LOCUS       c00206_gnlPro..         7053 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BLHNNCLI_206.
ACCESSION   c00206_gnlPro..
VERSION     c00206_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 18:37:11
            Original ID  :: gnl|Prokka|BLHNNCLI_206
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 7053
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..7053
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2546:7053]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2547..7053
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..7053
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..7053
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             7..2418
                     /locus_tag="ctg206_1"
                     /transl_table=11
                     /translation="MKIRAIAALLFILISVSAFGEGRIKITGYVRDADGNPLELVNVRV
                     KNTLIGSMTNEKGYYSFSISPGDSISVIYSCLGYNKAERIIPSAQADMRLNVQMNNTSF
                     DLGEVSVTAIRKQTTTMESLNADKIKLLPDPSGGSIESLVVTFAGVSSNNELSSQYSVR
                     GGSYDENIVYVNGIEVFRPLLIRSGQQEGLSFINPDLTEAVNFAAGGFEARYGDKMSSV
                     LDITYKKPKIFEGSASASLLGANAYVGSSIGKFTQVTGFRFKSGRSILGTMDTDAEYDP
                     KFIDLQTYITYQLAPKWEINFLGNLANNNYKFTPYSRETSFGTAEHPKNFKVYFDGRER
                     DRFQTLFGALTLKHNPNENTELGLQASAFKSKEEEGYDIAGEYWLSENGAENPDDDASA
                     AMSVGRYHEHARNRLNSTVMNVGHYGMARLLNNTLKWGATVQMEKINDKISEWEKRDSS
                     GYSLPQTGNNVSVYSNLFSDNQIESTRFSAYAQDAFKFRTKQGLFTLVAGVRGSYWTYN
                     KEFLFSPRASLGFIPNFDQDLTLRFATGLYYQSPFYKELRRVDKDKNGNNITVLNKDLK
                     SQRSIHFILGGDYTFRAVDRNFKVTAEMYYKKLDNLNPYTVDNVKIRYYGENCAKGYAM
                     GLDVKFFGEFVPGTDSWISFSLMKAQQTIRETTTVPMANSQGYNISLFFQDYFPGYKRV
                     KLNLKGVLSGGLPQTIPGKGYEAGYFRTPAYKRVDIGLSYQLAGGTDAIMDRGFFRHLK
                     NIWLGLDVFNILDIKNVSSYYWITDVYNVQYAVPNYLTGRQLNVRLIVDF"
     CDS             2547..2957
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg206_2"
                     /sec_met_domain="Glyoxalase_4 (E-value: 1.3e-27, bitscore:
                     85.0, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELTHIEHLGIAVKSIEACLPYYEGVLGLKCYNIEVVADQKVKTA
                     FFKVGQTKIELLEPTSEDSTIAKFIEKKGEGIHHIAFAVPDVQAALNEAEEKGVKLIDK
                     APRGGAEGLNIAFLHPKSTCSVLTELCMPGNK"
     CDS             2994..4547
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg206_3"
                     /sec_met_domain="CT_Btheta (E-value: 5e-293, bitscore:
                     960.5, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKVKELIALREQARLGGGEKRIESQHKKGKYTARERIAML
                     LDEGSFEEFDMFVQHRCTNFGIEKTKYLGDGIVTGYGTIDGRLVYIFAQDFTVFGGALS
                     EALAMKICKVMDQAMKMGAPVIGLNDSGGARIQEGVNALAGYAEIFQRNILASGVVPQI
                     SGIFGPCAGGAVYSPALTDFNIMTRGTSYMFLTGPKVVKTVTGEDVTQEQLGGASVHTT
                     KSGVAHFAVDTEEDGLQLIRKLLSFLPQNNLEETPLVECKDPIDRLDDVLNDIIPDNAN
                     QSYDMYEVIGTIVDNNEFLEVHADYAKNIIVGFARFNGQSVGIVANQPKVMAGCLDSNA
                     SRKAGRFVRFCDAFNIPLVTLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKITV
                     TLRKSYGGAYCVMSSKHLRGDMNYAWPTAEIAVMGPSGAVEVIFAKEVAAAEDPKACAA
                     EKEAEYKKAFANPYNAAQYGYIDDVIEPRNTRFRIIRALQQLQTKKLSNPAKKHDNLPL
                     "
     CDS             4569..5456
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg206_4"
                     /sec_met_domain="OAD_gamma (E-value: 1.4e-13, bitscore:
                     40.1, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINKKIGVLLLFALLISFGAKAQRATSMRINEVLVINEDNFVDDY
                     GKRHGWIELFNTSAGTVNIAGCYLTDDKNNPMKYPIPKGDVLTQIQPRQHTLFWADGQP
                     GRGTFHVNFVLDPSKENYIALYDADGKTLIDEVTIPAGQMADISYGRVIDGKDEWAQLK
                     KVTPSTNNLTLDSNEKIDNFKQNDSLGIGMTITAMAVVFLGLFLLYIIFKQIGRLSISA
                     SKRNAQKAAGTTSVSVDAGQESGEIFAAIATALYEMSDDNHDIEHTVLTIHKVQRTYSP
                     WSSKLYGLRQTPHK"
     CDS             5478..5909
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 64.8; E-value:
                     1.6e-20)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg206_5"
                     /sec_met_domain="Biotin_lipoyl (E-value: 1.5e-21, bitscore:
                     64.8, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSFKYTINGNVYKVHINSVVDDIADVEVNGTPYQVKLEKPAKKQ
                     MVTLKRPAQAPTTASGDPVVTRPAASTTQGAVKTPLPGVILQVKCNVGDTVKRGQTLII
                     LEAMKMENNINADRDGKIIEIKVHKGDSVLEGADLVVIG"
     CDS             5914..7053
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg206_6"
                     /sec_met_domain="OAD_beta (E-value: 7.3e-153, bitscore:
                     497.2, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQESFLTFLGENLQLFLTYTGVYNATPGHLIMILVGLLFIFLAIK
                     YEFEPMLLIPIGFGILIGNIPFKDAGLQVGIYEQGSVLNILYQGVTSGWYPPLIFLGIG
                     AMTDFSALISNPKLMLIGAAAQFGIFGAYTIALQMGFEPNQAGAIGIIGGADGPTAIFL
                     SSKLAPNLMGAIAVSAYSYMALVPIIQPPFMRLLTTKKERLIRMKPPRAVSSTEKIIFP
                     IVGLLLTCFLVPSGLPLLGMLFFGNLLKESGVTRRLAETARGPLIDTITILLGITVGAS
                     TQATQFLTLNSIKIFGLGALSFVIATCAGVLFVKLFNLILKDGNKINPLIGNAGVSAVP
                     DSARISQVVGLEYDPTNYLLMHAMGPNVAGVIGSAVAAGI"
ORIGIN
        1 tagattatga agattcgtgc gatagctgcg ctgctattta tacttatttc cgtgagtgcc
       61 tttggcgagg gccgcataaa aatcactggt tatgtccgtg acgccgacgg taaccctctg
      121 gaattagtga atgtccgggt taagaacacg ttgatcggct ccatgaccaa cgagaaggga
      181 tattattcct tttccatatc gccgggggat tctatctccg ttatttactc ttgtctggga
      241 tataataagg ctgagcgtat cattccctcg gcacaagcgg atatgcgcct gaacgtacag
      301 atgaacaata cctcatttga tttaggggaa gtatccgtta ctgccatccg caagcagacc
      361 acgaccatgg agtccctaaa tgcggacaaa attaagttat tgcccgatcc ctccggaggt
      421 agtatagaga gcttggtcgt tacgtttgcc ggagtatcgt ccaataacga gttaagttcc
      481 cagtattccg tacgtggagg tagttatgat gaaaatatcg tttatgtgaa tgggatcgag
      541 gtattccgtc cgcttctgat tcgctcggga caacaagagg gccttagttt tatcaatccg
      601 gacctgacgg aggcggtcaa tttcgccgcc ggtggcttcg aggctcgtta cggagacaag
      661 atgagttccg tgctggatat tacctataaa aagcctaaga tattcgaagg ctcggcttcc
      721 gcgagcttgt tgggagcgaa tgcttatgta ggcagttcta tcggtaaatt tacccaagta
      781 acgggtttcc gctttaaaag cggtcggtct attttgggta ccatggatac agacgctgaa
      841 tacgacccta aatttatcga tctgcaaact tacatcacgt accaattggc ccctaaatgg
      901 gaaatcaatt tcttaggaaa cctcgctaac aataattata aattcacccc ttatagccgg
      961 gaaacctctt tcggtacagc cgagcatccc aagaacttca aagtctattt cgacggaagg
     1021 gaaagagacc gtttccaaac cttattcggt gcgcttacat tgaaacacaa ccccaatgag
     1081 aacacagagt tgggacttca agcctccgct ttcaaaagca aggaagaaga gggatacgat
     1141 atcgccggag aatattggct gagcgagaac ggagcggaaa atccggatga cgacgcgtca
     1201 gccgccatgt ccgtaggccg ttatcacgag cacgcacgaa accgtttgaa ctccaccgtc
     1261 atgaatgtcg ggcactatgg gatggcccgc cttttaaaca atacgttgaa atggggagcc
     1321 acggtacaaa tggagaaaat caatgataag atcagtgaat gggaaaaaag ggattcctca
     1381 ggttattctt tgccccaaac cggtaataac gtaagtgtat attcgaacct cttttctgat
     1441 aatcagatag aaagcacacg cttttccgct tatgcgcaag acgcattcaa attcaggacc
     1501 aagcaaggtc tgttcacgtt agtcgcaggg gttagaggta gttattggac ttataataag
     1561 gagttccttt tcagtccccg tgcctcattg ggctttatcc cgaacttcga ccaagacttg
     1621 acgctccgtt tcgccaccgg actgtattat caatcgccct tctacaagga attacgtaga
     1681 gtagacaaag ataagaacgg caataatatc acggtattga acaaagatct aaagtcacaa
     1741 cgctccatcc atttcatatt gggaggagat tatacgttcc gtgccgtaga ccggaatttc
     1801 aaggtgaccg ccgagatgta ctataaaaag ctggacaatc tgaatcccta caccgtagat
     1861 aacgtcaaga tccgctatta cggtgagaac tgcgccaaag gttacgccat gggactcgat
     1921 gtcaaattct tcggagaatt cgtaccgggt accgactcat ggatcagctt ctccttgatg
     1981 aaagcccagc aaaccatccg ggaaacaacg accgttccta tggccaatag ccaaggctac
     2041 aacatctcac tcttcttcca agattatttc ccgggctata aacgagtcaa gctaaatctg
     2101 aaaggagttc tatccggagg acttccccag acaatcccgg gcaaaggata cgaagccggc
     2161 tatttccgta cgcccgccta caaacgtgta gatatcggcc tctcctatca attggcagga
     2221 ggcacggacg ctatcatgga caggggcttc ttccgccatt tgaaaaacat ttggctaggt
     2281 ctggatgtat ttaacatatt agacatcaaa aacgttagtt cctactattg gataacagat
     2341 gtatataatg tccaatacgc agttccaaac tatctgaccg gacgtcaatt gaacgttcgt
     2401 ctgattgtcg atttttaata aaatgtatct ttaaacacat ttactgggag ataaaaacaa
     2461 aaaattattt cctcattcat aaaaagtagt gtacatttgc acacaataga aacaaacatt
     2521 tactaaatct ttaaattatt attgacatgg aacttacaca tatcgaacat ttaggtatcg
     2581 cagtgaagag tatcgaggct tgtttaccct attatgaagg cgttcttgga ttaaaatgct
     2641 acaatatcga agtagtagca gaccaaaaag taaaaaccgc atttttcaag gtaggacaga
     2701 ctaagattga attactagag ccgaccagtg aagatagcac gatcgcgaaa tttatcgaga
     2761 aaaaaggtga aggtatccac catatcgcat tcgcggtacc tgatgtacag gcagctttga
     2821 acgaggctga ggaaaaaggc gttaaattaa tcgataaagc tccccgtggt ggcgcggaag
     2881 gcttgaacat cgctttcctt cacccgaaat caacttgcag cgtattgaca gaactttgca
     2941 tgccgggcaa caaataatta atccgttcat ttctaacaac aaatcaaaat acaatgagta
     3001 accagcttga aaaagtaaaa gagctcatcg cacttcgtga gcaagctcgc ttgggtggag
     3061 gagagaaaag aatcgaatca cagcacaaaa aaggcaaata taccgctcgt gagcgtatcg
     3121 ccatgttgct tgacgaaggt agtttcgagg aattcgacat gtttgttcaa caccgttgta
     3181 caaacttcgg tatcgagaaa actaaatatt taggcgatgg tatcgtaaca ggttatggta
     3241 cgatcgacgg acgtttggta tatatcttcg ctcaagattt caccgtattc ggtggagcct
     3301 tgtctgaggc tttggctatg aagatctgta aagtaatgga tcaagccatg aagatgggcg
     3361 ctcccgttat cggtttgaac gactccggtg gagctcgtat ccaagaaggt gtaaacgcct
     3421 tggcaggata cgcagagatt ttccaacgta acatcttggc ttccggtgtt gttccccaga
     3481 tttccggtat cttcggccct tgcgccggtg gagccgttta ttctccggct ttgacagact
     3541 tcaacatcat gacacgtggt accagctata tgttcttgac tggtccgaaa gtcgtaaaaa
     3601 ccgtaacagg tgaggatgta acccaagagc agttgggtgg agccagcgta cacactacca
     3661 aatcaggtgt agcccatttc gctgtcgata cagaagagga tggtttgcaa ttgatccgta
     3721 aattgctcag cttcttacca cagaacaact tggaagaaac tccgttagtt gagtgcaaag
     3781 acccgatcga tcgtctggat gatgtattga acgatatcat tcccgataac gccaaccaat
     3841 cttacgatat gtatgaggtt atcggtacga tcgtcgataa caacgagttc ctagaggtcc
     3901 atgcggacta cgctaagaat atcatcgtag gtttcgctcg tttcaacgga caatccgtcg
     3961 gtatcgtagc taaccagccg aaggttatgg caggatgctt ggatagcaac gcatctcgta
     4021 aagcaggtcg cttcgttcgt ttctgcgacg ctttcaatat tcctttggta acattggttg
     4081 acgttccggg attccttccg ggtacaggtc aggaatacaa cggtgtaatc cttcacggcg
     4141 ctaaattgct ttacgcttat ggtgaggcta ccgttcctaa gattaccgtt acattgcgta
     4201 agtcttacgg tggagcttat tgcgtgatga gttctaaaca tttacgtggt gatatgaatt
     4261 acgcatggcc gacagccgag atcgccgtta tgggcccgag cggtgccgta gaggttatct
     4321 tcgccaagga agtagcagcc gctgaagatc cgaaagcatg cgcagcagag aaagaagctg
     4381 aatataagaa agcattcgct aatccttata acgcagctca atacggttat atcgacgatg
     4441 ttatcgaacc gcgtaacact cgtttccgta ttattcgtgc tttgcagcaa ttgcagacta
     4501 agaagttaag caatcctgct aagaaacatg ataacctgcc tctataatcc gtaaaacagg
     4561 agatgaatat gataaataag aaaatagggg tattgctact gttcgctttg ctcatttcat
     4621 tcggggcaaa ggcacagcgc gcaacctcca tgcgtattaa tgaagtattg gttatcaacg
     4681 aggataactt cgttgatgac tatggcaaac gtcatggctg gattgagttg ttcaacactt
     4741 cggccggaac ggtaaatatc gcgggatgtt atttgacaga cgacaaaaac aatcccatga
     4801 aatatccgat cccaaaggga gacgtattga ctcagatcca accccgccag cacacactat
     4861 tttgggctga cggacagccg ggcagaggta cattccacgt taacttcgta ttagatccct
     4921 ctaaggagaa ttatatagct ctgtatgatg cagatggtaa aacattgatc gacgaagtta
     4981 cgatccctgc cggacaaatg gctgatatca gttacggtag agtgatcgat ggtaaagatg
     5041 aatgggcaca gctgaagaaa gttactccca gtacgaataa cctaacattg gattctaatg
     5101 agaaaatcga taatttcaaa cagaatgact ctttaggtat cggtatgacc attaccgcta
     5161 tggctgtagt gttcttggga ttatttttgt tatacatcat ctttaagcag atcggtagat
     5221 tgtctatatc cgcgagcaaa cgtaacgctc aaaaagctgc gggaacaaca agtgtatcgg
     5281 ttgacgccgg acaagagtct ggtgagattt ttgccgctat cgctactgct ttgtacgaga
     5341 tgagtgatga caatcatgac atcgagcaca cggttcttac gatccacaag gtacaaagga
     5401 cttattctcc ttggagttca aaactctacg gtttgcgtca aaccccacat aagtaattat
     5461 ctaaaaacga acaaagaatg aaaagtttta aatataccat taacggtaac gtatataaag
     5521 tacacatcaa ttctgtagtg gatgacatcg cagatgttga agtaaatggt acaccttatc
     5581 aagtaaaatt agagaaaccg gcgaagaaac aaatggttac attgaaacgt ccggctcaag
     5641 caccgacaac agcaagtggc gaccctgtag ttactcgtcc ggcagcctct actacacaag
     5701 gtgctgttaa gactccgctg ccaggtgtta tcttgcaggt taagtgcaac gtaggtgata
     5761 ccgtgaagag aggtcaaaca ttgattatcc ttgaggctat gaagatggag aacaacatca
     5821 acgcagaccg tgacggtaag attatagaaa ttaaagtaca caagggagac tctgtgctag
     5881 aaggtgctga tctcgtagta atcggataag actatgcaag agagcttttt aacattctta
     5941 ggtgagaact tacaactgtt ccttacctat acaggtgtat acaacgctac tccgggacat
     6001 ctcatcatga ttctggtagg tctgttgttt atattcctgg cgattaaata tgagtttgaa
     6061 ccgatgcttt tgatccctat cggatttggt atcttgatcg gtaatatccc tttcaaggac
     6121 gcaggtcttc aggtaggtat ttatgagcaa gggtctgtac tgaacatcct ctatcagggt
     6181 gtgacctctg gatggtatcc gccattgatc ttcctcggta tcggggccat gaccgacttc
     6241 tccgcattga tctccaatcc taagttgatg ttgatcggtg cagcggctca gttcggtatc
     6301 tttggtgctt atacgattgc tcttcaaatg ggatttgagc cgaaccaagc aggtgctatc
     6361 ggtattatcg gtggtgctga cggtccgacg gctatcttcc tgtcttctaa gttagcgcca
     6421 aacttaatgg gtgcgatcgc ggtatccgct tactcataca tggcgttggt tcctattatc
     6481 caaccgccgt tcatgagatt gcttacgact aagaaagagc gtttgatccg tatgaaaccg
     6541 ccgagagccg tttcttccac ggaaaaaatt atcttcccga tcgttggttt gttgcttact
     6601 tgcttcttgg ttccgtccgg tttaccattg ttaggtatgc tattcttcgg aaacttattg
     6661 aaagaaagtg gcgtgactcg tcgtttggca gagactgctc gtggtccgct gatcgataca
     6721 atcacgatct tattgggtat cacggtaggt gcttctaccc aagctacaca gttcttgaca
     6781 ttgaactcta tcaagatctt cggtctaggt gcgttatcat tcgtgatcgc tacttgcgcc
     6841 ggtgtattgt tcgttaagtt attcaattta atattgaaag acggcaataa gatcaatccg
     6901 cttatcggta acgccggtgt atccgccgtt cctgactcag ctcgtatctc acaagttgta
     6961 ggtttggaat atgacccgac caactacttg ttgatgcacg ctatgggtcc gaacgtagca
     7021 ggtgtaatcg gttccgctgt agctgccggt atc
//
