LOCUS       c00145_gnlPro..         9973 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FGBGCNEI_145.
ACCESSION   c00145_gnlPro..
VERSION     c00145_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 18:09:10
            Original ID  :: gnl|Prokka|FGBGCNEI_145
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 9973
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..9973
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[931:6919]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      932..6919
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..9973
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..9973
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             147..521
                     /locus_tag="ctg145_1"
                     /transl_table=11
                     /translation="MKRLVLLVVVALGMSATSFAGEKVEGKDWKVDVNVAKLSKYLNLD
                     ARQMEEVANISDYFADKVQSASYAKEAKQGKKLREAVYGNFKLMKRTLTNEQYKKYVQL
                     LNVTLKNKGLDSYMEDVANK"
     CDS             932..2734
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg145_2"
                     /sec_met_domain="ILVD_EDD (E-value: 1.6e-217, bitscore:
                     712.4, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNQLRSSFSTQGRRMAGARALWVANGMKKEMMGKPIIAIVNSFT
                     QFVPGHTHLHEIGQQVKVEIEKLGCFAAEFNTIAIDDGIAMGHDGMLYSLPSRDIIADS
                     VEYMVNAHKADAMVCISNCDKITPGMLMAAMRLNIPAVFVSGGPMEAGEWNNQHLDLID
                     AMIKSADASVSDEDVAQIENNACPGCGCCSGMFTANSMNCLNEAIGLGLPGNGTILATH
                     ANRTQLFKDAAALIVKNAYKYYEEGDDSVLPRNIATRDAFLNAMTLDIAMGGSTNTVLH
                     LLAIAHEAEVDFKMDDIDMLSRHVPCLCKVAPNTQKYHIQDVNRAGGILNILGELSKGG
                     LLKTDVKRVDGLTLAEAVEKYNICKKEVDTEAKRIYSSAPGNKFNIKLGSQNAVYKELD
                     TDRANGCIRDLQHAYSKDGGLAVLKGNIAQDGCVVKTAGVDESIWKFSGPAKVFDSQDA
                     ACEGILGGKVVSGDVVVITHEGPKGGPGMQEMLYPTSYIKSKHLGKECALITDGRFSGG
                     TSGLSIGHISPEAAAGGNIGKIVDGDIIEIDIPNRSINVKLSDEELAARPMTPVTRDRK
                     VPKSLKAYASMVSSADKGGVRIID"
     CDS             2836..4533
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg145_3"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.1e-49, bitscore:
                     156.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKEKITGAEAMMRSLEYQGVKTLFGYPGGSIMPTFDALYHHRNT
                     LNHILVRHEQGAAHAAQGFARVSGEVGVCLVTSGPGATNTITGIADAMIDSTPIVVIAG
                     QVGASFLGTDAFQEVDLVGITQPITKWSYQIRRAEDVAWAVARAFYIAKSGRPGPVVLD
                     FAKNAQVEMVDYEPMKLDFIRSYDPEPNPDKESLQEAAELINNAQRPLVLVGQGVELGN
                     AQNELRAFIEKADMPCGCTLLGLSAIPTSHPLNKGMLGMHGNLGPNVKTNECDVLIAVG
                     MRFDDRVTGKLDTYAKQAKVIHLDIDHSEIDKNVKVDVPVLGNCKYTLTMLTQLIRKNE
                     HSEWIDSFTEYEKTEYEHVISKEIHPVDGALNMGEVVRAVSEASNNEAVLVTDVGQNQM
                     MAARYFKYSKNRSIVTSGGLGTMGFGLPAAIGATFGRPDRTVCVFMGDGGLQMNIQELG
                     TIMEQKAPVKIILLNNNYLGNVRQWQAMFFGHRYSFTPMLNPDYMKIAEAYEIPARRVM
                     KREELQAAIHEMLTTDGPFLLEACVIEEGNVLPMTPPGGSVNQMLLEC"
     CDS             4544..5098
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg145_4"
                     /sec_met_domain="ALS_ss_C (E-value: 1.1e-19, bitscore:
                     59.8, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKTLYTLIVHSENIAGLLNQITAVFTRRQINIESLNVSASSIKG
                     VHKYTITAWTTQDVIEKVVKQIEKKIDVLQAHYFTDSEIYQHEIALYKVSTPEFQENPM
                     ASKVIRRYSARIVEVNPVFSIVEKNGMSEEITALYEELRGLGCVLQFVRSGRVAITTSC
                     FERVNEYLTQREEKYRQQKTE"
     CDS             5098..5841
                     /locus_tag="ctg145_5"
                     /transl_table=11
                     /translation="MMSENKVGTYRFVAEPFHCDFSGKLTMSVLGNHLLNCAGFHAADR
                     GFGIATLNENHYTWVLSRLAVELENMPCQYEGFSIQTWVENVYRLFTDRNFAILDKEGK
                     TVGYARSVWAMISMETRKPADLLTLHGGSIIDYVCDKKCPISKPGRIKVTEKAPVSEYQ
                     TRYSDIDINGHVNSIKYIEHILDLFPIEFFKEKRIKRFEMAYVAESYYGDILSFYREEV
                     EEKEYDIEVKKNGTDVVVRSKVIFI"
     CDS             5876..6919
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg145_6"
                     /sec_met_domain="IlvN (E-value: 9e-47, bitscore: 148.0,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 1e-41, bitscore: 131.9,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQLNFGGVTETVVIRDEFPLEKAREVLKDETIAVIGYGVQGPGQ
                     SLNLRDNGFNVIVGQRPGKTYEKAVADGWVPGETLFGIEEACQKATIVMCLLSDAAVMS
                     VWPTIKPYLTQGKALYFSHGFAITWSDRTGVVPPTDIDVIMVAPKGSGTSLRTMFLEGR
                     GLNSSYAIYQDVTGKAYERTIALGIGIGSGYLFETTFQREATSDLTGERGSLMGAIQGL
                     LLAQYEVLRENGHSPSEAFNETVEELTQSLMPLFAKNGMDWMYANCSTTAQRGALDWMT
                     PFHDAIKPVVEKLYHSVKTGNEAQISIDSNSKPDYREKLEEELKALRESEMWQTAVTVR
                     KLRPENN"
     CDS             7047..8132
                     /locus_tag="ctg145_7"
                     /transl_table=11
                     /translation="MNNRLSLLLIGCIFPFLSFYAQKNMNLPPYYPTVKGITDYAVWQL
                     VYPDSLLRANIAGEAVCTLRIDSLGTVRCKYIEATHPLFAKAAEDVIEGMREWQPAKKA
                     GRDIDTTIVFHIPFNPDVYSDRIWRQQQVLESCRGQLVDSMPVFPDDIRSLVMGNMSWP
                     DDKVDKAVAICRFTVNEKGEIVDIRVIKGTHPAFDKESIRILSNFPRLIPAMKNRKSVP
                     YDYFLTMRFWKEDLEHYLLYRECAQEDLEKITWEPYRYSSYPGGTVALTQFINSHLKIT
                     PEMKATGKQGRVIYSFNVDIDGSMKDFQLVRGLDPLMDAEALRVLQLVNERWSTGYYFN
                     SKKWYREFYVNQFTIPIIFSW"
     CDS             complement(8226..9440)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OAD_beta"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg145_8"
                     /sec_met_domain="OAD_beta (E-value: 1.1e-112, bitscore:
                     365.7, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENIDFGILFQGIGTMIESGWFLACARVFLILLGFLLIYLGWKGI
                     LEPIVMIPMGLGMIAINCGTLIMPDGNLGNLFLDPMLSDTDELMNTMQIDFLQPVYTLT
                     FSNGLIACFVFMGIGTLLDVGFLLQKPFASLFLALCGELGTFLTLPIANALGLSAQESA
                     SVAMVGGADGPMVLFTSLALAKHLFVPITVVAYLYLGLTYGGYPYLVKLLIPKRFRSIK
                     MTVKKAPKNYDAKVKLAFAAVLCAVLCFLFPVASPLFFSLFLGVAVRESGMKHIYDFVS
                     GPLLYGSTFMLGLLLGVLCDAHLLLDPKILKLLILGMLALLLSGIGGILGGYIMYYIKK
                     GNYNPVIGIAAVSCVPTTAKVAQKIVSKDNPDSFILGDALGANISGVITSAIITGIYIT
                     IIPLL"
     CDS             complement(9462..9971)
                     /locus_tag="ctg145_9"
                     /transl_table=11
                     /translation="DVNITITRNLILFYLLNHIYIIMLHLFLSTLAMMGLTFLIGFFVA
                     AIIKGIALAADSMDFYSSHLLELQRLRKIKKARARFIQLVWNNSPEEMEALGDSRENWN
                     RGMNSDLRGKQEGGYYHGVSHGASQLNLIDYYYPDTKMIYLKKREEMHNQQQKSTHVKK
                     NLSMNK"
ORIGIN
        1 atatatgaca acatgtcgta aagcatgttg ttatatttgc agtgtaaaga gaaagagata
       61 acgagattgt ttttaaaagg tattatttag ttcttaggta ctaaataaat tgtttttagg
      121 tttaacaaat taaaatttta ggtattatga aacgtttagt attgttggtt gtagtggcat
      181 taggaatgtc agctacaagt tttgcaggag aaaaagtaga aggtaaagat tggaaggtag
      241 atgttaacgt cgcaaagttg agcaaatatt tgaatttgga tgcacgtcag atggaggaag
      301 ttgctaatat ttctgattat tttgctgaca aagtacaaag cgcaagctac gcaaaagaag
      361 ctaaacaagg taaaaaattg cgtgaagccg tatatggaaa cttcaaactg atgaaacgta
      421 cattgacaaa tgagcagtac aagaagtatg tacagttgtt gaatgttaca ttgaaaaaca
      481 aggggttgga ttcctatatg gaagatgtgg cgaataagta aatttataaa atgaaataaa
      541 tgaactgaaa agagaatgca aaccaatgca ttctcttttt tatttatccg ttggaagata
      601 cagtgtatat ttgtgataaa atgatcgttt aaagctcgat ttagttacga ataataattt
      661 ataagaaaaa aaatcttcat tttatttgtt tgttacgaaa aacgccttac ctttgcagtc
      721 gttaaagaaa caaagaaaac agatatatga atattactac tctaaataac ctagcagtcc
      781 tgcatattat tcgcgtcgtg gtggtcacac taggagcgtg agaaaggttg tgtatgtgta
      841 gttgtacata taaagaaata attggaagcc tttctcacat ggtgaggaag gctttttcaa
      901 taagtatagg acgttataga tttagaataa gatgaagaat cagttacgca gttcgtttag
      961 cacacagggt cgccgtatgg caggagcgag agctttatgg gtggctaacg gcatgaaaaa
     1021 agaaatgatg ggcaagccca ttatagccat agtaaattcg tttacacagt ttgttccggg
     1081 acatacccat ctgcatgaaa taggtcagca ggtgaaagtt gagattgaaa aactgggatg
     1141 ttttgcagca gaattcaata cgattgccat tgatgacgga atagctatgg gacacgatgg
     1201 tatgctgtat tcactgccca gtcgtgatat cattgccgac agcgtggaat atatggtgaa
     1261 tgctcacaag gcggatgcaa tggtgtgtat cagtaattgt gacaaaatca ctccaggtat
     1321 gctgatggct gccatgcgac tgaacatacc ggctgttttt gtatcgggtg gtcctatgga
     1381 agcgggagaa tggaataacc agcatcttga tttgatagac gccatgatta aatctgctga
     1441 tgcatcggtc agcgatgagg atgtggctca aattgaaaat aatgcgtgtc ctggctgtgg
     1501 ttgctgttcg ggtatgttta cggctaattc catgaattgc ctcaatgagg ctattggtct
     1561 ggggcttccg gggaatggca ctattttggc gactcatgcc aaccgtactc agttgtttaa
     1621 agatgcggct gctctgatag tgaagaatgc ttataaatat tatgaggagg gagatgacag
     1681 cgtgttacca cgcaacattg ctactcgtga cgcttttctg aatgccatga cattggatat
     1741 tgcaatgggt ggttctacca atactgtgct ccatctttta gctatcgccc acgaggcgga
     1801 agtagatttc aagatggatg atattgatat gctttcacgc catgtgcctt gtttgtgtaa
     1861 agtagctccg aatacacaga aatatcatat ccaggatgtg aaccgtgccg gtggtatcct
     1921 taatatattg ggagaattat ccaagggtgg tttgctgaaa actgatgtga aacgagtgga
     1981 cggcctgaca ttggcggaag ctgtcgaaaa atataatata tgtaagaaag aagtggatac
     2041 tgaagcaaaa cgtatttatt caagtgctcc gggaaacaaa ttcaatataa agttaggttc
     2101 tcagaatgct gtttataaag aactggatac agatcgtgcc aatggttgta tccgcgattt
     2161 gcaacatgcc tatagtaaag atgggggttt ggccgttttg aaagggaaca ttgcacagga
     2221 tggttgcgta gtgaaaacgg ccggagtgga tgaaagtatt tggaaattct cggggcctgc
     2281 caaggtgttt gattcgcagg atgctgcttg tgaaggtatt ttaggaggaa aagtagtcag
     2341 cggagatgtt gttgttatca ctcatgaagg tccgaaaggt ggtcccggta tgcaggaaat
     2401 gctttatcct acttcttata tcaaatccaa gcatttagga aaagaatgtg ctttgattac
     2461 cgacggacgt tttagtggag gaacttcggg attaagcatc gggcatattt ctcccgaagc
     2521 tgcagcgggt ggtaatatcg gaaaaatagt ggatggtgat ataattgaaa tcgatattcc
     2581 gaatcgcagt atcaatgtga aactgagtga cgaagaattg gccgcccgac cgatgacacc
     2641 ggtgacccgt gaccgtaaag ttcctaaaag cttgaaggca tacgctagta tggtaagttc
     2701 tgcagataaa ggaggagtga gaatcattga ctaaattaga aattaaaaat tgagaataaa
     2761 aaaaatagat ttgttgtcat tggtcgattg tacggcatcg tatttttttg attctcaatt
     2821 ctcaactaaa caattatggc aaaagaaaag ataacaggag cagaggcgat gatgcgttct
     2881 ttggagtatc aaggagtgaa aactcttttc ggatatcccg gaggttctat catgcctact
     2941 tttgatgctt tatatcatca tagaaataca ttgaaccata tattggtccg tcatgaacaa
     3001 ggagctgccc atgcagcaca gggatttgcc cgcgtatccg gtgaggttgg tgtctgtttg
     3061 gtgactagcg ggcccggtgc gacaaatacc attactggca ttgccgatgc tatgattgac
     3121 agcacgccta tcgtggtgat tgccgggcag gtaggagctt cctttttagg tacggatgct
     3181 tttcaggaag tggatctggt gggcatcact cagcctatta ccaaatggag ttaccaaatt
     3241 cgtcgtgcgg aagatgtagc ttgggctgta gcccgtgctt tctatatagc taaaagcgga
     3301 cgtcccggtc ctgtcgtttt ggactttgcc aagaatgcac aagtggagat ggtggattat
     3361 gaaccgatga agcttgattt tatccgtagt tatgatccag aacctaatcc tgataaggaa
     3421 tctcttcagg aggctgccga attgataaac aatgctcaaa ggccattagt gttggtagga
     3481 cagggggtag agttaggtaa tgcgcaaaat gagttacgtg catttataga aaaagccgat
     3541 atgccttgtg gctgtacttt gctgggactt tcggctatac caacttcgca tcctttaaac
     3601 aaaggaatgt taggtatgca tggaaatctg gggcccaatg tcaaaactaa tgaatgtgat
     3661 gtgttgattg ctgtaggtat gcgctttgac gatcgtgtaa ctggaaaatt agatacatat
     3721 gctaaacagg caaaggtgat tcatttggat attgaccatt ctgaaataga taagaatgta
     3781 aaagtggatg tacccgtatt aggtaattgt aaatatacgc taactatgct gacgcaactt
     3841 atccggaaga atgaacattc cgaatggatt gatagcttta ctgaatatga aaagacggaa
     3901 tatgaacatg ttatcagtaa agaaattcat cctgttgacg gggcgttgaa tatgggtgaa
     3961 gtggtgcgtg cggtaagtga ggcttcgaac aacgaggctg tattggtgac agatgtagga
     4021 cagaaccaaa tgatggctgc tcgttatttt aaatacagta agaaccgtag cattgtaact
     4081 tcgggtggat tgggaacgat gggattcggt cttcccgctg ctataggcgc tactttcggt
     4141 cgcccggatc gtactgtatg cgtatttatg ggggatggcg gtttgcagat gaatattcaa
     4201 gaattgggaa ctatcatgga gcaaaaagca ccggtaaaga ttattttatt gaacaataac
     4261 tatttgggta atgttcgtca atggcaagct atgttttttg gtcatcgtta ttcatttact
     4321 ccgatgttga atccggatta tatgaagatt gccgaggcat atgagattcc tgcccgccgt
     4381 gttatgaagc gtgaggaatt gcaggctgct atccatgaaa tgttgactac tgacgggcca
     4441 ttcctgctgg aagcttgtgt gatagaagag ggaaatgtgt tgccgatgac acctccggga
     4501 ggctcggtga atcagatgtt actggaatgc taatttaata attatggaca agacattata
     4561 tacattaatc gttcattcag aaaatatcgc cggtttgctg aaccagatta cggcagtgtt
     4621 tactcgccgc caaattaata tcgaaagtct taatgtttct gcatcttcca tcaagggggt
     4681 gcataaatat actattactg cttggaccac ccaggatgtg atagaaaaag tggtgaagca
     4741 gattgaaaag aaaatagatg ttttgcaggc acattatttt actgatagtg agatttatca
     4801 gcatgagatt gctttgtaca aggtttctac tcctgaattt caggagaatc ctatggcatc
     4861 taaagttatc cgccgttata gtgcccgcat tgtagaagtg aatccggttt tctctattgt
     4921 tgaaaagaat gggatgagtg aggaaattac tgctctttat gaggagttgc gcggattggg
     4981 atgtgtgttg cagtttgtcc gttcgggacg tgtggccatt actaccagct gtttcgagcg
     5041 tgtgaacgaa tatctgaccc aacgcgagga aaagtatcgc cagcaaaaaa cagaataatg
     5101 atgagtgaga ataaagtagg aacatacaga tttgtggcag aaccctttca ctgtgatttc
     5161 agtggaaagt tgaccatgag tgtgttgggt aatcatttac tgaattgtgc cggctttcat
     5221 gctgccgacc ggggtttcgg aattgctacg ctcaatgaga atcattatac atgggtactt
     5281 tcccgtttag ctgtagagtt agagaatatg ccctgtcaat atgagggttt cagtattcag
     5341 acatgggtag agaatgttta tcgtcttttt acagaccgta attttgcaat tttggacaag
     5401 gaaggaaaga ctgtcggata cgcccgttct gtatgggcga tgatcagtat ggaaactcgc
     5461 aaacctgctg acctgcttac gcttcacgga ggtagtatca ttgattatgt atgcgataag
     5521 aaatgtccta taagcaagcc cggtcgtatt aaggtgacag agaaagctcc ggtttctgaa
     5581 taccagacca gatatagcga tattgatatt aatggtcatg tgaacagtat taagtatata
     5641 gaacatattc tcgatttgtt tcctatagag ttttttaaag agaaacggat taaacgtttt
     5701 gagatggctt atgtagctga gagttattat ggtgatatat tgagtttcta ccgcgaggaa
     5761 gtggaggaga aagaatatga tatagaggtg aagaagaatg gcacagatgt tgtcgttcgt
     5821 agtaaggtga tatttattta gaatctaatt tttaattttt aatttataat ttaaaatggc
     5881 acaattgaat tttggcggcg ttacagaaac tgtagttatc cgcgatgaat ttcctttgga
     5941 aaaagcacgt gaagtattga aagatgaaac aatcgctgtg atcgggtatg gtgtacaggg
     6001 accgggacag tctttgaatc tccgggacaa tggtttcaat gtaattgttg gtcagcgtcc
     6061 gggaaaaaca tatgaaaaag cagttgctga cggatgggtt ccgggtgaaa ctctgtttgg
     6121 tattgaagag gcttgtcaga aagcgactat cgtaatgtgt ctgttatctg atgcagctgt
     6181 tatgtctgta tggccgacta tcaaacctta cttgacccaa ggcaaggcac tttatttctc
     6241 tcatggcttt gccattactt ggagtgaccg tacaggggta gttcctccta ctgatattga
     6301 tgtgatcatg gtagctccta aaggttcggg tacttcactg cgtaccatgt tcttggaagg
     6361 tcgtggcttg aactcttcat acgctatcta tcaggatgta accggtaagg cttatgaacg
     6421 tactattgca ttgggtattg gtatcggttc aggctattta ttcgaaacga ctttccagcg
     6481 tgaagcaact tctgacctga caggtgaacg cggttcttta atgggggcta tccaaggatt
     6541 gttgttggct cagtatgaag tattgcgtga aaacggacat agtccttctg aagcatttaa
     6601 tgaaactgta gaagaattaa cccagtcatt gatgcctttg tttgctaaga atggtatgga
     6661 ctggatgtat gctaactgct ctaccactgc tcagcgcggt gcattggatt ggatgacccc
     6721 atttcacgat gctatcaaac ccgtagttga aaagttatat cacagtgtga agactggcaa
     6781 cgaggctcag atttctatcg attctaactc taaacccgat tatcgtgaaa aattggaaga
     6841 agaattgaag gcattgcgtg aaagcgaaat gtggcagact gctgtaaccg tacgtaaact
     6901 tcgtcctgaa aataattaat agttagtatt taatgtagaa agcggggatg cgatgaggta
     6961 tctccgcttt cttttatata tattaatgtt agtggtgttg tttatatcat gtgtagtcgc
     7021 taattttgtg aaaacttgac ttaggcatga ataatagatt atcactttta ttaatagggt
     7081 gcatatttcc ctttctatct ttttatgcac aaaagaacat gaatctcccg ccatattatc
     7141 ctacagtaaa aggtattacg gattatgctg tgtggcagct cgtatatccg gattctttat
     7201 taagggccaa tattgcaggt gaagctgtgt gtacgctccg cattgatagt ttggggactg
     7261 tccgttgtaa atatattgaa gccactcacc ccttgtttgc taaggcggcc gaagatgtga
     7321 ttgagggtat gcgtgaatgg cagcctgcaa agaaagcggg tagagatata gatactacta
     7381 tcgtctttca tattcctttt aatcctgatg tttacagtga ccgcatttgg cggcagcagc
     7441 aagttctgga atcttgcaga ggacaacttg tcgattccat gcctgtcttt cctgatgata
     7501 ttcgtagtct tgttatggga aatatgagtt ggcctgacga taaagtggat aaagccgtcg
     7561 ctatttgccg ttttacggta aatgaaaaag gagaaattgt ggatatccgt gtgataaaag
     7621 gtactcatcc ggcttttgat aaagagtcca tacgtattct ttctaatttt ccccggttga
     7681 ttcctgctat gaaaaacaga aaatctgtgc catatgatta ttttttaact atgcgttttt
     7741 ggaaagagga tctggagcat tatttattat atagggaatg cgcacaggaa gatttggaaa
     7801 agatcacttg ggagccttat agatactctt cttatcccgg tggtactgtt gctttgacgc
     7861 aatttattaa ttctcatctg aaaattactc ccgaaatgaa ggctacggga aagcagggac
     7921 gggtgattta tagtttcaat gtggatatag atggttcaat gaaagatttt cagttggtga
     7981 gaggacttga tccattaatg gatgccgaag cattgcgggt acttcaatta gtgaatgaaa
     8041 gatggagtac ggggtattat ttcaattcaa agaaatggta tcgggagttt tatgtgaatc
     8101 aattcaccat tccaattatt tttagttggt agtggtggca gagggcagat acgcggactg
     8161 ccctctgcga aaatgatagc attattaaaa gtggatgaaa tttattaggt aggattcatg
     8221 ctgtttcata atagcgggat gattgtgata taaatacctg taataattgc tgaagtaata
     8281 actcccgata tattggctcc tagtgcatct cctaggataa atgaatcagg attgtcttta
     8341 ctgacaatct tttgtgccac tttggcagta gttggtacgc agcttacagc agcaatgcca
     8401 atgactggat tataatttcc tttcttgata tagtacatga tatatccgcc taaaatacct
     8461 ccgatacctg atagtaacaa tgccaacata cctagtatca gcaattttaa gattttagga
     8521 tctagtagca gatgagcgtc gcaaagcact cctaataata atcccagcat aaaagtagaa
     8581 ccgtaaagca atggaccgct gacaaaatca taaatatgtt tcatccctga ttcacgtaca
     8641 gccactccta gaaatagaga gaaaaacagg ggagaggcca ctggaaaaag gaagcagagt
     8701 acagcgcaga gtaccgctgc gaaagcaagc tttaccttgg catcgtaatt cttcggcgct
     8761 ttctttacgg tcattttgat ggaacggaaa cgtttgggaa tcagtaattt aaccaaatag
     8821 ggataaccgc cgtaagtcaa tcctaaatag agataagcta ccacggtaat cggtacaaac
     8881 aaatgcttgg ctaatgccaa tgaagtgaac agtaccatcg gaccatctgc acctcctacc
     8941 atggctacag aagcactctc ttgtgccgat aagccaagtg cattggcaat tggcaatgtg
     9001 agaaaggttc ctagttctcc gcaaagtgcc agaaacaaac tagcaaaagg tttttgtagc
     9061 aggaaaccta catctagcaa ggttccgatt cccatgaaga cgaaacaagc gatgagtcca
     9121 ttactgaatg tgagggtgta aaccggttgc agaaaatcta tttgcatggt attcatcaat
     9181 tcgtctgtat ccgagagcat gggatcaaga aaaagattgc ctagatttcc atccggcatg
     9241 attaatgttc cacaattgat ggctatcata ccgagtccca ttggaatcat gactatgggc
     9301 tccaatattc ctttccaacc tagataaatg agtagaaatc ccaaaagaat taaaaaaacg
     9361 cgcgcacagg caaggaacca accgctttct atcattgtac caatgccttg gaaaagtatt
     9421 ccaaaatcta tattttccat atctaattgt tgattttcag gttatttatt cattgaaaga
     9481 ttctttttca catgagtgct tttttgttgc tgattatgca tttcctcccg tttcttaagg
     9541 tagatcatct ttgtgtccgg atagtaataa tctatcagat ttaattggga tgctccatga
     9601 ctgacaccat ggtagtaacc accttcctgt tttcctctca gatcgctgtt cattcctcgg
     9661 ttccagtttt cacggctgtc tcctagagct tccatctctt ctggagaatt attccatact
     9721 aattggataa aacgggcacg tgcttttttg atttttctta aacgttgaag ttccaatagg
     9781 tgggagctat agaaatccat agaatctgct gccagcgcta ttcctttaat aatagcagcg
     9841 acaaaaaaac cgatgaggaa agtaagcccc atcatggcca atgtggataa aaataagtgt
     9901 agcattataa tataaatgtg atttagtagg taaaatagta ttaaattccg agttatagtg
     9961 atattcacat cgt
//
