LOCUS       gnlProkkaGECAGFMN_98   10813 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GECAGFMN_98.
ACCESSION   gnlProkkaGECAGFMN_98
VERSION     gnlProkkaGECAGFMN_98
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-18 11:33:54
            Original ID  :: gnl|Prokka|GECAGFMN_98
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10813
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10813
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[9791:10043]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      9792..10043
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..10813
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10813
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             complement(3..959)
                     /locus_tag="ctg98_1"
                     /transl_table=11
                     /translation="MAGIGVKLQKIYDRRTILANLAGFGYSTMVTIAPMFVVIGNVMLM
                     SHFLGYETVGYARRGLFSGTVLYIFIFSLLVAAPFNAVLSRYMSDIIYEEKYEDILPCY
                     DVGLFLNICFGCLFAIPFCVREYLKGQVDLVFVFTGFCGFISLLLVFYSMLYLSICKDY
                     QKISLFFLIGMAAAFGLAWLLVKVFHRDIIYSMLLSLTIGFFLTAAISAATIKSYFKRN
                     SRQYRKVLHYFKIYWHLIATNLLYTLGLYIHNFIFWTTDLKMTVAHTFVYAPAYDMATC
                     LAMFTNLSSTIIFISRVEMHFHERYKAYSEAVIGGRWE"
     CDS             complement(963..2405)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045:glycosyl transferase group 1 (Score: 117.4;
                     E-value: 1.5e-35)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg98_2"
                     /sec_met_domain="Glycos_transf_1 (E-value: 1.1e-26,
                     bitscore: 82.6, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVCIVAEGCYPYVVGGVSSWINSMIKAFPDIEFVVLAIVANRSY
                     RGKFVYELPENVSEVYELYLEDYDWVEQEKNKKLHLRQNEYEALRSLLLNRDVEWDTLF
                     TLFEKKNFSLNALLMGEDFLNAVRECYQLRYSQVVFSDFLWTMRSIYLPLFLTLKMELP
                     EADLYHCVATGYAGVIGSMAKKRYGCGLMVSEHGIYTREREEELIRAKWVGGIYKNIWI
                     EQFKKMSLLAYRYADQVTCLYKHAMELQIELGCPAEKIKITPNGIDDQRFVRCLEEERK
                     EDDTINIGAVLRIAPIKDVKTMIRAFAYAKKEAPKLALWIMGPSDEEKEYAKECFELVD
                     LLGVEDVIFTGKVDVTEYLGKMDMTILTSISEGQPLTILESFAAKKPVIATDVGNCRGL
                     IYGEGDSFGEAGIITHIMNVEEIAAAMVDLACHREKRIGMGKNGYRRLKSRYLVEDMKE
                     TYRQIYRQFEDEGRVQGKKGDV"
     CDS             complement(2408..4225)
                     /locus_tag="ctg98_3"
                     /transl_table=11
                     /translation="MVSRRNFAAITIMLIILLFMFQFTGVMKDKLSKYGINEYKESATT
                     ELTKQDMYLASGQNIQKTAGVLYIGNSEAVKNTVKWWCTYSKREFQTADSFDGIVSEDS
                     RLTDILVLDGTCLNTRDNIKAVSDAAEKGVNVIVSGLPDAEEIEKNDRLRKLLGIRYVE
                     QNEVTLDGIHLFEGFLLGGEVIYQAKDEKEEKNQDMDLKIPWYVTREGTKSYMVGILSD
                     VRPDSGRQPAIIWRNGLENACVFCINGNYLKDNSGIGILDAMMAESYSFEIYPVINAQN
                     LVIANYPGFASENENKMEKIYSQSQKALFREIIWPSLVAIERKIDAKLTCMMTPQFDYG
                     DENEPREGEVAYYLKLLKEEYGEAGLSSGNVSGTGLSEKMEKDETFWKKEAPDYCFQSL
                     YLQNEDELGDALECEELDGIRTIVTRESQTSDEPIVSFAGEEVTLQRATGDGVNHTFMD
                     DFRQRCIQTALGYSNTVWDLLAAAYPEKKDDAWEILSKEAASNICTYQKPFTAFDETTI
                     SKSDQRIRRFLALSYSAESEDNMISLHVDGLEEEAWFLLHTGTREAEDIQGGSFSVVED
                     GVYLICAEEDEVKIRLSEEEEKQLFYYED"
     CDS             complement(4276..6678)
                     /locus_tag="ctg98_4"
                     /transl_table=11
                     /translation="MSMKVLTVLQFISIFTIYTGLFIAVPALLLHRRLKDEIFSVRFFF
                     YIVLGHFYLINLVLFLQLLHISGRFTLILGSALPVVISLVHTKRVSPKKIGHIIGNRTS
                     HVIRETLGIKLLLLEIVQWIGRKIKKLCGRMCGLIIRHFADGVLFVVFTATVLVMYGTN
                     MINTYGYCASDIPVHNYWINAMGQNDVFVAGIYPFGFHCVIYYIHTVTGIETYVLLRLF
                     YVVQVLYIHYALLAFLKACCRTSYCAWGAVFVYVLAAFFNRNTYSRYYSSLPQEFGMIF
                     ILPGIYFMYAFLKQRKIEVNQCKKERNAAGLKTWKCKSTRYLMGFIAGFGLTLIVHFYD
                     TMVAGLFCIGIAGGYLLRIFKKEYFFRVLATGLLSIFLAVFPMGIAFLQGTPLQGSLGW
                     GLNVINGSNNTGAEEEDEADIPGSEKEEINTNTQSVTDQSMTESTDTAGSMTDQTMSEN
                     GVENAQMTEGTQVKTTRFGMLVEKIRFRITDITQNGLDYLWTGVHNVVMLQASVPWMLF
                     IFGCEGFCLIGGLLFTLIGKHDYGSMLMSAGFGLLLLMMFLSAWRFGLPHIMDASRCSI
                     YVAYMIPVAIGLGMDGMVTLVFGFFKRNIWMNLVSLMTSAALVATLVNGNQIRTPSILT
                     ALQSNAAITCLANIKRENEKYKYTICSANDELRMMEDYARHEETITFLRSMEGDAVNGN
                     LTLPTDRVYFFIEKIPLDYTVAYEGSGQLISEEGAKKPLPTAGDISVYEGENRWIVMSR
                     MYYWAQAFMELYGKEMQVYYETDDFICYVVEQNTYSLYDFSIDYGYN"
     CDS             complement(6693..7604)
                     /locus_tag="ctg98_5"
                     /transl_table=11
                     /translation="MTVVEKRFCIVLLINTAVAVLYVIGNSRIRQKEKNTDILMKGIMM
                     FLCPVVGPLFFLAGLVFNKVFFRQNVDLEDVIFSKERVKTHLRADEEREGNLVPIEEAL
                     AISDKDSLRTLVMNVVRGDVQNSLASISLALNSEDTETSHYAATVLRDALNDFRKRAQE
                     LYLQMKQEGVDAAEAACILIEYMHGVLIQEVFHEKEQQTYIDMMEEACNFLDEKYQEKL
                     QASYIEGLCVLLLKIKDFKRMKYWCDKSRELYPAELSTYTCYLKLYFTEGNKKHFFDEL
                     EKLKNSDIVIDRETVELIRIFS"
     CDS             complement(7601..9778)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score: 79.5;
                     E-value: 4.8e-24)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg98_6"
                     /sec_met_domain="RmlD_sub_bind (E-value: 1.4e-20, bitscore:
                     62.6, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNILLVGNAGNFMRLMINRLNKEGHRVFVLTEEPKKGYSLKKVFE
                     VYHFSYEDACVREVLESIMPQVVVFLGAYDHNFSWNRVENTAASYAAGLTNILMNYTAL
                     KKGRFVYLSSESVFGGGSAQFMTEDDPTGAYSKKGQAIAIGEDICKNYARMGNDVVILR
                     LDHLYGEIRKKEDTDTICADMCLEAVQTGEIIASQNEKIMLLHEADAVEFIYQIMVAKD
                     HKHTLYQLSSGEKMSRYELAQAVAAGMENEVSIVEEENKKYREVMLSGKRYDEEFGSRV
                     LHHAGTDVEKIAAYFSRHVSEFTDAGQKKGHLFRRLGSRTKEIITNLIPFMENLICFIP
                     FFMLNNRAVGSEYFQNIDFYLLYVLLFALVYGQQQATFSALLAVAGYCFRQMYHRSGFD
                     VMLDYNTYVWIAQLLILGLAVGYLRDQLRAMREEQRHEVSYLTKQLDDISDINVSNVRV
                     KEILANQIVNQNDSFGKLYEITSSLEQYEPCEVLFYAAEVLAKLMGSKDVAIYTVANRS
                     YARLFSATSEKARSLGNSINYSEMDAMYTVLAEKKVYINKNMDERYPLMANAIYSEDEM
                     QLILMIWGIPWERMTLGQANMLTVIGYLIQNAVVRANRYISALEQQRYIKGTNILEPEA
                     FLALVKAYLNARDKGLTQCALLSVDTKENDRDEVGKRLIKLLRQSDYVGELEGGKMYAL
                     LANTSAKDATMVRERFEKEGVSCQIQEDVFV"
     CDS             complement(9792..10043)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg98_7"
                     /sec_met_domain="PF05402 (E-value: 2e-15, bitscore: 46.1,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 9.7e-12,
                     bitscore: 34.0, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKERYQLRQAAGAYWLLDMEQGEQYKKPFMLNECGAYIYRAYISG
                     MSEDEIMQAFAKEYGLSFSCAQSDVGQFMMELRQRGII"
     CDS             complement(10084..10812)
                     /locus_tag="ctg98_8"
                     /transl_table=11
                     /translation="MIGVGADGILYGPVMEDKKIKVRIFNPDGSEAEKSGNGIRIFSRY
                     LKDAGYVKERQYYLTTKAGETLVTFLDDAGSCMRVDMGYAVFEAEQIPALGFEGEVVGE
                     SIFFCDNFYNATCVSMGNPNCVIMLERVDREKALRLGPYVENAKYFPNRINMQLCQIVD
                     EKNIQVEIYERGAGYTFASGTGACAAAAASHRLGLVEDAVTVHMHGGDLFIEFEKDGRI
                     FMTGPVVYIGKITVAEQFFA"
ORIGIN
        1 tcttcccatc tgccaccgat aacagcctcc gaatatgcct tgtacctctc atgaaaatgc
       61 atttccacgc ggctgataaa aatgatggtc gacgaaagat tcgtaaacat tgccagacag
      121 gtcgccatat catatgcagg cgcatagaca aacgtatgtg ccaccgtcat ctttaagtcc
      181 gtcgtccaga atataaaatt atgtatatac aatcctaacg tatacaatag gtttgtcgca
      241 ataaggtgcc agtaaatttt gaaataatga agcaccttgc ggtactggcg gctgttcctt
      301 ttaaaataac tcttaatcgt tgccgctgat atcgccgccg tcaggaaaaa tccgatcgta
      361 agtgaaagaa gcatgctgta tatgatgtcc ctgtgaaaca ctttcacgag cagccacgca
      421 agcccaaatg ccgctgccat accaatcagg aaaaataatg atattttctg atagtccttg
      481 cagatcgaca gatacagcat ggaataaaat accagaagaa gcgatataaa gccgcaaaac
      541 ccggtaaaca caaacaccag atccacctgc cccttcagat actctctgac acagaacggg
      601 attgcaaaca gacacccgaa acaaatattt aaaaataatc cgacatcata acatggcagg
      661 atatcttcgt acttttcctc ataaataata tcggacatat atctcgataa tacagcatta
      721 aacggtgccg caaccagcag ggaaaatata aaaatataaa gtaccgtgcc tgaaaataat
      781 cctcttctcg cataccctac tgtctcgtat ccaagaaaat ggctcattag catcacattt
      841 ccgatcacga caaacatggg tgcgatcgtg accatggtac tgtaaccgaa tcctgccaga
      901 tttgcaagga tcgtgcgcct gtcataaatt ttctgaagtt ttacgcctat tcctgccata
      961 gatcacacat cccctttctt tccctgcact ctgccttcat cctcaaattg ccggtaaatc
     1021 tgccggtatg tttctttcat atcctccaca agataccggc tctttagtct ccggtatccg
     1081 ttttttccca tgccaatcct cttttctctg tggcatgcca gatctaccat cgctgccgca
     1141 atctcctcca cattcatgat atgtgtaatg atcccggctt ccccaaatga atcgccttcc
     1201 ccgtagatca gccccctgca gttgcctaca tccgttgcaa tcaccggttt ttttgccgca
     1261 aaactctcta agatcgtcag tggctgtccc tcactgatgc ttgtgagtat ggtcatatcc
     1321 atcttcccaa gatattctgt cacatcgact tttccggtaa agatcacatc ctccacgcca
     1381 agaagatcca ccagttcaaa acattctttg gcatattctt tttcctcatc ggatggtccc
     1441 atgatccaca atgcgagttt tggtgcctct ttcttggcat aagcaaaggc tcttatcatc
     1501 gttttgacat ccttgatcgg cgcaattctt aacaccgctc cgatattgat ggtgtcatct
     1561 tcttttctct cttcttcaag acatctgaca aatctctgat catcaatacc gttcggtgtg
     1621 atctttattt tttctgccgg acatccgagt tcgatctgaa gttccatggc atgcttgtaa
     1681 agacaggtta cctgatctgc ataccggtat gcgagcaggg acattttttt aaactgttcg
     1741 atccagatat ttttatagat accgcctacc cactttgcac ggatcagctc ctcctcccgc
     1801 tccctggtat aaattccatg ctccgaaacc attagtccgc atccatatct tttttttgcc
     1861 atgcttccga tcactcccgc atatccggtc gcaacacagt gataaagatc cgcctcgggc
     1921 agttccattt tcaaggtcag aaacagtggc agataaatgg aacgcatggt ccagagaaaa
     1981 tcagaaaaaa caacctgtga atatctgagc tgataacatt cccgcacagc atttaaaaaa
     2041 tcttctccca tcaaaagcgc gttcaatgaa aaatttttct tttcaaacaa cgtaaacaac
     2101 gtatcccact caacatcccg gtttaaaagt aatgaccgca gtgcctcata ttcattctga
     2161 cgcagatgca gttttttatt tttttcctgc tctacccagt cataatcttc cagataaagc
     2221 tcataaactt ccgacacatt ttccggcagt tcataaacaa attttcctct gtatgaacgg
     2281 tttgccacaa tcgcaagcac cacgaattct atgtcgggaa aagcttttat catactgttg
     2341 atccaactgg aaacaccgcc caccacataa ggataacatc cctctgctac aatacatact
     2401 ttcattttca atcctcgtaa taaaacaatt gcttttcttc ttcctcactc aaccggattt
     2461 ttacctcatc ctcttctgca cagatcaggt aaacaccatc ctccactaca gaaaaacttc
     2521 ctccctgtat atcctctgct tcgcgtgttc ccgtatgcag taaaaaccat gcttcctctt
     2581 ctaatccgtc aacatgcagg gaaatcatat tatcttcaga ttctgctgaa taagaaagtg
     2641 ccagaaatct ccttatcctc tgatcgctct ttgagatcgt tgtctcatca aatgccgtaa
     2701 acggtttctg ataagtacag atattagacg ctgcttcctt cgaaaggatc tcccacgcat
     2761 catccttttt ctccggatat gctgctgcaa gcagatccca taccgtattc gaatacccca
     2821 atgcggtctg gatacatctc tgtctgaaat catccataaa tgtatgattc acaccatctc
     2881 cggtagcacg ctgcagtgtc acctcttccc ctgcaaagga aacgatcggt tcgtcgctgg
     2941 tctgtgattc cctggttaca atcgtcctta ttccatcaag ttcctcgcat tccaaagcat
     3001 cccccagttc gtcttcattt tgcaggtata atgactgaaa acaataatct ggtgcctctt
     3061 ttttccaaaa cgtttcgtct ttctccattt tttccgacag cccggttcca gatacattgc
     3121 cggatgaaag tcctgcctcc ccgtattctt ctttcaataa tttcagataa tatgccactt
     3181 ctccctcccg tggctcattt tcatctccat aatcaaactg cggtgtcatc atacaggtca
     3241 gttttgcatc gatctttcgt tcaattgcga ccagcgacgg ccagatgatt tctcgaaata
     3301 atgccttttg tgactgactg tatatttttt ccattttatt ttcattttcc gacgcaaatc
     3361 caggataatt tgcaatcaca agattctgtg cattgatcac cgggtaaatc tcaaacgaat
     3421 acgattctgc catcattgca tccagaatgc caataccgga attatccttt aaataatttc
     3481 cattaatgca aaacacacag gcattttcca gtccgtttct ccatataatg gcaggctgtc
     3541 ttccgctgtc cggccgaaca tctgagagta ttccgaccat ataacttttt gtgccctccc
     3601 tcgtcacata ccatggaatt ttaagatcca tatcctgatt tttctcttct ttctcatctt
     3661 ttgcctgata gatcacttcc ccgccgagca gaaatccttc aaacaagtgt atgccgtcaa
     3721 gtgtcacttc attctgttcc acatatcgga ttccaagcag ctttctcaaa cggtcgttct
     3781 tctcaatttc ctctgcatcc ggcagtcctg aaactataac atttactccc ttttcggctg
     3841 catcactgac cgcctttata ttatccctgg tattcagaca ggttccatct aaaaccaaaa
     3901 tatccgtcag cctgctgtct tccgacacga taccatcaaa agagtccgct gtctgaaatt
     3961 cacgtttgct atatgtacac caccatttta cggtattctt tactgcctca ctgtttccaa
     4021 tatacagcac acctgctgtt ttctgtatat tctgcccgga tgccagatac atatcctgtt
     4081 ttgtcagttc cgttgtggca ctttccttgt attcattgat cccatattta cttaatttat
     4141 ccttcatcac acccgtaaat tgaaacataa acagtaaaat aattaacatg atcgtgattg
     4201 cagcaaaatt tcttcgggat accatcacat tttcctttcc aaatccatct catcctgcag
     4261 ccattatttt ttccgtcaat tatatccata atcgattgaa aaatcatata aactgtaggt
     4321 attctgttct accacatagc agataaaatc atctgtttca taatacacct gcatttcttt
     4381 tccatacagt tccataaatg cctgtgccca gtaatacatt cttgacatta cgatccatcg
     4441 gttttcacct tcataaaccg aaatatctcc tgctgttggc agcggttttt ttgctccttc
     4501 ttctgaaatg agctgtccgc ttccctcata tgccacggta taatcaagtg gtatcttctc
     4561 aataaagaaa tatacgcggt ctgtcggcag cgtcagattt ccattgaccg catctccttc
     4621 catactccgt aaaaatgtaa ttgtttcctc atgacgtgca taatcttcca tcattcgcag
     4681 ttcatcattc gcagaacaga ttgtatattt atacttttcg ttctcccgct ttatatttgc
     4741 cagacaggta atcgccgcat tcgactgcag tgccgtcaat attgacggtg tacggatctg
     4801 atttccattg acaagtgtcg caacaagtgc cgctgacgtc atcagtgaaa caagattcat
     4861 ccagatattc cgcttaaaaa atccaaagac caatgttacc ataccgtcca ttccaagtcc
     4921 gatcgctacc ggtatcatat aagcgacgta gatactgcac cggcttgcat ccatgatatg
     4981 tggcagtcca aaacgccatg cagaaagaaa catcatcaaa agcagcagac caaatcctgc
     5041 ggacatcagc attgatccat aatcatgttt tccaatgagc gtaaacaata gtccaccgat
     5101 caggcagaat ccctcgcacc caaaaataaa caacatccat ggcacgcttg cctgaagcat
     5161 tacaacattg tgcactcctg tccacagata atccaatccg ttttgggtaa tatccgtaat
     5221 ccggaaacgt atcttttcca ccagcatacc aaaccttgtt gtttttacct gcgtcccttc
     5281 tgtcatctgt gcattttcca caccattttc tgacattgtc tgatccgtca tgctcccggc
     5341 agtatccgta ctttccgtca tgctctgatc cgtcacactc tgtgtatttg tatttatttc
     5401 ttccttttca ctgccaggga tatctgcttc atcttcctcc tcagcacccg tattattgct
     5461 gccattaatt acattgagtc cccagcccag cgatccctgt aaaggcgtac cctgtaaaaa
     5521 ggcaattccc atcggaaaca ctgccaagaa gatacttaaa agaccagtcg caagaaccct
     5581 gaaaaaatac tcctttttga aaatacgcaa caggtatcct cctgcaatac cgatacagaa
     5641 caaccctgct accatagtat cataaaaatg tacgatcagc gtaagtccaa atcctgcaat
     5701 aaatcccata agataacggg tacttttgca tttccaggtt tttaatccgg cagcgtttct
     5761 ttcctttttg cattgattca cttctatctt ccgctgtttt aaaaaggcat acataaaata
     5821 aatgccgggc aggataaata tcatgccaaa ttcctgaggc agcgaactgt aataacgcga
     5881 gtaagtattc ctgttaaaaa atgcagcaag tacatagaca aatacagctc cccatgcgca
     5941 atacgatgtc ctgcagcacg ctttcaaaaa tgccagaagt gcataatgga tatataagac
     6001 ctgcaccaca taaaaaagcc ggagcagcac atacgtttca atccctgtta ccgtatggat
     6061 ataataaatt acgcagtgga atccaaatgg ataaattcca gctacaaaca catcattctg
     6121 ccccatcgca ttgatccagt aattgtgtac cggtatatcg gatgcacaat aaccgtatgt
     6181 atttatcata ttggttccat acattaccag aaccgttgca gtaaatacaa caaacagcac
     6241 tccatctgca aaatgcctga tgatcagccc acacattctg ccacacagtt tcttaatttt
     6301 tctgccaatc cactgtacaa tctccagaag aagtaattta atgccaagcg tctcccggat
     6361 cacatgggat gttctgtttc ctatgatatg tccgattttt ttaggtgaaa ctcttttcgt
     6421 atgtaccaag gatataacga ctggaagtgc actgcccaaa atcagcgtaa atctgcctga
     6481 aatatgaagc agctgaagaa ataataccag attgatcaga tagaaatgac ctaatacgat
     6541 ataaaagaaa aaccgtacac taaatatttc atcttttaac ctgcggtgca gaagcagtgc
     6601 cggaactgcg ataaaaagtc ccgtataaat tgtgaaaatg ctgataaact gtaacacagt
     6661 caggactttc atcgacactg ccatcaccta ctttagctaa aaatacgaat taattccact
     6721 gtttccctgt cgatcacaat atctgaattt tttaattttt ccaattcatc aaaaaaatgt
     6781 tttttgtttc cctctgtaaa ataaagtttt aaataacagg tataggtaga taattctgcc
     6841 ggatagagtt ccctgctctt atcgcaccag tatttcatgc gcttaaaatc ctttatctta
     6901 agaagcagaa cgcaaagtcc ctcaatatag gaagcctgca gtttctcctg gtatttttca
     6961 tccagaaaat tacatgcctc ctccatcata tcgatgtagg tctgctgttc cttttcatga
     7021 aacacctcct ggatcaatac cccatgcata tactcaatca ggatacaggc tgcttctgcc
     7081 gcatcaactc cctcctgttt catctgaagg taaagttcct gtgcacgctt tctgaaatca
     7141 ttcaatgcat cccttaatac tgtagcggca taatgtgatg tttccgtgtc ctcactgttt
     7201 aacgcaagcg agatggatgc cagagaattc tgtacatccc cacggaccac attcatgacc
     7261 agcgttctta aactgtcttt gtcgctgatc gcaagtgcct cctcaatcgg tactaaattt
     7321 ccttcccttt cctcatctgc ccgaagatgt gtctttacac gctccttgct gaaaataaca
     7381 tcctcaagat ccacgttctg ccggaaaaaa accttgttaa acaccagtcc cgccaaaaaa
     7441 aacaacggtc ccactaccgg gcagagaaac atcatgatcc ccttcatcag aatatctgta
     7501 tttttttctt tctgcctgat cctgctgttt cctatcacat ataaaacagc aacagccgta
     7561 ttgatcagaa gaacgataca aaatctcttt tccacaaccg tcatacaaat acatcctcct
     7621 gtatctggca ggacacaccc tctttttcaa atctttctct taccatggtt gcatcttttg
     7681 cactggtatt tgcaagaagc gcatacattt ttccaccttc aagttcaccg acataatcgc
     7741 tttgtctaag gagtttaata agccttttcc cgacctcatc acggtcattt tcctttgtat
     7801 ccacggaaag cagtgcacac tgtgtcaatc ctttatcacg cgcatttaaa tatgccttta
     7861 caagtgctaa aaaggcttcc ggttctaata tattcgttcc ttttatgtaa cgctgctgct
     7921 ctaaggcaga aatataacgg tttgcacgca ccaccgcatt ctgaatcaga taaccgataa
     7981 ccgtcagcat attcgcctgt cctaacgtca tccgctccca cggaattccc cagatcatca
     8041 gaatcagctg catctcatcc tccgaataaa tggcatttgc cataagcgga tatctttcat
     8101 ccatattttt attaatataa actttcttct cggcaagcac cgtatacatg gcatccattt
     8161 cgctgtaatt gattgaatta ccgaggctgc gtgctttctc cgatgttgca gaaaaaagac
     8221 gtgcatagga acggtttgcc accgtataga ttgccacatc tttgcttccc atcagttttg
     8281 caagtacttc cgccgcataa aaaagtacct cacagggttc atactgctct aaactggatg
     8341 tgatctcata taattttcca aaactgtcat tctggtttac gatctggttt gcgagaattt
     8401 cttttaccct gacattgctg acattgatat ccgaaatatc atctaactgc ttggttaagt
     8461 atgatacttc atgccgctgt tcctccctca ttgcacgaag ctggtctctc agatatccca
     8521 ctgccagacc taagatcaaa agctgcgcga tccagacata ggtattatag tcaagcataa
     8581 catcaaatcc gcttctgtgg tacatctgcc ggaaacagta ccctgccacg gcaagcaatg
     8641 cagaaaatgt tgcctgctgc tgcccgtata caagtgcaaa caacagcaca tacagaagat
     8701 aaaaatcaat attctgaaag tattcacttc cgactgcacg gttattcaac atgaaaaacg
     8761 gaataaaaca aatcaggttt tccataaaag gaatcagatt cgttatgatt tcctttgtcc
     8821 tgctgcctaa tcttcgaaac agatgtccct ttttctgccc tgcatctgta aattcagata
     8881 catgtctgct gaaataagcc gcaatctttt ccacatctgt tcctgcatga tgaagcacac
     8941 ggcttccaaa ttcttcatcg tatcttttac cggaaagcat aacttcccgg tattttttgt
     9001 tttcctcttc tacgatactg acctcattct ccattcctgc ggcaacagcc tgggcaagct
     9061 cataccgtga cattttctcc ccggaagata actgatagag ggtatgttta tggtcttttg
     9121 ccaccattat ctggtagata aactccaccg catccgcctc atgcagaagc attatttttt
     9181 cattctgcga cgcaatgatc tctccagtct ggactgcttc gaggcacata tccgcacaga
     9241 tcgtatctgt atcctctttc tttcgtattt ccccatacaa atgatcgagg cggagaatca
     9301 caacatcatt ccccatcctt gcataatttt tacagatatc ttctccgata gcgatcgcct
     9361 ggcctttctt gctgtatgcc ccggtaggat catcctctgt cataaactgt gcgcttccac
     9421 cgccaaaaac actctccgaa gaaagataga caaacctgcc tttctttaaa gcggtataat
     9481 tcatcagtat attcgtaagt cccgctgcat aggacgccgc tgtgttttcc accctgttcc
     9541 aggaaaaatt atggtcatat gcccccagaa aaactactac ctgtggcata atactctcta
     9601 atacctcccg cacacaggca tcctcatacg aaaaatgata cacttcaaat actttcttca
     9661 ggctgtatcc cttctttggt tcttctgtca gtacaaagac cctgtgtcct tccttattca
     9721 gtctgttgat cataagccgc ataaaatttc cggcattccc aactagcaat atattcatac
     9781 ctgctccatt ctcaaataat tccccgttgt cttaactcca tcataaactg ccctacgtcg
     9841 ctttgtgcgc aggagaatga caatccatat tcttttgcaa atgcctgcat gatctcatcc
     9901 tcagacattc ctgaaatata cgcacgatat atatatgcac cgcactcgtt caacatgaat
     9961 ggttttttat attgttcccc ctgctccata tccaaaagcc agtatgcccc cgctgcctgg
    10021 cgtaattgat accgttcttt cattgtaact tatttcccct cttttcgcca ctttcgtttt
    10081 ctgtcaggca aaaaactgtt ctgccacagt aatctttcct atatatacga ccggtcctgt
    10141 catgaaaatt cttccatcct tttcaaattc gataaaaaga tctccaccgt gcatatgtac
    10201 ggtcactgca tcttcgacta atcccagacg gtgagaagcc gctgctgccg cacaggctcc
    10261 ggtgccggaa gcaaatgtat accccgcccc gcgttcataa atttcaacct gtatattttt
    10321 ttcatctacg atctgacaaa gctgcatatt gatacggttt ggaaaatatt ttgcattttc
    10381 cacatatggt cctaaacgca gtgctttctc acgatctacc ctctcaagca taataacaca
    10441 atttggattt cccatggata cacaggtcgc attataaaaa ttgtcgcaga aaaatatcga
    10501 ttctcccaca acttctccct caaatccaag tgccgggatc tgttctgcct caaagaccgc
    10561 atatcccata tccacacgca tacagcttcc agcatcatcc aaaaatgtta ccagtgtttc
    10621 ccccgctttc gtggtcagat aatattgcct ttcttttaca tatccggcat cttttaaata
    10681 tcttgaaaaa atccggatgc cattgccgct tttttcagct tcacttccat ccggattaaa
    10741 aattcgtact ttaatttttt tatcttccat aaccggtccg tacaaaattc catctgcacc
    10801 gacaccaata ttg
//
