Select genomic region:
Overview
1.1
1.2
2.1
4.1
6.1
9.1
10.1
19.1
20.1
30.1
32.1
40.1
41.1

### Identified primary metabolite regions

c00001_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_1)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 1.1 | GR_AA_metabolism,Pyruvate2acetate-formate | SCFA | 39,943 | 77,918 | Pyruvate to acetate-formate E. coli | PFL_acetate | 100%
Region 1.2 | PFOR_II_pathway | SCFA | 82,210 | 105,746 | PFOR II pathway B. thetaiotaomicron | PFORII | 100%

c00002_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_2)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 2.1 | Fumarate2succinate | SCFA | 107,797 | 136,051 |

c00004_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_4)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 4.1 | succinate2propionate | SCFA | 32,622 | 57,967 | Succinate to propionate B. theta | PRO | 33%

c00006_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_6)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 6.1 | Rnf_complex | E-MGC | 37,390 | 63,924 | Acetyl-CoA pathway B. hydrogenotrophica | Acetate | 14%

c00009_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_9)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 9.1 | Acetyl-CoA_pathway | SCFA | 47,334 | 81,465 | Acetyl-CoA pathway B. hydrogenotrophica | Acetate | 61%

c00010_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_10)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 10.1 | Oxidative_glycerol,GR_eut-pdu-related | Putative | 36,785 | 73,443 | Propanediol degradation S. enterica | PDU | 33%

c00019_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_19)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 19.1 | Rnf_complex | E-MGC | 14,827 | 39,838 | Rnf complex C. sporogenes | RNF | 100%

c00020_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_20)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 20.1 | Putrescine2spermidine | Aliphatic_amine | 38,499 | 61,747 | Putrescine2spermidine E. rectale | SPRM | 100%

c00030_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_30)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 30.1 | Others_HGD_unassigned,TPP_AA_metabolism | Putative | 1 | 26,826 |

c00032_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_32)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 32.1 | TPP_AA_metabolism | Putative | 17,538 | 46,334 |

c00040_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_40)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 40.1 | Fumarate2succinate | SCFA | 18,984 | 34,587 |

c00041_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_41)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 41.1 | Others_HGD_unassigned | Putative | 7,232 | 30,175 |

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 1.1 | GR_AA_metabolism,Pyruvate2acetate-formate | SCFA | 39,943 | 77,918 | Pyruvate to acetate-formate E. coli | PFL_acetate | 100%
Region 1.2 | PFOR_II_pathway | SCFA | 82,210 | 105,746 | PFOR II pathway B. thetaiotaomicron | PFORII | 100%
Region 2.1 | Fumarate2succinate | SCFA | 107,797 | 136,051 |
Region 4.1 | succinate2propionate | SCFA | 32,622 | 57,967 | Succinate to propionate B. theta | PRO | 33%
Region 6.1 | Rnf_complex | E-MGC | 37,390 | 63,924 | Acetyl-CoA pathway B. hydrogenotrophica | Acetate | 14%
Region 9.1 | Acetyl-CoA_pathway | SCFA | 47,334 | 81,465 | Acetyl-CoA pathway B. hydrogenotrophica | Acetate | 61%
Region 10.1 | Oxidative_glycerol,GR_eut-pdu-related | Putative | 36,785 | 73,443 | Propanediol degradation S. enterica | PDU | 33%
Region 19.1 | Rnf_complex | E-MGC | 14,827 | 39,838 | Rnf complex C. sporogenes | RNF | 100%
Region 20.1 | Putrescine2spermidine | Aliphatic_amine | 38,499 | 61,747 | Putrescine2spermidine E. rectale | SPRM | 100%
Region 30.1 | Others_HGD_unassigned,TPP_AA_metabolism | Putative | 1 | 26,826 |
Region 32.1 | TPP_AA_metabolism | Putative | 17,538 | 46,334 |
Region 40.1 | Fumarate2succinate | SCFA | 18,984 | 34,587 |
Region 41.1 | Others_HGD_unassigned | Putative | 7,232 | 30,175 |

No primary metabolite regions were found in these records:
  c00003_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_3)
  c00005_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_5)
  c00007_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_7)
  c00008_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_8)
  c00011_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_11)
  c00012_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_12)
  c00013_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_13)
  c00014_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_14)
  c00015_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_15)
  c00016_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_16)
  c00017_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_17)
  c00018_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_18)
  c00021_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_21)
  c00022_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_22)
  c00023_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_23)
  c00024_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_24)
  c00025_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_25)
  c00026_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_26)
  c00027_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_27)
  c00028_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_28)
  c00029_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_29)
  c00031_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_31)
  c00033_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_33)
  c00034_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_34)
  c00035_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_35)
  c00036_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_36)
  c00037_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_37)
  c00038_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_38)
  c00039_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_39)
  c00042_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_42)
  c00043_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_43)
  c00044_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_44)
  c00045_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_45)
  c00046_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_46)
  c00047_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_47)
  c00048_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_48)
  c00049_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_49)
  c00050_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_50)
  c00051_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_51)
  c00052_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_52)
  c00053_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_53)
  c00054_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_54)
  c00055_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_55)
  c00056_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_56)
  c00057_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_57)
  c00058_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_58)
  c00059_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_59)
  c00060_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_60)
  c00061_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_61)
  c00062_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_62)
  c00063_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_63)
  c00064_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_64)
  c00065_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_65)
  c00066_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_66)
  c00067_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_67)
  c00068_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_68)
  c00069_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_69)
  c00070_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_70)
  c00071_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_71)
  c00072_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_72)
  c00073_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_73)
  c00074_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_74)
  c00075_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_75)
  c00076_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_76)
  c00077_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_77)
  c00078_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_78)
  c00079_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_79)
  c00080_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_80)
  c00081_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_81)
  c00082_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_82)
  c00083_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_83)
  c00084_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_84)
  c00085_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_85)
  c00086_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_86)
  c00087_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_87)
  c00088_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_88)
  c00089_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_89)
  c00090_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_90)
  c00091_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_91)
  c00092_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_92)
  c00093_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_93)
  c00094_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_94)
  c00095_gnlPro.. (original name was: gnl|Prokka|MKOCEBHD_95)

Compact view
c00001_gnlPro.. - Region 1 - GR_AA_metabolism,Pyruvate2acetate-formate
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 39,943 - 77,918 nt. (total: 37,976 nt) Show pHMM detection rules used
GR_AA_metabolism: (minimum(1, [Gly_430_pcre, Gly_8-9_TMA, Gly_radical, Gly_radical_scatole, PFL-like, PFL_6_pcresol, PFL_9_tma, PFL_acetate1, PFL_acetate2, PFL_proline, PFL_toluene]) and not NRDD and minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or PFOR_II))
Pyruvate2acetate-formate: ((PFL_acetate1 or PFL_acetate2) and Radical_SAM)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00001_gnlPro.. - Region 2 - PFOR_II_pathway
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 82,210 - 105,746 nt. (total: 23,537 nt) Show pHMM detection rules used
PFOR_II_pathway: cds(POR and POR_N and PFOR_II and EKR and Fer4_16 and TPP_enzyme_C)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00002_gnlPro.. - Region 1 - Fumarate2succinate
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 107,797 - 136,051 nt. (total: 28,255 nt) Show pHMM detection rules used
Fumarate2succinate: (Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or Fer4_7 or SucD_FumR))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

c00004_gnlPro.. - Region 1 - succinate2propionate
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 32,622 - 57,967 nt. (total: 25,346 nt) Show pHMM detection rules used
succinate2propionate: (minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not Cytidylate_kin)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00006_gnlPro.. - Region 1 - Rnf_complex
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 37,390 - 63,924 nt. (total: 26,535 nt) Show pHMM detection rules used
Rnf_complex: (Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00009_gnlPro.. - Region 1 - Acetyl-CoA_pathway
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 47,334 - 81,465 nt. (total: 34,132 nt) Show pHMM detection rules used
Acetyl-CoA_pathway: (CdhC and CdhD and minimum(8, [CbiA, FTCD_C, FTHFS, FeS, Fer2, GCV_H, MTHFR, MTHFR_C, Prismane, Pterin_bind, Pyr_redox_2, Pyr_redox_dim, RACo_C_ter, THF_DHG_CYH, THF_DHG_CYH_C]))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00010_gnlPro.. - Region 1 - GR_eut-pdu-related,Oxidative_glycerol
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 36,785 - 73,443 nt. (total: 36,659 nt) Show pHMM detection rules used
Oxidative_glycerol: ((Fe-ADH or Fe-ADH_2) and Dak1 and Dak2)
GR_eut-pdu-related: (minimum(1, [Gly_430_pcre, Gly_radical, Gly_radical_scatole, PFL-like, PFL_6_pcresol, PFL_acetate1, PFL_acetate2, PFL_proline, PFL_toluene]) and minimum(2, [Aldedh, EutN_CcmL, EutQ, PTAC, PduV-EutP]) and not (PFL_9_tma or Gly_8-9_TMA or NRDD) and not EutB and not EutC and not (POR or POR_N or PFOR_II))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00019_gnlPro.. - Region 1 - Rnf_complex
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 14,827 - 39,838 nt. (total: 25,012 nt) Show pHMM detection rules used
Rnf_complex: (Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00020_gnlPro.. - Region 1 - Putrescine2spermidine
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 38,499 - 61,747 nt. (total: 23,249 nt) Show pHMM detection rules used
Putrescine2spermidine: (minimum(2, [AdoMet_dc, Spermine_synt_N, Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00030_gnlPro.. - Region 1 - Others_HGD_unassigned,TPP_AA_metabolism
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 1 - 26,826 nt. (total: 26,826 nt) Show pHMM detection rules used
Region on contig edge.
Others_HGD_unassigned: (minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl, Carboxyl_trans, CoA_trans, CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans, CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III, ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C, BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C, Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))
TPP_AA_metabolism: (TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or PFOR_II))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

c00032_gnlPro.. - Region 1 - TPP_AA_metabolism
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 17,538 - 46,334 nt. (total: 28,797 nt) Show pHMM detection rules used
TPP_AA_metabolism: (TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or PFOR_II))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

c00040_gnlPro.. - Region 1 - Fumarate2succinate
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 18,984 - 34,587 nt. (total: 15,604 nt) Show pHMM detection rules used
Region on contig edge.
Fumarate2succinate: (Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or Fer4_7 or SucD_FumR))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

c00041_gnlPro.. - Region 1 - Others_HGD_unassigned
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 7,232 - 30,175 nt. (total: 22,944 nt) Show pHMM detection rules used
Others_HGD_unassigned: (minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl, Carboxyl_trans, CoA_trans, CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans, CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III, ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C, BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C, Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.