LOCUS       gnlProkkaPPMDHLBH_4    21589 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PPMDHLBH_4.
ACCESSION   gnlProkkaPPMDHLBH_4
VERSION     gnlProkkaPPMDHLBH_4
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-02 07:40:42
            Original ID  :: gnl|Prokka|PPMDHLBH_4
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 2334
            Orig. end    :: 23923
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..21589
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:11589]"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11589
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     cand_cluster    1..21589
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..21589
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /tool="antismash"
     CDS             589..1539
                     /locus_tag="ctg4_4"
                     /transl_table=11
                     /translation="MQKDYETFVEKLEIGIYEATGIPRENISFEKEGGRFAPVGDRLLV
                     KFAEHDDAWEVCGLYTQELFKSYQNGSPFEEIIKEITDDLNRIKKADIYEKTRVIRDYE
                     KTKPRLFIRLLNADKYSADLQDAVYKTLGDIALVLYMKVTEYEGCVTSTKIRQGMLEQW
                     GKECDEVFKEAILNTYFMSPPRIYRWEQMIFNPEYEGESFMNLGDKCELKKDAMGNCLS
                     TTKKTNGAVAVFLPGVAEQLAYMLDSDFYMVFTSVHEVMIHNDKFVEPEDLQCVLRDTI
                     REATPKEDYLTSRIYQYNRETHKFICVTPLEKDEK"
     CDS             complement(1614..2408)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 168.4; E-value:
                     3.5e-51)"
                     /gene_kind="transport"
                     /locus_tag="ctg4_5"
                     /transl_table=11
                     /translation="MLELKNIYKTFNPGTINEKRALNGLNLKLNEGDFVTVIGGNGAGK
                     STMLNAVAGTWPVDEGQILIDNIDVTKLSEHKRATYLGRVFQDPMTGTAATMGIEENLA
                     LAKRRGKSRLLRSGITKAEREEYKELLKILGLGLEDRLTSKVGLLSGGQRQALTLLMAT
                     LQKPKLLLLDEHTAALDPKTAAKVLEITDMIVNRDHLTTLMITHNMKDAIAHGNRLIMM
                     MEGKIILDIQGEEKKKLTVKNLLDQFEKASGEEFSNDSALLG"
     CDS             complement(2411..3328)
                     /gene_functions="transport (smcogs)
                     SMCOG1113:inner-membrane translocator (Score: 68; E-value:
                     1.2e-20)"
                     /gene_kind="transport"
                     /locus_tag="ctg4_6"
                     /transl_table=11
                     /translation="MQILTLITALPGAVAQGLIWGIMAIGVYITFRILDIADLTVDGTM
                     CTGGAVCIMMMLSGHNVWISMLAATLAGMLAGLVTGIFHTFMGIPAILAGILTQLSLYS
                     VNLKIMGKANQAINVDKYNLLVSLRHIKNASLSKNTIFIVAVMCILLIAILYWFFGTEL
                     GCSLRATGCNPNMSRAQGINTNRNKVLGLMISNGLVGLSSALLAQYQGFADVNMGRGSI
                     VIGLAAVIIGEAIFGRIFRNFALRLLAVIFGSILYYLVLQIVIWMGIDTDLLKMLSAIV
                     VALFLAFPYWKGKYFNKPAKRGGK"
     CDS             complement(3479..4465)
                     /locus_tag="ctg4_7"
                     /transl_table=11
                     /translation="MKRKALAITLAAAMAMGTCAVTASAADGDKYTIGICQLVQHEALD
                     AATQGFKDEVTKELGEDAVTFDEQNAQGDSNTCSTIINSFVSNNVDLILANATPALQAA
                     AAGTSDIPILGTSVTEYGVALGLDDFDGTVGGNISGTADLAPLDQQAAMLNELFPDAKN
                     VGLLYCSAEANSQYQVDTVKAELEKLGYTCEYYAFSDSNDLSSVATTATDASDVIYVPT
                     DNTVASNTEIINNICLPAKVPVITGEEGICSGCGVATLSISYYDLGVTTGKMAVKILKD
                     GEDISTMPIEYAPNFTKEYNKDICEELGIEVPDDYVAIGEAAEETAK"
     CDS             4729..5493
                     /locus_tag="ctg4_8"
                     /transl_table=11
                     /translation="MAYSIMLDAGHGGQDPGAVYKGRQEKNDNLKLALAVGEILKNKGI
                     DISYTRTGDVYQTPFEKAQLANQAGVDYFISFHRNSSPKENQYNGAEVLIYDKSGIKYQ
                     MAENILGALGEVGFREIGVKERPGLVVLRRTRMPALLIETGFINSEEDNKLFDNKFSDI
                     AQGIADAILGSLDEETVQEPLYYRVQTGAFRKKENADRMLYQLLEKGYPSFMLHENGLY
                     KVQTGAYQQIGNAVNMEQRLRDDGYSTVIVTK"
     CDS             5788..6387
                     /locus_tag="ctg4_9"
                     /transl_table=11
                     /translation="MNDVYEKFLKSSEEFIFAENKPEKSDIIFVPGNGYPQMAEKAAEL
                     FKKGMADWILPSGKYSVVNGKFSGVLEKSNVYNKEYGTEWEFLRDVLIKNGVPDQKILK
                     EDQATFTYENAIYSRQVTDHAELEIERAILCCKSYHARRCLMYYQLLYPKTEFYVVPVN
                     ADGITRENWRKNEEGIDAVTGELSRIVKQFSLMLER"
     CDS             complement(6391..7674)
                     /gene_functions="other (smcogs) SMCOG1273:hypothetical
                     protein (Score: 354.6; E-value: 1.3e-107)"
                     /gene_kind="other"
                     /locus_tag="ctg4_10"
                     /transl_table=11
                     /translation="MDSSIAFQAVAILILIALSSFFSSAETAMTTVNKIRIQSLAEQGN
                     KRAVILEKIISDSPKMLSTVLIGNNIVNMSVSSLMTTLTIKILGNAYVGITTGILTLLI
                     LIFGEITPKNLATIHAEKLSLAYSRIIYGLMILLTPVVFIVNKITEGVLVILHVNPDEK
                     ANAMTEHELRTLVNVGEKDGVIENEEKQMIYNVFDFGDSTAKDVMIPRIDMTFIDINFS
                     YDELMAVFSEDMHTRFPVYEDNTDNVIGIINMKDLLVYPKNKPFSIRNILREPYFTYEY
                     KATADLMIEMRKASVNLAIVLDEYGATAGLVTLEDLLEEIVGEIRDEYDEDEVEDIKEI
                     QPEREYVVQGSAKLDDINEALHINLESEDYDSIGGYIIEQLDCLPKEGQSVTLESGIRL
                     VVDRLDKNRIELVHIWLPEKKTETEEQP"
     CDS             8019..9527
                     /locus_tag="ctg4_11"
                     /transl_table=11
                     /translation="MSNNINRIRKNKLKGTGIFAAAALTAALIAGNNIPGVTRQVSAAE
                     SQENTVSSLIPDNITLDKPVELADVELPATEYGTFEWADGSFVPAQRVQSCEVLLIPAE
                     GQDLSHVDGWDPESGAVVGYINVIVNSITDSDNSDKTEGSGKTDPTENADPTETPETSS
                     EKPAADENADTDNKEDKESKSDQDNQTDTDNEENKIEEDKTDNKNNKDNNSNADKTDKD
                     TETTGKLEPADDMTQDKEDTKKDDEDGAGDNIFDNPVLPDDKDDRPTDAEDSLSDEEKE
                     ERAALNHTCDGITVSGVNLPWYVQFRVSSGDSYQFTNESDAMIFQSYEFELWDLKNNTE
                     YEIPNGDYISVTVPVKSGYQYTIEHLLDNGATETIIPSVENGIMVFSTHSFSPFGIAGS
                     RQLVGPDAGNDTDDTDAVTPAPASSDSQSPDSGKNNTVSMNDSSDSNNGSSSDQNDNLT
                     ENKAVKNNNTVNTGDTTSIMPFVILFVAAAVIAGVVVFIKKRKK"
     CDS             9577..9927
                     /locus_tag="ctg4_12"
                     /transl_table=11
                     /translation="MKVRAILKSLLFAYALTGVALLLLALVLFAFDLGETAVDAGIIII
                     YVLACFMGGFMAGRIVRKDKYLWGVITGLAYYVLLLTVSVMAKGGWDMSAAHAVTTFFM
                     CTGGGTLGGMLS"
     CDS             10001..10141
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR03973"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SCIFF"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_13"
                     /sec_met_domain="TIGR03973 (E-value: 7.8e-28, bitscore:
                     87.3, seeds: 29, tool: rule-based-clusters)"
                     /sec_met_domain="SCIFF (E-value: 9.9e-28, bitscore: 87.0,
                     seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEHIKTLNTKNLQNTVKKGGCGECQTSCQSACKTSCTVGNQSCEQ
                     K"
     CDS             10222..11589
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Ranthipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_14"
                     /sec_met_domain="Ranthipeptide_rSAM_RRE (E-value: 3.8e-29,
                     bitscore: 92.0, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 2.6e-16, bitscore: 51.3,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 2.2e-14, bitscore: 45.3,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 5.7e-20, bitscore:
                     62.7, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLIHRYKSNGFNIVLDINSGCIHLVDEVTYEVLPYLEEGLGTEA
                     IAEKLENKYNREDIETSVRECNKLKEDGMLFTKDVYENVIEEFSNNRQTVVKALCLHIA
                     HDCNLACRYCFAEEGEYHGRRALMSYEVGKKALDFLIANSGSRKNLEVDFFGGEPLMNW
                     QVVKDLVKYGREQEKLHNKKFRFTLTTNGVLLNDEVMEFCNKEMGNVVLSVDGRKEVHD
                     YMRPFRKGAGSYDLIMPKFQKFAESRNQDKYYVRGTFTHHNLDFSKDVLHLADLGFKQI
                     SVEPVVAADTEEYAIREEDIPQIMEEYDTLAKEMIKREKEGKGFNFFHFMIDLTGGPCV
                     YKRLSGCGSGTEYLAVTPWGDFYPCHQFVGEEQYLMGNVDEGITKPEIQKEFGGCNVYT
                     KKDCKDCFARFYCSGGCAANAFHFQGDIKGNYEIGCELQRKRVECAIMIKAALACD"
     CDS             11701..14109
                     /locus_tag="ctg4_15"
                     /transl_table=11
                     /translation="MKKSKGIVVLLLTLILTVFFCFTAAVGIGPTGTGAAKHINTGLDL
                     AGGVSITYQAKESNPTSEEMSDTIYKLQKRVEQYSTEAQVYQEGSDRITVEIPGVTDAD
                     TILNDLGKPGSLYFITKEDADGNQNFTTGQDGYVLSRTMDEIKESGSVVLEGSDVADAQ
                     GGAIQNQNTSAKEYVVSLTLTSDGENSGKTKFAEATKNNVGKQIAIVYDNNIISAPNVN
                     EEISGGKAQISGMSDLEEAQNLASYIRIGSLGLELEELRSSVVAAQLGEEAISTSVLAG
                     AIGLIIVIIFMIIAYRIPGIVAGIALILYTSLMLITLNAFDITLTLPGIAGIILGIGMA
                     VDANVIIYARIREEIGAGVSVRNSIKSGFSKAFSAIFDGNITTLIAAFVLMWLGSGTVK
                     GFAYTLALGIVISMFTALVVSRLIVNALYAVGVRDPKFYGSAKERKAVDFLGKKKVFLA
                     ISIILILCGPAAMFANSHAGNKALNYSLEFSGGTSTTVTFNEDMDIKTIDSEVTPVVEE
                     VTGDKNVQPTKVVGTNQVVIKTRSLNQSEREALQSALVEKFGVDDSTISTESISSTVSS
                     EMRRDAIVAVIVATICMLLYIWFRFKDIRFASSAVLALLHDVLVVLAFYAIARVSVGNT
                     FIACMLTIVGYSINATIVIFDRIRENLHSGSREKLAEIVNTSITQTLTRSIYTSFTTFV
                     MVAVLYIMGVSSIREFAAPLMVGVLVGAYSSVCITGALWYVMKKKFAGKGQPAIAAASA
                     SAKSSSKPKKARDVSQKDPTQPKKKNRKRVAERLAAEEAAKKQQNDDAE"
     CDS             14191..15903
                     /locus_tag="ctg4_16"
                     /transl_table=11
                     /translation="MEKWVIAAKRADFNQIGQQFHIDPVIARLIRNRDVIGEDKIREYL
                     SGTVQELPSPWLMKDMEKAVDILEKKISQKAKVRIIGDYDIDGVTSTYILMKGLARIGA
                     DVDTYIPDRVADGYGIHAHLIERAETDRIDTIVTCDNGIAAAAEIQMAKDKGMTVIITD
                     HHEVPYREEKGERQMVLPPADAILNPKQYDCPYPNKNLCGAVVAFKYITALYERFGVPA
                     EELEDYYELAAIATVGDVMDLQGENRILVKEGLCRLKNTKNQGLQELIRANSLEDAKIT
                     AYHIGFVLGPCINASGRLDTAARSLALLNAKTKEEAARLAGDLTALNQSRKALTEKGKE
                     EAIRIIETTELKNDRVLVVYLPDCHESLAGIIAGRIREKYHRPAFVLTGGETSAKGSGR
                     SIESYSMYEELVKCADLMIQFGGHPMAAGLSIEEKNIEEFRRRLNVNCTLTDEELRPKI
                     VIDVPMPVSYITKELVEQISLLEPFGKGNTKPVFAQKNLRVLDYSIIGKNKNVVKLKLL
                     DPQGISMEGIYFGEAEDFVNFIREKDSISVTYYPEINRFRGRESLQIIIQNYC"
     CDS             16051..16575
                     /locus_tag="ctg4_17"
                     /transl_table=11
                     /translation="MKKIEDYVLSIPDFPEPGIIFRDITSVLQDADGLQLAIDSMQDCL
                     KDIDVDVIAGTESRGFIFGVPIAYNLHKPFVPIRKKGKLPRETVSVSYDLEYGSAEIEM
                     HKDSIKPGQKVVIVDDLIATGGTIEAAIKLVEQLGGEVVKVVFLMELAGLKGRERLNGY
                     DVASVICYDGK"
     CDS             16613..18943
                     /locus_tag="ctg4_18"
                     /transl_table=11
                     /translation="MTEVTKSTEAKKDEMQVEKEKLESVKRADAAVKTMHDFTSPEVLY
                     KELINSVLKYHPSTDISMIEKAYKVASEAHEGQKRKSGEPYIIHPLCVAIILADLELDK
                     ETIVAGLLHDAVEDTWMTYEEVEKEFGSEVALLVDGVTKLGQLSYSADKVEVQAENLRK
                     MFLAMAKDIRVILIKLADRLHNMRTLQYMRPEKQQEKARETMDIYAPIAMRLGISKIKV
                     ELDDLSLKYLKPDVYYDLVHKVALRKSEREQFVGAIVKEVKKHMDDANIKAQVDGRVKH
                     FFSIYKKMVNQDKTIDQIYDLFAVRILVDTVKDCYAALGVIHEMYKPIPGRFKDYIAMP
                     KPNMYQSLHTTLIGPNGQPFEIQIRTYEMHRTAEYGIAAHWKYKESSDGKAPVGKSEEE
                     KLNWLRQILEWQRDMSDNKEFMSLLKNDLDLFADSVYCFTPQGDVKTLPSGSTPVDFAY
                     SVHSAVGNKMVGARVNGKLVPIEYEIKNGDRIEIITSQNSQGPSRDWLKLVKSTQAKNK
                     INQWFKKELKEDNILKGKEMLAQYARAKGFKIANYTKNQYLEAVLRKYGFRDWDSVLAA
                     IGHGGLKEGQVFNKLVEAYDKENKKNLTDEQVLEAASETQEKLHIAKSKSGIVVKGIHD
                     VAVRFSKCCNPIPGDEIVGFVTRGRGITIHRTDCVNVLNMSETDRTRLIEAEWQQPDTK
                     EKEKYMAEIQVYANNRTGLLVDLSKIFTERKIDLRSINSRTSKQEKATISMSFEIGSKE
                     ELRSLIEKIRQVESVIDVERTTG"
     CDS             19008..19637
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1170:metallo-beta-lactamase family protein (Score:
                     162.3; E-value: 1.7e-49)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_19"
                     /transl_table=11
                     /translation="MKNLELQKCILGPVYTNCYILKNKETGELIIVDPADCPEKIEMKI
                     SRMNGKPVAILLTHGHFDHILAAQAVKEKYNIPIYACRQEEEMLREPSINMTVHYGQGC
                     SIVPDVFLEDLDVIRLAGFSVQMIHTPGHTKGSCCYYLKDEGVLFSGDTVFYGSVGRTD
                     FPGGSTAEIVRSLHKLVDSLPEETEVFPGHDASTTIGYEKRYNPFV"
     CDS             19630..21144
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_20"
                     /sec_met_domain="PF04055 (E-value: 1.3e-24, bitscore: 78.5,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCKIGILFKNRDFEHDVYELIKAFYPEAEIHTLYENAEAEYDLRF
                     SVERDNDSYIIKYERTENLSKQETEQKGVISADILSKENAGCGIQDAHALRKENKDNIK
                     YALYQLLVKLTGRTLPWGNLTGIRPAKLAMGMIESGMKNTEAAREMRERYLVSPQKTAL
                     AITIANREREILKDIDYENGYSLYIGIPFCPSICLYCSFSSYPLKVWEKRTDEYVEALC
                     REVRETALMMKGRKLDTIYIGGGTPTTLLPHQIRKLLDTVGEAFGYEGLAEFTVEAGRP
                     DSITREKLMAIREYPVTRISVNPQTMNQETLDIIGRRHTVEQTKEAFHLARELGYDNIN
                     MDLIVGLPGEDIHMVERTLEQVRELAPDSITVHSLAVKRAARLNIFKEKYQEMSFENNQ
                     EIMDLTMKTAYEMGMSPYYLYRQKNMKGNFENVGYAKVDKAGIYNILIMEEKQPIIALG
                     AGGSSKLVFDHGQRIERVENVKDVSNYISRIDEMIERKRTAIATWL"
ORIGIN
        1 taaagacatg gtttctaaac aaggtctttc agaccgattt tatattgcat ctgctgcaac
       61 cagcactgag gagatatgga atggaatcgg gaatccggta tatcctccgg cgcgagagga
      121 gcttgctaag catgggattg attgtaaggg taagcgcgca gttcaactaa cgaaggcaga
      181 ttatgataaa tatgattata ttctcggtat ggattactgg aatctgaaga atatgttaag
      241 aatattgaaa tcggatccag aggacaaggt taagcttctt ctggattata gtggtgatcc
      301 gagggatatc gcagatccat ggtatacagg tggatttgat gtcacatatt cggatgtggt
      361 ggagggctgt gaggcttttc tggaatatct gaaagataaa aagaaactgt aataaatatt
      421 gtcgatgaaa tttactttac aaatagctgt ggctatttta tactatgtct acagcgactc
      481 ttaagggggc tttcgctccc ttattttctt ttttccgaaa acggaaagtc aacattcaaa
      541 tcagggcatc ctgcccgtat tattttcaaa gcaagaaagg aactgaatat gcagaaagac
      601 tatgaaacat tcgtagagaa actggagatt ggtatttacg aggctacagg gattccgagg
      661 gaaaatattt cttttgagaa agaaggcggg aggtttgcgc ctgtaggaga cagactgctg
      721 gtgaagtttg cagagcatga tgatgcctgg gaggtctgtg gactttatac acaggaactt
      781 tttaaatctt atcagaatgg cagtccgttt gaggaaatta taaaagaaat cacagatgat
      841 ctgaatcgga taaaaaaggc ggatatttat gagaaaacaa gagtgatcag ggattatgag
      901 aagacaaaac cccgcctgtt tataagattg ctgaatgcag ataaatattc cgcggatctt
      961 caggatgcgg tgtataaaac tcttggtgat attgcacttg tgctttatat gaaagttacg
     1021 gaatatgaag gatgtgtgac aagtacaaaa atccggcagg gaatgctgga acagtggggg
     1081 aaagaatgtg atgaagtgtt taaggaggcg attctcaata cgtatttcat gagtccgcca
     1141 agaatttaca gatgggaaca gatgattttt aatccggaat atgaaggtga aagttttatg
     1201 aatctgggtg ataagtgtga attgaagaaa gatgcaatgg gaaattgtct cagtacaacg
     1261 aagaaaacaa atggtgcagt tgcagtgttc ctgccgggag tggcagaaca attggcatat
     1321 atgctggatt ccgatttcta tatggtgttt accagtgtac atgaggtaat gatccacaat
     1381 gataaatttg tagaacctga agatttgcag tgtgttttgc gggatacgat cagggaggct
     1441 acaccgaaag aggactatct gacgtcgaga atctaccagt acaataggga aacacataaa
     1501 tttatctgtg taactccgct ggaaaaagat gagaaataaa aatatgagag tactccataa
     1561 aaaagtactc tcatataaag gatatttaga aacgttatga gtaatttata cggttatccg
     1621 agcagtgcag agtcattgct gaactcttct ccgcttgctt tttcaaactg atccagaagg
     1681 tttttaactg tcagtttttt cttttcttct ccctggatat ccagaatgat ttttccttcc
     1741 atcatcatga tcagacgatt gccatgtgca atagcgtcct tcatgttgtg ggtgatcatc
     1801 aatgtcgtga ggtgatcgcg gtttacgatc atatctgtaa tttccagaac tttggcagct
     1861 gtttttggat caagagctgc ggtatgttca tccagaagca gaagctttgg tttctgaagc
     1921 gttgccatca gaagagtaag agcctgtctc tgaccacccg agagaagtcc tactttagaa
     1981 gtcagtctgt cttccagacc aagaccaaga attttcagga gctctttgta ttcttcgcgc
     2041 tcagctttag tgattccgga gcggagaaga cgggattttc cgcggcgttt tgcaagtgca
     2101 aggttttcct cgatacccat tgttgcagcg gttcctgtca ttggatcctg aaacacacgt
     2161 ccaaggtatg tagcacgttt atgttcagaa agttttgtaa catcaatatt gtcgataagg
     2221 atctgtcctt catcaaccgg ccaggttcct gcaacagcat ttagcatagt agatttgccg
     2281 gcgccgtttc ctccgataac agttacaaaa tcgccttcgt tcagcttcag gttcagacca
     2341 tttaatgcac gtttctcatt aatggttccg ggattaaagg ttttatagat atttttaagt
     2401 tcaagcattt ttatttacct ccccttttgg ctggtttatt aaagtatttg cctttccagt
     2461 atgggaatgc aaggaagaga gcaactacga ttgcggacag catcttcagc aggtcagtgt
     2521 cgatacccat ccagataaca atctgaagta ccagataata cagaatggaa ccgaagataa
     2581 ctgctaacaa gcgaagggca aagttgcgga aaatacgtcc aaagattgcc tcgccaataa
     2641 taactgctgc cagaccgata acgatggaac cacgtcccat gttgacatct gcaaatccct
     2701 gatactgtgc aaggagtgca ctggaaagtc ctaccagacc gttggaaatc ataagtccga
     2761 gaactttatt cctgtttgtg ttgataccct gggcgcgtga catatttggg ttacatccgg
     2821 ttgcgcgaag ggaacagcca agctctgttc caaagaacca gtagagaatg gcaatcagga
     2881 gaatacacat aactgctaca ataaaaattg tgtttttgga aagagatgca ttttttatat
     2941 gtcgcaggga aaccagaaga ttatatttat caacgttgat tgcctgattt gcttttccca
     3001 tgatcttcag gtttacggaa tacagagata actgtgtcag gattccggca aggattgcgg
     3061 gaattcccat aaaggtgtga aaaattccgg tcacaaggcc tgccagcatt ccggcgagag
     3121 tagcggccaa catagaaatc cagacattat gaccggaaag catcatcata atacacactg
     3181 caccaccggt gcacatagtg ccatcaactg taaggtctgc aatatcaaga atacggaaag
     3241 tgatataaac accgattgcc ataattcccc agatcagacc ctgggctact gcacccggaa
     3301 gtgcagtgat taatgttaaa atttgcattt gtaatttcct cctgttgaga tgcgaaaagc
     3361 gagagaggcg tcaaaccttt cccgctgatc gcatataaat tgaatttttt ataactgttt
     3421 gataagctgt tatttaaaat cctgttggtg tgagtatttt tcaactgtct gaccggattt
     3481 atttggcagt ttcttcagca gcctcgccga ttgcaacata atcgtccgga acttcgatgc
     3541 ccagctcttc gcagatatct ttgttatatt cttttgtgaa gtttggtgca tattcgatcg
     3601 gcattgtgga aatatcttca ccgtccttta aaatcttaac agccatctta ccggttgtaa
     3661 caccaaggtc ataatagctg atggaaagtg tcgcaacacc gcatccgctg cagatacctt
     3721 cttcgcctgt gattaccgga acttttgccg gaaggcagat gttgttgatg atctctgtgt
     3781 tggaagcaac tgtattatct gtcggtacat aaattacatc acttgcgtca gttgctgttg
     3841 tagcaacaga agagagatca ttagagtcag agaatgcata atattcacat gtatatccga
     3901 gtttttcaag ttcagctttt actgtatcta cctgatactg agagtttgct tcggcagaac
     3961 agtagagaag acctacattt tttgcatccg ggaaaagttc attgagcatt gctgcctgtt
     4021 gatcaagggg agcaaggtct gcagttccgg aaatatttcc gcccacagtc ccgtcgaaat
     4081 catccagtcc aagtgcaaca ccgtattcag taacagaagt accaagaatc ggaatatcgc
     4141 ttgtccctgc tgcagctgcc tgaagagcag gagttgcatt tgcaagaatc aggtcaacat
     4201 tattggaaac gaagctgtta atgattgtag aacaggtgtt ggaatctccc tgtgcgttct
     4261 gctcgtcaaa ggtaactgcg tcttctccca gttctttggt gacttcatcc ttgaatccct
     4321 gtgtcgcagc gtcgagagct tcgtgctgta caagctgaca gataccgatt gtatatttgt
     4381 ctccgtcagc agcacttgct gttactgcgc aggttcccat agccatggct gctgcaagag
     4441 tgattgctaa tgcttttctt ttcataatga tatatcctcc taatataatg tttaaattaa
     4501 gtcaggtaag aattgcgttt attatttgat aatataaaac ttacctgaat ccgaaagatt
     4561 ttctgcaggg aaagcagtac tggtaaatga ttcggataat gtcatcggac tattcgacta
     4621 tgacgtttta aagtataacg ctttagtgtg aaaaagtcaa gcgacctgca caattatatt
     4681 tttaattcat atagtataaa gagtatatga agaaagcaga gtgtcgtcat ggcatattcg
     4741 atcatgctgg atgccggaca tggaggtcag gatccgggag ccgtatataa gggaagacag
     4801 gaaaagaatg acaatcttaa acttgctctt gcggtaggtg agattttaaa aaataaaggg
     4861 attgatatct cttatacccg taccggtgat gtctatcaga caccttttga gaaggcacag
     4921 cttgcaaatc aggcaggagt agattacttt atttcatttc atcgaaacag cagcccaaag
     4981 gaaaatcagt ataatggagc ggaagttctg atttatgata aaagcgggat taaatatcag
     5041 atggctgaga atattctggg agctctggga gaagtgggat tccgcgaaat cggtgtaaaa
     5101 gagcggccgg gacttgtggt cctcagacga accaggatgc cggctctttt aatagaaacc
     5161 ggatttatca attctgaaga agataataaa ctgtttgata acaagtttag cgatatagct
     5221 cagggaattg cagatgcgat tcttggaagc ctggatgagg aaacagtgca ggaaccgctt
     5281 tattacagag tgcagactgg agcgttcaga aaaaaagaga atgcggaccg tatgttatat
     5341 cagttactgg aaaaaggtta tccctctttt atgttacatg aaaacggatt gtataaagtt
     5401 cagacaggtg cctatcagca gattggtaat gcagtaaata tggagcagag actgagggat
     5461 gatggttaca gtacggttat tgtgacaaaa tagctttctg gaaatattgg aagtctgcgg
     5521 attttttgtt taaccgaatc aaataagtcc cctgcggagg ttgcgaaaag caataagtag
     5581 tgggggacat agttttaaga attaacttgg ttgtacgttg atagaaaaaa tatggtacac
     5641 tgtatctatc tatagaaatt ccatagaaat cttcgtaaat aatgcatatt gttccggctc
     5701 atcagagcgt gaaattctgt tggactgtta caaacgcatt atttgagagg tgctgtagaa
     5761 aaaacagata acgaggagtt agtaatgatg aatgacgtat atgaaaaatt tttaaaaagt
     5821 tcagaagagt ttatttttgc agaaaacaag ccggaaaaat ctgatattat ttttgtccct
     5881 ggaaatggtt atccgcagat ggcagaaaaa gcagcagaat tgtttaagaa agggatggcg
     5941 gactggattc tgcccagtgg aaaatacagc gtagtaaatg gaaagttttc aggcgttctt
     6001 gaaaaaagca atgtatataa taaggaatat ggaacagaat gggaatttct cagggatgtt
     6061 cttataaaaa acggagttcc ggatcagaaa atcctgaaag aagatcaggc aacctttact
     6121 tatgagaacg caatttattc cagacaggtg acagatcatg cagaactgga aatagaaaga
     6181 gcgattttgt gctgcaaatc ttaccatgca agaagatgtc tgatgtatta tcagctcttg
     6241 tatccgaaaa cagaatttta tgtggtgcct gtgaatgcag atggaattac cagagaaaac
     6301 tggagaaaga acgaagaagg aattgatgcg gttacaggag aactctccag aatcgtgaaa
     6361 caattttcac tgatgctgga gagatgacag ttacggctgt tcttctgttt cggttttctt
     6421 ctcgggaagc cagatgtgga caagttcgat tctgtttttg tccagacggt caacaaccag
     6481 gcggatgcca ctttcaagtg tgacagactg accctctttg ggaaggcagt caagctgttc
     6541 aataatatat ccgccaatag agtcataatc ttcagattcc agattaatat ggagggcttc
     6601 gttgatatca tccagcttgg cagaaccctg aacaacatat tctctttcag gctggatttc
     6661 tttaatatct tcgacttcat cctcatcgta ttcgtcgcga atctcaccta caatctcttc
     6721 caataggtct tccaatgtga ccagaccggc tgtggcaccg tattcgtcca gaacgattgc
     6781 cagattgacg gatgctttac gcatttcgat catcaggtct gctgtagctt tgtattcata
     6841 ggtaaaataa ggctcacgca ggatgttgcg gattgaaaaa ggtttgttct ttggataaac
     6901 aagaagatct ttcatattga taataccgat tacgttatca gtgttgtcct cataaaccgg
     6961 aaaacgggta tgcatatctt cactgaagac cgccataagt tcatcatagg aaaaattgat
     7021 atctataaag gtcatgtcga ttctgggaat catgacatct tttgcagttg aatcgccaaa
     7081 atcaaacaca ttgtagatca tctgtttttc ttcgttttca atgacgccgt ctttttcacc
     7141 tacattgacg agggtacgca gttcatgttc agtcatggca tttgcctttt cgtccgggtt
     7201 aacatgcaga atgaccagta caccttctgt tattttattt acaatgaaaa caacgggagt
     7261 aaggagaatc ataagcccgt atattattct tgaataggcc agggacaatt tttcagcatg
     7321 gattgttgcc aggtttttgg gggttatctc accgaaaatg agaatcagca gagtcaggat
     7381 gccggttgtg attcctacat atgcgtttcc cagaatcttt atggtgagtg tagtcatgag
     7441 agaagaaaca gacatattta caatgttgtt tccgattaat acggtactga gcatctttgg
     7501 agaatcggaa attatttttt ccagaataac agcacgtttg ttgccctgct cggcaagaga
     7561 ctgtatccga attttattta cggttgtcat agcggtttcc gcagaagaaa aaaatgaaga
     7621 aagtgcgatc agtatcagaa tcgccaccgc ctgaaaggca atacttgaat ccaagattta
     7681 ttcactcctt ttgattattt ttttattgat tgaatcatat cataaaacat ttaagcaaaa
     7741 tatacatgat ttcatataaa aaatcaagaa aaagcttttg gttcaaagat agtataaaaa
     7801 aatttaaaag aggactgtcg aaaaagtaag atttgtgtta taattcactc gattaaaatg
     7861 aaaaaaaaca ttacagaata tttacaaaat gataaaagtt tgataatata cagatatgta
     7921 atattattgt attacgtaaa aaagaactga tatttggctg aaagtaaaaa atgattatca
     7981 ggaaacataa gaatcgaata taaatataga ggtgcgatat gtccaataat ataaatagaa
     8041 taagaaaaaa taaattaaaa ggaacgggta tttttgcggc agcggcttta acagcggctt
     8101 tgattgcagg aaataatata ccgggtgtaa caagacaggt cagtgcggct gagtcacagg
     8161 agaatactgt gtcttctctg atcccggaca acatcacgct tgataagcca gtagaacttg
     8221 cggatgtaga acttccggca acggaatatg gaacttttga atgggcagat ggaagtttcg
     8281 ttcctgcaca gcgtgtacag agctgtgagg tacttcttat accggcagaa ggacaggatt
     8341 taagccatgt ggatggatgg gatccggaga gcggcgcggt tgtcggttac atcaatgtaa
     8401 tagtgaacag tattacggat agtgataatt ctgataagac agaaggctca ggtaaaacag
     8461 atccaacaga aaatgcagat ccaacagaaa cgcctgaaac ttcgtcagaa aaacctgccg
     8521 cagatgaaaa cgctgataca gacaataaag aagataagga aagtaaatca gatcaggata
     8581 atcaaactga tacagacaat gaagagaata agattgaaga agataaaaca gataataaaa
     8641 acaacaaaga taataacagc aatgcagata agacggataa agatacagaa actaccggta
     8701 agctggaacc tgcagatgat atgacacagg ataaagaaga tacgaagaaa gatgatgaag
     8761 atggcgcagg tgataatatc tttgataatc ctgttctgcc ggacgataag gatgaccgtc
     8821 ctacagatgc agaggattct ctttctgatg aagaaaaaga agagagggcc gcacttaatc
     8881 atacctgcga cggtattaca gtaagcggag ttaatcttcc atggtatgta cagttcagag
     8941 tttcaagcgg tgacagctat cagtttacca atgaatcaga tgcaatgatt ttccagtctt
     9001 atgaatttga actctgggat cttaagaata atacagaata tgagatccct aatggagatt
     9061 atatcagtgt cactgtgccg gtaaaatccg gatatcagta tactatcgaa catctcctgg
     9121 ataacggggc aactgagacg attattccga gtgtagagaa tggtattatg gtattcagca
     9181 cacattcttt cagtccattt ggaattgcag gaagcagaca attagtagga cctgatgcgg
     9241 ggaatgatac ggacgacaca gatgcggtaa ctcctgcacc ggcttcctcc gacagtcaga
     9301 gtcctgattc cggaaagaac aatacagtat ctatgaatga cagttctgac agcaataatg
     9361 gttcttcttc tgatcagaat gataatttaa cggaaaataa agctgtgaaa aataacaata
     9421 cagtaaatac cggagataca acatcaatta tgccgtttgt gatactgttt gtggcagctg
     9481 cagtgatcgc cggtgtggtt gtatttataa aaaagagaaa gaaataaaag aataacactg
     9541 attcctcccc catatagttt aacaggaggg gaagcaatga aagtcagagc aattttgaaa
     9601 tcactattat ttgcatatgc attaacagga gtggcattac tgcttttggc cctggtactg
     9661 tttgcttttg atctgggaga aacagctgta gatgcgggga ttattataat ttatgtactt
     9721 gcatgtttca tgggaggttt tatggccggc agaattgtgc gtaaagacaa atatctgtgg
     9781 ggtgttatca caggtctggc ttactatgta ttactgttga ctgtctctgt tatggcaaaa
     9841 ggcggctggg atatgagtgc agcgcatgca gttacaacat tttttatgtg cacaggcggc
     9901 ggaacactgg gtggaatgct gtcgtaaaaa aaagctttta aaatgaaaag atatatgata
     9961 tactatgcca agaatataat tacataagga ggatagagtt atggaacata tcaaaaccct
    10021 gaatacaaag aatttacaga acactgtaaa aaaaggtgga tgtggcgagt gccagacttc
    10081 ctgccagtcc gcatgtaaaa cttcctgtac agtaggaaac cagagctgcg agcagaaata
    10141 agatcagcta tggagaaatg agataagcag cggaactttt attccgctgc ttatcttacg
    10201 cttagaaagg attttagtaa aatgagtctg attcaccgtt ataaaagcaa tggctttaat
    10261 attgtactgg atatcaacag tggatgcatc catctggtag atgaggttac atatgaggtt
    10321 cttccatatc tggaagaggg ccttggcaca gaagctattg cagagaaact ggaaaacaaa
    10381 tataacagag aagatattga gacatctgta agagaatgta ataagctgaa agaagatgga
    10441 atgcttttta caaaagatgt ttatgagaat gtaattgaag aattttcaaa taaccggcag
    10501 accgttgtaa aagcattgtg cctgcacatt gctcatgact gcaatctggc ctgccgttat
    10561 tgttttgccg aagaaggcga atatcatggc agaagagctc ttatgtccta tgaagtcggc
    10621 aaaaaagctc ttgatttcct gatcgcgaac tccggttcca gaaaaaacct ggaagtagat
    10681 ttctttggcg gcgagccgct gatgaactgg caggttgtaa aagatctggt aaaatatggc
    10741 agagagcagg aaaagcttca caataagaaa ttccgtttca ctttaacaac aaacggagtt
    10801 cttctgaatg atgaagtaat ggaattctgc aataaagaga tgggcaacgt tgtactgagt
    10861 gtggacggac gtaaggaagt acatgactac atgcgtccat tcagaaaagg tgcaggaagc
    10921 tatgacctga tcatgccgaa gttccagaag tttgcagaat ccagaaatca ggacaagtat
    10981 tatgtaagag gtacttttac ccaccataat cttgatttct ccaaggatgt gcttcatctg
    11041 gcagatcttg gatttaaaca gatttccgta gagcctgtag ttgcggctga tacggaggaa
    11101 tatgcgatcc gtgaggagga tatcccccag atcatggaag agtatgatac tcttgcaaaa
    11161 gaaatgatta aaagagagaa agaggggaaa ggatttaact tcttccattt tatgatcgac
    11221 cttacaggtg gcccttgtgt atacaagaga ctgtcaggct gcggttcagg aacagagtac
    11281 ctggctgtaa caccctgggg tgatttttac ccatgtcacc agtttgttgg tgaagaacag
    11341 tatctcatgg ggaatgtaga cgaaggcatt acaaagccgg aaatccagaa ggaattcggc
    11401 ggatgcaacg tttacacaaa gaaagactgc aaagactgct tcgcacgttt ctactgtagt
    11461 ggcggatgtg cggcaaatgc attccatttc cagggagata tcaaaggcaa ttatgaaatc
    11521 ggatgcgaac tccagagaaa acgtgtggag tgcgccatca tgataaaagc cgcactggca
    11581 tgtgattagt gggcagtaat ctgtctgact gataccgccg tcggctgtta tcataacaga
    11641 aaatggctgg caggcggatg aacatgaccg cggacaaaaa atcaagaagg gaaaagaact
    11701 atgaagaaaa gtaaaggaat cgtagtgctg cttctgacac tgatcctgac tgtgttcttt
    11761 tgctttactg cagccgtagg tatcggtcct accggaaccg gtgcagcaaa acatatcaac
    11821 acgggtcttg atcttgccgg tggtgtcagc attacctacc aggctaagga aagcaatccg
    11881 acaagcgaag agatgtcaga tacgatctac aagcttcaga agcgtgtaga gcagtacagt
    11941 actgaggctc aggtatacca ggaaggatca gaccgtatta cagttgaaat tcctggtgtt
    12001 acagatgcag atactattct gaatgatctg ggtaaaccag gttccctgta tttcatcaca
    12061 aaagaagatg ctgacggaaa ccagaacttt actacaggac aggatggata tgttctctcc
    12121 agaactatgg atgagatcaa ggaatccgga agtgttgttc tggaaggttc tgatgtagca
    12181 gatgcccagg gtggtgcgat tcagaatcag aacacaagtg caaaggaata tgtggtaagt
    12241 cttactctta cttctgatgg agaaaacagt ggtaaaacaa aatttgcaga agctacaaag
    12301 aataatgtag gcaagcagat cgctatcgtc tatgacaata acattatcag tgctccgaat
    12361 gtaaatgaag agatttccgg tggaaaagca cagatcagcg gaatgtctga cctggaagaa
    12421 gcacagaacc ttgcttctta tatccgtatc ggttctctgg gactggaact ggaagaactt
    12481 cgttccagtg ttgtagctgc acagcttggt gaagaagcaa tctctacaag tgttcttgca
    12541 ggtgcaatcg gtctgatcat cgttattatc tttatgatca ttgcataccg catacctggt
    12601 atagttgcag gtattgcact gattctttat acatcattaa tgctgattac gctgaatgcc
    12661 tttgatatta ctcttactct tccgggtatt gcgggtatta tccttggtat cggtatggcg
    12721 gtggatgcca atgttattat ttatgcccga atcagagagg aaattggtgc aggagtctca
    12781 gtaaggaatt ctattaagtc cggtttcagc aaagctttct ctgcaatctt tgatggaaat
    12841 attacaacgc tgatcgcagc ctttgtgctg atgtggcttg gttcaggtac tgttaaggga
    12901 tttgcttata cacttgccct tggtatcgtg atctccatgt ttacagcact ggttgtatcc
    12961 agactgattg taaatgcact ttatgcagtt ggtgtacgtg atccgaaatt ctacggatct
    13021 gcaaaagaac gtaaggcagt tgatttcctt ggaaagaaga aagtattttt ggctatttcc
    13081 attatcctga tcctctgcgg tccggcagcg atgtttgcta attcgcatgc aggaaacaaa
    13141 gcgttaaatt acagccttga gttctcaggc ggtacttcta caactgttac atttaatgaa
    13201 gatatggata ttaagaccat tgattctgaa gtaactcctg ttgtagaaga ggtgacagga
    13261 gataagaatg ttcagcctac aaaggtagtc ggaacaaatc aggttgtgat caagacacgt
    13321 tctctgaatc agagcgaacg tgaagctctg cagagtgcac tggttgagaa atttggtgta
    13381 gatgacagca cgatttccac agaaagtatt tcttctacag taagtagtga aatgcgtcgt
    13441 gatgcgatcg tagccgttat agtagctaca atctgtatgc ttctttatat ctggttcaga
    13501 tttaaagaca tccgttttgc aagcagtgcg gtattggcgc ttctgcatga tgttctggtt
    13561 gtacttgcat tctatgctat tgccagagta tctgtcggta atacatttat tgcctgcatg
    13621 cttacgatcg taggttattc tatcaatgct acaatcgtta tttttgaccg tatacgtgag
    13681 aaccttcaca gtggttccag agaaaaactg gcagaaattg taaacacaag tatcactcag
    13741 actcttacaa gaagtattta tacctctttt acaacttttg ttatggtagc tgttctttat
    13801 atcatgggtg tttcttctat ccgtgaattt gcagcacctc tgatggttgg tgttcttgtc
    13861 ggtgcatatt cttctgtatg tattacaggt gcgttgtggt atgtgatgaa aaagaaattt
    13921 gcaggaaaag gacagccggc aattgctgct gcttccgcat ctgcaaagtc ctcttcaaag
    13981 ccgaagaaag cacgtgatgt atcacagaaa gatccgactc agccaaagaa gaaaaacaga
    14041 aaaagagtag ctgaacgtct ggctgccgaa gaagcagcta aaaaacagca gaatgatgat
    14101 gctgaataaa acaataattg tctgaaaaac aggcagacag aaatatcccg gggtaaaact
    14161 ccgggatatt tttatgagga gagaaaatat atggagaaat gggtaatagc agcaaaaaga
    14221 gcagatttta accagatcgg tcaacagttt catattgatc cggtgattgc gagactgatc
    14281 aggaatagag atgtgatcgg agaagataag ataagagagt atctgtcagg aacagtacaa
    14341 gagcttcctt ctccctggct gatgaaggat atggaaaaag ctgtagatat cctggagaaa
    14401 aaaatatcgc agaaagcaaa agtccgtatt attggtgatt atgatattga tggtgtgacc
    14461 tctacataca ttttaatgaa aggccttgcg aggatcggag cagatgtgga tacttatatt
    14521 ccggacagag ttgcagacgg atatgggatt catgcacatc ttatagaaag agcggaaacg
    14581 gaccggatcg atacgatcgt gacctgtgat aatggaattg ctgcggctgc tgaaatccag
    14641 atggcaaagg ataagggaat gacagtgatt attacagatc atcatgaggt tccttacagg
    14701 gaggaaaagg gagaacgcca gatggtgctt ccgccggcag atgcgatttt gaatccgaaa
    14761 caatatgatt gtccataccc gaataaaaac ctgtgtgggg cagtggtggc ctttaaatat
    14821 attacagcac tttacgagag atttggtgtt ccggcagagg agctggaaga ttattatgaa
    14881 ctggcggcta ttgcaacagt aggagatgtt atggatcttc agggagagaa caggattctg
    14941 gtaaaagaag ggctgtgccg tctgaaaaat accaaaaatc aaggattgca ggaactgatc
    15001 cgcgcaaatt ctctggaaga tgctaaaatc acagcttatc atatcggatt tgtgctggga
    15061 ccatgtatca atgccagtgg cagactggat acagctgccc gttctcttgc acttctcaat
    15121 gcaaaaacaa aggaagaagc agcaaggctt gccggagatc ttacagctct taatcagagc
    15181 cgaaaagctc tcactgagaa aggaaaagaa gaggcaatcc ggatcataga gactacagag
    15241 ctgaaaaatg acagagtact ggtagtttat cttccggatt gtcatgaaag tcttgccggt
    15301 attatagcag gcaggatcag ggaaaaatat cacaggcctg cctttgtatt gacgggcggt
    15361 gagacaagtg caaaaggaag cggaagatca atagaaagtt actctatgta tgaagaactg
    15421 gtaaaatgtg cagacctgat gatacagttt ggaggtcatc cgatggcagc aggtctttct
    15481 atagaagaaa aaaatataga agaattccgg agacgtctca atgtcaactg tacgttgacg
    15541 gacgaagaat tgcgtcctaa gatcgtgatt gatgtgccga tgcctgtgtc ttatattaca
    15601 aaagaactgg tagaacagat ttcgcttctg gaaccctttg gaaaagggaa tacaaaaccg
    15661 gtctttgcac agaaaaatct cagagtgctt gattacagca ttatcgggaa aaataaaaat
    15721 gtagtaaaat taaaacttct cgatccgcag gggatttcaa tggaaggcat ttatttcgga
    15781 gaagcagagg attttgtgaa ctttatcagg gaaaaagaca gtatttctgt tacttattat
    15841 ccggagatca acagattcag gggacgagag agtcttcaga ttattattca gaattactgt
    15901 taatattacc gcttggtttg taaccgccgg taagcctgga aatacaaatg tcagggctta
    15961 acagtaactt gattctgaaa taaaaaggtg atatactata aaatatttat gagcgaacag
    16021 caatataaca cacactggag gagaaataaa atgaagaaaa ttgaagatta tgtattaagt
    16081 ataccggatt ttcctgaacc ggggattatt ttcagagata ttacaagtgt tctgcaggat
    16141 gcggatggcc tgcagttggc aatcgactcc atgcaggact gtcttaagga tatagatgtg
    16201 gacgtgattg caggaacaga gtccagaggc tttatttttg gtgtaccgat cgcatataat
    16261 cttcataaac catttgtacc gattcgtaaa aaaggcaaac ttccccgcga aacagtatct
    16321 gtaagctatg atctggaata tggcagtgca gagattgaaa tgcataaaga ttctataaaa
    16381 ccaggtcaga aagtggttat cgttgatgat ctgatcgcaa caggcggtac gatcgaagca
    16441 gcgatcaagc tggtggaaca gcttggcggt gaggttgtca aggttgtatt tctcatggaa
    16501 cttgcaggtt taaagggacg cgaaagactg aatgggtatg atgtagcgtc cgtaatttgt
    16561 tatgatggta aataagcaca gctgattgtg caggacaggc aggtgggagc atatgacaga
    16621 ggtaacaaaa agtacagaag caaaaaaaga tgaaatgcag gttgaaaaag agaagctgga
    16681 atctgtaaag agagcagatg cggcagtaaa gaccatgcat gattttacaa gtccggaggt
    16741 gctttataaa gaactgataa acagtgttct gaagtatcat ccatcaacag atatttccat
    16801 gatagagaag gcatataagg ttgcaagtga agctcatgaa ggacagaaga gaaagtccgg
    16861 agagccatac atcattcatc ctttgtgtgt tgccatcatt ctggcagatc tggaacttga
    16921 caaagaaacg atagttgcag gtcttcttca tgatgcagtt gaagatacct ggatgaccta
    16981 tgaggaagtg gagaaggaat ttggttcaga ggttgcactt cttgtggatg gtgttaccaa
    17041 gctgggacag ttatcttatt ctgcggataa agtagaagtt caggcagaga acctcagaaa
    17101 gatgtttctt gccatggcta aggatatcag agttattctg atcaagcttg cagaccgtct
    17161 tcataatatg cgtaccttac agtatatgcg tcctgaaaag cagcaggaaa aggccagaga
    17221 gaccatggat atttatgctc ctattgccat gcgtctgggt atttccaaga taaaggtaga
    17281 gctggatgac ctgtcgctga aataccttaa gccggatgta tattatgacc tggtgcataa
    17341 ggttgccctg cgtaaaagcg agagagaaca gtttgtaggt gcgatcgtaa aagaagttaa
    17401 gaaacatatg gatgatgcca atattaaggc gcaggtggac ggacgtgtaa aacacttttt
    17461 cagcatctac aagaagatgg taaatcagga taagactatt gatcagattt atgatttatt
    17521 tgctgtccgt attcttgtag atacagtgaa ggattgttat gctgcccttg gtgtgatcca
    17581 tgagatgtat aagccgattc cgggacggtt taaagattat attgccatgc cgaaacccaa
    17641 tatgtatcag tcattgcata ccacattgat cggacccaac ggacagccct ttgaaatcca
    17701 gatccgtact tatgaaatgc acagaactgc agaatatggt atcgctgcac actggaaata
    17761 taaggagtcg tctgacggaa aggctcctgt aggtaagagt gaggaagaga aactgaactg
    17821 gctgcgtcag attctggaat ggcagagaga catgtctgat aacaaagaat tcatgagtct
    17881 tctgaagaat gacctggatc tttttgcgga cagtgtttac tgtttcactc cacagggaga
    17941 tgttaaaaca cttccaagcg gttctacacc ggtggatttt gcatacagtg ttcacagtgc
    18001 agtcggaaat aagatggtag gtgccagagt taacggtaag ctggttccta ttgaatatga
    18061 gatcaaaaac ggtgaccgta ttgaaattat tacttcccag aattctcagg gaccaagccg
    18121 cgactggctg aaactggtta agagtactca ggcaaagaac aagattaacc agtggttcaa
    18181 gaaggaatta aaagaagata atattcttaa gggtaaggag atgcttgcgc agtatgcgcg
    18241 cgcaaaggga tttaagattg caaattatac aaaaaaccag tatctggaag ctgttttgcg
    18301 taaatatggt ttcagggact gggattcagt acttgctgca attggtcatg gcggattgaa
    18361 agaaggtcag gttttcaata agctggtaga ggcttatgat aaggaaaata agaagaatct
    18421 gacagatgag caggttcttg aggctgcttc tgagacacag gagaagcttc acattgccaa
    18481 gagcaagagc ggcattgtgg taaaaggaat ccatgatgtg gcagtccgtt tttccaagtg
    18541 ctgtaatcca atcccgggtg atgagattgt aggctttgtt acaagaggac gtggaatcac
    18601 gattcatcgt acagattgtg tcaatgtgct gaatatgtct gagacagaca ggacacgact
    18661 gattgaggca gagtggcagc agcctgatac caaggaaaaa gagaagtata tggctgagat
    18721 tcaggtttat gcaaataacc gtacagggct tcttgtggat ctttctaaaa tatttacaga
    18781 acgtaagatc gacctgcgaa gtatcaacag ccgtacaagc aagcaggaga aggcaactat
    18841 ttccatgagt tttgagattg gaagcaaaga ggaactgcgt tccctgatcg agaagatccg
    18901 tcaggtagag agtgtcattg acgtagagag aactacaggc tgatcatgga aaaatctgct
    18961 ggaacattat tttatggaac tgctgcagat tgacagaaag gaataacatg aagaatttag
    19021 aattacagaa atgtatatta ggacctgtat atacaaattg ctatatcctt aagaataaag
    19081 aaaccggaga actgatcatt gttgatcccg cagattgtcc ggagaagatt gaaatgaaga
    19141 tttcccggat gaatggaaaa ccggtggcga ttcttcttac ccatggacat tttgaccaca
    19201 ttctggctgc acaggcagta aaggagaaat ataatattcc gatttatgcc tgtcgtcagg
    19261 aagaggagat gctccgcgaa ccttcgatca atatgactgt acattatgga cagggatgtt
    19321 ctattgtgcc ggatgtattt ctggaggatc tggatgttat cagactggcg ggattttccg
    19381 ttcagatgat ccatacaccg ggacatacca aaggaagctg ctgttattat ctgaaagatg
    19441 aaggtgtatt gttcagcggt gatacagtgt tctatggctc tgttggaaga acggattttc
    19501 cgggtggaag tacagcagaa attgtgagaa gtctccataa actggtagat tcgcttcctg
    19561 aagagaccga ggttttcccc ggacatgatg catctaccac tattggttat gaaaagaggt
    19621 ataatccatt tgtgtaaaat aggcattctg tttaagaaca gagattttga acatgatgtt
    19681 tatgaactga tcaaagcgtt ttatcccgaa gcggagatac atactcttta tgaaaatgct
    19741 gaagcagagt atgacctccg cttcagtgtg gaacgggata atgacagtta tatcataaaa
    19801 tacgaaagga cagagaatct gtcgaaacag gaaacagagc aaaaaggggt aatttccgca
    19861 gacatacttt ctaaagagaa tgcaggctgt ggaatacagg atgctcatgc tctgagaaaa
    19921 gagaataaag ataatatcaa atatgctctg tatcagttgt tggtaaaact gacgggcaga
    19981 actcttccat ggggaaatct gacaggaata cgtcctgcca aactggcaat gggaatgatc
    20041 gaatccggaa tgaaaaatac ggaagcagcc cgggagatgc gtgagagata tctggtgagt
    20101 ccgcagaaaa cagcgcttgc catcactatt gcaaacaggg aaagagagat tctgaaggat
    20161 attgactatg aaaatggata cagcctttat attggaatcc cgttttgccc aagtatctgt
    20221 ctgtattgtt ccttcagctc ctatccactg aaagtgtggg agaagagaac agatgaatat
    20281 gtggaagctc tctgccgtga ggtaagagag actgctctta tgatgaaggg aagaaaactg
    20341 gacaccatct atattggcgg cggtaccccg actacactgc ttccacatca gatccgtaag
    20401 ctcctggata cagtgggaga agcttttggc tatgaaggac tggcagagtt tactgtggaa
    20461 gccggcagac cggacagtat cacacgtgaa aagctgatgg cgatcaggga gtatccggta
    20521 acaagaattt ccgtaaatcc acagactatg aatcaggaaa ccctggatat tatcggccgc
    20581 agacatactg tggagcagac aaaagaagcg tttcatctgg cacgagagct gggatacgat
    20641 aacattaaca tggatctgat cgtaggtctt ccgggtgagg atattcacat ggtagagcgg
    20701 actcttgaac aggttcgtga actggcaccg gacagtatta ccgtacattc actggcagtg
    20761 aaacgtgcag caaggctgaa tatttttaaa gagaaatatc aggaaatgtc ttttgagaat
    20821 aatcaggaga ttatggatct gaccatgaaa actgcgtatg aaatgggaat gagtccttat
    20881 tatctgtaca gacagaagaa tatgaaggga aattttgaaa atgttggcta tgcaaaggtt
    20941 gacaaagcgg gaatttacaa tatactgatt atggaggaaa aacagcctat catcgcactg
    21001 ggagcaggcg gttcttccaa gctggtcttt gaccatggac agagaattga acgtgtggag
    21061 aatgtaaaag acgtttctaa ttatatttcc cgcattgatg agatgatcga gagaaaacgg
    21121 acagcaatag ctacctggct gtaggatgtg gaggtaacat tttggacaca gtacaaaaga
    21181 cagcggcagg ttcacagcag aggatcctgg aatttgacct tgcttctgaa ctgcatcatg
    21241 gaatgctggt aagtaatctg gcttatgcgg ttgcagagga gatgggactg ccgcatgaac
    21301 agtgctatga gcttgcaata gcaggaatgc tccatgatat aggaaagctg aagctgacaa
    21361 gttatattaa cggacaggag caggatcctc tggtgattga ggaactgaag tatgtccgga
    21421 tgcattctgc attgggatat gaggaactta aagggcaggg atattcggat tttgtattgg
    21481 agagtatcct gtaccatcat gagaattatg atggcagtgg atatccgtcc aataaagcag
    21541 gtgatgacat acccataggt gcccggatac tcagagtctg cgatgtata
//
