LOCUS       c00043_gnlPro..        15794 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FGBGCNEI_43.
ACCESSION   c00043_gnlPro..
VERSION     c00043_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 18:09:10
            Original ID  :: gnl|Prokka|FGBGCNEI_43
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15794
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..645
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Transketolase_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Transket_pyr"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg43_1"
                     /sec_met_domain="Transketolase_C (E-value: 6.7e-10,
                     bitscore: 30.1, seeds: 80, tool: rule-based-clusters)"
                     /sec_met_domain="Transket_pyr (E-value: 5.3e-14, bitscore:
                     43.4, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="IWTHDAFRVGEDGPTHEPVEQEAQIRLMEKLKNHKGHNSMLVLRP
                     ADAEETTVAWKLAMENTSTPTALIFSRQNIANLPAGNDYSQAAKGAYIVAGSDENPDII
                     LVASGSEVSTLEAGAELLRKDGIKIRIVSAPSEGLFRSQSKEYQNSVIPTEAKVFGLTA
                     GLPVNLEGLVGANGKVFGLESFGFSAPYKVLDEKLGFTAQNVYNQVKEMLA"
     protocluster    1..15794
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2956:5794]"
                     /cutoff="5000"
                     /detection_rule="(Fer4_7 and TPP_enzyme_C and POR and POR_N
                     and PFOR_II and not (EKR or Fer4_16))"
                     /neighbourhood="10000"
                     /product="porA"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2957..5794
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="(Fer4_7 and TPP_enzyme_C and POR and POR_N
                     and PFOR_II and not (EKR or Fer4_16))"
                     /neighbourhood="10000"
                     /product="porA"
                     /protocluster_number="1"
     cand_cluster    1..15794
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Fer4_7 and TPP_enzyme_C and POR and
                     POR_N and PFOR_II and not (EKR or Fer4_16))"
                     /kind="single"
                     /product="porA"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15794
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="porA"
                     /region_number="1"
                     /rules="(Fer4_7 and TPP_enzyme_C and POR and POR_N and
                     PFOR_II and not (EKR or Fer4_16))"
                     /tool="gutsmash"
     CDS             642..1076
                     /locus_tag="ctg43_2"
                     /transl_table=11
                     /translation="MKKVGLASDHAGFELKEFVKTWLTEKGYPCKDFGTYSTESCDYAD
                     YAHPLALAIEAGECGPGVAICGSGEGISMTLNKHQGIRAALCWIPEIAHLSRQHNDANV
                     LVMPGRFIDHEMAEKILDEFFNSGFEGGRHQKRIEKIPVK"
     CDS             1204..2280
                     /locus_tag="ctg43_3"
                     /transl_table=11
                     /translation="MLLCLPFIAMAQTDPKYLAGAITLDDGKVSFKTEIQAPSLTKDQL
                     YETMLKWATERFKPEGKFNARVLYTNEDEGTIAAGGEEYLVFSSSALSLDRTRIYYQMF
                     ITCGNGKCDIEMTRIRYWYDEARDGGEKYSAEEWIVDDMALNKSKTKLAPICGKFRRET
                     IDLKDTLFKSIQDTLGNKVLNNSQIAVAPTSGVTATPISNTTTIITATPVTPPAQPAII
                     GGSEGNTEIKVANNVTPSKEQSIDDQIKASSRMTITAGNDEQFEIGKECWGGFGQLFGK
                     EVAFCIIDQSKSMGNMLMDQSDNYKISFYKQGSSEPWLIVNCKKLMKQTVTGEEAKKMN
                     PSNNGQKAYNMYVGEVIK"
     CDS             2668..2946
                     /locus_tag="ctg43_4"
                     /transl_table=11
                     /translation="MTEELQDIKTLIEQGDTERAIHALTNFIRNDAHVNDEPYYLLGNA
                     YRKMGNWQQALNNYLEAIERNPESPAVSARDMIMNILNFYNKDMYNQ"
     CDS             2957..3187
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg43_5"
                     /sec_met_domain="Fer4_7 (E-value: 6.2e-13, bitscore: 40.4,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 7.9e-09, bitscore: 26.5,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 9.2e-09, bitscore: 26.4,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 4.2e-06, bitscore: 18.3,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKIKGAIVVDTERCKGCNLCVVACPLHVIALNAKQVNKKGYTFA
                     HQVLEDTCNGCASCATVCPDGCITVYKVKQQ"
     CDS             3199..4281
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     PFOR_II"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg43_6"
                     /sec_met_domain="PFOR_II (E-value: 2.8e-29, bitscore: 92.6,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 1.1e-51, bitscore: 166.8,
                     seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEEVVLMKGNEAIAHAAIRIGVDGYFGYPITPQSEILETLAEEK
                     PWETTGMVVLQAESEVAAINMVYGGAASGKMVMTSSSSPGVSLKQEGISYIAGAELPCL
                     IVNVMRGGPGLGTIQPSQADYFQTVKGGGHGDYRLIALAPASVQEMADFVGIAFDLAFK
                     YRNPAIILADGVIGQMMEKVVLPEQRTRLTDEEVIARCPWATTGRTHHRTPNIITSLEL
                     DPAEMEKRNIHLQKKYAEIEENEVRFEELHCEDSEYLIVAFGSCARIAQKAMEMAREEG
                     IKVGLLRPITLWPFPSKAIAARAAQVKGILTVELNAGQMVEDVRLAVKCKVPVEHFGRL
                     GGIVPDPDEVITALKEKLIK"
     CDS             4288..4455
                     /locus_tag="ctg43_7"
                     /transl_table=11
                     /translation="MNIDLIRNILNILFMALALAAVITYFVASDFKVFIYVCAAAIFLK
                     LVEFFMRFML"
     CDS             4474..5238
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg43_8"
                     /sec_met_domain="TPP_enzyme_C (E-value: 7.7e-26, bitscore:
                     81.8, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKEEIIKPENLVYKKPTLMNDNPMHYCPGCSHGVVHKLIAEVIE
                     EMGMEDKTIGVSPVGCAVFAYNYLDIDWQEAAHGRAPAVATAIKRLWPGRLVFTYQGDG
                     DLACIGTAETIHALNRGENITIIFINNAIYGMTGGQMAPTTLVGMKTATCPYGRDVAIH
                     GYPLKMTEIAATLEGTAYVTRQSVHTVPAIRKAKKAIRKAFENSMNGKGSNLVEIVSTC
                     NSGWKMTPQASNDWMVEHMFPFYPLGDLKNKE"
     CDS             5252..5794
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     POR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg43_9"
                     /sec_met_domain="POR (E-value: 8.2e-36, bitscore: 114.8,
                     seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQEIIIAGFGGQGVLSMGKILAYSGLMEDKEVTWMPAYGPEQRG
                     GTANVTVIVSDERISSPILSQYDTAIILNQPSLEKFEGKIKPGGILIYDGYGIIEPPTR
                     RDIRIYRIDAMDAANEKGMAKTFNMIVLGGLLKLRPVVSIESVIKALRKTLPERHHHLI
                     PMNEEAIRIGMEIIKPQ"
     CDS             complement(6431..6715)
                     /locus_tag="ctg43_10"
                     /transl_table=11
                     /translation="MVAGVVIPYLTQSGWDFVGGIFFFAFCHIQRVGDIPVVRDTSVFC
                     HLQVIVVEYEMHVIFISPVAGEQATVEEGCGLILIKPPAIQVIYVESEP"
     CDS             6770..7999
                     /locus_tag="ctg43_11"
                     /transl_table=11
                     /translation="VDTDSVKITQVFVPVTSFIHTLQVDLNNRKYISYDDAQNQKYFEH
                     NYLGTDSIDKTKRTSIKNTIGIALQEGFNKWAKAGLTAFLSYEYRNFALTDTTNIPGQR
                     IINNYKESSLSIGGELSKKQGKLLHYNILGELAIAGEDAGQFSVEGRGDLNLRLFGDTV
                     RLDVNAFIKNQNPVFYFRHFQSKHYWWDNNDLSKIMRTRLEGKLSLDRWGTQLRAGVEN
                     IKNYTYLANTSIPVKDSEGNVTGFKNNAAVRQHSGNIQIFTAMLQQKLKVGIFHLDGEV
                     AYQKSSEQDILPLPELSAYGNLYMKFGLAKKVLQIEMGADVRYFSKYYAPDYSPVIGQF
                     YNQNPDDKIEIGAFPIVNVYANLHLKRTRFFIMMYHVNAGSGKSNYFLAPHYPINPRMI
                     KFGLSWNFFD"
     CDS             8008..8826
                     /locus_tag="ctg43_12"
                     /transl_table=11
                     /translation="MKKYLKYVLMGILAATLSSIFFKKKTEAETSLPRDYAEIAASGIL
                     RAVTEYNSISFYADGDTVSGFHYELLHAFAHSKGLKPEITPEMSFSKRLEGVQKGTYDI
                     LANSTVVTTEYKDSLLFTRPIILNKQVLVQRKPEKENDSLYIHSQLELARKTLHLVKNS
                     PAILRIHNLSNEIGDTIYIKEVEKYGQEQLLAMVAHGDIDYAVCDESIAKASINDFPQL
                     DIETAISFSQFYSWGVSKHSPILLDSLNSWLNDYVKTPAFKLLRKKYYNN"
     CDS             8915..9904
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg43_13"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 1.4e-26, bitscore:
                     84.9, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVKLDKVKWGFIGCGEVTEKKSGPAFALIEGSEVVAVMSRDKEKA
                     QSYAKRHNIPRWYSDPQQLIGDEDVNAIYIATPPSSHATFAIMAMKAGKPVYIEKPMAA
                     SYEDCARINRISQETGIPCFVAYYRRYLPYFQKVRQMVEDGEIGNVINIQIRFAQPPRD
                     LDYNSTNLPWRVQPDIAGGGYFYDLAPHQLDLLQDMFGCILEAQGYKSNRGGLYPAEDT
                     ISACFKFDSGLPGSGSWCFVAHESAKEDRIEIIGDKGMICFSVFTYDPIALHTERGREE
                     FLPENPPHVQLPLIKAVVEHLQGKAVCTCDGISATPTNWVMDRILNKL"
     CDS             9914..11041
                     /locus_tag="ctg43_14"
                     /transl_table=11
                     /translation="MDIRKLCLLCLSFLSAFNVYAQAEKKDSTVQDNKGVLITLTDGIA
                     TTVRHTGRKIRKVGKEFNAIDTTYISPNLYNLAFMLESSSWYEYYRLGSKGNNGEQSLG
                     FSPNASFKLGVYFGWRWIFLGYSFDVKDIFGGHKNKAKKTEMALNLYSSKFGVDLYYRK
                     TGSDFKIRSSSGFDLNTPIKNLNFNGLQSKIKGLNAYWIFNYKKFSYPAAYSQSTNQRK
                     SAGSLMAGFSYSQHNISFDYEKLPGEVRVQLHDALLFKKVKYSDYSINVGYGYNWVFAK
                     NWVSNLSLLPAIAYKKSKIDDTPNTDNHWIKDINFDLITRAAVVYNTNKYFIGASLVMH
                     TYDYRKKDFSLTNTFGTVRIYAGFNFWKKKEFRDK"
     CDS             complement(11289..12080)
                     /locus_tag="ctg43_15"
                     /transl_table=11
                     /translation="MEQKDKYIRFDWAIKRLLRNKANFGVLEGFLTVLLGEKIQIMEIL
                     ESEGNQQREDDKFNRVDIKARNSKDEIILVEVQNTRELYYLERILYGVAKAITEHIDLG
                     GIYANVKKVYSISILYFDIGQGNDYLYHGQNTFLGVHTGDCLKVTTKEQGAIIRKLPAE
                     IFPEYFLIRVNEFNKVAVTPLEEWIEYLKTGTIRPDTTTPGLEEARQKLIYYNMNKADK
                     LAYDRHLDALMIQNDVLSTAKLEGLEEGRVEGREEGIMVGR"
     CDS             complement(12213..13511)
                     /locus_tag="ctg43_16"
                     /transl_table=11
                     /translation="MNENKTRASFDQIGFVYSNKIGNNTSLRFVNFGFNYHKSKNFNRL
                     FSMGGALDNLSQSFQLAQEMERYGLTESEFNDILDVKNPYTKYWNQLPVLGVMGVRTGV
                     VDWVNDSEKNIHAPWGWNGFNNNFFSKETGGISQYDFNVSFNIEDRVYLGATLGVYDVN
                     YDRYTSYTENLNDDNGADNGGYTLDNYYRLEGTGMDLKLGVIIRPIESSPFRLGFAVHT
                     PTWYDLRESYNAALSSNILACEAPYNQTLSDFLVTPEYDYLTYDYNLTTPWKFNVSAGT
                     TFAGAVAVGAEYEYQDYSSSKLKDVDGYELGDQPSVENYLKGVHTFRIGMETRIIPEFS
                     IRAGYNYSSAAFSKDAYSALSLYSTRTDFNNTESKNTFTFGLGYRGSVIYADLAYKYDM
                     YKSNFYAFDDIDLPATKVDNERHQLLLTVGARF"
     CDS             complement(13821..14225)
                     /locus_tag="ctg43_17"
                     /transl_table=11
                     /translation="VLSEPVPEKLFHQVRQQEFVRVIRIHVRQKEGVLPIPDQAVLGAV
                     WEMQQDLLIREQGLQVVALIVTIVAFRILVAVHTLVAVVLLVIVRLTLTVVVELLLPVV
                     VFLVAVVLLAVPVAVFPVQVVAADRVPDKW"
     CDS             complement(14385..14729)
                     /locus_tag="ctg43_18"
                     /transl_table=11
                     /translation="MHTSFPLTRTAYGGIGVGIIHMAPVGDSVGDGVRHGTTIVGTIPV
                     IGVAATGVAIGATIITITIIIRITLVTVGVVATGEVVMDGMAQADVTRGYMPEDIPIAI
                     VLHAQAGIIT"
ORIGIN
        1 atctggacac acgacgcatt ccgtgtaggt gaagacggtc ctactcacga accggtagaa
       61 caagaagcac aaatccgcct gatggaaaaa ctgaaaaacc acaaagggca caattctatg
      121 ttggtactcc gtccggcaga tgcggaagag accactgtag cgtggaaatt ggccatggaa
      181 aataccagca cccccaccgc actaatcttc tcccgccaga atatcgcgaa tctgcctgca
      241 ggaaacgact actcacaggc tgcaaaaggc gcttatattg ttgcaggttc cgacgaaaat
      301 ccggatataa tcctagtcgc ttcaggttcc gaagtttcca ctttggaagc aggtgcagaa
      361 cttctccgca aggatggcat aaaaatacgt atcgtatccg ctccttctga gggattgttc
      421 cgcagccaaa gcaaggaata ccaaaacagt gtcattccca cagaggctaa agtattcggt
      481 ctgactgccg gtcttcctgt aaaccttgaa ggtttggtag gtgccaacgg taaagtattc
      541 ggtctggaat cattcggatt ctccgctcct tacaaagtat tggatgaaaa gctgggcttt
      601 accgcacaga acgtgtataa ccaagtaaaa gaaatgctgg catgaaaaaa gtaggactgg
      661 catccgatca tgcaggattt gaactgaaag agtttgtaaa aacatggttg actgaaaaag
      721 gttatccatg caaagatttc ggtacataca gtacagaaag ctgtgactat gcagattacg
      781 cccatccgct tgcactggct atagaagccg gagaatgcgg acccggagta gctatttgcg
      841 gaagcggtga agggatcagc atgacattga acaaacatca gggtatccgt gcggcactat
      901 gctggattcc cgagatagcc catttgtcac gtcaacacaa tgatgccaat gttctggtaa
      961 tgccaggacg attcatagac catgaaatgg ctgaaaaaat attagatgaa ttctttaaca
     1021 gcggctttga aggcggacgt caccaaaaac gcattgaaaa gatacctgta aagtaaaatt
     1081 cacgcaataa taataaaagt aaaaaaagag aggctttata gcttctcttt ttttttattc
     1141 ctatctttgc ttagattaaa atataaaata agatatatta ctatgaagaa aattcttttt
     1201 ttaatgctct tatgcctgcc attcatcgct atggcacaga cagatcccaa atatctggcg
     1261 ggagcaataa ctttggatga cggtaaagtt tctttcaaaa cagaaataca ggcaccgtct
     1321 ttaacgaaag accagctata tgagacaatg ctgaaatggg ctacagaacg tttcaagccc
     1381 gaaggcaagt tcaatgcacg tgttctttac accaatgaag atgaaggaac cattgcagca
     1441 ggtggcgaag aatatctggt attctcatcc tctgcattgt cattggacag aaccagaatt
     1501 tattatcaga tgtttatcac ctgcggaaac ggaaaatgtg atatcgaaat gacccgtatc
     1561 cgctattggt atgatgaagc tcgtgacgga ggagaaaaat acagcgcaga ggaatggatt
     1621 gtagacgata tggctttaaa caaatcgaaa accaaactgg ctcccatctg cggcaaattc
     1681 agaagagaaa caattgactt gaaagacaca ctgttcaaat ccatccaaga tacattgggc
     1741 aacaaagtct tgaacaactc acaaattgca gttgctccta cttcgggtgt aacagccact
     1801 ccgatatcaa atacaaccac aatcattacc gccactccgg taactccccc tgcccaaccg
     1861 gctatcatcg gtggttctga gggtaatacc gaaataaaag tagccaataa tgtaactcct
     1921 agcaaagaac aaagcataga tgaccaaatc aaggcatctt cacgtatgac aattactgcc
     1981 ggaaacgatg aacaattcga aattggtaaa gaatgttggg gaggtttcgg tcagttattc
     2041 ggcaaagaag tagcattctg cataattgac caatccaaat caatgggcaa tatgctaatg
     2101 gatcaaagcg acaattataa aatttcgttc tacaagcaag gtagtagtga gccgtggttg
     2161 atagtaaact gtaagaaact gatgaaacag acagttaccg gtgaggaagc aaaaaaaatg
     2221 aaccccagta acaacggcca gaaggcatat aatatgtatg taggtgaagt aataaaataa
     2281 tcttttcttc tatatattta tgccgtgaca gttaattcta tacgataata cataaaatat
     2341 ttaggggggg agataacctg acaactcccc ctaaaaaaca tacaaacgat ttaccatata
     2401 cttcccccca aaaatatcat gacaaataca attcaaacat atcccccctt taagaataaa
     2461 taacaccgtt cctctatcaa ccgtttcact tgaaaccatt tctataataa tcaaaccatt
     2521 agaagaaatc attcttccat tttttcccta tctttctctc ctttttttaa atgtttttag
     2581 caagaaagtc gttttttctg ctccaatctt ccctttcata acaaataaag agtatctttg
     2641 taaacaacaa tgagacaatc atgccttatg acggaagaat tacaggacat aaagacactt
     2701 atcgaacagg gtgatacgga gagagctatt catgcgctaa ctaatttcat ccgaaacgat
     2761 gcgcacgtca acgatgaacc ctattactta ctgggtaacg cctaccgcaa aatgggaaac
     2821 tggcaacaag ctttgaacaa ttatttggaa gccatcgagc gtaatccgga aagtcccgcc
     2881 gtttccgccc gtgacatgat tatgaatatt ctgaatttct ataacaaaga catgtataat
     2941 caataataac taacccatgg caaagattaa aggtgctatt gtagtagaca cagagcgttg
     3001 caaaggttgc aatctatgtg tagtggcatg tccgctacat gtaatcgcgc tcaatgccaa
     3061 acaagtgaat aaaaaaggat acacattcgc ccaccaggta ttagaggata cctgcaatgg
     3121 ttgcgcatca tgtgccacag tctgtccgga cggatgcatt actgtgtata aagtaaaaca
     3181 acaataaatg taacaaatat ggcagaagaa gtcgttttaa tgaagggaaa tgaagccata
     3241 gcccacgccg ccatccgtat cggagtagac ggttactttg gctatcccat cactccccaa
     3301 tcggaaatat tggaaacgct ggccgaagag aaaccttggg aaactaccgg tatggtggtg
     3361 ttacaggcag aaagtgaagt cgcagcaatc aacatggtat atggcggtgc agcaagcggt
     3421 aaaatggtaa tgacctcatc ctccagtccc ggcgttagtt taaagcagga aggcatctcg
     3481 tacattgccg gtgccgaact cccctgcctg attgtcaatg tcatgcgcgg aggtcccgga
     3541 ttaggaacca tccaacctag tcaggccgac tatttccaaa cagtgaaagg tggcggtcac
     3601 ggagactatc gtctcatagc cctggcacct gcatcagtac aggaaatggc agatttcgta
     3661 ggtatagctt ttgatttggc tttcaaatac cgcaatcccg ccattattct ggcagatggc
     3721 gttatcgggc agatgatgga aaaagtagta ttacccgaac agcgcacacg cctgacagat
     3781 gaagaagtca ttgcccgttg tccgtgggcc actaccggca gaacccacca ccgtaccccc
     3841 aacatcatta cctcattaga actcgatccc gccgaaatgg aaaagcgcaa tattcatctt
     3901 cagaaaaaat atgcagaaat agaagagaat gaagtacgct tcgaagaact tcactgcgaa
     3961 gattcagaat atttgatcgt agctttcggc tcttgcgccc gcattgccca aaaggcaatg
     4021 gaaatggctc gggaagaagg catcaaagtt ggtttgctcc gtcctattac cctatggccg
     4081 ttcccgtcga aagctattgc agcacgcgcc gcacaggtaa aaggtatcct cactgtagaa
     4141 ttgaacgccg gacaaatggt agaagatgtc cgtctggctg taaaatgtaa agtgcctgta
     4201 gaacacttcg gacgtctggg tggtattgtc cccgatccgg atgaagtaat cactgcactg
     4261 aaagagaaac taataaaata agaccgtatg aatatcgatc tgatcagaaa tatattgaac
     4321 atacttttca tggcactggc attagcagct gtcatcactt actttgtggc aagtgacttc
     4381 aaagtattca tctatgtctg tgcagcagct atttttctca agctggtgga attctttatg
     4441 cggttcatgt tataaacaat aggaggagaa actatgacaa aagaagaaat cataaaaccc
     4501 gaaaacctgg tttataagaa accgacactg atgaatgaca atccgatgca ttattgcccc
     4561 ggatgcagcc acggtgtggt tcacaagtta atagccgaag ttattgaaga aatgggcatg
     4621 gaagataaga caatcggtgt gtcaccagta ggatgtgccg tatttgcata caattatcta
     4681 gacatcgatt ggcaagaagc cgcccacgga cgcgcaccag ccgtagctac cgccattaag
     4741 cgtttatggc ccggacgtct ggtatttacc taccaaggag atggtgactt ggcatgtatc
     4801 ggtactgccg aaactatcca tgctttaaat cgtggtgaaa acattactat catctttatc
     4861 aacaatgcca tttatggaat gaccggtggg caaatggctc ctaccactct ggttggcatg
     4921 aaaacagcca cctgccccta tggtcgtgat gtagccattc acggctatcc gctgaaaatg
     4981 acagaaattg ccgccacttt ggaaggcacc gcctacgtta cccgccagtc cgtacataca
     5041 gttcccgcca tccgcaaagc caaaaaggct atccgcaagg catttgaaaa ttcaatgaat
     5101 ggcaaaggtt ctaatttggt ggaaattgta tcgacttgta attccggttg gaaaatgact
     5161 ccgcaagcat ccaatgactg gatggtggaa cacatgttcc ctttctatcc gctgggtgat
     5221 ttgaaaaata aagaataaaa agacagaaac catgaaacag gaaatcatta tagcaggatt
     5281 cggcggtcag ggtgtgctat ccatgggtaa gatacttgcc tattccggac tgatggaaga
     5341 caaggaagta acctggatgc cggcatacgg tcccgaacaa cggggaggaa ccgctaacgt
     5401 aacggtgatt gtcagtgatg aacgcatctc ttcacccatt ctcagccaat atgacacagc
     5461 catcatactg aaccaaccct cattggaaaa gtttgaaggc aaaattaaac caggtggtat
     5521 tctcatttat gacggatacg gaatcatcga gcctccgaca cgtagggaca tacgaatcta
     5581 tcgtattgac gcaatggatg ccgccaacga aaaaggaatg gcaaagacct tcaacatgat
     5641 tgtcttagga ggcttgctaa aactacgtcc cgtagtatcc attgaaagtg taataaaagc
     5701 tttacgcaaa acattacccg aacgtcacca tcatctgata ccgatgaatg aagaagccat
     5761 ccgaatcgga atggagatta ttaaacctca gtaagttaaa ataactctaa acgaataata
     5821 aaaggaagaa ctttccatag cggaaaagct cttcctttta tttttatatt gtatctttgc
     5881 cgccgttatg aaaagaatat tctctattat ttttttatta ttcctgtgct tccatacttc
     5941 cttgatggca cagcggacaa tgaataccct gaacaaccag ttcggttcct cagcaagcgg
     6001 actgaacaga gatcaatatg accgtaacgg aaaccccata gacacgacag ccgtagtaga
     6061 tgccagcaca atccccatcg gactgtactc atggaaagtg gacagtcgtt ttggcaatgt
     6121 cacttatatc cccgtagata ccttgcagca cgctttccaa aactcaaatg acatgggcgg
     6181 ctataccgga caatacaatt acctgggaaa tttgggctcc ccccgcctct cacgcatctt
     6241 ttttgaccgt cgggacccca gccaatactt tttcaccgac ccatacgatt tttgcgtaca
     6301 acgtccggaa gatgtcatat tcaccaatac actttctcca ttcacaaacc tgacctatta
     6361 caaaggagga ggcagccgtg acggagaaga acgtttcaaa tcctattttg ccatcaatgc
     6421 aaacaaaagg ctagggttcg gattctacat agattacctg tatggccggg ggctttatca
     6481 agatcagtcc acagccttct tcaacggtgg cctgttctcc agctaccggg gagataaata
     6541 tgacatgcat ttcatattca acaacgataa cttgaagatg gcagaaaacg gaggtatcac
     6601 ggacgaccgg tatatcacca acccgctgga tatggcagaa ggcaaaaaag aatattccgc
     6661 caacgaaatc ccaacccgac tgagtcagat atggaatcac aacaccagct accatgcctt
     6721 cctgacacat cgttacaacc tagggttcta taaagaaaaa caggacagtg tggatacgga
     6781 ctctgtaaaa ataacgcagg tatttgttcc tgtcacaagc ttcatacata cactacaagt
     6841 agacttgaac aatcgcaaat acatctcata cgatgacgca cagaatcaga agtattttga
     6901 acataactat ctggggaccg actctataga caagacgaag cgtacatcca tcaaaaacac
     6961 cattggcatt gctttacaag aaggattcaa caaatgggca aaagccggac ttaccgcctt
     7021 tttaagttat gaataccgaa acttcgcctt gaccgacaca acaaacatac cgggacaacg
     7081 cattatcaac aactataagg aaagttcact ctccattggc ggcgaactat ccaaaaaaca
     7141 aggaaaacta ttacattaca atatcctagg agaattagcc atagccggtg aagacgcagg
     7201 acaattcagc gtagaaggca gaggggatct gaatctccgt ttattcggag atacggtgag
     7261 actggatgta aatgcattca tcaagaacca gaaccccgta ttctatttca ggcatttcca
     7321 gtccaaacat tactggtggg acaacaacga tttatccaaa ataatgagaa cccgcctgga
     7381 aggaaaacta agtctggaca gatggggaac ccagctgcgt gccggagtgg aaaatataaa
     7441 gaattacact tatctggcca ataccagcat accggtaaaa gacagtgaag gaaatgtcac
     7501 cggtttcaag aacaatgcag ccgtaagaca acactccggc aacatacaaa tattcactgc
     7561 aatgttgcaa caaaaattaa aagtaggaat ttttcatctc gacggtgaag tagcctatca
     7621 aaaatcaagt gagcaagaca ttctaccctt accggaattg tcggcttacg gcaacttgta
     7681 catgaaattc ggtctcgcca aaaaagtact ccagatagaa atgggagcag atgtgcgtta
     7741 tttcagtaaa tattacgcgc cagactactc ccccgtcatc ggacaattct ataaccagaa
     7801 tcctgatgac aaaatcgaga taggagcttt tccgatagtc aacgtctatg ccaacctgca
     7861 tttaaaacgt acccgcttct ttattatgat gtatcatgtc aatgccggtt cgggaaaatc
     7921 caattacttc ctggcgccac actacccaat caatccgcga atgataaagt tcggcctttc
     7981 atggaatttc tttgattgac ggtctatatg aaaaaatatc tgaaatacgt tctgatgggt
     8041 atccttgcag caaccctatc ctccatcttc ttcaaaaaga aaacggaggc tgaaaccagt
     8101 ctgccccgcg attatgcaga aatagcggca tcgggaatcc tgcgtgctgt taccgagtac
     8161 aactcaatca gtttttatgc cgacggcgac accgtttccg gtttccacta cgaactgctc
     8221 catgcttttg cacacagcaa aggactgaaa ccggaaatca ctcccgaaat gagcttttcc
     8281 aaaagactgg aaggcgtaca aaaaggaaca tacgatatat tggccaacag cacggtagtt
     8341 accacagaat acaaagactc cctgttgttt acccgcccca ttatactgaa caaacaagta
     8401 ctggtacagc gtaaacccga aaaagaaaac gatagtctgt acattcacag ccagttggaa
     8461 ctagcccgca agacccttca tctagtcaaa aactcacctg ccattctgcg catacataat
     8521 ttaagtaacg aaataggtga taccatctat atcaaagaag tggagaaata cggacaagaa
     8581 caattactgg ccatggtagc acatggtgac atagactatg ccgtatgcga cgagagcatt
     8641 gccaaagctt ccatcaatga ttttccacaa ttggatatag aaacagccat cagcttctca
     8701 caattctatt catggggagt aagcaaacat tctccaatat tgcttgacag cctgaattcc
     8761 tggttaaatg attacgtcaa gactcctgca ttcaaactgt tgcgcaagaa atattacaat
     8821 aactgatttt tatccagctg aaattgcaaa atagtcctat ctttgcaata taaattgtta
     8881 ttattttaag cggaatgaca aaaaagttat taccatggtt aaattagaca aagtaaaatg
     8941 gggcttcatc ggttgcggag aagtgaccga gaagaaaagc ggaccagcct ttgccctgat
     9001 cgaaggttca gaggtagtgg ctgtaatgag ccgtgacaaa gaaaaagctc aatcatacgc
     9061 caaaagacac aacattcccc gctggtactc cgatccgcag cagttaatag gagatgaaga
     9121 tgtcaatgct atttatatag ccactccccc ttcctctcat gccactttcg ccattatggc
     9181 tatgaaggca ggaaagcccg tgtatattga aaaaccaatg gcagccagct atgaggactg
     9241 cgcacgcatc aaccgcatat cacaagaaac tggtatccct tgtttcgtcg cttactacag
     9301 acgttatctt ccctatttcc aaaaagtacg ccaaatggta gaggatggtg aaataggtaa
     9361 tgtcatcaat atacagatac gtttcgccca gcctccccgt gatttggatt acaacagcac
     9421 caacctgccc tggcgtgtac aacctgatat tgccggcggc ggttatttct atgatctggc
     9481 tcctcaccag ctggatttat tacaagatat gttcggctgt attctcgaag cccaaggata
     9541 caagagcaac cgtggcgggt tatatccggc agaagatacg ataagtgcct gcttcaaatt
     9601 tgattccggt ctgccgggat caggatcatg gtgttttgtc gcccatgaat cggccaagga
     9661 agaccgtata gaaatcatcg gagacaaggg gatgatctgt ttttccgttt tcacttacga
     9721 tcccatcgcc ctgcatactg aaagaggacg cgaggaattt cttcccgaaa atccccctca
     9781 tgtacaactt ccgctcataa aagccgtagt agaacacctg cagggaaaag ctgtctgtac
     9841 ctgcgacggc atcagtgcga cacccaccaa ctgggtaatg gaccgtatac ttaataaact
     9901 ctgatttccg cctatggaca tccgtaaatt atgcctgctc tgtctgtctt ttctttctgc
     9961 ctttaatgta tatgcacaag cggaaaagaa agactcgaca gtacaggaca acaagggtgt
    10021 tctcattaca ttgactgacg gaatagcaac gactgtccgc cataccggaa gaaaaataag
    10081 gaaagtagga aaagaattca atgcgattga cactacctat atctcgccca acctttacaa
    10141 tctggctttc atgctggaat ccagcagttg gtacgaatac tatcggttag gtagtaaagg
    10201 aaacaacggc gaacaaagtt tgggattctc ccccaatgcc agtttcaagc tgggagtcta
    10261 tttcggatgg cgctggatat ttctaggata ttctttcgat gtaaaagata ttttcggcgg
    10321 acataaaaac aaggcaaaga aaaccgaaat ggcactgaat ctttatagtt ccaaatttgg
    10381 tgtggattta tattacagaa agacaggaag cgatttcaag atacgttctt ccagcggttt
    10441 tgatctgaat actcccatta aaaatttgaa tttcaacgga ttgcaaagta aaatcaaagg
    10501 actgaacgcc tattggattt tcaattataa aaaattctct tatccggcag cctatagcca
    10561 gtccaccaac cagcgtaaaa gcgcgggttc cctgatggcg ggcttttctt attcccagca
    10621 caacatatct tttgattacg aaaagcttcc cggtgaagtg agagtccaac tacatgatgc
    10681 tttacttttc aagaaagtga aatattctga ttacagcatc aacgtgggtt atggctataa
    10741 ctgggtattt gcaaaaaact gggtttccaa tctttcactc ttaccggcca ttgcctataa
    10801 aaaatcaaaa atagacgata cacctaatac tgacaatcat tggataaagg atatcaattt
    10861 tgacctgata acacgtgctg ccgtggtcta taacaccaac aaatatttta taggagcttc
    10921 gttggtgatg catacatacg actatcgaaa aaaggacttc tccctcacta atactttcgg
    10981 aactgtccgt atatatgcag gattcaactt ttggaaaaag aaagagttcc gtgataaata
    11041 ggaggaggat gacaaaaacg gaaagtgaaa aaagagaaat gaagaatcca atcacatcca
    11101 tttgttctca caagatccct caccatgact caaaatgaca gaatccgtga ttacacaaca
    11161 gaatcctgac ataccttcat tcattaaagt ctatctattt catctataga caagcctgta
    11221 gcttgaacaa taacagcaat aggaatattc aaagatttca agttacgggc tgtagctatt
    11281 ttttcttctt agcgacctac catgatacct tcctcacgtc cttctacacg accttcctct
    11341 aatccttcta atttagcggt actcaataca tcattttgta tcatcaatgc atccagatgc
    11401 cgatcataag ccagtttatc agccttattc atattataat aaataagttt ctgtctcgcc
    11461 tcctccaatc cgggagtcgt tgtatccgga cggatagttc cagtcttaag atattctatc
    11521 cattcttcca aaggagtaac cgccacttta ttaaactcat tcacacgaat aagaaaatat
    11581 tcaggaaata tttcggcagg caatttgcgg ataatagccc cttgttcttt agtggttact
    11641 ttcaaacagt caccagtatg gacaccgagg aatgtattct gaccatggta gaggtaatca
    11701 tttccttggc caatatcaaa ataaagaata ctgatagaat acactttctt gacatttgca
    11761 taaattccac ctaaatctat atgttcggtt attgcttttg ctactccata aagtattcgt
    11821 tcaagataat ataactcccg cgtattctgc acttccacta gtattatttc atccttgcta
    11881 ttacgggctt taatatctac ccggttgaac ttatcatcct cccgttgctg gttaccttcg
    11941 ctctcaagga tttccatgat ttgaatcttc tcacccaaaa gtacggtaag aaaaccttcc
    12001 aggacaccaa aattggcttt gttgcgtaaa agacgcttga ttgcccaatc aaaccgtatg
    12061 tatttatctt tctgttccat aaaaacctct ttttacaaag ataacccttt tgtttgaaaa
    12121 ccaggatgaa acattagcaa aaaatatacc ggaaagcaat aaagcattcc cggtatatca
    12181 caagttaatt atattagact cacaattaat tcttagaaac gagcaccgac agtcaaaagc
    12241 aactgatgcc gttcattgtc cactttagtt gccggaagat ctatatcatc aaaagcataa
    12301 aagtttgatt tatacatatc atatttatat gccaaatccg cataaattac actgccacgg
    12361 tatccaagac caaacgtaaa tgtattctta gactccgtat tattaaaatc agtacgcgtg
    12421 ctatataaag acaaggcact ataagcatct ttagaaaaag cagccgaaga gtaattatat
    12481 cctgcacgaa tgctaaactc aggtataatc ctcgtttcca ttccgatacg gaaagtatgg
    12541 acacctttca aataattctc aacgctgggc tgatctccca attcataacc atccacatcc
    12601 ttgagcttac tggaagaata atcctgatat tcatattccg cacctactgc cactgcaccc
    12661 gcaaaagtag tacctgcgct gacattaaat ttccacggag tggtaagatt ataatcatag
    12721 gtcaaataat catattccgg agttaccaga aaatcactca atgtctggtt atagggtgcc
    12781 tcacaagcta aaatattaga agataaagcg gcattatagc tttctcttaa atcataccat
    12841 gtaggcgtgt gcacagcaaa tcccaaacgg aaaggggaac tttctatagg ccgtataata
    12901 acacccaatt ttaaatccat accagtccct tccagcctat aataattatc caatgtatac
    12961 cccccattat ccgcaccgtt atcatcattc aaattttccg tataagaagt ataacgatca
    13021 taattcacat catagacccc cagggtagct cctaaataga ccctatcttc aatattgaat
    13081 gaaacattaa aatcatattg actgatacct cctgtttcct tactaaagaa gttattgtta
    13141 aaaccattcc acccccatgg agcatgaata ttcttttcag aatcattaac ccagtcaacc
    13201 acaccggttc tcacccccat tactcctaaa acaggtaact gattccaata tttggtataa
    13261 ggattcttca catccagtat gtcattaaac tcgctttccg tcaatccata tcgttccatc
    13321 tcctgagcca gctggaagct ttgtgacaaa ttatccaacg cccctcccat agagaaaagg
    13381 cgattgaagt ttttactttt atggtaattg aatccgaaat tcacaaaacg caaagaagta
    13441 ttattgccta tcttattgct ataaacaaat ccaatctggt caaatgaagc gcgcgttttg
    13501 ttttcattca ttgacacacc actaaagtta ctctttgtcg aagtattatt aaaaccaaaa
    13561 gaaatagaca cgtcattact acgaaaaatg ccgatacccg cagggttgga gcttatgaca
    13621 gatatatcac cgcccaaagc tcccatggca ccacccatac caacaaatcg tgctgttcca
    13681 ttcaagtcat tccccagcaa cttttccgca tcataagcat tttgtgcgct tgccgttgtc
    13741 attgccaaca acgcacaagc ggttactatt actttatttt tcatacatca attctattaa
    13801 attcaactgt ctagtttaat ctaccactta tctggtacgc gatctgccgc caccacttga
    13861 acgggaaaca ccgccaccgg aactgcgaga agcaccaccg ccactagaaa aactactacg
    13921 ggaagaagaa gttccactac tacggtaaga gttagacgaa ctattacgag aaggactact
    13981 gctacgagag tatgaactgc tacgagaatt cgaaacgcca ctattgttac gataagcgcc
    14041 acgacttgca gcccctgttc tctgataagc agatcctgct gcatttccca cactgctccg
    14101 agtactgctt ggtctggtat aggaagaacc ccttccttct gtcggacgtg aatacgaatt
    14161 acccggacga actcctgctg cctgacttgg tgaaagagtt tctccggtac gggttctgat
    14221 agcacttcta ttaggacgaa ccgaatttac actgttagat cccgaaacca ctcttcctga
    14281 tgaagaaccg ttacgtgttg cggtacgata actattagca ctattacgga cattttgtct
    14341 ggaatttcct acgtatgaat tacgactatt cctatcataa ctattcacgt aattattccg
    14401 gcttgggcgt gaagaactat agctattggt atatcttccg gcatgtatcc ccgggttacg
    14461 tctgcttgag ccataccatc catgactacc tccccagtag ccaccacccc aaccgtgacc
    14521 aaagtaatgc ggataataat ggtgatggtg ataatggtag ccccaatagc caccccagta
    14581 gccgccaccc caataaccgg gatagtacca actattgtag taccatggcg aactccatcc
    14641 ccaactgaat ccccaactgg cgccatatgg ataattccaa cgccaatccc accataagcg
    14701 gttcgtgtaa gtgggaaaga cgtatgcata caatccgtca tcatatacat tccaatccca
    14761 tgaaggcaaa ccgtaaacta catcccaata gagcggactg cttaccggaa tggcgtaacg
    14821 gggattgcgg aaacggacga tacgcatcgc gtattcataa tcgtcttgag aaccctcaaa
    14881 accattaacc cattctcctc tctcattcaa aggtttctcc tcaatataca aggtatcatt
    14941 ctccatcgag aaattattat cacgtgaagt ataacgacga ttatactcat ccacatcgcg
    15001 aacctttcct ttcacatcct tcaccaccac tgtagaaccg ggggctgcgt aaacagtagt
    15061 cgtgttctgc ttctgcggaa ccaccacttt cacctcttgc ttaacctcct ctttcttttc
    15121 agcttttttc ttagggatga aataaaggtc gtcatcaacg ctttgtgaca ttgccaagta
    15181 aggcaagcac accatcataa gcgaagctaa tacaatcttt ttcatactcg tacctgtttt
    15241 atttgttatt ctatctactt tttctagtgc aaagatagtc agaggtttta cttcataaca
    15301 gagaaaatcc ctattagtta gtagggattc ccctatttta gtagcaaagt tcaaagattt
    15361 tatctatttt tgcaattgct atgaaaagtg ggaggataca tatactgctg ctgtctctat
    15421 tgctttgcat ctcttgccgc tatgaacagc aaagttaccc gccactgatg gagcgggcag
    15481 ttcaactaat ggaaactcat cctgacagtg cactagcttg tttggattct ctcagtatat
    15541 ccaccaccga atggcctgaa gagcttcata tatattactt attgctcact gtcaaagcca
    15601 aagacaagct ctatattccg gttacttccg atactttgat taaccgtata attagttttt
    15661 atgaagacaa acaggatgac ccacacctga tggaagctta ttattataaa ggtagtacct
    15721 atcgggatat gaaagatgcg ccacgagccg ttgatgcttt cttgcgtgca gccgaaatag
    15781 ggaaaagatg ttct
//
