LOCUS       c00005_gnlPro..        13098 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NAADOJHN_5.
ACCESSION   c00005_gnlPro..
VERSION     c00005_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 19:55:14
            Original ID  :: gnl|Prokka|NAADOJHN_5
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13098
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13098
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[340:3098]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      341..3098
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
     cand_cluster    1..13098
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /kind="single"
                     /product="Putrescine2spermidine"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13098
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Putrescine2spermidine"
                     /region_number="1"
                     /rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /tool="gutsmash"
     CDS             341..1531
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Sacchrp_dh_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Sacchrp_dh_NADP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg5_1"
                     /sec_met_domain="Sacchrp_dh_C (E-value: 1.4e-38, bitscore:
                     126.6, seeds: 375, tool: rule-based-clusters)"
                     /sec_met_domain="Sacchrp_dh_NADP (E-value: 3.7e-35,
                     bitscore: 114.2, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCKALIIGAGGVGTVVTQKIAANPVFTDVMLASRTKSKCDAVAAA
                     IGGNRVKTAEVDADSVPQLCELFRAFKPDIVVNVALPYQDLTIMDACLECGCNYLDTAN
                     YEPKDEAHFEYSWQWAYQDRFKAAGLTAILGCGFDPGVTAIFTAYAAKHHFDEIHYLDI
                     VDCNAGNHGMAFATNFNPEINIREVTQKGRYYENGEWVVTEPHEIHKPLNYPGIGERES
                     YVIYHEELESLVKNYPTIRRARFWMTFGQEYLTHLRVIQNIGMARIDPIIYNGVEIVPI
                     QFLKAVLPDPKSLGANYHGQTSIGCRIKGLKDGKERTYYIYNNCDHEQAFKETGTQAVS
                     FTTGVPAALGASMWAKGLWRGAGVFNVEEFDPDPFLAELGEQGLPWHELFDVNLEV"
     CDS             1959..3098
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Orn_DAP_Arg_deC"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg5_2"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 2.1e-10,
                     bitscore: 34.0, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIDFLKLPSPCYVLDEELLDRNLATVDRVRRESGAEIIVALKACA
                     MWSIFPELAKHSDGATASSAAEARLVFEEFGRPAHTYAPVYTDSNIDEILNCSDHITFN
                     SLSQFRRFGQKALINGISCGLRINPQYSPVETDLYNPCAPGSRLGVTAEQLAAHGGLPA
                     GVEGLHFHVLCESRPEHLQKALEAVETHFGAYLDRIKWLNMGGGHLMTASWYDCDRLIA
                     LLKAFRSRHPNLRLILEPGSAFTWRTGFLVSTVEDIVENGGVTTAMLDVSFACHMPDCL
                     EMPYKPTVIGAHEPADGEKRWRMGGTSCLAGDYCGDWAFDRELKVGERVVFEDMIHYTM
                     VKTTMFNGVHHPAIVIARRDGRTDVIREFGYEDFRNRMS"
     CDS             3132..4424
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg5_3"
                     /sec_met_domain="PALP (E-value: 2.1e-27, bitscore: 89.5,
                     seeds: 146, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENFTPTPYTLECVATGREFEDAGWMFADPQCKEPSLVRTKYARK
                     QIDVKPADWGLYRFSDWMPVRRILKGSSAPVTYKSKGLAAHLGLENLWITFNGWYPAIG
                     ATMSTCSFKETEAYSVCGRAAADERRVLVVASAGNTARAFAKVCSDNNIRLLLSVPYDN
                     IGALWFDQPLNPCVKLISCEKGGDYFDAIHLSDIALKSPGFYAEGGAKNVARRDGMACT
                     VLSAVTTIGRIPDYYFQAVGSGTGAIAAWEANMRLVEDGRFGRNTMKLMVAQNAPFVPM
                     YDAWQAASRKLLPYDDDKARRDAEIIDAKVLSNRRPPYSVTGGLFDALKATGGEVFVAT
                     NAMARKARKLFHELEGVDIYSAAGVALASLVNAVNAGKIEKDATVMLNVTGGGEEHFKE
                     GKELWYLKPSHVFPLEPDENDVVEKVEALFN"
     CDS             4445..5545
                     /locus_tag="ctg5_4"
                     /transl_table=11
                     /translation="MKKGIIALTVSFLAVSAAAQQPVSADRFADAVNHWNKEHGAQTYE
                     RYKPDRFREIADNIVAYQNADGGWPKNLDMLARLDPDSVKAALKPRHRLSTLDNANVYT
                     QVEYLSNVYLLTGDTLYRNSARRGMEYMLSAQYPNGGWRGWDADAVTFNDGIIYGVLST
                     WNEILSGNPHYAWVGDDLKARIRASWDRGIDLILKTQWVQDGVKTVWAQQYDHETLQPV
                     KARAYELPALSAGESADITMLLMRIKNPSPEVVEAVESAAAWFDRTKITGKKVVTVPVP
                     EGLAEDRKIRKDRVVVDDPEAAPMWPRYSELSDNRPFFATREGKKVYDLREVPAERRVG
                     YSWYGTWGNKVLKKYPEWLRRLTEKK"
     CDS             5701..7683
                     /locus_tag="ctg5_5"
                     /transl_table=11
                     /translation="MENIQTKQYPCFKRWSRKNWSVFASLHRYVTIGVLSVGMSILLLA
                     TQGASAQTADTTAVLKTLRIREVGVTGSQTAPARNAQSHTPLFDRKAQAPAPVQTLEAA
                     LRLAPSVDVRERGGKGTQADIFIRGGSFDQTMVLLNGIDFTDARTGHQSHALPVDLDCI
                     SAVELIDGVPGVGAYAGAVNIRTAPLRPTYLRLEASGGQYGYGYGNLSGAVSAGRFSVL
                     GAASYRRSDGYRHNTDFSNYNAFVRATYDGGRAGFFDLQAGWQDRDFGSNGFYAAYNPD
                     QWEHTATALGSLRWLKTAGRFSLGAAASYRKNFDRYDWTRGTAMNRHNTDNVGAKLWAD
                     CDWAAGVTTVGGDYAFNHIYSTNLGDKLSVPEGHYTHAKARHTGNLWLRHAKRWRHFDA
                     AASAGVSLTPYGTSALWSLSAGYAPAAGLRLEAGAWQSMRLPTFTDLYYTSPAQINNLD
                     LTPEHAVTYRLGVDYLKRSWNLSAQAYYRSGRDIIDWVWREDMGSKWHSEQTSSLDTFG
                     IELAGGYTVSEGFLRRVTLSYGYITTDRNADVIAKSAMDFMRHKAALAVEVHFLRRMSL
                     ALTGSVYDRNGSYTHYPEPGNASLNEERDYKPYFLLDGRLQWEKGICRLYVDATNITDT
                     RYCDIGGIRLPGFWCTGGVTLTIGK"
     CDS             7872..9572
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FTCD_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg5_6"
                     /sec_met_domain="FTCD_C (E-value: 7.3e-66, bitscore: 214.6,
                     seeds: 242, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQRIIECVPNFSEGRDKAVIRQITAAIEASGGVKLLDVDPGEAT
                     NRTVVTFVGEPEAVVEAAFAGVKRAAELIDMRRHKGAHPRMGATDVLPLIPIAGVTLAE
                     CAELARALARRIADELRIPTYCYEAAAFAPERKNLAVCRAGEYEALPEKLAHTASAPDF
                     GARPFDEGVARTGATTVGARDFLIAVNFNLNTTSTRRANAIAFDVREKGRPVREGNPIT
                     GRVVKDAAGNPVMQPGTLPATKAIGWFIEEYGIAQVSMNITDISRTPLHAAFDEVCRKA
                     DARGVRVTGTEIVGLVPKRALVEAGKYFLRKQRRSTGVAEEEIVRIAVKSMGLDDLKPF
                     DPAEKVIEYLLEAEVPKKRLIDMTCKAFAEETASESPAPGGGSIAAYMGALGAALGTMV
                     ANLSSHKAGWDDRWEEFSDWAERGQAVLAELLHLVDEDTAAFNRIMAVFAMPKSTDEEK
                     AARAAALQEATLYATEVPLRTMKAASRVFEIVRAMASEGNPNSVSDAGVGALAARSAVL
                     GACLNVKINAAGLKDRAVADALTAEADALAAEAVRLEAEVLQIVESKIG"
     CDS             9574..11613
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Urocanase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Urocanase_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Urocanase_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg5_7"
                     /sec_met_domain="Urocanase (E-value: 1.2e-89, bitscore:
                     292.6, seeds: 148, tool: rule-based-clusters)"
                     /sec_met_domain="Urocanase_C (E-value: 4.7e-90, bitscore:
                     293.5, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="Urocanase_N (E-value: 6.9e-60, bitscore:
                     193.6, seeds: 71, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTREEFQNDIRAGIPDRLPAAKPYDKRINHAPKRKDILSDEEKAL
                     ALKNALRYFPVRHHAVLAKEFAEELRRYGRIYMYRLRPDYEMHARPIGEYPARCRQAAA
                     IMLMIQNNLDPRVAQHPHELITYGGNGAVFQNWAQYRLAMQYLSEMTENQTLVMYSGHP
                     LGLFPSHPDAPRVVVTNGMVIPNYSKPDDWERLNALGVSQYGQMTAGSYMYIGPQGIVH
                     GTTITVMNAARKRFTAGCTDTRGMLFVSSGLGGMSGAQPKAGNISGVVSVVAEINPKAA
                     QKRHEQGWVDELHEALDELIPRIRQAVKAKEVVSMAYVGNVVDLWERLAAEEIPVDLGS
                     DQTSLHNPWAGGYYPVGLSYEASNKMMAEEPGRFRECVQESLRRQVDAINKLTDRGMYF
                     FDYGNAFLLEASRAGAAVTGEGGRFRYPSYVQDIMGPMFFDYGFGPFRWVCTSGKPEDL
                     ETTDSLAAEVLEEIRKTAPDDIRGQLDDNIHWIREAGRNRLVVGSQARILYADCEGRVK
                     IAEAFNRAIAEGRITAPVVLGRDHHDVSGTDSPYRETSNIYDGSCLTADMAVQNVIGDA
                     FRGATWVSIHNGGGVGWGEVINGGFGMVIDGSEDAGRRIREMLLWDVNNGIARRSWARN
                     EGAVEAIRREMDRTPGLRVTLPVFADEELVREALNEQGGASDKL"
ORIGIN
        1 ggctcgaacc caggacccca acattaaaag tgttgtgctc taccagctga gctacggaat
       61 ctccgtgtgc caaaatgaga atcgtttccg ttttggtggt gcaaatgtac ggatttattt
      121 ttaaaatcca atacccggcc tgcaaatttt gcgcaaaagt gtgttttttg cctttccggc
      181 tgccggatgc cgcctgcagg cgataggcgt ccgggcatct tccggcggtt tcggccggcc
      241 gggatcgtga aatttggcgt gcggattttg ttttgccgaa ataaaaggat atttttgtag
      301 gcgttaagat gaaatctaac ttttaaaacc gaataattct atgtgtaaag cgctgataat
      361 cggagccggc ggcgtcggaa cggtggtgac gcagaaaatc gcggccaatc ccgtcttcac
      421 ggacgtgatg ctggccagcc gtaccaaatc caaatgcgac gccgttgcgg ccgccatcgg
      481 cggcaaccgc gtgaagaccg ccgaggtcga cgccgacagc gtgccgcagc tgtgcgaact
      541 gttccgcgcg ttcaaacccg acatcgtggt caacgtggcg cttccgtacc aggatctcac
      601 gatcatggac gcctgcctcg aatgcggctg caactacctc gatacggcca actacgagcc
      661 gaaggacgag gcgcatttcg aatactcgtg gcagtgggcc tatcaggacc gcttcaaggc
      721 cgcgggactc acggcgatcc tcggctgcgg tttcgacccg ggcgtgacgg ccatcttcac
      781 ggcctatgcc gccaagcacc atttcgacga aatccactac ctcgacatcg tcgactgcaa
      841 cgccggcaac cacggcatgg ctttcgccac gaacttcaac cccgagatca acatccgcga
      901 ggtgacccag aaagggcgtt attacgagaa cggagagtgg gtggtgaccg agccgcacga
      961 gatccacaag ccgctcaatt atccgggcat cggcgagcgc gagtcgtacg tcatctacca
     1021 cgaggagctg gagtcgctcg tgaagaacta tcccacgatc cggcgtgcgc gcttctggat
     1081 gaccttcggt caggagtacc tgacgcacct gcgcgtgatc cagaacatcg gcatggcgcg
     1141 tatcgacccg atcatctaca acggggtcga gatcgtcccg atccagttcc tcaaggcggt
     1201 tcttcccgat cccaagtcgc tgggcgccaa ctatcacggc cagacctcga tcggctgccg
     1261 catcaagggc ctgaaggacg gcaaggagcg cacctactat atttataaca actgcgacca
     1321 cgaacaagcc ttcaaggaga ccggcacgca ggctgtgtcg ttcaccacgg gcgttccggc
     1381 ggctttgggc gcttcgatgt gggccaaggg cctctggcgc ggcgccggcg tgttcaacgt
     1441 cgaggagttc gatcccgatc cgttcctcgc cgagctgggc gagcagggcc tgccgtggca
     1501 cgagctgttc gatgtgaatc tcgaagtgta ggtttttgaa gattgcggcg cagatgccgc
     1561 acatccctca aaatccccgg atggatagtg ccgaagtacg tcccatccgg ggatttttca
     1621 cgatgcacga cagatgcacc gcaccgatcg aaaaccgcag cgggattttc cgctcctcca
     1681 aaatcaaaac tgtcgtatcg ttttccgcag aaccgctttt cccgaaatgc ccctgccggc
     1741 gaccggctcc gatgcttatt tccggaccgg gtttcgcaag cgataagtat aaatgcgtat
     1801 tttcccgaaa accaagcctg cgcagcgtgg ttttcaggag gtttttgcta cttttgcaac
     1861 tgttttggac gttttcgttg agcgagggca gagccgggct tgcccggatt atgccgagcg
     1921 gagaaaacga aggatgaaat ccaactaaaa acaattcgat gattgacttt ctgaaactgc
     1981 cttcaccgtg ctacgtcctc gacgaggagc tgctggaccg gaacctggcg actgtcgacc
     2041 gtgtgcgccg ggaatcgggc gccgaaatta tcgtcgccct gaaggcctgc gccatgtgga
     2101 gcatttttcc cgagctggcg aagcattccg acggtgcgac tgcaagttcc gccgccgagg
     2161 cgcgtctcgt tttcgaggag ttcgggcgtc ccgcccacac ctacgccccg gtctacacgg
     2221 actccaatat cgacgaaatc ctcaattgca gcgatcatat cacgttcaat tcgctgtcgc
     2281 agttccgccg cttcggccag aaagccctta tcaacggcat ttcctgcggc ctgcggatca
     2341 acccgcagta ttcgcccgtc gagacggacc tctacaaccc ctgcgccccc ggctcgcggc
     2401 tgggcgtcac ggccgaacag ctggcggcgc acggcggact tccggcgggt gtcgaggggc
     2461 tgcatttcca cgtcctctgc gaatcgcgcc cggagcatct gcaaaaggcg ctggaggccg
     2521 tcgagacgca tttcggagcg tatctcgacc ggatcaaatg gctcaacatg ggcggcggcc
     2581 acctgatgac ggcctcgtgg tatgactgcg accgcctgat cgctctgctg aaggcgttca
     2641 ggtcccgcca tccgaacctg cggctgattc tcgaacccgg cagcgccttc acgtggcgca
     2701 cgggctttct ggtttcgacc gtcgaggaca tcgtggagaa cggcggggtg acgacggcga
     2761 tgctcgacgt gtcgttcgcc tgccacatgc ccgactgcct cgaaatgccc tacaaaccca
     2821 ccgtcatcgg agcgcatgaa cctgccgacg gcgaaaagcg ctggcgcatg ggcggcacga
     2881 gctgccttgc gggcgactac tgcggtgact gggctttcga ccgcgagctg aaggtggggg
     2941 agcgcgtcgt cttcgaggac atgatccact acacgatggt caagaccacg atgttcaacg
     3001 gcgtacacca tccggccatc gtcatcgcgc gccgcgacgg ccgcaccgac gtcattcgcg
     3061 aattcggcta cgaggacttc cggaaccgca tgtcatagac aatattgaat tcagatatac
     3121 gaaacctctt catggaaaat ttcacaccta ccccctacac gttggaatgc gtcgccacgg
     3181 gccgcgaatt cgaagacgcc ggctggatgt ttgccgaccc gcagtgcaag gagccttcgc
     3241 tcgtgcgcac caaatacgcc cgcaaacaga tcgacgtgaa acccgccgac tggggcctgt
     3301 accgtttctc ggactggatg cccgtgcggc gtatcctcaa aggttcgtcg gctcccgtga
     3361 cctataagag caagggcctc gccgcgcacc tcgggctgga aaacctctgg atcaccttca
     3421 acggctggta tccggccatc ggggccacga tgtcgacctg ctcgttcaag gagaccgagg
     3481 cctattcggt ctgcggccgc gccgctgccg acgaacggcg cgtgctggtg gtggcttcgg
     3541 ccggaaacac cgcccgggcc ttcgccaagg tctgctcgga caataacatc aggctgctgc
     3601 tctcggttcc ctacgacaat atcggcgcgc tgtggttcga ccagccgctg aacccctgcg
     3661 tgaaactcat ttcgtgcgag aagggcggcg actatttcga cgccatccat ttgagcgaca
     3721 tcgcgctgaa aagccccggc ttctacgccg agggcggcgc caagaacgtc gcgcgtcgcg
     3781 acggcatggc ctgcacggtc ctttcggccg tgacgaccat cggccgcatt cccgactact
     3841 atttccaggc cgtgggcagc ggcacgggcg ccattgccgc ctgggaggcc aacatgcgtc
     3901 tggtggagga cggccgcttc gggcggaata cgatgaagct gatggtggcg cagaacgccc
     3961 cgttcgtccc gatgtacgac gcctggcagg cggcatcgcg caagctgctg ccttacgacg
     4021 acgacaaggc gcgccgcgac gcggagatca tcgacgccaa ggtgctttcg aaccgccgtc
     4081 cgccttacag cgtcacgggc ggtcttttcg atgcgctgaa agccaccggc ggcgaggttt
     4141 tcgtggccac gaacgccatg gcgcgcaagg cccgcaagct gttccacgaa ctcgaaggcg
     4201 tcgacatcta ttcggcggcg ggcgttgcgc tggcgtcgct cgtcaatgcc gtgaacgcgg
     4261 gtaaaatcga gaaggacgcc accgtcatgc tcaatgtcac gggcggcggc gaggagcact
     4321 tcaaggaggg caaggagctg tggtatctca agccgagcca cgtcttcccg ctcgaacccg
     4381 acgaaaacga cgtcgtggag aaggtcgagg cgctgttcaa ctgatccgtt aaatgaccgg
     4441 gcttatgaaa aagggaatca ttgccttaac cgtatcgttc ctcgctgttt ccgcagccgc
     4501 gcagcagccg gtttccgccg accgtttcgc cgatgccgtg aaccattgga acaaggagca
     4561 cggtgcgcag acctacgagc gttataagcc cgaccggttc cgtgaaatcg ccgacaacat
     4621 cgtcgcctat cagaacgccg acggcggctg gcccaagaac ctcgacatgc tggcccggct
     4681 cgaccccgac tcggtgaagg cggccctcaa gccgcgccac cgcctctcga cgctcgacaa
     4741 cgccaacgtc tatacgcagg tcgagtatct ttcgaacgtc tacctgctga cgggggacac
     4801 cctctaccgc aattcggccc gccggggcat ggagtacatg ctctcggcgc agtaccccaa
     4861 cgggggctgg cggggctggg acgccgacgc cgtgacgttc aacgacggca tcatctacgg
     4921 cgtgctttcg acgtggaacg agatcctctc cggaaacccc cactatgcgt gggtcggcga
     4981 tgacctgaaa gcccgtatcc gggcctcgtg ggaccggggc atcgacctga ttctcaaaac
     5041 ccagtgggtg caggacggcg tgaagaccgt ctgggcgcag cagtacgacc acgagacgct
     5101 gcaacccgtg aaggcccggg cttatgaact ccccgcgctg tcggccggcg agagcgccga
     5161 catcacgatg ctgctcatgc gtatcaaaaa cccctcgccc gaggtcgtcg aggcggtcga
     5221 gtccgcggcc gcatggttcg accggacgaa aatcacgggt aaaaaggtcg tgacggttcc
     5281 ggtgcccgag gggctggcgg aggaccggaa gatccggaaa gaccgggtcg tggtcgacga
     5341 tcccgaagcc gcgcccatgt ggccgcgtta cagcgaattg tccgacaacc gccccttctt
     5401 cgccacgcgc gaggggaaga aggtctacga cctgcgcgaa gtccccgccg aacggcgcgt
     5461 gggctactcg tggtacggta cgtggggcaa caaggtgctg aaaaaatatc ccgaatggct
     5521 tcgccgcctg acggagaaaa agtgacggag ccatgcggcg cggattcgcc gcatgcgttc
     5581 tttttcggaa acgggccgtt gcggtccgtt tttttattac ctttgcgggg ccgaaccgga
     5641 agccagtgca gccggacccg gttcggacgt tttttcactt ttaacccaaa tttcaaacaa
     5701 atggaaaaca tccaaacaaa gcagtacccc tgcttcaagc gttggagtcg caaaaactgg
     5761 tcggtttttg ccagcctcca ccgttatgtg actatcgggg tcctctctgt cgggatgtcg
     5821 atcctgctgc ttgcgacgca aggtgcgtcc gcgcagactg ccgacacgac cgctgttctc
     5881 aagacattgc ggatccggga agtcggcgtc accgggagtc agacggctcc cgcgcgcaac
     5941 gcccagtcgc acaccccgct tttcgaccgg aaagcccagg ccccggcgcc tgtccagact
     6001 ctggaagccg ccctgcgcct tgctccttcg gtcgatgtcc gcgaacgcgg aggcaaggga
     6061 acgcaggccg acatcttcat ccggggaggc tctttcgacc agaccatggt ccttctcaac
     6121 ggcattgatt tcaccgatgc ccgcaccggg catcagtccc acgcgctgcc cgtcgacctc
     6181 gactgcattt cggccgtcga actgatcgac ggcgttccgg gcgtcggagc ctacgccggt
     6241 gcggtgaaca tccgcaccgc gccgctgcgg cccacctacc tgcgcctcga agcctcgggc
     6301 ggccagtacg gctatggcta cgggaatctt tcgggcgcgg tgagtgcggg acgcttctcg
     6361 gtgctcggcg cggcttcgta ccgccgcagc gacggctacc ggcacaatac cgatttctcc
     6421 aactacaacg cattcgtacg ggcgacctac gacggcgggc gggccgggtt cttcgacttg
     6481 caggccgggt ggcaggaccg cgatttcggc tccaacggtt tctatgcggc ctacaatccc
     6541 gaccagtggg agcataccgc cacggccctg gggtcgctgc ggtggctgaa aaccgcaggc
     6601 cgcttttcgc tgggggccgc cgcgagctac cgcaagaact tcgaccgcta cgactggacg
     6661 cgcggcacgg cgatgaaccg ccacaacacg gacaatgtcg gagcgaagct ctgggccgac
     6721 tgcgactggg cggcgggcgt taccaccgtg ggcggagact atgctttcaa ccacatttac
     6781 agcaccaatc tcggtgacaa gctctcggtt cccgaaggcc attacaccca tgccaaggcg
     6841 cgccacacgg gcaacctgtg gctgcggcac gccaagcggt ggcggcattt cgacgcggcg
     6901 gcttcggcgg gcgtgagcct cacgccctac ggcacttcgg ccctgtggag cctttcggcg
     6961 ggctatgccc ccgcggccgg gctgcgcctc gaagccgggg cgtggcagtc gatgcgcctg
     7021 ccgaccttca cggacctcta ctacacctcc ccggcgcaga tcaacaacct cgatcttacg
     7081 ccggaacacg cagtcacata ccgacttggt gtggattacc tcaagcggag ctggaacctt
     7141 tcggcgcaag cctattaccg ctccgggcgc gacatcatcg actgggtctg gcgcgaggac
     7201 atgggcagca agtggcattc cgaacagacg agcagcctcg ataccttcgg gatcgaactc
     7261 gcgggcggct atacggtttc ggaaggcttc ctgcgccgcg tgacgctctc gtacggctac
     7321 atcacgaccg accggaacgc ggacgtcatc gccaaaagcg cgatggattt catgcgtcac
     7381 aaggcggcat tggccgtgga ggtgcatttc ctgcggcgga tgtcgcttgc gctgaccggc
     7441 tcggtctacg accgcaacgg cagctatacg cattaccccg aaccgggcaa cgcctccctt
     7501 aacgaagaac gcgactacaa gccctatttc ctgctcgacg gacgtctcca gtgggagaag
     7561 ggcatctgcc gcctctacgt cgacgccacg aacatcaccg acacgcgcta ctgcgacatc
     7621 ggcggaatcc gcctgccggg tttctggtgt acgggcgggg tgacgctgac catcggcaaa
     7681 taacctctct tttccgggac cggggcgctt ccgcccccgg atttcggtcc ggctgcaatc
     7741 ctggcccggt gcacaaatgc accgggcctt tctgtttttc gcaaaaagcc gcctgttttg
     7801 ttacggtttt ttcggatttc tcccgattat tatttatctt tgaagtatag gaatttaaat
     7861 gcgacgatcc tatgtcccaa agaatcattg aatgcgttcc caatttcagc gagggacgcg
     7921 ataaagccgt gatccggcaa atcaccgcgg ccatcgaggc ctccgggggc gtcaaactgc
     7981 tcgacgtgga ccccggcgag gcgaccaacc gcacggtcgt gaccttcgtc ggcgaacccg
     8041 aagcggtcgt cgaggccgct tttgccgggg tgaagcgggc ggccgaactg atcgacatgc
     8101 gccgccataa gggggcgcat ccccgcatgg gggccaccga cgtgctgccg ctgataccga
     8161 ttgcgggcgt cacgcttgcg gagtgcgccg aactggcgcg cgcgctggcc cggcgtatcg
     8221 ccgacgaact gcgcattccg acctattgct acgaggccgc ggcctttgcg cccgaacgga
     8281 aaaacctcgc cgtgtgccgc gccggggagt acgaggccct gcccgagaaa ctggcgcaca
     8341 cggcatccgc gcccgatttc ggggcgcgtc ccttcgacga gggggtcgcc cgcacgggag
     8401 ctacgaccgt cggggcgcgc gacttcctga tcgccgtgaa tttcaacctg aacaccacct
     8461 ccacgcgccg cgccaacgcc atcgccttcg acgtgcgcga aaaggggcgt cccgtccgcg
     8521 agggcaatcc catcacgggc agggtggtga aggatgccgc gggaaatccc gtgatgcagc
     8581 ccggaacgct tccggccacg aaggccatcg gctggttcat cgaggagtac ggcatcgcgc
     8641 aggtctcgat gaacatcacc gacatctccc ggacgccgct ccacgcggct ttcgacgagg
     8701 tgtgccgcaa ggccgacgcc cgcggcgtgc gcgtcacggg gaccgaaatc gtggggctgg
     8761 ttccgaaacg ggctttggtc gaagccggca aatacttcct ccgcaagcag cgtcgctcga
     8821 cgggcgtcgc cgaggaggag atcgtccgca tcgccgtcaa gtcgatggga ttggacgacc
     8881 tgaagccgtt cgatcctgcc gagaaggtga tcgagtacct gcttgaagcg gaggttccga
     8941 agaagcggct tatcgacatg acctgcaagg cgttcgccga agagacggcg agcgaatctc
     9001 ccgctccggg cggcggctcg atcgcggcct acatgggcgc gctgggcgcg gccctcggga
     9061 cgatggtcgc caacctttcg tcgcacaagg cggggtggga cgaccgctgg gaggagtttt
     9121 ccgactgggc cgaacggggg caggccgttc ttgcggagct tctgcacctc gtggacgagg
     9181 acacggcggc gttcaaccgc atcatggcgg ttttcgccat gcccaagtcg accgacgagg
     9241 agaaggcggc gcgcgccgcg gctttgcagg aggcgacgct ctatgccacg gaggttcctc
     9301 tgcggacgat gaaggccgcc tcgcgggttt ttgaaatcgt gcgcgccatg gcctcggagg
     9361 gcaaccccaa ttcggtctcc gacgccggcg tgggtgcgct ggcggcccgc agcgcggtgc
     9421 tgggggcgtg cctcaatgtg aagatcaacg ccgcggggct gaaggaccgt gccgtggccg
     9481 atgcgctgac cgccgaggcc gatgcgctgg ccgccgaagc cgtgcgtctc gaagcggagg
     9541 tcttgcagat cgtcgaatct aaaatcggat aatatgacac gcgaagagtt tcagaacgac
     9601 attcgcgcgg gtattcccga ccggctgccc gccgcgaaac cctatgacaa acggatcaac
     9661 catgcgccca aacgcaagga catcctttcg gacgaggaga aggcgctggc cctgaaaaac
     9721 gccctgcgct attttccggt caggcaccac gccgtgctgg cgaaggagtt cgccgaggaa
     9781 ctgcgccgct acggccgtat ctatatgtac cgcctgcgtc ccgactacga gatgcacgcg
     9841 cgtccgatcg gcgaatatcc cgcccgctgc cggcaggcgg cggccatcat gctgatgatt
     9901 cagaacaacc tcgacccgcg ggtcgcccag catccccacg agctgatcac ctacggcggc
     9961 aacggcgccg tgttccagaa ctgggcgcag taccgccttg cgatgcagta tctttcggaa
    10021 atgactgaaa atcaaacctt ggtcatgtat tccgggcatc cgctggggct gttcccgtcg
    10081 catcccgacg ccccgcgcgt ggtggttacg aacggcatgg tgattcccaa ctactcgaag
    10141 cccgacgact gggagcggct caacgccctc ggggtgtcgc agtacgggca gatgaccgcc
    10201 gggtcgtaca tgtatatcgg gccgcagggc atcgttcacg gcacgacgat cacggtgatg
    10261 aacgccgcgc gcaaacgctt cacggccggc tgcaccgata cgcgcgggat gctgttcgtc
    10321 tcgtcgggtc tcggcggcat gtcgggagcg cagcccaagg cgggcaatat ttcgggcgtg
    10381 gtgtcggtcg tcgccgagat caaccccaag gcggcgcaga aacgccacga gcagggatgg
    10441 gtcgacgagc tgcatgaagc gctggatgag ctgatcccgc gtatccgcca ggctgtcaag
    10501 gcgaaagagg tcgtgtcgat ggcctatgtg ggcaacgtcg tggacctctg ggagcggctg
    10561 gccgcggagg agattccggt agacctgggt tcggaccaga cctcgctgca caacccctgg
    10621 gcgggcggtt actatcccgt ggggttgagc tacgaggcgt cgaacaagat gatggctgaa
    10681 gagccgggcc gcttccgcga atgcgtgcag gagtcgctgc ggcggcaggt cgacgccatc
    10741 aacaaattga ccgacagggg aatgtatttc ttcgactacg gaaatgcctt cctgctggaa
    10801 gcctcgcgcg ccggggccgc ggtgacgggc gagggcggac gcttccgcta cccctcctac
    10861 gtgcaggaca ttatgggacc catgttcttc gactacggct tcgggccgtt ccgctgggtc
    10921 tgcacctcgg ggaagcccga agacctcgaa acgaccgact ctctggccgc cgaagtgctg
    10981 gaggagatcc ggaagacggc tcccgacgac atccgggggc agctggacga caatatccac
    11041 tggattcgcg aggccgggcg caaccggctg gtcgtcgggt cgcaggcgcg cattctctat
    11101 gccgactgcg aagggcgcgt gaagatcgcc gaggcgttca accgggccat cgccgagggc
    11161 cgtatcacgg cccccgtggt gctggggcgc gaccatcacg acgtttcggg aaccgattcg
    11221 ccctaccgcg agacctcgaa catctacgac ggttcgtgcc tgacggccga catggccgtg
    11281 cagaacgtca tcggcgatgc gttccgcggc gcgacgtggg tttcgatcca caacggcggc
    11341 ggcgtgggct ggggcgaggt gatcaacggc ggcttcggca tggtgatcga cggttcggag
    11401 gatgccggcc gccgcatccg cgaaatgctg ctgtgggacg tcaacaacgg catcgcccgc
    11461 cgcagctggg cgcgtaacga aggggccgtc gaagccatcc gccgcgaaat ggaccgcacg
    11521 cccggactgc gtgtgaccct gcctgttttt gccgacgagg aacttgtccg cgaggcgctg
    11581 aacgaacagg gcggcgcttc ggataaatta tgaatttcga attatgaatt ttgaattttg
    11641 aattttgaat tgtcatccat ggaacatcac catatcaccg cggagcacct ttcggtcggg
    11701 cgcgtccgcg aaatcctcga acggcggctg ccgctcgcgt tgagcgacga cgcccgggcg
    11761 cgcatcgtcc gctgccgcga gtacctcgac cgcaagatgg agaaccccga gcggccgatc
    11821 tacggcatca cgaccggttt cgggtcgctg tgctacattt cggtgggccg cgacgagctg
    11881 tcgcgcctgc aacagaacct cgtgatgtcg cacgcctgcg gaaccgggga gcgcgtgccc
    11941 tcggagatcg tgcggctgat tctgctgctc aagatacagt cgctcgccta cggccattcg
    12001 ggcgtgcagc tggcgacggt ggagcgtctc gtggagtttt tcaaccgcgg catcctgccc
    12061 gtcgtctatc agcagggttc gctgggcgct tcgggcgacc tcgcgccgct ggcacatatg
    12121 agcctgccgc tgctggggct gggcgaggtg gagtataagg gcgaggtgcg tccctcggcc
    12181 gaagtgcttg ccgaactggg gctggagccg atccggttgc agtcgaaaga gggccttgcg
    12241 ctgctgaacg gcacgcagtt tatgagcgcc tacggcgtct ggtcgctgat ccacgcccgg
    12301 cggctgagcg agtgggccga ccgcatcggg gcgttgtcgt tagacgcctt cgacggtcgt
    12361 atcgagcctt tctgcgacga ggtgcacctg atccgcgccc accgggggca gctcgccacg
    12421 gcccggaatg tccgcgggct gctcgaaggc agcgaactga tcgcccgccc caagcaccac
    12481 gtgcaggacc cctattcgtt ccgctgcatg ccgcaggttc acggagcctc gaaggacacg
    12541 atcgactatg tggagagcgt gctgactacg gaaatcaact ccacgacgga caatccgacg
    12601 gtcttccccg aggaggacat ggtcgtctcg gcgggcaatt tccacggcca gccgatcgct
    12661 ctggcgatgg atttcctggc gatcgccctg gccgagctgg gcaacatctc cgagcgtcgc
    12721 acctacaaac tgatctccgg ggcgcgcgaa ctgcccaaat tcctcgtggc gaaccccggg
    12781 ctgaacagcg gctttatgat tccgcagtat accgcggcgt cgatcgtgag ccagtccaag
    12841 gggctgtgca tgcccgcgtc ggtcgattcg atcccctcgt cgcaggggca ggaggaccat
    12901 gtgagcatgg gttccaacgc tgccacgaag ctctggcgcg tggtctgcaa caccgaacgg
    12961 gtgctggcca tcgagctgtt caacgccgcg caggccatcg agttccgccg tccggcgcac
    13021 acgtcgcccg agttggagcg aatgctggcc gactatcgca aagaggttcc cttcatcgac
    13081 aacgacgagg tgatgtat
//
