LOCUS       c00038_gnlPro..        14309 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ALIJMEEH_38.
ACCESSION   c00038_gnlPro..
VERSION     c00038_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 18:15:35
            Original ID  :: gnl|Prokka|ALIJMEEH_38
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14309
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14309
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[5750:9995](-)"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      complement(5751..9995)
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
     cand_cluster    1..14309
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /kind="single"
                     /product="Others_HGD_unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14309
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Others_HGD_unassigned"
                     /region_number="1"
                     /rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1,
                     HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and
                     minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2,
                     AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF,
                     ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C,
                     Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and not (minimum(2,
                     [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /tool="gutsmash"
     CDS             25..246
                     /locus_tag="ctg38_1"
                     /transl_table=11
                     /translation="MKGSINMNENEKIVTVPYLLTVKQASDYFNIGARVIRALADADVD
                     YSFHVYNGNRLMIKREAFENFLKTAQTV"
     CDS             370..1587
                     /locus_tag="ctg38_2"
                     /transl_table=11
                     /translation="MGKCRRKLKDGEYFNSSNNRYEYHYTDRLGKKRVITSARLEPNDP
                     LPKSKRGGKSLREKEAEILKLLQNNIDVDGGKITVYETTLKFLEVLYAKKNITYNTKQS
                     YSRICRTLNNTTLGHMAICDVKPEHCDEWFVTMKAKYRGSAMQTDLSLIKRTFEFAVDR
                     DWIVKNPMKNLTVSRDDGTSRNPVSVEKMQSFLDFVKTEKHSHHCWELIHVLFWTGMRA
                     SEICGLTLDDLDFENRVIYVNKQVQKQDGVRVVTKVKSKNGIRVIPMTHEVEEALKAEI
                     EKRHLIEEPVLYGEDGVTAYSGFVFLSTRRRMPMMRENVEEYMKNCIKRYNERYSDDPM
                     PYCVPHVARHTFCTNLQQNGINPVTLQHIMGHGSIKTTLSWYTGVKAVPEQVAEMDGIV
                     TKILTL"
     CDS             1748..2386
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg38_3"
                     /sec_met_domain="GATase (E-value: 4.5e-31, bitscore: 97.8,
                     seeds: 97, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIAIIDYDAGNIKSVEKALHYLGEETTVTRDPQTLLNADKVILPG
                     VGSFGRAMENLHTYGLVPVIHEIVEKKTPFLGICLGLQLLFESSEETPGVEGLGILKGK
                     IVKIPPAPGLKIPHMGWNSLHFQNNGRLFQGIPEQTYVYFVHSYYLQAEEPEIVKATTE
                     YSTCIHASVEKDNVFACQFHPEKSSKWGLKILENFAAVGKDGNTEKEGK"
     CDS             2388..3146
                     /locus_tag="ctg38_4"
                     /transl_table=11
                     /translation="MFTKRIIPCLDVNNGRVVKGVNFVQLRDAGDPVEIAKAYDAAGAD
                     ELVFLDITASCEQRDTVVDMVRRVAANVFIPFTVGGGIRTVDDFKKLLREGADKISVNS
                     AAIDRPELISEAADKFGSQCVVVAIDAKRREDGGWNIYKHGGRLDTGIDAIEWAKKVEA
                     LGAGEILLTSMDCDGTKAGYDLALTRAIADAVSIPVIASGGAGTLEHFYDALTEGGADA
                     ALAASLFHYKELEISQVKDYLSDRGISVRR"
     CDS             3179..3853
                     /locus_tag="ctg38_5"
                     /transl_table=11
                     /translation="MSAISGDWLEALKGEFHQPYYAKLYKTVMTEYQTRKIFPPADDLF
                     NAFHFTPLNEVKVVILGQDPYHNDGQAHGLCFSVKRGVETPPSLVNIYQELHDDCGCYI
                     PNNGYLEKWAKQGVLLLNTVLTVRAHQANSHRGIGWEQFTDAAIQVLNEQDRPIVFLLW
                     GRPAQMKKSMLNNPKHLILEAPHPSPLSAYRGFFGCKHFSKTNEFLVANGLEPIDWQIE
                     NI"
     CDS             3941..5527
                     /locus_tag="ctg38_6"
                     /transl_table=11
                     /translation="MIAAMISKVIGLLYKSPLSNIIGSLGMGYTSLAQNAYMILLMIAS
                     FSIPQAVSKLISERIALKDYRNAHKFFKGAMIYAMVIGGVVGLFCLFGAGLIIPQNQKD
                     AIPALQILAPTIFLSGILGVFRGYFQAYRNMMPTSISQIIEQVFNAAVSLLAAWGFINA
                     FSDGTENSIAKWGAAGSTVGTGAGVVTALAFMLLVYGVNRRKILHRVARDHRHQEESYK
                     EIFRVIILVVSPIILSAFVYNVNAYINGYLFSDILGRRGGDAAQIGILYAEYATYFMTI
                     INIPLTLSSTAPTSMIPEVSALYATGDIEATRECIDQTVQLSMVVSAPCAMGLAVLAQP
                     IVFLLYGNSTGLAANLLILGSFSILLNGMSNISNGVLQAIGQQRIPVITAAIALVVDIV
                     VVVVLLFTTNLGVYALLIAMVIYSVVVCVLNDRAMKKYLQYKNPWKEGYLYPVLASVPM
                     GIVAGCICYGLNIFVKSNFICLIVSIPVAAVVYLFAYLIISKPSESQLRRIPGGSYLIR
                     IAEKLPFWQNN"
     CDS             complement(5751..9995)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: BcrAD_BadFG"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg38_7"
                     /sec_met_domain="HGD-D (E-value: 8.9e-64, bitscore: 205.8,
                     seeds: 370, tool: rule-based-clusters)"
                     /sec_met_domain="BcrAD_BadFG (E-value: 5e-38, bitscore:
                     120.7, seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNYKTLGIDIGSTTVKIAILDENENLIFADYKRHFANIQETLADL
                     LQEAFDQYGEMTLHPVITGSGGLTLANHLGVPFTQEVIAVSTSLQKLAPKTDVAIELGG
                     EDAKIIYFENGNVEQRMNGICAGGTGSFIDQMASLLQTDATGLNEYAKDYKALYPIAAR
                     CGVFAKTDIQPLINDGATKPDLSASIFQAVVNQTISGLACGKPIRGHVAFLGGPLHFLS
                     ELRESFIRTLKLDGEHTIIPENSHLFAAIGSALNAKEDNSISLTEMKDRLRNSIKLDFE
                     VERMEPLFASQEEYDAFAKRQSSYKVKTGDLATYKGNCYLGIDAGSTTTKTALVGEDGT
                     LLYSFYSSNNGNPLKTTIRSIKEIYELLPKDAKIAYSCSTGYGEALLKAALLLDEGEVE
                     TVSHYYAAAFFDPEVDCILDIGGQDMKCIKIRNKTVDSVQLNEACSSGCGSFIETFAKS
                     LNYTVQDFAKAAVFAQHPIDLGTRCTVFMNSKVKQAQKEGAEVSDISAGLAYSVIKNAL
                     YKVIKVSDASELGKHIVVQGGTFYNDAVLRSFEKIAGCEAIRPDIAGIMGAFGAALIAR
                     ERHQEGAETTMLSIDKINELKYTTSMANCRGCTNNCRLTINKFSGGRQYVSGNRCERGI
                     GKEKNKDHIPNLYEYKYKRIFSYTPLTADKATRGKVGIPRVLNMFENYPFWYTFFTELK
                     YEVVLSPTSTRKIYELGIESIPSESECYPAKLAHGHVTWLIRNGVKFIFYPCIPYERNE
                     FPDAVNHYNCPIVTSYAENIKNNVDELNDPSITFRNPFLAFTSEEILANRLVEEFKDIP
                     AEEVKAAVHKGWEEMAAARRDVQKKGEETLKYLEDTGRHGIVLAGRPYHIDPEIHHGIP
                     DLINSYGIAVLTEDSISHLAPVERPIRVNDQWMYHSRLYAAANYVKTRDDLDLIQLNSF
                     GCGLDAVTTDEVYEILDGSDKIYTCLKIDEVNNLGAARIRIRSLIAAIRAKKAQGQKRT
                     VKPASIDKVSFTKEMRKDYTILCPQMSPFHFSLLQAAFNSCGYNLEVLPNDNKHAVDVG
                     LKYVNNDACYPSLIVVGQIMDALLSGKYDLNKTAVVMSQTGGGCRASNYIAFIRRALKK
                     AGMEQIPVISVNLSGLESNPGFKLTLPLVKKVAYGAVFGDILMKCVYRMRPYELEEGIV
                     NRKHKIWEQRVISFLSGSSISHSQFKKMCREMVHEFDTIPISDVKKPRVGIVGEILVKF
                     LPAANNHLAELLESEGAEAVVPDLIDFMCYCFYNQNFKVENLGFKKSKATMANWGIKAI
                     EWVRKPASEALAQSRHFAPPADIRNLAKMASPIVSTGNQTGEGWFLTGEMMELIHGDVP
                     NIVCIQPFGCLPNHIVGKGVIKEIRREYPTANIVAIDYDPGASEVNQLNRIKLMLSTAQ
                     KNLKKAEEKMHK"
     CDS             10442..11593
                     /locus_tag="ctg38_8"
                     /transl_table=11
                     /translation="MAEYKLLKTEGRAKRAEFHTVHGTIQTPVFMNVGTIGAIKGAVST
                     MDLQQIGTQVELSNTYHLHVRPGDKIVKQLGGLHKFMVWDKPILTDSGGFQVFSLAKLR
                     KIKEEGVYFNSHIDGHKIFMGPEESMQIQSNLASTIAMAFDECPSSVADRDYVQKSVDR
                     TTRWLARCKAEMARLNSLPDTINKEQLLFGINQGAVYEDIRIEHAKAISEMDLDGYAVG
                     GLAVGETHEEMYRILDAVVPYLPQNKPTYLMGVGTPANILEGVERGIDFFDCVYPSRNG
                     RHGHVYTNHGKMNLFNAKYELDTRPIEEGCQCPACQHYSRAYIRHLLKAKEMLGMRLCV
                     LHNLYFYNHMMEEIRDALDAGNFAEYKKMRLEGFEEGKINSKR"
     CDS             11656..11784
                     /locus_tag="ctg38_9"
                     /transl_table=11
                     /translation="MMCSDALIRLFCMKTRFHTEGNGDYKWIAKQLFSMSSRQDGL"
     CDS             11842..12141
                     /locus_tag="ctg38_10"
                     /transl_table=11
                     /translation="MNASSGMGMVGAIVWMVVLFGIMYFLMLRPQKKEQKRLQAMLNDM
                     EVGDSIVTTGGFYGVVIDMTEEDVIVEFGNNKNCRIPMRKQAIAEVEKAGSAAE"
     CDS             12330..13412
                     /locus_tag="ctg38_11"
                     /transl_table=11
                     /translation="MDYKIALIPGDGIGPEIVREAKKVLDKVCEKYGHSFSYSEVLLGG
                     ASIDVHGVPLTDEAIATAKSSDAVLMGSIGGDAKTSPWYKLEPSKRPEAGLLAIRKALN
                     LFANLRPAYLYNELRKACPLRDEIIGDGFDMIIVRELTGGLYFGERQTIEENGVKKAID
                     TLSYNENEIRRIAIKAFEIARKRRNKVTSVDKANVLDSSRLWRKVVEEVAKDYPDVTLE
                     HMLVDNCAMQLVRDPKQFDVILTENMFGDILSDEASMVTGSIGMLSSASLNETKFGLYE
                     PSHGSAPDIAGQDKANPIATILSAAMMLRFSLDMDKEADAVEAAVQKVLTEGYRTGDIM
                     SEGCKLVGTKEMGDLIAAAL"
     CDS             13520..14308
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ILVD_EDD"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg38_12"
                     /sec_met_domain="ILVD_EDD (E-value: 3e-99, bitscore: 322.5,
                     seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRSDAVKTGTQQAPHRSLFNALGMTKEEMDRPLVGIVSSYNEIVP
                     GHMNLDKITQAVKLGVAMAGGTPVMFPAIAVCDGIAMGHVGMKYSLVTRDLIADSTEAM
                     AMAHQFDALVMIPNCDKNVPGLLMAAARLNVPTVFVSGGPMLAGHLNGHKTSLSSMFEA
                     VGAYAAGKLDEDGLTECEMKTCPTCGSCSGMYTANSMNCLTEVLGMGLKGNGTIPAVYS
                     ERIRLAKHAGMQVMEMYRKNIRPRDIMTKEAILNALTVDMA"
ORIGIN
        1 gaacaggaca cataaaatga gattatgaaa gggagtatta acatgaatga aaatgaaaaa
       61 attgtgactg ttccgtattt gttaacagta aaacaggcat cagattattt taatattggt
      121 gcaagagtaa tcagagcgtt ggcagatgct gacgttgatt atagctttca cgtgtataac
      181 ggtaacaggc tgatgattaa acgtgaggct ttcgagaatt tcttaaaaac agctcaaaca
      241 gtgtaacagt gtagatttat gtatatttat gttgtcttaa tgtagcaaga aggcgcgtaa
      301 cgtgttataa ttcattatga tttatagcat tctacgggct ttcttttttt aaggaaagag
      361 gaaagctgaa tgggaaaatg tagaaggaaa ttaaaagatg gggaatattt taatagttcc
      421 aacaatcgct atgaatatca ttatacggat aggttaggca agaaacgcgt tatcacatct
      481 gcacgacttg aaccaaacga cccgttacca aaaagcaagc ggggcgggaa gtctctgagg
      541 gaaaaagaag ctgaaatctt aaagctgtta cagaataata ttgacgtaga cggtggcaaa
      601 ataacagtat acgagacaac gctgaaattt ttagaggtgt tatatgcaaa gaaaaacatt
      661 acatacaaca caaaacagag ctattcacgt atctgccgga cgttaaacaa tacgacgctc
      721 ggtcatatgg caatttgcga cgtaaagccg gagcattgtg acgaatggtt cgtaaccatg
      781 aaggcgaaat acagaggttc agcaatgcaa acggacttgt ctttaatcaa acggacgttt
      841 gaatttgcgg ttgatcgtga ttggatagtc aaaaatccaa tgaagaactt aacagtatcg
      901 cgtgatgatg gcacgtcacg caacccggtg agtgttgaaa agatgcagtc tttccttgac
      961 tttgtgaaaa cagaaaagca tagtcaccat tgttgggaat tgattcatgt gttattctgg
     1021 acggggatga gagcgtctga aatctgtggt ttgacgttgg atgaccttga ttttgagaat
     1081 cgtgtcatct atgtaaacaa acaggtacag aagcaggacg gcgtacgtgt ggtaacaaag
     1141 gtaaaaagca aaaacggaat acgtgttatc ccaatgacac acgaagtaga agaagcacta
     1201 aaggcagaaa ttgaaaaacg tcacttaata gaggagcctg tcctctatgg tgaagatggc
     1261 gtaactgcct attctggctt tgtgtttctg tctacacgcc gacgtatgcc gatgatgcgg
     1321 gagaacgttg aggaatacat gaaaaattgt atcaaacgct ataatgagcg ttattcagac
     1381 gaccctatgc cttactgcgt cccacacgtt gcccgccata cattctgtac aaatcttcaa
     1441 cagaatggaa tcaacccggt gacattgcaa catattatgg gacacggcag tattaagacg
     1501 acgttaagtt ggtatacagg cgtgaaggct gtgccggagc aggtggcaga gatggatgga
     1561 attgttacaa aaatattaac cctgtaacat tttagtattt cgcttctgaa atactaaaga
     1621 aatactaaaa attacactaa aagatatact aaattataaa tatttatgtt aagatatgca
     1681 aagtaacaac aagtgagaaa cagcataatt acagcaaagg gcacgacata atgaggagta
     1741 aaaaattatg atagcaataa ttgactatga tgccggaaat attaaaagtg tagaaaaagc
     1801 acttcattat cttggggaag aaacaacagt aacccgcgat ccgcagactt tgttaaatgc
     1861 ggataaagta atcctgccgg gcgtgggaag ctttggacgg gcgatggaga atcttcatac
     1921 atacggactt gtacctgtga tccatgagat tgtagagaag aagacgccat ttcttggaat
     1981 ctgcctggga cttcagctcc tttttgaaag cagcgaggag acaccggggg tggaaggcct
     2041 tggaatcctg aaagggaaaa ttgttaagat tccgcctgcg ccggggctta agattccaca
     2101 tatgggatgg aattccctgc attttcagaa taatggcaga ctgtttcagg gaatcccgga
     2161 acagacctat gtatattttg tgcattccta ttatctgcag gcagaggagc ctgagattgt
     2221 aaaggctact acagaataca gcacctgtat tcatgcttcc gtagaaaagg acaatgtatt
     2281 tgcctgccag ttccatccgg aaaagagcag caaatgggga ctgaagatac ttgaaaattt
     2341 tgctgctgtg ggaaaagacg gcaatactga gaaggaggga aaataagatg tttacaaaga
     2401 gaattattcc ctgcctggat gtaaataacg gacgtgtggt aaagggcgta aattttgtgc
     2461 agcttcgcga tgcgggtgat ccggtggaga ttgccaaagc ctatgatgca gcaggagcag
     2521 atgaactggt gtttctcgat attacagcat cctgcgaaca gagagatacg gtagttgaca
     2581 tggtaagacg ggttgctgcc aatgtattta tcccgtttac agtaggcggc ggtatccgta
     2641 ctgtagatga tttcaagaaa ctgctgagag aaggagcaga taagatttcc gtaaattctg
     2701 cagcaattga cagaccggaa ctgatcagtg aggcggctga caagtttgga agccagtgcg
     2761 tagttgtggc tattgatgcc aagcgcagag aagacggcgg atggaatatt tacaaacatg
     2821 gcggaagatt agatacaggg attgatgcca tagagtgggc aaagaaagtg gaagctctgg
     2881 gtgcagggga aatccttctt accagtatgg actgtgacgg tacaaaagca ggatatgatc
     2941 tggctcttac cagagcaatt gctgatgctg tctccattcc tgtgatcgca tcaggcggtg
     3001 caggtacact ggagcatttt tatgatgcac tgaccgaagg gggagcagat gctgcactgg
     3061 ctgcgtcttt gttccattat aaagaactgg agatttctca ggtgaaggat tatctgtctg
     3121 acaggggaat ttctgtcaga cgatgaccac gaaaaatata agaggtgaag gataaggtat
     3181 gtcagcaatt tcaggtgact ggctggaagc cctgaagggg gagtttcacc agccgtatta
     3241 tgcgaaatta tataaaacgg tgatgacaga atatcagacc aggaagattt ttcctcctgc
     3301 ggatgatctg tttaatgcat ttcattttac accgttgaat gaagtgaagg tagtgattct
     3361 gggtcaggat ccctatcata atgacgggca ggctcatggg ctttgttttt ccgtaaagag
     3421 aggagtggag acgccgccgt ccctggtgaa tatttatcag gagcttcatg atgactgtgg
     3481 atgctatatc cccaataacg gctatctgga gaagtgggcg aagcagggag tgcttcttct
     3541 gaacacagtt ctgactgtac gcgctcatca ggcaaattca cacaggggga tcggctggga
     3601 gcagtttacg gatgctgcga tccaggttct gaatgagcag gaccgtccta ttgtatttct
     3661 gctctgggga cgtccggcgc agatgaaaaa atccatgctg aataatccga agcatctgat
     3721 tctggaggca cctcatccaa gtcctctgtc tgcttacagg ggatttttcg gatgtaaaca
     3781 tttcagtaaa acaaacgaat ttcttgttgc caatggtctg gaaccaatcg actggcagat
     3841 agaaaatata taagaaaaga ggtaatgtgt agtcaggtaa aagacacaca gtgataacat
     3901 gaatcagaaa aacaatttag taaaaaatgc atcctttctg atgattgcag ctatgatctc
     3961 caaggtgatc ggtcttctgt acaagagtcc cctttccaat attatcggaa gccttggaat
     4021 gggctataca agtcttgcac agaatgccta tatgatcctt ctgatgatcg catcctttag
     4081 tattccacag gcggtatcca agctgatctc cgagcgtatt gctctgaagg attacagaaa
     4141 tgcacataag ttctttaagg gtgccatgat ctatgccatg gtgattggcg gagtggtcgg
     4201 tttattctgt ctctttggag cagggctgat catccctcag aatcagaagg atgcaattcc
     4261 ggcacttcag atcctggctc cgacgatttt tttgtccggt attcttgggg tattcagagg
     4321 atattttcag gcatacagaa atatgatgcc aacatctatc tcccagatca ttgagcaggt
     4381 atttaatgcg gcagtcagtc ttctggcagc ctggggattc atcaatgcat tctcagatgg
     4441 aacagagaac agcattgcaa aatggggggc agcaggttcc acagtaggaa ccggagccgg
     4501 agtggtgact gcattggcat tcatgcttct ggtatatggt gtgaaccgca gaaaaatcct
     4561 gcaccgggta gcgagagacc acagacatca ggaagagtcc tacaaagaga tttttcgtgt
     4621 gattatcctg gttgtttcgc cgatcattct cagcgccttt gtttataatg taaatgctta
     4681 tatcaatggg tatcttttct cggatattct gggaagaaga ggtggagatg cggcacagat
     4741 tggtatttta tatgcagagt atgctactta ctttatgaca attattaata ttcctctgac
     4801 gctgtccagt acggcaccta cttccatgat tccggaggtt tccgccctgt atgccaccgg
     4861 agacattgaa gcgaccagag agtgcattga ccagaccgta cagctttcta tggtagtttc
     4921 tgccccatgt gccatgggac tggcagtgct tgcacagccg attgtatttt tgctttacgg
     4981 aaattccaca ggactggcag ccaacctgct gatccttggt tctttttcga tcctgctcaa
     5041 tggaatgtca aatatttcca atggagttct gcaggcaatc ggacagcaga ggattccggt
     5101 gattacggct gcaatcgcac tggttgtgga tattgtggta gtggtagtgc tgctgtttac
     5161 tacaaacctt ggagtttatg cactgctgat cgcaatggtg atctattctg tggttgtatg
     5221 tgtgttaaat gacagagcca tgaagaaata tctgcagtat aagaatccat ggaaagaagg
     5281 atatctgtat cctgttcttg catctgttcc catgggaatt gttgcaggct gtatctgcta
     5341 tggactgaac atttttgtaa aatccaattt catttgtctg atcgtttcca ttcctgttgc
     5401 tgcggttgtt tatctgtttg cttacctgat catcagcaag ccgtcagaat cacagcttag
     5461 aagaattccg ggtggaagct atctgataag gattgcagag aaacttccgt tctggcagaa
     5521 taattaaaca ctgaaattat aaaaaacaaa agagttatat ttcatggttt aaatgtagtt
     5581 ctgaaataga aacacattta aaatttctga aatataactc tttttttgag cgcgtttgaa
     5641 aaatgctttt cgcaaagcag gatatgtaga ttgcgggaat gatttttcaa atacgctcta
     5701 aggcggatat attgcaaggt aaaatacatt gcaatatatc cattacggta ttatttatgc
     5761 attttttctt ctgctttttt caggtttttc tgagctgtgg agagcatcag tttgattcgg
     5821 ttgagctggt taacttcact tgcacccgga tcatagtcga tggctacaat attggctgtc
     5881 ggatattctc tgcggatctc tttgataaca cccttaccta caatgtggtt cggcagacat
     5941 ccgaaaggct ggatacaaac aatattcgga acatctccat ggatcagttc catcatctca
     6001 cctgtcagga accatccctc acctgtctgg tttccggtgg aaacgatcgg agatgccatt
     6061 tttgccagat ttctgatatc agcaggcggt gcaaaatggc ggctctgtgc aagagcttcg
     6121 cttgcaggct ttctcaccca ttcgattgct ttgattcccc agtttgccat ggttgccttg
     6181 gacttcttga atccaagatt ttctaccttg aagttctgat tatagaagca gtagcacatg
     6241 aaatcgatca gatccggtac aactgcctca gcgccttcag attccagaag ctctgccaga
     6301 tgattatttg cagcaggcag gaacttgaca aggatctcac ctacgatgcc gacacgaggc
     6361 tttttcacat cactgatcgg aatggtatca aattcgtgaa ccatttcgcg gcacattttc
     6421 ttaaactggc tgtggctgat actgcttccg cttaagaaag agatcacacg ctgttcccag
     6481 attttatgtt tcctgtttac gattccctct tccagttcat aaggacgcat acgatatacg
     6541 catttcatca ggatatctcc gaatacggca ccataagcaa ctttcttcac taatggaagc
     6601 gtaagtttga atccgggatt gctttccaga ccgcttaagt taacagagat aaccggaatc
     6661 tgttccatac cggctttctt taatgcgcgt cgtataaatg caatatagtt ggaagcacga
     6721 catccgccac ctgtctgtga catgacaacg gccgttttgt tcaggtcata tttaccggaa
     6781 agcagagcat ccatgatctg tcccacaacg atcagagacg gatagcaggc gtcattgttt
     6841 acatacttca gaccaacatc cactgcatgc ttattgtcat tcggaagcac ctccaggttg
     6901 tatccgcagg aattgaatgc tgcctgcagg aggctgaaat ggaacggtga catctgcggg
     6961 cagaggatgg tatagtcctt tctcatttcc tttgtaaagg atactttatc aatagaagca
     7021 ggtttgacag tacgtttctg tccctgtgcc ttcttcgcac ggatcgctgc gatcagggaa
     7081 cggatacgga ttcttgcagc accaaggtta tttacctcgt caatctttaa gcaggtatag
     7141 attttgtcac ttccgtcaag gatttcataa acctcgtcag tagtaactgc atccagacca
     7201 catccaaaag agttgagctg gatcagatcc aggtcatcgc gtgtctttac atagtttgca
     7261 gcagcataca gtctggagtg gtacatccac tggtcattga cgcggatcgg gcgttccaca
     7321 ggtgccagat gagagatgga atcctcagta agtacggcaa taccatagct gttgatcaga
     7381 tccgggatac catgatggat ttccgggtca atatggtatg ggcgtcctgc aaggacaata
     7441 ccatggcgtc ctgtatcttc cagatatttc agggtttctt cccctttttt ctgtacatcg
     7501 cggcgtgcag cagccatttc ctcccagccc ttatgcacag cagctttgac ttcttctgcc
     7561 gggatatcct taaattcctc taccagacga tttgccagaa tttcctcaga agtaaatgca
     7621 aggaacggat tgcggaaggt aatggacgga tcatttaatt cgtctacgtt attcttgata
     7681 ttttcggcat aagaggtaac aatcgggcag ttatagtgat tgactgcatc cggaaactcg
     7741 ttacgttcat atgggataca tgggtagaaa ataaatttca cgccattgcg gatcagccag
     7801 gttacatggc catgggcgag tttggcagga tagcattcag attcacttgg aatggactca
     7861 atacccagct cgtaaatctt tctggtggaa gtaggagaga gcacaacctc atacttcagt
     7921 tctgtaaaga aagtatacca gaaaggataa ttctcaaaca tgttcagaac acgggggata
     7981 cctactttac ctcgcgttgc cttatcagca gtaagcggtg tgtaggagaa aatacgctta
     8041 tatttatatt cataaagatt cggaatatga tctttgttct tttccttacc gataccgcgt
     8101 tcacagcggt taccgcttac atactggcgg ccgccggaga atttgttgat agtcagacgg
     8161 cagttattgg tacatccacg acagtttgcc atagaagttg tatatttcag ctcgttgatc
     8221 ttatcaatgg agagcatagt cgtttctgcg ccttcctgat ggcgttcacg ggcaatcagt
     8281 gcagcaccga aggcacccat gattccggcg atatccggac ggatggcttc gcagcctgca
     8341 atcttttcga agcttcgaag aaccgcatca ttgtagaagg taccaccctg tacaacgatg
     8401 tgcttgccaa gttcggaagc gtcagaaacc ttgataacct tatacagagc atttttgata
     8461 acagagtaag caagacctgc ggaaatatcg gaaacctcag ctccctcttt ctgcgcctgc
     8521 tttaccttgg aattcatgaa aacagtacat ctggtaccaa gatctatagg atgctgtgca
     8581 aaaacagcag cttttgcgaa atcctgtact gtataattca gggatttggc aaaggtttca
     8641 ataaaggaac cgcatccgga ggagcatgct tcatttaact gtacgctgtc aacggtcttg
     8701 ttgcggatct tgatacattt catatcctgt ccgccgatat ccaggataca gtctacctct
     8761 gggtcaaaga atgcagctgc atagtaatgg gatacggtct caacctcgcc ctcatccagg
     8821 agcagggccg ctttgagcag agcctcgccg taacctgtag aacaggaata agcgatcttt
     8881 gcgtctttgg gaagcagttc atagatttct ttaatagaac ggatggtagt ttttaacggg
     8941 tttccgttgt tgctactgta aaaggaatag agaagtgttc catcttcgcc taccagtgca
     9001 gttttggttg tggtggaacc tgcatcaata cccagatagc agtttccttt atatgtagcc
     9061 agatctcctg tttttacttt gtaggaactc tgacgttttg caaatgcatc gtattcttcc
     9121 tgagaagcga aaagtggttc catacgttct acttcaaaat ccagcttaat ggaattgcgg
     9181 agtctgtctt tcatttctgt cagggaaatg gagttgtctt ctttggcatt taatgcagaa
     9241 ccgatggctg caaaaagatg ggagttctcc ggaatgatgg tgtgttcccc atccagcttc
     9301 aaagtacgga taaaggattc tctcagttcg gacaggaagt gaagcggacc acccaggaat
     9361 gcaacatgtc cacggatggg ttttccgcag gcaagaccgg agatggtctg gtttacaact
     9421 gcctggaaaa tagaagctga cagatctggt ttggttgcac cgtcattgat cagcggctgg
     9481 atatccgttt tggcgaaaac accgcagcgt gcagcaatcg ggtagagcgc tttgtaatct
     9541 ttggcatatt cattcagacc tgtggcatct gtctggagaa gagaagccat ctggtcgatg
     9601 aaagaaccgg tgccacctgc acagataccg ttcatacgct gttctacgtt tccgttttcg
     9661 aaataaatga tcttggcatc ctcaccgcca agctcgatgg caacatctgt cttaggtgcc
     9721 agcttctgca gagaagtaga aactgcaata acctcctggg taaaaggaac gcccagatgg
     9781 ttggcaaggg tcagaccgcc ggaacctgtg atcacaggat ggagagtcat ctcgccatac
     9841 tggtcaaagg cctcctgaag aaggtctgca agggtttcct gaatgttcgc aaaatgacgc
     9901 ttgtaatccg cgaaaatgag attttcattc tcatctaaga tcgcgatctt tacagtagtg
     9961 gaaccaatgt caattccaag tgttttgtaa ttcataaagt aaattcaagc ctcctcgtat
    10021 tgtatataaa caaaattgaa attttcctgt tactgttcac acaccactat cccgcgaggt
    10081 gttttggcat gaatatgcca aaatcccgag acatacaagc caaaattcca ttgccacagg
    10141 caatctggaa tgaattttgg ctacgttact gagaacggag tgaacagtaa cattttcctt
    10201 actgtttgct gctgatatca tgcaaagcgt gttgccggac acgaagtaaa cagtaaaaat
    10261 ctatcctgtt ctttcctatt aaatatctgt ttccagatat ggaatattcc gtaatattat
    10321 acgctaatgg tctggaaaag acaatatgaa agtttaccaa tgattacctt atttgcagtt
    10381 gaaaattcag ctatttcggg atataataga aaaagtgatt tttatcaaga ggagagaaaa
    10441 aatggcagaa tataaacttc ttaaaacaga aggccgtgcc aagcgtgcag agtttcatac
    10501 agtgcatggt acgatccaga ctcctgtttt tatgaatgtg ggaacgatcg gtgcgattaa
    10561 aggcgctgta tccaccatgg atttacagca gatcggaaca caggtagaat tatcaaatac
    10621 ttatcatctt catgtgcgtc cgggtgataa aatagtaaag cagttaggcg gccttcataa
    10681 atttatggta tgggacaaac caatccttac agactcaggc ggattccagg tattttccct
    10741 tgcaaagctg agaaagatca aagaagaggg ggtttatttt aattcccata ttgacgggca
    10801 taagatcttt atgggaccgg aagagagtat gcagatccaa tccaatcttg cctccaccat
    10861 tgccatggca tttgatgaat gtcccagcag tgtggctgac agggattatg tgcagaaatc
    10921 tgtagacagg accacaagat ggcttgcccg ctgtaaagcg gaaatggcga gactgaacag
    10981 tctgccggat accattaaca aagaacagct tctgtttgga atcaaccagg gtgctgttta
    11041 tgaagatatc cgcattgagc atgccaaagc gatctctgaa atggatctgg atggctatgc
    11101 tgtcggcggt ctggcagttg gagaaaccca tgaagagatg tacaggatcc tggatgcggt
    11161 agtcccttat cttcctcaga acaaacctac ttacctgatg ggcgtgggaa caccggcaaa
    11221 tatcctggaa ggtgttgaac gtggaattga tttctttgac tgcgtatatc caagccgtaa
    11281 cggccgccat ggacatgtat ataccaatca tggaaagatg aatctgttca atgcaaaata
    11341 tgaactggac acacgtccta tcgaagaagg ctgccagtgt cctgcatgcc agcattacag
    11401 cagagcctat atccgtcatc ttctgaaagc aaaggaaatg ctgggaatgc gtctctgtgt
    11461 acttcacaat ctgtatttct ataatcatat gatggaagag atccgtgatg ctcttgatgc
    11521 aggaaacttc gcagaatata agaaaatgcg gctggaaggc tttgaagagg gcaaaataaa
    11581 ctcgaaaaga taatctgtat ataaaataat tattaaatat gccaaaaact cttgaagtaa
    11641 agcgtttttt tgtgtatgat gtgtagtgac gctttaatca gattgttctg catgaaaaca
    11701 agatttcata cagaaggtaa cggagattat aagtggatcg caaagcagct cttcagtatg
    11761 agcagccgtc aggacggtct gtgaatacat gatggactgc aaatatgcag aataacagga
    11821 aaagttacag gaggaatcaa aatgaacgca tcaagcggaa tgggtatggt tggcgctatt
    11881 gtctggatgg tagtactgtt cggaattatg tacttcttaa tgcttcgccc tcagaaaaaa
    11941 gagcagaaga gacttcaggc aatgttaaat gacatggagg ttggcgacag cattgttact
    12001 accggcggct tttatggagt tgtcattgat atgacagaag aagacgtgat cgtagaattc
    12061 ggtaataaca aaaactgccg tattccaatg agaaaacagg caatcgctga agttgagaaa
    12121 gccggaagcg ctgccgaata atgaaagaga tatgaaaaaa gcggaaccta tagtcagtga
    12181 tggctgtggt tctgtttttt tatttttaca gtaaaatctc tggaaaacag cacttttgta
    12241 ttttttcact ttaataggtt gaaatctgtc ggaaagtgcg ttattataat aacaattacg
    12301 caattagagt atttttggag gaaattatta tggattataa gattgcattg atccccggcg
    12361 acggaatcgg accggaaatc gtaagagaag caaagaaagt actggacaag gtatgcgaga
    12421 aatatggaca cagcttttcc tattcagaag ttctgttagg cggcgcatcc atcgatgtac
    12481 acggcgtacc ccttactgat gaggcaattg ccactgccaa atcatcagac gccgtactga
    12541 tgggctctat tggcggagat gcaaaaactt ctccatggta taagcttgag ccgtccaaac
    12601 gcccggaagc aggacttctt gcaatccgta aggcattaaa tctttttgca aacttaagac
    12661 cggcttacct ttacaatgag ctgagaaaag cctgccctct ccgcgatgag atcatcggag
    12721 acggatttga catgatcatt gtacgtgagc ttacaggtgg cctgtatttc ggagaacgtc
    12781 agactattga agagaatggt gtgaagaaag cgattgatac actttcctat aatgaaaacg
    12841 aaatccgccg tattgccatc aaagcatttg agatcgcacg taagagaaga aataaagtaa
    12901 caagcgtaga taaggcaaat gttctggatt cttccagact ctggagaaaa gtggtagagg
    12961 aagttgccaa agactatccg gatgttacct tagagcatat gctggttgac aactgcgcaa
    13021 tgcagcttgt acgtgatcca aaacagttcg atgttatcct gacagagaat atgttcggag
    13081 atatcctttc agacgaggca agtatggtaa caggctccat cggaatgctt tcatctgcaa
    13141 gcttaaatga gacaaaattc ggtctctatg agccaagcca tggttctgca cctgatattg
    13201 caggacagga taaggcaaac cctatcgcaa ctatcctttc cgcagcaatg atgcttcgct
    13261 tctcccttga tatggacaag gaagcagatg cagtggaagc agcagtgcag aaagtcctga
    13321 cagagggata ccgcacaggt gatatcatgt cagagggatg caagcttgta ggaacaaagg
    13381 aaatgggcga tctgatcgca gcagctctgt aagaattgat attaagagga ttcagccggc
    13441 gcaggcagat tacggagtca ggaatttcgg ttgaatcatt aaaaataaat aaaacagtaa
    13501 gaaaagagga aataaaacaa tgagaagtga tgcagtaaaa acaggcacac agcaggcacc
    13561 tcaccgttcc ctgtttaatg ctcttggaat gacaaaagaa gaaatggaca gacctctggt
    13621 aggtatcgta agttcttaca atgaaatcgt accgggtcat atgaaccttg acaagatcac
    13681 acaggcagtt aagcttggtg tggcaatggc aggcggtaca cctgttatgt tcccggcaat
    13741 cgcagtatgt gacggtattg caatgggaca cgttggaatg aaatattctc tggtcaccag
    13801 agacctgatc gcagattcca cagaagcaat ggcaatggca catcagtttg atgcactggt
    13861 aatgattcca aactgtgaca agaacgtacc cggacttctg atggcagcag ccagactgaa
    13921 tgttcctact gtatttgtaa gcggcggtcc aatgcttgcc ggacatctga acggacacaa
    13981 gacaagtctt tccagtatgt tcgaggcagt aggtgcttac gcagcaggca agcttgatga
    14041 ggacggactg acagaatgtg aaatgaaaac atgtcctaca tgcggatcct gttccggtat
    14101 gtacacagca aactccatga actgtctgac agaggttctt ggtatgggtc tgaaaggaaa
    14161 cggaactatt cctgctgtat attccgaacg tatccgtctt gcaaaacatg caggtatgca
    14221 ggttatggaa atgtacagaa agaacatccg tccaagagat atcatgacaa aagaagcaat
    14281 cctcaatgcc ctgacagtag acatggcac
//
