LOCUS       gnlProkkaFFFDHAFJ_78    7861 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FFFDHAFJ_78.
ACCESSION   gnlProkkaFFFDHAFJ_78
VERSION     gnlProkkaFFFDHAFJ_78
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-18 11:36:16
            Original ID  :: gnl|Prokka|FFFDHAFJ_78
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 7861
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..7861
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[140:6541]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      141..6541
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..7861
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..7861
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             complement(2..151)
                     /locus_tag="ctg78_1"
                     /transl_table=11
                     /translation="MDGSLSLSASLIKIKLSDICAILGCEYMGEDFLVDGFNLSNRKIE
                     SQCVI"
     CDS             complement(141..1229)
                     /NRPS_PKS="Domain: Aminotran_5 (36-196). E-value: 6.4e-09.
                     Score: 27.0. Matches aSDomain:
                     nrpspksdomains_ctg78_2_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056:DegT/DnrJ/EryC1/StrS aminotransferase (Score:
                     265.1; E-value: 1.7e-80)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg78_2"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 5e-84, bitscore:
                     271.6, seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_5 (E-value: 4.2e-08, bitscore:
                     21.5, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIPLVKPYIPDRKVLMPELENVLYSGYIAEGQPVYDFEKQFQTFI
                     GNPYCLALHSGTDALHLALLLAGVGIGDEVISTPMTAEPTNVAITMVGAKVVWGDVHPA
                     TGLLDPDSVRSQITSKTKAIIVVHYAGMVCDMTRFNQISKEFNIPVIEDAAHALGSKFD
                     GQYVGCNSDYTIFSLQAIKHMTTVDGGFLALKSQENMDKARIKRWFGLDKTKSRLENDI
                     KETGYKYSMNNVNATIGLVQMRFLRSVLDKYISNGKFYDNSLQNIDGLQLIPYYDKTEP
                     SYWLYTMKVDHRDDFVKMLESNEIMASPLHHRNDTHSLFSTSRRILPGLEDFYGKLVHI
                     PCGWWVTEKDRLKIVDCIKNGW"
     aSDomain        complement(642..1121)
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg78_2_Aminotran_5.1"
                     /evalue="6.40E-09"
                     /label="ctg78_2_Aminotran_5.1"
                     /locus_tag="ctg78_2"
                     /protein_end="196"
                     /protein_start="36"
                     /score="27.0"
                     /tool="antismash"
                     /translation="FEKQFQTFIGNPYCLALHSGTDALHLALLLAGVGIGDEVISTPMT
                     AEPTNVAITMVGAKVVWGDVHPATGLLDPDSVRSQITSKTKAIIVVHYAGMVCDMTRFN
                     QISKEFNIPVIEDAAHALGSKFDGQYVGCNSDYTIFSLQAIKHMTTVDGGFLALKS"
     CDS             complement(1241..2251)
                     /NRPS_PKS="Domain: NAD_binding_4 (8-139). E-value: 3.6e-08.
                     Score: 24.6. Matches aSDomain:
                     nrpspksdomains_ctg78_3_NAD_binding_4.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score: 99.1;
                     E-value: 5.3e-30)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg78_3"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 2.1e-105,
                     bitscore: 341.1, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="RmlD_sub_bind (E-value: 1.4e-10, bitscore:
                     29.8, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFKDKVLMITGGTGSFGNAVLKHFINSDLKEIRIFSRDEKKQEDM
                     RIEYKNDKLNFIIGNVRDFDSINNAMAGVDYVFHAAALKQVPSCEFYPMQAIRTNLYGA
                     ENVLEAAARNNVKKVVVLSTDKAAYPINAMGMTKALMEKLAISKARDARVEANNGIICA
                     TRYGNVMCSRGSIIPLFIKQIKEGLPLTVTEPRMTRFMMSLDDAVDLVLFAFQNAEPGD
                     LFVQKAPAATIHDLAIAVKEIFNANNEIRIIGPRHGEKMYETLCTKEEMSKATDMGSFY
                     RIPADFRDLNYTKYLQKDGPRLVDHEYNSENTQRLSLDELKNLLLSLDYVQNELK"
     aSDomain        complement(1835..2227)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg78_3_NAD_binding_4.1"
                     /evalue="3.60E-08"
                     /label="ctg78_3_NAD_binding_4.1"
                     /locus_tag="ctg78_3"
                     /protein_end="139"
                     /protein_start="8"
                     /score="24.6"
                     /tool="antismash"
                     /translation="ITGGTGSFGNAVLKHFINSDLKEIRIFSRDEKKQEDMRIEYKNDK
                     LNFIIGNVRDFDSINNAMAGVDYVFHAAALKQVPSCEFYPMQAIRTNLYGAENVLEAAA
                     RNNVKKVVVLSTDKAAYPINAMGMTKA"
     CDS             complement(2268..3377)
                     /NRPS_PKS="Domain: Aminotran_5 (30-298). E-value: 6.3e-34.
                     Score: 109.3. Matches aSDomain:
                     nrpspksdomains_ctg78_4_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 80.5; E-value:
                     1.9e-24)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg78_4"
                     /sec_met_domain="Aminotran_5 (E-value: 6.3e-32, bitscore:
                     99.9, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIERKILLNPGPATTTDTVKLAQVVPDICPREKEFAGMMKQLRD
                     DLVRVAHGDLSKHTAVLFCGSGTINIDICLNSLLPADKKVLVVNNGAYSTRAVEVCEYY
                     GLPHIDLKFSVYELPDLSVIEKTLSDNPDIALVYTTHHETGTGILNPIREIGKIAHSHG
                     AVFVVDTTSSLGMIPFDIGKDNVDFCMASAQKGLQAMTGLSFIIGDESLIRASRDYPKR
                     SYYCNLYLQYDYFEKTGEMHFTPPVQTVYAARQALDEYFAVGEEAKFARHKRVFEAIHK
                     GLQELGLQYAIKREWQSGLVVSVLYPDDPLWDFDKVHDYCYERGFTIYPGKISTTNTFR
                     LCALGEIDVEDIERFFEVMREAKMSLNNK"
     aSDomain        complement(2484..3287)
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg78_4_Aminotran_5.1"
                     /evalue="6.30E-34"
                     /label="ctg78_4_Aminotran_5.1"
                     /locus_tag="ctg78_4"
                     /protein_end="298"
                     /protein_start="30"
                     /score="109.3"
                     /tool="antismash"
                     /translation="PREKEFAGMMKQLRDDLVRVAHGDLSKHTAVLFCGSGTINIDICL
                     NSLLPADKKVLVVNNGAYSTRAVEVCEYYGLPHIDLKFSVYELPDLSVIEKTLSDNPDI
                     ALVYTTHHETGTGILNPIREIGKIAHSHGAVFVVDTTSSLGMIPFDIGKDNVDFCMASA
                     QKGLQAMTGLSFIIGDESLIRASRDYPKRSYYCNLYLQYDYFEKTGEMHFTPPVQTVYA
                     ARQALDEYFAVGEEAKFARHKRVFEAIHKGLQELGLQYAIKREWQS"
     CDS             complement(3374..4510)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 71.8;
                     E-value: 7.9e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg78_5"
                     /sec_met_domain="TPP_enzyme_N (E-value: 1.2e-22, bitscore:
                     69.4, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 3.2e-21, bitscore:
                     64.8, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVSVEKIYDTFLHHGVDFFTGVPDSLLKNICAYITDHAPRGKHII
                     AANEGSAVGIACGYYMASGNVPLVYMQNSGLGNTVNPLLSLADEKVYSLPLLLLVGWRG
                     EPGTKDEPQHKKQGEVTLDLLKAMKIPFIILDTDEDEALAQIHDAVVSAKSRSIPHAIV
                     IRKDTFGKYKLRQEALNDYPLSREEALMQVVDHLGDNDIVVSTTGKLSRELFEYRESKG
                     QGHARDFLTVGSMGHSSSIALGVALEKPDRRVYCLDGDGAFIMHMGAVSNIGDLSPKNY
                     RHVLFNNGAHESVGGQPTLGFRLDIASIAKGCGYAHVLTASDKEGLSCALEKLSGLSGP
                     VLLEIKVRIDSRDDLGRPTTTPVENKEHFMAFLKDTHS"
     CDS             complement(4522..5823)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 214.1;
                     E-value: 3.9e-65)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg78_6"
                     /sec_met_domain="CTP_transf_like (E-value: 2e-13, bitscore:
                     39.9, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 7.4e-123, bitscore:
                     398.2, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 3.7e-65, bitscore:
                     208.8, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKIYVGMTADIMHPGLIHIIHEATKYGDVIVGLLTDKAIAEHK
                     RLPYLTYDQRKEVVENIKGVCEVVPQEDWSYVPNLEKLKPDYIIHGDDWKTGPLREVRE
                     QVFEVMNAQGGKVIEIPYTRGINSSSLDKDIKAIGTTPDVRLKSLRRLIQAKPVVRILE
                     AHDGLCGLIIENLEVQKGDKREVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAVIIEDKVGLKKNSLFGTDAIQTQDS
                     IEGFCDKIRAGKNAQVTGDFMIIARIESLIAGKPMSDALERAYAYVQAGADGIMIHSKD
                     KSGEDIREFCRTFRKEYAHVPIVVVPTTYDHVHESELHEWGANVVIYANHLLRAAYPAM
                     MNVARTILENERAEEVRPLCMPIKEILELIPGTK"
     CDS             complement(5843..6541)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg78_7"
                     /sec_met_domain="NTP_transf_3 (E-value: 2.1e-14, bitscore:
                     43.3, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAGLGTRFGHYTELVPKGFVEVGGKPMIIRSIETLLSCGIERII
                     LGTGYKKEAYEALQADFPQIETCFSPRYADTNSMYTLYNTRDVIGDDSFLLLESDLVFE
                     RKAILPLLDDEFPDVMLVSSLTKFQDQYYVEYDRNHILTSCSVDKNSLEAKGELVGIHK
                     LSNTFYRRMCADYATILESQPKLGYEYELLRMSRSVSPVRVLRVEGLKWYEIDDEADLS
                     YAEEHIIRYC"
     CDS             complement(6555..7859)
                     /locus_tag="ctg78_8"
                     /transl_table=11
                     /translation="MVQRTTRMIRSFLSRSPLYVLALYASVLIFLVYTCAYAYRKPFTA
                     AIYEGEILWGFDVKILYVLSEIIGYALSKFIGVRILPSMKAGHRIYYIIGLLTFSEVAL
                     LGFALLPVPLKVCSIFLSGLPLGMIWGVIFSYIEGRRISEILNVGLSVALIVSSGLVKT
                     LGQFVMDNLHVSEYWMPFTTGLLVYPVMLLCSWLLNQIPAPNEQDIIQRTKRAPMDGKD
                     RRKFLRQFFWGICMLVVFYGALTVFRELRDSFAADIWKELHIEGAMIFTQTEVPIAVFV
                     LVLMFLIVFVRNNRLALNIIYCIAVTGGSLMVFSTLLYVYGFLSPIWWMILSGLGLYMG
                     YIPFTYLIERLIASLRVVSTAVFIIYLADSFGYLGTTGVFMVKNFVSADISWTVMLMRT
                     ALFSGFVSVLSIFAIYCYFKQQLNSLILIPSEIHD"
ORIGIN
        1 atataacaca ttgagattct attttcctat tactcaaatt aaatccatca actaaaaagt
       61 cctctcccat atattcacaa cctaatatgg cacagatatc tgacagtttt atttttatca
      121 aacttgcaga taatgataag ctaccatcca ttttttatac aatctacaat tttaagtcta
      181 tctttttctg ttacccacca accacaaggt atatgtacta acttaccata aaagtcttct
      241 aaacctggca aaatccttct tgatgtagaa aaaagactat gtgtatcatt acgatggtgc
      301 aaaggtgaag ccattatttc atttgactcc agcattttta caaaatcatc tcgatgatca
      361 actttcatcg tataaagcca ataagaaggt tcagttttat cataataggg aattaactgt
      421 aaaccatcta tattttgcag agagttatca taaaactttc cattactgat atatttatca
      481 agcacagacc gtaagaaacg catttgaacc agccctatag tagcattcac attattcata
      541 ctatatttat aaccagtttc cttgatatca ttttccaaac gggatttagt tttatccaac
      601 ccaaaccaac gcttaattct agccttatcc atattttcct gtgactttaa agctaaaaag
      661 ccaccatcaa cggtagtcat atgtttaata gcctgtaaag agaatatcgt ataatccgag
      721 ttacagccga catattgacc atcaaattta ctccctaagg catgagcggc atcctctata
      781 acaggtatat taaactcttt cgatatctga ttaaaacgag tcatatcaca taccatacca
      841 gcataatgaa ctacaataat agcctttgtt tttgaagtta tctgagaacg gacagaatca
      901 ggatctaaca aacctgtagc tgggtgaaca tccccccaaa caaccttcgc tccaaccata
      961 gtaattgcga catttgtagg ctcagcagtc ataggagtac tgattacctc atcacctatg
     1021 cctacaccag ccaaaagtaa tgccaaatgt aacgcatctg ttcctgaatg taacgccaaa
     1081 caataaggat tgcctataaa agtctggaat tgcttttcaa agtcataaac aggttgtcct
     1141 tctgctatat aaccactata cagaacattt tccaactctg gcattaacac tttccgatca
     1201 ggaatatagg gtttaaccaa tggtatcata atggtattat ttatttcagt tcattttgta
     1261 cataatcaag acttaacaaa agatttttaa gctcatctag gcttaaacgt tgagtatttt
     1321 ccgaattata ctcatgatca accaagcgtg gtccatcctt ttgcaaatat ttggtataat
     1381 ttaaatcacg aaaatctgca gggatacgat aaaatgaacc catatctgtg gccttagaca
     1441 tctcctcttt cgtacaaaga gtttcataca tcttctcgcc atgccgtggt ccaataatcc
     1501 gaatctcatt atttgcatta aatatttcct tgacagctat tgcgaggtca tgaatagtag
     1561 cagccggtgc tttctgaaca aataaatcac ccggttctgc attctgaaat gcaaaaagga
     1621 ctaaatctac tgcatcatct aaagacatca taaaacgagt cattcttggc tctgtaacag
     1681 tcaatggtaa accttctttt atctgtttta taaataaagg tataatagaa ccacgagaac
     1741 acattacatt tccataacga gtggcgcaga ttataccatt attagcttct acacgagcat
     1801 cccttgcttt agatatagcc aacttttcca ttaaggcttt tgtcattccc atagcattta
     1861 taggataagc agccttatcg gtactcaaaa caacaacttt tttaacatta ttacgagcag
     1921 cagcctccaa tacattctca gcgccataca agttagtacg aatagcctgc attggataaa
     1981 attcacaaga aggtacttgt tttaatgcag cagcatggaa aacataatca acgcctgcca
     2041 ttgcattgtt aatactatca aaatcacgca cattaccgat aatgaaattt aatttatcgt
     2101 ttttatattc aatgcgcatg tcttcctgct tcttttcatc acgactgaat attctgattt
     2161 cttttaaatc agaattaata aaatgtttta aaacagcatt accaaaagag cctgttcccc
     2221 cagtaatcat tagaacttta tctttaaaca tatatcatac tattatccta tttattattc
     2281 aaactcattt tcgcctccct catcacctca aagaacctct caatatcctc cacatcaatc
     2341 tctcccaacg cacaaagccg gaatgtattc gttgtggaaa tcttacccgg gtagatcgta
     2401 aagccacgtt catagcagta atcatgaacc ttatcaaaat cccagagggg atcatcagga
     2461 tacaatacag aaacaacaag acccgactgc cattcacgtt tgatcgcata ctgaagacca
     2521 agctcttgca aacctttatg gatggcttca aagaccctct tgtgacgggc gaatttagcc
     2581 tcttcaccta ctgcaaaata ttcatcaaga gcctgacggg cagcgtaaac ggtttgaaca
     2641 ggaggagtaa aatgcatctc acccgtcttc tcaaagtaat cgtattgtaa atagaggtta
     2701 caatagtagg agcgtttcgg ataatccctt gaagcacgta tcagggattc atcacctatg
     2761 ataaaggaaa gacccgtcat ggcctgaagg cctttctgag ccgaagccat acaaaagtca
     2821 acattatcct tcccgatatc aaaaggaatc atacccaggg aggaagtggt gtcgacaaca
     2881 aaaacggcac cgtgcgaatg ggctattttt ccgatctcac ggatggggtt caagataccc
     2941 gtacccgttt catggtgcgt ggtatagacc aaagcgatgt ccggattgtc ggaaagcgtc
     3001 ttttcgatta ccgacaggtc gggaagttcg taaacggaaa acttcaaatc gatatgggga
     3061 agaccgtaat attcgcagac ttccaccgca cgggtgctat aggcaccgtt attgacaacc
     3121 agaactttct tatccgcagg aagaagagag ttcaggcaga tatcgatatt gatcgtaccc
     3181 gagccgcaaa acaggacggc cgtatgtttg gagaggtctc catgcgcaac gcggaccagg
     3241 tcgtcacgta actgtttcat catacccgca aactctttct cacgcggaca gatatcggga
     3301 acaacctgcg ccagctttac cgtatccgtc gtggtggcgg gacccggatt caaaaggatc
     3361 tttctttcga tattcatgaa tgcgtatctt ttaaaaatgc cataaaatgc tctttattct
     3421 ctaccggagt agtcgtaggg cgacccagat catcacgtga atcgatccgg accttaattt
     3481 caagaagaac cgggccggac aggccggaca gcttctcaag cgcacacgaa agcccttcct
     3541 tgtcggaggc agtcagtaca tgcgcataac cgcaaccttt cgctatcgag gcgatatcca
     3601 gacggaaacc gagcgtgggt tgaccgccga cagattcatg ggcaccgttg ttgaaaagga
     3661 cgtgcctgta attcttggga gaaagatcgc cgatattgct gacagcaccc atgtgcatga
     3721 taaaggcacc gtcaccgtca agacagtaga cacggcggtc aggcttctca agggcaaccc
     3781 ccagggcaat ggaagaactg tgccccatgg aacccacagt taggaaatcc cttgcgtgcc
     3841 cctgcccttt cgattcacgg tactcgaaaa gctcacggga gagcttgccc gtggtggaaa
     3901 ccacaatgtc attgtccccg aggtggtcga caacctgcat tagcgcctcc tcgcgggaca
     3961 gaggatagtc attcaaggct tcctgacgca atttatattt tccaaacgta tctttacgga
     4021 tgacaatcgc atggggaatc gaccggctct tcgccgagac aaccgcgtca tggatctgcg
     4081 ccagggcctc gtcttcatcc gtatccagaa ttataaaagg aattttcatg gctttcagaa
     4141 gatcaagggt aacctcgccc tgcttcttat gctggggttc gtctttcgtg ccgggctcac
     4201 cgcgccagcc gaccagcaaa agaagaggaa ggctgtacac tttctcgtcc gcaagggaca
     4261 agaggggatt caccgtattt cccagaccgg agttctgcat ataaaccaaa ggaacgttgc
     4321 cagaagccat ataataaccg caggcaatgc ccaccgcgga accttcattg gcggcgatga
     4381 tatgcttacc acgcggagca tgatccgtga tataggcgca aatattcttc aaaagggaat
     4441 cgggaacacc cgtaaagaag tcaacaccgt gatgaaggaa cgtatcgtat atcttttcta
     4501 cacttaccat aaccgtctga tttatttagt gcccggaatc aattccagaa tttccttgat
     4561 aggcatacaa agcggacgga cctcctcggc gcgctcgttt tcaaggatgg tcctggccac
     4621 gttcatcatg gccgggtaag cggcacggag aaggtggttg gcgtaaatga ctacgttggc
     4681 accccattcg tgaagttcgg attcgtgcac atggtcataa gtcgtcggaa caacgacaat
     4741 gggaacatgg gcgtattctt tgcggaaagt ccggcagaac tcacggatat cctcacccga
     4801 cttatccttg ctgtggatca tgatgccgtc cgcacccgcc tgtacatagg cataagcacg
     4861 ttcgagggcg tcactcatgg gtttgccggc aataaggctt tcgatacgcg caatgatcat
     4921 aaagtcaccg gtgacctggg cattcttccc tgctctgatc ttatcgcaga aaccctcgat
     4981 actatcctga gtctggatag cgtcagtacc aaaaagggaa ttcttcttca gaccgacttt
     5041 atcttcaatg attaccgcag aaatgccgtg acgttccaga gtgcgcacag taaagacaaa
     5101 gtgttcgatc ttgccacccg tgtctccatc aaaaataata ggcttggtgg tgcattcaag
     5161 gatattgttc aggtcctgta aacgggtggt aaggtcgacc gcttcaatat ccggtttacc
     5221 cttactcgtg gagtcggtca ggctgctgga ccacatgccg tcaaagacct cgcgcttatc
     5281 acccttctgg acttcaagat tctcaataat cagaccgcaa agaccgtcgt gagcctccag
     5341 gatacggacc acaggcttgg cctggatcag gcggcggagg gacttaagac gtacgtcagg
     5401 ggtagtcccg atcgccttga tatccttgtc gagcgaggag gagttgatgc cccgggtata
     5461 agggatctcg attaccttgc ccccctgggc gttcatcacc tcaaaaacct gttcgcgcac
     5521 ctcgcgcaac gggcccgttt tccagtcgtc gccgtggatg atatagtcag gcttgagttt
     5581 ttccagattc ggaacatagc tccagtcctc ctggggaaca acttcgcaaa cccccttgat
     5641 attctcaaca acctccttac gctgatcata ggtaaggtaa gggaggcgtt tgtgttcggc
     5701 gatggccttg tccgtcagca gaccgacgat gacatcaccg tatttagtag cttcatgaat
     5761 aatatggatc agccccggat gcatgatatc cgcggtcata ccgacataga ttttcttgtt
     5821 catatatgga aaagatttgt ttttaacaat agcggatgat gtgctcctcg gcatacgaaa
     5881 ggtcggcttc atcatcgatt tcataccatt taagaccctc caccctgagc acacggacag
     5941 gagaaacgga acgggacatg cggagcagtt cgtactcgta acccagttta ggctgggact
     6001 ccaggatggt cgcataatcg gcgcacatcc ggcggtagaa agtattggaa agtttatgga
     6061 taccgaccag ctcgcctttt gcctcaaggg agttcttgtc taccgaacag gaagtaagga
     6121 tgtgattgcg gtcatattcc acataatact gatcctggaa cttggtcaga gaagagacaa
     6181 gcatcacatc cgggaattcg tcatccagta gcgggaggat ggccttgcgt tcaaaaacaa
     6241 ggtccgattc aagcagcagg aaactgtcat cgcctatcac gtcacgcgta ttgtacagag
     6301 tgtacatact gttagtatcg gcataacggg gactgaaaca ggtctctatc tgggggaaat
     6361 ccgcctgaag ggcttcataa gcctcttttt tataacccgt accgaggatg atacgttcga
     6421 taccgcagga aagaagggtt tcgatagagc ggataatcat aggttttcca ccaacctcca
     6481 caaaaccttt gggcacaagc tcggtataat gcccgaagcg ggtaccaaga ccggcagcca
     6541 tgatcattgc tgttttaatc atgaatttca gagggaatta atataagtga attcaattgt
     6601 tgcttgaaat aacagtaaat cgcaaaaatc gacaggacag aaacaaatcc tgaaaaaagg
     6661 gcagtacgca ttagcatgac agtccaggaa atgtcagcag aaacgaagtt cttgaccata
     6721 aacacacccg tagtgcccag atagccgaaa gaatcggcca aataaataat aaaaacagcc
     6781 gtactaacca ccctaaggga agcaatcaga cgttctatca ggtaagtgaa aggaatatac
     6841 cccatataca gaccaagacc ggaaagaatc atccaccaaa taggagaaag aaaaccgtac
     6901 acataaagca atgtggaaaa aaccattaag gaaccgcctg tgacggcaat gcaataaatg
     6961 atattaagag ccaaacggtt attacggaca aacacaatca ggaacatcag tacaaggaca
     7021 aaaacggcaa tgggaacctc tgtctgagta aagatcattg caccctcaat atggagctcc
     7081 ttccaaatat cggcagcgaa agagtcacga agctcacgga acacggtcag ggcaccgtaa
     7141 aaaacaacca gcatgcagat tccccagaag aattgcctca aaaatttacg cctgtcttta
     7201 ccatccatcg gagcacgttt ggtacgctgt atgatatctt gctcattggg agccggaatc
     7261 tgattgagaa gccagctgca aagcaacata acagggtata ccaacaaacc tgtggtaaaa
     7321 ggcatccaat attccgacac atgcaaatta tccatcacga attgtcccaa ggttttcacc
     7381 aaaccggaag agactatcaa agcaacgctc agcccgacat tcaatatttc actgatacga
     7441 cgcccttcga tatagctaaa aatgacaccc cagatcatac ccaggggaag accgctcaga
     7501 aaaatagaac acaccttcaa aggaaccgga agaagtgcaa aacccaacaa agcaacttcg
     7561 gaaaaagtaa gcagccctat tatataatag atgcggtgac ccgctttcat cgaaggcaaa
     7621 atacgaacac cgatgaactt ggaaagggcg tagccgataa tctcagaaag gacatacaga
     7681 attttgacat cgaatcccca aagaatctca ccttcataaa tggctgcggt aaatggctta
     7741 cggtaggcat aggcacaagt ataaaccaga aaaatcaaaa cgctggcata gagagccaaa
     7801 acgtaaaggg gagaacggga aagaaaggaa cgaatcattc gtgtagttcg ctgtacggat
     7861 a
//
