LOCUS       c00020_gnlPro..        24638 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PKPLCHIH_20.
ACCESSION   c00020_gnlPro..
VERSION     c00020_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 19:53:22
            Original ID  :: gnl|Prokka|PKPLCHIH_20
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 20295
            Orig. end    :: 44933
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24638
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[30295:34933]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14638
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..24638
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..24638
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             complement(1044..3776)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg20_15"
                     /sec_met_domain="Peripla_BP_1 (E-value: 1.1e-07, bitscore:
                     23.5, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKPALTYYALLVLLLASCFSCKTDSEKKKFVIGVSQCTLEGSWRK
                     SMLLDMKVQASEYPGVSLLVEDAADSSLLQVEQIRSLIKRKVDLLIISANESEPVTPIA
                     IEAYRAGIPTILVDRKISSDEYTTYIGGNNYEIGRQAGFFVNRQVKEKYPTVLEVWGLS
                     GSSPAQDRHRGFMEVLNSRIKVKEIFGKWKPETVEKEIAEMDLLEEVDVVFAHNDVMAM
                     AARRAIERMHPGLADRICFVGIDAVSGRGSGLEAVMHGELAASVLYPTGGSLAIRVAMQ
                     ILNGEDVSRQYLLSSALIDKNNAGTLFIQSEQVVDYQHQIELQRENLESMLSKYTFLQN
                     SVGIILLLMGMLLLSALYVIHVNRAVKRKNRELKRTNLQVQQQKEELAEANRYIEKSTA
                     QKLQFFTNITHEIKTPLTLILGPLGKLSKEAPEGSSLADDIRIIRKNAERLKRVVDQLL
                     DFRKVESNKMNMRVGEVDLVAFVAEVKSYFDTMAATKQIHFTFEHDCPSVNIWVDRDKM
                     EKILANLLSNAFKFTLDGGTVTIRLKDKGDQVELSVEDNGKGIPSENIASVFDRFFTGD
                     QNYVTGTGIGLHLTREFVHMHKGTIRVESVPHKSTVFTVILLKGKSHFDESCIFDLSVT
                     ELSSGVADLNTDELQEVLNRTYNYTVLVVEDDLDIQSYLQAELKQNFRVLVADNGVKAL
                     EVLMNEDISMVISDVMMPEMNGFDLCRKIKSDIVLSHLPVMLLTALSDDKQQMYGAASG
                     ADAYIQKPFNIEVVKLRIIKLLEDRVRLREAYARDASSPAVSVKEEKAGSMDDLFMNRF
                     LKLIEESYADPDFSIEKGSEKLGLSRVHLYRKVKELAGVTPTDFLRNYRLKKAAALLRR
                     KAGNVNEVAYATGFGSPAYFSKCFKAVYNITPTEYLEKE"
     CDS             3873..4340
                     /locus_tag="ctg20_16"
                     /transl_table=11
                     /translation="MKIINEALLDETTGRAKQSPRLRMNYNFHEHLDDPVNRLLNALEP
                     GTYLRPHRHLNPKKDEIFLLLRGRIAVFLFDNKGEITQTQILDPKEGVYGAEIKAGTWH
                     GLLVLESGSVIYEIKEGPFAPLAPENFAPWSPAPEDTKGVAKYMELLGKAI"
     CDS             complement(4558..6387)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_U32"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg20_17"
                     /sec_met_domain="Peptidase_U32 (E-value: 2.3e-73, bitscore:
                     238.0, seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQTKSRPIELLSPAKDLNCGIEAINHGADAVYIGAPKFGARSAAG
                     NSLEDIRELCEYAHLYEARIYVTLNTILKEDELEEAERMIWDLWRVGTDALIIQDMGIT
                     RLNLPPIPLHASTQTDNRTPEKVRFLEAAGFTQVVLARELSLNEIRRISEATTVPLEVF
                     VHGALCVSYSGQCYLSAALSGRSANRGECAQYCRLPYTMVDATGTEIVTHKHLLSLKDM
                     NRSDQLEALLDAGVSSLKIEGRLKDAGYVKNITAYYRKKLDAVLSRRPEYRRASAGRST
                     YTFEPVAEKSFNRGLTPFLLEGRTADITAFNTPKSLGEPVGTVKEIKGNSFTVAGLKQL
                     NNGDGLVFFNRKGELEGFRVNRVEANRVFPLDMPQLAPKTPLYRNFDQAFDKLLAKPSA
                     ERKLSVEIEFLDNPFGFTLCMEDETGARIMLTEPFAKELARREQQDNIRTQLSRLGNTP
                     FEASKVVVGLFENWFVPSSLLADMRRRGVEKLLEARRARYPRETVKRVQPSVSIPFPER
                     QLTYLGNVANGKARSFYQDHGVEQIDPAFELSPRKDVPLMFTKHCLRYSMGWCPTYQKD
                     KSPYKEPYYLLYKDTRLRLQFDCKHCQMLVFES"
     CDS             complement(6410..7342)
                     /locus_tag="ctg20_18"
                     /transl_table=11
                     /translation="MPLNLQKNLPAVELLKKEHIFVMDSLRASEQDIRPLRVVVLNLMP
                     LKITTETDLVRLLSNTPLQVELDFMKIKGHTPKNTPIEHMKEFYKDFDEMQDDFYDGMI
                     ITGAPVEQMPFEEVNYWEEVTEIFDWARTHVTSTLYICWAAQAGLYHFYGVPKYDLPAK
                     MFGVFRHTLREPYVPIFRGFDDEFYVPHSRHTEIRREDVMKVPDLTLLSESEESGVYMA
                     MARGGREFFITGHSEYSPYTLNDEYMRDVNKGLPIAVPRNYYRNNNPALGPVVRWRGHA
                     NLLFTNWLNYYVYQETPFRIEDISKLGDL"
     CDS             7451..9856
                     /locus_tag="ctg20_19"
                     /transl_table=11
                     /translation="MKIRAIATLLFILFSISAFGQGRAKISGYIRDADGNPLDLVNIRV
                     KNTLNGTMSNEKGHYSLSVATGDSVTLIYSCLGYNKAERILPQVTKDMRLNVQMNYTSL
                     ELGEVVATAIRKQTTTLETLNADRVKLLPDPAGGSIESLVVTFAGVTSNNELSSQYSVR
                     GGSYDENIVYVNGLEVFRPLLIRSGQQEGLSFINPDMTEAVNFSAGGFEARYGDKMSSV
                     LDITYKKPKGFEGSASASLLGANAYVGSSSGKFTQVTGFRYKTGRSLLKTTDTDAEYDP
                     NFIDLQTYMTYQLAPKWEINFLGNLAINNYKFIPHTRETSFGTATNAKKFKVFMSGQER
                     DKFETLFGALTLKHNLNDNTELGLQASAFTSKEEEGYDIAGDYWLGDAAEEGGGEIQKL
                     SIARYNEHARNRLHSNIMNVGHYGVARIKNNTLKWGATVQLEKINDKISEWEKRDSAEY
                     SLPQGGGNVNVIANLFSDNKLESTRISGYLQDVFKFRTKQGLFTLVGGVRGSYWSYNRE
                     FIFSPRASIGFIPNFDQNLTFRLASGLYYQSPFYKELRTTVQDEHGNSIIQLNKNLKSQ
                     RSIHVIAGGDYTFRASGRNFKVSADMYYKKLDNLNPYTVDNVKIRYYGENCAQGHAMGL
                     DVKFFGEFVPGTDSWISFSLMKAEQSIRGSEYVPMPNSQGYNVSLFFQDYFPGYKRVKL
                     NLKGVLSGGLPVTAPRTGYEDGYFRTPTYKRVDLGFSYQLAGGTDAIMDRGFFRNLKNI
                     WLGLDIFNLFDIKNTSSYYWITNIDNHQYAIPNYLTGRQLNIRLIVDF"
     CDS             10001..10408
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg20_20"
                     /sec_met_domain="Glyoxalase_4 (E-value: 3.7e-27, bitscore:
                     86.7, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELTHIEHLGIAVKSIEACLPYYEEVLGLKCYNIEEVADQKVKTA
                     FFKVGQTKIELLEPTSEDSTIAKFIEKKGEGIHHIAFAVPDVQAALDEAESKGIKLIDK
                     APRGGAEGLNIAFLHPKSTCSVLTELCMPGK"
     CDS             10521..12074
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg20_21"
                     /sec_met_domain="CT_Btheta (E-value: 6.7e-292, bitscore:
                     960.0, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKVKELIALRETARLGGGEKRIESQHKKGKYTARERIAML
                     LDEGSFEEFDMFVQHRCTNFGIEKTKYLGDGIVTGYGTIDGRLVYIYAQDFTVFGGALS
                     EALAMKICKVMDQAMKMGAPVIGLNDSGGARIQEGVNALAGYAEIFQRNILASGVIPQI
                     SGIFGPCAGGAVYSPALTDFNIMTRGTSYMFLTGPKVVKTVTGEDVTQEQLGGASVHTT
                     KSGVAHFAVDTEEDGLQLIRKLISFLPQNNLEETPLIECKDPIDRLDDNLNDIIPDNPN
                     QAYDMYEVIGTIIDNGEFLEVHADYAKNIIVGFARFNGQTVGIVANQPKVMAGCLDSNA
                     SRKAGRFVRFCDAFNIPLVTLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKVTV
                     TLRKSYGGAYCVMSSKHLRGDMNYAWPTAEIAVMGPSGAVEVIFAKEVAASEDPKACAA
                     EKEAEYKKAFANPYNAAQYGYIDDVIEPRNTRFRIIRALQQLQTKKLSNPAKKHDNLPL
                     "
     CDS             12090..12983
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg20_22"
                     /sec_met_domain="OAD_gamma (E-value: 4.8e-12, bitscore:
                     38.3, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNMINKKIGVLLLFALLVSFGAKAQRATSMRINEVLVINEDNFVD
                     DYGKRHAWIELFNNSAGSVNIAGCYLTNDKSNPKKYPIPKGDVLTVIPPRQHTLFWADG
                     EPDRGTFHVNFTLDPSKENYIALYDADGRTLIDEIVIPASQKADVSYGRTLDGQGEWTA
                     LTKVTPSTNNVTLDSNEKIENFKENDSWGIGMTLTAMAVVFSGLFLLFIIFKQIGKLSI
                     AASKRNAQKAAGAAVIADNAGQESGEIFAAIGAALYEMSDDNHDIEHTVLTIRKVQRSY
                     SPWSSKIYGLREVPKK"
     CDS             13006..13437
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 65.5; E-value:
                     9.6e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg20_23"
                     /sec_met_domain="Biotin_lipoyl (E-value: 8.8e-21, bitscore:
                     65.5, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSFKYTINGNVYKVHISSVVDDIAEVEVNGTPYQVKMEKPAKKQ
                     MVTLKRPAQAPTTASGEPVISRPAASTTKGAVKSPLPGVILQVNCKVGDTVKRGQNLLV
                     LEAMKMENNINADRDGKIIEIKVNKGDSVLEGADLVVIG"
     CDS             13442..14638
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg20_24"
                     /sec_met_domain="OAD_beta (E-value: 6.7e-153, bitscore:
                     500.6, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLGSVLLQAAGTAHESFLQFLGENLELFLTYTGVYNATPGHLIMI
                     LVGLLFIFLAIKYEFEPMLLIPIGFGILIGNIPFKDAGLQVGIYEQGSVLNILYQGVTS
                     GWYPPLIFLGIGAMTDFSALISNPKLMLIGAAAQFGIFGAYIIALQMGFEPNQAGAIGI
                     IGGADGPTAIFLSSKLAPNLMGAIAVSAYSYMALVPIIQPPFMRLLTTQKERLIRMKPP
                     RAVSSTEKIVFPIVGLLLTCFLVPSGLPLLGMLFFGNLLKESGVTRRLAETARGPLIDT
                     ITILLGITVGASTQATQFLTLNSIKIFGLGALSFVIATCAGILFVKFFNLFLKEGNKIN
                     PLIGNSGVSAVPDSARISQNVGLEYDPTNYLLMHAMGPNVAGVIGSAVAAGILLGFLG"
     CDS             14742..14996
                     /locus_tag="ctg20_25"
                     /transl_table=11
                     /translation="MRTTIHQKYINGCIIKNYLRHSLPFYIRPYQIFCSTVIGSVSGFA
                     SCSNVVPKNNQIINRIIAITTPKTSSTFVFFRLMSILQY"
     CDS             complement(15259..17367)
                     /locus_tag="ctg20_26"
                     /transl_table=11
                     /translation="MQITYYRHKKGVLRMHSRDMEYIVGLLKNGKDAEAILSVRRKLNM
                     AFLARTTDLSGKLPVLAFGSTFKKNGDGIQLRRYNGYVLLEVNGLESQNEAEAVRREAA
                     ALPQTLLAFVGLSGRSVKIVVPFVLPDGSLPKKEEQARMFHAAAYQLAVRHYQPQLGSI
                     ISLKEPFLSRGCRMSVDPDAYYNPDAVAIRIEQPLQMPDGGDLKIVPSPVRDPLEMMAP
                     GADRNGQIATLFSVILMEMTRRFSESPEDDIQLLFIDLAQACCRLGIPEEEAVGWTLRY
                     EALKKYKIDVRMAFRTAYTLENVSNRAEPLSSVPPSMSLVLRLDEFMNRRYFFRTNEMS
                     GGVEYLDRSMIQFVYKPYTTKVRNSICLEAQQEGLNVWDKDIDRYVNSDRVPIYHPIDH
                     FLGNLPAWDGKERIRALAGRVPCDNPIWGDLFYRWFLSMVAHWMELDSEHGNSTTPLLV
                     GGQGCGKSTFCLNLLPPVLRPYYTDSIDFGNRRGAELALHRYVLINIDEFDSVKSSHQS
                     FLKHILQKAVVNTRLPYQSASRNLRRYATFIATSNNYDLLTDPTGSRRFICVEVKGRID
                     YAQPIDYAQPIDYDQLYAEAKELLRRGERFWFTPEEEALITENNRDFQQQPAEEQLFLR
                     YFKIAEDIEEAKPLLASEILDMIAEKQPGFNITKTMILNFGKLLKRNSVPNKRTMRGTC
                     YYVEEVDG"
     CDS             complement(17367..17753)
                     /locus_tag="ctg20_27"
                     /transl_table=11
                     /translation="MAHYYVVRQKLDKTGAEDKVRYYGVPVTCGRVSTKKLADLVADRC
                     SLSRGDVFASVCEIGGMILELLKDGYSVELDGLGDFYLSAGSEGFEDPKKCTPHRVKAR
                     RVCFRMAPCVRKSMKFVKFERNPW"
     CDS             complement(18356..19018)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M22"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg20_28"
                     /sec_met_domain="Peptidase_M22 (E-value: 3.4e-24, bitscore:
                     77.8, seeds: 111, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDGEVLFAKASFDGPSHAALLGVFVEEALSVLKKKGKKALDAVAV
                     SSGPGSYTGLRIGVSVAKGLCFGFGIPLIGIHTLDIMAATVNSKGDSQIVSITDDCLYC
                     AMLDARRMEVYAAIYDASLKPVRETRADIVEVGTYASYLEKGKVCFFGNGASKCKSVIT
                     SPNAIFIEDIHPLAVNMIPLSEQAFAAGKFEDTAYFEPFYLKEFQATVAKNKVLLAR"
     CDS             19311..20171
                     /locus_tag="ctg20_29"
                     /transl_table=11
                     /translation="MTGFGKVTAELPSKKVTVEIKALNSKQLDLSTRIPSIYKEKEMQI
                     RSLLLQSLERGKVEFNIFVEYIGKDTPTQINLAAVENYYNQIKDIADRLNIGLPADWFQ
                     TLLRMPDVIKTEAQEVNEEEWNVVEKAIKEAIGHLCDFRIQEGAMLQKLFEQKIANISR
                     LLSEVEQYEKERIEKIKARIMDNLEKIAGQDYDKNRFEQEMIYYIEKLDVNEEKNRLDN
                     HLKYYISTMESGHGQGKKLGFIAQEMGREINTLGSKSNHAEMQKLVVQMKDELEQIKEQ
                     VLNVL"
     CDS             20181..20750
                     /locus_tag="ctg20_30"
                     /transl_table=11
                     /translation="MAGKLIIFSAPSGSGKSTIINFLLKQNLNLHFSISATSRAPRGTE
                     KDGVEYYFLTPDEFRARIAAGDFLEYEEVYTDKYYGTLKSEVERRLMSGDNVIFDVDVV
                     GGCNIKKFYGDRALSVFIQPPSIEDLRSRLEGRGTDAPEVIESRIAKAEFELGFADKFD
                     VIVVNDKLEVAEKEALKVIKEFLKKA"
     CDS             20747..20920
                     /locus_tag="ctg20_31"
                     /transl_table=11
                     /translation="MNGKKLSKKWLYTFIGIAFVALATCTAALYYKEYIIATGTGLVFG
                     AQVINIIKWKRD"
     CDS             20905..21516
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CTP_transf_like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg20_32"
                     /sec_met_domain="CTP_transf_like (E-value: 9.6e-25,
                     bitscore: 79.4, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VETGLKENTASKRKTGIYSGSFNPVHIGHLALANWLCEFTELDEL
                     WFLITPHNPLKEKEELMDDRLRYELVKKSIAGYPKFHASDFEFSLLQPTYTINTLRTLE
                     ASYPDREFYFIMGADNWKYITRWVEYEAIISNYPIFIYPRKGFDVEIPAQYPHIKKVDA
                     PLVEISSTFIREAFKTGKDVRFFLPEAIRNLPFPLQNNTF"
     CDS             21607..23337
                     /locus_tag="ctg20_33"
                     /transl_table=11
                     /translation="MNLLELSEQEIIRRNSMEQLRQMGIEPYPAAEYVTNAFSKEIKEN
                     FKDDAEPRPVSIAGRIMSRRIMGKASFMELQDSEGRIQVYISRDDICPEENKDLYNIVF
                     KKLLDIGDFVGIKGFVFRTQMGEISVHAQEITVLSKSLKPLPVVKYKDGVAYDGFNDPE
                     LRYRQRYVDLVVNDGVKDIFMKRAAVIKTMRTALDEAGYTEVETPILQSIPGGASARPF
                     ITHHNSLDIDLYLRIATELYLKRLIVGGFEGVYEIGKNFRNEGMDRTHNPEFTCMELYV
                     QYKDYNWMMSFTEQLLERICIAVNGTCESVVDGKTINFKAPYRRLPILDAIKEKTGYDL
                     NGKSEDEIRTICKDLNLEIDETMGKGKLIDEIFGEFCEGTFIQPTFIIDYPVEMSPLTK
                     MHRSKPGLTERFELMINGKEVANAYSELNDPIDQEERFKEQLRLSEKGDDEAMFIDQDF
                     LRALQFGMPPTSGIGIGIDRLVMLMTGQTTIQEVLLFPQMRPEKTVKKDTADKYVALGI
                     DEAWVPALHKAGYLTTDTLVDANPNKLRQELCEMNKKYKLELQNPTAEEVEAWIAGAAK
                     "
     CDS             23348..24343
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_Gly3P_dh_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg20_34"
                     /sec_met_domain="NAD_Gly3P_dh_N (E-value: 3.5e-33,
                     bitscore: 106.7, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLPGKIAIMGGGSWATALAKIVLSTQDSINWYMRRPDQVEEFLL
                     LGHNPSYLSAVKFDTDKIKFYTDINKVIKDSDTLIFATPSPFLKQHLMKVTTSMQDKFI
                     ISAIKGIVPDENMLVADYFAEYYNVPIDNIAVIGGPCHAEEIALERLSYITLACPNIEN
                     ARAFSSVFKNQYLNNSCCKDVTGIEYASVLKNVYAIVAGICHGMKYGDNFLAVFICNAI
                     EEMRNFLNAVHGLERDVTDSVYLGDLLVTAYSRFSRNRTFGTMIGKGYSVKIAQLEMEM
                     IAEGYYGTKCIREINEKYKVNMPILDTLYSILYEKKSPTTAIRQLTETFK"
ORIGIN
        1 tgccggccat gccccctctt tcgtacagac ataagcagct gtgcggacgg caaattcatg
       61 cgcttccctt agcgaagccc cttccagcaa cgaaatgacc aatgctccgg agaaagcatc
      121 acctgctcca accgtatccg ccacctgcac ttccggggtt tgcaaagtcg attcttcatt
      181 agcggtatat atcgtactat aagctcctcc ggccgtcaga accaccaagc ggagattata
      241 gtgttctata aaccaatgag ccacctcctt gtccgttcct tccaaatgaa acatatcccg
      301 caggacgacc aactccccgt cattcacctt caacatattt gctagataaa gcgactcttc
      361 gatcaactct ttcgtataat aatgctgacg caaattgatg tcaaaacaac gataagcatc
      421 gtccggggca aaagaaagaa tcgcttgtat cgtctctctt gactgtgcgg aacgctgtcc
      481 taacgtaccg aagcaaatgg catccgcccg ttcggccaaa tcaatcgcat ttgacgtcgg
      541 agaaagatga tcccaagcta cacgttcatt aataatatag tcagggacac catcctgcag
      601 agtaacctgt accgttccgg tcggataagg gactttctcg atcagatacc ggatcgaatt
      661 attatccagt tcttcgagga tttcgcgccc cagcccatcg tctcccacgg cgctgatagc
      721 atatccttcc gcccccaacc gcgacgcatg gtagacaaaa ttgataggag caccacctgc
      781 tttctttcct gttggcaaca tgtcccacag gagttctcct atgcctacta cgaccggttt
      841 cttattgttg ctttgcattg tttcattata gtttatttga caaggataat ttattatcta
      901 cgatgcaaag atagagacag gtagcagatg cgacgataac taatgctaca agattgataa
      961 cacttgttac attatactct tattttcgag ttacatgcac aaatgttaca caaatgtaac
     1021 gagcgttatc aaagagaaga atattattcc ttttccagat actccgtcgg agtaatattg
     1081 taaacggctt taaaacattt cgagaaataa gcaggcgaac cgaagcccgt cgcataagcc
     1141 acctcattca cattcccggc tttccgtcga agtagagcag cagctttctt caaacgatag
     1201 ttacgcagga aatcggtcgg tgtcactccg gcaagctcct tcaccttccg gtaaagatgc
     1261 acacgcgaca agcccaattt ttcactacct ttctcaatac tgaaatccgg atcggcatag
     1321 gactcttcga tcagtttcaa gaaacgattc ataaaaagat cgtccatgct tcccgctttt
     1381 tcctccttca cggaaacagc aggcgaagaa gcatcgcgag cataagcctc acgcaaccgg
     1441 acacgatcct ccagcagctt gatgatacgc agtttcacga cttctatgtt aaaaggtttc
     1501 tggatatacg cgtccgcacc actggcagcc ccgtacatct gctgtttgtc gtcggacaaa
     1561 gcagtcaaca gcataaccgg aagatggctc aggacaatat ccgacttgat cttacgacaa
     1621 agatcgaaac cgttcatttc cggcatcatc acatcgctga taaccatcga gatatcttcg
     1681 ttcatcagta cctccaaagc cttcacgccg ttatcggcaa ccaacacacg gaagttctgt
     1741 tttaattccg cctgcaagta actctgtata tcaagatcat cttctacgac cagaacagta
     1801 taattgtagg tacggttcaa aacctcctgc aattcatccg tgttcaagtc ggcgacacca
     1861 ctggaaagct cggttacgga aagatcgaat atacaagatt cgtcaaaatg agatttacct
     1921 ttcaagagga tgaccgtaaa gacagtactc ttatgcggaa cactctccac ccggatcgtg
     1981 cctttgtgca tgtggacgaa ctcacgcgtc aagtgcagac cgatccccgt ccccgtcaca
     2041 tagttctggt caccggtaaa gaaacggtca aagacggaag caatattttc cgacggaatg
     2101 cctttgccat tatcttcgac agaaagctcg acctgatctc ctttatcctt caggcggatc
     2161 gtgaccgtac ctccgtccag cgtgaacttg aatgcattgg acaaaagatt ggccagaatc
     2221 ttctccatct tatccctgtc tacccatata ttaacagaag ggcagtcatg ctcaaacgtg
     2281 aaatgtatct gcttggtggc agccatcgta tcgaaataag atttcacttc tgccacaaaa
     2341 gcaactaaat ctacctctcc gacccgcata ttcatcttat tgctctctac ctttcgaaaa
     2401 tcaagtaact ggtccacgac tctcttcaac ctttccgcat ttttccgaat gatacggata
     2461 tcgtctgcca atgaagaacc ttccggagcc tctttcgaca gcttgccgag cggaccgagg
     2521 atcaacgtca acggcgtctt gatctcgtgt gtgatattgg taaagaattg cagtttctga
     2581 gccgtcgact tctcaatata acggtttgcc tcagccaatt cttctttttg ctgttgtacc
     2641 tgcaagttcg tacgtttcag ctcgcggttc ttccgcttca ccgcccggtt cacatggatc
     2701 acgtacaagg cggacaaaag caacatcccc atcagcaaaa ggataatgcc gacggagttt
     2761 tggaggaacg tgtatttgga aagcatactc tccaaattct cccgttgcaa ctcgatctgg
     2821 tgctgatagt cgaccacctg ttcagactgg ataaacagcg ttccggcatt gttcttatcg
     2881 atcaaggcag aagagagcaa atattgccga gacacatctt ctccgttcaa tatctgcatg
     2941 gctacacgga tagcaaggct cccacccgtc ggatacaaga ccgaagcggc caactctccg
     3001 tgcatgacgg cttccagccc cgatccccgt cccgaaacgg catcgatccc cacaaaacaa
     3061 atcctgtccg ccaatccggg atgcatcctt tcgattgccc tgcgggcagc cattgccatc
     3121 acatcattat gtgcaaacac aacatccacc tcctccagca aatccatttc cgctatctcc
     3181 ttctccaccg tttccggctt ccatttccca aatatttcct tcaccttgat gcgggagttc
     3241 aaaacctcca taaaaccgcg atggcgatcc tgcgccggag aagaaccgga caagccccat
     3301 acttccaata cggtaggata tttctctttc acctgtcggt tcacgaaaaa gccggcctgg
     3361 cgaccgatct cgtaattgtt accaccgata taagtcgtat attcgtccga actgatcttc
     3421 cggtctacca ggatagtcgg aatgccggca cggtaggcct caatcgcaat aggagtgaca
     3481 ggttccgatt cattggcgga gataatcaat agatcgacct tacgttttat caggctgcgt
     3541 atctgctcca cctgcaacaa actactgtcc gctgcatcct cgactaacag ggagacgccc
     3601 ggatattcgg aggcctgcac cttcatatcc agcaacatcg atttacgcca agaaccttca
     3661 agcgtacact gcgagacgcc gataacaaac tttttcttct ccgaatctgt tttgcaggaa
     3721 aagcaggatg ccagaagtaa gaccagcaga gcgtaataag ttagagcagg tttcattctg
     3781 ttttatttac aggtttctgc aaatgtacgg agaaatggca taccagccaa tatttatttt
     3841 gtacattcgt cctccagtaa tcaattattc gcatgaagat cataaacgaa gctttattgg
     3901 atgaaacgac cgggcgtgcc aaacagtcgc ctcggctacg catgaactac aattttcatg
     3961 agcatttgga cgatcccgtc aaccgtttgc tcaatgccct ggaaccggga acctacctcc
     4021 gcccacaccg ccatctgaac cctaaaaaag atgaaatatt cctcctgctg cgcggtcgca
     4081 ttgctgtatt cctctttgac aacaaagggg aaatcaccca aacacagata ctcgatccga
     4141 aagaaggtgt ttacggcgcc gaaataaagg cgggaacatg gcacgggctg ttagttctag
     4201 aatccggctc tgtcatatat gaaatcaagg aagggccgtt cgctccgctc gctccggaaa
     4261 atttcgcacc ctggagtccg gctccagaag acacgaaagg ggtggcaaaa tatatggagt
     4321 tattaggaaa ggctatataa ccttgcacta ccttcccgtt ccccttaaag aaaactttat
     4381 tttcataggg atgaaacttc tttttcatcc ccatgaaact atcattccat ccctatgaaa
     4441 ctgttatcac atacctatcg gctcctttat tgctggaata cttttgtcaa acggatcatg
     4501 gcttctttca ccggacagtc attcttatcc gtcctgacaa tagcgttctc ataattttca
     4561 actttcaaat accaacatct gacaatgctt gcagtcgaac tgcaaccgga ggcgcgtatc
     4621 tttataaagc agataatacg gttccttgta gggagacttg tctttctgat aagtaggaca
     4681 ccaccccatg ctgtagcgca ggcagtgttt ggtaaacatc aacggaacat ctttccgggg
     4741 agacagttca aatgccgggt cgatctgttc caccccgtga tcctggtaga acgaacgggc
     4801 tttcccgttg gcaacattcc ccaaataagt aagttggcgt tcggggaaag gtatcgacac
     4861 ggacggctgc acacgtttca ctgtctcacg aggatagcgg gcacggcgtg cttccagcaa
     4921 cttctccact cctctacggc gcatatcggc aagcagagaa gagggaacga accagttttc
     4981 aaacaaaccg accaccacct tcgatgcctc gaaaggcgta ttccccaacc tggatagctg
     5041 tgtccgtata ttatcctgct gttcacgacg cgccagctct tttgcaaacg gctcggtcag
     5101 catgatccgt gctcccgtct catcctccat acaaagcgta aaaccgaagg gattgtccaa
     5161 gaactcgatc tccacggaca gcttacgttc ggctgaaggc ttggcgagca gtttatcaaa
     5221 cgcctggtcg aaattgcggt aaagaggagt cttgggggca agctgcggca tatccagcgg
     5281 aaacacccgg tttgcctcca cccggtttac acgaaaacct tccaattcgc ctttcctatt
     5341 gaagaaaaca agcccgtctc cgttgttcaa ttgctttaag ccggccacgg taaaggaatt
     5401 acctttgatc tccttgactg ttccgacagg ttcgcccaac gacttaggtg tattaaaagc
     5461 ggtaatatcc gccgtccgtc cctccaaaag gaacggggtg agcccacggt taaaactctt
     5521 ttcagctacc ggctcgaacg tataagtgct tcgtccagca gaagcacgac gatattccgg
     5581 acggcgggac aggactgcat ctaacttctt ccgataataa gccgtgatat tcttgacata
     5641 gccggcatct ttcaaccgcc cttcgatctt gagggaagaa acacctgcat ccaacagggc
     5701 ttccagctgg tcggagcggt tcatgtcctt gagcgaaagc aagtgtttat gggtgacgat
     5761 ctccgtccct gtcgcatcaa ccatcgtata gggcaggcgg caatattggg cgcattctcc
     5821 gcggttagca ctacgtccac tcaaagcggc gctcagataa cattgcccgc tatagctgac
     5881 acagagggcg ccgtgcacga atacttccag cggaacggta gtcgcttccg atatccggcg
     5941 aatctcgttc agcgacaatt cacgtgccag aaccacctgt gtaaagcctg cggcttcgag
     6001 gaaacggacc ttttccggtg tgcggttgtc cgtctgcgtg ctggcgtgaa gcggaatagg
     6061 aggcaggttc agccgggtaa tccccatatc ctgaatgatc agggcatccg tcccgacacg
     6121 ccagagatcc cagatcatcc gttcggcttc ttccaactca tcttctttca ggatcgtgtt
     6181 gagcgtaaca tagatacggg cttcatacag atgcgcatac tcgcaaagct cacgtatatc
     6241 ttccaaagag ttgccggcag cagaacgcgc accgaacttg ggcgcaccga tatagacggc
     6301 atcggcaccg tgattaatcg cttcaatccc gcaattgagg tctttagccg gagagagaag
     6361 ttctatagga cgggattttg tttgcatgct attatttctt atttcttgat tacaaatcac
     6421 ccaacttgct gatatcctcg atacggaacg gggtttcctg atagacataa tagttcagcc
     6481 agttggtgaa cagaagattg gcatgaccac gccagcggac caccggaccg agggccggat
     6541 tgttattacg gtaatagtta cggggaacgg caattggcaa tcccttgttc acgtcgcgca
     6601 tatactcgtc attcagcgtg taaggcgagt attcggaatg cccggtgata aaaaactcgc
     6661 gtcctccgcg cgccatcgcc atatagacac cagactcttc gctttcggac aagagcgtca
     6721 aatcgggaac tttcatcaca tcctcgcggc gtatctccgt atgccggctg tgcggcacat
     6781 agaactcgtc gtcgaagcct cggaagatcg gcacataggg ctcgcgcaac gtatggcgga
     6841 acacgccgaa catcttggct ggcagatcat atttggggac accataaaaa tggtacaacc
     6901 cggcttgcgc cgcccagcat atatataagg tagaagtcac atgcgtacgc gcccaatcga
     6961 atatctcggt cacttcctcc caatagttca cttcctcgaa aggcatctgc tctaccggag
     7021 cacctgtgat aatcatgccg tcgtaaaaat catcctgcat ctcgtcaaag tctttataga
     7081 attccttcat atgctcgatc ggcgtgttct tgggagtatg gccttttatc ttcataaagt
     7141 cgagctccac ttgcaagggg gtattgctca ggaggcgaac aaggtccgtc tccgtcgtga
     7201 tcttcagtgg catcaagttc agcacaacta cacgtagcgg acgaatgtcc tgctcagacg
     7261 cacgcaacga gtccatcaca aagatgtgct ctttcttcaa cagctcaaca gctggcaagt
     7321 tcttctgtag gtttaaaggc atcttctttc cttaattatt tatataaggc acaaagatag
     7381 tgagaaattg cctttcattg aaaataaatc gttgtttccc gcgtttgtag atttaataat
     7441 tagatggaat atgaagattc gtgcaatagc tacactacta tttatattat tttcgataag
     7501 tgctttcggg cagggacgtg ccaaaatcag cggttatatc cgcgacgcgg acggtaatcc
     7561 gctggacttg gtcaatatcc gggtcaagaa cacgttaaac gggacgatga gtaatgaaaa
     7621 aggccactac tcgctttcgg tcgctaccgg tgactcggtg acgcttatct attcatgcct
     7681 gggctacaac aaggccgaaa ggatcctacc tcaggtaacc aaagatatgc gtctcaacgt
     7741 gcagatgaac tatacatcac tcgaactggg agaagtcgta gctaccgcca tccgaaagca
     7801 gacaaccacc cttgaaaccc tgaatgccga ccgcgtcaaa ctactccccg accctgccgg
     7861 aggaagcatt gaaagtctgg tcgttacatt tgctggcgtt acttccaata acgaattaag
     7921 ttcgcaatac tccgtacgcg gcggcagcta tgacgaaaac atcgtatatg tgaacggact
     7981 ggaagtgttc cgtccgctgc tcatccgttc cggacaacag gaagggttga gttttatcaa
     8041 cccggacatg acggaagccg tcaatttctc cgccggagga ttcgaagccc gttatgggga
     8101 caagatgagt tccgtgctgg acatcaccta caaaaaaccg aaaggattcg aaggttcggc
     8161 ttccgccagc ctgctgggag ccaatgctta tgtgggcagt tcttccggca agttcacaca
     8221 ggtgaccggt ttccgttaca aaacaggacg atctcttttg aaaacaaccg atacggatgc
     8281 cgaatatgat cctaatttca ttgatttgca gacttatatg acataccagc ttgcccccaa
     8341 atgggagatc aactttctcg gaaacttagc cataaacaat tataagttca ttccccacac
     8401 ccgagagact tcttttggaa cggcaacaaa tgccaaaaaa tttaaagtat tcatgagtgg
     8461 ccaggaacgg gataagttcg aaacgttatt cggagcactc actttaaagc ataacctgaa
     8521 cgacaatacg gaactcggct tgcaagcatc cgcctttacc agtaaggaag aggaaggata
     8581 tgatattgcc ggtgattact ggctgggaga tgcagccgaa gaaggaggcg gagaaataca
     8641 gaaattatcc atcgcacgct ataacgagca cgctcgcaac cgtctgcact ccaatatcat
     8701 gaatgtcggg cattatggtg tcgctcgcat aaaaaacaat acgttgaaat ggggtgctac
     8761 cgtccagttg gagaaaatca acgacaagat cagcgaatgg gaaaaacgcg actccgccga
     8821 atactcgtta ccgcaagggg gcgggaatgt caacgtgatc gcaaacctgt tctcggataa
     8881 caaactggaa agcacacgta tttccggcta tttgcaggat gtattcaagt ttcgtaccaa
     8941 acaaggactg ttcacgctgg ttggtggtgt acgcggcagc tattggagtt ataacaggga
     9001 atttatattc agcccgcgtg cttcaatagg tttcattccg aacttcgacc agaacctgac
     9061 atttcggctg gcttccggtc tgtattatca gtctccgttc tataaggaat tacgtacaac
     9121 tgtgcaggac gaacacggca acagtatcat acaactgaac aaaaacctga aatcacagcg
     9181 ttccatccat gtcattgcag gaggcgatta tacattccgg gcatccggca gaaatttcaa
     9241 agtcagtgcc gatatgtatt ataaaaaatt ggataacctg aacccctata cggtggataa
     9301 tgtcaaaatc cgatactacg gcgagaactg tgcgcaaggc catgcgatgg ggctcgatgt
     9361 caaattcttc ggcgaatttg ttccgggtac ggactcctgg atcagcttct ccctaatgaa
     9421 agcggagcaa agcatccgag ggagcgaata tgtaccgatg cctaacagcc aaggttataa
     9481 tgtctcgctc ttttttcagg attatttccc cggatacaaa cgtgtcaaac tgaatctgaa
     9541 aggcgtactg tccggcggcc ttcccgtcac agccccacgt acaggctacg aggacggcta
     9601 tttccgtact ccgacctaca aacgcgtgga cctcggtttc tcctaccagc ttgccggggg
     9661 aacggatgca atcatggatc gcggattctt ccgcaatctc aagaacattt ggctcggatt
     9721 ggatattttc aacttgttcg acataaagaa cactagttcc tattattgga ttaccaatat
     9781 agacaaccac cagtacgcaa tccctaatta cctgaccgga agacaattga atattcgact
     9841 tatcgttgat ttttaaccac atgatttcaa aaatatgctt tttaaacata tccggatcat
     9901 gctgataaat attaacgaat tatttctcta ttaataaaaa gagtgtacct ttgccaacat
     9961 agaacaaaaa gcaatattaa attactaaat tattattgac atggaactta cacatatcga
    10021 acatttgggt atcgcagtaa agagcatcga agcttgcctg ccgtattatg aagaagtttt
    10081 aggactaaaa tgctacaaca tcgaagaagt agcagaccag aaagtaaaaa ctgcattctt
    10141 taaagtaggc cagactaaga tcgagttgct ggagccgaca agtgaagaca gtacaatcgc
    10201 taaatttatc gaaaagaaag gtgaaggtat ccaccacatt gcatttgctg ttcccgacgt
    10261 acaggcagca ttggacgaag ccgaatcaaa aggtatcaag ctgatcgaca aagctcctcg
    10321 tggaggtgca gaaggcttga acattgcatt ccttcacccg aaatcgacat gcagcgttct
    10381 gaccgaactt tgcatgccgg gaaaataaga aacaattgac aattgagaat tgacaattat
    10441 ttgatgctat tcaattgtca attctcaatc gttaattgcc aattaaataa gttcatttct
    10501 aacaacaaat ctatagtaca atgagtaacc aacttgaaaa agtaaaggag cttatcgccc
    10561 ttcgcgaaac agctcgttta ggtggtggag aaaaaagaat cgaatctcag cacaaaaaag
    10621 gtaaatacac cgcacgcgaa cgtattgcca tgttgctgga tgagggaagt tttgaagaat
    10681 tcgatatgtt cgtacaacat cgttgtacaa acttcggtat tgaaaaaact aagtatttgg
    10741 gcgacggtat cgtaacaggt tacggaacga tcgacggacg tctggtatat atttatgctc
    10801 aggatttcac cgtgttcggc ggtgctttat ccgaagcatt ggccatgaag atctgtaaag
    10861 taatggatca ggccatgaag atgggtgctc ccgttatcgg tctgaacgac tcgggtggcg
    10921 cacgtatcca ggaaggtgtc aacgccttgg ccggttatgc agaaatcttc caacgtaata
    10981 tcttggcttc cggggttatt cctcagattt ccggtatctt cggtccatgt gccggcggtg
    11041 cggtttactc tcctgccctg acagacttca atatcatgac ccgcggaaca agttacatgt
    11101 tcctgactgg tccgaaagtt gtaaaaacag ttacaggcga agacgttaca caggaacaat
    11161 taggtggcgc aagcgtacat acgaccaaat ccggtgtggc ccacttcgca gtcgatacgg
    11221 aagaagacgg tttacagttg atccgcaaat tgatcagctt cctgccgcag aacaacctgg
    11281 aagaaactcc tctgatcgaa tgtaaagacc cgatcgaccg tctggatgac aacctgaacg
    11341 acatcatccc tgacaatcct aaccaggctt acgatatgta tgaagttatc ggaaccatca
    11401 tcgataacgg cgaatttctg gaagtacatg ccgactatgc caagaacatt atcgtcggtt
    11461 tcgcccgttt taacggccag actgtcggta tcgtagccaa ccagccgaaa gtaatggcag
    11521 gctgtctgga cagcaacgcc tcccgcaagg caggccgttt cgtccgtttc tgcgatgctt
    11581 tcaacattcc tttggttaca ttggttgacg taccgggatt cttaccgggt acaggccagg
    11641 aatacaacgg tgttatcctg cacggagcca aattgcttta cgcttacggc gaagccacag
    11701 tgcctaaagt aactgtaaca ttgcgtaaat cttacggtgg agcctattgt gtgatgagct
    11761 ccaaacatct gcgtggcgat atgaactacg catggccgac agccgaaatc gcagttatgg
    11821 gcccaagcgg cgctgtagaa gtgatctttg caaaagaagt ggctgcctcg gaagatccga
    11881 aagcttgcgc tgcagaaaaa gaagccgaat acaaaaaagc atttgcaaac ccatacaatg
    11941 cagctcaata tggctatatc gacgatgtta tcgaacctcg taacactcgt ttccgtatta
    12001 ttcgtgcttt acaacaattg cagaccaaga agttaagcaa tcctgccaag aaacatgaca
    12061 atctgcctct ataattctta aaacaggaaa tgaatatgat taataagaaa ataggggtat
    12121 tgctgctgtt cgcgttgctc gtttcattcg gggcaaaagc acagcgtgca acctccatgc
    12181 gaataaatga agtgctggtc atcaacgaag ataactttgt tgatgattac ggcaaacgcc
    12241 atgcctggat cgaattgttc aacaattcgg ccggttcggt caatatcgcc ggttgctact
    12301 tgactaatga caagagcaac ccgaaaaagt atccgattcc gaagggcgac gttctaacag
    12361 taattcctcc tcgccagcac actttgttct gggcagacgg agaaccggat cggggaacat
    12421 tccatgtcaa tttcacgctc gacccatcaa aagaaaatta cattgcgtta tacgatgcag
    12481 acggtagaac tctgatcgat gagatcgtta tccctgcttc acaaaaagca gatgtcagct
    12541 atggtagaac tttagacgga caaggtgaat ggactgctct gacaaaagtt acacccagca
    12601 ccaataacgt aacattggat tctaacgaga aaatcgagaa ctttaaagaa aatgattctt
    12661 ggggtatcgg tatgaccctg actgccatgg cagttgtgtt ctccggatta ttcctgttgt
    12721 tcatcatctt taaacaaatc ggaaagctct cgatcgcggc cagcaaacgc aatgcacaga
    12781 aagcggccgg agcggctgtt attgcagaca atgcaggtca ggaatccggg gaaatctttg
    12841 cggctatcgg tgcggctcta tacgaaatga gcgacgacaa ccacgacatc gaacatacgg
    12901 ttctgacgat ccgcaaggtt caaagatctt attctccgtg gagttccaag atttacggtc
    12961 tgcgtgaagt tcccaaaaag taattatctc taaaaacaaa caagaatgaa aagttttaaa
    13021 tatactatta acggtaacgt atataaagta catatcagct cggtagtgga tgacatcgct
    13081 gaagtagaag taaacggtac tccctatcaa gtaaaaatgg agaaaccggc aaaaaaacag
    13141 atggttacac tgaaacgccc ggctcaagct cctacaacgg caagtggcga accggttatt
    13201 tcccgtccgg cagcctcaac caccaagggc gctgtcaaat ctccgctgcc aggtgtaatc
    13261 ctgcaggtta actgtaaagt cggtgatact gtcaagagag gccagaatct acttgtcctc
    13321 gaagccatga agatggaaaa caacatcaat gccgaccgtg acggcaaaat cattgaaata
    13381 aaagtaaaca aaggggattc cgtactggaa ggtgctgacc tcgtcgtaat aggataatat
    13441 tatgttagga tcagtattat tacaggcagc gggtacggct catgaaagct ttctccagtt
    13501 cttgggagaa aacttggagt tgttcctcac ttatacagga gtctacaacg cgacaccggg
    13561 tcaccttatc atgatccttg tcggtctgtt gttcatcttc ctggctatta aatatgaatt
    13621 cgagcctatg ctccttatcc ctatcggatt cggtatcctg atcggtaaca ttccgttcaa
    13681 agatgcagga ttgcaggtgg gtatttacga acaaggttct gtgctgaaca tcctctacca
    13741 gggtgtaacc tccggatggt atccgccgtt gatcttcctc ggtatcgggg ccatgaccga
    13801 tttctccgca ttgatctcca atcctaaact gatgttgatc ggtgcagcgg ctcagttcgg
    13861 tattttcgga gcatatatca tcgctcttca aatgggattt gaaccgaacc aggccggtgc
    13921 aatcggtatc atcggtggtg ccgacggccc gacagcaatc ttcctttctt ccaagttagc
    13981 tccgaacttg atgggtgcta ttgcagtatc agcatactct tatatggcgc tggttcctat
    14041 tatccagcct ccgttcatgc gcctgctgac gactcagaaa gaacgtctga tccgcatgaa
    14101 accgccgaga gccgtttctt ccacggaaaa gatcgtattc ccgatcgtag gcttgttgct
    14161 gacttgcttc ctagttcctt ccggtctgcc tctgttgggt atgctgttct tcggaaattt
    14221 gttgaaagaa agtggtgtaa cacgtcgttt ggctgaaaca gcccgtggtc cgctgattga
    14281 tacgatcacg atcctgttag gtattacggt aggtgcttct actcaagcaa cccagttcct
    14341 gacattgaac tccatcaaga tcttcggttt gggagcgttg tcattcgtga tcgcaacttg
    14401 tgcaggtatc ctgttcgtga agttcttcaa cctgttcttg aaagaaggca ataagatcaa
    14461 tccgcttatc ggtaactccg gtgtgtctgc cgtgcccgac tctgcccgta tctctcagaa
    14521 cgtaggtctg gaatatgatc cgaccaacta cctgttgatg cacgccatgg gtccgaacgt
    14581 agcaggtgta atcggttctg ccgtagcagc cggtatcctg ttgggattct taggataatt
    14641 cacttattct acataaaaag gagctgaact ccaagtcatc tccaaatata caaacttacc
    14701 caagtttacg gactttaacg tattcttggg taagtttgta tatgcgcaca acgattcatc
    14761 agaagtacat taatggctgc atcataaaaa actatttacg acacagcctc cctttttata
    14821 tccgacctta tcagatattt tgttcgacgg tcatcggatc tgtctctgga tttgcctcct
    14881 gttccaatgt tgtccccaaa aacaaccaaa tcattaacag gataatcgcg atcaccacac
    14941 caaagaccag cagtacattc gtattctttc gtctcatgtc cattcttcaa tattgatttg
    15001 aagattaaac aagacacccc cttttttggt ttaaccgttc cttacttttg ttctttattt
    15061 aactgagtaa atattttaga aagaatgttt ttttcttcac ttacaaatac agttggaaat
    15121 agacgatcca actatcatac catcataatt ggaaataacc cactatatat caacacaaaa
    15181 cagccatgac agttcgcaaa acaactgtca tggctactat cataccatca tacataaaat
    15241 tagtcaatca attatatatc aaccatctac ctcttccaca taataacaag tccccctcat
    15301 cgtccgctta ttcggcacgc tattccgctt caaaagcttg ccgaaattaa ggatcatcgt
    15361 ttttgtaatg ttaaaaccag gttgtttctc cgcgatcata tccagtatct cggacgccag
    15421 aagcggcttt gcctcttcaa tatcctccgc gatcttgaaa taacgcagga acagttgctc
    15481 ttcagccggc tgctgctgga aatccctgtt gttttcagtg atcagcgcct cttcctccgg
    15541 agtaaaccaa aaacgttcac cacgcctcaa taattctttc gcttccgcat acaactgatc
    15601 ataatcgatc ggctgggcat aatcgatcgg ctgggcataa tcgatccggc ccttcacctc
    15661 cacgcaaatg aaacggcggc taccggtcgg atccgtcagc aaatcataat tgttgctggt
    15721 cgcgataaac gtggcatagc gacgcaagtt acggctcgcg ctctgataag gcaaacgggt
    15781 gttcacaacc gctttttgca ggatatgctt caaaaaactt tgatgagaac ttttcactga
    15841 atcaaattca tcgatattaa tcaacacata ccggtgcaaa gccaactccg ccccacggcg
    15901 attgccgaaa tcgatactgt ccgtataata aggacgcaac actggtggca acaaattcaa
    15961 gcaaaacgtg gacttcccac acccttggcc accgaccaac agaggtgtcg tactattccc
    16021 gtgttccgaa tccagttcca tccaatgtgc caccatgctt aggaaccagc ggtaaaacaa
    16081 atctccccat atcggattgt cacaagggac acgcccggct aatgccctga tgcgttcttt
    16141 tccgtcccaa gccggaagat tcccaagaaa atgatcgata ggatgatata tcggaacacg
    16201 atcggaattg acataccggt cgatatcctt gtcccataca ttcaaccctt cctgctgggc
    16261 ttccaggcaa atggaattcc gaactttcgt cgtataaggc ttgtaaacga actgtatcat
    16321 cgaacggtcc aaatattcca ctccaccgct catctcattc gtccggaaga aataacgccg
    16381 gttcataaac tcgtccaacc gcaacaccaa cgacatggat ggcgggacgg aagagagcgg
    16441 ctccgcccgg tttgaaacat tctccaacgt atatgccgta cggaaagcca tacggacgtc
    16501 tatcttatat tttttcaaag cctcatagcg caatgtccag cccaccgcct cttcctccgg
    16561 tattccaagc cggcagcaag cctgcgccaa gtcgatgaac agcagttgga tatcatcttc
    16621 cgggctttct gaaaaccgac gcgtcatctc catcaggatg acactgaaca gcgtggcgat
    16681 ctgcccgttc cgatccgctc ccggagccat catctccaac ggatcccgaa ccggagaagg
    16741 cacgatcttc aagtcacccc cgtccggcat ctgcaaaggt tgctcgatcc ggatcgccac
    16801 cgcatccgga ttgtaatagg cgtccggatc cacactcatc cggcaccccc gcgacaggaa
    16861 cggttctttc aacgatataa tgctgcccaa ctgcggctgg taatgccgca ccgccagctg
    16921 ataagccgca gcatgaaaca tacgggcctg ctcctctttt ttcggcagcg agccgtcggg
    16981 cagcacaaaa ggaaccacga tcttgaccga acgcccgctc agcccgacga acgccagcaa
    17041 ggtctgcggc agggcggcag cttcacggcg gacggcctcc gcctcattct ggctttccaa
    17101 gccattcact tccaacaaga catacccgtt atagcgcctc aactgtattc catcgccatt
    17161 cttcttgaac gtcgagccaa aagccagaac cggtagtttt ccggacaaat ccgtggttcg
    17221 tgccaaaaac gccatattca attttcgacg aaccgacagt atcgcttccg catctttgcc
    17281 gtttttcagc aacccgacaa tatattccat atcacgcgag tgcatccgca acacgccttt
    17341 tttatgcctg taatatgtga tttgcattac caaggatttc tttcgaattt gacaaatttc
    17401 atactctttc tcacgcaggg agccatcctg aaacagacac gacgcgcctt cacccgatgg
    17461 ggagtacatt ttttcggatc ttcgaagcct tcgctccctg ccgaaagata aaaatcaccc
    17521 aacccgtcca actccacgga atagccgtct ttcaacaatt caagaatcat ccctccgatc
    17581 tcgcaaaccg aagcgaacac atcacctcgg ctcaacgagc aacgatcggc aaccaaatca
    17641 gccagctttt tcgttgaaac ccgcccgcac gtaaccggaa caccataata gcgtacttta
    17701 tcttccgctc ccgtcttgtc cagtttttgc cggactacat agtaatgtgc cataaataac
    17761 agtattttta atattaaaca accagatatt cttctcaaga cgcccatttt aacacttttg
    17821 acacccccat ctgaacggta tcagcacccg ggtctcaccc cttccgacac ccggatgacg
    17881 ggcttctttt cttattacaa atatacaaat aaaacatcta taatgcaaat atttacagca
    17941 ctttattcaa ttatatctac acttattttt ccccagcacg aagacagaag catgtgatat
    18001 acgacatgat agtatgatag tatgaaatga tagttgaaaa tagatactat catattttta
    18061 taaactaata tacagatatt tatctgaaaa tatgatagta tgatagttag atttaaaaaa
    18121 aatcgtatgt atataatagg tggatgttta cagcagctta tttatattgc ttacaggagg
    18181 aagacttaca tggatggcaa ccctaaataa cacatcgtcc cgtttccatg tttgacatta
    18241 cagctatcaa acacaagaaa caggacgatt ttgcatatct aagttctttt ccgattgacc
    18301 ggacttacat aaaaatttcg acaaacgtgc cattccgaca tagcacacaa ctacatcatc
    18361 gagctaaaag caccttattt tttgcaaccg tcgcctgaaa ctctttcagg tagaacggtt
    18421 cgaaataggc ggtgtcttca aacttgccgg cggcaaaagc ttgttccgag agcggaatca
    18481 tgtttacggc aagaggatgg atgtcctcga taaagatggc attcggagaa gtgatgaccg
    18541 atttgcattt ggaagcaccg ttgccaaaga aacaaacttt ccctttttcc agataagaag
    18601 catacgtacc gacttccaca atatcggccc tcgtctcgcg gacaggcttt aaggaagcat
    18661 cgtagatagc ggcataaacc tccatacgcc gggcatccaa catagcacaa taaagacaat
    18721 catcagtaat agagacgatt tgcgaatcac ccttactgtt gacagtagca gccatgatgt
    18781 ccaacgtatg aatgccgatc agaggaatac cgaaaccaaa gcaaagacct ttagcgacag
    18841 acactccgat acggagtccg gtataagaac caggaccgct actgaccgct acggcatcca
    18901 aggctttctt ccccttcttt ttcaatacgg aaagagcttc ttcaacaaat acgcctaata
    18961 gggctgcatg cgaagggccg tcgaacgaag ccttcgcaaa aaggacttca ccatccatag
    19021 acaacgctac agagcataca gaagtcgatg tttcgatatt taatatacaa gacattttaa
    19081 ttgacaattg acaattgaca attgacaatt agaatatgtg tcaaaagcca atcggttgat
    19141 aatggatgca aaagtataaa acataactgt aatctcatga tcaaaaccga ttttattaag
    19201 gctgacacgg atggtttcgg ctttttccca attatattgt caatcgtcaa ttgtcaatta
    19261 tcaattgatt agctatcttt gcacaaattt ttagaacaat gatacaatca atgactggat
    19321 tcggtaaggt tacagccgaa cttccttcta aaaaagtaac cgtagaaata aaagctctga
    19381 acagcaagca actggatttg tcgacccgca ttccttccat ctacaaagaa aaagaaatgc
    19441 aaatacgcag tttgttactc cagtcgcttg aacgtggaaa agtcgaattt aatatatttg
    19501 tcgaatatat cggtaaagac acgcccacac agatcaactt ggctgcggta gaaaactatt
    19561 acaatcaaat caaagatatt gccgaccgcc tgaacatcgg acttcccgcc gactggttcc
    19621 agaccctgct ccgcatgccg gacgtgatca agacagaggc ccaggaagta aacgaagagg
    19681 aatggaatgt ggttgagaaa gcgatcaaag aggccatagg gcacctttgc gatttccgta
    19741 ttcaggaagg cgccatgtta caaaagttgt tcgaacagaa aattgccaat atctcccgcc
    19801 tgctttcaga agtagaacag tatgaaaagg agcggatcga aaaaatcaaa gcccgtatca
    19861 tggacaatct cgaaaagatt gccggacagg actacgacaa gaaccggttc gaacaggaga
    19921 tgatctatta tatcgaaaaa ctggacgtaa acgaggaaaa gaaccgcctg gacaaccacc
    19981 tgaaatatta catcagcacg atggagagcg gacacggaca aggtaagaaa ctcggtttca
    20041 tcgcccagga aatgggacgt gaaatcaaca cccttggttc gaaaagcaac catgccgaga
    20101 tgcaaaaact tgtcgtccag atgaaagacg aactggaaca aataaaagaa caagtattaa
    20161 acgtattata aaaacgatat atggctggca aactgatcat attctccgcg ccgtccggtt
    20221 cgggcaaatc cactatcatc aatttcctgc tgaagcagaa tctgaacctg catttttcca
    20281 tctcggctac cagccgggcc ccacgtggta cggaaaagga cggagtggaa tattatttcc
    20341 ttacaccgga tgaattccgt gcccgtatag cagcaggaga tttcctggaa tacgaagagg
    20401 tctataccga caaatattac ggcacgctga aaagcgaggt ggaacgaagg ctgatgagtg
    20461 gcgataacgt catattcgat gtcgatgtcg taggaggttg caacatcaag aagttttatg
    20521 gcgaccgtgc tctttcggtc tttatccagc ccccttcgat cgaagatttg cggagtcgtc
    20581 tggaaggacg cggtacggat gctccggaag taatcgaaag ccgcattgcc aaagccgaat
    20641 ttgaactggg ttttgccgac aaatttgacg taatcgtggt gaacgacaag ttggaagtcg
    20701 cagaaaaaga agcactaaaa gtgataaaag agttccttaa aaaagcatga acggcaagaa
    20761 gttatccaag aaatggctat atacattcat tggtatagca tttgtcgctc ttgccacttg
    20821 tacagccgcc ctatattata aggagtatat catagcgacc ggtaccggat tggtattcgg
    20881 tgcacaagtc ataaatatca tcaagtggaa acgggactga aagaaaatac ggccagcaaa
    20941 cgtaaaaccg gcatttattc cggttcattc aatccggttc atatcggcca tctggcatta
    21001 gccaactggt tgtgtgaatt tacggagctg gacgagctat ggtttctgat caccccccat
    21061 aacccgctaa aagagaagga agaactgatg gatgaccggc ttcgctatga actggttaaa
    21121 aaatccatcg ctggttaccc taagttccac gccagtgact tcgagttttc ccttcttcaa
    21181 cccacttata ccatcaacac actccggaca ttggaagcaa gttatccgga ccgtgaattc
    21241 tatttcatca tgggtgcaga caattggaaa tatattaccc ggtgggtaga atacgaagcc
    21301 atcatttcca attatccgat cttcatctat ccgcgcaaag gattcgatgt tgaaattccg
    21361 gcacaatatc ctcacataaa aaaagtagac gcccctttgg tcgaaatatc ctcaaccttt
    21421 atacgcgaag ctttcaagac cggaaaagat gtccgcttct tcctgcccga agccatacgt
    21481 aatctgcctt ttccattaca aaacaatacc ttttaagaac ataaagcgta aagtcgcata
    21541 cgtttttagg caataagtaa gaaaagtttt gtatttttgc gccgtattat acaaaataat
    21601 agcgtaatga atctattaga actgagtgaa caggaaatca taagacgtaa cagcatggag
    21661 cagttacgcc agatggggat agaaccttat cccgcagctg agtatgtaac gaatgcattt
    21721 tccaaagaaa taaaagagaa ttttaaagac gatgcagagc cccgccctgt aagtattgcc
    21781 ggtcgcatca tgagccgccg catcatggga aaggcttcct tcatggaatt gcaggattca
    21841 gaaggcagaa tacaggttta tatctctcgt gacgacattt gcccggaaga aaataaagat
    21901 ctgtataaca ttgttttcaa gaaattgctc gatatcggcg actttgtcgg aatcaaaggt
    21961 ttcgtattcc gtacacagat gggcgaaatt tccgtccatg cacaagagat aacggtatta
    22021 tccaaatcac tcaagccgct accggtcgtc aaatacaaag acggtgtagc atacgatgga
    22081 ttcaacgatc cggaattgcg ttatcgccaa cgctatgtcg acctggtggt caatgatggt
    22141 gtaaaggata ttttcatgaa acgtgcggca gttatcaaga ccatgcgtac cgccctggac
    22201 gaagctggat atacggaagt ggaaactccg atcctgcaat ccatccccgg aggggcaagc
    22261 gcacgtccgt tcattacgca ccataactcg ctggatatcg acctctatct gcgtattgct
    22321 accgaactgt atctgaaacg attgatcgtc ggaggtttcg aaggtgtcta cgaaatcggt
    22381 aaaaacttcc gtaacgaagg tatggatcgc acccacaatc cggaatttac ctgtatggaa
    22441 ctttatgtcc aatataagga ctacaactgg atgatgagct tcaccgaaca gctgttggaa
    22501 cgtatctgta tcgccgtcaa cggtacatgt gaaagtgtag tcgacggcaa gaccatcaac
    22561 tttaaagctc cttaccgccg tctgccgatt ctggatgcca tcaaggaaaa gacaggttac
    22621 gacctgaatg gcaagagcga agacgagata cgcacgattt gcaaggattt gaaccttgaa
    22681 atcgatgaaa caatgggtaa aggcaagctg atcgatgaaa tcttcggtga attctgcgaa
    22741 ggcacgttta tccagccgac tttcattatc gactacccgg tcgagatgag tccgctaacc
    22801 aagatgcacc ggagcaaacc tggattgacc gaacgtttcg aattgatgat caacggtaaa
    22861 gaagtggcaa atgcctatag tgagctgaac gatccgatcg atcaggaaga gcgcttcaaa
    22921 gagcaattgc gcctgagcga aaaaggagat gacgaagcga tgttcatcga ccaggacttt
    22981 ttgcgtgcac tgcaattcgg tatgcctccg acgtctggta tcggtatcgg catcgaccgt
    23041 ctggtgatgt tgatgactgg ccaaacgact attcaagaag tgttgctctt cccgcagatg
    23101 cgcccggaaa agacagtcaa gaaagacacc gcagacaaat atgtcgcact gggtatcgat
    23161 gaagcatggg ttcctgcttt acataaagcc ggatatctca caaccgacac gttggtagat
    23221 gctaatccca acaagctgag acaggaactc tgcgaaatga ataagaaata caaactggaa
    23281 ttgcaaaacc ccactgccga agaagtagag gcatggattg caggcgcagc caaataagag
    23341 taatactatg aagttgcccg gaaaaattgc aataatggga ggtggtagct gggctaccgc
    23401 cttggccaag attgtacttt ctacacaaga tagtattaac tggtatatgc gtcggccaga
    23461 ccaagtagaa gagtttctgt tgttgggaca taaccccagc tatctttccg ccgtcaaatt
    23521 tgatactgac aaaatcaaat tctacacgga tatcaacaaa gtaatcaaag attcggacac
    23581 attgattttc gccacccctt ctcctttttt gaaacaacat ttgatgaagg tgacgacctc
    23641 catgcaagac aaattcatca tttcggccat caaaggaatc gttccggacg aaaacatgct
    23701 cgtagccgat tattttgccg aatactacaa tgtcccgatt gacaatatcg ctgtcatcgg
    23761 cggtccgtgc catgccgaag agatcgctct cgaacggttg tcctatatca cgctggcttg
    23821 ccctaatatc gagaatgcaa gagctttctc ctccgtattt aagaaccagt atctgaacaa
    23881 ctcctgttgc aaggatgtta caggtattga atatgcttcc gtattgaaaa acgtatatgc
    23941 catcgtcgca ggtatctgcc acggtatgaa gtacggagat aattttctgg cagttttcat
    24001 ctgcaacgcg atcgaagaga tgcgtaactt cctcaacgcc gtacatggcc tggaacggga
    24061 tgtgacagat tcggtatatc tcggtgatct tctggtaacc gcatattccc gcttcagccg
    24121 gaaccgtacg ttcgggacca tgatcgggaa aggttattcc gtcaaaatag cccagctcga
    24181 aatggagatg atcgccgaag gatattacgg gacaaaatgt attcgggaga taaacgaaaa
    24241 atataaagta aacatgccga tcttggatac tttatatagt attctatacg aaaagaaatc
    24301 gccgactacc gcgatacggc agttgactga aacatttaaa taataatgta aatatgaaga
    24361 acatcagtct taacattgac aaagcgctgg gtactgtgac gaaagaacag gtgtatgctc
    24421 aggctgcaaa ggcccacgaa tgtaatgtca ctttacaaaa tggtaatggt gcaggtaacg
    24481 actttttagg ttggttgcac ctcccctctt ctattacaga tgctgaactg acagacatcg
    24541 aaaatacagc taacgtactt cgttctaaat gtgaagttgt tgtcgccatc ggtatcggcg
    24601 gtagctattt aggaacaaaa gcagtggtag aagcatta
//
