LOCUS       c00126_gnlPro..        11561 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KCOEMNOA_126.
ACCESSION   c00126_gnlPro..
VERSION     c00126_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 16:07:01
            Original ID  :: gnl|Prokka|KCOEMNOA_126
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11561
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11561
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[7254:10198]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      7255..10198
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
     cand_cluster    1..11561
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /kind="single"
                     /product="Others_HGD_unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..11561
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Others_HGD_unassigned"
                     /region_number="1"
                     /rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1,
                     HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and
                     minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2,
                     AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF,
                     ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C,
                     Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and not (minimum(2,
                     [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /tool="gutsmash"
     CDS             562..1410
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP_bind_3"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg126_1"
                     /sec_met_domain="ATP_bind_3 (E-value: 6e-08, bitscore:
                     21.6, seeds: 28, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENKLEHLKEYLKGLGSVAVAFSSGVDSTFLLKVAHDVLGDKAIA
                     ITAQSCSFPKRELNEAKAFCEKEGIQHVICQSEELEIEGFSKNPPNRCYLCKKELFEKI
                     GDIAKKNGIEYIAEGSNMDDNGDYRPGLIAVKELGVKSPLREAKLTKAEIREYSKELGL
                     PTWDKQSFACLSSRFVYGETISEEKLGMVEKAEQLLLDYGFHQVRVRIHGSLARIEIMP
                     EEFPKLLEKNVREDIAKKFKEYGFTYVTMDILGYRMGSMNETLGENDKTTADSSLKGKN
                     E"
     CDS             1407..3194
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M24"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg126_2"
                     /sec_met_domain="Peptidase_M24 (E-value: 5.5e-43, bitscore:
                     136.0, seeds: 437, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVKERIAALRARMKETGIDAYLIPTDDFHGSEYVGEYFKCRKYI
                     TGFTGSAGTAVIMQDMAGLWTDGRYFIQAADQLEGTGITLFKMGEPEVPTVHEFLKKNL
                     TQGRCLGFDGRTVSAKEAAELEKMLDENGVSLSVDHDLAGDIWENRPVLSCEPVTELDI
                     KWAGESRADKCARIRKAMEKKGADLFVLTSLDDIAWLLNIRGGDIHCCPVVLSYLVMTK
                     TEIRLFANEKAFQTDVLEALEKDGVTLFPYDSIYEYVKTFKKDKKVLLCKKKVNSRLVS
                     NIPADTRILDEENLTLLPKATKNPVEVENERIAHIRDGVAVTKFIYWLKKNVGRIPITE
                     LSAAEKLYEFRSEQEDFIDNSFDPIIAYGKHAAIVHYFATPETDIPLEPSGFLLADTGG
                     HYKEGTTDITRTIVMGPTTEEEKKYFTAVLRGTLNLGAARFLHGCTGVNLDILARQPLW
                     EMGEDFKHGTGHGVGYLLNVHEGPNSFRWKIVPGGNAVLEEGMITSDEPGYYREDGFGI
                     RHENLMVCKKAEKTEYGQFMCFEFLTMVPFDLDGVVPELMSVRERNLLNDYHAQVYEKI
                     SPYLNEEEKEWLKDATRAI"
     CDS             complement(3282..5048)
                     /gene_functions="resistance (resist) ABC_efflux (Score:
                     283.5; E-value: 2.1e-86)"
                     /gene_kind="resistance"
                     /locus_tag="ctg126_3"
                     /transl_table=11
                     /translation="MSRSTIKDPAKSKSSETFFKVLRFIGRYRFLLILSITLAAVSVIL
                     QLYVPILFGNAIDQVIAQHQVNFEMMWYYLSRILVMVILSSAATWLMNVINNRMTYQTV
                     KDIRAKAIRHIQVLPLSYLDGHSTGDIISRIIADTDILSDGMLLGFTQLFSGIVTIIGT
                     LIFMFSKNFWITLMVIVLTPVSFLVAKFISSHTFQMFRKQSDARGRQTALIEEMIGNQK
                     VVQAFGYEEKSSERFAKVNEELQECSLKAVFYSSLTNPSTRFVNNVIYACVALVGAFII
                     PGGRLTVGGLSVLLSYANQYMKPFNDISSVVTELQNALACAGRIFDLLEEEPEVAEASE
                     TLKDVKGEVDIKNVCFHYDESKKLIEDFNLHVKPGMRVAIVGPTGCGKSTFINLLMRFY
                     DVNFGSISVDGKPIRDITRHSLRSSYGMVLQETWIKNGTVRDNISIGKPEATDTEIIEA
                     AKLTHSWEFIRRLPKGLDTMLNEDSLSQGQKQLLCITRVMLCLPPMLILDEATSSIDTR
                     TELQIQEAFERMMEGRTSFIVAHRLSTIRNADLILVMKDGSIIEQGTHDELIAKGGFYH
                     TLYNSQFAKVSE"
     CDS             complement(5045..6859)
                     /locus_tag="ctg126_4"
                     /transl_table=11
                     /translation="MRSLAVYLKNYKKESILAPFFKFLEVVFDLIVPIVIAQIIDVGIA
                     NHDNKYIVQRFFILILMAALGLASSITAQFFAAKASVGFATKLRQAVYDHVQHLSFTEL
                     DTLGTDTLITRLTDDINQVQNGLNMGLRLLLRSPFIVLGSMVMAFTIDFKCALVFAVAI
                     PFLFLVVFVIMFLSIPLFKKVQGKLDTVTGLTRENLTGVRVIRAFCREKEAVAEFDTRN
                     QELTKLNLFVGKLSALLNPVTYVLINIATVILIQKAGVEVNLGGMQQGQVVALYNYMAQ
                     MIVELIKLASLIITLNKSAACAGRVADILKVKSTMDYPSSSTYSAQISKDLATATADAS
                     LSENAIVFNDVTFEYSKAGAPSLSHISFSVKKGQTVGIIGGTGSGKTTLVNLISRFYDA
                     SKGTVLLDGQNIENYTRSDLRSRIGVVPQKAALFKGSIRDNLKWGREDASDEDLWQALT
                     TAQGKEVVEGKPGQLDFMLEQNGKNLSGGQKQRFTIARALVKKPEILILDDSASALDFA
                     TDAALRKSLNRLDWKVTTFLVSQRSSSIQQADLILVLDNGTLAGKGTHAELLRTCDTYR
                     EIYFSQFPEERARYSSVSAGNIMKEVTV"
     CDS             7255..8526
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg126_5"
                     /sec_met_domain="HGD-D (E-value: 8.2e-57, bitscore: 182.2,
                     seeds: 370, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEIIETFGHYVENLTDKKPQSARRLLKTGWEAQNLKFRYMQDKRL
                     MPADRHLANLMMDTMLRPLQKPEDSVIVSIFTPCEMMQEVGLHPYNVEGFSCYLSASKA
                     ERAFLQQAENQGIAETLCSYHKTFLGAAQKGLLPKPKCIVYTNLTCDANLLTFRTLADF
                     YQVPVFAIDVPWNQTKENVQYVADQLRDLKVFLEKNTGKTISEDRLKERLVCSKRTLEN
                     YRKYQQLRADRYVPSDLVTPLYAGMTNNILLGTAEEEKYTQMLLEDIKKAPAAKGKHIY
                     WMHTIPFWSDAVRQELCFSEKAQIVGCELAETCEPDFDPENPFEAMARRMVYHALNGSA
                     LRRIEAGIRHAKQAGADGAVWFGHWGCKHTLGAAQLAKKKFEEAGLPLLILDGDGCDRS
                     HGGEGQTSTRLGAFLEMLGGAENE"
     CDS             8519..10198
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: BcrAD_BadFG"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg126_6"
                     /sec_met_domain="HGD-D (E-value: 2e-17, bitscore: 52.8,
                     seeds: 370, tool: rule-based-clusters)"
                     /sec_met_domain="BcrAD_BadFG (E-value: 6.5e-66, bitscore:
                     211.4, seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKTYYVCKYTPIELLESLGGECENFNHMPDGFDLADQVSHPNIC
                     GFGKTLLEGVMEGKIKELVLVSCCDTIRSVYDILLESGKLDFLYILDVLHCDSACSRER
                     MAAQLKGLAEAYAQYKGTEFDAGKFRAAFHVQEKITKPHIAVLGARMGQELFEMTSKAM
                     PLPVENDTCVHNRSVGNILPPEDASFDELMDWYAGEILGQIPCMRMMDPTGRKKLYNDP
                     SVAGIIYHTVKFCDFYSFEYADIKNHTEVPLLKIESDYTIQSSGQLLTRLEAFAESIQP
                     ETLEQTIEVDTKGERKMGKGYFAGIDSGSTSTDVVILNKDHEIVTSIILPTGAGAAIGA
                     DRALAEALKEAGLQREDIDALVTTGYGRTAIKNGDKSITEITCHARGAHFLNPEVRTVI
                     DIGGQDSKVIRLDENGAVANFVMNDKCAAGTGRFLEMMARTMEMNLDQMSECGLEFKED
                     ITISSMCTVFAESEVVSLIAQNKATDDIVHGLNKAVAVKTAALTRRVGGEEKYMMTGGV
                     SKNKGLVKTLEEKLGTKLVISDKAQLCGALGAALFAADMADA"
     CDS             10690..11559
                     /locus_tag="ctg126_7"
                     /transl_table=11
                     /translation="MWEAINSFLTTVDNLVWGVPLMVLIMAGGILLTVRLGLLQIRRLP
                     LALKWMFKNEEEGDGEISSFAALCTALSATIGTGNIVGVATAVCAGGPGALFWMILAAF
                     FGMATKFSEGLLAVKYRVVAEDGHSLGGPFYYIEKGMGTKWKWLAKIFAFFGVCVGLFG
                     IGTFSQVNGISSAVQNFFDPNKSNCVNIPFLGEYSWAVVISSLILAACVAAILIGGLKR
                     IATVSQIIVPFMAVIYLIFSVALILLNITEIPAAIVTVVKGAFNPSAVTGGVVGTMIVS
                     MQKGVARGI"
ORIGIN
        1 gtcagagaac atttaaccga gtatttaaag aaagatataa aatatcaccg agtgactacc
       61 ggagtacatg tctgaaagat atgttgtcat aacatataga ttaataaatt caataaaaat
      121 ctgattatca gtctgaaata agtatctctg ggtgttattt ataatatggg gtagtggtta
      181 attattatgt catgtatgaa tggagaagaa acaaacggag aactgcttca gaaaaagaag
      241 tagacaaact gtaaataaag aagttaagag aggctgttac tttagaaact atttaaagaa
      301 gtaacagaag tcggggaagc gttagaaaag atacaagaaa cataaatcaa tattgttcgt
      361 tctattttca gtaacacatt tcgcaatgcg aaaaataggt tgctgaacag tcgttgccta
      421 tattataatg aagctatagc accctgttaa ataatacatt tgagaaagtt caactttcac
      481 gctctgttaa gccggatcaa tatacattat ttacgaggag tgctacaggt acaataaaaa
      541 acggacaaga ggcagactga tatggaaaat aaactggaac atttaaaaga atatctgaag
      601 ggacttggca gtgtagcagt tgctttctca agtggagtgg attctacatt cttattaaaa
      661 gtagctcatg atgtgctggg tgataaggcg attgcgatta cggctcaatc ctgttctttc
      721 ccgaaaagag agctgaatga agcgaaggca ttctgcgaga aagaggggat tcagcatgtg
      781 atctgccagt ctgaggaatt ggagattgaa ggattttcaa agaatcctcc gaacagatgt
      841 tatttatgta aaaaagaact gtttgagaag attggcgata ttgcaaaaaa gaatgggatt
      901 gaatatattg cagagggatc aaatatggat gataacggcg attacagacc aggtctgatc
      961 gccgtaaaag aacttggagt taagagcccg ctacgtgagg cgaagctgac gaaagcggag
     1021 atcagagaat actcaaagga actggggctt ccgacttggg acaaacagtc atttgcctgt
     1081 ctgtcctcca ggtttgtcta tggagagacc atcagtgagg aaaagcttgg aatggttgag
     1141 aaagcagagc agcttttact tgactatgga ttccatcagg tacgtgtccg tattcacggt
     1201 tcacttgcaa gaattgagat catgccggag gaatttccga aacttctgga aaaaaatgtc
     1261 cgagaggata ttgcaaagaa atttaaggag tatggattca cttatgtgac catggatatt
     1321 ctgggatatc gtatgggaag tatgaacgaa acacttggcg aaaatgacaa aacgactgca
     1381 gatagcagcc ttaagggtaa aaacgaatga cagtaaaaga gagaatagca gcacttcgtg
     1441 cacgcatgaa agagacagga attgatgcat atctgattcc tacagatgat tttcatggtt
     1501 cagaatatgt aggtgaatat ttcaaatgca gaaaatatat cacaggattt accggttctg
     1561 caggcactgc ggtgatcatg caggatatgg caggattatg gacggatgga cgttatttta
     1621 tccaggctgc agatcagctg gagggaacag gaattacttt atttaaaatg ggtgaaccgg
     1681 aagttcccac agttcatgaa tttctgaaaa aaaatctgac acagggaagg tgtctgggat
     1741 ttgacggacg tactgtcagt gcaaaagagg cagcagaatt ggagaaaatg ctggatgaaa
     1801 acggtgtgtc tctcagtgtt gatcacgatc tggcaggcga tatatgggaa aaccgtccgg
     1861 tactttcctg tgaaccggtt acagagctgg atataaaatg ggcaggagaa tccagagctg
     1921 ataaatgcgc aagaatccgc aaagcaatgg agaagaaggg tgcagattta tttgtactga
     1981 cttctctgga tgatattgcc tggctgttaa atatacgtgg gggagatatc cactgttgtc
     2041 cggtggttct ttcttatctt gtaatgacaa aaacagagat cagacttttt gcaaatgaga
     2101 aagcctttca gacagacgta ctggaagcgc tggaaaaaga tggtgtgacc ctttttccct
     2161 atgacagtat ctatgagtat gtgaaaacat ttaaaaagga caaaaaagtt cttctctgca
     2221 aaaagaaagt caacagtcgt ctggttagca atattccggc agacacccgg attctggatg
     2281 aagaaaatct tacacttctt cccaaagcaa cgaagaatcc tgttgaggtg gaaaatgaac
     2341 gcattgcgca tatcagagac ggagttgcag ttacaaagtt catatactgg ttaaagaaga
     2401 atgttggaag gattccgatc acagaattaa gtgcagcaga aaagctgtat gaattccgtt
     2461 cggaacagga ggatttcata gataacagtt ttgatccgat tattgcctat ggaaagcatg
     2521 ctgctattgt acattatttt gcaacacccg aaacggatat tcctctggaa ccatccggct
     2581 ttcttctggc agatacagga ggacattata aagagggaac cactgatatt acccgtacta
     2641 ttgtcatggg accgactact gaggaagaga aaaagtactt cacagcagtt ttgcggggaa
     2701 ctctgaatct gggagctgcc agatttcttc atggctgtac cggtgtaaat ctggatattc
     2761 tggcgagaca gccgctgtgg gaaatgggag aggattttaa acatggaacc ggtcatggag
     2821 taggatatct tctgaatgtc catgaaggac ccaatagctt ccgatggaaa attgttccgg
     2881 gtggaaatgc agtgctggag gagggaatga tcacctctga tgagccggga tattacagag
     2941 aggatggatt tggaatccgt catgaaaatc tgatggtctg caaaaaagct gaaaaaacag
     3001 agtatggtca gtttatgtgc tttgaatttc tgactatggt accttttgat ctggatggag
     3061 tggtgccgga actgatgagt gtccgggaac gtaaccttct caatgattac catgcacagg
     3121 tatatgagaa gatttctccg tatttgaacg aagaagaaaa agaatggctg aaagatgcta
     3181 cccgggcaat ctgataaaaa taaaaaaaca ttttacaaaa tcaaaaagag gaacagccgt
     3241 gatggacagc tgttcctttt tgatttatta tctggcttgt tttattcaga aacttttgca
     3301 aactggctgt tatataaagt atggtaaaat ccaccttttg caatcagctc atcatgagta
     3361 ccctgctcaa tgatacttcc gtctttcata acaagaatca gatctgcatt tcggatggtt
     3421 gaaagcctgt gagctacgat aaagcttgtt cttccctcca tcattcgttc aaacgcttcc
     3481 tgaatttgta attctgttcg tgtatcaata ctggaagtgg cttcatccag gatcagcatc
     3541 ggaggcagac agagcataac tcgtgtgata cacagcagct gtttctgtcc ctggcttaag
     3601 ctgtcttcgt tgagcatggt gtccagtcct ttaggaagcc tccggataaa ttcccagctg
     3661 tgggtaagct tggctgcttc gatgatttca gtatctgtag cttccggttt tccaatcgag
     3721 atattgtcgc ggacagttcc gtttttgatc catgtttcct gaagcaccat accatagctg
     3781 cttctgagag aatggcgggt aatgtctctg atcggtttgc cgtcaacgga aatagatccg
     3841 aaatttacat catagaatct catcagaagg ttgataaagg ttgacttacc gcatccggta
     3901 ggtcctacaa tggcaacgcg catacctggt tttacatgga gattaaagtc ctcaatcagt
     3961 ttctttgatt catcataatg gaagcacaca ttcttaatat ctacttcacc ctttacatct
     4021 ttcagtgtct cagaagcctc tgcaacttcc ggttcctcct ccagcagatc gaagattctg
     4081 cctgcacagg caagagcatt ctgaagttct gtaacaacgg aactgatatc attgaatggt
     4141 ttcatatact ggttggcata ggagagaagt acggaaagtc ctccgactgt cagtctgcct
     4201 ccagggataa tgaatgcacc caccagtgca acacaggcat aaataacatt attgacaaaa
     4261 cgggtggaag ggtttgtcag gctgctgtaa aaaacagcct tcagactgca ttcctgtaat
     4321 tcttcgttaa cctttgcaaa gcgttcagaa gatttttcct catatccaaa agcctgaaca
     4381 accttctggt ttccaatcat ctcttcgatg agagcagtct gacgtcctct ggcatcgctt
     4441 tgcttccgga acatctggaa ggtatgggaa gaaataaatt tggccaccaa aaagcttacg
     4501 ggggtcagga caatgaccat caatgtaatc cagaaatttt tggagaacat gaagatcagt
     4561 gttccgatga tcgttacgat tccggaaaaa agctgggtaa atccaagcag cataccatcg
     4621 gatagaatat ctgtatctgc gataatacgg ctgatgatat ctccggtact gtgtccgtca
     4681 aggtaagaga ggggaagtac ctgaatgtgt cggatggctt tggcacggat atcctttact
     4741 gtctggtagg tcatgcggtt attgatcaca ttcataagcc acgtggcagc agaagagagg
     4801 atgaccatta caaggatacg tgacaggtaa taccacatca tttcgaagtt tacctgatgt
     4861 tgggcaatga cctgatcaat ggcatttccg aacaggatcg ggacatacag ctgaaggata
     4921 acggaaactg ctgccagtgt gatactgagg atcagcagaa aacggtatct tccgatgaaa
     4981 cgcagtactt taaaaaaagt ttcgctgctt ttgcttttag caggatcttt tattgttgat
     5041 ctgctcatac agtcacctcc ttcattatat tacctgcaga tacagaggag tatctggctc
     5101 tttcttccgg aaactgagag aagtagattt cccggtaagt atcacaggta cgcagcagtt
     5161 cagcatgagt acccttacct gccagagtac cgttatcaag gacaaggatt aggtctgcct
     5221 gctgaatgct ggaggaacgc tgggatacta gaaatgtagt tactttccag tcaagtctgt
     5281 tgagagactt acgcagtgct gcatcagtgg caaagtccag ggcactggca ctgtcatcca
     5341 ggatcaggat ttcaggtttt tttaccaggg cacgggcaat ggtaaatctt tgtttctggc
     5401 cgccggaaag gtttttaccg ttctgttcca gcataaaatc aagctgtccc ggtttaccct
     5461 ctactacctc ttttccctgt gctgtggtaa gtgcctgcca tagatcctcg tcagaggcat
     5521 cttcccggcc ccatttcaga ttgtctcgga tagagccttt gaaaagagct gccttctgtg
     5581 gaacaacgcc gattctggag cggagatcac ttctggtgta attttcaata ttctgaccat
     5641 ccagcagaac agttcctttg ctggcatcat agaatctgga gatcagattt accagagtgg
     5701 tttttccgct tcctgtacca ccgataatac ctacggtctg tccctttttt acagaaaaac
     5761 tgatatggga aagactgggg gcaccggctt tgctgtactc aaaggttacg tcattgaata
     5821 cgatggcatt ttcagaaagt gatgcatcag cagttgctgt tgcaaggtcc ttcgatatct
     5881 gagcagaata tgtggaggaa gaggggtaat ccatagtaga tttcactttc aggatatctg
     5941 ccacacgtcc tgcgcaggct gcagatttgt tcagggtgat gatcagggag gcaagcttga
     6001 tcagttccac gatcatctga gccatatagt tataaagggc aacaacctgt ccctgctgca
     6061 taccgccaag atttacttct actcctgctt tctggatcag aataacggta gcaatattga
     6121 tcagtacgta agtgaccgga tttaacaaag cggaaagctt tcctacaaag agatttaact
     6181 ttgtcagctc ctgattgcgg gtatcaaatt ctgcaactgc ctctttttcg cggcagaatg
     6241 cacggataac gcggacgcct gtaaggtttt ctctggtcag tccggttact gtgtccagtt
     6301 ttccctgtac ttttttaaac agaggaatac tgagaaacat aatgacaaag acaaccagaa
     6361 acagaaacgg gatcgcaaca gcaaaaacca gggcacattt aaagtcaatg gtaaatgcca
     6421 tgaccatgga cccaagtacg ataaacggac ttcgaagaag aagacgaagc cccatgttca
     6481 gtccgttctg gacctgattg atatcgtcgg taagtcttgt gatcagggtg tctgttccca
     6541 gggtatccag ctctgtaaaa gacagatgct gtacatggtc ataaactgcc tgtcttaatt
     6601 tagtggcaaa gcccacgctg gctttggctg caaagaactg agctgtaatg ctgctggcaa
     6661 gaccaagagc tgccattaaa ataagaataa aaaatctctg gacaatgtat ttgttgtcat
     6721 ggtttgcaat acctacatca atgatctgtg caatgacgat aggcacgatc aggtcaaata
     6781 caacctccag aaatttaaaa aatggcgcca ggatgctttc ttttttgtag ttttttaaat
     6841 aaactgccaa tgaacgcatt ttaaaaattc cttcctttcg taaaaaatct ttcctatatt
     6901 atttcttcct ttttttgaaa aataatacat tcaaaagtgt atcatttgag acttttttgt
     6961 caagaagaat gtgcaaaaac agctgaactt tggagaaaat tcgttactgt tcactccgtt
     7021 cacagtaact tagccaaaat tcattccaga ttgcctgcgg caatggaatt ttggcttgta
     7081 tgtctcggga ttttggcata ttcatgccaa aacacctcgc agaatagtgg tgtgtgaaca
     7141 gtaacgaaaa ttcaacttga cttccccaaa agatattatt aaaatattcc gtggcactat
     7201 ttgtgcactg acaattgata aattattatt accataatga ggaagagaca gactatggag
     7261 attattgaga catttggtca ttatgtggaa aatctgacgg ataaaaagcc tcagtcagcc
     7321 cgccggctgc taaaaaccgg ctgggaagca cagaatctga agttccgtta tatgcaggac
     7381 aagagactga tgcctgcaga caggcatctt gcaaatctga tgatggatac catgctgcgt
     7441 ccccttcaga aaccggaaga ttctgttatt gtaagtattt ttactccctg cgaaatgatg
     7501 caggaggtgg gattacatcc ctataatgta gagggatttt cctgctatct ttctgcaagc
     7561 aaagcggaga gagcattttt acagcaggca gagaatcagg gaattgcaga gacattgtgc
     7621 agttatcata agacatttct gggtgcagcg cagaaaggac ttttgccaaa gcccaaatgt
     7681 attgtttata ccaacctgac ctgcgatgcc aacctgctta cattccgtac cctggcagat
     7741 ttctaccagg tacctgtatt tgccattgat gtaccatgga atcagacgaa agagaatgta
     7801 cagtatgtgg cagatcagtt aagggattta aaagtatttc tggaaaaaaa tacaggaaaa
     7861 acaatctctg aggacagatt aaaggaacgc cttgtctgca gtaagcggac tctggaaaat
     7921 tataggaaat atcagcagct gcgtgcggac agatatgtgc cctctgatct ggtcacaccg
     7981 ttatatgcag gaatgaccaa caatatcctt cttggaacag cagaagaaga aaagtataca
     8041 cagatgcttc ttgaagatat taagaaagca ccggcagcga aagggaaaca catttactgg
     8101 atgcatacca ttccgttctg gtcggatgca gtgcgccagg agctttgctt cagcgagaaa
     8161 gcccagattg tgggatgtga acttgcagaa acctgtgagc cggactttga tcctgagaac
     8221 ccctttgaag cgatggcgag gagaatggta tatcatgcac tgaacggaag tgcccttaga
     8281 aggattgaag ccggcatccg tcatgcgaaa caggcaggag cagacggtgc tgtgtggttt
     8341 ggacattggg gatgcaagca cacccttggt gcagcacagc ttgcaaagaa gaagttcgag
     8401 gaagccggtc tgcccctttt gatcctggac ggtgacgggt gtgatcgaag ccatggagga
     8461 gaaggacaga cttccaccag gctgggagct tttctggaaa tgctgggagg tgccgaaaat
     8521 gaataaaaca tattatgtct gtaaatatac ccccattgag cttctggaat ctcttggcgg
     8581 ggaatgtgag aactttaacc atatgccgga tggttttgac ttggctgatc aggtttcaca
     8641 tcccaatatc tgtggctttg gaaaaacact tctggaagga gtcatggagg gaaaaatcaa
     8701 ggaacttgtt ctggtgagct gctgtgatac catccgaagt gtttatgaca ttctgctgga
     8761 aagtggtaag ctggattttc tttatatttt ggatgtgctt cactgtgaca gtgcctgcag
     8821 cagagagcgt atggctgcac agttaaaagg tctggcggag gcttatgcgc agtataaagg
     8881 tacagagttt gatgccggaa aattccgggc tgctttccat gtacaggaaa aaatcacaaa
     8941 gcctcatatt gcagtgcttg gtgccagaat ggggcaggaa ttatttgaaa tgaccagtaa
     9001 agctatgccc cttccagtag agaatgatac ctgtgtgcat aaccgctctg tgggaaatat
     9061 acttccaccg gaggacgctt cttttgatga actgatggac tggtatgcag gtgagatcct
     9121 ggggcagatt ccatgtatgc gtatgatgga ccccacaggc cgtaagaagc tttataatga
     9181 tccgtctgtt gcaggaatta tttatcatac agtgaagttc tgtgattttt acagcttcga
     9241 atatgcagat atcaagaacc atacagaagt acctctttta aagattgaat cagattatac
     9301 cattcagagc agtggtcagc ttcttaccag actggaagct tttgcagaga gtattcagcc
     9361 tgaaacactg gagcagacca tagaggtcga cacaaaagga gagagaaaaa tgggaaaagg
     9421 ctatttcgca gggattgaca gtggttctac cagtacagat gtggtgattt taaataaaga
     9481 tcatgagatt gtgaccagta ttatcctgcc tacaggagca ggagctgcta ttggagcaga
     9541 ccgtgccctt gcagaggcat tgaaagaggc cggattgcag agagaagata ttgatgcgct
     9601 ggttactacc ggatacggac gtacagctat taaaaatggt gataagagta tcacagagat
     9661 cacctgccat gcaagaggtg cgcatttcct gaatccggaa gtccgtactg ttattgacat
     9721 tggcggacag gacagcaagg tgatccgact ggatgagaac ggtgcagttg caaactttgt
     9781 tatgaatgac aaatgtgcgg caggaaccgg acgatttctg gaaatgatgg cacgtaccat
     9841 ggaaatgaat ctggatcaga tgagcgaatg tgggctggaa ttcaaagaag atattacaat
     9901 ttccagtatg tgtacagtgt ttgcagaatc agaagttgta tctctgatcg cccagaataa
     9961 ggcaacagat gatattgtcc atggtctgaa taaggcggtt gctgtaaaaa ccgcagctct
    10021 taccagacgt gtgggcggtg aggagaaata tatgatgacc ggtggtgttt ctaagaataa
    10081 gggtctggta aagacactgg aagagaagct tggaacaaag ctggtaatca gtgacaaagc
    10141 tcagctttgc ggtgcacttg gcgcagcact gtttgcggct gatatggctg atgcgtaaat
    10201 ttttagttac tgttcactcc gttcacagta acaattttta tacttttttt ataaaagttt
    10261 aattttctat tgacgagttc aaatttaaga gctatagtat accacagtaa cagcaattaa
    10321 cgaggtgaag tttgcaggaa agaggaagcc acacaaaagg ctatacccgc cgaaggagta
    10381 aaactctcag gttccctgga tgcagggaag aactgcaaat ggatcgtttc tctggagaca
    10441 cccgttagat cgggggccga aggtgcaaat aacatggaat gtggataact tcccacaact
    10501 ggttatctga tccgtgtttt gaatctctca ggcaaaagga cagaggatgc tttatcatcc
    10561 ctgctgattc attttaaata tatgaacagt attttctgaa cttctgattt ttgaaacggt
    10621 ctgttattac tttgtttccc agctgtacaa tatattacac tttttaaaag aaaaaggaga
    10681 tttattatta tgtgggaagc gatcaattct tttttgacaa cagtagacaa tctggtctgg
    10741 ggcgtacccc ttatggtcct gatcatggca ggtggtatcc tgttaactgt cagactcgga
    10801 cttcttcaga tacgaagact cccccttgca ttaaaatgga tgtttaaaaa cgaagaagaa
    10861 ggcgatggtg agatttccag cttcgcagct ttatgtacag cactgagcgc tacaatcgga
    10921 accggtaata tagtcggtgt tgcaactgct gtctgcgccg gtggtcccgg agctttattc
    10981 tggatgattc ttgcagcatt cttcggaatg gcaacaaaat tctctgaagg tcttcttgca
    11041 gtgaaatacc gtgtggtagc agaagacggt cacagccttg gcggtccttt ctattacatt
    11101 gagaaaggta tgggaacaaa atggaaatgg cttgcaaaga tctttgcatt ctttggcgta
    11161 tgtgtaggcc ttttcggaat cggtacattc agccaggtaa atggtatttc cagtgcagtt
    11221 cagaatttct ttgatccgaa caaatcaaac tgcgtgaata tcccattcct tggagagtat
    11281 tcctgggcag ttgtaatttc ttccctgatc cttgcagcct gtgttgcagc aatcctcatc
    11341 ggaggtctga aacgaattgc aacagtcagc cagattattg taccgtttat ggcggtgatt
    11401 tatctgatct tcagtgttgc gttgattctt ttaaacatta cagagattcc ggcagcaatc
    11461 gttacagttg tgaagggagc ctttaatccg tcagcagtga caggcggtgt ggtaggaaca
    11521 atgatcgtat ccatgcagaa aggtgtggct cgtggtatct t
//
