LOCUS       gnlProkkaKCOEMNOA_112  12745 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KCOEMNOA_112.
ACCESSION   gnlProkkaKCOEMNOA_112
VERSION     gnlProkkaKCOEMNOA_112
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-18 09:53:40
            Original ID  :: gnl|Prokka|KCOEMNOA_112
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12745
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12745
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[7433:8164]"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      7434..8164
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     cand_cluster    1..12745
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12745
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="1"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     CDS             complement(61..1362)
                     /locus_tag="ctg112_1"
                     /transl_table=11
                     /translation="MEHILLLFFSFLIEAIIMWQYSSSLFLSAHSAKVKISFICFLYGI
                     LFLFSFMEKVWLNIIVYFLINFLFLYIQFKIDLLIAIFHSAILTTIMGLSELFMFSFMS
                     QFAPHFLENTKGGLIIYTLSSKILFLTIIYLLMHFFKKTDPKQENYIDYTDFILMLIPV
                     SCLFIIITFFNIGEHFVFIAPINIMVTLSTVLILFINLLVFGMNQYNHRRNIEFTDMQL
                     LLQKEADSAEYYKMLLSQTENRNILIHDIKKHLQTIKLLNEKKDTSKINAYICQLLDSS
                     DLQEPTRICDNEILNAILGRYQRQCSIKSISFHADIRSNILKQFSPYDLTSLFCNLMDN
                     AFEAVEKIPEAFIEVTAQKKENSPFIVIVVINSCRTAPAYDSDHLPISNKENTTKHGYG
                     IKSIKKVTKKHGGNLQMYYDDSSSTFHTIITLKS"
     CDS             complement(1370..2077)
                     /locus_tag="ctg112_2"
                     /transl_table=11
                     /translation="MRILICDDDTLILEHIYKLLKYYFESAHLKMPEIISYSNGESLLM
                     DKGSKDIVFLDIEMPGMNGIYVGNELKSQNRNVIIFVVTSYSEYLDEAMRFHVFRYLSK
                     PLNKQRFLRNLKDALTYYNTMTQIIPIETHDGIYTVPSSYIIAIEAQGRKIIVHTIQKD
                     YISVHNMNYWAEHLPENSFFQSHRSFIVNFEHITDFDHTTIHMFSNSFTAYLTRRKYTA
                     FKNAYLLYLESTR"
     CDS             complement(2044..2367)
                     /locus_tag="ctg112_3"
                     /transl_table=11
                     /translation="MNRHFKSLFGLFSFLETDQGSVAYYKFTYIILTGIQKRTVEYSHC
                     SFFSLIVFSRSYLSSEYTTKNAIILSFHVHPLQVLYVYDMINIFKRKSGDIECGFLFVM
                     MTH"
     CDS             2497..2880
                     /locus_tag="ctg112_4"
                     /transl_table=11
                     /translation="MMNKKIKRIFCGLTASLCMVGSTVPAMAQTVSFDITVPGDILSQR
                     AKKADYEQRFYVTGNSFNKIGTLHCTSINRKFSSIKSNVASINPNKLSDKAFYLTDAPA
                     EQYYYMTTSASVSNLHVTGRYTP"
     CDS             2961..4055
                     /locus_tag="ctg112_5"
                     /transl_table=11
                     /translation="MIKKLLLYLILGVITIGSGCGKNVTSEKSNIVNRQENDKAEVEKA
                     FPRTCNIESKSGKVKFNCTLELPESLNGRTIQKTSVEGVHNYNRDKAYSLFAGGKEISE
                     KHQYGDDNNGFDCYRFSDGTSLEVGSTFRWSSATSSFYSYLGVQQSDYIDLFSGGAVSL
                     DKDNCISEVKNDINELGYDAENFSFQAFPLSVDGMRKLRNEELNDGLLEEGQTNEPTSD
                     DEAYFIYAYQENTGIPVFHELMSVAEQLSDDSPDNAPVQAIYSARGLEELSIDYIYDFK
                     NEQNTVTLKPFEEIASVVEEKYENILNDAKYEITRAKLYERVYTDENQKYAEEPVWYFE
                     VNDGSRKTVMLVNAETGKEINLPS"
     CDS             4065..4283
                     /locus_tag="ctg112_6"
                     /transl_table=11
                     /translation="MSSSTIPYCAVEERRRLNQCMEKTSNDYEKEIYRKIRDMPVPYEK
                     LNEILENSRDIIISLEPLSIKRLSPFE"
     CDS             4792..4956
                     /locus_tag="ctg112_7"
                     /transl_table=11
                     /translation="MEIDFIQELKKRDELLDGYLRQIEIQEEFIQKQKELIEYLEDHIS
                     KITDIVSSV"
     CDS             4981..6654
                     /locus_tag="ctg112_8"
                     /transl_table=11
                     /translation="MPDTYDHITLMCRLKAAQRRNKELESGERYIQLEELYQKEYNVYE
                     HKIEKLKKELADAHKETIRVRNYWFQILEDMLREFEKAQKRSAQELRKMEIRALNAEKQ
                     RDDALDKAAVFRHQFYEAASRLEEEQGKNLKLRAQINRDYENSSIPSSKAVRRKKITNN
                     WEKTGRRPGGQPGHKGHCRKRQEPTQPVILLLPPEEVLEDCAFKKTARTIVKQMVSIRM
                     VLNVTEYHADVYYNSHTGERAHAAFPDGVIDDVNYDGSIRAFLFLLNNDCCTSIDKSRV
                     FLSDLTGGKLNISKGMISRLNREFALKTEPERRSAYADMLLSPVMHTDCTNARENGKSC
                     QVYVCATPGGKALYFAREKKGHEGVKGTVTEDYQGILVHDHDITFYNYGADHQECLAHI
                     LRYLKVSIENEPDRTWNKKMHALVQEMVHFRNGCRQPHGPDPEIVSGFEKRYREILETA
                     RKEYENIPANDYYKDGYNLFLRMEKYMHNHLLFLHDIRVPATNNEAERLLRNYKRKQAQ
                     AVTFRSFESIDYLCQCMSMLVLMRLEDPANIYDRVSRIFG"
     CDS             complement(6803..7120)
                     /locus_tag="ctg112_9"
                     /transl_table=11
                     /translation="MRRKELHIKQAELAETLEISNNHMSSIENGRQKPSLDTFIRLCDC
                     LNVTPDYLLLGSMHAYNLPQDILDKLRLCSQEDIILARDFIELLVKRNRKKHITDSPIS
                     F"
     CDS             7434..7583
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: TIGR04223"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg112_10"
                     /sec_met_domain="TIGR04223 (E-value: 1.5e-12, bitscore:
                     37.6, seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQKNVKTTVAKGMKTVLDTVLKTEANTTSCAIMFQPKAPEELMKY
                     RRSK"
     CDS             7583..8164
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg112_11"
                     /sec_met_domain="AgrB (E-value: 4.8e-35, bitscore: 110.7,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNICTDKVTDWMIRCKVINESEKELYQYALYSAILQIIPLLLAAG
                     IGFCFGSMRCGIIMILPFMILRKYSGGFHAKRLEFCLLGSSLLLLLCIFLCMRLVYRDA
                     LFFITVVLAISLIQFSPIENNKRKLDLLEKKRYKKIIVISVTVFLITALILLWLNKDRY
                     AICIFIGIQLTASLQIPCLFLKMKKDQKEP"
     CDS             8307..8690
                     /locus_tag="ctg112_12"
                     /transl_table=11
                     /translation="MMNKKIKRILCGLTASLCMVGSTVPAMAQTVSFDITVPGDILSQR
                     AVKADSEQRFYVTGSSFNKSGTLRCTSINRNNNTIRSYTASIRPDKLSGNASYQKTAPS
                     GQYYYMTTSASVSNLHVTGRYTP"
     CDS             8789..9883
                     /locus_tag="ctg112_13"
                     /transl_table=11
                     /translation="MVKKVLLCLILGTVIISSGCEKNATSEENSAETVQNDANSKTENS
                     FPKTYNAESKSGKVKFSCTLEIPENLNGRTIQKTSVAGLRDYNKDKVYAMFAEGKEISK
                     KDQYDWDGGDVANYTFSDGSSLYLDNYVHWGSTTSSLYSYLGVQQADYIDLFSSGSVSL
                     DKDNCISEIKKDMNEFGYDTEDLSFQAFSLSVDAMKKLRDQELNNGLLEEGKTKEPTSD
                     DEAYFIYAYQKNNGIPVFHELMSAAKQMSDDSPDNAPVQAIYSARGLEELNIDYIYDFK
                     NEQDMVTLKPFEEIASVVEEKYENLLNDSKYEITRAKLCERVYTGEDQKYAEEPIWYFE
                     VVENGNNKTVTLVNAETGKEINLP"
     CDS             9896..10183
                     /locus_tag="ctg112_14"
                     /transl_table=11
                     /translation="MSSSTIPYCAVEERRRLNRCMEKASDDYEKEIYRKIRDMPVPYEK
                     LDEILKDSRDIIISRQHRKNRIRNFLVCVGVFGFMFVVLAMYIIMEKQRG"
     CDS             10188..10949
                     /locus_tag="ctg112_15"
                     /transl_table=11
                     /translation="MEKTKYLRTDFSRLFKKYPLYLAIVGVAVSFIFSLENYAFEKGMV
                     NVNVMDTYMFAVEMSGKMIAYAFCASAFATVFCEDLENKYLRYSIGRGNLIKYVFSKTI
                     VIYVSSIITMVLGTFLFVIYLRLQLPWTPYLEKPDMSGMYETLWGNGHFMAYIFVVALQ
                     MGMLAGTLSLAASFVSIFITNKMLIMLTPILLYQILMEFRGSGWANIMIFDPALFQFKS
                     DIEYFLIVCGFSLVPSIFFVLGIYRVIKNRL"
     CDS             10961..11821
                     /locus_tag="ctg112_16"
                     /transl_table=11
                     /translation="MRLLKYIWKNTVLKCFNSKMAVFIILMLVTSRSYLNPLREFSVAV
                     NYPVSWCVFPFVMCSFTYLIIFWFGVIYVNSDVPFMQHVNMYHAIRSGRRQWGLGQIGG
                     IFLRSLIMVLITIFCTILPLLSKIEWSNEWGKLLRTAATTNALSRYQSSVVIYYDIFSE
                     YTPLELILLEILICTLTCTFVGVLMFFLSLYINKIIAVAGGLALAISLFPVLNMHPLIR
                     YKLARFVPTVWAELARIATVDHTYYWLPSLTYMVLFLLVGIAIMTSFIIYKIRHVEFNW
                     ENEDM"
     CDS             11836..12528
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 180.1; E-value:
                     9.3e-55)"
                     /gene_kind="transport"
                     /locus_tag="ctg112_17"
                     /transl_table=11
                     /translation="MDEKKYVIEVSHVNKNFKDNKVLKDVSLRCESGKIYGLVGHNGSG
                     KTVLFKIICGFLVSDEGTVTVNGKIMGKDKDMLTEAGIIIEDPGFLRNWSAYHNLEFLY
                     TIRNKKDKSYLYSILKKVGLNPKLKRPVGKFSLGMRQRLAIAQAIMEDPEILILDEPMN
                     GLDKNGVEEIRELLLKMKKNKLIILASHNREDIDVLCDEVYEMEDGVLRKNSNVKSVTD
                     KSYCLPEV"
ORIGIN
        1 tatttagaat gcttgtttat aggttatcgc tgaactacgt tttcaagaca gccccatttt
       61 ttatgatttt aaagtgataa tggtgtggaa cgtggaactg gagtcatcat aatacatttg
      121 aagattacct ccatgttttt ttgtgacttt ttttatactt tttataccat aaccgtgttt
      181 tgtggtattt tctttattgg atattggaag atgatcagaa tcatatgccg gagcagttcg
      241 gcatgaatta ataacaacaa taacaataaa aggagagttc tcttttttct gtgctgttac
      301 ttcgataaaa gcttctggta ttttttctac tgcttcaaaa gcgttatcca tgagattaca
      361 aaataaagaa gttagatcat aaggagaaaa ttgttttaaa atattacttc ggatatctgc
      421 atggaagctg atgcttttta tgctgcattg tcgttggtaa cggccaagga tagcgtttaa
      481 aatttcatta tcgcaaattc tggttggctc ctgcagatca gatgaatcaa gaagctgaca
      541 gatgtaagca tttatttttg aagtgtcctt tttttcattc aataatttga tagtttgcag
      601 gtgctttttg atgtcatgaa tcaggatatt ccgattttcc gtctgagaaa gaagcatttt
      661 ataatattct gcagaatcag cttctttttg aagcaaaagc tgcatatcag tgaattctat
      721 gtttcgacga tgattatatt gattcattcc aaataccaga agattaataa aaagaataag
      781 cactgtactc agcgttacca taatatttat tggtgctata aacacaaaat gttccccaat
      841 attaaaaaaa gttattatta taaacagaca ggaaacagga atcaacatca aaataaaatc
      901 tgtataatca atatagtttt cctgtttagg atctgttttt ttgaaaaaat gcataagcag
      961 ataaataatt gtaaggaata aaatcttgct ggacaatgta tatataatta aaccgccctt
     1021 cgtattttca agaaaatgtg gggcgaactg agacataaag ctaaacataa aaagctcaga
     1081 aagtcccatt atggttgtta aaatagcgga atgaaatatt gcaattaaca gatcaatttt
     1141 aaactgtata tataaaaaca gaaagtttat cagaaagtat acaataatgt taagccagac
     1201 tttttccatg aaagagaaaa ggaataaaat gccataaaga aagcatataa atgatatttt
     1261 tactttagcg gaatgagcag ataaaaacag gctggaagaa tactgccaca taatgattgc
     1321 ttcgattaga aaactaaaaa ataatagtaa gatatgttcc ataaaatctt tacctcgtac
     1381 tttcaagata tagaagataa gcatttttaa atgctgtata ttttcggcgt gtaaggtatg
     1441 cagtaaatga attgctgaac atatgtatag tagtgtgatc aaaatctgta atatgttcga
     1501 aattaacaat aaaacttcgg tgtgactgaa aaaaactgtt ttcaggtaga tgctctgccc
     1561 agtagttcat attgtgaaca gaaatataat ctttttggat tgtgtgtaca attatttttc
     1621 gcccttgggc ctcaatggca ataatatagg aagagggaac agtataaatt ccatcatgtg
     1681 tttctatggg aattatttgt gtcatcgtat tgtaataggt taatgcatct ttcaaatttc
     1741 tgagaaatcg ttgcttattc aatggctttg aaagataacg gaatacatga aaacgcatgg
     1801 cttcatccag atactcagaa tatgaggtaa caacaaaaat gattacattt ctgttttggg
     1861 attttaactc gtttccaaca taaattccat tcataccagg catttctata tcaagaaaaa
     1921 ctatatcttt agaacctttg tccattaaaa gactttcccc atttgagtag gatataattt
     1981 caggcatctt aagatgagca gattcaaaat aatattttaa taatttatat atatgttcca
     2041 gaattaatgt gtcatcatca caaataagaa tccgcattct atatcaccag actttctttt
     2101 aaatatattt atcatatcat atacatatag aacttgcaaa ggatgtacat gaaaagacaa
     2161 aatgatagca tttttggttg tatattcaga actaagatag cttcttgaaa aaacaataag
     2221 ggaaaaaaaa gaacagtggg aatattcgac tgttcttttt tgtatgcctg tcaaaatgat
     2281 ataagtgaat ttgtaatatg ccacagatcc ctggtctgtt tctaaaaatg agaaaagacc
     2341 aaaaagagac ttaaaatgtc gattcatgca aaatgggttg aaaattacaa aaaagtatag
     2401 ataataacac ttgtcattga ttttactgca aattacgcgc gtaaagaaac attacaaatg
     2461 tcctaaggat ttgtgaaaga aaagaggaaa cagattatga tgaataaaaa aatcaaaaga
     2521 atcttttgcg gattaactgc atctttatgc atggttggaa gtactgtacc agccatggca
     2581 cagactgtga gttttgatat taccgtaccg ggagatatct tatcccagag agctaaaaag
     2641 gctgattatg aacagagatt ttatgtaaca ggaaattcat ttaacaaaat aggaaccttg
     2701 cactgtacat caattaatag gaaatttagt tcgataaaat caaatgttgc ttctattaat
     2761 ccaaataaat tatcagataa ggctttttat cttacagatg ctccggcaga gcagtattat
     2821 tatatgacaa catctgcaag tgtttcaaat ctgcatgtaa caggacgata tactccgtga
     2881 tgttattttt tctataatgg atacccagag aagatactga ttattgtatc ttctctgggt
     2941 agtggtaagg gagaaaaatt atgattaaaa aactattatt atatttaata ttaggggtaa
     3001 taactatagg ttcgggatgt gggaaaaatg taacttcaga aaaaagcaat attgtaaata
     3061 gacaggaaaa tgataaagct gaagttgaga aagcttttcc gaggacgtgt aatatagaat
     3121 caaaatccgg gaaagtcaaa tttaattgta cattggaatt accagaaagt ctgaatggaa
     3181 gaactataca gaaaacttct gtagaaggtg tacataatta taatagggac aaggcatatt
     3241 ctttgtttgc aggaggaaaa gagatatctg agaaacacca atatggtgat gacaataatg
     3301 gttttgattg ttatagattt tctgatggaa caagccttga agtaggttca acttttcgtt
     3361 ggtccagtgc tacttcttct ttttattcat atcttggagt gcaacagtca gattatatag
     3421 acttgttttc gggtggagca gtttcccttg acaaagacaa ctgtatttca gaagtaaaaa
     3481 atgacataaa tgaacttgga tatgatgcag agaatttttc ttttcaggcg tttcccttaa
     3541 gtgttgacgg aatgagaaaa ttaagaaatg aggaattaaa tgatggtttg ctggaagaag
     3601 gacaaacgaa tgaacccaca tcagacgatg aagcgtactt tatctatgcc tatcaggaaa
     3661 ataccggaat tcctgtattt catgaattaa tgagcgttgc agagcaatta tcggatgatt
     3721 ctccagataa tgcacctgta caggccattt attctgcccg tggtctggaa gaattaagta
     3781 tagattatat ttatgacttt aaaaatgaac agaatacggt aacactgaaa ccttttgaag
     3841 aaattgcgtc agtagtagaa gagaaatatg aaaacatatt gaatgatgca aaatatgaaa
     3901 ttacacgggc taaattatat gaacgtgttt atacagatga gaatcagaaa tatgcagaag
     3961 aaccagtctg gtattttgag gtaaatgatg gcagtagaaa aacagtaatg ttagtcaatg
     4021 cggaaaccgg taaagaaatt aatttaccat cataggagat tgatatgagc agttctacaa
     4081 ttccatattg tgcagtagaa gaaagaagaa gattaaacca gtgtatggaa aaaacatcga
     4141 atgattatga aaaggaaata tacagaaaaa ttcgcgatat gccggttccg tatgaaaaac
     4201 taaatgaaat attagagaat agcagagata ttatcatatc tttagaaccc ttgtccatta
     4261 aaagactttc cccatttgag taggatataa tttcaggcat cttaagatga gcagattcaa
     4321 aataatattt taataattta tatatatgtt ccagaattaa tgtgtcatca tcacaaataa
     4381 gaatccgcat tctatatcat cagacgttct tttaaatata ttcatcatat catatacata
     4441 tagaacctgc aaaggatgta catgaaaaga taaaatagat gaatttttgg ttgttactgt
     4501 tcaaaggtat gtataagtca ttgtaaaaag tgacgaaatt attttctcta ttttgtggat
     4561 aattatcttc agcagaaaaa actgtattta tagttttttc tgctgttctt tttcacaaaa
     4621 gttatacacc gaatcctatc cattctttca gacagaggcc ttatatctac tcatttccaa
     4681 tcttataatg gagatttatc cacagtcaga ttgcccaatg ggtcatttcc ggaaattcgc
     4741 ttttttcctg catttctgct atactttttt caagaaagag aggttgtttt tatggagatt
     4801 gattttatac aggaactaaa aaaacgtgat gaacttcttg acggctatct caggcagatc
     4861 gagatccagg aggaattcat ccagaaacag aaagagctga tcgaatatct cgaggatcat
     4921 atctcaaaga tcacagatat cgtcagcagt gtttagcagg actgtaccgg aggaaaacgt
     4981 atgcctgata cttatgatca tatcactctc atgtgtcggc tgaaagctgc acaacgcaga
     5041 aacaaagaac tggaatctgg tgaaagatat atccagttag aagaacttta tcagaaagag
     5101 tacaacgttt atgaacataa gattgagaag ctgaaaaaag aacttgcaga tgcgcacaaa
     5161 gaaacgatcc gtgtgcgcaa ttactggttt cagatactgg aggatatgct ccgggagttt
     5221 gaaaaggcac aaaaaaggtc cgcgcaggaa ctccgaaaaa tggagatccg tgcactgaat
     5281 gcagaaaagc aaagagatga tgcactggat aaagcagccg ttttcagaca tcagttttat
     5341 gaagcggcat ccagactgga agaagaacag ggaaagaatc tgaaactacg ggcacagatc
     5401 aaccgcgatt atgaaaactc ttctattcct tcttcaaaag cagtacgacg caaaaagatc
     5461 acaaacaact gggaaaaaac aggcagaaga ccaggcgggc agcccggcca caaagggcac
     5521 tgccggaaaa gacaggagcc tacacagcca gttattcttc ttctgccacc tgaagaagtg
     5581 ctcgaagact gtgcttttaa aaagactgcc aggaccatcg taaagcagat ggtaagtatc
     5641 cgtatggtcc tgaatgtaac ggaatatcat gcagatgttt attataacag tcatacggga
     5701 gaacgtgcac atgcagcatt tccagacgga gttatcgatg atgtgaatta tgatggcagc
     5761 atacgggcat ttctgttcct tctgaacaat gactgctgta catccattga taagagcagg
     5821 gtatttctgt ccgacctgac gggtggaaaa ctgaatattt ccaaaggcat gataagcaga
     5881 ctaaaccggg agtttgcttt aaaaactgag cctgaacgca ggtctgccta tgcagatatg
     5941 ctgctttccc ctgttatgca tacggattgt acaaatgcca gggaaaacgg aaagagctgc
     6001 caggtatatg tctgtgcaac accgggcgga aaagccctgt actttgcccg cgagaaaaag
     6061 ggacacgaag gagtaaaggg tacggttaca gaagactatc aggggatcct tgtccatgac
     6121 catgatatta ccttttataa ttatggagca gatcatcagg aatgccttgc ccatatactg
     6181 cggtatctga aagtcagcat agagaacgaa ccagaccgta cctggaataa aaaaatgcat
     6241 gcactggtgc aggaaatggt ccacttccga aatggatgcc ggcagccaca cggaccagat
     6301 ccggaaatag tctccggatt cgaaaaacga taccgtgaga tactggaaac tgcccggaaa
     6361 gaatatgaaa acattccggc aaatgattat tataaagacg ggtacaattt attcctgaga
     6421 atggagaaat acatgcacaa ccatctgttg ttcctgcatg atatccgggt acctgccacg
     6481 aataatgaag ccgaaaggct tctaaggaat tataagcgga aacaggcgca ggccgtgaca
     6541 ttcagaagtt tcgaaagcat cgattatctc tgccaatgca tgagcatgct tgttttgatg
     6601 cgccttgaag atccggcaaa tatatatgac agagtgtcta gaatatttgg ataaagaaaa
     6661 ccgatggctt tgactgttat cagtctacac catcggtttt ctcaagtcca gctaaccctt
     6721 gaacagtaac ttttggttac ttatttagaa ataacaaaaa agaacagtga aaatattcta
     6781 ctgttcttaa tatgtatgtt tgttaaaagg atataggtga gtctgtaata tgcttttttc
     6841 tgtttctttt tacaaggagt tctataaagt ctctggcaag aatgatatcc tcttggctgc
     6901 acaggcgtag cttatcaaga atatcctgtg gtaaattata tgcgtgcata ctacctaaaa
     6961 gaagatagtc gggagtaaca tttaaacagt cacataaccg gatgaaagta tcaagacttg
     7021 gtttctgacg tccattttcg atggatgaca tatgattatt tgagatttca agtgtttcgg
     7081 ctagctccgc ctgctttata tgtaattctt tccgccgcat cttaatacgg ctccccatgt
     7141 catcataatg aaattcgatt tataacaccc tctttcatat gatgaatctt aacaatatac
     7201 ttttacaaaa tgaagaatgt tatacagaaa aattctgttg tacatttgat tttctgtatt
     7261 tcatagagaa aaattctgct atacatagta ttttaaactg gaaaagccaa taattatcca
     7321 tttttgaaga aaaataatct cttcattcca aacctatcga attataagac aaagagagtt
     7381 atgatataac ctgcaagaaa tcaatgacaa tttcgtgaaa ggagaacgag attatgcaga
     7441 aaaatgtaaa aactacagtg gccaaaggta tgaaaacagt attggatact gtgttaaaga
     7501 cagaagctaa tacaacatcc tgtgctatca tgtttcagcc aaaagcacct gaagaactga
     7561 tgaaatacag gagaagtaag taatgaatat atgcacagat aaagtaacgg actggatgat
     7621 acgatgcaaa gttattaatg aaagtgagaa ggaattatat cagtatgcat tgtatagtgc
     7681 tattttacag ataattccat tattgcttgc agctggaatt ggtttttgct ttgggagtat
     7741 gagatgtggg attataatga ttttgccatt tatgatattg agaaaatata gcggtggatt
     7801 tcatgccaaa cgattagagt tttgcctgtt ggggtcaagt ctgttactgc ttttgtgcat
     7861 atttctctgt atgaggttag tttacaggga tgcgttattt ttcattacgg ttgtgttagc
     7921 tataagcctg attcaattca gtccaataga aaataacaag cgtaagttgg atttgcttga
     7981 aaaaaaacgt tataaaaaaa taatagtgat aagtgttaca gtatttttga ttacagcact
     8041 aattttgctt tggttaaata aggatagata tgcaatatgt atttttattg gaatacagtt
     8101 aacagctagt ttacaaattc cctgtctgtt tctgaaaatg aaaaaagacc aaaaagagcc
     8161 ttaaaatgtc gcttcatgca aaatgggttg aaaattataa aaaagtatag ataataacac
     8221 ttgtcattga ttttactgca aattacgcgc gtaaagaaac attgtaaatg ctctaatgat
     8281 ttgcgaaaga aaagaggaaa cagattatga tgaataaaaa aatcaaaaga atcctttgcg
     8341 gattaacggc atctttatgt atggttggaa gtactgtacc agccatggca cagactgtga
     8401 gctttgatat taccgtaccg ggagatattt tatctcagag agctgttaaa gctgattccg
     8461 aacagagatt ttatgtgaca gggagttcat ttaacaaaag tggaacattg cgttgtacat
     8521 caattaaccg aaacaacaat acaataagat catacactgc aagtattaga ccagataaat
     8581 tatctggaaa tgcatcctac cagaaaacgg caccgtcagg tcagtattac tatatgacaa
     8641 catctgcaag cgtttctaat ctgcatgtaa caggacgcta tactccgtga tattgcattg
     8701 tttgtgacga aataatgacg aataattaat aacacaggga taggatgcaa gttatcctat
     8761 ccctgtgtgt ggataaagga gatcagctat ggtaaaaaaa gtgctgttat gtttaattct
     8821 ggggacggtt attataagtt caggatgcga aaaaaatgca acttcagaag aaaacagtgc
     8881 ggaaactgta cagaatgatg caaattcaaa aacagaaaat tcttttccca aaacatataa
     8941 cgcagaatcg aaatctggaa aagtaaaatt cagttgtaca ttggaaatac cagaaaattt
     9001 gaatggaaga actatacaga aaacttcagt agcaggctta cgagattata ataaagataa
     9061 ggtatatgct atgtttgctg aaggaaaaga aatatctaaa aaagatcaat acgattggga
     9121 tggtggtgat gttgccaatt atacattttc tgacggctca agtctttatt tagataacta
     9181 tgttcattgg ggaagtacta cgtcttctct ttactcatat cttggagttc agcaggcaga
     9241 ttatatagac ctgttttcga gtggatcagt ttctcttgat aaggacaact gcatttcaga
     9301 gataaaaaag gatatgaatg aatttgggta tgatacagaa gatctttctt ttcaggcatt
     9361 ttcattgagc gttgatgcga tgaaaaaact aagagatcag gaattaaata atggtttgct
     9421 ggaagaagga aaaacaaagg agccaacatc ggatgatgag gcgtacttca tctatgctta
     9481 tcagaaaaat aatggtattc ctgtatttca tgaattaatg agtgctgcaa agcagatgtc
     9541 agatgattct ccggataatg cacctgtgca ggctatttat tctgcccgtg gtctggaaga
     9601 attaaatata gattacatct atgactttaa aaatgaacag gatatggtaa cactgaaacc
     9661 ttttgaagaa attgcgtcag tggtagaaga gaaatatgaa aacttattaa atgattctaa
     9721 atacgagatc acacgtgcaa aattatgtga acgtgtttat acaggtgaag atcagaaata
     9781 tgcagaagaa ccaatctggt attttgaggt ggttgagaat ggtaataata aaacagtaac
     9841 gctggttaat gcagaaacag gcaaagaaat taacctgccg taaaggagat cagatatgag
     9901 cagttctaca attccatatt gtgcagtaga agaaagaagg agattaaacc gatgtatgga
     9961 aaaagcatcg gatgattatg aaaaagaaat ctatagaaaa attcgtgata tgcctgttcc
    10021 gtatgaaaaa ttagatgaaa ttttaaagga tagcagagat attatcatat ccagacaaca
    10081 tagaaaaaat agaattagaa attttcttgt ttgtgttggc gtatttggct ttatgtttgt
    10141 agtgctagcc atgtatatta ttatggaaaa gcaaagggga tgattgaatg gaaaagacaa
    10201 aatatcttag aacggatttt agccgtttat ttaagaaata tccgctgtat cttgcaatcg
    10261 ttggtgtggc agtctctttt attttttctc ttgaaaatta tgcttttgaa aaaggtatgg
    10321 taaacgtcaa tgttatggat acttatatgt ttgcagttga aatgtctggg aaaatgattg
    10381 cgtatgcatt ttgtgcttca gctttcgcaa ctgtattttg tgaagacctt gaaaacaaat
    10441 atttgcggta tagtattgga cgaggtaatt taataaaata tgtattttca aaaacgatag
    10501 taatttatgt atcttccata ataacaatgg ttttagggac atttttattt gttatatatt
    10561 tgcggctgca gcttccctgg acaccttatt tagaaaaacc agatatgtca ggaatgtatg
    10621 agaccctatg gggaaacggg cattttatgg catatatttt tgtagttgct ttacagatgg
    10681 gaatgttggc tggcacattg tctctggcag cttcatttgt ttctatattt atcactaata
    10741 aaatgttgat tatgttaact cccatcttac tatatcaaat tttaatggaa ttccgtggaa
    10801 gtggatgggc aaatataatg atatttgatc ctgcgttatt tcagtttaaa tcggatatag
    10861 aatatttttt gattgtatgt ggtttcagtt tagtaccatc aattttcttt gttttgggaa
    10921 tatacagagt aataaaaaat agattgtaga ggtgacaaac atgcggttat taaaatatat
    10981 atggaaaaat acagtattaa aatgttttaa tagtaaaatg gcggttttta taattttaat
    11041 gcttgtcaca agccgttcct atttaaatcc tttacgggaa ttctctgttg cagtaaatta
    11101 tcctgtatcc tggtgcgttt ttccgtttgt aatgtgtagt tttacatatt tgattatatt
    11161 ctggtttggt gtaatttatg tgaattctga tgtacctttt atgcagcatg tgaatatgta
    11221 tcatgcaatt cgaagtggta ggcgacaatg gggattaggt cagattgggg gtatattttt
    11281 acgttcgttg ataatggtat taataactat tttctgcaca atacttccat tgctgtccaa
    11341 aatagaatgg agcaatgaat ggggaaagct gttaaggact gcggcaacta caaatgctct
    11401 ttcacgatat cagagcagtg tggttattta ctatgatatt ttttcagaat atacaccact
    11461 tgagcttata ctgcttgaaa ttttaatttg tacactgact tgtacatttg ttggtgttct
    11521 gatgtttttt cttagtttat atataaataa gatcattgca gttgccggag ggcttgcact
    11581 ggcaatctcc ttgtttcctg tattgaatat gcatccgtta atccgctata aacttgcacg
    11641 ttttgttcct actgtatggg ctgagttagc aagaattgca acagtggatc atacttatta
    11701 ctggttaccg tctttgacat acatggtgtt gtttttgtta gtgggaatag caataatgac
    11761 aagctttatt atatataaga tcagacatgt ggagtttaac tgggaaaatg aagatatgta
    11821 ggaggaacag gtattatgga tgaaaagaaa tatgtcatag aagtatcgca tgtaaataaa
    11881 aatttcaagg ataataaagt attaaaagat gtttctctca gatgtgaaag tggaaaaata
    11941 tacggactgg tgggacataa cggatctgga aaaacagttt tatttaaaat aatatgtggt
    12001 tttcttgtat ccgatgaggg aactgttacg gtaaatggga aaataatggg aaaagacaaa
    12061 gatatgctta cagaagcggg aattattatt gaagatcctg gatttttaag aaactggagc
    12121 gcatatcata acctggaatt tctatataca ataagaaata aaaaagataa gtcatattta
    12181 tattcgatat taaaaaaagt tggtcttaat ccgaaattaa aacgaccggt aggaaagttt
    12241 tcactcggta tgagacaacg tctggcaatt gctcaagcaa tcatggaaga tccggaaatt
    12301 cttattttag acgagccgat gaatggactt gataaaaatg gtgtggaaga aatcagggaa
    12361 ctattgttaa aaatgaaaaa aaataaattg attattttgg caagtcataa cagagaagat
    12421 atagatgttc tctgcgacga ggtatatgaa atggaagacg gggtactacg gaaaaattca
    12481 aatgtgaaat cagtaactga taaaagttac tgtttaccgg aggtataaat taacggatta
    12541 catatcagtg tagtgtatat attagttttt agagatcgtt ttcaggacag ctcctcttga
    12601 ctactactca tattttttga tctgaaaaac acatcttatt ttttcaaaat aatttgaata
    12661 attgcgcgtc gcattctcgt tactttagcc tgatgagtta gacgcgcaaa ttttttaccc
    12721 aaaggaaaac atatgtttat tttta
//
