LOCUS       c00007_gnlPro..        13809 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LDBCMDFM_7.
ACCESSION   c00007_gnlPro..
VERSION     c00007_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 19:33:53
            Original ID  :: gnl|Prokka|LDBCMDFM_7
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 89024
            Orig. end    :: 102833
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13809
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[99024:102538]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13514
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..13809
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13809
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             267..1403
                     /locus_tag="ctg7_62"
                     /transl_table=11
                     /translation="MAITIKKVSTKRELKKFIRFNYRMYKGNPYSVPDLYDDMLNTFNK
                     KKNAAFEFCEADYFLAYRDDKIVGRVAAIINNQANKKWECKNVRFGWIDFIDDPEVSSA
                     LIKTVEEWGKERGMTHIAGPLGFTDFDAEGMLIEGFDQLSTMATIYNYPYYPIHMEKLG
                     FEKDADWVEYKIYIPDAIPDKHKRISELIQRKYNLKIKKYTSGRKIAKDYGQKIFELMN
                     EAYSPLYGYSPLTQRQIDQYVKMYLPILDLRMVTLITDANDELVCVGISMPSLAEALQK
                     SNGRLLPLGWFYLLKALFMKRRAKMLDLLLVAVKPEYQNKGVNALLFSDLIPVYQKLGF
                     IFAESNPELELNGKVQAQWDYFETQQHKRRRAFIKEIK"
     CDS             1414..3291
                     /locus_tag="ctg7_63"
                     /transl_table=11
                     /translation="MEENELIPVDNNNAVEYTDDNIRHLSDMEHVRTRPGMYIGRLGDG
                     AHAEDGIYVLLKEVIDNSIDEFKMQAGKKIEITVEENLRVSVRDYGRGIPQGKLIEAVS
                     MLNTGGKYDSKAFKKSVGLNGVGVKAVNALSSRFEVRSYRDGKVRIATFSKGNLLTDET
                     KNTEEENGTYIFFEPDNTLFLNYCFKPEFIETMLRNYTYLNTGLAIIYNGHRILSRNGL
                     VDLLNDNMTATGLYPIIHLKGEDIEIAFTHTGQYGEEYYSFVNGQHTTQGGTHQSAFKE
                     HIARTIKEFFNKNMDYTDIRNGLVAAIAVNVEEPIFESQTKTKLGSTNMVPGGVTVNKY
                     VGDFIKQEVDNFLHKNADIAEAIQQKIQESEKERKAIAGVTKLARERAKKANLHNRKLR
                     DCRIHLNDPKGKGLEEDSCIFITEGDSASGSITKSRDVNTQAVFSLRGKPLNSFGLTKK
                     VVYENEEFNLLQAALNIEDGIEGLRYNKVIVATDADVDGMHIRLLLITFFLQFFPDLIK
                     KGHVYILQTPLFRVRNKKKTNYCYSEEERINAINELGPNPEITRFKGLGEISPDEFKHF
                     IGKDMRLEQVTLRKTDAVKELLEFYMGKNTMERQNFIIDNLVIEEDLAS"
     CDS             3288..3743
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CTP_transf_like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg7_64"
                     /sec_met_domain="CTP_transf_like (E-value: 1e-20, bitscore:
                     66.7, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKAIFPGTFDPFTIGHYSVVERALTFMDEIVIGIGINENKNTYF
                     PIEKREEMIRELYKDEPRIKVMSYDCLTIDFAQEVGARFIVRGIRTVKDFEYEETIADI
                     NRKLAGIETILLFTEPELTCVSSTIVRELLTYNKDISQFIPKGMRIS"
     CDS             3827..5410
                     /locus_tag="ctg7_65"
                     /transl_table=11
                     /translation="MNKIKIYVLLACLWAVSALQAQNFGSEAMRKLQMAEFAISHFYVD
                     KVDEDKLVEEAIIKMLAQLDPHSTYSDAEEVKKMNEPLQGNFEGIGVQFQMIEDTLLVV
                     QPVSNGPSEKVGILAGDRIVAVNDSAIAGVKMSTEDIMKRLRGPKGSKVNLTIVRRGVQ
                     DPLLFTVKRDKIPILSLDASYMIQPKTGYIRINRFGATTAEEFKKAMTSLQKQGMKDLI
                     LDLQGNGGGYLNAAIDLANEFLGQKELIVYTEGRTAKRSDFYAKGNGDFRNGRLIILVD
                     EYTASASEIVSGAVQDWDRGIIVGRRSFGKGLVQRPIDLPDGSMIRLTIARYYTPSGRS
                     IQKPYDSTVDYNKDLIERFNHGELMNADSIHFPDSLKVQTKKLGRTVYGGGGIMPDYFV
                     PIDTTLYTDYHRNLVAKGAVIKFTMQFIEGHRKELKNKYKKFESFDEKFVVDDNMLATL
                     KEIGEKEGVKFNEEQYQKSLPLIKTQLKALIARDLWDMNEYFRVMNTTNESIQKALEIL
                     NSDEYQKKLK"
     CDS             6101..6739
                     /locus_tag="ctg7_66"
                     /transl_table=11
                     /translation="MAIQFELYKTPRPKDEEDKEVYHARVVNFQHIDTDYLAKEIQIAT
                     SLTEGDVKSVLESLSHFMGDRLREGQSVHLDGIGYFQIKLNSQEPITSPKLKANQIKLK
                     ANISFKADAKLKRSVSVVHVERSKLKPHSAVLSNDEIDKLLTNYFKSNPVLTRRDFQGL
                     CGFAPTTAARQIKRLKEEEKKLKNINTYYNPIYVPMPGYYGKAEIKTDE"
     CDS             6767..6910
                     /locus_tag="ctg7_67"
                     /transl_table=11
                     /translation="MKSEEIKELFKQFESIVCEYNKVECWSARELYPLLGYSQWRNFLS
                     II"
     CDS             6977..7555
                     /locus_tag="ctg7_68"
                     /transl_table=11
                     /translation="MVILGSGAEREVDNIFLTRYACYLVAQNGDSRKQEIAFAQNYFAI
                     QTRRAELVEQRLIEYERVQARTKLAETEKLLSGVLYERGVDNQGFAIIRSKGDKALFHM
                     DTKMLKRKLDVPDSRPLADFLPTISIKAKDFAAEMTSVNVQQKDLYGQTAIENEHVDNN
                     VAVRDMLVGRGIFPEQIPANEDIAAGVFL"
     CDS             complement(7684..8646)
                     /locus_tag="ctg7_69"
                     /transl_table=11
                     /translation="MLMLRKIVFFLFVFVGLSLFAQQDYMVSSYVRGNFYNRGRISTES
                     LRASNDLIFLNVHPNKDGSLSFENPRVFQGKGVTTWEGLIKSVRAKVKGTKVKIRLGAS
                     SGEWKAMVADEAARTTFAKNIKTVLEKNKLDGIDLDFEWAENEKEYKDYSLAILKMREV
                     LGDKYLFSVSLHPVCYKISKEAIEAVDFISLQCYGPSPVRFPIEKYCSDIQMVLEYGIP
                     KEKLVAGVPFYGVTKDNSKKTEAYFNFVQNGLVTSPAQNEVIYQGDTYVFDGQDNIRIK
                     TRYAKEQKLKGMMSWDLATDLPLSDSRSLLKTMTEELRE"
     CDS             8920..9789
                     /locus_tag="ctg7_70"
                     /transl_table=11
                     /translation="MPGDSFCIQYTNCTGCPKNVENILVYRNLPKGEHIPKDKCTQNCM
                     LFMIKGELLINSEEHPGITLRERQIVLQAIGSKVEILALTDVEYVVYWFNELPLLCEDR
                     YREMMEQAEAPLTYTPLIMSERLYHLVTSMPEFLAEENPCSKYIDLKCKELVFLITNFY
                     PLPQLGSFFYPISTYTESFHYFVMQNYSNVKNVEEFAHLGGYTTTTFRRLFKNLYGVPV
                     YEWILEKKREGILEDLQHTKMRITEICNRYGFDSLSHFAHFCKDSFGDTPRALRKKAAG
                     GEKIGKVQ"
     CDS             10001..10705
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg7_71"
                     /sec_met_domain="SucD_FumR (E-value: 4.2e-131, bitscore:
                     426.6, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLSNSSVGRKVVMSVTGIALVLFLTFHMAMNLVAIISADGYNMI
                     CEFLGANWYALVATAGLAALFVIHIIYAFWLTMQNRKARGSERYAVVDKPKTVEWASQN
                     MLVLGLIVIVGLGLHLFNFWAKMQLPELMHNMGMHADTLTLAYAANGAYHIQQTFSSPV
                     YVVLYLVWLFALWFHLTHGFWSSMQSLGWNNKVWINRWKCISNIYSTIVVLGFALVVVV
                     FFVKTLICGGAC"
     CDS             10743..12722
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 202.6; E-value:
                     3.8e-62)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg7_72"
                     /sec_met_domain="FAD_binding_2 (E-value: 4.5e-62, bitscore:
                     202.6, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 6e-37, bitscore:
                     118.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKIDSKIPEGPVAEKWTNYKAHQKLVNPANKRRLDIIVVGTGLA
                     GASAAASLGEMGFRVFNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTVKG
                     GDYRAREANVYRLAEVSNAIIDQCVAQGVPFAREYGGTLDNRSFGGAQVSRTFYAKGQT
                     GQQLLLGAYSALSRQVNVGTVKLYTRYEMQDVVIVDGRARGIIAKNLVTGELERFAAHA
                     VVIATGGYGNAYFLSTNAMGCNCTAAISCYRKGAVFANPAYVQIHPTCIPVHGDKQSKL
                     TLMSESLRNDGRIWVPKKKEDAVKLQKGEIKGSDIPEEDRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNNTGLAVFLDFSEAINRLGIDVVLQRYGNLFDMYEEITDVNPGE
                     LAKEINGVKYYNPMMIYPAIHYTMGGIWVDYELQTTIKGLFAIGECNFSDHGANRLGAS
                     ALMQGLADGYFVLPYTIQNYLADQITVPRFSTDLPEFAEAEKAVQAKIDKFMSIQGKES
                     VDSIHKKLGHVMWEYVGMGRTAEGLKKGIAELKEIRKEFETNLFIPGSKEGMNVELDKA
                     IRLYDFITMGELVAYDALNRNESCGGHFREEYQTEEGEAKRDDENFFYVACWEYQGDDE
                     KAPVLHKEPLVYEAIKVQTRNYKS"
     CDS             12759..13514
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg7_73"
                     /sec_met_domain="Fer4_7 (E-value: 5.3e-12, bitscore: 38.5,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_3 (E-value: 3.8e-25, bitscore: 80.3,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.4e-06, bitscore: 20.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKNISFTLKVWRQAGPKAKGAFETYQMKDIPGDTSFLEMLDILN
                     EQLISERKEPVVFDHDCREGICGMCSLYINGHPHGPATGATTCQIYMRRFNDGDTITVE
                     PWRSAGFPVIKDLMVDRTAYDKIMQAGGYVSVRTGAPQDANAILIAKPIADEAMDAASC
                     IGCGACVAACKNGSAMLFVSAKVSQLNLLPQGKPEALRRAKAMLSKMDELGFGNCTNTR
                     ACEAECPKNISISNIARLNRDFIIAKLKD"
ORIGIN
        1 tgcttgggga gataatcccg atgatgctaa cttatacaat gcagccggtt tacctgcttc
       61 tccattcgaa ggacacatca gcctataaac ggcatacgaa aaatagaaaa agaataccgg
      121 aaatgaatgt attatcatca tttccggtat tcttcatatt tacagtccac tccctaatcg
      181 tccagagact atattttctc tttctagcgc gttgtaattt aaagattatc acgtatcttt
      241 gcctcctcaa atcataaata cgagatatgg ctattacaat caagaaagtc tccacaaaga
      301 gagagcttaa gaaatttatc cgtttcaatt acagaatgta caagggcaac ccttactctg
      361 tgcctgacct ctatgacgac atgctcaaca ccttcaacaa gaagaaaaat gcagcattcg
      421 aattctgtga agctgattat ttcctcgcat atcgggacga taaaatagta ggacgtgtag
      481 ctgcaattat caataaccag gcaaacaaga agtgggaatg taaaaacgtt cgtttcggat
      541 ggatagactt catcgacgat cccgaagtat catccgcact tatcaaaaca gtggaagaat
      601 ggggaaaaga acggggtatg actcatattg ccggtcctct cggatttact gatttcgatg
      661 cggaaggaat gctgatcgaa ggattcgacc agcttagcac catggccact atctacaact
      721 acccgtacta tccaatacac atggaaaaac tgggcttcga gaaagatgcc gactgggtgg
      781 aatacaaaat ctacataccg gatgctattc ccgacaaaca taagcgtatc tccgaactga
      841 tccaacgaaa atacaacctt aagataaaga aatatacttc cggaagaaag atagccaaag
      901 actatggaca gaagattttc gaactgatga acgaagcata tagtccactt tatggttatt
      961 ctccgctgac acagcggcaa atcgaccaat acgtgaaaat gtatctgccg atccttgact
     1021 tacggatggt tacactgatt actgatgcca atgatgaact agtctgtgta ggtatctcta
     1081 tgccatctct cgctgaagct ttacagaaat caaacggacg tctgttgccg ctcggatggt
     1141 tctatctgtt aaaggcatta ttcatgaaac gtcgtgccaa aatgcttgat ctgctactcg
     1201 ttgcagtgaa accggaatat caaaataaag gtgttaacgc tttgttattt tccgatttaa
     1261 ttccagttta tcaaaaatta ggttttatct ttgcggaaag caaccccgaa ctggaactga
     1321 atggaaaagt tcaggcacaa tgggattact ttgagactca acaacataag cgccgccgtg
     1381 cgttcatcaa agagataaaa taaaaaaaca gctatggaag agaacgaatt gatacctgta
     1441 gacaacaaca atgcagtaga gtacactgac gacaacatcc gccacttgag tgacatggaa
     1501 catgtacgca cacgccccgg tatgtatatc ggaaggctgg gcgacggtgc acatgccgaa
     1561 gatggaatct atgtcctcct gaaagaagta attgacaaca gtattgacga gttcaaaatg
     1621 caagccggta agaaaatcga gattaccgtt gaagaaaacc ttcgtgtcag tgtacgcgac
     1681 tacggacgag gcatcccaca gggaaaactc atcgaggctg tcagcatgct gaataccggt
     1741 ggtaaatacg acagcaaggc atttaagaaa agtgtcggac tgaatggtgt cggtgtgaaa
     1801 gccgtcaacg ctttaagctc ccgtttcgag gtacgcagtt accgcgacgg caaagtgcgt
     1861 atcgccactt tctcaaaagg aaacttactg accgatgaga caaagaatac cgaagaagaa
     1921 aacggaactt acatcttctt tgaaccggat aatacactat tcctgaatta ctgtttcaag
     1981 cccgaattta ttgagacaat gctacgtaac tacacgtatc tcaatacggg gcttgctatc
     2041 atctataacg gacaccgtat cttgtcgcgc aacggtctgg tagacctttt gaacgacaac
     2101 atgacggcaa ccgggcttta cccgatcatc cacctgaaag gggaagacat cgaaatcgcc
     2161 ttcacgcata ccggacaata cggagaagaa tattattctt tcgtcaacgg tcagcatact
     2221 acccaaggtg gtacgcatca aagtgccttc aaagaacaca ttgcccgtac catcaaagag
     2281 ttcttcaaca agaacatgga ctacaccgat atccgtaatg gattggttgc cgccattgcc
     2341 gtcaatgtgg aagaaccgat cttcgaaagt cagacgaaaa ctaaactggg ttctaccaat
     2401 atggttcccg gtggcgtaac ggtcaataag tatgtaggcg actttatcaa acaggaagtg
     2461 gacaacttcc tgcacaagaa tgcggacata gccgaagcaa ttcaacaaaa gatacaagaa
     2521 tctgaaaagg agcgtaaagc cattgcaggg gtaacgaaac ttgcccgtga acgtgccaag
     2581 aaagccaacc tgcacaaccg caaactacgt gactgccgca tacacctcaa cgatccgaaa
     2641 ggcaaaggac tggaggaaga ctcctgcatc tttatcaccg agggagactc tgcaagcggt
     2701 tccatcacca aaagtcgtga tgtcaacacc caagcagtat tcagtctccg tggtaaacca
     2761 ttgaactctt tcggactgac caaaaaagtg gtttacgaga acgaggaatt caacctgctt
     2821 caagcagccc tgaatataga agatggtatt gaaggattac gctacaacaa agtaatcgta
     2881 gcaaccgatg ccgatgtgga cggtatgcac atccgcctgt tgctgattac tttcttcctg
     2941 caattcttcc ctgatctcat caagaaagga catgtatata tcctgcagac gcctttgttc
     3001 cgtgtacgca acaagaaaaa gacaaattac tgctacagcg aggaagaacg catcaatgct
     3061 atcaatgaac taggaccgaa tccggagatc acccgattta aaggtttggg agaaatctca
     3121 ccggatgagt tcaaacattt cattggtaaa gatatgcgtc tggagcaggt gacactgcgc
     3181 aaaacggatg cggtaaaaga actactcgaa ttctacatgg gcaaaaatac catggaacga
     3241 cagaacttta ttatagacaa tctggttata gaagaagact tggcatcatg agaaaagcaa
     3301 tattcccggg tacttttgac cccttcacca tcggacatta ttcggtagtg gaacgtgcac
     3361 tcacctttat ggacgaaatc gtgataggaa tcggtatcaa tgagaacaag aatacatact
     3421 ttcccattga gaaaagagag gaaatgattc gggagcttta caaggatgag cctcgtataa
     3481 aagtgatgtc ctacgactgt ctgaccattg attttgcgca ggaagtaggg gccaggttta
     3541 ttgtccgcgg tatccgtaca gtgaaagatt tcgagtatga agaaacgatt gcggacatca
     3601 accgcaaact ggcaggcatt gaaaccatcc tgctcttcac agaaccggaa ctgacttgcg
     3661 tcagctcgac gattgtacgc gaattattga cttataataa agatatcagc cagtttattc
     3721 ccaaaggaat gaggataagt tgaaagttga gaatggagag ttgagaagga tgcaggcgta
     3781 tctgtacccg gttgttaata ctcggctatt aatataaagt aagattatga ataagattaa
     3841 aatatacgtc cttttggctt gcctgtgggc agtatcagcc ttacaggccc aaaatttcgg
     3901 ttctgaagcc atgcgcaagc tacaaatggc agagttcgca atctcccatt tctatgtaga
     3961 caaagtagat gaagacaagt tggtggaaga agccatcatc aagatgctgg cacaactcga
     4021 cccgcactct acttactcgg acgcagaaga agtgaagaaa atgaacgaac ctcttcaagg
     4081 taacttcgaa ggtattggag ttcagtttca gatgattgaa gataccctgt tagtagtgca
     4141 acccgtcagc aacggacctt ccgaaaaagt cggcatcctt gccggtgacc gtattgttgc
     4201 ggtcaatgac agcgccattg ccggagtgaa aatgagtacg gaagatatta tgaagcgtct
     4261 tcgtggtccg aaaggttcta aagtcaacct gactatcgtt cgtcgtggcg tgcaagatcc
     4321 tttattgttc acagtgaaaa gagataaaat acctatcctt agcctcgatg cttcttacat
     4381 gattcagcct aaaacaggtt atatccgcat caaccgcttc ggagcaacca ctgccgaaga
     4441 attcaagaaa gcaatgacaa gccttcagaa acaaggtatg aaggacctga ttctcgacct
     4501 gcaaggaaac ggaggaggtt acctgaatgc agccatcgac cttgccaacg aattcctggg
     4561 gcaaaaagaa ttgattgtct acacggaagg acggactgcc aaacgcagtg atttctacgc
     4621 caaaggaaac ggagatttcc gtaatggacg ccttatcatc ctggtagatg aatatacggc
     4681 ttccgccagc gaaattgtca gcggtgcagt gcaggattgg gatagaggaa ttatcgtagg
     4741 acgccgttct ttcggcaaag gattggtgca acgtcctatc gacctgccgg acggttccat
     4801 gattcgtttg actattgcgc gctattatac tccatcggga cgttccatcc agaaaccgta
     4861 cgacagtact gtcgattaca acaaggatct gatagaacgt ttcaaccacg gtgaactgat
     4921 gaatgctgac agtattcact tcccggattc actgaaagta caaaccaaga agctaggacg
     4981 cactgtttat ggcggagggg gtatcatgcc ggattatttc gtacctatcg atactactct
     5041 ttatacggat tatcaccgta atctggtggc taaaggagct gtgattaaat tcaccatgca
     5101 gtttatcgaa gggcaccgga aagagttgaa aaacaaatac aagaaattcg aatcgtttga
     5161 tgagaagttc gtcgttgatg ataatatgct cgccacttta aaagaaatag gagagaaaga
     5221 aggagtgaaa tttaatgaag aacaatatca gaagtcgctc cctctcatca aaacacagct
     5281 taaagcactg atagcccgtg acctttggga tatgaacgaa tatttccggg taatgaatac
     5341 caccaatgag agtatacaaa aggcgctgga gatactgaat tcggatgagt atcagaagaa
     5401 gctgaaataa ggtattcagt aaacaatcat aagacatcat ttttcagttc ggtggacata
     5461 tatactcact atagtgaaaa aatatctatc ataagtatca ttcattttga tactcttctc
     5521 attatcaaag aaataagtat gacagatagc ttttaaaaaa ggtatctatc atacttttac
     5581 cagcaaaaac aggttatcta tcatctacaa aatagccgaa taaaggccct atatgcataa
     5641 gatagcttgt ttttgttgaa tagtttaatt ctcccctgcc ctatatctat cagatagaac
     5701 aaggcgtata aatacctcaa acaagcagag atagtttgct tttctccctg atatagttta
     5761 tctttgttac cgatatagtt cattcttcat ggccgtggcg aattcctacc acggccgtgg
     5821 aaagatacta ccacagccat gaagagatct ctccacggcc gtgggaaact aatgataaag
     5881 gcaccggaag acaactatcc ctatgcctta gtccaagaat aaaggcagga taacttataa
     5941 aagccgcttg ataacaaaca aacaacagct atataacacc ctccccctaa gtccgaagat
     6001 gatcgattag ctttgcaaca acagaaaaca atgtccttat aggcttgcaa cggtaaatta
     6061 aaggtacgta gtaatgtata aggcaaaaaa caaataaata atggcaatac aatttgaatt
     6121 gtacaagact ccccgtccca aggatgagga agacaaagaa gtgtatcacg cacgtgtagt
     6181 caacttccaa cacattgaca cagactattt ggcaaaagaa atccagatag caacttctct
     6241 aactgaaggg gatgtaaagt cagttctcga atccctaagt cattttatgg gggatcgtct
     6301 tcgggaagga caaagcgtcc atctggatgg catcggttat ttccagataa agctgaatag
     6361 tcaagaacct atcacttcgc ccaaactaaa agcgaatcag ataaaactca aagccaatat
     6421 cagctttaaa gcggatgcca aactaaaaag gtcagtcagt gttgttcatg tggagcgaag
     6481 taaactgaaa ccccattcgg ctgtcctttc aaatgacgag atagacaaat tgctgacaaa
     6541 ctacttcaag agcaaccctg tattaacccg tcgcgacttt caaggattgt gcggctttgc
     6601 ccctaccact gccgcacggc aaatcaaacg gctgaaagag gaggagaaga agttgaagaa
     6661 tatcaatact tattataatc cgatttatgt gccgatgcca ggatattatg gcaaggcaga
     6721 gataaagaca gatgaataaa aggaaccaac ataatacaga aataaaatga aatcagaaga
     6781 aataaaagag ctatttaagc agtttgagag cattgtttgc gaatacaaca aagtggaatg
     6841 ttggagtgcg agagaacttt atccattgtt aggatattct caatggcgta acttcctgtc
     6901 tatcatatag aaagcaaaag atacatgtaa aaatgccgga gaaaatattg cataccattt
     6961 tgctgacgtc agcaaaatgg ttatattagg ttcaggcgct gaaagagaag tagataacat
     7021 ctttctgacc cgttatgcct gctatctggt agcacaaaat ggagattctc gaaagcaaga
     7081 aattgccttt gctcaaaact actttgcaat acaaacgcgc cgtgcagaat tagtagagca
     7141 acgtttaata gaatatgaac gtgtccaagc acgtaccaaa ctagccgaga cagagaaact
     7201 tctctcgggt gttttatatg aaagaggagt tgacaatcaa ggattcgcca ttatacgttc
     7261 caaaggagat aaagcactgt ttcacatgga caccaaaatg ctaaaacgta aacttgacgt
     7321 acctgatagt cgaccattgg ctgattttct tccgaccatc agcataaaag ccaaagactt
     7381 tgccgcagaa atgacctctg tgaatgttca gcaaaaagac ctatacggac aaactgccat
     7441 tgaaaatgaa catgttgaca ataatgtcgc agtcagagat atgcttgttg gtagaggcat
     7501 atttcctgaa caaattcctg caaatgaaga tattgcggca ggggtatttc tctaaagaaa
     7561 aacgttttaa cacattcttt ataaatctga tttataataa aggaggggag gaacctatta
     7621 aaacagagcc tgttaggcag catctataaa aaggatttac aagcagcagt cgtgcaaact
     7681 aagtcattcc ctcaattctt cagtcattgt ttttagtaat gacctgctgt cacttaacgg
     7741 caaatccgta gctaaatccc aactcatcat acctttcagc ttctgttcct ttgcataacg
     7801 ggttttgata cgaatgttat cctgaccgtc aaacacataa gtatctccct gatagatcac
     7861 ttcattctgt gcaggactcg taaccaatcc attctgtaca aaattgaaat aagcctctgt
     7921 cttctttgaa ttatctttgg tcaccccata aaaaggaact cctgccacca gtttttcctt
     7981 cggaatacca tactccaata ccatctgtat atccgaacaa tatttctcta tcggaaagcg
     8041 aaccggtgaa ggaccatagc actgaagtga aataaaatca actgcttcaa tagcttcctt
     8101 actaatctta taacaaacag gatgcagaga tacactgaaa agatacttgt ctcccaacac
     8161 ttcacgcatc ttcaggatag ccaaactata atctttatat tctttctcat tttccgccca
     8221 ctcaaaatca agatcaatgc catccagttt attcttttcc agtacagtct ttatgttctt
     8281 tgcaaacgtc gtacgagcgg cctcatcggc caccatcgct ttccattcgc cactggaagc
     8341 acccaaacgt attttcactt ttgtaccttt tacttttgca cgaaccgatt taatcaaacc
     8401 ttcccaagtg gtcacccctt ttccctgaaa tacacgtgga ttctcaaatg acaatgatcc
     8461 gtctttatta ggatgaacat tcaagaaaat aaggtcgtta cttgcccgca agctttctgt
     8521 agaaatacga ccacggttgt aaaaattacc ccgcacataa gaactgacca tatagtcttg
     8581 ttgtgcaaac aatgataatc caacaaacac aaaaaggaag aatacaattt ttcttagcat
     8641 tagcataatg attgataatt aaaacgttta gatcgcaaaa atacgcatat caaaagcaaa
     8701 cagatgttca aaaacaacta taatacttcc aaaaatcaac ataaagtttt ctattcagaa
     8761 atttaaaaca gataaatatt gaattcttta acatcatcca aagggataag aataatattt
     8821 gcaggtttct actaaaacat aaataaaaga aagagttcca ttttccgcaa aaaaagccta
     8881 tctttgttcc gttaagataa taaatcacgc ataaaactca tgccaggaga ttcattttgc
     8941 atacaatata ccaactgtac gggatgtcca aaaaatgttg agaatatcct tgtatataga
     9001 aacttaccta aaggagagca tatccccaag gataagtgta cgcagaattg tatgcttttt
     9061 atgataaagg gcgaattact tatcaatagc gaagagcatc ccggaataac gttacgcgag
     9121 agacaaattg ttttgcaagc tattggctcc aaggtcgaaa tactggcact gacagatgtt
     9181 gaatacgttg tctactggtt caacgaactg cctttgcttt gcgaagaccg atatagggaa
     9241 atgatggaac aggcggaagc tcctttgacc tacactccac tgattatgag cgaaaggctt
     9301 taccaccttg tcaccagtat gcccgaattc ctcgctgaag aaaacccttg cagcaagtat
     9361 atcgacttaa aatgcaaaga attggttttc ttgattacca acttctatcc gctgccccaa
     9421 ctgggttcat tcttctatcc gatcagcact tatacggaaa gtttccacta tttcgtcatg
     9481 cagaattaca gcaacgtgaa gaacgtggaa gaatttgcgc atctgggagg atatacgacc
     9541 actactttcc gccgactttt caaaaacctc tatggtgtgc ccgtatacga atggatactg
     9601 gaaaagaaac gggaaggaat cctggaagac ctgcaacaca ccaaaatgcg aatcactgaa
     9661 atctgtaaca gatacggatt cgactccctg tcgcatttcg cacacttctg taaagactct
     9721 tttggcgata ccccacgcgc tttacgcaaa aaagcagccg gtggtgagaa aatcggaaag
     9781 gtacaataaa cagtcccatc ctactaatgt gccaatcagt tgcaccatgc gcgcatactg
     9841 gctggcatat tgacacattg gcgcattgat ccattattaa agaattattt ctttaattcc
     9901 ttgctcaatc aatctatttc ccctattttt gcagtccgta agaggtgtaa aacgtcgaaa
     9961 ttttagttct aacaattaaa taatttaaat tcaatcattt atgtggttaa gtaattcatc
    10021 tgtaggaagg aaagtggtga tgagcgttac cggtatcgcc cttgtcctgt ttctaacatt
    10081 tcacatggcg atgaacttgg ttgcaatcat ctcggctgat ggttacaaca tgatttgtga
    10141 gttcctggga gcaaactggt atgcgttagt ggctaccgca ggactagccg ctctttttgt
    10201 gattcacatc atctacgcat tctggctgac aatgcagaat cgcaaagcgc gtggtagcga
    10261 acgctatgca gtggttgaca aaccaaaaac tgtagaatgg gcatctcaaa acatgttggt
    10321 gctgggtctg atcgttatcg taggtcttgg tttgcacctc ttcaacttct gggcaaaaat
    10381 gcagttgccg gaactgatgc acaacatggg catgcacgct gatacactga cgctggctta
    10441 tgccgctaac ggtgcttatc acatccagca gactttctct agcccggttt acgtagttct
    10501 ttacctcgtt tggctgtttg ctttgtggtt ccacctgact cacggtttct ggagctctat
    10561 gcaatcactg ggatggaaca acaaagtatg gatcaatcgt tggaaatgta tttctaacat
    10621 ctattctacg attgttgtac tcggtttcgc actggtagta gtggtattct tcgtgaaaac
    10681 actgatttgt ggcggtgctt gctaaatagt aaattgtaaa tgattaaatt gtaaataata
    10741 ttatgatcaa gatagattca aaaattccag aaggcccggt ggctgagaaa tggaccaact
    10801 ataaagctca ccagaaattg gtgaaccccg ctaataaacg tcgtttggac atcatcgttg
    10861 tgggtacggg tctggcaggt gcttctgccg ctgcttcact tggtgaaatg ggtttcagag
    10921 tattcaattt ctgtattcag gattctcccc gtcgtgcaca ctctatcgct gcacagggtg
    10981 gtatcaatgc tgcaaagaat tatcaaaatg atggtgactc ggtttaccgt ctgttctacg
    11041 atactgtaaa aggtggcgac tatcgtgccc gtgaagcaaa cgtatatcgt ttggctgaag
    11101 tgtctaacgc tatcatcgac caatgtgtag cgcaaggtgt tcctttcgct cgcgaatatg
    11161 gcggtacgct ggacaaccgt tctttcggtg gcgcacaggt atctcgtact ttctacgcta
    11221 aaggccagac tggtcagcag ttgctactgg gtgcttactc tgcattgagc cgtcaggtaa
    11281 acgtaggtac tgttaaactg tatacccgct atgaaatgca ggatgttgtc atcgttgacg
    11341 gacgtgcccg cggtatcatc gcaaaaaatc ttgtaacagg cgaattggaa cgtttcgccg
    11401 ctcacgctgt agtaatcgct accggtggtt atggtaacgc ttacttcctg tctactaacg
    11461 ctatgggttg taactgtaca gctgctatct cttgctaccg caagggtgct gtattcgcaa
    11521 atcctgcata cgttcagatt catccgactt gtattccggt acatggtgac aagcagtcta
    11581 agctgacttt gatgtctgaa tctctccgta acgacggtcg tatctgggtt ccgaagaaga
    11641 aagaagatgc tgtaaaactc cagaaaggcg aaatcaaagg aagtgatatt ccggaagaag
    11701 accgcgacta ttacttggaa cgccgctatc cggcattcgg taacctggtt ccgcgtgacg
    11761 ttgccagccg tgccgctaaa gaacgttgcg acgctggttt cggtgtaaac aacacaggtt
    11821 tggccgtatt cctcgacttc tctgaagcta tcaaccgttt aggtatcgac gttgttcttc
    11881 aacgttatgg taacctcttc gatatgtatg aagaaatcac tgacgttaat ccgggagaac
    11941 tggcaaaaga aattaatggc gtaaagtatt ataatccgat gatgatttat ccggctatcc
    12001 actatacaat gggtggtatc tgggtagact acgaactgca aaccactatc aagggtctgt
    12061 tcgctatcgg tgaatgtaac ttctccgacc acggtgcaaa ccgcctcggt gcttctgcat
    12121 tgatgcaagg tttggctgac ggttacttcg tattgcctta cactatccag aactatctgg
    12181 cagaccagat cactgttcct cgtttctcta ccgatcttcc tgaattcgct gaagctgaaa
    12241 aagctgttca agctaagatc gacaagttca tgagcatcca gggtaaagaa tctgttgatt
    12301 ctatccacaa gaaactgggt catgtcatgt gggaatatgt aggtatggga cgtacagcag
    12361 aaggcctgaa gaaaggtatc gccgaactga aagaaatccg caaggaattc gaaacgaact
    12421 tgtttatccc cggttctaag gaaggtatga acgtagagct tgacaaagca atccgtctgt
    12481 acgacttcat cactatgggt gagcttgttg cttacgatgc attgaaccgt aacgaaagtt
    12541 gtggtggtca cttccgtgaa gaataccaga ctgaagaagg agaagcaaaa cgtgatgacg
    12601 aaaacttctt ctatgtagca tgctgggaat atcaaggtga tgatgaaaag gctccggtat
    12661 tgcacaaaga accgctggta tacgaagcta tcaaggttca gactcgtaac tacaagagct
    12721 aatcggtgaa gttaaacatt taaaagaatt agaagaaaat ggataaaaat atatcattta
    12781 cactgaaggt atggcgccaa gctggtccga aagctaaagg tgcttttgaa acctaccaaa
    12841 tgaaagatat ccccggtgat acttccttcc tcgaaatgct ggatattctg aacgaacagc
    12901 tgatcagcga aagaaaagaa ccggttgtat tcgaccacga ctgccgcgaa ggtatctgcg
    12961 gtatgtgttc tctttacatc aacggacacc cgcacggtcc tgcaacaggt gctactactt
    13021 gccaaatcta tatgcgtcgt ttcaacgacg gcgataccat cactgttgaa ccttggcgtt
    13081 cggctggttt ccctgtcatc aaagacttga tggtagaccg tactgcatac gacaagatta
    13141 tgcaagctgg tggttatgta agcgtacgca caggtgctcc gcaggatgct aacgctatcc
    13201 tgatcgcgaa acctatcgct gacgaagcta tggatgctgc ttcttgtatc ggttgcggtg
    13261 cttgtgtagc tgcatgtaag aatggttctg ctatgttgtt cgtttctgca aaagttagcc
    13321 agttgaactt gctgccgcaa ggtaaaccgg aagctttgcg tcgggcaaaa gctatgttgt
    13381 caaagatgga cgaactggga ttcggtaact gtacaaacac tcgtgcttgt gaagctgaat
    13441 gtccgaagaa tatttctatc agcaacatcg ctcgcttgaa ccgcgacttc atcatcgcaa
    13501 aattaaaaga ctagaaattg ctagatttca atagcgagag cttaatttga ttaatgacag
    13561 aatcccctgc cggctagttc gacaggggat ttctttatat atgagtagat cacaattatt
    13621 attaatacgg atcagtaaca tgaactttta attcataagt ttcaccgatt tcaccttata
    13681 gccaaaactg ttatgaatga gagaattacg ggtgaaagcg aggactgaaa taaggtaaaa
    13741 tcattcgtta ccgcgtaagc gtctccgcga ttctatattg ctgtccgttt ttagctctca
    13801 tatctttgc
//
