LOCUS       gnlProkkaCKGJPLGO_3    16443 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CKGJPLGO_3.
ACCESSION   gnlProkkaCKGJPLGO_3
VERSION     gnlProkkaCKGJPLGO_3
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-18 09:44:54
            Original ID  :: gnl|Prokka|CKGJPLGO_3
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16443
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16443
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[6089:6443]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      6090..6443
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..16443
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..16443
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             905..3733
                     /locus_tag="ctg3_1"
                     /transl_table=11
                     /translation="MKNLIALTLLLGGSTLLCAQKPAKTPATYKPVKSEMYRKGWIDFN
                     KNGVKDVYEDPSAPLEARIENLLQQMTLDEKTCQMVTLYGYKRVLKDDLPTPEWKELLW
                     KDGIGAIDEHLNGFQQWGLPPSDNAYVWPASRHAWALNEVQRFFVEDTRLGIPVDFTNE
                     GIRGVESYRATNFPTQLGLGHTWNRELIRQVGLITGREARMLGYTNVYAPILDVGRDQR
                     WGRYEEVYGESPYLVAELGIEMVRGLQHNHQVAATGKHFAAYSNNKGAREGMARVDPQM
                     SPREVENIHIYPFKRVIREAGMLGVMSSYNDYDGIPVQGSYYWLTTRLRGEMGFRGYVV
                     SDSDAVEYLYTKHGTAKDMKEAVRQSVEAGLNVRCTFRSPDSFVLPLRELVKEGGLSEE
                     VINDRVRDILRVKFLIGLFDAPYQTDLAGADREVEKEENEAIALQASHESVVLLKNADE
                     LLPLDINSTKKIAVCGPNANEEGYALTHYGPLAVEVTTVLEGIQEKTKSKAEVLYTKGC
                     DLVDAHWPESEIIDYPLTDDEQAEIDKAVENARQADVAVVVLGGGQRTCGENKSRTSLD
                     LPGRQLQLLQAIQATGKPVVLILINGRPLSINWADKFVPAILEAWYPGSKGGTALADIL
                     FGDYNPGGKLTVTFPKTVGQIPFNFPCKPSSQIDGGKNPGPTGNMSRINGALYPFGYGL
                     SYTTFEYSDLDITPRVITPNESATVRLKVTNTGKRAGDEVVQLYIRDVLSSITTYEKNL
                     AGFQRIHLEPGEAQELSFTIDRKHLELLDADMKWVVEPGDFVLMAGASSEDIRLNGTLT
                     VEDYQTRAKAIEAQKPAKRVSASTNPEDAENVLDEKINTAWQGNKGDYITFALKNGAKV
                     DKVAIAFTRDNNLPATFEIQLSGGGGQFLTVYSGTVSEYGKLISYPFKGTTASDLRIVL
                     NDDRVSIAEVKF"
     CDS             3835..4962
                     /locus_tag="ctg3_2"
                     /transl_table=11
                     /translation="MKTLLFCMLGLGLTACGSSPKGTNGDQDELAMLIGTYTNGSSKGI
                     YTFRFNQETGTAVPLSSAALPNPSYLVPSGDGEFVYAVSEMNDSTAALSSLSLDRETGE
                     LRLLNTVPTFGADPCYVATNGREVLTANYSGGTMSVFPLQKDGTLAPADTLFQGSATGP
                     DAIRQATPHIHCTVFSPDGKYIFATDFSADRILRFVMHPDDPIPHASLEAVDIEADSGP
                     RHLTFSPNGKFAYLITELSGKVIAFSYDDGCLEQIQTITADTVAARGSADIHLSPDGKY
                     LYASNRLKEDGIAIFAVNPENGTLAKVGYQPTGIHPRNFNITPNGKYLLAACRDSNVIQ
                     VYKRNEVTGLLEDTHQDIVVDMPVCVQFVSSVNNL"
     CDS             5033..6082
                     /locus_tag="ctg3_3"
                     /transl_table=11
                     /translation="MKKNILMLSALFLSITAMAQTDVTTGVMRGKDYGVTYMLPKTEIE
                     IVLQATKHTYTPGEFCRYADRYLRLNNVSAEPEEFWTLDKIETRIAGVPDKDNVYFVKM
                     KDKTVAPLMELTEDGIVRSINIPFSGKPAAKTPEAKATESSIDPRSFLTEEILMSNSSA
                     KMAELVAKEIYSIRESKNALLRGEADNMPKDGAQLKLMLDNLNQQETAMTEMFSGKIKK
                     EPKTFTIRLTPKEMKDEVAFRFSRKLGVVANNDLAGEPYYISVTDLKSPDVSATEEGKK
                     KVDGVAYNLPGKAQVTLVYNNKKLFDDQLPITQFGTVEYLAPVLFNKNSTIKVLFDTAT
                     GGLIKVDRE"
     CDS             complement(6090..6443)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_4"
                     /sec_met_domain="PqqD_RRE (E-value: 4.4e-09, bitscore:
                     29.9, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 2.9e-15, bitscore: 50.3,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMEIPEGKVSLLDAVPVRCGHITTEWEGECAVLAYPRFKYEWMRR
                     FLLPKGMSPDIHVRLEEHGTAVWNLIDGHRTVREIIYLLARHFGEEENYIPRVTAYVMQ
                     LRKDGFIQLTIRN"
     CDS             complement(6463..7854)
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 101.4; E-value: 7.2e-31)"
                     /gene_kind="transport"
                     /locus_tag="ctg3_5"
                     /transl_table=11
                     /translation="MTEQLKLKLNDSKATRWGALVIVAFTMMAAYYVNDVVAPLKTMLE
                     TDLAWSSTDFGFFTGGYSFLNVFFLMLIWGGLILDRFGIRFTGKLATILMVGGTALEYY
                     AMTGLAGADATLFGINEIFGYKTGVFVAFAGYSIFGVGAEVAGITVSKIIAKWFKGKEL
                     ATAMGVQVALARIGSQAGYAVAIPLARAFGISTPVLLGLVLLLGGMIAFFVFAVMDKKL
                     DKQMEAAAIAAGTEDEEEKFSFKDVKNILVNPGFWLIALLCVLFYSCVFPFQKFASELM
                     IIKYGINENVAGTFAGLPALGALILTPVFGGFIDKRGKSASIMLLGSAMLICVHFIYAI
                     PDINYWLVAIVLMIILGIAFSLVPSAMWPAVAKIFPVSQLGTAYALIFFIQNIGLWGIP
                     TLIGWVLDAYCISGKKPDGTNMYDYTVPMCIFTGIACLSLIVALLLKKADKKYGYKLEE
                     PNIQK"
     CDS             complement(8008..8397)
                     /locus_tag="ctg3_6"
                     /transl_table=11
                     /translation="MYLLLVILMLIASVLMCFIVLIQNSKGGGLASGFSSSNQIMGVRK
                     TTDFLEKATWTLAAVMVVFSIVSAYTIPSSTGKGGDVILEQAQQEEKTNPYNMPVGTEA
                     PQSEAPAATTPAETPAPAAEAPAAE"
     CDS             complement(8402..9175)
                     /locus_tag="ctg3_7"
                     /transl_table=11
                     /translation="MTPTHLQQWIQHPETLNRDTLYELRTLVARYPYFQSLRLLYLKNL
                     YLLHDINFGAELRKAVLYVADRRVLFYFIEGDRYTLKSRKVSSLFSGDLEKEPSVDRTL
                     SLIDAFLATVPEEHSQHTELDYAVDYTAYLMQEEPGVDAEDESEVPKLRGHELIDDFIQ
                     KSESSDASDTRREFLVEKEEETEEEEEPSVSPVTEELDDSCFTETLAKIYIKQHRYDKA
                     LEIIKKLSLNYPKKNAYFADQIRFLEKLIINAKSK"
     CDS             complement(9180..9704)
                     /locus_tag="ctg3_8"
                     /transl_table=11
                     /translation="MDWIKKAAFASLLVSLLFLVNSCSMKLGLAPISSIDYTKVKTISI
                     ADFQNRAEYVYAPLATEFNQKMKDMFIQQTRLQLVNSGGDLEIDGEITGYNQYNESVDA
                     SGYSSKVKVTLTVNVRYTNNTNHEEDFEQQFSAFQTYDSSKLLTEVQDQLITLMVKDIA
                     EQIFNATVANW"
     CDS             complement(9691..10941)
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 380.4; E-value:
                     2.1e-115)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg3_9"
                     /transl_table=11
                     /translation="MTKAEIQQVKLRFGIIGNNEALMRAIDIAIQVAPTDLSVLITGES
                     GVGKESFPQIIHQYSRRKHGQYIAVNCGAIPEGTIDSELFGHEKGAFTGAIGERKGYFG
                     EANGGTIFLDEVGELPLPTQARLLRVLESGEFIKVGSSKVEKTDVRIVAATNVNLTQAI
                     ADGRFREDLYYRLNTVPIQVPPLRERGEDVVLLFRKFASDFAEKYRMPAIQLTEDGKQV
                     LLGYSWPGNVRQLKNITEQISIIETNREINASILKGYLPEQNNMQRLPALFGVKEDKSF
                     GSEREILYQVLFDMRQDVTDLKKLVHEIMAERGTVANPAVATSAYYTPATPAVVPPVTS
                     SVPTIIHPSAKPVTPVDDDFQDTEEYVEESLSLDEVEKEMIRKALEKHHGKRKSAAQDL
                     NISERTLYRKIKEYGLD"
     CDS             complement(10943..12040)
                     /locus_tag="ctg3_10"
                     /transl_table=11
                     /translation="MEDNKIRVGITQGDINGVGYEVILKTFADPVMLELCTPIIYGSPK
                     VAAYHRKSLDLSTNFSIVNSASEAVPNRLSVVNCTDDEVKVEFSKPDVEAGKAALGALE
                     KAIEEYKEGMIDVIVTAPINKHTIQSEEFAFPGHTEYIEQKLGDGEKALMILMKDDFRV
                     ALVTGHIPVKEIAGSITKELIQEKLKIFNRSLKQDFAISAPRIAVLSLNPHAGDGGLLG
                     TEEQEIIIPAINEMAAKGMLCYGPYPADGFMGSDNFTHFDGILAMYHDQGLAPFKALAM
                     DEGVNYTAGLPVIRTSPAHGTAYDIAGKGIASEDSFRQAIYVAIDVFRNRQREKEAHAN
                     PLRKQYYEKRDDSDKLKLDSVEEDL"
     CDS             complement(12046..13101)
                     /locus_tag="ctg3_11"
                     /transl_table=11
                     /translation="MRKHLFYLSMVLVLTLFSACGGGKKGVFTPTSSGRAYEVLVVVEP
                     GLWERPAGRALFDVLDSDVPGLPQSERSFRIMYTAPSNYDATLKLIRNIIIVDVNKDLY
                     TQPKFKYARNVYAAPQSILTIQAPDEASFEKFVEENRQVIIDFFTHAEMNRQISVLKDK
                     HSDYIATKVKSLFDCDVWVPGELTSTKEGENFFWAGTNAATGDQNFVIYSYPYTDKDTF
                     TKEYFVHKRDSVMKANIPGAREGMYMSTDSLMTDVRPISVQGDYALEARGLWRIKGDFM
                     GGPFVSHVRLDKANQRIIVSEIFIYSPDKMKRNLVRQMEASLYTLKLPGSKLEGAEIPV
                     GVTAKDTTNNK"
     CDS             complement(13172..14212)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_12"
                     /sec_met_domain="PF04055 (E-value: 4e-16, bitscore: 53.7,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQKRPLLGLTLSELQNVVKNLGMPGFSAKQIASWLYDKKVTSIDE
                     MSNLSLKHRELLKEIYEVGAEAPVDAMRSVDGTVKYLYRAGEGHFVEAVYIPDEDRATL
                     CVSSQVGCKMNCKFCMTGKQGFTANLTSNQIINQINSLPERDKLTNVVMMGMGEPLDNL
                     DEVLKALEIMTASYGYAWSPKRVTLSSVGLKKGLQRFIEESDCHLAISLHSPIPLQRRE
                     LMPAEKAFSITEIVELLRNYDFSKQRRLSFEYIVFKGVNDSLPYAKELLKLLRGLDCRI
                     NLIRFHAIPGVNLEGADMETMTAFRDYLTSHGLFTTIRSSRGEDIFAACGMLSTAKQEE
                     NKEELI"
ORIGIN
        1 attttgagga ctgagattaa agtgcaaatc aacgacgcac tgcatgctta cttaccattt
       61 ctgcccgctg tcaaatccag tcaaccccat gactttgtaa cggtctgaaa tttaaaagat
      121 tgcgtaactc attgctaagt agggagggtg aaaaagggat aaatgctact ttatttttca
      181 tcctctaccg ctttctttgg cccaaagata catattcttt tattagcaat caccatatat
      241 ttacaaatat tagctaatac tgacttttcg tgataaaaac aataatcttc catacataga
      301 atatgtgcac cccattgtca tcaatgttca aacagctacc aaagccagta tccgttgacg
      361 gaattacccc ctgcaagagg gaatatctat cttctgtaat ggatatttgc acaaaagaga
      421 tgggaagtta acggaaaaag tctctgaagt taactgaaaa accggaaaga attaaggaag
      481 caatctatcc caaactttgg tttttccata cccagccttg agatgtctaa accaaggttt
      541 ggtttagaca tcccaaggtt gaaaagaaag ttcttccgta caagcaacaa ttccgccaac
      601 agattcctat tatataaata caccctcgtt taacagatgt agccgtaata cttgtataca
      661 ccgcgattgc atctactttt caggttatta tagtgttctt tctttttaaa agtgaatgat
      721 atgtttcgtc taataatgat ttgaattccc cggtagcgtc ttggaggata tttttagtaa
      781 gaggaagacc cttcggacaa taaaagccga tacttcggac tattttatcc ctttatttca
      841 cacattagcc gtatttttgt caacaaaaga aacaataata accaagagat ttttagaaca
      901 tatcatgaag aaccttattg ccctaaccct gctgcttgga ggaagcacac tgctctgcgc
      961 acaaaagcct gccaaaacac cggcaaccta caagccggtg aaaagtgaaa tgtaccgcaa
     1021 aggttggata gacttcaaca aaaacggagt gaaagacgtg tacgaagacc cctccgcccc
     1081 gctcgaagca cgcatcgaaa acctgctgca acagatgacg ctggacgaaa agacctgcca
     1141 aatggtcacc ctctacggct acaaacgcgt actgaaagac gacctcccca cccccgaatg
     1201 gaaagagctg ctctggaaag acggcatcgg cgccatcgac gaacacctga acggcttcca
     1261 gcaatggggg ctgcctccct cggacaatgc ctacgtctgg cccgcctcgc gccacgcctg
     1321 ggcactgaac gaggtgcaac ggttctttgt ggaagatacc cgtctcggca tccccgtaga
     1381 ctttaccaac gaaggcatac gcggcgtgga aagctaccgc gccaccaact tccccaccca
     1441 actgggactg ggacatacct ggaaccgtga actgattcgc caagtaggac tcatcaccgg
     1501 acgcgaagcc cgcatgctgg gctacaccaa cgtctacgcc cccatcctcg acgtaggacg
     1561 cgaccagcgc tggggacgct acgaagaagt ttacggcgaa tctccctacc tcgtagccga
     1621 actgggcatc gaaatggtgc gcggcttgca gcacaaccac caagtggccg ccaccggcaa
     1681 gcactttgcc gcttacagta acaacaaagg cgcccgcgaa ggcatggcac gcgtggaccc
     1741 gcaaatgtcg ccgcgcgaag tggagaacat acacatctac cccttcaaac gcgtcatccg
     1801 ggaagctggc atgctgggcg taatgagttc gtacaacgat tacgacggca tccccgtgca
     1861 gggcagctac tactggctca ccacccgcct gcgtggcgaa atgggattcc gtggctacgt
     1921 cgtatccgac agtgacgccg tagaatacct ctacaccaag cacggcaccg ccaaagacat
     1981 gaaagaagcc gtccgccaaa gcgtggaagc cgggctgaac gtacgctgta ccttccgctc
     2041 gcccgactcc ttcgtccttc ccctccgcga actggtgaag gaaggcgggc tgagcgaaga
     2101 agtcattaac gaccgtgtgc gcgacatcct ccgggtaaag ttcctcattg gtctgttcga
     2161 tgccccctac cagacagacc ttgccggtgc cgaccgtgaa gtggaaaaag aagagaacga
     2221 agccatcgcc ttgcaggcat cccacgagtc cgtcgttctg ctgaagaatg ccgatgagct
     2281 gttgccctta gacatcaact ccaccaagaa gattgccgtc tgtggtccca atgccaatga
     2341 agaaggctac gcgctgaccc attacggccc acttgccgta gaagtgacca ctgtactgga
     2401 aggcattcaa gaaaagacaa aaagcaaggc agaggtgctc tacaccaaag gctgcgacct
     2461 agtggatgcc cactggcccg aaagtgaaat catagactat cctctgaccg acgacgagca
     2521 agccgagata gacaaagccg tagaaaatgc ccgccaagct gatgttgccg tcgtagtatt
     2581 gggcggcgga caacgcacct gcggcgaaaa caaatcgcgc accagcctcg acctgcccgg
     2641 ccggcagttg caactgcttc aagccataca agccacgggc aagcccgtcg tactgatact
     2701 catcaacgga cgcccgctct ccatcaactg ggcagacaag ttcgtccccg ctatcctcga
     2761 agcctggtat cccggctcca aaggcggaac agccctggcc gacatcctct tcggcgacta
     2821 caaccccggt ggaaagctga cggtgacctt ccccaagacc gtagggcaaa tccccttcaa
     2881 cttcccctgc aaaccttctt cacagataga cggcggtaag aatccgggac ctacgggcaa
     2941 catgtcacgc atcaacggag cactctaccc cttcggttac ggcttgagct acaccacctt
     3001 cgagtactcc gacctcgaca tcaccccccg agtcatcacc ccgaacgagt ctgccaccgt
     3061 ccgcctgaag gtgaccaaca ccggcaaacg tgccggagat gaagtagtgc agctctatat
     3121 ccgcgacgta ctgagcagca tcaccaccta cgaaaagaat cttgcaggct tccagcgcat
     3181 ccacctcgaa ccgggcgaag cccaggagct gtccttcacc atcgaccgca agcacctgga
     3241 gcttctggac gccgacatga aatgggtggt ggaacccggc gacttcgtac tcatggccgg
     3301 cgcctcttcc gaagacatcc gcctgaacgg aacgctgacc gtagaagact accagacccg
     3361 tgccaaagcc attgaagccc aaaaaccagc aaagcgtgtg agtgccagca ccaacccaga
     3421 ggatgccgaa aacgtgctcg acgaaaaaat caataccgca tggcaaggaa ataagggaga
     3481 ttatattacc tttgccttga agaacggagc caaggtagat aaagttgcca ttgcctttac
     3541 acgtgacaac aacctgccgg caaccttcga aatccagctc tcgggcggtg gcggacagtt
     3601 cctcaccgta tattcgggca ccgtcagcga atacggcaaa ctgatttcct atccgttcaa
     3661 aggcactacc gccagcgacc tccgcatcgt gctgaacgat gaccgcgtca gtattgccga
     3721 agttaaattt taatgtgcta atgtgccaat atgctaatgt accaatgacc atgcagcata
     3781 tacagcgcag ccaattagca cattagcata ttggcacatt aacacattaa attaatgaaa
     3841 acacttcttt tctgtatgct cggattaggt ttgacagcat gtggctcttc tccaaagggc
     3901 actaacggtg accaggacga actcgccatg ctaataggta cttacacgaa tggctcaagc
     3961 aagggtatct ataccttccg ctttaatcag gagacgggaa cagccgttcc gctcagttca
     4021 gcggcattgc ccaatccctc ctacctcgtc ccctcgggag atggcgaatt tgtctatgcc
     4081 gtcagtgaaa tgaacgacag cacagcagcc ctcagctccc tttccttaga ccgggaaacg
     4141 ggagaactgc gcctgctgaa caccgttccc accttcggcg ccgacccctg ctacgtggcc
     4201 accaatggcc gggaagtgtt gactgccaac tacagcggtg gaaccatgtc cgtctttcct
     4261 ttacagaaag acggtacttt ggctcctgca gacacgctct ttcaaggctc tgccaccggt
     4321 cccgacgcca tacggcaagc cactccccac atccattgca cggtcttttc accggacgga
     4381 aagtatatct tcgccaccga cttcagtgcc gaccgcatcc tgcgctttgt gatgcacccc
     4441 gacgacccta ttcctcatgc ttctctggaa gccgttgaca ttgaagcgga ttccggcccg
     4501 cgccatctga cattcagccc taacgggaag tttgcctatc tcatcaccga actgtccggt
     4561 aaggtcattg ccttcagtta cgacgacggc tgcctggaac agatacagac tatcacagcc
     4621 gacaccgtag ccgcccgtgg aagtgcagac atccacctca gtccggatgg gaaatacctc
     4681 tacgccagca accgtctgaa agaagacggc atcgccatct ttgccgtgaa tcccgaaaat
     4741 gggaccttgg caaaggtagg ttatcagccc accggcatcc atccccgcaa cttcaacatc
     4801 acgcccaacg gtaaatactt gcttgccgcc tgccgcgaca gcaatgtcat tcaggtatac
     4861 aaacgaaacg aagttaccgg actcttggaa gatactcatc aggacattgt agtcgacatg
     4921 ccggtttgcg tacagttcgt cagctctgtt aataatttat aaagcaatat ttagcaaaga
     4981 taacttcatt aactttgtcc cttagctaaa tcagtctaaa cgaatgtaca ttatgaagaa
     5041 gaatatattg atgctctcag ctctgttctt gtctatcact gccatggcgc aaacagacgt
     5101 aaccaccggt gtgatgcgtg gcaaagacta cggagtgact tatatgttgc ccaaaacaga
     5161 aatagaaatc gtattgcaag ccaccaaaca tacttacact cccggagaat tttgcagata
     5221 tgccgaccgc tatctgcgtc tcaacaacgt gtctgccgaa cccgaggagt tctggacact
     5281 ggataagata gaaacccgca tagccggtgt accggataag gacaacgtct atttcgtgaa
     5341 gatgaaagac aagaccgtag caccccttat ggagcttacc gaagacggaa ttgtccgctc
     5401 catcaacatt ccgttcagcg gtaagcctgc tgccaagacg cccgaagcca aagccaccga
     5461 aagcagcatt gacccacgca gttttctgac ggaagaaata ctgatgtcca actccagtgc
     5521 caagatggcc gagctggtgg ctaaggaaat atacagcatc cgcgaaagca agaatgccct
     5581 cctgcgcggc gaagcagaca atatgcccaa ggacggcgcc caactcaagc tgatgcttga
     5641 caatctgaac cagcaggaaa cggctatgac ggaaatgttc tcgggcaaaa taaagaaaga
     5701 acccaagaca ttcaccatcc ggctgacgcc taaagagatg aaagatgaag tggctttccg
     5761 tttttcccga aagctgggag tggtggccaa taatgacctt gccggtgaac cgtattatat
     5821 cagcgtcacc gacctcaaaa gtcccgatgt atctgccacc gaggaaggca aaaagaaagt
     5881 ggacggtgta gcctataacc ttccgggcaa ggcacaagtg acattggtgt ataacaataa
     5941 gaaattgttt gacgaccaac ttcccattac ccaattcggc accgtagaat acctcgcacc
     6001 ggtactgttc aacaagaatt ctaccatcaa agtgctgttt gatacggcaa cgggaggatt
     6061 gataaaagtg gatagggaat aaaggaattc taattccgga ttgtcaactg gataaatcca
     6121 tccttacgca actgcattac gtaggcggtg acccggggaa tataattctc ttcctcccca
     6181 aagtgcctgg caagtagata gatgatttcg cgcacggtac gatgtccatc tatcagattc
     6241 cagacagctg taccgtgttc ttccagcctc acatggatgt caggagacat ccccttcggc
     6301 aataaaaaac gacgcatcca ttcgtattta aaccgtgggt aggcgagtac ggcgcactca
     6361 ccttcccatt cggttgttat atgtccacag cggaccggaa cagcgtccaa cagacttact
     6421 tttccttcgg gtatttccat catacggtat ccgcttttcc tattatttct gaatattagg
     6481 ctcttccagc ttataaccat acttcttgtc tgccttcttc agcagtagag ccactataag
     6541 ggacaagcag gcaataccgg taaaaatgca cataggcacc gtatagtcat acatattcgt
     6601 tccatctggt ttcttgccgg atatacaata ggcatcaagc acccacccta tcaatgtagg
     6661 aataccccaa agaccgatat tctggataaa gaaaatcaat gcgtatgccg tacccaactg
     6721 gcttaccggg aatatcttgg ccacagccgg ccacatggca gaaggtacca gcgagaaagc
     6781 gatacccaaa attatcatca gcacaatagc taccagccaa tagtttatat cgggaatagc
     6841 ataaatgaaa tgcacacata tcagcatggc cgagcccagc agcatgatag atgcggactt
     6901 gccccgcttg tcaatgaaac caccaaagac cggagtcaga atcagcgctc ccaatgccgg
     6961 aagtccggca aatgtaccgg ccacattctc attgataccg tatttgataa tcatcaactc
     7021 ggaagcaaac ttctggaatg ggaatacaca agagtagaac aatacacaca gcaatgctat
     7081 cagccagaaa ccgggattga ccagaatatt cttcacatcc ttaaaagaga acttctcttc
     7141 ctcatcttcc gtaccggcag caatggcagc agcttccatc tgtttgtcca gcttcttgtc
     7201 catcactgca aagacgaaga aagcaatcat accgcccaac aacagaacca aacccaacaa
     7261 caccggtgtg gaaataccga aagcgcgggc caaaggaatg gctacggcat aaccggcttg
     7321 cgaaccgata cgtgctaaag cgacttgtac ccccatagcc gtggcaagct ctttcccctt
     7381 aaaccacttg gctatgattt tggaaactgt aataccggcg acctccgctc ctactccaaa
     7441 aatggaataa ccggcaaaag caacaaacac acccgtttta tagccaaata tttcattgat
     7501 tccgaataaa gtcgcgtcgg caccggcaag tcccgtcatt gcatagtatt caagtgctgt
     7561 accacctacc atcaggatag ttgccagctt tccggtgaaa cggataccaa agcggtcgag
     7621 gattaatcct ccccaaatca acatcaggaa aaaaacattc agaaaactat aaccaccggt
     7681 aaagaatccg aaatcggtac tcgaccaagc caagtccgtt tccaacattg tcttcaacgg
     7741 tgctaccacg tcgtttacat aataagctgc catcatcgtg aaggcaacaa tcaccaatgc
     7801 cccccaacgg gtagccttgg aatcattcaa tttaagtttg agttgttctg tcattgtact
     7861 atttggattt caatttatta atcagattgc ataaattgct gacaaaggta aataaatact
     7921 tcatcaaaac gaaaaaaggc tgacaccttt tcagtatcaa cctttctctt atttttccaa
     7981 gcgggagtca tccgcaatat ccttatctta ttctgctgca ggggcttctg ctgcaggagc
     8041 aggagtttca gccggagttg tagctgcagg ggcctccgat tgcggagctt ctgtacctac
     8101 gggcatgtta taaggattag ttttttcttc ttgttgcgcc tgttccagaa tcacatcacc
     8161 gcccttgcct gtggaagaag gaatagtgta agcagaaaca atactgaaga ctaccatgac
     8221 agctgccaga gtccaggttg ctttttccaa aaagtccgta gtcttgcgca cacccataat
     8281 ttggttggat gatgaaaagc ctgatgccag accacctcct ttagaatttt gaatcaatac
     8341 aatgaagcac atcagcacag atgcaatcag cattaagata actaataata aatacatttt
     8401 gttattttga tttagcgtta ataatcaatt tctccaaaaa tctgatttgg tctgcaaagt
     8461 aagcattttt ttttggataa ttcaaactta attttttaat aatttcaagc gccttgtcat
     8521 atcggtgctg ttttatatag attttggcta aagtttccgt aaaacagcta tcgtccaact
     8581 cttccgttac cggcgatacg gagggttctt cctcttcttc agtctcttcc tccttctcta
     8641 caagaaactc ccttctcgta tccgaggcat ccgaagactc actcttttgg ataaagtcat
     8701 ctatcaattc atgcccgcgc agtttaggca cttccgactc atcttctgca tccacaccgg
     8761 gttcttcctg cattaaatag gccgtataat ccaccgcata atccagctcc gtatgctgtg
     8821 aatgctcttc gggaacagta gccagaaatg cgtcaatcaa ggaaagggta cggtccacac
     8881 tcggctcttt ctccaaatcg ccggaaaaca gcgacgagac cttccgggat ttcaaagtat
     8941 agcggtcacc ctctataaag taaaacagca cacgacggtc tgccacatac aacacagcct
     9001 tgcgcaactc cgcgccaaag ttgatgtcgt gcagcagata gaggtttttc agatagagca
     9061 aacggagcga ctggaaataa ggatagcgtg ccaccaatgt gcgaagctcg tacaaagtat
     9121 ccctattcag cgtctcggga tgctgaatcc attgttgcaa atgggtaggc gtcatgagtt
     9181 taccagttag ctacagttgc attgaaaatc tgttcggcaa tgtctttcac catcaaggtt
     9241 atcagctggt cctgcacttc ggtcagcaat tttgaggaat cataggtctg gaaagccgag
     9301 aactgctgtt caaagtcctc ctcatggttc gtgttattgg tgtaacgcac gttgacagtc
     9361 agcgtcacct tcaccttcga agagtagccg ctggcatcca ccgattcatt atattgattg
     9421 tagccggtta tttctccgtc tatttccagg tctcctccgg aattcaccag ttgcaggcga
     9481 gtctgctgaa tgaacatatc cttcattttc tggttaaatt ctgttgccag cggtgcatat
     9541 acatactctg cccggttctg gaaatcggca atggaaatcg tttttacctt tgtatagtcg
     9601 atagagctta tcggagcaag tcccaacttc atactacatg aattcaccag aaataacaag
     9661 cttaccaaca aggaagcaaa tgccgctttt ttaatccaat ccatattctt ttatctttct
     9721 gtataacgta cgctcagaga tattcaaatc ctgagccgca ctcttacgct tgccgtgatg
     9781 tttttcaagc gccttacgta tcatttcttt ctccacttca tccagggaga gtgactcctc
     9841 cacatattct tccgtatcct ggaaatcatc gtccaccgga gtaaccggct ttgccgaagg
     9901 atgtataatg gtggggacac tggatgttac cggaggtacc accgccggag tagccggcgt
     9961 atagtaggcc gatgtggcaa ccgccggatt ggctaccgtt cccctttcag ccataatctc
    10021 atgcaccaac tttttcaagt ccgttacatc ctggcgcata tcaaacagaa cctggtagag
    10081 aatttcccgt tcactcccaa agctcttgtc ctccttcact ccaaacaagg caggcaggcg
    10141 ctgcatattg ttctgctcag gcagatagcc cttcagtatg gatgcattga tttcacgatt
    10201 ggtctcaatg atggatatct gctcggtgat attcttcaac tggcgcacat tacccggcca
    10261 tgagtagccc agcaacactt gcttgccgtc ttccgtcagc tgaatggcag gcatacggta
    10321 cttttctgca aagtccgaag caaactttcg gaacagcagc accacgtctt caccgcgttc
    10381 gcgcaatgga gggacctgaa taggaactgt gttcaaacgg taatacaagt cttcacgaaa
    10441 acgtccgtca gcaatggctt gtgtcaagtt tacattggta gcggcaacaa tacgcacatc
    10501 ggtcttttcc accttagaag aacctacttt gatgaattca ccgctctcga gcacacgcaa
    10561 caagcgtgcc tgggtaggca aaggcaattc gccgacttca tcaaggaaga ttgttccgcc
    10621 gttggcctca ccgaaatacc ccttccgttc gccgatagcc ccggtaaatg cgcccttctc
    10681 atgaccgaac agttccgagt caatcgtccc ttcgggaatg gctccacagt tcacggcaat
    10741 gtactgtcca tgcttgcgcc ggctgtactg gtgtattatc tgcggaaagc tctcctttcc
    10801 cacaccactc tctccggtaa tcagtacaga caagtcggtg ggcgctacct ggatagcgat
    10861 atcaatggca cgcatcagcg cttcattgtt gccgataatg ccgaaacgta attttacttg
    10921 ttgtatttcc gcttttgtca ttctacaaat cttcttctac actatcgagt ttcagtttgt
    10981 cgctatcgtc acgtttctcg taatattgct tgcgcagcgg atttgcatgt gcctctttct
    11041 cacgctggcg gttacggaac acatctattg ccacatagat agcctgccgg aatgaatctt
    11101 cagaggcgat tcctttcccg gcaatatcgt aggccgtgcc atgagcaggc gaagtgcgta
    11161 tcaccggcaa gccggcagta tagttcacgc cctcgtccat agccaatgcc ttgaacggtg
    11221 ccagcccctg gtcgtgatac atggccagga taccatcaaa atgggtaaag ttatctgagc
    11281 ccataaaccc gtctgccgga taaggaccat agcaaagcat acccttagca gccatttcgt
    11341 tgatggccgg aatgataatc tcctgctctt cagttcccag caatccgccg tctcctgcat
    11401 gcggattcag cgaaagcact gcaatacgcg gtgcgctgat agcaaaatcc tgcttcaagg
    11461 agcggttgaa tatcttcagt ttttcttgta tcagttcttt ggtgatgctt ccggctatct
    11521 ctttaacggg aatatgtccg gtcaccaatg ctacccggaa gtcatctttc atcagaatca
    11581 taagggcctt ctcgccatct cccaattttt gctctatata ctccgtatgt ccggggaagg
    11641 caaactcctc cgactggatg gtatgcttgt tgatgggagc tgtgacaatc acgtctatca
    11701 ttccctcctt atattcctca atggcttttt ccagtgcacc aagtgcagct ttaccagctt
    11761 caacgtcagg tttagagaac tcaaccttta cttcatcatc cgtacagttc actacactca
    11821 agcgattggg aaccgcttcg gaggcagagt tgacgatact gaaattggta gacaagtcca
    11881 atgatttacg atgataagct gccactttag gcgaaccgta gataatcggc gtacacaatt
    11941 ccagcatcac cgggtctgca aacgtcttta aaatcacttc ataccctaca ccattaatgt
    12001 cgccttgtgt aatgccgact cttattttgt tgtcttccat ttttattact tattattagt
    12061 agtatctttt gcggttacgc ctaccggaat ttccgcacct tccagcttgc tgccaggcag
    12121 tttcaaggta tagagcgaag cctccatctg acgtaccaga ttacgtttca ttttatcagg
    12181 tgaataaata aatatttcag atacgataat acgctgattg gctttgtcca aacgtacatg
    12241 cgatacgaac ggaccgccca tgaagtcacc ctttatgcgc cacaagccgc gggcctccaa
    12301 tgcatagtct ccctgcacac tgatagggcg tacatcggtc atcagagaat ccgtcgacat
    12361 atacatgcct tcacgggcac cagggatgtt agccttcatc acggaatcgc gtttatgaac
    12421 aaaatattct ttagtaaacg tatccttatc cgtataagga taagagtaga ttacaaagtt
    12481 ctggtcgccg gtagctgcat tcgtacctgc ccagaagaag ttctccccct ccttggtaga
    12541 tgtcagttcg cccggcaccc atacatcgca atcgaacagg cttttcacct tcgttgctat
    12601 atagtcgcta tgcttgtcct tcaatactga aatctgacga ttcatttccg catgagtaaa
    12661 gaaatcgatg attacctgcc tattctcctc cacaaatttc tcgaacgaag cctcgtccgg
    12721 cgcctggata gtgagaatgg actgaggagc agcatataca ttccttgcat acttgaattt
    12781 aggctgggta tagaggtctt tgttcacatc gacaataatg atattgcgaa tcagttttaa
    12841 agtggcatca taattggaag gggcagtata catgattcgg aatgaacgtt ctgactgggg
    12901 aagccccgga acatcagaat caagcacatc gaaaagcgcc ctaccggcag gacgttccca
    12961 caagccgggc tccaccacta ccagaacttc atacgcacga ccactggagg tcggagtaaa
    13021 cacacccttt ttaccaccac cgcaagcgga aaaaagtgtc agtacgagaa ccatacttaa
    13081 ataaaacaag tgctttctca tatctctatc attttagttt ttcacaaagc tacgaagaat
    13141 gcgtaatatc ctccctacct aagttaataa tttatattaa ttcttcttta ttctcctcct
    13201 gcttggcagt ggacaacatg ccacaagcgg caaatatatc ctctccacgc gatgaccgta
    13261 tagtggtaaa cagaccgtgc gaagtcagat aatcacggaa cgcagtcatg gtttccatat
    13321 cagccccttc aagattcact ccaggtatgg catgaaaacg aatcaggtta atccggcagt
    13381 ccagcccgcg tagcagcttc agaagttcct ttgcatacgg taacgagtca ttcactcctt
    13441 tgaaaacaat atattcaaaa gatagtctgc gctgtttgct aaaatcatag tttcttaaca
    13501 attccacaat ctccgtgatg gagaacgcct tctctgccgg catcagttcg cggcgttgca
    13561 aaggtatcgg cgaatgaagg ctgatagcca gatggcagtc cgattcctca ataaaacgct
    13621 gcaatccctt cttcaatccc acagaagaaa gtgtaacacg cttgggactc cacgcatacc
    13681 cataagaggc ggtcattatt tccagcgctt tcaatacctc gtccagatta tcaagtggtt
    13741 cacccatgcc catcattacc acattggtaa gcttgtccct ttcgggcaac gaattaattt
    13801 gattaataat ctggttggat gtcagattgg cagtaaaacc ttgtttgccg gtcatacaga
    13861 acttgcaatt catcttacag cccacctgag aggagacaca aagcgtagcc cggtcttcgt
    13921 cgggtatata gacagcttcc acgaaatgcc cctcgcctgc ccggtacaag tatttcaccg
    13981 taccgtctac agagcgcatg gcatctaccg gcgcttcggc acctacctca tagatttctt
    14041 tcagcaattc ccgatgcttc aacgaaagat tgctcatttc gtctatagaa gtcaccttct
    14101 tgtcatacag ccaggaagct atctgcttgg cagagaaacc gggcattccc agattcttca
    14161 ccacattctg caattcagag agcgtcaagc ccaatagagg tcgtttctgc atatcgtttt
    14221 tcattaaaac aaaactcttt caagaatgca aaggtaggaa taaagttgca caaagacaac
    14281 ggagagtgta gaaaatgaaa tgtacagaca atgaaaaagc cgcccggaag taccggacgg
    14341 cttttcaata tgggttttct attcttagaa gaataaataa cgttggtctt ttacgttggc
    14401 tttcagatac aagtcactga tgaactggct tgccatacgt gcatgcatgt tagccaagtt
    14461 agcctcttca gtttccttgt tgaatgtttc gttcagcttc tcttttgcat aaggttgcag
    14521 aacgaataca ccaccgttac ccttgatagg agcactcagc ttgttcactt cggcaataga
    14581 agcgtatgcg cctaccaaag gttcgctgct acgcaatgcc gggatatagg caggagcaga
    14641 gaaagtaacg tgctttacag aatcactgac agcatttgcc atattcttgt actgctcgaa
    14701 cgaagttgca ttggcagcct tcatatcagc cataatcttc tctgctttct tgtcacggag
    14761 aatttcagct ttcaactggt cctttaccaa agccagtggg cgataacctt caggaacaat
    14821 acttgcaaca cctactacca gcatacggtc gctctcgcca cattcgtaca aaccggaaac
    14881 ttcaccggct tttgcctcaa acgcccattt caaagcatct ttggttcctc tgataccacc
    14941 gataccatgt tcagagctgt acaagtcggc tctatccagc aacttgtaac cggcatcttc
    15001 cgcattggca atcattttct ctaaagtatt gtttgcagcg atgaactggc taaactcatt
    15061 gtatgccttg ctgtaagttt ccttgctgaa ttctaccgga cgcttgataa cggctacctt
    15121 atatttatcc ttgacagcct tcttgttggt tacttgcaaa atgacatttg cttgtcccaa
    15181 cgccagattg gtcagttcgt tctgtcccaa agttgtgaca gcggtaatgt atttcaagtt
    15241 gtcaccgtca atctgtgcgc cttcgtagtt agcagaagaa atccaggtag gctcaccggt
    15301 ctgaccgtac ttcttcgcaa cttcagcaaa gctggcacca cccttaatag cattgtagat
    15361 gctgtcggcc aaaatcttcg tcttttcagc atcttcggca actacctgaa tctgacggaa
    15421 ctcgatagag tccggcatgg cagcagtagc caatttcttg aaagagttga gggtattgtc
    15481 agatacgtta taataaggcc cgaacacacc acccaccgca acagagtcca aacgggctgt
    15541 cacatcagca ggcagagact tagtagtgta gaacaagtct gtataaggag cttcggaacc
    15601 ggtagaacgg ataaaggtag tatagtcaga aggattggca gtaagttgtt cggtgtattc
    15661 ttccatttcc ttctggagag cagctctgtc ttctgcactt gcagtaactt gcacatcaat
    15721 gaacttgata ttgcgagttt ccacatattg cttgaactgt tctttcttct tgtcgtatgc
    15781 agccttcaaa tcagaatcct tgataacgat ggtagagtca acgatagaag aatagggaac
    15841 tgcagcaagc agcaggtctg actgctctac tcttgcatca aaagcgtcct gagcttctac
    15901 cgggttggag aaaagggatt ttgtaatcaa agcttgatac ttctcctgaa gacgtgcctg
    15961 gataagggac ttttcgagga aagaccagaa cttgtacatg gattcatagt attctgcata
    16021 ttgtgaaggc atctgtgcct tattcatttt tgaatagtcc accaagaact tcttcaacat
    16081 atccttatca aacgcaccgg tctgaggatt acggaacgga gtctgttgca gcatcggatg
    16141 cacaccggca ttaatgatag cctgaatctc agccttcgat acaaccagac cgagtttctt
    16201 tgcttccttt tcaatcagct tattattgac gtatgttctc catacttcat ctttgatttg
    16261 gtttgtctgc tcatcgctca atgcactgtt gccactggag aacttgatga cttctgtata
    16321 ttcttctacc aatgcttgaa aatcctgagc ggaaattgat tccccgttca cttcacctac
    16381 gtcttgtgac tggtgtggct gaagcacttt ccacgcgtca cctgcgatga aagcaaacag
    16441 cgc
//
