagggtg
     3001 ttgaggcagg tgctgacggc attgatacag caatcagccc actcgctctc ggtacatcac
     3061 acgcacctac agagtcaatg gttgccgctc tttcaggcac agagttcgac acaggtcttg
     3121 accttaaaca gttctctgac atccgtgctt acttcatgac tctccgtgag aagtacatca
     3181 agtcaggact tcttgatcct aagatgctcg caacagacgc taacgctctt atctatcagg
     3241 ttcccggcgg tatgctttcc aaccttcttt cacagctcaa gcaggccggt aaagaagaca
     3301 agcttgacga agttcttgca gaagtacccc gtgttcgtaa ggattcaggt tatcctccgc
     3361 ttgttactcc gacatcacag attgtcggca cacaggctgt attcaatgta atcacaggca
     3421 agcgctactc aatgtgcaca aacgagttca agggacttgt tgccggtgag tatggtacaa
     3481 ctccaatgcc gattgatcct gcgtttcaga agaagattat cggtgacaag aagattatca
     3541 aaggtcgtcc tgcagatcag cttgagcctg agcttgataa gctccgtggc gagattgagc
     3601 agtggattga acagcctgag gatgttcttt cttatgcaca gttcccgaag gttgccctcg
     3661 acttctttga aaagagaaga aatgccaagg ttggcatcaa cggcgacaag cttgacaaga
     3721 aaaatatggt tcacccagtt tgatttgaca accaaaatta acatttatgc cactttcgct
     3781 atgaaagtgg cattttcatt tgagcagaat tatttttgct aaatttttag caactatatt
     3841 gcattacata tattttagcg gtataatgat gtaaattgaa tatctgttgc gtataccatt
     3901 attacagata gaataaataa aagatgagga aataaaaatg aaaaaacttt taactacatt
     3961 gatagcattt gtaatgtgct tttcggttgt aacaacagct tttgctgcta cacctgatga
     4021 agcttctgat ccagacttga tttcagatat taaacaggct atgttagata catattatgg
     4081 cgatgaaaag cctgatttta ttgaagtaag aatatatggt acagccagtg acggtggcgt
     4141 gtatttcgat tttatggata gttttacaca ctggacagat gaagtggaat tcgatatagg
     4201 tgattatact gtttcttatc cgagagattg tcccgttttg ttatacaaga ataataaagt
     4261 atataccttg tcagatgcct atgaaacagg tgtaattgat gatgatatgc tctatgaatt
     4321 atatgtttgg ggaaatcttt ggggtaagat agatgttacc ccaaagggtg aagatagagc
     4381 tctcctttca gaaataaagc gtgtaattat aaataaatat tacaatggca aagcacctga
     4441 atatttgaat gtcgaaattg ttggttctac aagtgataaa acagtatgtt ttagaaatat
     4501 accctttatg agtttaggcg ttatgattga acaaacaatt ggtgactata cttattatta
     4561 caaccatggc gatgatgtta tgctttataa gaatggcaat gtttactcaa ttaaagaggc
     4621 ttatgaaagc ggagttattg acgatagtat tcttgaagaa ttgtcaaaaa tgaattttgg
     4681 tttggaatct aataaaccga atacaactgt tcctactgag cctacaactt cggttgcaac
     4741 agttgacgaa cctgtaacag tacccgatac aacttcggca actaagcctg tttcaacaag
     4801 cgacacagct acaaatgaca cactgagcaa ttcacagaat aacagcggtg ctgtacagac
     4861 aggacagaac agcgttgctg taattcttct tgttgcaatg cttgcaggtt gtgcagtaat
     4921 ttttgcaaaa cgcagaaatt attttaaata attcaaaata tcaacagaat atataaaata
     4981 aaccgttctc gcttttgtga acggtttatt tattttagct taaaaatttg tgatagttta
     5041 tcaagatgta ttgcttttta tatcatttaa tgttacaatt aacttgcata aaaaaataaa
     5101 cgaattattt tgtaatgcgt agaatttgaa caaagcgagg gatagatatg aaaaagtttt
     5161 tacctatagc catggcggcg gtaatgtcga tgtctgcggt tgcggtttcg gcagtttctg
     5221 caaatgcggt tgaaccgctt aacacacccg tgcagtatgc acaggttgca agggcaagct
     5281 tggcaacacc gaaaatttca aaagccgaaa gcgtttacgg cggtgtaaag cttacatgga
     5341 acaaagtgaa tggtgcggct aagtacagag tttactacaa gggccgtaaa ggctggacac
     5401 gaatggtcga tacaacttca acctcatata tcgacaagga tgtttcatcg ggcaggaatt
     5461 acacctatac tgtaagatgt atttctgctg acggaaagag ctttacaagc ggttatgatt
     5521 caaaggggac aactgtaaaa tatgttgctg cccccgaaat ttcaaagctt gaaaatgtaa
     5581 acggcggtgt gaaaatctct tggggcaaag taagcggtgc aactaaatac agagtttact
     5641 acaagggccg taaaggttgg acacgaatgg tcgatacaac ttcaacatca tatatcgaca
     5701 aggatgtttc atcgggcagg aattacacct atactgtaag atgtatttct gctgacggaa
     5761 agagctttac aagcggttat gattcaaagg ggacaactgt aaaatatgtt gctgcccccg
     5821 aaatttcaaa gcttgaaaat gtaaacggcg gtgtgaaaat tacatggaac aaagtaagcg
     5881 gtgcatcaaa gtatagaatt taccagaaaa attcgtcaga ttggttcaga gtatcagata
     5941 cgacttctaa ttctatagtt gataaatctg ttgatgtggg aacctatact tataccgtga
     6001 ggtgtataag tgatgacgga aagagttttg agagtggatt taacccaaaa ggctcaagta
     6061 tcagatatat tcaagctcct aaaatacttg aaaccaatgt tgtaaacggc ggtattaagg
     6121 tgatttggga ttctgaagaa aatacaaatt acagattgta ctgcaaaaca gaaggtaagg
     6181 gctggacaaa agtatgcgat agcaaaacag gtgttgtgac acataaaaat ttacagccga
     6241 ataagaccta tacatacact gtaagagcaa tcagttccga cgctaaaaag tatttgagcg
     6301 gttatgaccc tgagggaatt agcgcaaaat atgttgccac accgaaaata tcaaaggcag
     6361 aatatacata tgacggtatc aagcttgcgt ggaataaggt tgcaggtgct gaaaaatatc
     6421 gtgtatatta taaggatgct accggttgga ataaacttgt agatacaaaa ggtacaagtt
     6481 atcttgacaa gggacttgtt tcaagagaac tcagcgtaaa agatagttct gtaaacggtc
     6541 agtatattta tactgttcgc tgtatttcaa gtaacggcaa agtttttcag agcggttatg
     6601 acacaaaggg tgtaaaaagt gcattatata acaacggatg tccggaaatt tataatattg
     6661 atacaatgca cggaggaatt accttaaatt gggaggctgc cgctgataaa atttcaaagt
     6721 atcgagttta tattaagcaa aacggttcgt ggaaaaagct tgctgataca acaaataatt
     6781 attacactca taaaaatgta aaagcaggac agacctacac ttatactgta agatgtgtgt
     6841 caaaggacgg taagaaattt acaagtacct ataatccgtc aggtgttgca tttaagtata
     6901 aaacaaccaa caaaacaaga gatgcatata tagattatct gcttaaacat gaatcggagt
     6961 ggttgcctga actcaaggtg ggggacattg ctttggccgg tgtgcagttt acagaccttg
     7021 attttgacgg tgttcctgag cttatagcgc aggaagcagg ggataaggaa tactatttga
     7081 atgcaagggt atatactttc aagaatggaa agctttcatt ggttggattt gataattcta
     7141 tgacctacat tcagaataga ttggcctact tatacgataa atcggctaaa aggtatgtga
     7201 taaattcagc cgagttatca accagcaatc ccgatcgtta tcttgattgt gaaaactata
     7261 cattgagtta tgatggcaac cttataagtg ctcatccgta ttcttcttat catttagctc
     7321 ttgaaaattg gggattggat tacacctatt atgttcatgg caggacaagc aaacaagtgt
     7381 ataatgctgc aaacttgagt acactcgata attgtgtaaa tgcacatatg tacagtcagt
     7441 ttgtttactg ttctgttgac ggttatccaa aactttggaa tcagtttaca accgatcaga
     7501 aaagacagta ccttaccgat tcttacaacg cattttcata tgataaatat tgattcctaa
     7561 aagtaataaa ttataacggt aaagggttca gccgtaaaaa gctgaaccct tttattgcac
     7621 aacaaaaacg gtttagccaa attgactgaa ccgttaattc gtactataca acgctctggt
     7681 tacagaagtt cgacgaataa aaaatattta tgcccgagcg taatatagct accatttgaa
     7741 caattctgta gaggcggata ttatccgccc gctttgatga aatttatgtt gatgctcata
     7801 tgttttgaca taataaaagc cgttctcgtt attgagagcg gtttatttat tttagcttaa
     7861 aaaatttgtg atagtttatc aagatgtatt gctttttata tcatttaatg ttacaattaa
     7921 cttgcataaa aaaataaacg aattattttg taatgcgtag aatttgaaca aagcgaggga
     7981 tagatatgaa aaagttttta cctatagcca tggcggcggt aatgtcgatg tctgcggttg
     8041 cggtttcggc agtttctgca aatgcggttg aaccgcttaa cacacctgtg cagtatgcac
     8101 aggttgcaag ggcaagcctg gctactccga aaatttcaaa agccgaaagc gtttacggcg
     8161 gtgcaaagct tacatggaac aaagtgaacg gtgcggctaa atacagagtt tactacaagg
     8221 gccgtaaagg ttggacacga atggtcgata caacttcaac atcatatatc gacaaggatg
     8281 tttcatcggg caggaattac acctatactg taagatgtat ttctgctgac ggaaagagct
     8341 ttacaagcgg ttatgattca aaggggacaa ctgtaaaata tgttgctgcc cccgaaattt
     8401 caaagcttga aaatgtaaac ggcggtgtga aaatctcttg gggcaaagta agcggtgcga
     8461 ctaaatacag agtttactac aagggcagta aaggctggac acgaatggtc gatacaactt
     8521 caacctcata tatcgacaag gatgtttcat cgggcagaaa ttacacttat actgtaagat
     8581 gtattacatc agacgcaaag aaatttacaa gcggttataa cccgacaggc aagtcggtaa
     8641 agtatgttgc cacaccgaaa atttcaaaac ttgaggttac atatgacggc gtaaagctga
     8701 catggaacaa ggtcgcaggt gcagaaaaat accgtgtgta ctacaaggac aggaacggtt
     8761 ggacaaagct tggcgacaca acaggcacga ctatgcttga tatgaatgtt gtttcaaagg
     8821 aatttgattt aagcgttgat gatatttatt acacggttcg ttgtatcagc aaggatgcca
     8881 agagttttac aagcggctac gattcaaagg gtacgccaat tggcgatcat caggattgtc
     8941 ccgaaattta cagcattggt gcagtaaaca acggtgttga aatgcattgg acgggagatg
     9001 cgccaaagtt ccgtgtttat attaaagaaa acggttcttg gaagaagata gcagaaactt
     9061 atgacaacta ttatgttcac aagggtgcaa ggtccggcag taacacttat acggtaagag
     9121 gtgtttcaaa agacggtaaa aagtttacta cgatgtttaa cccaaccggt gtaacataca
     9181 gatataagac atccgataaa acaagggacg cttatatcaa ttatatgatg aatcatcaga
     9241 gtgaatggat gccaagcttg ggaagtaatc acaatttgtc aggtgttatg tttttggatt
     9301 tcgactttga cggagttccg gagcttgttg cacaaaaggc tgattccaat gagtatagtt
     9361 tccattccgt tgtttacaaa tttgaagacg gtaagttaaa aagagtggga aatgttaacg
     9421 acggttttgc gatatactat aataaaactg ccaaaaagta tgaggttcac gacctaaaga
     9481 tatctttaaa tgtagatgac ggttactatt ggtcgggtaa ttcaataatc acatacgacg
     9541 gagagaatct ttttgcaaat atgtattcgg caagaggtgt aggcgaagaa tcaaataata
     9601 atatttatta taattatttt gacggtaatg acaaaaatat ttcacgggca aaatataacg
     9661 aaattaacct taaacagttt aataattgcg taaatgcaca tatgtttacc caatttattg
     9721 cgacaggtta tggtgataac agcgtatggg gtgagaacac taccgctgag aataagcagt
     9781 ctttgcttga cgcttataat tctttctcct atgagaagta ttgattattt aaaaattaat
     9841 aagttttaac tgcaaaaggg ttcagccgta aaaggctgaa cccttttatt gcacaacaaa
     9901 aaacggttca gccaaattga ctgaaccgtt aattcatact atgtaacgct cgggtgacaa
     9961 aagtttgaat atatcaaact aacttcacaa actaaaaaca ttagttgttg atgagcttat
    10021 cttcgtcaga ccagctgtag agctttctaa cttccttacc gaatacttcg gcaggagctt
    10081 cggcagcgag ctttctcata gccttgaagt gaacctgtga accggcatcg ctcatgtcaa
    10141 ggaggaagtc cttagcaaat gtaccgtcct gaatgtcaga aagaaccttt ctcatagcct
    10201 tcttagtatc ctctgtgatg atctttggac ctgtgatgta gtcaccgtac tcagctgtgt
    10261 tagagattga atatctcatg cctgcaaaac ctgactgata gataaggtca acgatgagct
    10321 tcatctcatg gatacactca aagtaagcgt ttcttgggtc gtaaccggca tcgcaaagtg
    10381 tttcaaaacc tgcctgcata agtgcgcaaa caccgccgca aagaacagcc tgttcaccga
    10441 agaggtctgt ttctgtttct gttctgaatg ttgtttcaag aacacctgct cttgcaccgc
    10501 cgataccgag tgcatatgca agtgcgagat ccttagcctg acctgtagca tcctgctcaa
    10561 cagcaacgag gcaaggtaca cccttaccaa cctgatactc tgaacgaact gtgtgacccg
    10621 gtcccttagg agctaccatt gtaacatcaa catcctttgg aggcttgatg caaccgaagt
    10681 gaatgttaaa gccgtgagcg aacataagca tattgcctgc ttcgaggttt ggctcgatgt
    10741 cgttcttgta aagagctgcc tgcttttcat cgttgataag aatcatgatg atgtcagcct
    10801 gctttgcagc ctctgccgat gtatatacct taaagccctg tgcctcagcc tttgcccagc
    10861 tcttgctgcc tttgtaaaga ccgatgatta catcgcaacc tgaatccttg aggttgagag
    10921 cgtgtgcatg accctggctg ccgtaaccga taatagcaat tttcttaccc ttgagaaggt
    10981 caaggttaca atctgactga tagtagattg gtgctgtcat gttttttgtg tagtctttca
    11041 tattaaagtc ctccttaccg caaacgcggc atataaatta aaatatatgc taactgtaag
    11101 attaaacgga aaccgaagct gtgcctctgt caatggcaac agtacctgtt cttacaatct
    11161 cacggatacc ataaggcttg agtaagtcaa caagcgtgtt gatgcggctt gcacattcgc
    11221 agtactcaac ggtaactgac gaaggggata catcaacgat tttcgcctgc ataatttcaa
    11281 ccgttttgac aatttcggct ctttttgagg cggcgcagtg aactttgatt aaaacaagct
    11341 cacggctgat aaattcgccc tcgttaagcc tttttacctt aatgacggga atgagcttgt
    11401 tgagctgttt ttcaagctgt tcaacaatgt actcgtcacc gtttgcaacg attgtgattc
    11461 gggaaaccga cgggtcctga gtaacaccta ctgcaagtga gtcgatgtta aaacctcggc
    11521 gagagaaaag tcccgaaatt tttgaaagaa cgcccgcctg attttcaaca agtattgata
    11581 atgtatactg cattttatca cctcattaaa ttgacggagt gtcggggtga acatcgcaaa
    11641 caagaatgaa cggtttttcc gaatcaacaa tacccttgat gatgttttcg gcttccttgt
    11701 ttgaatgagc ctctgcatgg tcaatgccgt aagcatcggc aatcttcaag aagtcgggat
    11761 caccgttgag aattgttgcg gagtgtctgc cgccgtagtg tttgtcctga agttcacgaa
    11821 ccattccgag tcgtgcgttt ttcataatga tgattttaat tccgagctga ttgcctgcaa
    11881 tagtcgcaag ctcattaagc cccatctgaa aactgccgtc accgcagatt acaataacat
    11941 cacggtctgg tcttgcaaac tttgcaccga ttgcagcggg aattgagtaa cccattgtac
    12001 ccataccgcc tgttgtgagg aatctgccct cacgaatacg gaagttgttt gcacaccaga
    12061 tttgattttg tcctacatcg gcaacaagaa ttgcctttga gcggaacatt gcgctgagat
    12121 gaccgacaag tgttctcggc tcaacaaagc cgtcaaaaac gggaggctca cggtaaaggt
    12181 cttttttcca gttctttacg gtttcgctcc acattgttgt aaccttgtaa tcgccgatgc
    12241 tgtcaagcag catattgatg acatttttca tatcgcctac aatcggaatt tctgttttaa
    12301 cattcttacc gatttcagca gggtcaatgt caatgtgaat tacctttgtg ttttcactca
    12361 tctggtcggg agccgcaaca gctctgtcac cgagtcttgc accgcatacg attacaaggt
    12421 cggcttcgtg aagagcacgg ttggcaacag ccttgccgtg agtgccgagc attccgagat
    12481 aaagctcatg ctcgctgggc ataacaccga tgcccatcat agttgaaata acggggatac
    12541 ccgtagtttc tgcaaatttt tgaagtttaa gcttgatacc cgaactcagc acgccgccgc
    12601 ctgatacgat aacaggacgc ttgcttgcgt tgatggcctc aacagccttt ttaacctgaa
    12661 ttgcgtgtcc cttagtgttc ggcttgtaac cgataatgtt tacgctttcg ggatattcaa
    12721 aactttcaat ttcattttcc tgaatatcaa cgggaatgtc gataagtaca ggaccgggtc
    12781 tgccggttga ggcaatatgg aaagcctctt tgaaaactct cggaaggtct tctgttttgc
    12841 tgacgagata actgtgcttt acaaacggtt cacaagctcc cgtgatgtca gcttcctgaa
    12901 agacatctct gccgagaagg tcggaacgaa cctgacctgt aatggcaaca atcggaatag
    12961 agtccgtata ggcggttgca atgcctgtga tgaggttggt tgcaccggga ccggaagttg
    13021 ccacgcaaac accgggacga ttactgcatc ttgcatagcc gcttgccgca tgagcagcgt
    13081 tctgttcctg acgaacaaga atgtgggtaa tgctcgagtc gtaaacttta tcgtaaaatg
    13141 ggcaaatagc cgcaccgggg taaccaaaga ctatgtcaac gccctcggct tccaaacatt
    13201 ttaccataat ttcagcaccg ctgatcatta tgttttgtcc ctcctatcct tatttattgt
    13261 gagcaaaagg tgttttgtaa caataaatat acctttttgc tttaccgcta attatacaat
    13321 aaatacctta aaaagtaaag agcagtattg cccataaatt aaattttttg caggatttta
    13381 aattattctg tcatcgcctg aaaaagatat aataaatgat taacaacaaa agcaaaatgc
    13441 tgcccaaaaa agtatctgta taagagtaat aacaagaaaa ttcccgaaca gttttacctg
    13501 ctcgggaaca gtaatgattg ttgaggaaat caatatttct ttttgaggag tcttgcggct
    13561 atgaggacgc agactacgct gacgcctgtg tcggcgataa cggacatcca gatttgtgca
    13621 agaccgaatg cggcgaggat gattacaaga gccttgattg agagggcaaa gatgatgttg
    13681 cccttgacag tgttgataac acttcttgca attttaattg cctttggaag ctgcttgagt
    13741 gtgcctgatg cgagaactgc gtctgacgct tcaatagcgg cttcactgcc gaatcccatt
    13801 gcgataccgc agtcgcttgc cgaaagaaca ggggcatcat tgatgccgtc gcctacaaag
    13861 caagcaccct tggattttga tttcaagccc ttgaaaagct caagcttttg agcagggaga
    13921 agctctgcgt gacattcgga aagtccgagt tcgtttttaa cattttcggc aggctgttgt
    13981 ctgtcgcctg tgagcattac cgtgttcttg acaccgagcg ctttaagctg tgagataacc
    14041 tcttttgcct caggtcttac tgtatcgctg acattgagcg aaccgataag ctgaccgtca
    14101 taaattacga aaacagaatc gtctttattt gcaatcttct tctgttcgtc cgaaagaatc
    14161 tttgaaccgc cgcactgaat agttttgccg ttataaactg cgcttgttcc gtgaccggca
    14221 ctttcgctgt agtcggaaag ctcgggaagt tcaagaccgt ttgccttctc tctgattgcg
    14281 gaggcaatcg gatgagcaga atatttttcg cttgcagcgg caagagcaag aacttcgtca
    14341 gcactgtatg aaccgacagt attaaccttg tttacgctga gcttgccgct tgtgagtgtg
    14401 cctgttttat cgaatacgaa tgtgtctgct tttgcaagag cctcaatata ttttccgccc
    14461 ttgatgagta caccgacttc ggatgcagcg ccgatacccg aatagtagga gagaggtacg
    14521 gaaataacaa tagcacacgg acatgacgct acaagacaaa caagcgcacg gtatagccat
    14581 tcgctgaatg ctccgagtcc gcaaagtgga gggattactg cgattgcagc tgcaatgagt
    14641 acaacaacag gtgtgtaaac agaggcaaat cttgaaataa gcttttcgct gttgcccttt
    14701 tgagcggcgg catcttcaac aagctgaaga attcttgttg cggtactgtc gccgaaatgt
    14761 tttgtggttt tgacggtaat aaggttactg ccgttgattg cgccgctgag tacctcactg
    14821 ccctcgcctg catcaacagg aaggctttcg cctgtgagag ccgatgtgtc gagagttgtt
    14881 ttacctttaa taataatgcc gtcaagcgga actctttcgt atggcttgac ttcaatgata
    14941 cttccgattt caacgctttc ggcaggaaca acctgttccg caccgtcaac aataattgtt
    15001 gctgtatcgg gacgaatgtt tgcaagcttt tcaatgtcac ggcgggatgc gtcaactgct
    15061 cgatcctcaa aaatttcacc gatagaaaag aggattgtta ccattgccgc ctcaacaaaa
    15121 tcgccaagac agaatgccgc aattaccgca acagacataa gcgttgtttc gtcaattctc
    15181 agctttagaa tgttttttgc accattgatg aataccttgt aacccgaaag aagtgttgca
    15241 acaaaacacg ctgcgagtac aacataatga acagccgtaa caccgtcaag tgtaaggtgg
    15301 agaatttcgg acactacagc aagtacaatt gaaattgcaa ggaagattgt gtcacggttg
    15361 attttctttt tcgtgatttc gggttctgcc tttgttgtga tatcattttt cggagttttg
    15421 tcaacaacgg ttacaccgtc ctcaatgctg tcgcaaattg cctgaatttc ggaaacagga
    15481 ttctgctttt cgcttttgaa gttgagaagt tttgtcgcaa aattaaagct tacatcctca
    15541 aagccgtctg tttctgcaat tttagcctca atcttgcctg cacaatgagc acaattgaga
    15601 ttgtctaaag tgtaggtgta ttttttgaga ttggttttcg gagttttgtc aacaacggtt
    15661 acaccgtcct caatgctgtc gcaaattgcc tgaatttcgg aaacaggatt ctgcttttcg
    15721 cttttgaagt tgagaagttt tgtcgcaaaa ttaaagctta catcctcaaa gccgtctgtt
    15781 tctgcaattt tagcctcaat cttgcctgca caatgagcgc agttgagatt gtcaagctga
    15841 tatttgtacc tcatatgtct ccctccttat tcaagaacat ggtcaagtcc catttctatg
    15901 attcgtttca catggtcatc gtcaaggctg taataaatct gctttccttc acggcgaaca
    15961 cgcaccagct tgttctgcct taacacacgc agttggtggg aaattgtgct ttgctccatg
    16021 ctgagagctt cagcaatgtt gagcaccgac atttcatttt ccgaaatggt gtacataatg
    16081 cgaagtcggg ttgaatcacc gaaaacctta aaaaggtctg caagctcaaa cagcacatca
    16141 atgtcgggca tttcgggagt ggttgttttt tctttgtttt ccataggcgt cccctttaat
    16201 tttctctcag gttaatagtt atacttgaac atatgaagat atgctcatat gttaattata
    16261 atatagcatt tcctttttaa aaagtcaata gacacacacg aaaaaatgta atgtttttca
    16321 agtttttttg ccccaaagtt tcacttgttt attgtgtccg tttggaaagt atatatagta
    16381 tagaaagtta attttaaatt tgaaaaaaga agattgaagg tgtaaaatta tcgtaggaat
    16441 aacggaacga tatttttctg tgttcaattt gaattgtaaa atgctcagat gcctgatgat
    16501 aacacgaaaa taacacttgt ttcaatttgt aataatttta caaaaaatcg ctttgattaa
    16561 ttacttcttt ttaggaaaaa acggttttaa aaagcatggt tggttatatt aaaaacaaaa
    16621 aaagcaacaa attaataatt tgagtacaac ttgcccaaaa atagattaca gttttattat
    16681 tccgttgact ttactacaat tttgtagtat cattttctgt aagagaattg ttaaattaca
    16741 tctgcgtaac cgagtgggtt cgtttttaat aaaatgtaac aaattagttc tcattatgaa
    16801 ttttagattc gtataatttt tgatttttac ttatacacta tatagatata cattttcaga
    16861 tatttagctt atttagttaa aagtatcttc tacacattaa ttggggtgta acaattggag
    16921 aagttcgtag ttaccggcgg aaagccatta tcgggtgaag tgacaatcag cggtgcgaaa
    16981 aatgcagccg ttgcaattat tccggcagtt attctttgtg atgaaccgtg ccagattgaa
    17041 aatattccta acatcagcga tgtatcactt atcagcagaa ttcttcagca gatgggtgct
    17101 aatgtaagac gaatcaaccg ttcgtcctta tatattgatc ctacaaaaat ccgcacatgc
    17161 aatgctgtga ccgaccttgt aagaggtatg agagcgtcat attatcttct cggcgcactt
    17221 ttgggcaagt acggcaaggc taaggtggct cttccgggcg gctgtaactt tggcgtgcgt
    17281 ccgattgacc agcatcttaa aggctttgag gctctcggtg cgacaactca gcttgttgac
    17341 ggtgcgatta tagaggcaga atgcgacagc cttgtcggta cacatgtgta ccttgatgtt
    17401 gtgtccgttg gtgcaacaat gaacattatg cttgccgcat caaaggcaaa gggacagacc
    17461 attattgaaa atgccgcaag agaaccgcat attgttgacc ttgcgaactt ccttaattca
    17521 atgggtgcgg atgtcagggg cgcaggtacg gatgttatca aaatccgtgg cgttgagtat
    17581 cttcacggaa ttacttattc gattattccc gaccagattg aggcaggaac atatatgtgt
    17641 gccgccgccg caacaagagg ttgtattacg gtaaagaata ttacaccgaa gcatcttgaa
    17701 tcaatcagcg caaagctgcg tgagatgggt gttaagatta cggaatatga tgaggctctc
    17761 aaggttgatg cgtcatctgc tccgctaaag cgctgtaaca tcaagacaat gccgcatccc
    17821 ggctttccga cagactgtca gccgcagttt gccgcattgc ttatgagcgt tcccggaaca
    17881 agcatcatca acgagaatgt ttgggataat cgctatcagt atgtcagcga gcttatcaga
    17941 atgggtgcgc agatttctgt tgagggcaga cttgcaatca ttgaaggcgg tgttccgctc
    18001 acagcggctc ccgttaaggc aaccgacctt cgtgcaggtg cggctatgat tattgccgct
    18061 cttgaaatta acggtacaac agagatttca aatattcagt tcattgagcg tggatatgaa
    18121 gatgttgttg aaaagttcag aggacttggt gcagatatca aaaaggtgta ttttacagga
    18181 gacaacgagc aggagctcgg tgcctgacta aaatttaatt agaaatcaaa gccgttttct
    18241 tcgtgagaac ggcttttttg tgagataatt tacaaatttt aaaatttgtg ttatcatatt
    18301 cgttacacta aagataagga ttgattgttt tggcaagagc agtaccgctg ttcagcggaa
    18361 gtaagggtaa cagctactac ataggttcgg caagcgaagg cgtactgatt gacgcaggtc
    18421 gttcatgcaa gcagattgaa aatgccatgc ttgcaaacgg acttgatatg ggcagtatcg
    18481 gggcggtttt tataactcac gaacacactg accattgcag tgcgttgcgt gtgcttgcaa
    18541 agcgttacgg ctttaaggtg tattcaagcc ttggtacgct caatgctttg agggcaggta
    18601 ataagcttga tccaaacacg gatgcagatg ttataactga cgaggttgta atcggcaata
    18661 tgcgtgttca gcgaattgac accccccacg atgcggcgga aagctgttgc taccgtgtta
    18721 ctgctcctga cggaaaatcc gcacttatag caaccgatat gggcgttatg ttgcccgatg
    18781 tcagaactgc cgcagagcag agcgactttg ttgtgcttga gtcaaatcac gatatcaata
    18841 tgctcaaaaa cggattttat ccttatccgc taaagcagag aatcctttca aacagaggac
    18901 atctttcaaa tgaggcgtgt gcaaaagaac ttgttaacct tgttgaaaag ggaactttaa
    18961 gacttatgct cggccatctc agcgaagaaa ataataccgt tccgcttgca atgtcaacat
    19021 ccgtagacct gctcacatca aacggaatga agtacaaaag cgattattcg cttgatgttg
    19081 ctccgagtgt aagcacaaca aaagccatca tcttttaacc ttaaacaaac aagaggaata
    19141 tgattaagat taacataatt tgtatcggca aaatcaagga aaaatatttt accgacgcaa
    19201 ttgcagagta tgcaaaacgc ttgaccgcat tttgtaaatt caatattatt gagctttcgg
    19261 aagaacgcat taagagcaac ataccgaata ggtcgcagat tgatgaggtt attttctctg
    19321 agggaaaacg aatcatgcaa aaaatttcgc cttcggatta tgttgttgcc atgtgtattg
    19381 agggaaagtc tatgtcgagt gaggagcttt caaagctgat tgacaatgcg tccgtaagcg
    19441 gaaaaagcac cgttgatttt attatcggcg gcagctacgg gcttgacgaa tcggttaaaa
    19501 aacgggcgga tgtccgtctt tcaatgagca gaatgacctt ccctcaccaa atggcaagaa
    19561 tgattttaag cgaacagatt taccgtgcgt ttgagatttc atcaaacggt aaatatcaca
    19621 aataatttac ggagttacta tggcgcttga cggaattttt ttaagacata ttaaaagtga
    19681 aatagaaaaa gaggctctcg gtgcaagggt gtcgcagatt tatcagccga acagagaaga
    19741 gcttgtgttc gggttgagaa cattttccgg caataaaaag ctgttgcttt ctgcacgagc
    19801 aaattcaccg agagtgaact tttgttcctc aacacccgaa aatcctgcac aacctccgat
    19861 gttctgtatg cttttgcgaa aaagaatcgg cggcggaaag cttgtgggac ttcgccagaa
    19921 cggttgcgac cgtgttctta tgctcgattt cgagtgcgtg aacgaactcg gcgatactgt
    19981 gatgataact gttgtatgcg aaattatggg tatgtacagc aacataatta ttgtcgattc
    20041 aaacggcgtc atcatcgatt cactcaagcg tgtagatctt acaatgagca gtaaaagact
    20101 tgtactgccg aatataaaat acgaacttcc cgaatcgcag aacaagctga atctgcttaa
    20161 atgttcggtg cttgatgtgt gtacagccgt aaaaaatctt gacacggaaa tgccgcttaa
    20221 caaggcgctg ttaaggacaa ttgagggcgt ttctccgatt gtatgccgtg agattgaata
    20281 caaggttatg gagggcgcaa caaacagaat tgagggtgtg ctttttgacc gactcgcagt
    20341 tgaaatcaaa aagctgaaaa gcgtttgcag cgattgttcg ggcaagcctg ttgtggttta
    20401 tcgtgaggac ggtaagccta tggacttctg ctttatgaat gttgagcagt acggcgattt
    20461 tgcaaaggtt gagagtgagg aaagcttctc cgatttgctt gacggattct atgaagctcg
    20521 tgacagtcgt gacagaatga gggtgaaatc acaaagcctt acaaagcttt tgaacaacac
    20581 acttgaaagg cttgcacgaa aaattgcaaa gcagaagagt gagcttgaac gctgtgcaga
    20641 ccgtgagcat cttcgcatat gcggtgacct tttacaggca aatatctatc gcattgagcg
    20701 tggtgcggag tatgttgatg ttgaaaactt ttacgatgag aacaacgcaa ttttacgcat
    20761 aaagcttaat ccggcaatct caccttcggc aaatgctcag aagtattaca aggattaccg
    20821 caaggctaaa aatgccgaaa ttatgctcaa agaacagctt gaaaagggta gggaagagct
    20881 tgattatatt aactcggttc tcgatacggt tgaccgtgcg gagaatgaaa aagaccttgc
    20941 acaaattcgt gaggaactta ccgagcaggg ctatctcaag gttcaaaaag gcaaaaagcc
    21001 ccgtcagaca actttgccgc cgctcgaatt tgaatcaagc gacggtttta aaatccttgt
    21061 aggaagaaac aaccgtcaga atgataagct gactttgaaa acagcgtcaa agaacgatat
    21121 gtggctgcac acaaaggaca ttcacggttc tcatgtaatt gttgtttcgg acggcaaaga
    21181 gatttccgac acggcaatct atgaggcggc acggcttgcg gcatatcaca gtaaggcgag
    21241 aaacagcagt caggttcctg ttgactgcac acttgttcgc tatgtgtcaa agccaaacgg
    21301 ctcaaaaccg ggtatggtaa tttatgtcaa caacaaaacc ctgtatgtaa aaccgtcaca
    21361 aacggttgaa aagcagtaag atattttaat aaaaattaaa cggagggcaa gacgctctcc
    21421 gtttttatgt taatttaatt gtttttaacg ggcggtaaaa tcgaatgtaa aaattcgtat
    21481 tttaggggtg cagaatttga actcataccc ttcaaaattt gcacctgccc ccttcagaat
    21541 ttgaacccgt ccccttcaga ttttgaaggg gactacttca aaatttgaag cctaataata
    21601 cccatagaaa aagactaaga gaataatacc aagtaaacaa taccaattga aaaatgaaga
    21661 ggaattcaga tgaccgaact gacaaaatta tccttcaaaa tcccattcgg ggacatagct
    21721 ttcatctgcg gaagaaagct cctgtgtaaa gccgtcaatt cccagtcgca tcatttcaag
    21781 ctttaccttg tcatattctc tgcgtgtgat tttacggtta attcgtgaaa actccctgtc
    21841 gctgaccttg cccataggaa tgtactgaca cataagactt aacaaaacct gatcgccgaa
    21901 tctgcgtttt acaatatcaa gcacttcaag actgttcttt gtgtgggcag gcaaaatcag
    21961 atgccttacg ataacgccct ttttcataat gccgtcatcg tcaaactgag gcagaccaac
    22021 ctgaaaagtc atttcgtgaa ttgcggcaac agccgtgttg acataattcg gtgcggaaga
    22081 gtattttacc gcaagaaaat catctgcata tttaaagtcg ggaagataaa tgtcaacaag
    22141 tccgtcaagc atactgagag ttttcggact tgtgtatccg ctgcagttat atacaatcgg
    22201 aattctcggt ttgtaaattt caagactttt aacaacagcg tgtgcaaaat ggtcagccgt
    22261 tacaaggttg atgttatgca ctcccttgtc ctcaagttct ttgtaacatt cggcaagtct
    22321 ttcgggagtg attgttcttc cgccgtcctc gtttgaaatt tcgtagttct ggcagtacac
    22381 gcatctcatt gtacagcccg aaaagaaaac ggttccgctg ccctttgtgc cgcttatgca
    22441 cggttcttcg ccatagtgcg gagcaactct tgcaacaacg ggcagttctc ccattttaca
    22501 aaatccgttt ccgctgtggg cagtacgaac cgcaccgcat tttctcggac ataaattgca
    22561 aatcatgata tcaccttatt gtctgatata taatgtctga tagaacatta aacactattg
    22621 taccacgatt atgacaaaag ttaaagcctt tgcaaattaa agtgtgaaat ctgtaagata
    22681 atcttcgatg atatcgtcaa gctggcagag ttcaagctca agttcgttgc acatttcgac
    22741 aagctccgtc atttcacgaa agctttcgct gattcccgac acggatttta taagcttttt
    22801 gccgcaaaaa gcgcttatcc caaaggtgtt aaacccgtct tcgggtgtat gattcaatat
    22861 gtaggttatc attttttccc tccggatgac aaccggtcac aatataataa tactattatg
    22921 ttgcaatatt gtcaatatta ttacaaaaat attgttaagt tgtaaacaaa tggtgatgta
    22981 tcagtaataa attgtacata atgacaaatg aatgtaaacc acagttaaag aattatataa
    23041 caataaaaac tttagttcga taaaatctta ataatatgta acaaagtatt acatatggta
    23101 tataatttca gtgcagtcag atttttcggc aaacggcaaa taacatatcg acgacagtta
    23161 actgctgaaa tattgcaata acaatagtta atcattgctc tgcgtcagtc tttatttgtg
    23221 cataatgt
//
