LOCUS       gnlProkkaKCOEMNOA_52   11443 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KCOEMNOA_52.
ACCESSION   gnlProkkaKCOEMNOA_52
VERSION     gnlProkkaKCOEMNOA_52
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-18 09:53:40
            Original ID  :: gnl|Prokka|KCOEMNOA_52
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11443
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11443
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[1179:1443]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1180..1443
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..11443
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..11443
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             383..1108
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Metallophos_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg52_1"
                     /sec_met_domain="Metallophos_2 (E-value: 1.1e-09, bitscore:
                     28.9, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISDLHEHEFGKDNVKLVEKIREQNPDIILMVGDFVNQDSTESTV
                     AVKLVEQLSKLAPVCYSLGNHEESYMAKTDWNFPAEIEKAGAHFLDKEYVDVDIRGTKL
                     RIGGMFSYAFGADGKDSAAAAPEDVKNFLMDFQDTDRLKIMMAHRPDSFIFGDAASVWD
                     VDLVVSGHDHGGQVVVPFAGGVFGGDQGYFPKYVHGMYEKERLHLFVSSGLGSANEPLP
                     RVNNLPEVAVVEIEKSTQT"
     CDS             1180..1443
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg52_2"
                     /sec_met_domain="PF05402 (E-value: 2.3e-21, bitscore: 66.2,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PqqD_RRE (E-value: 1.1e-09, bitscore:
                     28.3, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 5.2e-18,
                     bitscore: 55.2, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVDDGFVLREIAGDYVIIPTGKTVLDFNGMITVNEVGVSIWKML
                     QEETTFENIVQGILDEYDADEETVKADVQEFLDRIKEAGILK"
     CDS             2271..6287
                     /locus_tag="ctg52_3"
                     /transl_table=11
                     /translation="MTGEKNAPYAKLNQWLSNLPGYALNGVDSTDNVNAPVPLYFGDLL
                     HTSQAGGNGNLSWYWKGANVAFGPNKETASKDVAQGIVGKNLDDGNLITSYTNENGDPV
                     KVPFFNEDAYPNQSKYMRFYNNLQFPFTKTTNDKGVSTYSFDSAKNTVYYDYDNKKIVR
                     KDDLKIHDASKDNSIGYFPFNSTDPDQSAKDNLNYGFGTQFTIPFTVTETGKNVDGSEM
                     EFNFTGDDDVWVYIDGALVLDMGGAHNKAEGKINFAKQEATIRTGTSNAKLGNSLTVGG
                     RTPAEPNGNTTVKFENIMVKKSGSEPVTLDKYMKKSGTVHELKMYYMERGMWNSNMSIS
                     YSFVPLPSGLTLSKTLDTTDVNAGLKNAVQGLDNFDFKIQKKNLKTDEANYSDVENLGY
                     TLYDYDDRTFPGQEAKDSTATFSSSYFASDFINTKDKNNSSAFYAGTGFQITESIPQGT
                     KLQYDTSKTRWGVYDSITSRAAIEGGKGAVATFNMGDDTSSEMDVVNRYVNFVNTPKVG
                     SLSVAKKYEGYAPENETFGFTVLVDLTGHDYYDSYKLKYTGTQNGTTDENGHFTLKVGD
                     TVTFAGIPAGATYKVVEDSPQAGDTWVQETTSDVTGKIEADVTSAAVVTNKTKTTVKDY
                     VIYAEAGKTVTYAPDGVTITELTAQTTGDTVINTNVKGGKGEFTPESPNEKYVVNYTGT
                     TTNNGNFTGTITVYTYKATDKVYVFDYGLESNIADATTGDGLFQDGTFYNDKAKDTVDD
                     TTAKLDQITSEASDIDDRQTEITGNQNAINRDGSAEGEVTFKPIAFMDKVEKYTYTANI
                     TKVDTEFNSANPETGTTVHGTIKTMPANVVYYEDNFNEKANSSNSAVKIIYSENNTSKD
                     GTDVKLEQSNDQSEQYGHDNAYANGDKYSSGSSTKMEKSATATFTFKGTGFDIISRTNT
                     ETGTIGVKVYKGEKASGEPIRNIPLITYYDDGDLYQVPVIHETDFDYGTYTVVVEVKSY
                     NPDGIVFYLDGVRIYEPLDDQKYTYEEGTTYDSDNYLESEVDAHIYEIRPMIIGNTVDG
                     KTANHAMLMQYTPGGNVVLSAGGNTVVETLNGIVPEGATETTDDFERYWKWGPNNELYL
                     EPGNAVGFLIPADIYDSTKPYATFQIGAKATSNKAVTLKTILPDGTEAKDSTITVNSAT
                     DMYYKINVTDEMKTKDGKYYQVVIANTDGGMVSLTNIKSTCDPIDFGVPAADTTAMRMM
                     AASMISAFSTKDEVVSEAAFATVVRSGRDATLAVTSTVGVEKLKITDSNGQVMDNSTLN
                     ISYTDKVLNGNKLRTWRVKFKPNLKRGKYKYTVEGITAENKATVRIGTPTLTVR"
     CDS             6303..6593
                     /locus_tag="ctg52_4"
                     /transl_table=11
                     /translation="MKKKYSKPCIAVENFVLQEFIAGSCSVKMNYANDTCVTEDKLTTG
                     GIDDKLAAQIKGIIHEYQYFQSTSTCSNEYKGTDATDGVCYFTATNAIFAS"
     CDS             6752..7627
                     /locus_tag="ctg52_5"
                     /transl_table=11
                     /translation="MNEITIQIANINFCIECKDEFEIVDYFKIFQNTNKEKNACNVHYQ
                     VKKIEQSIFLENEPVYQNERMTVYRIGSVEYRQFPWWNDEANYPMTLKHDINQPDEYEF
                     LLTAPQMEMFKNKLHFGTYLALERVMLDYDCFQLHASVIRVNGHGILFSAPSGTGKSTQ
                     ADLWEKYENAEIINGDRGMIRKQEDGTFQVYGSPFAGSSQIMTTMSAPVKAVVVLSQAP
                     HNKVCRLGVLKAFTKIYRETTINAWDTEFVMKMTELLNQFVKRIPVYHLECRPDQDAVE
                     VLKKEIFCDN"
     CDS             7712..8581
                     /locus_tag="ctg52_6"
                     /transl_table=11
                     /translation="MVKLQNSENKKKTKKVVLLVGVIIIVIIGILLALKLTKNDSKEKS
                     ATEADAYEIVKPGKDTLDVSKIQGYSAKVGVEDKKEEDTKEKDDSDKKDDSKETEKAEQ
                     IVLSDSNLTVESIGAYSGSFIEDGSDEATKNVTAMLITNNSDQMLQVALIDFQVNSNET
                     ASFKVTNLPAGTSTLVLESNKREFSDKDTYTYGNAATGYMDQPTLEEDKVELKTENGKI
                     TLKNKTDKELKTVYVYYKYMQIGGAYLGGITYRTPFENVGAGKEAEAVAAHFNPDSSQI
                     MGVQILEN"
     CDS             8603..9751
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg52_7"
                     /sec_met_domain="PF04055 (E-value: 4.1e-22, bitscore: 69.6,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 3.5e-09, bitscore: 27.3,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKQQAPMQAQLRKYLYQKAAHNKVPLSGTFELTPRCNMNCRMCY
                     IRMSEAEMRARGREYTAEEWIEMGKACAKEGMLFLLLTGGEPFLRKDFRQIYTELKKLG
                     LLISINTNATLIDEETVEWLKKDPPMKVNVTLYGGGNETYKKLCGHPTGYDAATKAIDL
                     MHDAGIFVNINASFTKYNLDDMEDIFAFGKRREIQVNAATYMFPPVRSAKDGVTDDAVR
                     FTAEEAGRARAMADKYRLSKEEFEIRLKALHEGRDDFMGGEEECERTPDEKMGCMAGRS
                     SFWMTWDGRMTPCGMMNEPVARPFEIGFSDAWKSIYQATDEILLPSECKNCKKRFACMM
                     CGALTIAEGGGCSYKKPEYLCRQTEVFLEEMEKEYQKRETGV"
     CDS             9748..10977
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_5"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg52_8"
                     /sec_met_domain="NTP_transf_5 (E-value: 3.6e-47, bitscore:
                     151.2, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMTNTQKELLQALRCFMQGDEEYHLPERFSQLKELCDLAAMHKIL
                     AIIYEMIRRDSVLLLEENAPLAARWKKSAIAEVMLQVQRTAGFLELYQKLQKEGVHPLV
                     VKGLICRSFYEKPDFRISADEDLLLRKEEFETFDCILLEEGYKRQELDPKDLPYEIPYL
                     NPRNQVYIELHFSLFAEGEGAYGHLNQEFAGAFDRCICEQIEGVDIKTLSPTDHMFYLI
                     CHSFKHFLHSGFGIRQVCDMVMMAKHYTTRIDWREIQDKLAQLRMDTFFSALAKIGREY
                     LGCSWEKTGYVDYTQESVDCMPLLVDLLEGGVYGGSTMARRHSANMTLEAARRGKKATA
                     SSVWSSLFPGVSYMKGHYVWLCKYPWLLPAAWVMRLFGYAADRKHTEDQSSLEIGNKRV
                     ELLRKYHVID"
ORIGIN
        1 tgagctaata ttgtagtgaa atgtaaatta taggaagcaa tctttgggcg agaacgcgga
       61 ggttgcttcc tcttttgttg agataattgc aggtactggc agtaggacag ggcttcatcg
      121 cttacaaaat agggggatta tgtaaaagta aattggttat aacagatgca caactgcctt
      181 gattgtggta aaatattgaa ataaagtttc acgcaagaag gtgatcacca tgaaacaaca
      241 caagttttta aaaataacaa tttcactcat tctcctcgtt gcacttatca cggctgcgag
      301 catctttttg tcatacaatg ttttgacggt caggacattt tcgtatgaga cggacaaggc
      361 tgtggacccg gtgagggcgg tagtgatttc ggatctgcat gagcacgagt ttggaaagga
      421 taatgtgaag ctggtggaga agattcggga gcagaatccg gatattattc tgatggtggg
      481 ggattttgtg aatcaggatt cgacggagtc gacggttgcg gtgaagctgg tggagcagct
      541 tagtaagctg gcgccggtgt gctattcact tggcaatcat gaggagtctt atatggcgaa
      601 gacggactgg aattttccgg cagagattga gaaggcggga gcacattttc tggataagga
      661 gtatgtagat gtggatattc gcgggacgaa gctgcggatt ggggggatgt tttcctatgc
      721 atttggagcg gatggaaagg attcggcggc tgcggcaccg gaggatgtga agaattttct
      781 gatggatttt caggatacgg accgtttgaa gatcatgatg gcgcacagac cggattcatt
      841 tatatttgga gatgcggcgt cggtgtggga tgtggatctg gttgtgagcg gacatgacca
      901 cggtggacag gtagtcgtgc catttgcggg gggagtgttt ggcggagacc agggatattt
      961 tccaaagtat gtgcatggca tgtatgagaa ggagaggctg catctgttcg tgtcgagtgg
     1021 gcttggaagc gccaacgagc cgttgccgag ggtgaataat ctgccggagg tggctgtggt
     1081 ggagattgaa aaatcaactc aaacttgatg atgcgaagca gacatgctat attatatagg
     1141 aagaaagacg aaatatccta gaaagaatga ggagaaaaaa tgagagtaga cgatggattt
     1201 gtattaagag aaattgcagg agattatgtg attatcccaa ccggtaaaac ggtgcttgat
     1261 tttaacggaa tgataacggt caatgaggtg ggagtttcta tctggaagat gctgcaggag
     1321 gagacgacat ttgaaaatat agtgcagggc attttggatg agtacgatgc cgatgaggag
     1381 actgtgaagg cggatgtgca ggagtttttg gaccgcatta aagaggctgg gatattgaaa
     1441 tagaggtgta tgagaaaacg agtctcaatg tttatttttt aagatggctt aatatgtata
     1501 gtaggaaaat taccaaatca tatcaaattt tttagattat atataaaaaa atctacaaat
     1561 tatacaaaat ataacatttt cgggacgatt tacctattgt attttcatca aaaaaacttt
     1621 agaatatttt agaataaatc tattgctaaa actatgtttt cacgtagcag tagaaataac
     1681 ctattaatca tactcaattt aaagggaaga gagagtaaag tatgagaaaa agatttaaga
     1741 aacggttgct cggaatcatc cttaccatct tgatggtagt tagcgtgata cctgtgcagc
     1801 aagtacagcc cgtaaaagcg gcagcaggag atacgattcc agcgggaaca actatttatt
     1861 tacgccctaa tgctgcaaca acttggatta aagataatgc agttatggca tttaagacta
     1921 gtgcgaacaa taagcaatcg gaaattgttg ttatgagaaa gatggatgat ggtcttacat
     1981 ggtatggaac gacaactgca gctgcgacca atattgattt tcttcgctta aatcccaatg
     2041 acaccaatca ggtatggaat gaagcgggta catggccggg cttagaaagt ggaaaaaact
     2101 tatatacgtt tgcattacac acaggagtaa ctccaacagg aatgtggact acatattcaa
     2161 acacaggaag tgagactaca tcctatttta atgtaaatgc tacattagtt gattatttca
     2221 ataatggacg tgtggaacag ccaaaaaata cactttacaa tgagggtaat atgactggag
     2281 agaaaaacgc tccgtatgcg aaattgaacc aatggctttc aaatttaccg ggttacgcgt
     2341 tgaatggagt tgatagcacg gataatgtta atgcaccagt gcctctttac tttggtgatt
     2401 tattacatac atctcaggca ggtggaaatg gtaatcttag ctggtactgg aaaggcgcaa
     2461 atgttgcatt tggtccaaat aaagagacag ctagtaagga cgtagcgcag ggtatagtag
     2521 gaaagaattt agatgatgga aatctgatta cttcttacac gaacgaaaat ggtgacccgg
     2581 taaaggtacc tttctttaat gaagatgctt atcctaatca gagcaaatat atgcgatttt
     2641 ataacaattt acagttccca tttacaaaga caacaaatga taagggagta tctacatatt
     2701 cgtttgattc agcaaaaaat actgtttatt atgattacga taataagaaa attgtaagaa
     2761 aagatgattt aaagattcat gatgcaagta aagacaatag tataggatat tttccattca
     2821 atagtactga tcctgatcaa tcagcaaagg ataatttgaa ctatggattt ggtacacagt
     2881 ttacgattcc atttactgta acagaaactg gtaaaaatgt ggatggttca gaaatggaat
     2941 tcaactttac cggtgacgat gatgtatggg tatacattga tggtgcattg gtattggata
     3001 tgggtggtgc tcataataaa gctgaaggaa aaattaactt tgcaaaacag gaggctacca
     3061 ttagaacagg tacatctaat gcaaagctgg gtaatagcct tacagttggc ggaagaacac
     3121 cagctgaacc taatggaaat accacagtaa aattcgaaaa tattatggta aagaaatcag
     3181 gtagcgagcc cgttacgtta gataaatata tgaaaaagtc tggaacggta cacgaattaa
     3241 agatgtacta tatggaacgt ggtatgtgga actccaatat gtccatttca tacagtttcg
     3301 tcccgttgcc atcaggtctc actcttagta agacacttga cacaacagac gtaaatgcag
     3361 gattaaagaa tgcagtacag ggtcttgata actttgattt caagattcag aaaaagaatc
     3421 tgaagacaga tgaagcaaat tatagtgatg tagagaattt gggatataca ttgtacgatt
     3481 acgatgaccg tacatttcca ggacaagagg ctaaagatag tacggctaca tttagctcat
     3541 catattttgc aagtgacttt attaatacta aagataaaaa taacagtagt gcattctacg
     3601 caggaacagg attccagatt acagaatcta ttccacaagg tacaaaatta cagtatgaca
     3661 catccaagac gagatgggga gtttatgaca gtattacatc aagagcagca atagaaggag
     3721 gaaaaggtgc ggttgctact tttaatatgg gtgatgatac ttcgtctgag atggatgttg
     3781 tgaacagata tgttaacttt gttaatacac caaaggttgg tagcttatca gtagcaaaga
     3841 aatatgaagg atatgcacca gaaaatgaaa cctttggatt tacagtattg gtagatttga
     3901 caggccacga ttactatgat tcatataaac tgaaatatac tggtactcaa aatggaacaa
     3961 cagatgagaa tggacacttc acattaaaag ttggtgacac agttacattt gcaggtattc
     4021 cagcaggtgc tacttataag gttgttgaag atagcccaca agcaggcgat acatgggtac
     4081 aggaaactac atctgatgta actggtaaaa ttgaagccga tgttacatct gcagcagttg
     4141 taacaaataa gacaaaaaca actgtaaaag attatgtaat ctatgcagaa gctggaaaga
     4201 cagttactta tgcacctgat ggtgtaacta ttacagaact gactgctcaa actacaggtg
     4261 atacagttat caatactaat gtaaaaggag gaaagggtga atttactcca gaatctccaa
     4321 atgaaaagta tgttgtaaat tacacgggaa ccactactaa taatggtaat tttacaggta
     4381 caattactgt atatacatat aaggcaactg ataaggttta tgtattcgat tacggtttag
     4441 agtcaaacat tgcagatgca actactgggg atggcttatt ccaggacggt acattttata
     4501 atgataaagc caaagataca gttgatgata ccactgcaaa actggatcag attacttcgg
     4561 aagcaagtga tattgatgat aggcagacag agataacggg taatcagaat gcaatcaacc
     4621 gcgatggttc agcagaaggt gaagtaacat tcaagccaat tgcgttcatg gataaggttg
     4681 agaagtacac ttatacagca aatattacta aggtggatac agaatttaat agtgctaacc
     4741 cagaaactgg cacaacagtc catggtacaa ttaagacaat gccggcaaac gttgtttact
     4801 atgaagataa cttcaacgaa aaagcaaata gtagtaacag tgcagtaaag attatttact
     4861 cagaaaataa tacatctaaa gatggaacgg acgtgaagct tgagcagagc aatgaccaga
     4921 gcgaacagta tggtcatgat aatgcatatg caaatggcga caaatacagc agcggctcat
     4981 ctacaaagat ggaaaagagt gcaacagcaa catttacctt caagggaact ggatttgata
     5041 tcataagcag aacaaatacc gaaacaggaa ccatcggggt aaaggtatat aagggagaaa
     5101 aagcaagtgg agaacctata agaaatattc ctctgattac atattacgat gacggagatt
     5161 tatatcaggt accagttatt catgaaacag attttgacta tggaacttac acagttgtgg
     5221 tagaagttaa atcttataat ccagacggaa tcgtgttcta tcttgatgga gttcgtatct
     5281 atgaaccatt agatgatcag aaatacacat atgaggaagg tactacatat gattcagata
     5341 attatctcga atcagaagtt gacgcacaca tatatgaaat acgaccaatg atcatcggaa
     5401 atacagtaga cggaaaaact gctaatcatg caatgctgat gcagtacacg ccaggaggaa
     5461 acgtagttct gtctgcagga ggaaatacag tcgttgaaac attaaacgga attgttccgg
     5521 aaggagcaac agaaacaaca gatgattttg aaagatactg gaagtgggga ccaaataatg
     5581 aattatatct ggaaccagga aatgcagttg gattcttaat cccggctgac atctatgact
     5641 cgacaaaacc atatgcaaca ttccagattg gggcaaaggc aacatccaat aaggcagtaa
     5701 cactgaaaac aattcttccg gatggaacag aagcaaaaga ttctacaatt acagtaaact
     5761 ctgcaacaga tatgtactat aagatcaatg ttacagacga aatgaaaacc aaagatggaa
     5821 aatattatca ggtagtaata gcaaacacag atggtggaat ggtatctctt acaaatatta
     5881 agagtacctg cgatccaatt gattttggtg taccagctgc agatactacg gcaatgagaa
     5941 tgatggcagc cagcatgata tccgcatttt caacgaaaga tgaagtagta agtgaagcag
     6001 catttgcgac tgtagtacgt tcaggaagag atgcaacgct tgctgtaaca tcaacagtag
     6061 gagtggagaa attaaagatt acggattcca atggtcaggt aatggataat tctacattga
     6121 atatcagtta tactgataag gttttaaatg gaaacaagct gcgtacatgg agagtaaaat
     6181 tcaaaccgaa cctgaaacga ggaaaatata agtacacagt agaaggaatc acagctgaaa
     6241 acaaagcaac agttagaatt ggaactccaa cattaactgt aaggtaaagg agaacgattg
     6301 tcatgaaaaa gaaatatagc aaaccctgca ttgcagtaga aaactttgtg ttacaggaat
     6361 ttatagctgg aagttgttca gttaaaatga attatgcaaa tgatacatgt gtaactgaag
     6421 ataaactgac gactggtgga attgatgata aactggcagc acagattaaa ggtattattc
     6481 atgaatatca atatttccaa tctacatcca catgttctaa tgaatacaaa ggtacagatg
     6541 ccaccgatgg tgtgtgctat tttacagcga caaatgcaat atttgcgtca taagaactat
     6601 atacaagaaa agaactgtca ttagacagtt cttttcttgt gcaatccaac ggttagaatt
     6661 ggaactccaa cattaactgt aaggtaagaa ttaaatagaa tcgataagac cgcatacagt
     6721 attgcggtct ttatcgctat aaaggaaaaa tatgaatgaa ataactattc aaatcgcaaa
     6781 tataaatttt tgcatagaat gtaaagatga atttgaaatt gtggattact ttaaaatatt
     6841 ccaaaataca aataaagaaa aaaatgcatg taatgtacat tatcaggtaa aaaaaataga
     6901 acaatcaatt tttttggaaa atgaaccggt ttatcaaaat gaacgcatga ccgtatatcg
     6961 cattggttcc gttgaatatc ggcaatttcc gtggtggaat gacgaggcaa attatccaat
     7021 gacattaaag catgatatca atcagccaga tgaatatgag tttttgttaa ctgcaccaca
     7081 gatggaaatg ttcaaaaata aattgcattt tggaacgtat ctggcgttgg aaagggtaat
     7141 gcttgattat gattgctttc aattacatgc gtcagtgatt cgtgtgaatg ggcatggaat
     7201 cttattttct gctccatcgg gtacaggaaa atcaacacaa gcggacttgt gggaaaaata
     7261 tgaaaatgca gagattataa atggagatcg tggaatgatt cgtaagcaag aggatggtac
     7321 atttcaggtt tatggatcgc catttgcagg ttcttcacaa ataatgacaa cgatgtctgc
     7381 accggtaaaa gcggttgtgg tattatcaca agcaccgcat aataaggttt gtagactcgg
     7441 tgtattgaag gcatttacaa agatatatag agaaacaacg ataaatgcat gggatacaga
     7501 atttgtaatg aaaatgacag agttattgaa ccaatttgta aaaagaatac ctgtttatca
     7561 tttggaatgt cggccggatc aggatgcagt agaggtactc aaaaaggaaa ttttctgtga
     7621 taattagata aaagtttgta aattaagcga agatacgtta tactaggact gcatatatac
     7681 aaatttcaca atatagagtt aggagaatac aatggtgaaa ttacagaatt cagaaaataa
     7741 gaaaaaaaca aagaaagttg ttttgctggt aggtgttatt ataattgtga ttattggaat
     7801 attactggcc ctcaagctta caaagaatga ttcgaaagaa aagtctgcca cagaggcaga
     7861 tgcatatgaa attgttaaac ctggaaagga taccctggat gttagtaaga ttcagggata
     7921 ttcagccaaa gtaggtgtag aagacaagaa ggaagaagac acaaaagaaa aagatgactc
     7981 tgacaaaaaa gatgattcta aggagacgga aaaagcagag caaatcgttc tttccgattc
     8041 gaacctcacg gttgagtcca tcggtgctta ttccggttct tttatagaag atggaagtga
     8101 cgaggcgaca aagaacgtaa cagcgatgct gattacgaac aattctgacc agatgcttca
     8161 ggttgcactg attgattttc aggtaaatag caatgagacg gcgagtttta aggtgacgaa
     8221 tcttccggca ggaacttcta cgctggtact tgagagcaat aagcgggagt tttcagataa
     8281 agatacttat acatatggca atgcggctac gggatatatg gatcagccga cgctcgaaga
     8341 ggataaggta gagttaaaga cagagaatgg aaagattaca ctgaagaata agacggacaa
     8401 agagcttaag accgtttatg tatattataa gtatatgcag attggcggtg cttatcttgg
     8461 aggaattact taccgtacac catttgaaaa tgtgggtgca ggcaaggaag ctgaggcagt
     8521 tgcggcacat tttaatccgg acagcagtca gattatggga gtacagatac ttgagaatta
     8581 aaagagattg gggaataagt tcatgaagaa acaacaagca ccaatgcagg cgcagcttag
     8641 aaaatatctg tatcagaagg cggcacacaa taaagtgccg ctttccggta catttgaatt
     8701 gacaccgaga tgcaatatga attgcaggat gtgttacatt cgaatgagtg aagcagagat
     8761 gcgggcaagg ggaagagagt atacagcaga agaatggatt gagatgggaa aagcctgtgc
     8821 aaaagaggga atgctcttct tgctgctgac gggcggggaa ccatttctta gaaaagattt
     8881 tagacagatt tatacagagt taaagaagct ggggttactc atctcaatta atacgaatgc
     8941 gacattgatt gatgaggaga ccgtggagtg gttaaagaag gatccgccga tgaaggtgaa
     9001 tgtgacactt tatggtggtg gaaatgagac ttataaaaag ctgtgtggac atccgaccgg
     9061 atatgatgca gctacgaagg cgattgatct gatgcacgat gcgggcattt ttgtgaatat
     9121 caatgcgagc tttacgaagt acaatctgga tgatatggag gatatttttg catttggcaa
     9181 gagaagggag atccaggtga atgcggcgac ttatatgttt ccgccggtac gtagtgcgaa
     9241 ggacggcgtg acggatgatg cggtgcgttt tacagcagaa gaggctggaa gagcgagagc
     9301 gatggcggat aagtaccgcc tgtctaagga ggagtttgag attcgattga aggcactcca
     9361 tgaaggaaga gatgacttta tgggcggtga ggaagagtgt gagcgtaccc cggatgagaa
     9421 gatgggttgt atggcgggac ggtcttcatt ctggatgaca tgggacggac gaatgacgcc
     9481 ttgcggcatg atgaatgagc cggtagccag accatttgag attggctttt cggatgcatg
     9541 gaagtcaatc tatcaggcga cggatgagat tttgctgcca tctgaatgca agaactgcaa
     9601 gaagcgtttt gcgtgtatga tgtgcggggc gcttacgatt gcggaaggtg gcggatgcag
     9661 ttataagaag ccggagtatt tgtgccggca gacagaggtg ttcctagaag agatggagaa
     9721 agaataccag aaacgggaaa caggggtatg atgacgaata cacaaaaaga gctgttacag
     9781 gcacttcggt gctttatgca gggggatgag gaataccatc ttccggaaag gttttcacag
     9841 ctaaaggagc tgtgtgacct tgctgcgatg cataagattt tagcaattat atatgagatg
     9901 atccggaggg attcggtgct ccttttagag gagaatgcgc cacttgctgc gaggtggaag
     9961 aagagtgcga ttgcggaagt gatgctgcag gtgcaaagga cggctggttt tctggagctg
    10021 tatcagaagc ttcagaagga aggggtacat ccgctggttg tgaaggggct gatttgccgg
    10081 tctttttatg aaaagccgga ctttcggata tcagcggatg aagatctgct gcttaggaag
    10141 gaagagtttg agacctttga ctgcattttg ttagaggaag gatataagag gcaggagctg
    10201 gatcctaagg atctgccgta tgagattcca tatctgaatc cgagaaatca ggtatatata
    10261 gagcttcact tttcgttgtt tgcagaaggc gagggtgcat atggtcatct gaatcaggaa
    10321 tttgcagggg catttgaccg atgcatttgt gagcagattg agggagtgga tattaagaca
    10381 ctttcgccga cggaccatat gttttatctg atctgtcata gttttaagca ttttttacat
    10441 agtggatttg ggatcagaca ggtctgtgat atggtgatga tggcaaagca ttacacgacg
    10501 cggattgact ggagagaaat tcaggataag cttgcacagc ttcgaatgga tacatttttc
    10561 agtgctctgg caaagattgg cagagagtat ctgggatgct cctgggagaa aaccggatat
    10621 gtggattata cgcaggagag tgtggactgt atgccgcttc ttgtggatct gctggaaggc
    10681 ggtgtgtatg gcgggagcac gatggcgaga aggcacagcg cgaatatgac gctggaagct
    10741 gctaggagag gcaaaaaggc gacggcgtcg tcggtttggt catcgttgtt tccgggtgtt
    10801 tcttatatga aggggcatta tgtgtggctc tgtaagtatc cgtggctgct tccggcagca
    10861 tgggtgatgc ggctgtttgg atatgcggca gacaggaagc atacagagga tcagagtagt
    10921 ttagagattg gaaataaacg tgtggaactt cttcggaagt atcatgtgat agattagggg
    10981 acagatatat gaaggtgata gatacaagag aatatgtgtc ggttctgaag caattgacgg
    11041 acgatggacg ggaagtcagc atgcggattg cgggaaatag tatggcgcca tttctgattc
    11101 atgagcgtga tacgatcttc tttcggaagc cggaggcaaa actgaagaag ggcgatatgg
    11161 tgttctttaa aagaagaaac ggacagtata tcatgcacag gattcaccat gtgaagccgg
    11221 atgggtatta tatcgtgggt gatgcgcagt gtatgattga gggaccggtc gcaggggaac
    11281 agatatttgc ggttgtgacg aaagtcataa gaaagggaaa gacgatacag ccgggggact
    11341 tctggtggga gttctttcgt catgtgtggc tgcatatgat tccacttcga agaccggtga
    11401 tggctcttta tacgaagctt ctttttagag gaggcagatc atg
//
