LOCUS       c00023_gnlPro..        23249 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MKIECKOO_23.
ACCESSION   c00023_gnlPro..
VERSION     c00023_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 23:30:10
            Original ID  :: gnl|Prokka|MKIECKOO_23
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 21404
            Orig. end    :: 44653
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23249
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[31404:34653]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13249
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
     cand_cluster    1..23249
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /kind="single"
                     /product="Putrescine2spermidine"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..23249
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Putrescine2spermidine"
                     /region_number="1"
                     /rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /tool="gutsmash"
     CDS             1481..2938
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FGGY_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FGGY_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg23_20"
                     /sec_met_domain="FGGY_C (E-value: 3.3e-38, bitscore: 122.6,
                     seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="FGGY_N (E-value: 1.5e-80, bitscore: 261.4,
                     seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYYIGIDLGTSAVKLLLMEESGKICNIVSREYPLFFPHPGWSEQK
                     PEDWFAQSMEGMKELTKDIDRAQVAGIGFGGQMHGLVTLDKDDNVIRPAILWNDGRTGE
                     ETEYLNTVIGKDKLSQYTANIAFAGFTAPKILWMQKNEPENFKKVVKIMLPKDYLAYRL
                     SGSFCTDVSDASGMLLLDVKNRCWSKEMLEICGITEEQLPKLYESWEVVGTLKPEIAKE
                     LGFSENVKVVAGAGDNAAAAVGTGTVGDGQCNISLGTSGTVFISSKNFGVDENNALHSF
                     CHADGSYHLMGCMLSAASCNKWWAEEILQTKDFAAEQAPIQKLGENHVFFLPYLMGERS
                     PHNNPDARGVFFGMSMDSTRADMTQAVLEGVAFGLRDSLEVARSLGIKIERTKICGGGA
                     KSPLWKKIIANVMNLKVDVLENEEGPSMGGAMLAAVGCGAYPDVETIGKKFAKVVDTVE
                     PDPELVAKYEERYQKFRTLYPAMKPLF"
     CDS             complement(3049..3984)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     58; E-value: 2.3e-18)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg23_21"
                     /sec_met_domain="LysR_substrate (E-value: 1.1e-33,
                     bitscore: 107.5, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 1.3e-18, bitscore: 58.0,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFQGMEYIYEVYKEKSFSKAAAALFISQPSLSANVKRVENRIGYP
                     IFDRSTKPLQLTEVGKHYIQAVEKVMDIENNLENYLLDLGNLKTGTLNVGGSNFFSSWI
                     LPPLIADFSQKFPHVQISLVEESTAKLSQFLQAGKLDLVIDNCILDNQIFERYIYQKEQ
                     LLLAVPKNYSVNTRLQKYQIPIEEIRNGQFRSSHIPSVPLNKFENEPFIILRSDNDTGK
                     RALTICQENHFSPSVVFRLDQQMTAYNIACLGMGITFIGDLLLSRVPTNSELVFYKLPG
                     QSSKRTVFFYWKKGRYISRAMEEFLKLPFS"
     CDS             4100..5524
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lyase_1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FumaraseC_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg23_22"
                     /sec_met_domain="Lyase_1 (E-value: 3.5e-95, bitscore:
                     310.1, seeds: 17, tool: rule-based-clusters)"
                     /sec_met_domain="FumaraseC_C (E-value: 3.1e-22, bitscore:
                     70.1, seeds: 737, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKTDYRVERDSIGVKDIPEDVYYGVQSLRAAENFHITGLNMHPE
                     IINSLAYIKKAAAITNCEVGLLEKKKAQAIVQACDEIVSGKFHNEFIVDPVQGGAGTSL
                     NMNANEVIANRAIEILGGKKGDYTIINPNDDVNCGQSTNDVIPTAGKMTSLRLLQNLKK
                     QLLRLYDALNEKATEFDHIIKMGRTQMQDAVPIRLGQEFKAYSVAIMRDIHRMDKAMDE
                     MRTLNMGGTAIGTGINADEGYLRRIVPNLTEISGMDFIQAFDLIDSTQNLDSFVAVSGA
                     VKACAVTLSKMSNDLRLMSSGPRTGFGEINLPAKQNGSSIMPGKVNPVIPEVVNQVAFN
                     IIGNDVTITMAAEAGQLELNAFEPIIFYCMFQSIDTLGYAVQTLVDNCIVGITANEERC
                     RYLVENSVGIITAISPHLGYQKAADIAKKAIKTGESVRSLILKEKLMDEDELNRILDPI
                     HMTEPGISGKDYLIKK"
     CDS             complement(5633..7318)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FTHFS"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg23_23"
                     /sec_met_domain="FTHFS (E-value: 1.5e-275, bitscore: 905.7,
                     seeds: 408, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGFKSDIEIAQECEMLPITQIAEKAGIDDKYLEQYGKYKAKIDYN
                     LLKESDKKDGKLILVTAINPTPAGEGKTTTTVGLADGMQRLGKSVMVALREPSLGPVFG
                     VKGGAAGGGYAQVVPMEDINLHFTGDFHAIGAANNLLAAMIDNHIFQGNALNIDPRKIT
                     WRRCVDMNDRQLRNVVDGLGGKTNGMPREDGYDITVASEIMAVLCLASDIKDLKERLSK
                     IIIGYTYGKVSEQKPVTAGDLHAEGAMTALLKDALKPNLVQTLEHVPAIVHGGPFANIA
                     HGCNSVTATKMAMKLADYAITEAGFGADLGAEKFLDIKCRMAGLKPSAVVIVATVRALK
                     YNGGVAKADLNNENLEALEKGIPNLLKHVSNIKNVYKLPCVVAINAFPTDTKAELDFVE
                     AKCKELGVNVALSEVWAKGGEGGIKLAEEVIRLVEEPNDFSYAYELEGSIEDKLNQIVQ
                     KVYGGKKVVLTANAQKQAKQLEALGFGNCPICVAKTQYSLTDDQTKLGAPTDFEVTVRN
                     LKISAGAGFIVALTGEIMTMPGLPKVPAAERIDVDETGKITGLF"
     CDS             8541..9998
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_7_arginine"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg23_24"
                     /sec_met_domain="OKR_DC_1_C (E-value: 8.8e-14, bitscore:
                     43.2, seeds: 113, tool: rule-based-clusters)"
                     /sec_met_domain="OKR_DC_1_7_arginine (E-value: 1.9e-126,
                     bitscore: 413.0, seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDYERQQHAPIYEALERFRKKRVVPFDVPGHKRGRGNPELAQLLG
                     EKCVGLDVNSMKPLDNLCHPVSVIREAEELAADAFGAAHAFLMVGGTTSAVQSMILSVC
                     KAGDKIILPRNVHKSAINALVLCGAIPVYVNPEVNAQLGISLGMEVSQVEKAMDENPDA
                     VAVLVNNPTYYGICSDLRTIVKKAHARGMKVLADEAHGTHLYFGRNLPVSGMAAGADMA
                     AVSMHKSGGSLTQSSLLLLNKSMNAEKVRQIINLTQTTSASYLLLSSLDISRRNLALRG
                     EESFEKVAGMAQYAREEINEIGGYYAYGMDLINGTSVFDFDVTKLSIYTLGNGLAGIEV
                     YDLLRDEYDIQIEFGDICNILAYISIGDRLQDIERLVGALADIERLYKKDSTGMLSGEY
                     IAPAVVASPQQAFYAEKESLPMEQAAGRISGEFVMCYPPGIPILAPGEMVTQEIVEYIL
                     YARDKGCSMQGMEDPKVEHLQVLKGGI"
     CDS             10001..10861
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synth"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synt_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg23_25"
                     /sec_met_domain="Spermine_synth (E-value: 1.1e-53,
                     bitscore: 172.6, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Spermine_synt_N (E-value: 1.6e-15,
                     bitscore: 48.0, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELWYSEFHTGNVKLSVRINRQLFSGESEFQRIDVFESEEFGRFV
                     ALDGEIVFSDKDEFIYDEMVTHVPMTVHPNVKNVLIIGGGDGGVARELIHYPQIESIDV
                     VESDKMFVDVCAEMFPDIAQGLKDERVNIYYEDGLRFLRNKKARYDLIINDSTDPLGHT
                     EGLFTKEFYGSCYKALRDDGIMVYQHGSPFYDEDEVECRKMHRKVFRSFPVSRVYQAHI
                     PTCPSGYWLFGFASKKYHPLEDFRPERFDDLNIETWYYTTNLHRGAFMLPKYVEDLLEE
                     EENSL"
     CDS             10858..12138
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Sacchrp_dh_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Sacchrp_dh_NADP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg23_26"
                     /sec_met_domain="Sacchrp_dh_C (E-value: 1.3e-43, bitscore:
                     141.1, seeds: 375, tool: rule-based-clusters)"
                     /sec_met_domain="Sacchrp_dh_NADP (E-value: 7.8e-36,
                     bitscore: 114.4, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRLLVIGCGGVASVAIRKCCQNSDVFTEIMIASRTKEKCDALKE
                     KIESTTKTKIETAKVDADNAAEVAELIRAYKPDAVLNVALPYQDLTIMDACLEAGADYI
                     DTANYEAEDTEDPTWRAIYEKRCKEKGFTAYFDYSWQWAYDEKFKKAGLTALLGTGFDP
                     GVTSVFSAYALKHYFDEIHTIDILDCNGGDHGYPFATNFNPEINLREVSANGSYWEDGH
                     WVETEPMEFKSVYDFPEVGKKDMYLLHHEEIESLAKNIPGVQRIRFFMTFGQSYLTHMK
                     CLENVGMLSTAPVEFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGVKDGKEK
                     SIYIYNVCDHQECYKEVESQAISYTTGVPAMIGSMMVVTGQWKKPGVFNVEEFDPDPYM
                     EALNKWGLPWKVCEDPELVKVWKANED"
     CDS             12128..13249
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Orn_DAP_Arg_deC"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg23_27"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 6.8e-15,
                     bitscore: 46.4, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIDQLQTPCYVIDEKKMRENLEILKKVQENTGCKILLAQKAFSG
                     FALYPMIGKYLAGTTASGLFEARLGYEEMGKENHVFSPAYRTEDIEELDRICDHIIFNS
                     TAQLKKFKEVCTGASLGLRINPECSTQGDHAIYDPCAPGSRLGVTRENFDGECLKWIDG
                     LHFHTLCEQNADDLEKTLQAVEEKFGEFLSEVSWLNMGGGHHITREDYDVKLLEKCIQH
                     MKETYDLDIYLEPGEAVALNAGYLVTEVMDIVENEIRTLILDASAACHMPDVLEMPYRP
                     PLKDSGEAGEKAYTYRLSSCTCLAGDVIGDYSFDREIRIGDKLYFMDMAIYSMVKNNTF
                     NGMPLPDIAVMHEDGECEVIRHFGYEDFKSRLS"
     CDS             13284..14408
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PAD_porph"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg23_28"
                     /sec_met_domain="PAD_porph (E-value: 3e-128, bitscore:
                     418.7, seeds: 436, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEVTEKNRTKYRMPGEFEPHEGCVMIWPERPGSWNYGAREAQKAF
                     VKVAEAIGESENVYMLVSKAQMENAKNQLGNVSGVTLLECETDDAWARDVGATMVLDEK
                     GAVCGVDWQFNAWGGTFDGLYRNWEKDDRVAAFICRTLGCPCLDARPFVLEGGSIHSDG
                     EGTLIVTEACLLSQGRNPQMSREQIEEQLKYWLGVHKIIWLPCGIYQDETNEHVDNVCA
                     FVRPGEVVLAWTEDETDPQYAMSLADLKVLEQETDAKGRKFKIHKLPIPQKPVCLTQED
                     VDGFVFEEGEDEREAGERMAASYVNFYISNGGIILPQFGDENDKRAVEILQKCFPERRI
                     YPIDARAIIVGGGNIHCITQQIPGKISDLDAEKL"
     CDS             14489..15367
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CN_hydrolase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg23_29"
                     /sec_met_domain="CN_hydrolase (E-value: 1.3e-56, bitscore:
                     183.0, seeds: 52, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRNVTVAAVQMKCSKSVEKNIIHAEELVRQAAEKGADIVLLPELF
                     ERPYFCQERRYEYYEYAQTAEENPAVRHFSRVAAELGIVIPVSFYEKEVNNTYNSVAIL
                     DADGKNLGIYRKTHIPDDHYYQEKFYFTPGDTGFKVFDTRFGTIGVGICWDQWFPETAR
                     CMALQGAELLFYPTAIGSEPILECDSMEHWRRCMQGHAASNLIPVIAANRIGEETVEPC
                     PENGMQKSALNFYGSSFITDNTGALCAELPGGEEGVLVSTFDLDTLKADRLNWGLFRDR
                     RPEMYAKIVGK"
     CDS             15595..16056
                     /locus_tag="ctg23_30"
                     /transl_table=11
                     /translation="MNRKEFLEILRSQLAGQMQEGKAAAHIRYYEDYIQSQVRGGRSEQ
                     EVLQELGDPHLIAKTLIDTDDGSTQEDYGEYSSYGSSYGNETELPHQQEKRWKKVIDLS
                     TWHGRAVVIAAAAVIIVLLILIIGVAIPFFIILAIILYFLSWLKKRNDQ"
     CDS             16277..20992
                     /locus_tag="ctg23_31"
                     /transl_table=11
                     /translation="MKHNFKLKERLGALLLAMLFILQAILGLVPVCVTQAAPLTVETWD
                     SDKVVDYGYRFNMKFQPGITTYESFGCDNLDREAFSDNGKSERDTECVRVGADYKAGSA
                     GMRYNNVGKDGNGNIVDVRLILVGVENAEPRYDLRTAESIVQNKGGATFAWKDNEAYPM
                     VGFSKNSIGVFIYSVGYAKVKFQFLRHGTEETLPISGHGTIRDIDAGQGVRIPSDSSLD
                     NAYVLKNNDYLTVDGNSVSSPLGSVEPDDPRGWLNLFYNTDNFTVEFCHQFRLDKWDKS
                     REDAIAKAGSQERWAEITRNKYLDPSGNSYCPNFKGQKYCKAYAYFDFTSYCFGDVEMK
                     KAPEKRVGEANCTWEQAAAASKEKPFGIRQGQEFQYMIRAEVTPNRLKSFVVQDILEDC
                     LTIEDASKVSIVNDAGQTVTDWFDVAVEGQKVTCRAKAESLQDEAFTDNQTYTFTLKVR
                     QRPESEVNISKYLAEDGYSILVPNHASMSYERTNGSGDTMDTETVWVKGVIPPELEVKK
                     NTSQYEWKTGDIIDYEVLVSQTKQDVKAVNVVITDELPSCLQLLEGQYAVETSQGGENC
                     TLTGQGENGWKAECPSLKYGETITIRFKCQASADSNGQEWENIVTATADNLINPETGEQ
                     ESRKDMAEVWPNSPQLEIDKTADKYEWQAGEQVAYRIVVNNVTAGTIAKDVTITDIGLP
                     QGLVLAGGAQSMEVLGVQQQVNYPVPDKKTGQAYEARPVDSQLNADENGFSFYCSYVPY
                     SQPVTIIFHCIAQEEANGHESVNAATVKAANTDEQSDDAEVYVNSGEFWIEKSADHYEW
                     QVGEQVQYNVVVENKKVGTVARNVTVWDTGMPTGLALSSAEDVSVSGIPQNITQLTAGT
                     KDVLNQLNPEFYNETSEKPVNYEFLQEGSGWRLNISDLPANTPVMISFLCTVTEAANGM
                     ESINVANVQAQNAPVSQDDAEVYVNTAVLSIEKSFQNPYLAAGDGRAENEFRVGEQVNY
                     QVTVNNLQKGSIARNLVISDLSLPEGLALDGAEDAVTVSGVPAVIQNPVAGTDDAGNQL
                     NPENYKETVEKPVSCQVTRQGTGWIVTISDLPYQTPVTVNFRCTAQESINGMEIVNTAQ
                     AYADNAQKVKDSSKIWVNSPVLKVEKTTDKPFYKYGDIITYRIVLTQEQTGCVARNVTL
                     QDVIDTQGVRLLKDSVILMDEKGNVADADVQINDDNTFLMSTGRTLVRDSRYSICDNDK
                     GGLFEQVMYNPLDCQEQKSMIVEYQAAVIDAALAGQKVHNTAVADSSEKIPAIGETETE
                     VHSPILEIVKESDKKEYASGEKGYYKLTVRQLREDVTDQNIVIEDKLETQGASIVKDSI
                     FVKKNGIELKDAKIEADDTGFVIQTGASLSDMDKIEVCYEVVFKTESTEPEKIVNTAKA
                     RGDISPEITAQQEVYVKAKAEPTVTPTPSATPKPTETPKPTETPKPTEVPKPTEVPKPT
                     EQPKATPTPSVPGNCPKMTPVPTKAPLASYNGGNNGGTTSGSGGSSYGNSGGYGSYQGG
                     SMAGSSKTGDVRPFKMMAVLGLIGMGLLTGGVVIYRRTVSGKRNIKGMPRK"
     CDS             20989..21876
                     /locus_tag="ctg23_32"
                     /transl_table=11
                     /translation="MKKLRTFAVSMIIAAIGLLIYCAGFYIKSYEQNLAAKQEYAELSR
                     MAGMKNREDAGLLADGKKTDEDSSTKNSEKKRRKRQRRFSKSKNKNHADEIRESFGISW
                     ENLRKINSQTVAWITVPGADISYPVVQAADDEYYLKHNFRGEEDLFGCIFLEHDIKKNF
                     TDSHSILYGHNIEGNMMFANLNRYEQPEFLKKCPEIEITTPKRKFLYKIFSVEQASSQS
                     PAFEYGYKLSSPAYRRQLSILKNNSMYDTGVEPDERERMVTLITCNSRLDKEIRMAVHG
                     ICHECYGIEKAEPK"
     CDS             22068..23159
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1043:Periplasmic binding protein-like domain (Score:
                     107.3; E-value: 3.4e-33)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg23_33"
                     /sec_met_domain="Peripla_BP_3 (E-value: 1.9e-33, bitscore:
                     107.3, seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDNGKPKYFSLMEQLRSDIMSGAIRPGEKLPSENELSQKYSLSR
                     HTVRKALGILEQDGYVEAFHGRGTYCSENMRHIKNSKNIAVVTTYISDYIFPRLIQGMD
                     NVLSESGYSIILKNTANSRQKEARCLEELLKKDIDGLIIEPSKSEMICKHRNLYQNLDK
                     FEIPYVFIQGIYSEMRDKPHILMDDAQGGYLVTKYLLELGHKKIKGFFKADDMQGLERH
                     KGYVKALQESGIAYDPDDVVWFHTEDRKVKPALMAKEMVQSGQLPDGIVCYNDQIAVQV
                     MEELEKMGVRIPDDISITGYDNSLYAQRGSGITTIAHPQEKLGEMAAELILEKINGVPE
                     EESKVERLIYPELIIRGSCRKIL"
ORIGIN
        1 aggcttatac aaagaaatat gatgcagcag acatttatga atgtccgatc tgtatcgtag
       61 agagcgagat ccatatggtt caggctcttg aagatatcaa gaaagcggga tgtaatgcac
      121 tttgtgtata tcttggaaac ttcggaccgg aaatttccga aacacttctt gcaaagcatt
      181 tcgaaggacc gaagatgttc tgtgcagcag cagaagaaac acaggataat ctgatccagg
      241 gacgtggaga tgcatactgc ggtatgttaa atgcaagcta taacttacag cttcgcaatg
      301 taaaagcata tattccggaa tacccggttg gtgacgcaga agactgcgca gatatgatcc
      361 atgatttcct tccgatcgca agagcagtag aaggactcag caacttaaag atcatcagct
      421 tcggacctcg tcctacaaac ttccttgctt gtaatgcacc gatcaaacag ctttacaacc
      481 ttggagttga gattgaagag aattccgaac ttgacctgtt tgaagcattc aacaaacatg
      541 ctggagatga gagaatccct gcaattgtta aagaaatgga agaggaactg ggtgcaggaa
      601 acaagaaacc tgagattctt gcaaaacttg ctcagtatga actgactctg aaagactggg
      661 tagaggctca cagaggatat cgtaaatatg taacattaac aggaaaatgc tggcctgcat
      721 tccagacaca gtttggattt gttccttgct acgtaaacag ccgtctgact gctcagggca
      781 ttccggtatc ttgcgaagtt gatatttatg gtacattaag tgagttcatt ggaactgttg
      841 taagccagga tacagttaca ctgcttgaca tcaacaactc tgtaccgaag gatatgtaca
      901 aagagtctat tgagggcaaa tttgattaca cactgaaaga tacatttatg ggattccact
      961 gcggaaatac agcttccagc aagctttctt tctgtgagat gaagtatcag atgatcatgg
     1021 caagatctct tccgatagaa gttacaaacg gaactcttga aggagatatt gttcctggag
     1081 atatcacttt ctatcgtctg cagagcactg ctgataacaa actccgcgga tatattgcac
     1141 acggtgaagt tcttccggtt gcaacaaaat ctttcggtgc gatcggcgta tttgcaattc
     1201 ctgaaatggg acgtttctac cgtcatgtac tgattgaggg aggatatcca catcacggag
     1261 cagttgcatt cggacattat ggaaaagctt tgtttgaagt attcaaatac atcggtgttc
     1321 cggttgaaga aatcggatac aaccagccgg caggtgtaag atacccgaca gaaaatccat
     1381 ggggttaatt cagataaaca gactgacact ataaatttta atacatcccg ggggtttacc
     1441 ctgggatgta ttagattaga aatagaaaag gagagcactt atgtattata tcggtattga
     1501 tcttggtact tccgctgtaa aacttcttct tatggaagaa tcaggaaaaa tctgtaacat
     1561 cgtatccaga gaatatcctt tattctttcc acatccgggc tggtctgagc agaaaccgga
     1621 ggactggttt gcgcagagta tggaaggcat gaaagagctg acaaaggata tcgacagagc
     1681 gcaggtagca ggaattggtt ttggcggcca gatgcatggt ctggtaacac ttgacaagga
     1741 tgataatgtg atccgtcctg caatcctctg gaatgacgga cgtacaggcg aagagacaga
     1801 atatctgaat acagtgatcg gaaaagacaa actttcacag tatacagcaa atattgcttt
     1861 cgcaggcttc acagcaccga agatcctctg gatgcagaaa aatgagcctg agaactttaa
     1921 gaaggtagta aagattatgc ttcctaagga ttatctggca tatcgtctgt ccggttcttt
     1981 ttgtacagat gtttctgatg cttccggtat gcttcttctt gatgtgaaga accgctgctg
     2041 gtcaaaagaa atgctggaga tctgtggaat cacagaagag cagcttccga aactgtatga
     2101 gagttgggaa gtagtaggaa ctctgaaacc tgagattgcg aaagaacttg gattcagtga
     2161 gaatgtaaaa gttgttgcag gtgcaggtga caatgcggca gctgctgtag gaacaggtac
     2221 agttggtgac ggtcagtgta atatttccct tggaacatcc ggaactgtgt ttatttccag
     2281 taaaaacttt ggtgtggacg aaaataacgc acttcattct ttctgtcatg cagatggaag
     2341 ctatcatctg atgggatgca tgctcagcgc agcttcctgt aacaaatggt gggcagagga
     2401 gattcttcag acaaaggatt tcgcagcaga gcaggctcca attcagaagc tgggagagaa
     2461 tcatgtattc ttccttccat atttgatggg agagcgctca cctcataata atcctgatgc
     2521 aagaggtgta ttcttcggaa tgtccatgga cagcacaaga gcagacatga cacaggctgt
     2581 tctggaaggt gttgcctttg gtcttcgtga ttccctggaa gttgcaagaa gccttggaat
     2641 caagattgag agaaccaaga tttgcggtgg cggagctaag agcccactgt ggaagaagat
     2701 cattgcaaac gttatgaacc tgaaggttga tgttctggag aacgaagaag gaccgtccat
     2761 gggtggagct atgctggcag cagtaggctg tggtgcttac ccggatgtag aaaccatcgg
     2821 taagaaattt gccaaagttg ttgatacagt agaaccggat cctgaactgg ttgcaaaata
     2881 tgaagagaga tatcagaagt tcagaactct gtatccggcg atgaagccat tgttctaatc
     2941 gaatatctgc ctgacatact ggggttgttg tgcttattta gcacaacaac cccattttga
     3001 cgtacatctg atgatgacca atcaccatag cctattgatt atgacatatc aggaaaaggg
     3061 cagcttcagg aattcttcca tggctctgct gatatagcgg cctttcttcc agtaaaaaaa
     3121 cacagtgcgt ttactgctct gaccgggcag cttataaaaa acaagttctg aatttgttgg
     3181 aactctggag agcagaagat ccccgatgaa agtgataccc attcccaaac atgcaatatt
     3241 ataggcagtc atctgctgat ccaggcgaaa tactacagaa ggcgaaaagt gattttcctg
     3301 acaaatggta agtgcacgct taccggtatc attatctgaa cgaagaataa taaatggttc
     3361 gttctcgaat ttgtttaatg gaacagaagg aatatgagaa gaacggaact gcccgttccg
     3421 gatttcctca ataggaatct gatatttctg cagtctggta tttactgaat aatttttggg
     3481 aactgcaaga agaagttgtt ctttctggta gatataacgt tcaaaaatct ggttatccag
     3541 aatacagtta tcaatcacca gatctaactt tccggcctgg agaaactggg atagctttgc
     3601 tgtactttct tctacaagag aaatttgaac atgggggaat ttttgggaaa aatcagcaat
     3661 aaggggaggc agaatccacg aagaaaaaaa gttactgcca cctacattaa gagttcctgt
     3721 tttgagattt cccagatcca gtaggtagtt ttcgagatta ttttcaatat ccatgacttt
     3781 ttcaacagcc tgtatataat gttttccgac ttcagttaac tgtaaaggtt tggtacttcg
     3841 atcaaaaata ggataaccaa tgcggttttc cacacgtttt acattggcgc ttaaagaagg
     3901 ctgcgaaatg aaaagagcag cagcagcttt ggaaaagctt ttttccttgt agacctcata
     3961 gatgtattcc attccctgaa acatacaaac tcctccgata tataatttaa acactatata
     4021 ttttataaaa atatatgtat ttgattatat tatagcagag atatataatg agggcaaata
     4081 catgggaggg cgaataacta tgaaaaaaac agactatcgt gtagaaaggg attctattgg
     4141 tgtaaaggat attccggaag atgtatatta tggagtacaa tccttacgtg cggctgaaaa
     4201 tttccacatt acggggctga atatgcatcc ggaaattatt aacagtcttg catacataaa
     4261 aaaagcagca gcgataacca attgtgaggt ggggcttctt gagaagaaaa aagcacaggc
     4321 gattgtccag gcatgtgatg aaattgtttc aggaaaattc cataatgaat ttattgtgga
     4381 tcctgttcag ggaggagctg gcacatcttt aaatatgaat gccaatgaag taattgcaaa
     4441 tcgcgcgatt gagatactgg gaggaaaaaa gggcgattat acaattataa atcctaacga
     4501 tgatgtgaat tgtggacagt ctaccaatga cgttattcct actgccggta aaatgacttc
     4561 tcttcgtttg ttgcagaatc tgaaaaaaca gcttcttcgc ctctatgatg ctcttaatga
     4621 aaaagctaca gagtttgatc acataataaa aatggggcgt acacagatgc aggatgcagt
     4681 accaattcgt ctgggacagg aatttaaggc atattcggta gcaatcatgc gtgatatcca
     4741 cagaatggat aaagcaatgg atgaaatgcg gactcttaat atgggaggta ctgctattgg
     4801 aacaggaatt aatgcagatg agggctatct gagaagaatt gttccaaatc tcactgaaat
     4861 atcgggaatg gactttatac aggcttttga tctgattgat tccactcaga atctggattc
     4921 atttgtagcc gtttccggtg ctgtgaaagc atgtgcggta actctttcca aaatgtcaaa
     4981 tgatctccgt ctgatgtcct ccggtccacg tactggtttt ggggagatta atcttccggc
     5041 aaaacagaat ggttcctcta ttatgccagg taaagttaat ccggttattc ctgaagtagt
     5101 gaatcaggtt gcttttaata ttattggtaa tgatgttacc attaccatgg ctgcagaggc
     5161 tggtcagctg gaattaaatg cgtttgagcc gattattttc tattgcatgt ttcagtctat
     5221 cgatactctt ggctatgcag tccagacatt ggtagataat tgtattgtag gaattacggc
     5281 aaatgaagaa agatgccgtt atctggtaga aaacagtgta ggtattatca ctgcaatcag
     5341 cccccatctt ggatatcaga aggctgcgga tattgcaaaa aaggcaatta agacaggcga
     5401 atctgtaaga agtctgattc tgaaagaaaa gcttatggac gaggatgaac ttaatcgcat
     5461 tctggatccg atccatatga cggaacctgg tatttccgga aaagattatc ttataaaaaa
     5521 ataaagaaaa aaacaggcgg gaaaatcttc ccgcctgtaa aatcgtctgg acacatatca
     5581 tatataaata tgatttttat atttttgaat tattcgattg atctcaaccg gattagaaca
     5641 gacctgtaat cttacctgtc tcgtctacgt cgattctctc agcagccgga actttaggaa
     5701 gacctggcat tgtcatgatc tcgcctgtaa gagctacgat gaatcctgca ccagcggaaa
     5761 tcttcaggtt acgtactgta acttcgaagt cagtaggagc acccagttta gtctggtcat
     5821 ctgttaagct gtactgtgtc ttagctacac agatcgggca gttgccaaag ccaagagctt
     5881 ctaactgttt cgcctgtttc tgagcgttag ctgtcagaac tactttctta ccgccatata
     5941 ctttctgaac gatctggttc agtttgtctt cgatagaacc ttccagttca tatgcatagg
     6001 agaagtcgtt tggttcttca acaagacgga taacttcttc tgcaagtttg attccgcctt
     6061 cgccgccttt tgcccatact tcagaaagag caacgttaac gcccagttct ttacatttag
     6121 cttctacaaa gtcaagctct gcttttgtat ctgtagggaa tgcgttgata gcaacaacac
     6181 atggaagttt gtatacgttt ttgatgttgg aaacgtgttt taacaggttc gggatacctt
     6241 tttcaagagc ttccaggttt tcattgttaa ggtcagcttt agcaacgccg ccgttgtatt
     6301 tcagggcacg tactgtagct acgattacaa ctgcgcttgg ttttaaacca gccatacggc
     6361 atttgatatc aaggaatttc tcagcaccaa ggtcagcacc gaaaccagct tctgtgattg
     6421 cataatcagc aagcttcata gccatctttg tagctgttac agagttacat ccatgagcga
     6481 tgtttgcgaa tggtccacca tgtacgattg caggaacgtg ttccagagtc tgtacaaggt
     6541 ttggtttcag agcatctttt aacagggctg tcatagcgcc ttctgcgtga aggtcacctg
     6601 ctgttacagg tttctgctcg gaaacttttc cgtatgtata tccgatgatg atcttggata
     6661 atctttcttt caggtctttg atgtcgcttg caagacagag aactgccatg atttcagatg
     6721 caactgtgat gtcgtatccg tcttcacgag gcataccgtt tgtctttccg ccaagaccat
     6781 ctactacgtt acgaagctga cggtcgttca tatctacaca tcttctccat gtgatcttac
     6841 gtgggtcgat gtttaatgca ttgccctgga agatgtggtt gtcgatcatg gctgcaagta
     6901 agttgttagc tgcgccgatt gcatggaagt cacctgtgaa gtgaaggttg atgtcttcca
     6961 tcggaacaac ctgtgcgtat ccgccgcctg ctgcaccacc ttttacaccg aataccggtc
     7021 ctaaggatgg ctcacgaaga gctaccataa cactcttgcc aagtctctgc ataccatctg
     7081 caagacctac agtagtagta gttttacctt ctcctgctgg agttgggttg atagctgtaa
     7141 cgaggattaa ttttccatcc ttcttatcac tttctttcag aagattgtag tcgatttttg
     7201 ctttgtattt tccgtactgc tccagatatt tgtcgtcaat acctgctttc tctgcgatct
     7261 gagtaattgg aagcatctcg cattcctgtg caatttcaat gtctgatttg aatcccataa
     7321 ttgtttttct cctttcgttt ccgcataaca tgaaaaactt ctgttgctgt tcactccgcg
     7381 atcagcaaca attattaatt gaaagaagta tcggccggtc tgtctgacat tcctgatttc
     7441 tgctccggaa attataaaaa aaggccagta tctgaatact tcaaatactg cccagacggt
     7501 cggctcccac aaacctccga ctccacgtgg tttgcactcc actctttccg tcagtactcg
     7561 aaggttcttt caattgatga atacaatata tcattttgag aaaaaaatgt caagaaattt
     7621 ttgttgaaac gtcaaaaaat gtgagtaaac tggataaaag ttgtgcaaat tgataagaga
     7681 agagaatcgt aatccctggt aatgaaagaa aatacgtttt ctcaagggaa gaaattgtta
     7741 aaaaataaac atagtttttc ctgataaata agaaaatata aaaagcgggt aaagctagag
     7801 cgtgtctgaa aaatcattcc cgcaatctgc acgccccact ttgcgggata tttcacccga
     7861 attcagttgc cgtagcccgc tacggcgccc tcatccgggc aaaatatacc acaaattgtg
     7921 acgcacatct tgcagaaagc ctttttcaga cacgctctag tgcaaaatat ggaaaatgga
     7981 attgacaaca gttcagaaga tatgttattc tcatctttag tatgaaaaga cactatcgtt
     8041 ttcatgcaaa tatttgctca cattcagaga cagtttctga atgttaagcc atacggacag
     8101 gcggggcagt tgccgggtgg gagacaccac attattgatt gagttagaag ctcaaatttt
     8161 ataagttgat tactttataa taatcagtgc gtaagcacac atcatcttgt gaaacggtca
     8221 ataagagcat agcatatatt tgccagcgat tgaagacgac agcagtcatg aatatttcag
     8281 aatacgggaa caggcacagg atacagacgg atttatacgg gaaatccggt cagtatataa
     8341 agagacagag cctgagaaat tctatagatc atgagagaag cagatggtga atgaacttat
     8401 ctgcttcttt ttttgtgcag atatagcaaa tatatagaga aataattgaa tcattgtgcc
     8461 ggtttgaggc agtatacaat tgctgaatga tagaactgta tttgccggta catgacgaca
     8521 ggaaaagagg aacatgtcaa atggattatg aaagacaaca gcatgcgccc atatatgaag
     8581 cactggaacg tttccgaaag aagagagtgg ttccctttga tgtgccggga cataaaagag
     8641 gaagaggaaa tccggagctt gcacagttgc tgggagagaa atgtgtgggg ctggatgtta
     8701 attctatgaa gccgctggac aatctctgcc acccggtttc ggtgatcaga gaagcggagg
     8761 aacttgcagc agatgctttt ggcgcagcgc atgcatttct tatggtagga ggaaccacat
     8821 ctgcagtgca gagtatgatt ctttctgtct gtaaggcagg ggacaagatc attctgccgc
     8881 gaaatgtaca taaaagtgcc atcaatgctc tggtactgtg tggtgcaatt ccggtttatg
     8941 taaacccgga ggtgaatgcg cagctgggta tctcccttgg catggaggtc agccaggtgg
     9001 agaaggctat ggatgagaac ccggatgcgg tggcggttct tgtaaataac cctacctatt
     9061 atggaatctg ttcggatctg cgaactatcg taaagaaggc tcatgccaga ggaatgaagg
     9121 tgctggcaga tgaggctcat ggaacccatc tttatttcgg cagaaacctt cccgtatccg
     9181 gaatggcggc aggtgccgac atggcggcag tttccatgca caaatccggc ggaagtctga
     9241 cacagagttc gctgctgctt ttgaataaga gtatgaatgc agagaaagtg cgccagatca
     9301 tcaatctgac tcagaccaca agtgcttctt atcttctgtt gtccagtctg gatatctcca
     9361 gaagaaatct ggcactcagg ggagaggaat cctttgaaaa ggttgcaggg atggcgcagt
     9421 atgccagaga ggagatcaat gagatcggcg gttattatgc atatggtatg gatctgatca
     9481 acggaaccag tgtttttgat tttgatgtta caaaactctc catttataca ctgggaaatg
     9541 ggttggcagg tattgaagtt tatgatcttc tcagagatga atatgatatt cagatcgagt
     9601 ttggagatat ctgtaatatt ctggcttaca tttccatcgg agacaggctt caggatattg
     9661 agagactggt aggggcattg gctgatattg aacgtctgta taagaaggac agcacaggta
     9721 tgctttccgg ggaatatatc gcacctgcag tggtggcgtc tccacagcag gcattttatg
     9781 cggagaaaga atctctgccc atggaacagg cggcaggcag gatcagcggt gaatttgtta
     9841 tgtgttatcc tccgggaatc ccgattcttg ctcctggaga aatggtgaca caggaaattg
     9901 tagaatacat tctttatgca agagacaaag gctgttccat gcagggaatg gaggatccga
     9961 aggtagaaca tcttcaggtc ctgaaagggg gtatctgatc atggaattat ggtattccga
    10021 gttccataca ggaaatgtaa agctttctgt ccggattaac cgacagttat tttcagggga
    10081 aagtgaattt cagagaatcg atgtgtttga gtctgaagaa tttggaagat ttgtggctct
    10141 ggacggtgag atcgtattct ctgataaaga tgaatttatt tatgatgaaa tggtcacgca
    10201 tgtgccaatg acagtacatc ccaatgtaaa aaatgttctg atcatcggcg gcggtgacgg
    10261 tggagttgcc agagaactga tccattatcc acagattgag agcattgatg tggtggaatc
    10321 agataaaatg tttgtggatg tatgtgcgga gatgtttccg gatattgccc agggactgaa
    10381 ggatgagaga gtcaacattt attatgaaga cggccttcgg ttcctgcgga ataaaaaggc
    10441 cagatatgac ctgatcatca atgattccac agatccgctg ggacatacag agggactttt
    10501 tacaaaggaa ttctacggaa gctgttataa ggctctcaga gatgacggaa tcatggttta
    10561 tcagcatgga agtccttttt atgatgagga tgaggtggaa tgcagaaaga tgcacagaaa
    10621 ggttttccgg tcatttccgg tgagcagggt ttatcaggca catatcccta cctgtccttc
    10681 gggatactgg ctttttggat ttgcatcaaa gaaatatcat ccactggaag atttcaggcc
    10741 ggagaggttt gatgatctta atatagaaac atggtattat acaacaaacc ttcacagagg
    10801 agcatttatg cttccaaaat atgtagaaga tttactggaa gaggaggaaa acagtttatg
    10861 agcagattat tggtaatcgg atgtggcggg gtagcttcag tggcaatccg caaatgttgt
    10921 cagaacagcg atgtttttac agagattatg atcgcaagca ggacaaagga aaaatgcgat
    10981 gcactcaaag agaagattga aagtacaacg aagacaaaaa ttgagacagc aaaggtagat
    11041 gcggataatg cagcagaggt cgcagaattg atcagagcct ataagccgga tgctgtcctg
    11101 aatgtggcac ttccatatca ggatcttacc atcatggatg catgtctgga agccggtgcg
    11161 gattatattg atactgccaa ttatgaagca gaggatacag aagatcccac atggcgtgca
    11221 atctatgaaa agagatgtaa agaaaaaggc tttactgcat atttcgatta ttcctggcag
    11281 tgggcttatg atgagaaatt taagaaagca ggactgactg ctcttctggg aaccggtttt
    11341 gatccgggtg ttaccagtgt attcagtgct tatgccctga agcattattt tgatgaaatc
    11401 cataccattg atattctgga ctgtaacggc ggtgatcatg gatatccttt tgccacaaac
    11461 tttaacccgg agatcaatct tcgagaggtt tccgcaaatg gttcctactg ggaagacgga
    11521 cattgggtag aaacagagcc tatggaattt aaatctgtct acgattttcc tgaggtagga
    11581 aagaaggata tgtatcttct tcatcatgaa gagattgaat cactggcaaa gaatattccg
    11641 ggagtacaga ggatccgttt ctttatgaca ttcggacaga gctatctgac acatatgaaa
    11701 tgtctggaaa atgtaggaat gctttccacc gcacctgtgg aatttaacgg acaggagatc
    11761 gtgccgatcc agtttttgaa agctcttctg ccggatcctg catctctggg tccgagaaca
    11821 gtgggtaaaa caaatatcgg ctgtattttc acaggtgtta aggacggaaa agagaaaagt
    11881 atttatattt ataatgtatg tgatcatcag gaatgctata aagaggtgga atcccaggca
    11941 atctcctata caacaggtgt tccggctatg atcggttcca tgatggtagt gaccggacag
    12001 tggaagaagc cgggtgtatt taatgtggaa gaatttgatc cggatccata tatggaagca
    12061 ctgaacaaat ggggacttcc atggaaagtc tgcgaagatc ctgaactggt aaaggtctgg
    12121 aaagccaatg aagattgatc aactgcaaac tccctgctat gtgatcgatg agaagaagat
    12181 gcgggagaat ctggagattt tgaaaaaagt ccaggagaat accgggtgta agatccttct
    12241 ggcacagaaa gcgttttccg gctttgctct gtatcccatg atcggaaaat atctggcagg
    12301 taccactgcc agcggtctgt ttgaggcaag gcttggatat gaagagatgg ggaaagagaa
    12361 tcatgttttt tcccctgctt accgtacaga agatatagag gaactggatc gtatctgtga
    12421 ccatattatc tttaattcca cagcacagct gaagaaattt aaagaagtgt gtaccggagc
    12481 cagtctggga ctccgtatta atccggaatg ctccactcag ggggatcatg cgatctatga
    12541 tccctgtgcg ccgggttcca ggctgggggt taccagagag aactttgacg gggaatgtct
    12601 gaaatggatc gacggactgc attttcatac gctctgcgaa cagaatgcgg atgacctgga
    12661 gaaaacattg caggcggtag aggagaagtt tggagaattt ctgtctgagg tttcctggct
    12721 gaatatgggc ggcggacatc atattaccag agaggattat gatgtaaagc tcctagaaaa
    12781 atgtattcag catatgaagg aaacctatga tctggatatt tatctggagc ccggggaggc
    12841 tgttgccctg aatgccggat atctggtgac agaggttatg gacattgtgg aaaatgagat
    12901 cagaacgctg attctggatg cttctgcagc ctgccatatg ccggatgtgc tggagatgcc
    12961 ctatcgtccg cctcttaagg acagcgggga agcaggggag aaggcatata cctaccgctt
    13021 atcttcctgc acctgcctgg caggagatgt gatcggagat tattcctttg acagagagat
    13081 ccggatcggg gacaagctgt attttatgga tatggcgatt tattctatgg tgaagaataa
    13141 tacatttaac ggtatgccgc tgccggatat tgcggttatg catgaggacg gagagtgtga
    13201 ggttatcaga catttcggat acgaagactt taaaagccgg ctttcctgat atctgccggg
    13261 ctatcaaaga aaaggagaca gacatggaag ttacagagaa gaacagaaca aaatatcgta
    13321 tgcccggaga atttgagcct catgagggat gtgtgatgat ctggccggaa cgtcccggtt
    13381 cctggaatta tggggcaagg gaagcgcaga aagcatttgt gaaagttgca gaggctattg
    13441 gagagagcga aaatgtatat atgctggttt ccaaagctca gatggagaat gcaaagaatc
    13501 agcttggaaa tgtttccggt gtgactttgc tggaatgcga gacagatgat gcctgggcga
    13561 gagatgtggg agcaaccatg gttctggatg agaaaggggc ggtctgtgga gttgactggc
    13621 agtttaatgc ctggggaggt acctttgacg ggctttaccg gaactgggaa aaggacgaca
    13681 gggtggctgc ctttatctgc aggactcttg gttgtccatg tctggatgcc agaccttttg
    13741 tgctggaggg cggttccatc cattctgacg gagaggggac tctgatcgtt acagaggcct
    13801 gtcttctgag tcagggacgc aatcctcaga tgagcaggga acagatagag gaacagttga
    13861 agtactggct cggtgtccac aagattatct ggcttccatg tggaatctat caggatgaaa
    13921 ccaatgagca tgtggataac gtgtgcgctt ttgtaaggcc cggagaggtt gtgcttgcat
    13981 ggacagagga tgagacagat ccgcagtatg ccatgtcttt ggctgatctg aaggtgctgg
    14041 aacaggaaac agatgcaaaa ggcagaaaat ttaagattca taagcttccg attcctcaga
    14101 aaccggtctg ccttacccag gaagatgtgg atggctttgt gtttgaagag ggagaagacg
    14161 aacgggaagc aggagaacgg atggctgcca gttacgtgaa tttctatatt tccaatggag
    14221 ggatcatcct tccacaattt ggggatgaaa atgacaaaag ggcagtggag attctgcaga
    14281 agtgttttcc tgaaagaagg atttatccca ttgatgccag agccatcatt gttggcggtg
    14341 gaaatattca ctgtatcacc cagcagattc ccggaaaaat atctgacctt gatgcagaaa
    14401 aactttgaga gtcatgtgtt tgagggttat tacctgaaag ttatgaaaaa acttacttat
    14461 gtaaacagga gcaggaggaa cagacaggat gagaaatgta acagtggcag cagttcagat
    14521 gaaatgcagt aaaagtgtgg agaaaaatat tatccatgca gaggaactgg tgcgtcaggc
    14581 agcagaaaag ggagctgaca ttgttcttct gccggagctt tttgaacggc cctatttctg
    14641 tcaggagcgc agatacgagt attatgaata tgcgcagact gcagaggaaa accctgctgt
    14701 gcgtcatttc agcagggtag cggcagagct ggggattgtg attccggtca gcttttatga
    14761 aaaagaggtc aataatactt ataacagcgt tgcgattctg gatgcagatg ggaagaatct
    14821 cggcatttac cggaaaacac atattccgga tgaccattat tatcaggaaa aattctattt
    14881 cacaccggga gataccggct ttaaggtttt tgataccaga tttggaacca ttggagttgg
    14941 aatctgctgg gatcagtggt tcccggaaac ggcaagatgt atggcactgc agggcgcaga
    15001 gcttcttttt tatcccactg ccatcggaag tgaacccatc ctggaatgtg acagcatgga
    15061 acactggaga agatgtatgc agggacacgc tgcctccaac ctgatccctg tgatcgctgc
    15121 caacagaatc ggtgaggaaa cagtagagcc atgtccggaa aacggaatgc agaaatctgc
    15181 tcttaatttt tacggctctt cttttatcac agacaacaca ggtgctctct gtgcagaact
    15241 gcccggaggg gaagaggggg tgcttgtaag cacttttgac ctggatacat taaaggcaga
    15301 cagactgaac tggggacttt tcagagaccg cagacctgaa atgtatgcaa aaattgtcgg
    15361 gaaatgacat acaagccaaa cttccattgc cgcaggcaat ctggaatgaa ttttggctca
    15421 gttactgaga acggagtgaa cagtaactga gtttataaga atttcataaa aagtttatga
    15481 ttatattagt tgctacctgc ggtatatatg gtaaaataag agtacgaacg ttactgataa
    15541 cggagagagc agtagagttt tgacatgtat ttctggcaaa atggagtgta gaagatgaac
    15601 agaaaagaat ttttggaaat cctgagaagc cagcttgccg gtcagatgca ggagggcaaa
    15661 gcagcggcac atatcaggta ttatgaagat tatatacagt ctcaggtacg tggcggacgt
    15721 tcagagcagg aagtactgca ggaactggga gacccgcatc tgatagcaaa aactctgatc
    15781 gatacagatg atggaagtac acaggaagat tacggagagt attcttctta cggaagcagt
    15841 tatggcaatg agacagagct tcctcatcag caggagaaac gatggaaaaa agtaatcgat
    15901 ctttctacct ggcatggcag ggctgttgtt attgcagcgg cggctgttat aattgtttta
    15961 ctgatactga taatcggagt tgcgattccg ttttttatta ttcttgcaat tattctttac
    16021 tttctttcat ggctgaagaa aagaaatgat caatgaaaat ctatgcaggg tttcagaaaa
    16081 gaaaccctgc gcaaaatctt aaaaatttta aaaatctaaa aaatcttaag tgtaagcgtt
    16141 cttgtttcac gatattaatt ccccttgaat atttataatc atacaatttc cacttatttc
    16201 tattctttaa tcctgccttg tgcagggaaa aatcccacat tcatttttat atttttgttc
    16261 ggaaaggaga cggaaaatga aacacaattt caaactgaaa gaacgccttg gagctttgct
    16321 gcttgcaatg ctttttattc tgcaggcaat tctggggctt gtgcctgtct gcgtaaccca
    16381 ggcggcaccg ttaactgtag aaacatggga cagtgataag gttgtagatt atggttatcg
    16441 ctttaacatg aagtttcagc ccggaattac aacatatgaa tcttttgggt gtgataatct
    16501 ggacagggaa gctttttcag acaatggaaa aagcgaacgt gacacagagt gcgttcgtgt
    16561 aggagcggac tataaagccg gaagcgcagg gatgcgttat aacaatgtag gaaaagatgg
    16621 aaatggaaat attgttgatg tcagactcat tcttgtggga gtagagaatg cagaaccccg
    16681 ttatgatctg cgcactgcag aatcgattgt tcagaataaa ggcggagcta cgtttgcatg
    16741 gaaagataat gaagcttatc caatggttgg cttttccaaa aacagtatcg gtgtatttat
    16801 ttattctgta ggatacgcaa aggttaagtt tcagtttctg aggcatggaa cagaagaaac
    16861 actgccgatc agtggccatg gaaccatacg tgatattgat gcgggacagg gagtccgtat
    16921 tccgtcagac agcagtctgg ataatgcata tgttctgaaa aacaatgatt atctgacggt
    16981 agatggaaat tctgtaagct cacctcttgg ttccgttgag ccggatgatc cgagaggatg
    17041 gctgaatctt ttttataata cggacaattt tacggtagag ttctgtcatc agttcaggtt
    17101 ggataaatgg gataaaagtc gtgaagatgc cattgccaaa gccggttctc aggaaagatg
    17161 ggcagagatt acaagaaata aatatctgga tccatcaggc aacagttatt gtccgaactt
    17221 taaaggacag aaatactgca aagcatatgc atattttgat tttacatcct attgtttcgg
    17281 tgatgttgaa atgaaaaaag cgcctgagaa acgtgtggga gaggcaaact gtacatggga
    17341 acaggcagct gccgcatcaa aagaaaaacc ttttggcatt cgtcagggac aggaatttca
    17401 gtatatgatc cgggcggagg tgacacccaa tagactgaaa tcctttgtgg tacaggatat
    17461 acttgaggat tgtcttacta tagaggatgc atcaaaagtc agtattgtga atgatgcagg
    17521 gcagacagtg acagactggt ttgatgttgc tgttgaagga cagaaagtga cctgcagggc
    17581 caaagcagag agccttcagg atgaagcatt tacagataat cagacttaca catttacttt
    17641 aaaagtacgc cagagaccgg aatcagaagt taacatttca aaataccttg cagaggatgg
    17701 atacagtatt cttgtaccaa accatgcatc catgagttat gaacgtacaa acggaagcgg
    17761 agatacaatg gatacggaaa cagtgtgggt aaagggtgtg attccaccgg aactggaagt
    17821 aaagaaaaat acttctcagt atgaatggaa aacgggagat atcatagatt atgaggttct
    17881 ggtttctcag acaaaacagg atgtaaaagc agtaaatgtt gttattacag acgagcttcc
    17941 atcatgtctg cagcttctgg aagggcagta tgctgtagag acaagtcagg gaggcgagaa
    18001 ctgtacgctt actggacagg gagaaaatgg atggaaagca gagtgtccgt ccctgaagta
    18061 tggggagacg atcacaatcc gttttaaatg tcaggcatct gcggattcca atggacagga
    18121 atgggaaaat attgtgactg caacagcgga taatctgatc aatcctgaga caggagaaca
    18181 ggaatccaga aaggatatgg cagaagtatg gccgaacagt ccacagcttg aaattgataa
    18241 aacagcagac aaatatgaat ggcaggcagg agagcaggta gcttaccgga tcgtggtgaa
    18301 taatgtaacg gcaggaacaa ttgcaaaaga tgtaactatt actgatattg gtctgccgca
    18361 gggactggtt ctggcaggtg gtgcacagag catggaagta ctgggagttc agcaacaggt
    18421 aaactatccc gtaccggata agaaaacagg acaggcatat gaagcgagac ctgtggattc
    18481 tcagttgaat gcagatgaga acggattttc cttttattgt tcttatgtgc catacagtca
    18541 gcctgtaacg attattttcc attgtatcgc acaggaagag gcaaatggac acgaaagcgt
    18601 aaatgcagca actgtaaaag ctgctaatac agatgagcaa tctgatgacg cagaagtata
    18661 tgtaaattca ggagaattct ggattgagaa atctgcagat cattatgaat ggcaggtcgg
    18721 agaacaggta cagtacaatg tggtggtgga gaataaaaaa gtaggtacag tggcccggaa
    18781 cgtaactgtc tgggataccg gtatgccgac aggacttgcg ctttcatcgg cagaggatgt
    18841 atcggtaagc ggaatcccac agaatattac gcagctgaca gcagggacca aagatgtttt
    18901 gaaccagctc aatccggaat tttataatga gacatcagag aaaccggtga attatgaatt
    18961 tcttcaggag ggaagcggat ggagactgaa catttcagat cttccggcaa atactccggt
    19021 tatgatttct ttcctttgca cagttacgga agcggcaaat ggaatggaaa gcattaatgt
    19081 tgccaatgtg caggcgcaga acgcccctgt ttcgcaggat gacgcagaag tgtatgtaaa
    19141 tacagcagtt ctttctattg agaaaagttt tcagaatcca tatctggcag ccggggacgg
    19201 acgtgcggaa aatgaatttc gggtagggga acaggtgaat tatcaggtta cggttaataa
    19261 tcttcagaag ggatctatcg caagaaatct tgtgatcagt gatctttccc ttcctgaagg
    19321 gctggctctg gacggagctg aagatgctgt tactgtaagc ggtgttccgg ctgttattca
    19381 gaatccggtg gcaggaactg atgatgcagg aaatcagctg aatccggaaa attataaaga
    19441 aacagtggaa aaaccggtca gctgtcaggt tacacgtcag ggaaccggat ggatcgtgac
    19501 gatttcagat cttccgtatc agacacctgt gactgttaat ttccgctgta ctgcgcagga
    19561 aagcataaat gggatggaga ttgtaaatac agcacaggca tatgcagata atgcacagaa
    19621 agtaaaggac tcctcaaaaa tctgggtgaa ctcgcctgtt cttaaagtag agaagacgac
    19681 agacaaacca ttttacaaat atggtgatat tattacatac cgcattgtcc tgacacagga
    19741 gcagaccgga tgtgtggcgc gtaatgttac tttgcaggat gtgatcgata ctcagggagt
    19801 acgtcttctg aaggattcgg tgattctgat ggatgagaaa ggaaatgtgg cagatgctga
    19861 tgtacagatc aatgatgata atactttcct gatgtcaaca ggcaggacac tggtcaggga
    19921 tagcagatat agtatctgcg ataatgataa aggcggtctt tttgagcagg taatgtataa
    19981 tcctctggac tgtcaggaac agaaaagtat gatcgtggaa tatcaggcag cggtgattga
    20041 tgcagccctg gcaggacaga aagtgcacaa tactgcagtt gcagacagca gtgaaaagat
    20101 acctgcaatc ggggaaacag agacagaggt acacagtccg attctggaaa ttgtgaagga
    20161 atcagataag aaagagtatg cgtccggtga gaaaggatac tataaactga cagtaagaca
    20221 actgcgtgag gatgtcacag atcagaatat tgttatcgaa gataaactgg aaacccaagg
    20281 ggcttccatt gtaaaagaca gcatttttgt gaagaaaaac ggtatagaac tgaaagatgc
    20341 caaaatagag gcagatgata caggatttgt aattcagaca ggagcatcgt tgtcagatat
    20401 ggataaaatt gaagtctgct atgaagtggt atttaaaaca gaaagcacag agcctgaaaa
    20461 aattgtaaac acagcgaaag caagaggtga tatttcaccg gaaattactg cgcagcagga
    20521 ggtatatgtg aaagcaaaag cagaacccac tgtcacacca acaccgtctg caacaccgaa
    20581 accaacagaa acaccaaagc cgacagagac accaaaacct acagaagtac cgaaacctac
    20641 agaagtaccg aaaccgacag agcagccaaa agccacacca acaccatctg taccgggaaa
    20701 ctgcccgaaa atgactcctg taccgacgaa agcaccgtta gcatcttaca atggtggaaa
    20761 taatggaggc acaacttccg gaagcggagg cagcagttat ggaaattcag gtggatacgg
    20821 aagctatcag ggtggttcca tggcaggaag ttctaaaaca ggagatgtca gaccgtttaa
    20881 aatgatggct gttcttggac ttatcggaat gggactgctg acaggaggtg tggtgatcta
    20941 cagaagaact gtttccggga aaagaaatat aaagggtatg ccgcggaaat gaaaaaactc
    21001 agaacatttg cagtaagtat gatcatagca gcaattgggc ttcttatata ttgtgccggt
    21061 ttctatataa aaagttatga acagaatctt gcagcaaagc aggaatatgc agagctttcc
    21121 cggatggcag ggatgaagaa cagagaagat gccggattat tggcagatgg caaaaaaact
    21181 gatgaagaca gcagtacaaa aaacagtgaa aaaaaacgca gaaaaagaca gagaagattt
    21241 tctaaatcaa aaaacaaaaa ccacgcagat gaaatcaggg aatccttcgg gatttcctgg
    21301 gaaaatttaa gaaagatcaa ctctcagaca gttgcctgga ttactgtccc gggagccgat
    21361 atttcttatc ctgtagttca ggcggcagat gatgaatatt acctgaaaca taatttcaga
    21421 ggagaggaag atctgtttgg atgtattttt ctggaacatg acataaaaaa gaattttaca
    21481 gattcccaca gtattcttta cgggcataat atagaaggta atatgatgtt cgcaaatctg
    21541 aaccgttatg aacagcctga atttctgaaa aaatgtcctg aaattgagat cacaacacca
    21601 aaaagaaagt ttctgtacaa aattttttct gtggaacagg catcttccca aagcccggca
    21661 tttgaatatg gatacaagtt atccagtcct gcatacagga gacaattatc tatattgaaa
    21721 aataattcca tgtatgacac aggagtagag cctgatgaaa gggagagaat ggtgactctg
    21781 atcacctgta attcacgtct ggataaagaa atacgtatgg cagtacatgg gatttgccat
    21841 gaatgttatg gtatagaaaa agctgagccg aagtgatgtt gaaatcaatc ggatattggt
    21901 aactttcgta aaggatgaac tgttactgtt cacacatcac tatccctcga ggtgtttcgg
    21961 aaaaaactaa tgaaaaatct ctcgatattt tgtataattt atgcataaaa aacaacttgt
    22021 tcgtacgtgc gtacaagttg tatcctaaat acaggaggga agaagacatg acagataatg
    22081 gaaagccgaa atatttctca ctgatggaac agctcagaag tgatattatg tcaggagcta
    22141 tccgaccggg agagaagctt ccttcagaaa acgagctttc acagaaatat tccctgagca
    22201 gacatacagt tcgtaaagca ctgggaatcc tggagcagga cggatatgta gaggcatttc
    22261 acggaagagg tacttattgc tctgagaata tgcgccatat aaagaattca aagaatattg
    22321 cggtagtgac cacatatatt tctgattata tttttccgag actgatacag ggaatggata
    22381 atgtcctttc agaaagcggt tacagtatta tcctgaaaaa cacagcaaac agcagacaga
    22441 aagaggccag atgtctggag gaacttctga agaaagatat tgatggactg atcattgaac
    22501 caagcaaaag tgagatgatc tgtaaacaca gaaatcttta tcagaatctg gataaatttg
    22561 aaattccgta tgtgtttatt cagggaatct attcagaaat gagggataaa cctcatattc
    22621 ttatggatga tgcacaggga ggctatcttg taacaaaata tctgctggaa ctgggacata
    22681 aaaagatcaa gggtttcttt aaggcagacg atatgcaggg actggagcgc cacaagggat
    22741 atgtgaaggc cttacaggag tcagggattg cctatgatcc tgatgatgtt gtctggtttc
    22801 atacagagga caggaaagta aaacctgcat tgatggcaaa agaaatggta cagagcggac
    22861 agcttccgga tggaatcgtc tgttacaatg atcagattgc tgttcaggtt atggaagaac
    22921 tggagaaaat gggagtcagg ataccggatg atatttccat taccggttat gacaattcac
    22981 tgtatgctca gcgaggaagc ggaatcacaa cgatagctca tccgcaggaa aagctgggag
    23041 aaatggcagc agagcttata cttgagaaga tcaacggagt tcctgaagaa gaaagtaagg
    23101 ttgaaagact gatttatccg gaactgatca tacggggatc atgcagaaaa atattgtaaa
    23161 caaatgaaat aaataaaaaa taaaaataaa tccaggagga attttatcat gaaaacagga
    23221 agaaactata agttttggtt ttgtacagg
//
