LOCUS       c00025_gnlPro..        17844 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PKPLCHIH_25.
ACCESSION   c00025_gnlPro..
VERSION     c00025_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 19:53:22
            Original ID  :: gnl|Prokka|PKPLCHIH_25
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 17844
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..17844
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[4864:7844]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      4865..7844
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..17844
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..17844
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             456..665
                     /locus_tag="ctg25_1"
                     /transl_table=11
                     /translation="MKRSLHRHETLVGLFLLVFRADDVPQFHLVADLLFCDPSQASGDF
                     GAVLFHTEQIGGGDVRSIDFYILY"
     CDS             1333..4437
                     /locus_tag="ctg25_2"
                     /transl_table=11
                     /translation="MNKKFSTLLTMGLLATSSLCGSAWAQTAPTINGIELEKVAAPANN
                     AAWTGGPYVLVADEDGTLEGSDLLLQAVVSEDGKTVKYYGENLSAFATGAKLKEITWTF
                     TETPVKDVAGVPNGYYYTLTSAASGKPLTVNQSGDLIEKLENCKLDAANHLYTQFSVLS
                     NDFTSCFLQGSGLYPYAGGAGLNPVSLTRAELTSIVGLTGSKLYLYKLKTQELVDQVAV
                     EAMNETMAGEGFNFDFTPKKKLDWANDVLSDVKLKAFYVDNDFDLGNDMKIPAGVYFAT
                     SYPEELVGTDKIADSDLFKQCTFIAIDPTGNYDINATDRDNGLGYELITMQGSEMNFFH
                     GAATSDNFSHAEEVFVGNACFVVEVPNAVTAPETYNIKAKNIHVFVTATDNAAKKHVAK
                     AGLYIGCIADQNKNYMVTTVVTDALAFTTTNTTLLDGDGLVGFLQEEDAPSVYTIQFVS
                     GEKNEGASEYEQYLTVNKPAGFELASTVDFNEADPMYQFVVTGVDKTNKTITLANRQTK
                     VDFTVSLYENEDGVYTVLPATGSKDKVYVEYINGTVGNNSKDEVVTFEAIDLTNMKIVL
                     TPYTVEDKFATFVNRADNMGLVQFELALNSDIAPAFYVGGEKDVDGNLAPNKDILAYAD
                     ADSMVQFELIKSKKPVNVLNNYIYLDGKRIRTSTERDTVAFYTYAVKAFDDANDRYLSN
                     TWELEVATDVSADEFIIKQNLDGSVSLIKAATTTDVNGAFAMVNDLKKDRETAWKDAYN
                     YELEHKIDKGLKTFMVDETPAVSLEAVPQHVSFALTRGGFLTNKDNDAFQSIATEASED
                     LTFWVDTVKSDKNIPTFYISKAGHFLYNAEDSVEYYEARGNYRFNLENQKGEAAKLIFK
                     AGELVSSDTLRTVVDGKSVLVAEKDNAPKKIKGGLDNFQFQIIKAEDGSDEYVIRQGRA
                     NYVQMINSYFYLEANKNTAVRFLIESQSTPTANEGVAVSEVKVLAGEGNVTIAGAAGKK
                     VVISNILGQVVANTVISSDNAVIAAPAGVVVVAVEGEAAVKAIVK"
     CDS             4865..7105
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg25_3"
                     /sec_met_domain="Gly_radical (E-value: 7.4e-46, bitscore:
                     146.7, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 1.3e-281, bitscore:
                     926.7, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKFENENWAQFKGETWKKEINVRDFIQNNYKPYNGDDTFLVPSSE
                     KTKKVWNKLTEMFKVEREKGVYDAETKLPQGIDTYGPGYIDKENEVIVGLQTDAPLKRG
                     IFPKGGIRMVENSLEAYGYHLDPMTKEIFTKYRKTHNEGVFSAYTDEMIAARRSAIITG
                     LPDAYGRGRIIGDYRRVPLYGTQILIEEKKRFQKRLDIQELTEEIIQSREEITEQIKAL
                     KAFEKMCAGYGFDVTRPAKDAREAVQFLYLAYLAAVKDQDGAAMSLGRTSTFLDIYIEK
                     DICEGKLTEEEAQELIDQFIIKLRIVRFLRTPEYNDLFSGDPVWVTESLGGQGVDGRSL
                     VTKTSYRYLHTLYNLGPAPEPNLTVLWFNNAPDNWKNFCAKVSIDTSAIQYENDDLMRP
                     DYGDDYGIACCVSPMKIGKQMQYFGARANLAKCLLYAINGGRDEKSGVQVAPRFEPITS
                     EYLDYNEVMEKYEQMMRWLAKVYVNALKIIHYMHDKYAYEAFEMGLHDGDVERIRATGI
                     AGLSIVADSLAAIRDTKVKVIRDERGLAVDFEREGEYVPFGNNDDRTDSIAVDITEKFM
                     EYLRQHQTYRKATPTQSILTITSNVVYGKKTGTTPDGRPGGTPFAPGANPMNGRDTKGA
                     VAALASVAKLPFQHAHDGISYTFAVSPATLGKERDIQINNLVSLLDGYFTPDGGQHLNV
                     NVFDRDLLLDAMEHPEKYPQLTIRVSGYAVNFVKLTREQQLDVISRTINSSL"
     CDS             7122..7844
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 75.2;
                     E-value: 2e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg25_4"
                     /sec_met_domain="Radical_SAM (E-value: 1.3e-35, bitscore:
                     114.9, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLGRIHSLESFGTVDGPGIRFVVFMQGCPLRCLYCHNPDTWEVKS
                     GTPYRMEPEALLAEVLRYKNFIAKGGVTVTGGEPLLQPEFLKEFFRLCRENGIHTALDT
                     SGYICSGKALEVLEQVDLVLLDIKTIDAGLHPRLTAVKLDNTLRFLDELEKRGIPVWIR
                     HVIVPGLTDDDEALSKLAEYISSYNVVQKAELLPYHTMGAYKYEAQGLDYKLKGVEPLS
                     AERLANAKAIFMKHGVTV"
     CDS             complement(7847..8152)
                     /locus_tag="ctg25_5"
                     /transl_table=11
                     /translation="MRRASLYNTFSASLLLVCNACLSSCVSQIPLTKEKPVNNSTYQVE
                     YLFEHEGCKVYRFMDMGHYIYFTNCEGDVTSIESDSVRTVNRISRKPIIIKEQTLD"
     CDS             8428..8994
                     /locus_tag="ctg25_6"
                     /transl_table=11
                     /translation="MEPIINSQVPEFKVQAFQNGSFKTVSSEDIKGKWAIFFFYPADFT
                     FVCPTELVDMADKYGKFQEMGVEVYSVSTDSHFVHKAWHDASETIRKIKYPMLADPTGA
                     LSRAFGVMIEEEGMAYRGTFLVNPEGKIKIAEIHDNGIGRNADELLRKVEAAQFVASHP
                     NEVCPAKWKKGEATLKPSIDLVGKI"
     CDS             9116..10681
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg25_7"
                     /sec_met_domain="Pyr_redox_2 (E-value: 6.2e-48, bitscore:
                     155.0, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLDSAMKDQLSGIFSGLVSQYVFDIQVAPDHESRQELIDLLGDVA
                     SCSDHLSCSVADGEGLQFTIVKDGMPTGIRFRAVPNGHEFTSLLLAVLNSDGKGKNIPD
                     ESICARVRALNGPIKLTTYVSLTCTNCPDVVQALNVMATLNSRITHETVDGAINQKEVE
                     AMKVQGVPSVFADGKLINVGRSDLGELLSKLEAQYGINEGGVDNSVEKPVKNYDVLIVG
                     GGPAGAASAIYSARKGLNVAVIAERIGGQVKETVGIENLISVPQTTGKQLANDLLMHIN
                     DYPVDILEHRRVDKVELDGSAKFLTTSTGERFSAPALIVATGASWRKLNVPGEADYIGK
                     GVAFCPHCDGPFYKGKHVAVVGGGNSGIEAAIDLAGICSKVTVLEFMDELKADQVLQEK
                     AKSLPNVEVFLHSQSLEVVGDGDKVTGLRVKDRKTDAERVIDLDGIFVQIGLAANSGVF
                     RDVVETNKPGEIVIDAHCRTNVPGIYAAGDVSTVPYKQIIIAMGEGAKAALSAFEDRMR
                     GLIG"
     CDS             12203..16474
                     /locus_tag="ctg25_8"
                     /transl_table=11
                     /translation="MNKKFSTLVASMLLATTVGTVSAQNLEFTKSALPTNVRVESVADG
                     KCYQLTDGWNVLVMQKVSTEKGDRFILKYVPYYAANIGESLWYVTVDKDNKENGVAFKF
                     MNLAYNYPISFDPAKIQDYKPGKTYEGSYLAGEAVAWAWMRSEAGEGLNVGKTPEAYFK
                     TDSVMTLIPNADGTVAAVKYDVRETDKLAQLNIRPAVAGPVWLGKNDLNSMLQTQDATN
                     GKTSFSFEKDVTEGLANLWSAGKGHAYEAVDAVGESTLSYGAVADAAAEKDAAMLAANE
                     AEKKVEAAVKALADAESEYYVLAQKIQNVESEKVEKGRELVNQSWIYNFLNESEDVTKQ
                     AILQKKQSIATSSALNEEAKKQLAELAEKLEAAQNEYKDAVAAQTALQNSINNATDAWI
                     VALDVKNKAVDQKSRYAKWGTAMRKYFNETSDVHYVSDMGYAPNDKPQAWNSYFDAAKV
                     IDEAEKEAFVEYGHRLYAILKEANNGVDISMSASAYKNQNDKAFTNGVNALNTEEDETV
                     EKAAEAVIASEGAIASISKDLGVAIGVAEEKKQAEKAASTAYDEMFKAYGVHSQALEEA
                     EKELKELEEELASVQAELKEVSAKKVELETAIFNYTQQIASLNEQLMALDGEKGAAYWT
                     WVDARYAHKDAERAAIKASEVFENIRLEKSFNWLSLKAGKNAKGQDTYLMVDTAYLNGS
                     AGEEIAGIQHLGFATREHEADFKSVNNLAARDINGRFNFRFFYWPTQDSLRIEADGYNV
                     KNVTTKYWKDRTNSEIDIFATSAKGQENNLVKIAVLGGARREATIGSSEELKGTGIYTY
                     NDRIGLSLSPAAHNAVLEPGIYFMDVVNGADAQKNGARLMGDLNGWNLTKVAPAEWDVM
                     NFEHMPAAKWVVNQNTNEFGGYPEIWNQETGATLNNGSYKVLADGNIVINYYYNNEEAW
                     LANDTLKLTKTVSNRLGFFNDDAKNVNYTLNYLNVGNDLGVTIGNSTVGNDTILRVSAD
                     EATKFELVKSGSSYNTPIFEKDTIFQTYYQIRVNDPYKFANNQKYVQVSEVGGTEMMVV
                     TEGAENGSVFTLKEVNCVDGTHYYALLTEGKKAGVIDATGLIKAENVATESTTSAFALV
                     ADTTALYREFTADELGENGAMKFYRVNSTAKAYLYEGADNLLCVEGKGDDKAEAFNVIP
                     TGVENTLMPQYLIAKDVNFVVGDTVLCDATTHSHATIEEALKCPHSKVTADTTFGRFLV
                     NMIDSVPAVKKYTWEGKYKRLAFLPGYMTAGNLVLDGTTHKVALKLNAHDQAKFSFRLV
                     NEGSNDFLIESESYGKKTAFDGGIAPSANLGGWVKVQNGVPVIINDFEAAMQSDLYNVD
                     TNAGGATANDEITTSEVTIIAGEGNVTIANAAGKKVVVSNILGQVVATQVLTSDNAVIA
                     APQGVVVVAVEGEEAVKAIVR"
     CDS             complement(16549..16764)
                     /locus_tag="ctg25_9"
                     /transl_table=11
                     /translation="MPCIRKSLCKKVENKAPKTKPSPGLVFYLPYTFTGSQQNELYFNT
                     LVLLILNRLFACHRVITVCTARGQTF"
ORIGIN
        1 taacaacagc ggggattttt attggttttc cttgcgacaa aagaagaact gttttgagaa
       61 aaacggttct ttttgtttca atatcaccct gattaggtag caagaggcgt ttttttactc
      121 acatataggt attgtaggag gccggaggta cccgtatctt tgcaatgtca ttaagaaagt
      181 aacactatta gtataatcgc tatatcaaaa ccttttgcta tttatgtaag catataagat
      241 gattaactat atcggaaagt ttttattggt tattttcgat ataaaaaaga agcctctctg
      301 tgaagagagg cttctttttt atgtttccgt ttcccattag cttctgtccg gaatctgttc
      361 ggcgtcgagt cttggacttg ttcccgcaag ggtatgtttg ctacttcggc tgtgccaaaa
      421 caattacatc ggcttggcac aaccgtttcc tcggcatgaa acggtcgtta cataggcatg
      481 aaacactggt cggtttgttt ctcttggtat ttagggctga tgacgtgcca cagtttcacc
      541 tcgtcgccga tctgttgttc tgcgatcctt ctcaagcaag tggtgacttt ggagctgtct
      601 tgtttcatac agaacagata ggaggcgggg atgtcagaag catcgatttt tatatattat
      661 attaatgtat tatagttgtt tgatccgtct gtaacggacg ttgatgtaaa gatacataat
      721 aatgtaaggt tttgcaagtc ttgaaaccgt tattgagcaa gcaatcgata tctccgtatt
      781 ttgtatatct ttaacaaaag gggacgcttc tccaagagga aattacgaaa ccagttgttt
      841 ttgccatttt ttcttccgat gcgagtaaag gatgtttgtc ttgtatgtgg ctgataatct
      901 ttgttttaat gaagatgtaa agaggtttgg cgaatgattg aaaacagtta cttttatata
      961 tggctttagc tacttttggg tgctataaat tgttgttaat aagaagtata ggtgtatgag
     1021 aagaaaaatg gtgaaaaaac gtacgttttt gttcgccatt ttcactgcac aaaaatacaa
     1081 ctacttttta aacctgcaat cctttcttcc aattattttt ccttttctat attctttctt
     1141 atcaatcaga tagcttaaca agtacgaaaa accagctttc caacacaaac cctccagaaa
     1201 gcccctcaaa aatgactaaa aaaaacgtac gttttatctc gtcaaaatac aggaatttgg
     1261 taaaaacctg ttaaacagga agtaagaacg atattcaata tacatattat tattaattaa
     1321 acattttaga ttatgaacaa gaagttttct actcttttga caatgggctt gttggctaca
     1381 agttcgttgt gtggtagtgc ttgggcgcag actgctccta caattaatgg gattgaattg
     1441 gagaaggttg ctgctcctgc caataatgct gcatggacgg gcggtcctta tgtgctggtt
     1501 gctgatgagg atggtacgct tgaaggctct gatcttttgc tgcaagcagt agttagtgag
     1561 gatggtaaaa ctgtaaagta ctatggtgaa aatctttcag ctttcgcaac tggtgctaag
     1621 ttgaaagaga ttacttggac ttttactgaa acacccgtga aagatgttgc tggtgtacct
     1681 aatggctatt attacacttt gactagcgct gcttctggta agccgttgac agtaaatcaa
     1741 tcaggagatc ttatagaaaa attagaaaat tgtaaacttg atgcggctaa tcatttgtat
     1801 actcaattct cagtgctgtc taatgatttt acaagctgct ttttgcaagg ttcaggattg
     1861 tatccctatg caggaggggc agggttgaat cctgtttcat tgacacgtgc agaacttacc
     1921 tctattgtag gtttaactgg aagcaagttg tatctctaca aacttaaaac ccaggaattg
     1981 gttgaccaag tagctgttga agccatgaac gagactatgg ctggcgaagg ttttaacttc
     2041 gatttcactc ctaaaaagaa attggattgg gcaaacgatg ttctgtctga tgtgaaattg
     2101 aaagcgtttt atgttgataa cgattttgac ctaggtaacg acatgaagat tcccgcaggt
     2161 gtttactttg ctacttctta tccggaagaa ttggtcggaa cagataagat tgctgattcg
     2221 gatctgttca aacagtgcac gttcattgct atcgacccga caggcaacta tgacatcaac
     2281 gcgactgacc gtgataatgg cttaggttac gaactgataa ctatgcaggg tagtgaaatg
     2341 aactttttcc atggtgctgc tacatctgac aacttctctc atgcagaaga ggtattcgta
     2401 ggcaatgctt gtttcgtagt tgaagttcct aatgcagtga ctgctccgga aacatacaat
     2461 atcaaagcca agaatattca cgtgtttgtt actgcaacag acaatgcagc taaaaaacac
     2521 gtcgccaagg ctggtcttta tattggttgt atcgctgatc agaataagaa ctacatggta
     2581 actactgttg ttactgatgc tttggctttc actacgacta atactactct gttggatggt
     2641 gatggtttag ttggcttctt gcaggaagaa gatgcaccat ctgtttacac aatccagttt
     2701 gtaagcggtg aaaagaatga aggtgcttct gagtatgaac aatatctgac tgtgaataaa
     2761 ccggctggtt tcgaattagc ttctactgtt gatttcaacg aagcagaccc gatgtaccag
     2821 tttgttgtaa caggtgttga caagacaaac aagacaatca ctttggctaa ccgtcaaaca
     2881 aaagttgatt tcactgtttc gctgtatgaa aacgaagatg gtgtatatac agtacttccg
     2941 gcaacaggca gcaaggataa ggtatatgta gaatatatca atggtacagt tggaaataat
     3001 tcaaaggatg aagtcgttac ttttgaagct attgacttga cgaacatgaa gatcgtcctg
     3061 actccgtaca ctgtagaaga caagttcgct acattcgtga acagagctga caacatgggc
     3121 ttggttcagt tcgaattggc ccttaacagc gatatcgctc cggcattcta tgttggtggc
     3181 gagaaagacg tagatggcaa tctggcacca aacaaagaca tcttggctta tgccgatgca
     3241 gacagcatgg ttcagtttga actgattaag agcaaaaagc cggttaatgt attgaacaat
     3301 tacatctact tggatggcaa acgtattcgg acttcaacag aaagagacac agtcgctttc
     3361 tatacttatg cggttaaggc gtttgatgat gcaaacgaca gatatctgag caacacttgg
     3421 gaacttgaag tagcaacaga tgtgtctgca gatgaattca tcatcaagca gaatttggat
     3481 ggttccgtat cattgatcaa agctgcgact acaactgatg ttaatggagc tttcgcaatg
     3541 gttaatgact taaagaaaga cagagaaact gcttggaaag atgcatacaa ctacgagttg
     3601 gagcataaga tcgacaaagg cctgaagacc ttcatggttg acgaaactcc ggctgtcagc
     3661 ctagaagctg ttccgcagca cgtatctttc gcactgactc gtggcggttt cttgacgaac
     3721 aaggacaacg atgcgttcca gagcatcgcg acggaagcaa gtgaagactt gacattctgg
     3781 gtagacacag ttaaatctga caagaatatt cctacgttct acatttctaa ggctggtcac
     3841 ttcttataca atgcagaaga ctctgttgag tattacgaag ctcgtggcaa ctaccgcttc
     3901 aacttggaaa accagaaagg tgaagctgct aagctgatct tcaaggctgg tgaattggtc
     3961 tcttccgaca cattgcgcac tgtcgttgac ggaaaatctg tcctggtagc agaaaaagac
     4021 aatgctccga agaaaatcaa aggcggtttg gacaacttcc agttccagat catcaaggct
     4081 gaagatggta gcgatgaata tgtgatccgt cagggtcgtg caaactatgt tcagatgatc
     4141 aatagctact tctatctgga agcaaacaag aacacggctg ttcgcttcct gatcgaatcc
     4201 cagtctactc cgacagccaa cgaaggcgta gccgtatctg aagtgaaagt tctcgccggc
     4261 gaaggcaatg tgacaatcgc aggtgctgcc ggcaagaagg ttgtcatcag caacatcttg
     4321 ggtcaggtag tagcaaacac agtaatctct tctgacaacg ctgtaatcgc tgctccggca
     4381 ggcgtagtag ttgtagctgt tgaaggcgaa gctgctgtaa aagctatcgt taagtaacga
     4441 ttgatactaa aaaaacaata ctgtctatcg taagggtggt tagtgaacca cccttacaca
     4501 ggcacaatga cattttataa tcaaataatt ctagacaacc tgcgtgaaac cgtatgtaag
     4561 aggttttctt gatctacggt ttcaattacc ctgcgacagg cgaacgagcg gttggattta
     4621 atattaataa tactaaagta atgaaattaa aagttctact gcttttccct ctgtgaagac
     4681 cggacggcag acaaaaaaca ggcctcggcg gtattcgtac tgccggggct tcgtttttat
     4741 ttcccttatc cctatttgta ggtattttct ccggtttaac atccctcgtc ctttacaatc
     4801 cttttcagat agggggaaaa gacgtatctt tgcgtgccta aaccgaaata gacaagataa
     4861 gcttatgaag tttgaaaacg agaactgggc gcagttcaaa ggagaaacct ggaaaaagga
     4921 gatcaatgta agagacttta tccagaacaa ttacaaacct tataacggag acgatacgtt
     4981 cctcgtaccc tcttcggaga aaacgaagaa agtgtggaac aaactaaccg agatgtttaa
     5041 ggttgaaagg gagaaaggag tatatgatgc cgaaacgaag cttccccagg ggattgacac
     5101 atacggaccc ggttacatcg ataaggaaaa cgaagtaatc gtcggcttgc agacagatgc
     5161 cccgttgaaa cgtggtatct tcccgaaagg cggtatccgc atggtcgaaa acagtctgga
     5221 agcctatggt tatcatctgg acccgatgac aaaagagatc ttcaccaaat acagaaagac
     5281 gcacaacgaa ggcgtttttt cagcctatac agacgagatg attgcggcac gtcgttccgc
     5341 catcattacc gggttgcctg atgcttacgg acgcggacgt atcatcggtg attaccgtcg
     5401 tgtacctctg tacggaaccc agatcctgat cgaagaaaag aaacgtttcc agaaacgtct
     5461 cgatatacag gaactgacag aagaaatcat tcagagccgt gaggagataa cggagcagat
     5521 caaagcgctg aaagcatttg agaaaatgtg tgccggttat ggtttcgatg tgacacgtcc
     5581 ggcaaaggat gcccgcgaag ccgtgcagtt cttgtatctg gcttacctgg cagccgtaaa
     5641 ggatcaggat ggagcagcca tgtctctcgg acgtacttct actttcctcg atatctatat
     5701 cgaaaaagat atttgcgaag gcaagctgac ggaagaagag gcacaggaat tgatcgacca
     5761 gtttattatc aaactgcgta ttgtccgttt cctgcgtact ccggaataca acgacctgtt
     5821 ctccggcgac cctgtttggg tgactgaatc gctgggcgga caaggtgttg acggccgttc
     5881 gctggtgaca aagacatctt accgttatct gcataccttg tataacctcg gcccggcacc
     5941 cgaacccaac ctgacggtgc tttggttcaa caatgctccg gataactgga aaaacttctg
     6001 cgcaaaagta tcgatcgata cctctgccat ccagtacgag aacgacgatc tgatgcgtcc
     6061 ggactatggc gacgattacg gtatcgcctg ctgtgtgtct ccgatgaaga tcggtaagca
     6121 gatgcagtat ttcggagctc gtgccaacct ggcaaagtgc ttgttgtatg cgatcaatgg
     6181 cggacgtgac gagaaatcgg gtgtgcaggt ggctccccgt ttcgaaccga tcaccagcga
     6241 gtatctggac tacaacgaag tgatggagaa atacgagcag atgatgcgct ggttggcaaa
     6301 agtttatgtc aatgctctga agatcattca ctacatgcac gacaaatatg cgtatgaagc
     6361 attcgagatg gggcttcatg acggagatgt ggaacgtatc cgcgcaaccg gtatcgccgg
     6421 cctttctatc gttgccgact cgctggctgc catccgtgac acgaaagtga aagtgatccg
     6481 tgacgaacgt ggtttggctg tcgacttcga acgcgaaggc gaatatgtac ctttcggaaa
     6541 caatgacgac cgcacggaca gtattgctgt cgacattacc gagaagttca tggaatatct
     6601 gcgccagcat cagacatacc gcaaggcaac tccgacacaa tctatcctga cgatcacatc
     6661 aaacgtggtt tacggaaaga aaaccggaac gactcccgac ggccgtccgg gcggtacgcc
     6721 gttcgctccg ggagctaacc cgatgaacgg acgcgatacg aaaggggctg ttgccgcttt
     6781 ggcttctgtt gccaaactgc ctttccagca tgcgcatgac ggtatttcct atacatttgc
     6841 cgtttcaccg gctacattgg gtaaggagcg cgatattcag ataaataatt tggtgagcct
     6901 gttggatggc tattttacgc ctgacggtgg ccagcatctg aatgtgaacg tgttcgatag
     6961 ggacttgttg ttagatgcaa tggagcatcc ggagaaatac ccgcagctta cgatccgcgt
     7021 ttcgggctat gccgtcaact tcgtgaagct gacacgcgaa cagcagctcg acgtcatctc
     7081 gcgcaccatc aacagcagtt tataattgtc cattgattaa tatgttgggg cgtatacatt
     7141 ctttagagag tttcgggacc gttgacggtc ccggaattcg ctttgttgtt ttcatgcagg
     7201 gatgtccgct tcgttgtctg tattgccaca atccggatac ttgggaggta aaaagcggga
     7261 cgccttatcg aatggaaccg gaagccttgc ttgccgaagt gctgcgctat aagaatttta
     7321 tcgctaaagg tggtgttacc gtgaccggtg gtgagccttt gttacaacct gaattcctta
     7381 aagagttttt ccgcctttgc cgtgaaaacg gtattcatac ggcgttggac acttccggct
     7441 atatctgttc cggtaaagca ttggaggtgc tcgaacaggt cgatctggtt ctgttagata
     7501 tcaagacgat cgacgccggt cttcatcccc gtttgacggc cgtaaaactc gataatactt
     7561 tacgctttct tgatgaactg gagaaacgcg gcatccctgt atggattcgc cacgtgatcg
     7621 tgcccggcct gacggacgat gatgaagcct tgagcaagct ggccgaatat atcagttcat
     7681 ataacgtggt ccagaaagcc gaacttctgc cttatcatac aatgggagct tacaaatatg
     7741 aggcacaagg cctggactat aagctgaaag gtgtggaacc gctttcggca gaacgtctgg
     7801 ccaatgcgaa agcgatcttt atgaaacacg gagtaaccgt ataagcctaa tcgagtgtct
     7861 gctctttgat gatgatcggt ttacggctga tccggttgac tgtgcggacg ctgtcgcttt
     7921 caatactggt aacatctccc tcgcagttgg tgaaatagat gtaatgtccc atatccatga
     7981 aacgatagac cttacaccct tcgtgttcga acagatattc gacttgataa gtggaattgt
     8041 ttaccggttt ttcctttgta aggggtattt gtgagacaca tgaagaaaga catgcgttgc
     8101 aaacgagcaa tagacttgct gaaaatgtat tatacaaact agctcttctc atcttcgaat
     8161 atttttaagt taacatccaa agttaacaat taaagaatca catggtatga tcgaaaggta
     8221 ttttacctac aattaggtat atttttattg ttccggaaaa cattactttg cttcctattg
     8281 tcatagtaga taagtatgct tgcagataga aatccgtcta tcggcagata aaaattatca
     8341 atttgaaaaa ttctttcaat cagtatctta cgatttacct ttgtagggta aacaaaaata
     8401 gtagtaacaa attaaatagt aaaaatcatg gaaccaatta tcaattcaca agtacccgaa
     8461 ttcaaagttc aagcttttca gaatggtagt ttcaagacag taagtagcga agatatcaag
     8521 ggcaaatggg ccatcttttt cttctatcct gccgacttta cgttcgtatg tccgaccgaa
     8581 ttggtcgata tggctgacaa gtacggcaaa tttcaggaaa tgggtgtcga agtatattcc
     8641 gtaagtacag actcgcactt tgtacacaaa gcatggcatg atgcttccga aacgatccgt
     8701 aagatcaaat atccgatgct ggcagacccg acaggggctt taagccgtgc gttcggtgtg
     8761 atgattgaag aagagggtat ggcttatcgc ggtacgttcc tggtaaatcc cgagggaaag
     8821 atcaagattg ccgaaatcca cgataacggt atcggccgta atgcagacga attgcttcgt
     8881 aaagttgaag ctgcccagtt cgttgcttct cacccgaacg aagtttgtcc tgcaaagtgg
     8941 aaaaaaggcg aagcaacctt gaagccgagc atcgacttgg ttggtaagat ctaaaaagaa
     9001 tgatgtgcca attgattaat gtgccaatat gccaattatt tatgaggcaa tacatcgctt
     9061 tagtcgattg gtacattctt taattggcac gttaataaat tgacatatta tttttatgtt
     9121 agactcagca atgaaagacc agctttcggg tattttctcc ggactggtat cccaatatgt
     9181 atttgatata caagtcgctc ccgatcacga aagccgtcag gagctaatag acctgcttgg
     9241 tgatgtggca tcatgctcgg atcatttgtc atgcagcgtt gcggatggcg aaggacttca
     9301 gtttacaatt gtaaaagacg gtatgcctac cggtatccgg tttcgtgcag tacctaacgg
     9361 acatgagttt acatccttgt tgttagctgt cctgaatagt gatggaaaag gtaaaaatat
     9421 accggacgaa agtatctgtg ctcgtgtcag agccttgaat ggtccgatca agctgacgac
     9481 ttatgtttct cttacttgca ccaattgtcc ggatgtagtg caggcactca atgtcatggc
     9541 tactctcaat agccggatca cccacgaaac ggtggatggc gctatcaacc aaaaagaagt
     9601 tgaggcaatg aaagtacagg gggtcccttc tgtttttgcc gatggcaaac tgatcaatgt
     9661 ggggcgtagt gatttgggag aattgctttc caaactcgaa gcccaatacg gaattaatga
     9721 agggggtgtt gataactctg ttgaaaaacc tgttaagaac tatgatgtgt taatagtggg
     9781 gggtggacct gccggtgctg cttctgctat ctactcggca cgtaaaggct tgaatgttgc
     9841 tgtgatagcc gaacgtatcg gaggacaggt caaagaaacg gtcggtatcg agaacctgat
     9901 ttccgttcct cagactactg gaaagcagtt ggcgaacgac cttctgatgc acatcaacga
     9961 ctatccggtc gatatactgg agcatcgccg tgtggataaa gtcgaactgg atggatcggc
    10021 gaaatttctg accacttcta ccggtgaacg tttttctgct cctgccctta tcgtggcgac
    10081 aggtgcaagc tggcgcaagt tgaatgttcc gggcgaagcg gactatatcg gaaaaggtgt
    10141 cgctttttgc cctcactgcg atggtccgtt ctataaaggt aagcacgtag cggttgtcgg
    10201 cggtggaaat tcgggtatcg aagcggctat agatttggca ggcatttgtt cgaaagtgac
    10261 ggttctggaa tttatggacg aactgaaagc cgaccaagtg ttgcaggaaa aagcaaagag
    10321 cttgccgaat gtagaagttt tcttgcattc ccaatctttg gaagtggttg gtgacggtga
    10381 taaggtaaca ggtcttcgtg taaaagaccg taagacggat gcggagcggg tgattgacct
    10441 ggacggaatc tttgtccaaa tcggcttggc agccaatagt ggcgttttcc gcgatgttgt
    10501 cgaaacgaac aaaccgggtg agattgtaat cgatgcgcat tgtcggacga atgttcccgg
    10561 catctatgcg gcgggcgacg tctcgaccgt accctataaa cagataatca tagcaatggg
    10621 agaaggggca aaagcggctc tatctgcttt tgaagaccgc atgagaggtt taatcggtta
    10681 atatttagta tttgctatga acgacgaagg tgtgcaatat tgaactgcat gaatgtatgt
    10741 tcaaaattgc acaccttttc tttttttacg cacaaagccc cgactttcac aacagggcaa
    10801 ccgcatcaaa attttccaag gttgtgatct ccatacgaag ttttctacaa atcctctatc
    10861 actctatcac tacgaaggtt gtagctatta atattcaagc gttagaggag tgatagagga
    10921 aaacatcctg tatcactgcc tctatcactc ctgaaacagg acgtttttat catatgattg
    10981 gaaatcaatg tattgccttc atttgctttt gaaaaagcat ataaaataat cgaataaaca
    11041 aatgtaaaaa cgaatgcaat aggtgttaaa ttggcgaaat acggttcttc attccacaaa
    11101 agccctctct ttttttagca aagacaagca cataatttcg taaacacccc catgttgcca
    11161 tccttaacat ccgggtgtag agaactggta cacccgggtg taagaggggg caacatgggg
    11221 gtgtccggca actaaagtac cgtgccggac aatgaaaacc acccggtttt acctatttta
    11281 tagccgtttt tacataaaat aatcgagtga tttataggga tggaaattgg gtgtttattg
    11341 tttgtgttat ttataatacg ctaatctaca gatgtgtata agcgtaattc ctgtttccca
    11401 tctaaattgc cagtgatagg gtagtgatac cgtagtgata gagaaaacgg gcatatatca
    11461 ctaacgaaac agcttgaata tcaatcgata aaaaagaaat cagtgataca gtgacagagg
    11521 aaatgggaaa aacttgtatg ataaggccct gtttttttct ttggtatatt ttatacgatt
    11581 tctgaatttt agtgcagttg ccctgcaaaa tggcgtatcg ttcattacga cacactttct
    11641 tttattttat ggataatttt tcttcttttt gccacctaaa ggccgttttt aactccattt
    11701 tcccagcctt cttctcaaaa tggcagtttg ttactgcagt attacttgag taaaagttta
    11761 taagtgatta taaataagga tgatatgtct gtttgtgaag aacagtaaaa aagcccgttt
    11821 tcaaggggtg aaagttactt gtttttactt gtaacttatt gggaataaaa aagatagtag
    11881 tcagaaacaa aatgactaaa aaaacgttcg ttttaattcg tcatttttac tgcacaaaaa
    11941 tacaactact ttttgaacct gcaatccttt ccacaaatat tttttctttt tctatattct
    12001 ttcttatcaa tcagatagct taaggagtac gaaaaaccgc ctttccgata caaactcttt
    12061 cgaagaccgc ccaaaatgac taaaaaaaac gaacgttttc gctatcaaag tacaaaagtt
    12121 aacagatagt cttgcgtaca ttaaatatat aaaagaagaa attattctta atacattatt
    12181 tactaacaaa ttaatttaag ttatgaacaa aaagttttct actcttgtcg ccagtatgtt
    12241 actggcaacg acagtcggaa cagtttctgc acagaaccta gagttcacaa agtcagctct
    12301 acctacaaat gttagggtag agagtgtggc cgacggaaaa tgctatcagt tgacagacgg
    12361 ttggaatgtg ttggtaatgc agaaggtttc gacagaaaaa ggtgatcgtt tcatcttgaa
    12421 gtatgtccct tattacgcag ccaatatagg ggaatccttg tggtatgtga cggttgataa
    12481 agacaataag gaaaatggtg tggcctttaa atttatgaac ttggcttata attatcctat
    12541 ctcttttgat ccggcaaaga ttcaggatta taaaccggga aagacttatg aaggttctta
    12601 tttggctggt gaagcagtcg cttgggcttg gatgagaagt gaagccggtg agggcttaaa
    12661 tgtaggtaaa actccggaag cctatttcaa gacagactct gtgatgactt tgattccgaa
    12721 tgcagatggt acggttgctg ctgtcaaata tgatgttcgt gagactgaca agcttgcaca
    12781 gttgaacatt cgtccggctg ttgctggtcc tgtttggtta ggaaagaacg atttgaacag
    12841 catgttgcag acacaagatg caacaaatgg taaaacatct ttctcttttg aaaaagatgt
    12901 gacagaaggt ttggcaaact tgtggtctgc aggtaaaggc catgcttatg aggctgttga
    12961 tgctgtaggc gaaagcactt tgtcatatgg tgctgttgct gatgctgctg ctgaaaagga
    13021 tgcggctatg cttgctgcca atgaagctga aaaaaaagta gaagcagccg tgaaagctct
    13081 ggctgatgct gaatcagaat attatgtttt ggctcagaag atccagaatg tagagtctga
    13141 aaaggttgaa aaaggtagag aacttgtgaa tcaaagttgg atttacaact ttttgaatga
    13201 aagtgaagat gttacaaaac aagcgatttt acagaaaaaa caatctatcg caacaagttc
    13261 tgctctaaac gaagaggcca agaaacaact tgcagaattg gctgaaaaat tagaggcagc
    13321 tcaaaatgaa tataaagatg cagttgctgc ccagaccgct cttcaaaatt ctatcaataa
    13381 tgccacggat gcatggattg ttgctctgga tgttaaaaat aaagcagtcg atcagaaaag
    13441 tagatatgca aagtggggaa cagcgatgag gaagtatttc aacgaaacaa gtgatgtaca
    13501 ttatgtctca gatatgggct atgcccctaa tgataaacca caagcatgga attcttattt
    13561 cgatgcagct aaggtaattg atgaagcaga gaaggaagcc tttgtagaat atggacatcg
    13621 tttgtatgct atcttgaaag aagcaaataa tggtgtagat atatcaatgt ctgcttcagc
    13681 ttataagaac caaaacgata aggcttttac aaatggtgtc aatgctctta atactgaaga
    13741 agatgaaacc gttgaaaaag ctgcagaagc tgttatcgct tcagaaggtg caatagcttc
    13801 aatctctaaa gatttaggtg ttgctattgg tgtagcagag gagaaaaagc aagctgagaa
    13861 ggctgccagc acagcttatg acgaaatgtt taaagcttat ggagttcaca gtcaagctct
    13921 tgaagaagca gagaaagagt tgaaagaact tgaagaagaa ttggcctctg ttcaagctga
    13981 actgaaagaa gttagtgcta agaaggtcga gctagaaact gctattttca actatacgca
    14041 acaaattgca agtttgaatg aacagttgat ggctttagat ggtgaaaagg gggcagctta
    14101 ttggacatgg gtagacgctc gttatgcgca taaggatgct gaacgtgctg ctatcaaggc
    14161 ttcagaagtg tttgaaaaca ttcgtcttga aaagtcattt aactggttat ctctgaaagc
    14221 cggcaagaat gccaagggcc aggatactta tttaatggtc gacacagctt atctgaacgg
    14281 ctcagccggt gaagaaattg caggtatcca gcatttagga ttcgctactc gtgaacatga
    14341 agctgatttc aaatctgtca acaacttggc agctcgcgat atcaacggtc gcttcaactt
    14401 ccgtttcttc tactggccga ctcaggactc tttgcgtatt gaagcagatg gttacaacgt
    14461 gaagaacgta acgactaagt attggaagga tcgtacaaat agtgaaatcg atatttttgc
    14521 tacttctgca aaaggccaag aaaacaatct ggttaagatt gccgtattag gtggtgcccg
    14581 tcgtgaagcc actatcggtt cttccgaaga gctgaaaggc acaggtatct atacatacaa
    14641 cgaccgtatc ggtttgagcc tctctcctgc tgctcacaat gccgttttgg aaccgggcat
    14701 ctatttcatg gatgtagtaa atggtgctga tgcacagaag aacggtgctc gcttgatggg
    14761 tgatttgaac ggctggaact tgactaaggt tgctccggct gaatgggatg tgatgaactt
    14821 cgaacacatg ccggccgcta agtgggttgt aaatcagaat acgaatgaat tcggtggata
    14881 tcctgaaatt tggaaccaag aaacaggagc tactctgaat aatggttctt acaaagtatt
    14941 ggctgatggt aatatcgtaa ttaactatta ttataacaac gaagaagctt ggttggctaa
    15001 tgatacgctg aaattgacaa agaccgtaag taaccgattg ggcttcttta acgatgatgc
    15061 caagaatgta aactatactt tgaactactt gaatgtaggc aatgacttgg gtgttacaat
    15121 tggtaactct accgtaggta atgacacgat cctgcgtgta tctgccgatg aggctactaa
    15181 gttcgaattg gtaaaatcgg gcagtagtta taatacccct atcttcgaaa aagacacgat
    15241 cttccagact tattatcaga tccgtgtaaa cgatccgtat aagttcgcta acaaccagaa
    15301 atatgttcag gtatctgaag ttggtggtac tgaaatgatg gtagtaacag aaggtgcaga
    15361 aaatggttct gtattcactt tgaaagaagt gaactgcgta gacggaactc attactatgc
    15421 attgctgaca gaaggcaaga aagccggtgt gattgatgca acaggcttga ttaaggctga
    15481 aaacgtggct actgaatcta caacttctgc tttcgcattg gttgctgata cgactgctct
    15541 gtatcgtgag tttacagctg acgaattggg tgaaaacggc gcaatgaagt tctaccgtgt
    15601 gaactctact gctaaggctt acttgtatga aggagctgac aacctgcttt gcgtagaagg
    15661 taagggtgac gataaagctg aagcattcaa tgtaatcccg acaggtgtcg aaaacacatt
    15721 gatgccacag tacttgattg ccaaggatgt gaactttgta gtcggtgata cagttctgtg
    15781 cgacgctact actcactctc atgcaacaat agaagaagct ttgaaatgcc cgcatagtaa
    15841 agtaactgct gacacgacat ttggtcgttt cttggtgaac atgatcgact cagttcccgc
    15901 tgttaagaaa tatacttggg aaggtaaata caagagactt gcattcttgc cgggttatat
    15961 gacagctggt aacttagttc tggatggtac aactcataaa gtcgctctga agctgaatgc
    16021 tcatgatcag gctaagttct ctttccgttt ggttaacgaa ggatctaacg acttcttgat
    16081 cgaatctgaa tcttatggaa agaagacagc gtttgatggc ggtatcgctc cgtctgctaa
    16141 tctgggtggt tgggtgaaag tacagaacgg tgttcctgtc atcatcaatg acttcgaagc
    16201 agctatgcag tctgacctct acaatgtcga cactaacgct ggtggtgcaa cagccaacga
    16261 cgaaatcacg acttctgaag taacgattat cgcaggcgaa ggcaatgtta caatcgctaa
    16321 tgctgccggc aagaaggttg ttgtaagcaa catcttgggt caggtagtag ccactcaggt
    16381 tctgacatcc gacaatgctg tgattgctgc tcctcaaggc gtagttgtag tagctgttga
    16441 aggtgaagaa gctgtaaagg caatcgtgag ataaggatag aggaatagtg atagtattgg
    16501 agtggcagca gccactccct ctatatagta atttataatc aaataattct aaaatgtttg
    16561 gccgcgtgcc gtgcaaacgg taattaccct gtgacaggcg aacaagcggt ttaatattaa
    16621 taatactaaa gtattgaaat aaagttcatt ctgctgtgag cctgtgaagg tgtaaggcag
    16681 ataaaaaaca agccccgggg acggtttcgt cttcggggct ttgttttcaa cttttttaca
    16741 aaggcttttc cggatacatg gcattccacc attccggttg gttcttgagc catttggcga
    16801 accaagcgta gatggtttta ttccattcgg cacgcttctt atagtccagt atctggtggt
    16861 tttgtcctac tacttgtacg aaggccgtag gtttgcctaa cagtttcagg gctgtaaaca
    16921 tctggatgct ttcacctacc gggacgttcg tgtcgacagt gccatgcagg aaaaggatcg
    16981 gggtgttgat tttgtcggca ttgaacagcg ggctttgcaa cgtgtacata tcccgtgcgt
    17041 tccagggata gctgtttgcg cttgccaaag cactatagga gtatccccag taaccttcgc
    17101 cccaatagct ggtgatgtcg ctgattccgg catgagagat ggcggcggca aagatatccg
    17161 tttttgtttg caggtattgt gtcatgaagc caccgtagga tgcccctatg caaccgatct
    17221 ttttagcgtc gacaaagttg tgttcggcac agaatttctt tgttccttcg atgatctcgt
    17281 ctcctgtacg ttgtccccat gcatttacgt ggcgggcgga gaactcctgg ccgaagccgg
    17341 ttgctccgct gggctggatg atataaacga tgtagcccaa tgccgcatat acgtgcgacg
    17401 gataccggtt ttctagtgaa cgttccgtcg gactggttcc cccgtagtag ttcacgatca
    17461 gcggatattt cttgttagga tcgaaatggg gcggcaggta ataacgaccg tagatcgtgt
    17521 cgccggcagc tgcccggaaa ttccaatcgt gcacttcgcc gagggtgata tctttcaaga
    17581 tgccggcgga aagatctttc agacagacag aacttttctt tttcaggttg acggaataga
    17641 ggcgttgcga gttggaggcg ctttcgccga aataaaccag ttcgggagtt gtttcggcaa
    17701 tcgtaaaatc cgagaggata tcctctttta acgggatggg gaggattttc ccggttgacg
    17761 gattcaagac gtacaggcgt atgcaatcct tatcttctcc ctgcaggtag atctgtttat
    17821 cacctttgtt ccaaacgaag tttt
//
