LOCUS       c00104_gnlPro..        15654 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FGBGCNEI_104.
ACCESSION   c00104_gnlPro..
VERSION     c00104_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 18:09:10
            Original ID  :: gnl|Prokka|FGBGCNEI_104
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15654
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15654
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3272:6818](-)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      complement(3273..6818)
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..15654
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15654
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             13..633
                     /locus_tag="ctg104_1"
                     /transl_table=11
                     /translation="MGYSVHYFIDVPVIGNFSIQPAIGLSMKGITYEYDKFTTKKSHRV
                     DLDSYKKYDVTESRGTSVTQKHNLGYLDVPILFAYALPLSESFRVQLGVGPYFSYGLFG
                     KFKYESDTYLTVSPDKYGENKHTITKDDCPSFGKNDDGDDPKGNINRFDWGIAIQGSIY
                     WKRLFLNVAYQKGLKSANITDEKNEGKDKLALSNLSLGLGFIF"
     CDS             complement(616..768)
                     /locus_tag="ctg104_2"
                     /transl_table=11
                     /translation="MSFQVNLHFTRQILHFSKKGCTSFIKFLKPLYLSIFQQFLQSVHK
                     LKYKA"
     CDS             complement(1119..1541)
                     /locus_tag="ctg104_3"
                     /transl_table=11
                     /translation="MYVVQRDRLQLSHFFLQQSFIILLSLLSPIPCNPYKQEVREVVAA
                     HYFMYKNAYCHHFIHLVTWYKPTLFVHQTGQACAMNTIGLYGEHGKLVQPRNNDFPCQS
                     IQNLDTSSVGSCSKFHEILYQVLPLHPASFPFGGEG"
     CDS             complement(1541..3058)
                     /locus_tag="ctg104_4"
                     /transl_table=11
                     /translation="MNTLTNLKYTLAVTAGLCSSFAYAQNHPHIILIMTDQQRADAIGC
                     MGNDAVISPNLDALAAEGTLFMNGYSSCPSSTPARAGLLTGLSPWHHGLLGYGKVSPEY
                     KYEMPQMLKDAGYYTFGIGKMHWHPQRVKHGFEGTLLDESGRVEDENFTSDYRQWFQTK
                     APGKNPDATGIGWNDHTASIYKLPENLHPTYWTGEMACELISNYDPTNKPLFLKVSFAR
                     PHSPYDPPQRYLDMYEDALIPDPAIGDWCGKYAKKLNPEKTAQDAPYGNFGNEYARNSR
                     RHYYANITFIDEQIGRIIQTLKEKDMYNDALIVFISDHGDMMGDHYHWRKTYPYEGSTH
                     VPYIVKWPSVDHVTPGKTDAPVELRDILPTFLDAADVTIPTDMDGRSLLPLAKGMETTW
                     RKYLDLEHATCYSDDNYWCALTDGKIKYIWRIHTGTEELFDLTQDPQELHNAVNDKKYR
                     KQLTEMRNEMIRHLSERGEEFVKDGRLVVKEKTMLYGPNYPGKENKR"
     CDS             3130..3309
                     /locus_tag="ctg104_5"
                     /transl_table=11
                     /translation="MVKVEIFEIEVLFCAYVCVASYILMVEKGYKKGLFMKNKPFLYAC
                     IRNYSLQFIASIRL"
     CDS             complement(3273..6818)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg104_6"
                     /sec_met_domain="PFOR_II (E-value: 1.7e-19, bitscore: 59.7,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 1.2e-83, bitscore: 269.9,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 6.7e-32, bitscore: 100.5,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 4.4e-13, bitscore:
                     38.9, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 4.3e-13, bitscore: 39.7,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 4.6e-08, bitscore: 22.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.5e-05, bitscore: 14.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 1.6e-26, bitscore: 81.6,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKQKKFITCDGNQAAAHISYMFSEVAAIYPITPSSTMAEYVDEW
                     AAAGRKNIFGETVLVQEMQSEGGAAGAVHGSLQAGALTTTYTASQGLLLMIPNMYKIAG
                     EFLPCVFHVSARTLASHALCIFGDHQDVMSCRQTGFAMLCEGSVQEVMDMAAVAHLATI
                     KSRVPFVNFFDGFRTSHEIQKIEMLENEDLAGLIDQQALAEFRERALNPNNPVARGMAE
                     NPDHFFQHRESCNNFYEAVPAIVEEYMNEISKITGRPHGLFDYYGAEDAERVIIAMGSV
                     TEAAREAIDYLMSKGEKVGLVSVHLYRPFSAKHFLAAVPKTAKTIAVLDRTKEPGANGE
                     PLYLDVKDCFYGTENAPVIVGGRYGLGSKDTTPAQIIAVFKNLALPMPKNHFTVGIVDD
                     VTFTSLPQEEEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKHCQAYFSYDS
                     KKSGGFTCSHLRFGDTPIRSTYLVNTPNFVACHVQAYLHMYDVTRGLRKNGSFLLNTIW
                     EGEELAKNLPNKVKKYFAQNNITVYYINATQIAQEIGLGNRTNTILQSAFFRITGVIPV
                     DLAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKQLAVDPAWANLEVEAPAANNDP
                     AFINEVVRPINAQDGDLLPVSAFKGIEDGTWEQGTAQYEKRGVAAFVPEWNAENCIQCN
                     KCAYVCPHASIRPFVLDAEEQKGANFETLKAVGKQFDGMTFRIQVDVLDCLGCGNCADV
                     CPGNPKKGGKALTMKHLESQLSQAANWEYCAKNVKSKQHLVDIKANVKNSQFATPLFEF
                     SGACSGCGETPYVKLISQLFGDREMVANATGCSSIYSGSVPSTPYTKNEKGQGPAWANS
                     LFEDFCEFGLGMTLADKKLRARIEAAMKDAIASDTCPAEYKEAFQEWIDGKDDADKSKA
                     AAEKIIPMVEAAKDKCKNCATIAKFKNYLVKKSQWIIGGDGASYDIGYGGLDHVIASGE
                     DVNILVLDTEVYSNTGGQSSKATPLGAIAKFAASGKRVRKKDLGMIATTYGYVYVAQIA
                     MGADQAQTLKAIREAEAYPGPSLVIAYAPCINHGLKAGMGKSQAEEAKAVECGYWHLWR
                     FNPALEEEGKNPFMLDSKEPKWEGFQDFLKNEVRFASVMKQYPAEAADLFAACEEMAKK
                     RYASYKRMEAMNWSE"
     CDS             complement(6861..8039)
                     /locus_tag="ctg104_7"
                     /transl_table=11
                     /translation="METFYRTHSYLVEHTNAPVRRDLMDEIDWNDRLIGIKGTRGVGKT
                     TFLLQYAKEKFGTDHSCLFINMNNFYFSKYTLVEFAAEFVKRGGKVLLIDQVFKYPEWS
                     HDLRACYEMFPTLKIIFTGSSVMRLKEENPELSGIVKVYYLRGFSFREYLNLQSGNCFR
                     AYTLQEILENHEQIAKTILRNVKPLDYFQDYLHHGFYPFFLEKRNFSENLLKTMNMMIE
                     VDILLIKQIELKYLSKIKKLLYLLAVDGPVAPNVSQLATEIQTSRATVMNYIKYLADAR
                     LINMVYPKGEEFPKKPSKLMMHNTNLMYSIYPVKVEEQDVLDTFFMNTLYKDHKLYKGD
                     KGTSFMVDNGLHFRICAEGCKFKNNPNVYYALHKLELGHGNMIPLWLFGFLY"
     CDS             8143..9354
                     /locus_tag="ctg104_8"
                     /transl_table=11
                     /translation="MVCTLKHLSLCPEMEALYLFNPENDMALACGDPYYMAPASARRMA
                     AELSMLPAWYAEEGGTVWLDSAQRMKTMERQSFLPLSVNWVLEFVPIYNKVIPWGWNPS
                     LVRRLQEAGFPDTAYPSVERMKRIRQISGRQTAVKVLRRLCRHIGGNIPILGEAFVLSS
                     TEEVKAFVLSHSRALLKAPWSGSGRGIQYVSGSFPIPLEGWIRHILTTQHEVIGEPFYD
                     KLLDFAMEFFADEWGQVHFIGYSLFETDKRGVYKENLLAADRVIEARISTYVSAEILHQ
                     VGRALQVELAEVIKGSYEGYLGVDMMICRTQNSGYAIHPCVEINLRMNMGVVARLIYDN
                     YVCDGVQGRYVIEYYAKPGEAWHSHLALQEKYPLYLENGKVKSGYLSLTPVENNTSYQA
                     YILI"
     CDS             complement(9393..10766)
                     /locus_tag="ctg104_9"
                     /transl_table=11
                     /translation="MMKHTLLYIAVSGMTLLTSCQLGKHYTRPDLHLPQQLDTLRQQDT
                     LSIADMQWWEIYTDTTLQSLIEKTLDNNKDMKIAAARVKELAAMKRIDFANLFPQLNGG
                     AYAQKEGSNYGGNNYKNDPELGGKLTVTWELDLWGNLRWAKDKSIAQFLGSIEAQRALK
                     MSIVSEVAQAYFELVALDNELNIVRQTLYARKEGVRLAKLRFEGGLTSETSYQQAQVEY
                     ARTATLVPELERKISLKENDIAFLAGEYPHRIQRSILPEEVKLPETLPVGLPSTLLERR
                     PDVREAEQKLIATNASVGIAYTNMFPRLSLTAQYGVESEEFSDFFKSPIHYISGNLLTP
                     LFAMGKYRATLQAKKAAYEQECYSYEKSVLTAFKEARNAIVDFNKIKDIYESRLQLERS
                     SKATMELAQLQYINGVIGYLDVLDAQRSYFDAQIGLSNAIRDKQITLVKLYKALGGGW"
     CDS             complement(10788..13889)
                     /gene_functions="resistance (resist) RND_efflux (Score:
                     983.9; E-value: 6.8e-298)"
                     /gene_kind="resistance"
                     /locus_tag="ctg104_10"
                     /transl_table=11
                     /translation="MKVSFFIDRPVFSAVISILIVIVGIIGLTMLPIDQYPQITPPVVK
                     ISASYPGASALTVSQAVATPIEQELNGTPGMLYMESNSSNSGGFSATVTFDISADPDLA
                     AVEIQNRIKLAESRLPAEVIQNGISVEKQAASQLLTLCLTSTDPKFDEIYLSNFATLNV
                     LDLIRRIPGVGRVSNIGSRYYAMQIWVQPDKLANFGLTVADLQNALKDQNRESAAGVLG
                     QQPVQGLDVTIPITTQGRLSTVSQFEEIVVRANADGSIIRLRDVARISLEAQSYNTESA
                     INKENAAVLAIYMLPGANAMEVAKSVKEAMEEISKNFPEGMSYEIPFDMTTYISESIHE
                     VYKTLFEALILVIIVVYLSLQSWRATVIPLVAVPISLIGTFGFMLIFGFSLNILTLLGL
                     VLAIGIVVDDAIVVVENVERIMEEEKLSPYQATKKAMEGLTGAIIATSLVLAAVFVPVS
                     FLGGITGQLYRQFTVTIVVSVLLSTVVALTLSPVMCSLILKPEDPNKKKNIIFRRINKW
                     LAIGNHKYVGLIKHIVKHPRRVLSTFGMVLIAILLIHRIIPTSFLPIEDQGYFKIELEL
                     PEGATLERTRIVTERAVEYLMENPAVEYVQSVAGSSPRVGTSQARSELTIILKPWEERD
                     SQTIDDIMAQVKKDMSQYPECKVYLSTPPVIPGLGSSGGFEMQLEARGDATFENLVQAT
                     DTLMFYASKRKELSGLSSALQADIPQLYFDVDRDKVKFAGVPLADVFSTMKAYTGSVYV
                     NDFNMFNRIYRVYIQAEAPYREHKENINLFFVRGTDNAMIPLTSLGTTSYTTGPGSIKR
                     FNMFNSSVIRGEAADGYSSGQAMEIIEQIAREHLPENIGVEWSGLSFQEKQAGGQTGMV
                     LALVFMFVFLFLAALYESWMVPVAVLLSLPVAALGAYLGVWGCGLENDVYFQIGLVMLV
                     GLAAKNAILIVEFAKEQVDRGIDVVQAALHASQLRFRPILMTSLAFILGMLPMVIASGP
                     GSASRQAIGTGVFFGMIFAVTVGILLVPFFFVLIYKMKAKMKQK"
     CDS             complement(13956..15155)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Biotin_lipoyl_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg104_11"
                     /sec_met_domain="Biotin_lipoyl_2 (E-value: 4.5e-09,
                     bitscore: 25.7, seeds: 52, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLFFTHKEIALKKKRTALVVIGIGLVIGIYLIVSHQPAKMPELP
                     VVAIAPATQDDVEIYGEYVGRVRAQQFVEVRARVEGYLEQMLFAEGTYVTKNQVLFVIN
                     QDQYRAKADKARAQLKKDEAQAQKAKRDLERIRPLYEQNAASQLDLDNATAAYETAEAS
                     VAMSSADLDQAELELGYTIVRSPLAGHISERHVDLGTLVGPGGKSLLATVVKSDTVLVD
                     FSMTALDYLKSKERNVNLGQKDSTRSWQPNVSITLADNTIYPYKGLVDFAEPQVDPRTG
                     TFSVRAEMPNPERVLLPGQFTKVKLLLDVRESATVVPLKSVIIEKGGAYIYVMRKDSTV
                     ERRFIELGPEFQNQVVVERGLAPGEDIVIEGYHKLNPGMKVKVSPAVEDKKTEEEDTIG
                     "
ORIGIN
        1 aataaaagct atatgggtta cagtgtccat tattttatag atgttcctgt gattggcaac
       61 tttagtattc agcctgctat tggactttct atgaaaggta tcacttatga atatgataaa
      121 tttactacta aaaaatcgca tcgggtcgat ttggattctt ataagaaata tgatgtgaca
      181 gaatctcgcg gcactagtgt cactcaaaaa cataatctgg gctatttgga cgttcctatt
      241 ttatttgctt atgctttacc tttgtcagaa tcgtttaggg ttcagttggg agtgggccct
      301 tacttctctt atgggttgtt tggtaagttt aaatatgagt cggatacata tttgacagta
      361 tcccccgaca aatatggaga aaataaacat accataacca aagatgattg tccctccttt
      421 ggcaagaatg atgatgggga cgatcctaaa ggtaatatta accgttttga ctggggaatt
      481 gccatacagg gcagcatcta ttggaagcgc ttgtttttga atgttgctta tcaaaaaggt
      541 ctgaaatcgg ctaatattac tgacgagaag aatgaaggga aagataaatt ggctctttcc
      601 aatttgtcgt tagggttagg ctttatattt taatttgtga acagactgca ggaactgttg
      661 gaaaatagaa agatagaggg gcttcagaaa tttgatgaaa ctcgtgcatc ctttcttgct
      721 gaaatgaaga atctgtcggg tgaaatggag gttcacttgg aaactcattt tcttgttttt
      781 agagataaag cggtgtgaat ttgatgttcc atcgcttttc ctatgctatt ggaatgagct
      841 ctgattagct tgcccgataa gttatggaaa agggaatttg gtttcggggt cagtcattat
      901 agcaagcagg tggcaggata tttttttaca cgtacatacg tatgtgtaga aatctgtttc
      961 cggtcacagt cccgtatcgt tccgaaagcc tttattcttt tcggaaaaaa caaggatgtt
     1021 tgcaaaaaag atgaagacgt ctgataaaaa gaacaagacg tttcgtttca aagatctata
     1081 tcttccaacc tttagtttaa gtctttccgg ctatcggttt atccttctcc tccgaaaggg
     1141 aaggatgctg ggtgtaacgg caaaacttgg tacaggattt cgtggaactt gctgcaggat
     1201 ccgacagaac ttgtatcaag attctgaata ctttggcaag gaaagtcgtt gtttcgaggc
     1261 tgcacaagtt taccgtgttc accgtacaag cctatcgtgt tcattgcaca ggcttgtcct
     1321 gtctggtgga caaacaaagt aggtttgtac catgtaacaa ggtggataaa gtggtggcag
     1381 taggcatttt tgtacataaa ataatgtgct gccaccacct ctctaacttc ctgtttatag
     1441 gggttgcagg gaataggtga caacagtgac agcagaatta taaaactctg ttgtaggaaa
     1501 aagtgagaca attggagacg atccctctgt acaacgtaca ttatctttta ttttctttcc
     1561 ccggataatt aggtccataa agcatggtct tctccttgac caccaatcga ccgtccttca
     1621 cgaactcttc gccgcgttca cttaaatgac ggatcatttc attacgcatt tccgtcagct
     1681 gcttcctgta ttttttgtca ttgacggcat tgtgcaattc ctgagggtct tgggttaagt
     1741 cgaataactc ttcggtaccg gtgtggatac gccatatata ttttattttg ccgtcagtca
     1801 gtgcgcacca atagttgtca tcactgtaac aggtggcatg ttctagatcc agatacttgc
     1861 gccaggttgt ttccatgcct ttggcaagtg gcaacaaaga acggccgtcc atgtcagtgg
     1921 ggatggtcac atcggctgca tcaaggaaag tgggaagaat atcacgtaac tctacaggag
     1981 cgtctgtttt tcccggtgta acgtggtcga cggaaggcca tttcacgatg tatggcacat
     2041 gagtggagcc ctcgtatgga taagtctttc tccagtgata atggtcgccc atcatatcgc
     2101 catgatcgga aatgaaaacg attaatgcgt cattatacat atccttttct ttcaatgttt
     2161 ggataattct gcctatctgt tcgtcaatga aagtgatgtt ggcataataa tgacgtctgg
     2221 aattgcgtgc atattcattg ccaaaattac cgtatggagc gtcttgtgcc gtcttttcag
     2281 gatttagttt ttttgcgtat ttgccacacc agtctccgat agcaggatcg ggtattaggg
     2341 catcctcata catgtccaga tatctttgtg gtggatcata cggactgtgt ggacgggcaa
     2401 aagaaacttt cagaaataac ggtttgttgg tcggatcgta gttgctgata agttcacagg
     2461 ccatttctcc tgtccaatag gtaggatgga ggttttcggg caatttatat atacttgccg
     2521 tatggtcgtt ccagcctata ccggtggcgt caggattctt tccgggagct tttgtttgga
     2581 accattggcg gtaatcactg gtgaagttct cgtcttccac gcgtccgctt tcatctagca
     2641 gagtgccttc gaaaccatgt tttacccgtt ggggatgcca gtgcattttc ccgattccaa
     2701 aagtataata accagcgtct tttagcatct gtggcatttc gtatttatat tcgggagata
     2761 cttttccata tcccaacaag ccatgatgcc aaggagaaag tccggtcagc agaccagcac
     2821 gtgccggagt gctgcttgga caagaagaat agccattcat aaataatgtt ccctcggcag
     2881 ctagtgcgtc taggttaggg gagataacag catcgtttcc catacagcct atggcatcgg
     2941 ctcgctgttg gtctgtcatt atcagtatga tatgaggatg gttttgtgcg tatgcaaaag
     3001 aggagcacag tccggctgtg acagccaatg tgtatttcag gttggttaga gtattcatgt
     3061 ttataggttt ttcataatgt tatgtggcaa aggtaggaaa tttttggtaa ccttaagcca
     3121 taaatagtga tggtaaaagt agaaatattt gaaattgagg tcttattttg tgcatacgta
     3181 tgcgtggcct catatatact aatggtagaa aaaggttata aaaaaggctt gttcatgaag
     3241 aacaagcctt ttttatatgc atgtattaga aattattcac tccaattcat tgcttccata
     3301 cgtttgtaag aagcataacg tttcttggcc atttcttcgc aagcagcaaa cagatcagca
     3361 gcttcagcag gatactgctt cattacagag gcaaaacgaa cttcgttctt caagaaatcc
     3421 tggaaacctt cccatttcgg ttctttagag tcaagcatga atggattctt gccttcttct
     3481 tccaaagcag ggttgaaacg ccataagtgc cagtaaccgc attctacagc cttagcctct
     3541 tcagcctggc tcttacccat acctgccttc aaaccgtggt tgatacacgg agcgtaagcg
     3601 ataaccaatg acggaccggg ataagcttct gcttcacgga tagctttcaa agtctgagct
     3661 tggtcagcac ccatagcaat ctgggcaaca tatacataac cgtaagtagt agcgatcata
     3721 ccaaggtctt tcttacgtac acgcttacct gaagcggcaa acttagcgat agcacccagc
     3781 ggagtagcct tagatgactg accaccagta ttagagtaaa cttcagtatc caataccaaa
     3841 atatttacat cttcgccgga agcaatcaca tggtccaaac caccgtaacc gatatcgtaa
     3901 gaagcaccgt caccaccgat aatccattgg ctcttcttaa ccagatagtt cttgaatttt
     3961 gcaatggtag cgcagttctt acatttatct ttagcagctt ccaccattgg aatgatcttt
     4021 tcggcagcgg ctttgctctt gtctgcatcg tccttaccat caatccattc ctggaatgct
     4081 tctttgtatt ctgctggaca agtatcactg gcgatagcat ccttcatagc agcttcgata
     4141 cgtgcacgaa gtttcttgtc agccaaagtc atacccaaac cgaattcgca gaaatcttcg
     4201 aacaatgagt tagcccaagc aggaccttga cccttttcgt tcttagtata aggagttgaa
     4261 ggaacagaac cagagtagat agaagaacat ccggtagcgt tagcaaccat ttcacggtca
     4321 ccgaataact gggaaatcag tttcacatat ggagtttcac cacaacctga acaagctcca
     4381 gagaattcga acaacggagt agcgaactga gagttcttca cattggcttt gatatctact
     4441 aaatgttgtt tgctcttcac gttcttagcg cagtattccc aattggctgc ttgagacaac
     4501 tggctttcca aatgtttcat tgtaagagcc ttgcctccct tcttcggatt gcccggacaa
     4561 acatcagcac agttaccaca acccagacag tcaagcacgt caacctggat acggaatgtc
     4621 attccgtcaa attgtttacc tacagctttc aatgtctcga agtttgcacc cttttgttct
     4681 tcagcgtcaa gtacgaacgg acggatagaa gcatgaggac aaacatatgc acacttgtta
     4741 cactggatac agttttcagc attccattca ggtacgaatg cagctacacc acgtttttcg
     4801 tattgagcag taccttgttc ccaagtaccg tcttcgatgc ctttgaatgc agataccggc
     4861 aacaagtcac catcctgagc gttgatagga cgaactactt cgttgatgaa tgcagggtca
     4921 ttgttagcag caggagcttc aacttccaga ttagcccaag ccggatcaac agccaattgt
     4981 ttgtattcgc caccacggtc tacggcagca tagttcttgt tcaccacgtc ttcgcccttc
     5041 ttgccataag acttaacgat gaatttcttc atctgttcta cagccaagtc aacaggaata
     5101 acgcctgtga tacggaagaa tgctgattgc aggatggtat tggtacggtt gcccaaaccg
     5161 atttcctgag caatctgagt tgcattgata tagtaaacag taatgttgtt ttgtgcgaaa
     5221 tatttcttaa ccttgttcgg taagttcttg gccagttctt caccttccca aatagtgttc
     5281 aacaagaaag aaccgttctt acgtaaacca cgagttacat cgtacatgtg caaataagct
     5341 tgtacgtggc aagctacgaa gttcggagta tttactaaat aagtagaacg gataggagta
     5401 tcgccgaaac ggaggtgaga gcaagtgaaa ccaccagatt tcttagagtc gtatgagaaa
     5461 taagcctgac agtgcttgtc ggtgttgtca ccgataattt tcactgagtt cttgttagca
     5521 cctacagtac cgtcagcacc taatccgtag aatttagctt caaacatacc ttcgccgcct
     5581 aatgcgattt cttcttcttg aggaagagaa gtgaaagtta catcgtctac gatacccaca
     5641 gtgaagtggt ttttcggcat tggcagagcc aaattcttga atacagcgat gatttgagca
     5701 ggagtagtgt ctttagaacc taaaccgtaa cgtccaccta cgataaccgg agcgttttct
     5761 gttccataga agcagtcttt aacatccaga tacaaaggtt cgccgtttgc tcccggttct
     5821 ttagtacggt caagaactgc gatagtcttg gcagtcttag gtacagcagc caagaaatgt
     5881 ttagcagaga acggacggta taaatgtaca gaaaccaaac ctactttttc acctttgctc
     5941 atcaagtagt cgatagcttc gcgggcagct tctgtaacag aacccattgc gataattacg
     6001 cgttcagcgt cttcagcacc atagtaatcg aacaaaccat gaggacggcc tgtgattttg
     6061 ctgatttcgt tcatgtattc ttctacgata gccggaactg cttcatagaa gttattgcaa
     6121 gattctctgt gctggaagaa gtggtcgggg ttttcagcca taccgcgtgc aacagggttg
     6181 ttaggattca acgcgcgttc acggaattct gccaaagcct gttgatcaat cagacctgcc
     6241 agatcttcat tctccagcat ttcaattttt tggatttcgt gagaagtacg gaaaccatcg
     6301 aagaagttga cgaatggcac gcgagatttg atagtagcaa gatgagctac agcagccata
     6361 tccataactt cttgtacaga accttcgcac aacatggcga aacctgtttg gcggcaagac
     6421 atgacgtcct gatggtcacc aaagatacac aatgcgtgtg aagccaatgt acgagccgat
     6481 acgtggaata cgcaaggcag gaattcaccg gcaattttgt acatgttagg gatcatcagc
     6541 aacagaccct gagatgcagt gtaagtggta gtcaacgcac ctgcctgaag agaaccatga
     6601 acagcacctg ctgcaccgcc ttctgactgc atttcttgta ccaaaactgt ttcgccgaat
     6661 atgtttttac gacctgcggc agcccattcg tctacgtatt cagccatagt agacgacgga
     6721 gtgatgggat agatagcagc tacttcagag aacatatacg agatatgtgc tgctgcctgg
     6781 ttaccatcac aagtgatgaa ttttttttgt ttagtcatac aattactaat tattaggtaa
     6841 taaaatctat tctctatctc ttaatataaa aagccgaaaa gccataatgg gatcatattt
     6901 ccgtgtccta attccaattt gtgtagggca taatacacgt ttggattatt tttgaacttg
     6961 cacccttctg cgcaaatacg gaaatgcagt ccgttgtcta ccataaatga agtgccttta
     7021 tcgcctttat atagtttatg gtccttatac agggtattca tgaaaaatgt atccagtaca
     7081 tcctgttctt cgacctttac cggataaatg gagtacatca ggttggtgtt gtgcatcatc
     7141 agtttggaag gtttcttggg aaattcctct cccttgggat aaaccatatt gataagacgc
     7201 gcatctgcca gatacttaat gtaattcatc accgtggcac gtgaagtttg aatctccgtg
     7261 gccagctggc tgacgttcgg agcaacgggt ccgtccacag ctagcaaata tagtaatttt
     7321 tttatctttg aaagatattt cagctcaatt tgtttgataa gaagtatatc tacttctatc
     7381 atcatattca tggtttttag cagattctcc gaaaagttac gtttttccag gaagaatggg
     7441 tagaaaccgt gatgcagata gtcttgaaaa taatccaagg gcttcacgtt gcgcaggatg
     7501 gttttcgcta tctgttcgtg attctccaaa atttcttgta aggtataggc acggaaacaa
     7561 ttgccgcttt gcaaattcag atattcgcgg aatgagaaac ctctcaggta gtataccttg
     7621 acaatgccgc tcagttctgg attttcttct ttcagtcgca tcacggatga tccggtgaat
     7681 ataatcttca gagtaggaaa catttcatag caagcacgca ggtcgtggct ccattcggga
     7741 tacttaaaca cttggtctat caacaaaact tttcctcctc gttttacgaa ttctgcggca
     7801 aactccacta atgtatattt agagaagtaa aagttattca tgttgatgaa cagacatgag
     7861 tgatccgttc cgaacttttc ttttgcatat tgcaggagga aagtcgtttt ccctacgcca
     7921 cgagtaccct tgataccgat cagtctgtca ttccagtcta tctcgtccat caagtcccgg
     7981 cgaacaggag catttgtatg ttccaccaga taactgtgtg ttctgtaaaa ggtttccatg
     8041 gttgcttttt tatcggctgc aaatatagca atactaattc aaattgcaaa ctggagatag
     8101 caaaatatta tttttttttc tactaaaaga cggacaagag aaatggtttg tactctaaaa
     8161 catttatctt tgtgtccgga aatggaagcg ctttatttat tcaatccgga aaatgatatg
     8221 gcattagctt gtggtgatcc ttattatatg gcacctgcca gtgcacgacg aatggcggcc
     8281 gagctatcca tgttgcctgc atggtatgca gaagagggag gaactgtgtg gctggattct
     8341 gctcagcgta tgaaaacaat ggaaagacaa tcttttttgc cgctttcggt caattgggtt
     8401 ttagaattcg tacccattta taataaggtg attccttggg gatggaatcc gtctttggtg
     8461 cgtcgtttgc aggaagctgg atttcctgat acagcatatc cttcagtaga gcgtatgaag
     8521 cgtatccgtc aaatatccgg acgtcagacg gctgtaaaag tgttacgccg cctttgtaga
     8581 catataggtg ggaatattcc catattgggg gaggcttttg tattgtcgtc aacagaggaa
     8641 gtgaaggctt ttgtgttgtc tcattctcgt gctttgttaa aagcgccatg gtctggtagt
     8701 ggaagaggga tacaatatgt ttcaggtagt tttcccatcc ctctggaagg gtggattcga
     8761 cacatactta ccactcagca tgaggtgata ggagaacctt tttatgataa gcttttggat
     8821 tttgccatgg agttttttgc agacgagtgg ggacaggtac attttatagg gtattcctta
     8881 tttgaaacgg ataagagagg tgtttataaa gaaaacttgt tggcggcgga tcgggttatt
     8941 gaagcgagga tatccactta tgtttctgcg gaaatcttac atcaggttgg gagggcgtta
     9001 caggtagagt tggcagaggt gataaaaggg agttacgaag gctatctggg ggtggatatg
     9061 atgatatgcc gtacccaaaa tagcgggtat gccattcatc cgtgtgtgga aataaatctt
     9121 cgtatgaata tgggagtggt agcacgcttg atatatgata actatgtgtg tgatggcgtg
     9181 cagggacggt atgttataga atattatgca aagcctggtg aggcatggca ttctcatctt
     9241 gcgcttcaag aaaagtatcc tttatatctg gagaatggaa aagtgaagtc gggttatttg
     9301 tcacttacac cggtagagaa caatacgtcc tatcaggcat atatcttaat ttgattttcc
     9361 ggataaagga agatacagaa aagaggggat ggttaccatc caccccctaa tgctttatac
     9421 aattttacta atgtaatctg tttgtctctt attgcattgc ttaatcctat ttgtgcgtcg
     9481 aaatagctac gttgtgcatc caatacatct agatagccta ttactccatt gatgtattgc
     9541 aattgggcca gttccattgt tgctttagag gaacgttcca gttgcaggcg cgattcgtag
     9601 atatctttta tcttattgaa gtccacaatg gcattgcggg cctctttgaa tgcagtcagc
     9661 actgattttt catagctgta gcattcctgt tcgtatgcgg cttttttggc ctgtagggtt
     9721 gctctgtatt ttcccatggc gaagagagga gttagaagat tgccactgat ataatgaatg
     9781 ggcgatttga agaaatcaga gaattcttca ctttctacgc catattgtgc tgtgaggcta
     9841 agtcgtggga acatattggt ataggcaata cctacactgg cattggttgc tattaatttc
     9901 tgttctgctt cacgtacatc gggacgacgt tccagcagag tggagggtag acctactggt
     9961 aatgtttcag gtagttttac ttcttcgggt agaatggaac gctgtatgcg gtgcgggtat
    10021 tcgcctgcta aaaatgcaat atcattttct ttcaatgaaa ttttcctttc tagttcagga
    10081 actaaagttg cggtacgtgc atactccact tgtgcctgtt gataagaagt ttctgaagtt
    10141 agtcctcctt caaaacgaag ttttgccaag cgtactcctt ctttacgggc atagagtgtt
    10201 tgacgaacaa tgttcagctc attgtctaat gcgaccaatt caaaataggc ttgtgccact
    10261 tcggacacaa tactcatttt caaggcacgt tgcgcctcga tgcttcccag gaattgtgct
    10321 atgcttttgt cttttgccca acgcaggtta ccccataggt ctaattccca agttacggta
    10381 agtttaccac ccagttcggg gtcattttta tagttgttac caccataatt acttccttct
    10441 ttttgagcat aagcgcctcc gttcagttgg gggaaaaggt tggcaaagtc tatgcgcttc
    10501 attgcggcaa gttcttttac acgtgccgca gcaattttca tgtctttgtt gttatccaac
    10561 gttttttcta tcaagctttg caaggttgtg tccgtataga tttcccacca ctgcatatcg
    10621 gcaatagata atgtatcctg ttgtcgtagc gtatctaatt gttggggcag atgcaagtcg
    10681 ggacgtgtgt agtgcttacc taattggcaa gaagtcagca aagtcattcc tgatacggct
    10741 atatataata atgtatgttt catcatttct ttcgtctttt tatatcctta tttttgtttc
    10801 attttcgctt tcatcttgta tatcagtaca aagaagaaag gtactaacaa aattcccaca
    10861 gttacagcaa agatcattcc gaagaataca cctgtaccaa tagcttgacg gctggctgaa
    10921 cctggcccgc tggcgataac cataggtaac atacctaaga tgaatgccaa tgaagtcatc
    10981 aaaataggtc gaaagcggag ttgtgaagca tggagtgcag cttgtaccac atctattcct
    11041 ctgtccactt gttctttggc aaactctaca ataagaattg catttttggc ggccagtcct
    11101 accaacatca ccaatccgat ctggaaatag acatcattct ccaacccaca gccccataca
    11161 cctagatagg cacctaatgc ggctacaggt aaagagagta atactgcaac cggtaccatc
    11221 cagctttcgt ataaggcagc aaggaacaaa aacacgaaca tgaacactaa tgccagcacc
    11281 ataccggtct gtccacctgc ttgtttttcc tggaaagata gtccgctcca ttctacaccg
    11341 atattttctg gtaggtgttc gcgagctatt tgttcgataa tttccatggc ctgtcctgaa
    11401 ctgtaaccat ctgcggcctc accgcgaatc acagaactgt tgaacatatt aaaacgtttg
    11461 atgctgcccg gacctgtggt atacgaagtg gtacccaacg aggtgagcgg tatcatggca
    11521 ttgtctgtac cccgtacaaa aaataggttg atattctcct tgtgttcccg gtagggtgct
    11581 tctgcttgaa tatatacacg gtagatacga ttaaacatat tgaaatcgtt tacatatacc
    11641 gaacctgtat aagctttcat ggtcgagaat acatctgcta aaggtactcc tgcgaatttt
    11701 actttgtcac ggtctacatc gaaataaagt tgggggatgt ccgcttgtaa agccgaggat
    11761 aaacctgata attccttacg ttttgatgca taaaacatca atgtatccgt agcttgtacc
    11821 aaattttcaa aagtggcatc tccacgtgct tccagttgca tttcgaaacc acccgaactg
    11881 cccaatcccg gaataacggg aggggtggaa agatatacct tgcattcggg gtattgcgac
    11941 atgtcttttt ttacctgtgc cataatatcg tcaatagttt gcgagtcacg ttcctcccaa
    12001 ggttttaaga tgatagtcag ttcacttcgt gcctgactgg tccctacacg cggactgctt
    12061 cctgccacgc tttgtacata ttccactgcc ggattttcca tcaggtattc cacagcacgt
    12121 tccgtcacga tacgtgtacg ttccaacgtt gcaccttcgg gcagttccaa ctctatttta
    12181 aaatatcctt ggtcttcgat ggggaggaag ctggtgggaa taatgcgatg gattaacagg
    12241 atggcgatca ataccatgcc gaatgtgctc agtacccgac gcgggtgttt cacaatgtgc
    12301 ttgatgagtc ctacatattt atgattgccg atagccagcc acttattgat acggcggaat
    12361 atgatattct ttttcttgtt cggatcttcc ggtttcagaa taagtgaaca catgactgga
    12421 ctcagtgtca aagctactac cgtagacagt aatacagata ctacgatggt taccgtaaac
    12481 tggcgataaa gttgtccggt aattccacct agaaaactta cgggaacaaa tactgctgcc
    12541 agtaccaaag aagtggcgat aatggctcct gtaagtcctt ccatagcttt cttggtagct
    12601 tggtagggag atagtttctc ctcttccatg atacgctcca cattctctac taccacgata
    12661 gcatcgtcca ccacaatacc gatggcaagt accaatccca acagggtcag gatattaagc
    12721 gagaatccga aaatcaacat aaatccaaaa gttccaatca gtgagatagg tacggcaact
    12781 agtgggataa ctgttgcacg ccagctttgg agtgaaaggt atactacgat gataaccagt
    12841 atcagggctt caaacagtgt tttgtacact tcatgaatgg attccgaaat atacgtagtc
    12901 atatcgaaag gtatctcgta actcattcct tcgggaaaat tcttgctgat ttcctccata
    12961 gcttctttca cgctttttgc tacttccata gcgttggctc ctggtaacat atagatggcc
    13021 aataccgctg cattttcttt gttgatggca ctctcggtat tgtatgattg tgcttcgagt
    13081 gagatgcggg ccacatcacg taaacggatg atggaaccat cggcattagc acggactacg
    13141 atttcctcaa actggcttac ggtagataga cgtccctgag tagtgatggg aatggttacg
    13201 tctaatcctt gtacgggttg ttgtcccagt acaccggctg ctgattctcg attttggtct
    13261 tttagtgcat tctgcaagtc ggctacagtc agaccgaaat tggccagttt gtcgggttgt
    13321 acccagattt gcatggcata atatcggctt ccgatgtttg aaacacgtcc tacgccaggg
    13381 atacggcgga ttaggtccag cacattcaga gtggcaaagt tgctaaggta tatttcatcg
    13441 aacttcgggt cggtagaggt aaggcatagg gtcagcaatt gactggcagc ctgtttctct
    13501 accgaaatac cattttgtat aacttctgct gggaggcgtg attctgctaa cttgatacgg
    13561 ttctgtattt ccactgccgc tagatcggga tctgccgaga tatcaaaagt gacggtggct
    13621 gaaaaacctc ccgaattgga actatttgat tccatgtaaa gcattcctgg ggtaccgttc
    13681 aattcctgct ctataggagt ggctacagcc tgtgatactg tcagggcact ggcacccgga
    13741 taggatgcgc tgattttcac taccggcgga gtaatctgcg gatattggtc aatgggtagc
    13801 atcgtgagac cgatgatacc gacaatgact attaatatgg agatgacagc tgaaaatacc
    13861 ggtctgtcta taaagaaact aactttcata atgtctattg tttttttgaa tgcgtaaatt
    13921 ttcctccata ggggaattcg tattcgggag tgaaattatc cgatcgtatc ttcttcctcc
    13981 gtttttttgt cctctacggc aggacttact ttcactttca tgcctggatt cagcttgtgg
    14041 tatccttcta tgacaatgtc ttctccgggg gccaagcctc tttccaccac tacttgattt
    14101 tggaattcag gacctaattc aatgaaacgt ctctctactg tagaatcttt gcgcattaca
    14161 taaatatagg cgccgccttt ttctatgata acggacttta acgggactac cgtagcactc
    14221 tctctgacat ccaataatag ttttactttg gtgaactgcc caggaagtaa tacccgttct
    14281 ggattcggca tttcggcacg tacggagaat gtacctgtgc gtggatcaac ttgcggttcg
    14341 gcaaagtcta ctagtccttt gtatggataa atagtattat ctgccaaagt aatggataca
    14401 ttgggttgcc aggagcgggt ggagtctttt tgacctaagt tcacattacg ttctttactt
    14461 ttcagatagt ctagagcagt catgctgaaa tccactaata cagtatcact ttttactacg
    14521 gtagcaagca atgatttgcc acccggaccg actaatgttc ctaaatctac gtgacgttca
    14581 ctgatatgcc ctgctaatgg agaacgaact atagtataac ctagttccag ttctgcttga
    14641 tcaagatcgg cactactcat agctaccgac gcttctgctg tttcatatgc agcagtagca
    14701 ttgtccaagt ccaactggct ggcagcgttt tgttcatata gcggacggat acgttctaag
    14761 tcgcgttttg ctttttgtgc ttgtgcctca tcctttttca attgggcgcg cgctttgtca
    14821 gctttggccc gatattgatc ttgattgata acaaacagca cttgattttt agtgacatat
    14881 gtaccttctg cgaaaagcat ttgttctaaa tatccctcta ctcgggcacg tacttcaacg
    14941 aattgctgtg cacgtacgcg tcctacatat tcaccatata tttccacatc gtcttgcgtt
    15001 gctggtgcta tggcaactac tggaagttcc ggcatctttg ccggttgatg ggaaacaatc
    15061 aggtaaatcc cgataactag tccaatacct attactacaa gcgctgttct tttctttttt
    15121 agcgcaattt ctttgtgtgt aaaaaatagt ttcatacttt agttttgtta ttgtttaaga
    15181 tgccatcagt agaaatacaa gcagcgtgcc aaactattgt aaatagtctt tcctattcat
    15241 aatcagtgct ttatttctgt ctttggttga tagggaaagt gtggaaaata ggcaacagct
    15301 gtagaataat tccacagtag gcgtaattaa atttagtaga ggattatcga tttggatgca
    15361 aaaatagtaa aatagtgggt aatcttaaaa tatttattca ctattcatta taatgaggaa
    15421 gatgttatag tgttagcaga tatgtatgca atttaaattt tgcttgagat cgtcgtatct
    15481 gcaaccttat tgttttgaaa acacgccccc tttcattttg aaaagggttg tgtttttctt
    15541 ttttatgact gaatatggta tctgtttgtt tatcaggaga ttatagtctt ctttttcatt
    15601 ttggcatagt attcgctata tacttgtcaa atataaaagg tataaaaaga tggg
//
