LOCUS       c00019_gnlPro..        15751 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MDLLEMBK_19.
ACCESSION   c00019_gnlPro..
VERSION     c00019_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 18:48:20
            Original ID  :: gnl|Prokka|MDLLEMBK_19
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15751
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15751
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2795:5751]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2796..5751
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..15751
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15751
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             2..2011
                     /locus_tag="ctg19_1"
                     /transl_table=11
                     /translation="HRILLISYTNKAAAELTERMATNGLKGYTFHKLAIDIIGRATGTK
                     PSICDNTDSLFVDIYHTLLGNKDFKNSIVEYFIDYQSNEADWEQRKNERREKLSEQKNV
                     QLKAMCPDMDGRAIYVRSEQEQKICFVLSSLGVRFRYEEAYEHQLADEMHSQYRPDFSI
                     YFEQNGVTKRIYLEHFGVDEHGLVPAWFAKDKNITYEEANQKYNDGITWKKAAHEKFGT
                     QLLVTSSADFHYSDIRDKLRKLLDDAGVPIQEKTDEELYDLVLPKGSKQEKAFIRLVVT
                     FVTLVKSSCKSVKDVLKRAKYAEDERSVFIIKNIFQPVYERYISALRDNNQIDFTDAIL
                     QATEICRVSRPVEYDYIIVDEFQDISVDRYNFLKVLREGNPPAKLYCVGDDWQSIYRFS
                     GSDMALFNQFSEYFGATEINKIETTYRFGEPLVSLSSHFIQRNKSQIQKDIHSFSSEMK
                     TELEFYSYDRRDYCNTIGQLVASIPSDKSIFLLGRYSFDDYYLSFMYQSIKEGNRFFYV
                     IGGRKIEFLTVHKSKGLEADYVILLQCNKDTYGFPSLVSDDPVLNYVLTKSDQFPYGEE
                     RRLFYVAITRAKMKTLVLYDKRFPSVFVDEFLHPEKVSEESYVKHPNANKRWTRSADQF
                     LLKLHNEGKSVKYIANKMGRSQTSIVMRLNKLNQ"
     CDS             2796..5024
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg19_2"
                     /sec_met_domain="Gly_radical (E-value: 2.3e-46, bitscore:
                     148.2, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1171.1, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKTFTNGLWNKEINVSDFVSKNIAPYTGDASFLQGPTERTKR
                     IWDICLKALEEERNNNGVRSLDNTTVSTITSHKAGYIDKDNELIVGLQTDELLKRSIKP
                     FGGINVVAKACRENGVEVDDKVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRLALYGIDRLIEAKQEDLRNLTGPMTEARIRLREEVAEQIKALKDIK
                     VMGEYYGLDLSHPATSAQEAVQWVYMAYLAAIKEQDGAAMSLGNVSSFLDIFIEYDLAH
                     GKINETFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTEAIGGRFNDGRVKVTKT
                     SFRFLQTLYNLGPSPEPNLTVLWSPELPEGFKDFCAKVSVDTSSIQYENDNLMREVRNC
                     DDYGIACCVSYQAIGKQIQFFGARANLAKALLLAINGGRCENTGTVMVKGIPVLTGETL
                     KFEEVMANYKKVLTEIARVYNEAMNIIHYMHDKYYYEKAQMAFIDTNPRINLAYGVAGL
                     SIAIDSLSAIKYAKVTARRNEIGLTEGFDTEGSFPCFGNNDDRVDHLGVDLVYYFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGVAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGPTPEERVENLVTMMDGYFTKGAHHLNVNVLN
                     REMLEDAMEHPEKYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             5026..5751
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 75.5;
                     E-value: 1.7e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg19_3"
                     /sec_met_domain="Radical_SAM (E-value: 7.5e-31, bitscore:
                     99.2, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINVHSYESMGTFDGPGLRLVVFLQGCPFRCLYCANPDTIDVKGG
                     TPTTPEEILQMAISQKAFFGKKGGITFSGGEPTLQAEALIPLFKELKANGIHICLDSNG
                     GIWNEKVEELFSLTDLVLLDIKQFNPERHRTLTGRSNEQTLRTAAWLEEHEHPFWLRYV
                     LVPGYSDSEEDIRLLGESLGKYRQIQRVEILPYHRLGVHKYEVMGWDYKLKEVKENTPE
                     QLERAEKLFKEYFTNVITN"
     CDS             5793..6785
                     /locus_tag="ctg19_4"
                     /transl_table=11
                     /translation="LLFIYRTRILFFQVIGNLLYIITTATHHKDEITRFYHIIHLIVIE
                     SQCIVSYLKSYSFAFTRIQMNFPEALQLLYRARNRRYLILHIQLDYFLSCTLTGISHFY
                     RHLRMDACILARQQFQIRISKIRIRKPISERIGRLSGSIDIGCLISLLQCGRTTGTLIL
                     VINGNLPYVCRKCHGQFSRRIILSPQHIAYGIAGLTPQPPSTQYRISMFPYLIEDYRTP
                     THDKSNDRFSSLCQFRHQLLLPLGYGYIHFGSLLATLTESLAYRHNNDIRSLSSLQCFL
                     QSGQLIALHIIAFSIVHLQSFPDQCIIQGHHFAPVRSGGPSACHIVLGF"
     CDS             complement(6824..7009)
                     /locus_tag="ctg19_5"
                     /transl_table=11
                     /translation="MMQYGVYWRRNMSWDCLRTLFATVIRKERPEYSMRPKSVMLRSVW
                     PSVPLYCWRIGNLCFR"
     CDS             7410..7721
                     /locus_tag="ctg19_6"
                     /transl_table=11
                     /translation="MFHTCHDSRRVCQIVSLQASDTRLRYPRTIIRVLTGPFHDASPTC
                     VPRNIHHRGKNPVQTIGGTFQSIVACSFLNHGQIETCSLGKRKRKSGTIAVDNIQSEN"
     CDS             7876..8043
                     /locus_tag="ctg19_7"
                     /transl_table=11
                     /translation="VHCASWPIFSSSVICFIKLEMNFSFSVVCAEVKVLPSPHRQTISI
                     IIFFILPFLF"
     CDS             complement(8055..10049)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fn3-like"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_3_C"
                     /gene_functions="other (smcogs) SMCOG1041:Fibronectin type
                     III-like domain (Score: 80.5; E-value: 2.6e-25)"
                     /gene_kind="other"
                     /locus_tag="ctg19_8"
                     /sec_met_domain="Fn3-like (E-value: 1.7e-25, bitscore:
                     80.5, seeds: 729, tool: rule-based-clusters)"
                     /sec_met_domain="Glyco_hydro_3 (E-value: 1.6e-31, bitscore:
                     101.2, seeds: 11, tool: rule-based-clusters)"
                     /sec_met_domain="Glyco_hydro_3_C (E-value: 8.8e-51,
                     bitscore: 164.1, seeds: 116, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LGVQEEGVMATVKHFAANNQEWSRHHASSDVDERTLQEIYFPAFR
                     KAVQEAGVGAVMDSYNPLNGVHATENSWLNIDVLRKQWGFKGILMSDWTSVYSGVGAAN
                     GGLDLEMPVGKFMTREILIPAIENGIVKEETIDAKVRHILQTLIAFGALDTPREDKSID
                     KDNAQSKEIALDLAREGVVLLKNDNGTLPYRNGRTLVIGPNADIIPTGGGSGFVTPYSV
                     VSLYDGMVQLKGGRQIELLSDSLLYKDMSQQIYTDDSFTQNGFKSEYYNTRNLTGELFQ
                     AAIEPAIDYAWKYGAPFDGMPVDQFSARWTGVYKADKDGTVKFQLAGDDGYRLFVNDKL
                     ITGDWGNHSFSTRSAFMQVSAGEIYRLRIEYFDNVGEATVSFQAGMMDEERLASSLKHA
                     RNVIVCAGFNSSTEGEGFDRPFALSYGQEYLINKVASLHDNVAVVVNAGGGIDFRNWGQ
                     SVQAILMAWYPGQEGGKALAEIITGKLSPSGKLPVSIEEKWEDNPVYGNYYDNRNVPHK
                     RVQYAEGVFVGYRGYDRNGKQPLYPFGYGLSYSSFEYSNLSVEKTGGSRVTVSFDIKNT
                     GKMDAAEAAQVYVRDVECSVPRPLKELKGYDKVYLKKGETKRVRILLDEEAFAYYDVES
                     HRFVVEKGTFEILAGPSSADLPLKATVVL"
     CDS             complement(10694..11194)
                     /locus_tag="ctg19_9"
                     /transl_table=11
                     /translation="MPYLQRREKKIADIDHKQPLSFGVSVRKNLAKGFSVESGLTYTYL
                     ASDVRYEGSSEKISQKLHYIGIPVRANWNFVDAKNFTMYVSAGGVIEKCVYGKIGTESE
                     TVKPVQLSVMGAVGAQYNISNRVGLYVEPGVSYFFDDGSSIQTIRKENPCNFTLQAGIR
                     LTY"
     CDS             11688..11963
                     /locus_tag="ctg19_10"
                     /transl_table=11
                     /translation="MELVRMAGTVCSGKTSGATAKAGTDVCRISFPTGLCNSHRLTDET
                     ATSNTAAAATAQRRKGIILCGPVIGAPETDNSFSNRSHPATGSGSE"
     CDS             complement(12023..12571)
                     /locus_tag="ctg19_11"
                     /transl_table=11
                     /translation="MEEQELAERCRQGDNLARKELYERYAGRMLSVCLRYAGDRETAQD
                     LMHDGFLKLFDSFDKFTWRGEGSLRAWMERVMVNTVLQYLRKNDVMNQSSALENAPEAY
                     EEPEGSSIDVIPQKVLMQFISELPAGYRTVFNLYIFEEKSHKEIARLLGINEKSSASQL
                     TRAKATLAAKVREWMKRND"
     CDS             12753..13457
                     /locus_tag="ctg19_12"
                     /transl_table=11
                     /translation="MKKLRMTLAASMLLFLTAIVLQSCLDDWDDKYDTLFAVGTVKVIE
                     GKDYYFSLDEGSKLYPSDTTYVHDYAVIDGQRAFIYFRELEEKLPGYEYNAQIKHIENI
                     LTKDIYSMPAEKADSIGDDNINATDLWITGEYLNIKYQFYHSNNEDKKHMQNLVINEAS
                     TGENDKPDYVNLEFRHNAYNDSQLTLGTGLASFKLDNIAEQLKEKKGLNIRVKSLYDGE
                     RFMTIDIKKENN"
ORIGIN
        1 tcatagaatc ttactcatta gttacacgaa caaagcagca gccgaactta cggaaagaat
       61 ggctactaac ggcttgaaag gttatacttt tcataaatta gccattgata ttattggaag
      121 agcaacaggc acaaaaccat ctatttgcga taatactgat tctttattcg tagatattta
      181 tcacacttta ttagggaata aggattttaa gaatagtata gtagaatatt ttattgatta
      241 tcaatccaat gaagcggatt gggagcaacg caagaatgaa aggcgagaaa agttatcgga
      301 acaaaaaaat gttcagttaa aagcaatgtg tcccgatatg gatggtcgag ccatatatgt
      361 gagaagtgag caagagcaaa agatatgctt tgtcttgtct tcacttggag taagattcag
      421 atatgaagag gcatacgaac atcaattggc agatgaaatg cactctcaat atcgccccga
      481 tttttccata tatttcgagc aaaatggagt aaccaaacga atctatctgg agcatttcgg
      541 ggttgatgaa catggtcttg ttccagcttg gtttgcaaag gataaaaata taacatacga
      601 agaagccaat caaaaatata atgatggtat aacttggaag aaagcagctc atgagaaatt
      661 tggcactcaa cttttagtaa catcaagtgc tgatttccat tattctgata ttagggataa
      721 actccgtaaa ctattagatg atgcaggtgt accaattcaa gagaaaacgg atgaagagtt
      781 atatgattta gttttaccca aaggaagtaa gcaggaaaag gcatttatac gacttgttgt
      841 tacttttgtg acattagtga aatcaagctg taaatcagtt aaggacgttc ttaaacgagc
      901 gaagtatgca gaggatgaac ggagtgtttt tattatcaag aatatattcc agcctgtata
      961 tgaacgctat ataagcgcat taagagataa taaccaaatt gattttactg atgcgattct
     1021 tcaagccaca gaaatatgtc gtgtttcacg tcctgttgag tatgattata tcatcgtgga
     1081 cgagtttcaa gacatatctg ttgaccgtta taacttttta aaagtgttgc gtgagggaaa
     1141 tccaccagca aagttgtatt gcgtaggcga tgactggcag tccatatatc gtttttcggg
     1201 aagtgatatg gctcttttca atcaattctc cgaatacttt ggagcaacag aaataaataa
     1261 gattgaaacc acatacagat ttggagaacc tttggtttcg ttgtcctctc atttcataca
     1321 acgcaataaa tcacaaattc agaaagatat acactcgttc agttctgaaa tgaaaacaga
     1381 attggagttt tattcttatg acagacgtga ttattgcaat acgatagggc aacttgtagc
     1441 ttctattcca tcagacaaat caatattttt gttgggacgt tattcctttg atgattatta
     1501 tctctctttt atgtaccaat ccatcaaaga gggcaatagg ttcttttatg tgataggagg
     1561 acgaaaaatc gagtttttga ctgtacataa atcgaaaggt cttgaagcag attacgtaat
     1621 actcttgcaa tgcaataaag acacttatgg cttcccatct cttgtgagtg acgaccctgt
     1681 gcttaactat gtactaacta aaagcgacca attcccatat ggagaagaac gtagattgtt
     1741 ttatgtagca ataacaaggg caaagatgaa aactcttgtg ctatatgaca agcgtttccc
     1801 ctctgtattt gtggatgaat ttttgcatcc tgaaaaggtt tcagaagaga gttatgtgaa
     1861 gcaccccaat gccaataaaa gatggacaag aagtgcagac caatttctat tgaaactgca
     1921 taatgagggt aagagcgtca aatatattgc aaacaaaatg ggcagaagtc aaacgtcaat
     1981 tgttatgcga ttgaataaac ttaatcaata ataatgctct atttttaccc aataacattg
     2041 gttgtgtccc tattttcaag tataaatctt aaataataca aaagcaccca attttacact
     2101 cttgggtgta aaattgggtg cttgttttac aatctgctga ttttcagcgt ttattgcgga
     2161 gagacaggga ttcgaacccc gggtgcctcg cagcacaacg gttttcaaga ccgccgcaat
     2221 cgaccactct gccacctctc caaaacttct ttttcagaag tgcttttctt ttaaagcggt
     2281 gcaaagatac aaatcatttt ttattctaca aacttttctg cacaaaaaca gagcaattat
     2341 accaaaattc ttgtttatac ccactacgga acgaacataa cggcatttag gctatttgtt
     2401 gaaatttatc aagggcaaga cagagtttta taacttactg gctatcagta tatttacaaa
     2461 gaaccacatt cagtatacga ttgaacccta ttcagtatac gactgaatgg cattcactat
     2521 acgactgaat taggttcaga atacgactgt tccttaaacc tacatcattt gtaaataatg
     2581 cagattatta ttcggttctt gtttcaattc ataaaccaca tataaagaaa gtattaacat
     2641 ctctactccc ccggacattc actacctaat aatagttatt ttatgctgtt caacataaaa
     2701 agagaagtat ctcttataaa attacggaat ttattcagta tttttgtgcg ctctaaagga
     2761 taacattatc taacctacta acaaaaacaa attttatgga attgaacaaa acctttacca
     2821 atgggctttg gaataaagaa atcaatgtca gtgatttcgt cagtaaaaac atcgcaccct
     2881 ataccgggga tgcatctttc ttgcagggac ctaccgaacg taccaaacgt atctgggaca
     2941 tctgtctgaa ggctctcgaa gaagaaagga acaacaatgg cgtccgttca ctggacaata
     3001 ccaccgtatc taccatcact tctcataaag ccgggtatat tgataaggac aatgaactta
     3061 ttgtcggttt gcagactgat gaactgttga aacgatccat caaacctttc ggaggcatca
     3121 acgtggtagc aaaagcatgc cgtgaaaacg gagtggaagt ggacgataaa gtaaaagaca
     3181 tcttcaccca ttaccgcaaa acacataacg acggcgtatt cgatgtatat accgaagaaa
     3241 tccgttcctt ccgctcactg ggattcctta ccggattgcc cgacaactat gcccgcggac
     3301 gtatcatcgg cgactaccgc cgattggctc tctacggcat cgaccgtctg attgaagcca
     3361 agcaggagga cttgcgcaac ctcaccggcc cgatgaccga agcacgcatc cgtctacgcg
     3421 aagaagtggc ggaacaaatc aaagctttga aggacatcaa ggttatgggc gaatattacg
     3481 gactcgacct cagccatccg gctacatcag ctcaagaggc cgtgcaatgg gtatacatgg
     3541 catatcttgc tgccatcaaa gagcaagacg gtgctgccat gtcattgggt aacgtatctt
     3601 cgttcctcga tatattcatt gaatacgatc tggctcacgg aaaaatcaat gagacgtttg
     3661 cgcaagaact gatagaccag ttcgtcatca agctgcgcat ggtacgccat ctgcgtatgc
     3721 agtcgtacaa tgatatcttt gccggtgacc cgacttgggt gaccgaagcc atcggaggac
     3781 gcttcaatga cggacgcgtg aaagtcacca agacttcttt ccgcttcttg cagacgctat
     3841 acaacctcgg tccttctccg gaaccaaact tgaccgtact gtggagtccc gaactgccgg
     3901 aaggcttcaa ggatttctgc gccaaagttt ccgtagatac cagctccatc cagtacgaaa
     3961 acgacaacct gatgcgcgaa gtgcgcaact gcgacgatta cggcattgcc tgctgtgtat
     4021 cctaccaagc catcggcaag caaatccagt tcttcggcgc acgtgccaac cttgccaagg
     4081 ccctgctgct tgccatcaac ggtggccgtt gcgaaaacac cggaactgtc atggtgaaag
     4141 gtattcccgt attgaccggc gagacactga agtttgagga agttatggcc aactacaaga
     4201 aggtactgac tgaaatagcc cgtgtctaca acgaggccat gaatatcatc cactacatgc
     4261 atgataagta ttattatgag aaggcccaga tggcattcat cgataccaac ccacgcatca
     4321 atctggcata cggtgttgcc ggcctttcca tcgccataga ctcactgtcc gccatcaaat
     4381 atgccaaagt cactgcacgc cgcaacgaaa tcggcctgac cgaaggtttc gacactgaag
     4441 gctcattccc ctgcttcggc aataatgacg accgtgtgga ccacctggga gtagacctcg
     4501 tttactattt cagcgaagaa ctgaaaaagc tgcctgtcta caagaatgcc cgtcccaccc
     4561 tttccttgct gactatcacc tccaacgtga tgtacggcaa gaagaccggt gccactccgg
     4621 acggacgcgc caaaggtgtt gcctttgctc cgggtgccaa cccaatgcac ggacgtgaca
     4681 agaacggtgc catcgcttcc ttgagctccg tagccaaatt gcgctaccgc gactcgcagg
     4741 acggcatcag caatacgttc tccattgttc ctaaatcact gggcccgaca ccggaagaac
     4801 gtgtagagaa cctggtaacc atgatggacg gctacttcac caaaggtgcc caccatttga
     4861 acgtaaacgt actgaaccgc gaaatgctgg aagatgccat ggaacatcct gaaaagtatc
     4921 cgcaactcac catccgcgtt tccggctatg ccgtgaactt cgtgaagttg agccgcgagc
     4981 atcagttgga agtcatcagc cgttcattcc acgaaagaat gtaatatgat aaatgtacac
     5041 tcctacgaaa gtatgggaac attcgacggg ccgggtctcc ggctcgtcgt tttcctgcaa
     5101 ggatgtccgt tccgttgtct gtattgtgcc aatccggata cgattgatgt aaaaggaggc
     5161 actcccacca ctccggaaga gattctgcaa atggctatca gccaaaaggc attcttcggg
     5221 aagaaaggag gtattacttt ctccggcggt gagcctaccc tgcaagcaga agcgctgatt
     5281 cctcttttca aggagctgaa ggcgaacggc atccatatct gtctggacag taacggaggc
     5341 atctggaatg aaaaggtgga agagctcttt agcctgactg acctcgtgct gctggacatc
     5401 aagcaattca atcccgaacg ccaccgtacg ctgacgggac gaagcaacga acagacactc
     5461 cgcaccgctg cctggctcga agaacatgaa caccccttct ggctgcgtta tgtactggtt
     5521 cccggttaca gcgattcgga agaagacatc cgcctgctgg gtgaaagtct cggcaaatac
     5581 cggcagatac aacgggtgga aatacttcct taccaccgtc tgggcgttca caaatacgaa
     5641 gtcatgggat gggattacaa attgaaagaa gtgaaggaaa atactccgga acaactggaa
     5701 cgggcagaaa aactgttcaa agagtatttc acgaatgtga taaccaacta aaacagaaaa
     5761 gcaaggctgt ccggatatga ttccagacag ccttgctttt catttatagg acaagaatcc
     5821 tattctttca agttataggt aatctgctgt acatcatcac tactgccacc caccataaag
     5881 acgaaatcac caggttctac catataattc atctcattgt catagaatcc cagtgcatcg
     5941 tcagttatct gaaaagctac agttttgctt tcacccgcat tcagatgaat tttcctgaag
     6001 cccttcaact cctttatcgg gcgcgtaaca gacgctacct tatcctgcac atacaactgg
     6061 actacttcct ctcctgcaca cttaccggta ttagtcactt ttaccgacac ctccgtatgg
     6121 acgcctgcat ccttgcccgg cagcagtttc aaatcagaat atccaaaatc cgtatacgaa
     6181 agcccatatc cgaaaggata ggcaggctca gtggaagcat cgatatagga tgccttataa
     6241 gtctgttgca atgcggtagg acgaccggta ctcttattct ggtaataaat gggaatctgc
     6301 cctacgtgtg caggaaatgt catgggcaat ttagccgaag gattatactc tccccacaac
     6361 acattgcata tggcattgcc ggcctcactc cccagccacc aagtacacag taccgcatca
     6421 gcatgttccc ttatctcatt gaagattacc ggacgcccac acatgacaag agcaatgaca
     6481 ggttttccag tctttgccag ttccgacacc agcttctgct gcccctcggg tatggctata
     6541 ttcactttgg aagccttctc gccactctga ccgaatctct cgcctaccgc cacaacaatg
     6601 acatccgaag cctcagcagc ctgcaatgct tcctgcagtc cggtcaattg attgctcttc
     6661 atatcatagc cttcagcata gttcacctcc agtcctttcc ggaccagtgc atcatacaag
     6721 gtcaccactt tgctccggtc cgtagtggcg gcccaagcgc ctgccatatc gtattgggat
     6781 tttgagagtc ctcctatcaa ggctatcttc ctcgtctgtg ccgtcaacgg aagcacagat
     6841 tccctattct ccagcaatac aacggaacgc tcggccatac ggagcgaagc attacggact
     6901 tcgggcgcat tgagtattct ggccgctctt tccggattac agtagcgaaa agggtcctca
     6961 aacaatccca actcatattt cttctccaat atacgccgta ctgcatcatc aagcacactc
     7021 tcctttactt tcccttcttg aacaagctcc ttcagataag tcaagtagca ggtacttacc
     7081 atctccatgt ccagaccagc attcagcgct ttggctgcgg catctttctt gtcaacagca
     7141 taacggtggt tcaccaattc ctctaccgaa ttataatcgg acacaacaaa tcccttaaat
     7201 ccccactgct ctctcaatag ccggttgagc aagaaatcat tggcagtaca aggaatatta
     7261 ttaaaatcat tgaaagcact catcacggta gctgctccta cctttatggc cgccttatag
     7321 ggaggcatat aaaaattggc aaagtggccc attgacatat ccacactatt atactccttt
     7381 cctgctatcg gtgcaccata tccggcaaaa tgtttcatac atgccatgac agtcgtcgtg
     7441 tctgccaaat cgtctccttg caagcctctg acacgcgcct ccgctacccg agaaccataa
     7501 taagggtcct caccggcccc ttccatgacg cgtccccaac gtgcgtccca cgaaatatcc
     7561 accatcgggg caaaaaccca gttcaaacca tcggcggcac tttccaaagc attgtagcgt
     7621 gcagcttcct caatcatggc caaatcgaaa cttgcagcct cggcaagcgg aagcggaaat
     7681 ccggtacgat agccgtggat aacatccagt ccgaaaatta aaggaatgcg caaacgcgat
     7741 tgcaaagcaa gctcttgata acggcgtata tcctttactc ctatcacatt cagcatagag
     7801 cctattctgc cttgccggac atactcttct ttaggaatat ttccaccgtc gggtccggta
     7861 aaattccctc ggtaggtgca ttgtgcaagc tggcctatct tttcatccag cgtcatctgc
     7921 ttcatcaagc ttgagatgaa tttctccttc tccgtagttt gtgccgaggt aaaggtgtta
     7981 ccaagtcccc acagacaaac catcagtatt attatctttt tcatactgcc attcttgttt
     8041 tgatatttat tttatcataa aacaacagtt gccttcaatg gtaaatcagc tgaagaagga
     8101 cctgccagaa tctcaaaagt ccccttttcc actacaaacc gatgtgattc cacatcatag
     8161 taggcaaagg cttcctcatc cagcaatatc cgaacgcgct tggtttcacc cttcttcaag
     8221 taaaccttat cgtagccttt caactccttc aatggacgcg gaacagaaca ttccacatcc
     8281 cgcacatata cctgagccgc ttccgcagca tccatctttc cggtattctt gatgtcaaag
     8341 cttaccgtaa cccggcttcc ccccgtcttc tcaacactca gattactata ttcaaaacta
     8401 ctgtatgaca gtccataccc gaaaggataa agcggctgct ttccgttccg gtcatatccc
     8461 ctataaccta cgaaaacacc ttcggcatac tgcacccgtt tatgaggtac attgcgattg
     8521 tcataataat taccatatac cggattatct tcccattttt cctcgatgct gactggtagt
     8581 ttgccacttg gcgaaagctt gcccgtaatg atttcggcaa gggcctttcc accctcctgc
     8641 cccggatacc atgccatcaa aatagcttgt acactctgcc cccaattgcg gaaatctatt
     8701 ccacctccgg cattcaccac cacagccaca ttatcatgaa gtgaagccac tttattaatg
     8761 agatattcct gcccgtatga caatgcaaac ggacggtcga acccttcacc ttctgtactg
     8821 ctgttgaacc cggcacatac aataacattc ctggcatgct tcagtgaaga ggccaaacgc
     8881 tcctcatcca tcattcctgc ctggaaactg acagtcgcct cacccacatt atcaaaatat
     8941 tcaatacgca accggtatat ctcccctgca ctgacctgca taaatgcact gcgggtactg
     9001 aatgaatggt tcccccaatc tccggtaatc agcttatcgt ttacaaacag acggtatccg
     9061 tcatcgccag ccagctggaa cttgacagtt ccatccttgt cagccttgta aactcccgtc
     9121 caacgggcag aaaactgatc taccggcatg ccgtcgaacg gtgcaccgta tttccaggca
     9181 tagtctatgg caggctctat agcagcttga aagagttctc cggtaagatt acgagtatta
     9241 taatattcgc tcttaaaacc gttttgcgta aaactgtcat ccgtataaat ctgttgggac
     9301 atatccttat aaagaaggct gtcagacagc agttctatct gtctgccgcc cttcaactga
     9361 accataccgt catagagcga cactaccgaa taaggagtga caaatccgct tcctcctcct
     9421 gtgggaataa tatcggcatt aggcccgatt accaatgttc taccgttccg gtaaggcaac
     9481 gtaccgttgt catttttcaa taacactact ccttccctcg ccaagtcaag tgcaatttcc
     9541 ttagactgtg cattgtcttt atcgatagat ttatcttctc tcggagtatc aagtgctcca
     9601 aaagcaatca atgtctggag tatatgccgg actttggcgt caatggtctc ttccttcacg
     9661 ataccattct ctattgccgg aataagaatc tccctggtca tgaatttacc gacgggcatt
     9721 tccaaatcca accctccatt agcggctccc acaccggaat atacagatgt ccagtcagac
     9781 atcaggatac ctttaaatcc ccactgcttg cgtaatacat caatgttcag ccagctgttt
     9841 tcggtggcat gcaccccgtt cagcggatta tagctatcca tgaccgctcc tactcctgct
     9901 tcctgcacag cttttcggaa cgcgggaaaa taaatttcct gcagcgtgcg ttcatccaca
     9961 tctgagctgg catgatgtct gctccactcc tggttattgg ccgcaaaatg cttcaccgta
    10021 gccataactc cctcttcctg cactcccaag atatattctt tagcagtttc gcccgtcaaa
    10081 taagggtctt caccaaaata ctcatagttt cgcccgcata gaggagagcg gtagatattg
    10141 actccaggcc ccaacagaat acttacccca cgggcctttg catcccgggc caaaccatgt
    10201 cccagctctc tagccaactt acggttccat gtcgaagccg acaagatacc acaaggatac
    10261 agggtacttt gagtattgtt acgtatgcct tgcggaccat cggccatcct gatttcgggt
    10321 atgccaagcc ggggcacagc ccggatataa aaagatttgg gaccggaaat gtaatcgatt
    10381 ttttcttcca gagtcatttg agaaaccaac tccctggcac gctgctccgc ctggggagta
    10441 atacacactt gtgcttttgc cgtgattgca caacaaagca atagcccgct taaggctact
    10501 ttctttttaa tcttcatttt gtctatttta ctacgtgttt gttatattgc cgggcatgtc
    10561 ccgacctact ttctttcttc tcaatcaata aaaaaccgtg tcccttcatc caccaacgaa
    10621 gaaacacggc cgaaagttat taagaaaatt ctgaatctac aagaaagtgg acaaaaacat
    10681 gtctgtcctg ctatcaataa gtaagacgta taccggcctg caacgtaaag ttacacgggt
    10741 tctccttgcg tatagtctgt atcgacgaac cgtcatcaaa gaaataagat actcccggtt
    10801 ccacatacag gcccacccta ttgcttatgt tatactgggc accgacagca cccatgacag
    10861 aaagctgtac cggtttcaca gtctcactct cagtaccaat cttgccatac acacattttt
    10921 caatgacacc ccccgccgaa acgtacatcg taaagttctt tgcatccaca aagttccagt
    10981 tggcccgtac cggaatgcca atataatgca gcttctggct tatcttttcc gagctgccct
    11041 cataccttac gtcagaagca agataggtat acgtcagccc gctttccaca gagaaaccct
    11101 tcgccaagtt tttccgcacc gaaacaccga aactgagcgg ttgtttatgg tctatatccg
    11161 caattttctt ttcgcgtctt tgcagatagg gcataccatc cttaaaaacc agttcctgcc
    11221 cgtcgggaat agtaacaata ccattggccg tagaggataa atctacgtta ccgccataaa
    11281 taggacttcc aggcatgtag cccgacatga cattcgcttc cccttcattc gccaatgaaa
    11341 aacctcccgt atttcctacg gacaagccaa ccgcccatcc tttagcatcc ctaccagaac
    11401 tgtttttttc cggaagatgc agtttgtccc ggcctgacgg acgatagcgg tcttcccttg
    11461 ttctctccgg ttcctctgcc tgcattgtag tttcatggtc cgtatcttcc actaccggtt
    11521 cttccgcctg ctgcccaata ccgacagcct catctgcagt ttcaaccggc agcatttcct
    11581 cctgctgttc ttcgccaacc gatattctga tatgttgtgc aaccaaaggg tgacttgcct
    11641 ccttattggg cgccgatgca tttccatgtg cccgataagc aggctctatg gaattagtcc
    11701 gtatggcagg tactgtctgt tccggcaaga cgtccggagc cacagccaaa gcgggcactg
    11761 acgtatgccg catttcattc cctaccggac tctgcaacag ccacagactg acggacgaaa
    11821 ccgccaccag caacacagct gccgcggcca ccgcccagcg acggaaaggt atcatcctat
    11881 gcggtccggt tatcggagct ccggaaacgg acaattcctt ctccaaccgc tcccatccgg
    11941 caaccggcag cggttcggaa tagtcttcca gcttgtcctt tatctttttc aaccacaatt
    12001 catcttccat acgttccttc atttaatcat ttcttttcat ccactcacgt acttttgccg
    12061 ctaaagtcgc tttagcacgc gtcaactgcg aggcagagga tttttcatta attcccaata
    12121 gtcgagcaat ctccttatgg gatttctctt caaaaatata taagttgaat acggtacgat
    12181 agccggcagg caattcactg ataaactgca tcagtacctt ttgaggaatg acatctattg
    12241 acgaaccttc cggttcctca taagcttcgg gtgcattctc caaggccgat gactgattca
    12301 tcacatcatt tttccgcaaa tactgcaaca ccgtattcac cattacgcgt tccatccatg
    12361 cccgcagaga accctctccc cgccaagtga acttatcgaa agaatcaaaa agtttcagaa
    12421 aaccgtcatg catcaggtct tgggcagtct cccggtcacc tgcataacgg aggcatacgc
    12481 tgagcatgcg tcccgcatag cgctcataca gttctttgcg ggcaagattg tctccttgcc
    12541 tacagcgttc tgccaattcc tgttcttcca ttctctcttt taacacgtgt tcaccctata
    12601 aatgcaatcg gcgcaaaaat actgcatcag gcagagaaga aaatcatact ttcatttctt
    12661 taacagtata ctacgcagta tttagctttt caccgcattt tctgaataca aaaataagtt
    12721 ttaaatagaa aaagagctaa aacctaccac ttatgaagaa actgagaatg acattggcag
    12781 catccatgct tttattcctg actgccattg tattgcaatc atgcctggac gattgggatg
    12841 acaaatatga cactttgttc gccgtaggta cggtaaaggt catcgaagga aaagactact
    12901 atttctcact ggacgaaggc agtaaactat atcccagtga cacaacctat gttcacgact
    12961 atgccgtaat agacggccag agggctttca tctacttccg cgaactggaa gagaaacttc
    13021 caggctacga atacaatgcc caaataaagc acatcgaaaa cattctgacc aaagacatct
    13081 actccatgcc tgccgaaaag gcagacagta tcggagacga caacatcaac gccacggatt
    13141 tatggattac gggcgagtat ctgaacatca aatatcaatt ctaccacagc aacaacgaag
    13201 ataagaagca catgcagaac ctggtcatca atgaagcatc caccggcgaa aacgacaaac
    13261 cggattacgt caatctcgaa ttccgccaca atgcctacaa tgacagccag ctcacgctgg
    13321 gcaccggact ggcctccttc aagctggaca atatagcgga acaactgaaa gagaaaaaag
    13381 ggctgaacat ccgtgtcaaa agtctatatg acggtgaacg gttcatgacc atagacatta
    13441 aaaaagaaaa caactaaatc tcctgaaaac acatctttca acatctcaat gagaagcgga
    13501 gtgacatttc aatatgttgc tccgctttat ttttccatat cccgcttaaa ttcatctttt
    13561 tctttgtcta tccaccggga aacccctaca tttgtaagaa ttttcacaat agcaaacatt
    13621 aaaacggtcc aaaggatatg aaatacatac tgggaacagt aattgcaata ctctgctcgt
    13681 tcacctgcac agacacccta tatggaaaat ctcccgcaac agacgtcgac gatattctga
    13741 taatcaacac ttatacagaa gccaatccct ggagtaatga tttcatcacc tccattgtga
    13801 acatggcatc acagaacagc cacatcggag tatacaccgc acacatgaaa atgctgacac
    13861 ttgacgagga aaataaactg gagacattca aagagagctt gttcaagagt tacaaaaacc
    13921 ctaaacttat cgtgcttatc ggatgcggaa gtttcatcat gtgcgatgaa ctgaaccggc
    13981 agtggcccga tatccccatg atattatgtg gtgagaggga ttataccggt cctaaggaaa
    14041 caatgatacg cgagcacgcc ctgccccgca cagagcgtat tcccatcagt gacctacaga
    14101 agaagtacaa tctgacctta atgcaatcca gtgtatacct gaacgagaac ctgcaactca
    14161 tgaagcaact catccccaaa atggataagg tcatgtatat aggggatgaa acatacatct
    14221 gccagcagaa cgactatgac ttgtccgaga ttatccgtga aaagtatccg gagttggatt
    14281 accagttcct tagtgcgaag gacatccgaa cggacagcct tttcaatata ctgaaccacg
    14341 tgaatcccca tactaccgga gtcatctttt catcctggct gtacaagagc tctccccatg
    14401 acaatatcat gaggagtaat tcccaccggg tcatctctac cgcccccatc cctttgtttt
    14461 cgctaagggc catcggtatt gaagaagaag gggggattgt aggcggctac atttacaaca
    14521 aagagaaata taatgcccgg ctactagaaa ccatccacaa gatattggat ggtaccccgg
    14581 cacgcaacat cccgttatac tatcccgacg acggagcccc cgtattcaac tataaatccc
    14641 ttctgcagcg tgacctgaat ccgaagctat gccccaaggg taccatattc tacaacatgc
    14701 ctcccacctt ctgggagaag tacgaatatg tcattatcag tatcactgcc gcaatcataa
    14761 ctctgctgtt ctttttccaa tatctccgcc tacagtcact gagtagaatt aaaagattac
    14821 aacagcaaca actggacagc aatctcaaat accgaaatct gataaacaac atgcccatcc
    14881 tatacatgta tgagaaactt ataaaagatg aaaaagggcg cattactgac accttatata
    14941 tagatgtcaa caatttcttc gaagacagat ttatcatgcg caaagaggct gtcggcaagc
    15001 ggggaagcga attatttccc gaatccatga acgagttcct ccatttcatg aatattgcat
    15061 tgaaggagaa acgttccgta actttcccct attattacaa gaagatagac actttctacg
    15121 acattgtagt caaggcaagc gacaatggcg aatacatgca cgtcttctgc gttgacagca
    15181 ccgagttgca ccacacccaa atacagttga ggtcgacaaa ccggaaactt tccatggcac
    15241 tcgacgttgc caacatcgta ccatggaaat ggaacctccg gacacacacc atactctgcg
    15301 atgtcaacaa gccgatagag ctcagcaata atgccggtat catggacgat gaacagctgt
    15361 ccgtacccga cagccagtat ttctccaaaa tacacaagga agacctggaa aaagtgaaac
    15421 aagcctatac agacctgatt gagggacgta tccagaaagt caaggaggaa taccgcgtca
    15481 tcaatcatgc cgacggacac aaacacttcg actgggtgga ggcccaggcc gccgtagaaa
    15541 cctacgacga gaacaataag ccgctgaccc tggtgggctc ttcgctggtt atcaccgaac
    15601 ggaaaaagat ggagacggaa ctggtttccg ccaagaaccg tgcggaagag tcgaataaac
    15661 tgaaatccgc attcctcgcc aacatgagcc atgaaatccg tacgccgctc aatgccattg
    15721 tgggattctc cggaatattg gcttccaccg a
//
