LOCUS       c00041_gnlPro..        15414 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HFLFJKGA_41.
ACCESSION   c00041_gnlPro..
VERSION     c00041_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 23:36:21
            Original ID  :: gnl|Prokka|HFLFJKGA_41
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 11692
            Orig. end    :: 27106
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15414
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[21692:24707]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13015
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..15414
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15414
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(535..1413)
                     /locus_tag="ctg41_15"
                     /transl_table=11
                     /translation="MIVVYLIFLAVIQAVTEFLPVSSLGHLCILEQYMGIGHETGLLSE
                     TMLHLGSAAAIIFLFRKDLKKIGLGLLGMFMDMIGNLNLYIHNKKTGESLGYARIVTGT
                     YRKTGALLVISMIPTALLGLTGKRLALLAADSQIVPGIGFLLTGVFLLVTDLNKSGGKK
                     GPREASYDSAMWIGICQGIAVFPGISRMGFTLCAALLCGYNRKFAVRFSVFMSLPAIIG
                     AFFTEIGNFGASEMTAGLGFTYVFAMIIAGFAGCLVVRNTIAMTQNIKLRYFAYYSFIV
                     GIITLALNFAL"
     CDS             complement(1570..1710)
                     /locus_tag="ctg41_16"
                     /transl_table=11
                     /translation="MKKKKSSRKMNEFWLLLFTGNIPRGVFCERRSQKTRDILREFMRL
                     A"
     CDS             complement(1676..2572)
                     /locus_tag="ctg41_17"
                     /transl_table=11
                     /translation="MKKKNKTRSVTGLLFGFMERVSGDHVGAYATQAAYFLIMSFIPCI
                     LFLTTLVRYTPLTYNVVRDAIVAFIPENLQSFVLGIVVDVYKRSTAIVPLSAIVALWSA
                     GKGMQSIINGLNTIYHVKETRNWLLTRIYAVFYTLSLVIAVIVSLLMLVLGNEIQKVVS
                     RYIPFLGRVLGKILGARALLVFGVLFLVFLMLYKVLPNRKATFKSQIPGALIIAVAWSI
                     FSYGFSFYFEIFPGFSNMYGNLATIIMVMVWLYICMNLLLYGAEINAYFEKEFRIAHKS
                     VQELLAHEKEKKQQENE"
     CDS             complement(2804..3865)
                     /locus_tag="ctg41_18"
                     /transl_table=11
                     /translation="MSVSERKFGILQTGETVKIFHLENKSGAYAEVTDFGAILVKVCVP
                     DKDGTLTDVVLGYDDLASYEVNGCFFGSTIGRNGNRIGGAKFSVNGKEVVLAQNENDNN
                     LHSGPDGFEKKLWKVAEISDDKNSVIFNRISPDGENGFPGEFDVSVKYEFTEDNELRIH
                     YQGICDEPTVANMTNHSYFNLNGEGSGTAMDQYLTIHAKYYTPVADSHSIPTGVYGEVA
                     GTPMDFRTAKKIGQDIEAEFDQLKFTGGYDHNYVTDNYAKGNRRLIATAYSDKTGIAMD
                     VTSDCPCVQFYAANFVENEHGKNGHTYNKRDAFCLETQVEPNAVNVEDFHSPILNAGEQ
                     YDSVTAYHFYIIK"
     CDS             complement(3862..4047)
                     /locus_tag="ctg41_19"
                     /transl_table=11
                     /translation="MSGRHYAAEDRRSVEDTHLAAARRQWEGNGISGTVKMSRREALFY
                     YLLDLILFYDTGGWKQ"
     CDS             complement(4218..5708)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg41_20"
                     /sec_met_domain="PALP (E-value: 1.5e-17, bitscore: 54.7,
                     seeds: 146, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQVLYKSTRGKEETVTASMAILKGLSEDGGLFVPTEIPKLDVPMD
                     ELAKMSYQETAYEVMKCFLTDFTEEELKNCINNAYDEKFDTKEIAPLHEADGAYFLELY
                     HGATIAFKDMALSILPHLMTTAAKKNQVKNEIVILTATSGDTGKAAMAGFADVPGTKII
                     VFYPKHGVSPIQEKQMVTQKGNNTYVVGITGNFDDAQTAVKKMFNDKELEAELDAAGYQ
                     FSSANSINIGRLVPQIVYYVYAYASLVRQGKIKDGQEINVVVPTGNFGNILAAYYAKQM
                     GLPVHKLICASNDNKVLYDFFRTGTYDRKRDFILTTSPSMDILISSNLERLIYRIAGGD
                     AKKCAELMQSLTAGGEYTITEDMKAQLADFYGNYCTEDETAKTIAEIFKDSHYVIDTHT
                     AVAAGVYDKYVKDTNDTTPTVIASTASPYKFTRSVMEALGADTDGKDDFALADELSALS
                     GVKLPQAVETIRTAPVLHNRVVDAPDMPKAVKDILGIR"
     CDS             complement(5663..5812)
                     /locus_tag="ctg41_21"
                     /transl_table=11
                     /translation="MCSIGEMNNCNCSAVYYYCQYTEQLRITLERQEISCRYYTKAQEE
                     KKKP"
     CDS             complement(5992..6828)
                     /locus_tag="ctg41_22"
                     /transl_table=11
                     /translation="MKVQKKESKQSGNPARSLILVTVCTCTAIAFAAGGRIADFNGKNK
                     VYAASENREKTFSSDADETDVLPTGIAGVVSGMNDTASPKKSVTRIGTSCEQVMVGQRI
                     KVIEDNMAEFDVSSSMESSINELDARTAALAESARMMSDEDYDTLLHIVEAEAGTEDVK
                     GRILVANVIMNRIKNKEFPDTVTEVVWQNTNGVPQFSPTYDGRINEVTVTDETREAVRQ
                     ALEGVDYSEGALFFIQKSEAESQNVSWFEKDLKRLFKYGVHEFYTYPDSAESSTGS"
     CDS             complement(7024..9573)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AstE_AspA"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg41_23"
                     /sec_met_domain="AstE_AspA (E-value: 9.8e-33, bitscore:
                     104.2, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIINCVHGGWHKVKDLLSEIESYWTTRAEGYSEVNHKELNGMQKG
                     AWLEVLKGQFPEKAKDEIKILDIGTGPGFFPVILAEAGYKVTAVDYTQEMLDTAKRNAG
                     NLCERISFYKMDAQNLEFEDDVFDVVISRNLTWNLKDPKRAYEEWCRVLKPGGKLLNFD
                     ANWYGYLYDEEKRLSYEEDRKSVESEHLDDHYLCTDIDRMEKIALQMPLSSINRPSWDR
                     KFLKENGFESVAVDTGIWQRVWSQEEKLNYHSTPMFMISAVKEEKNVWSENDGMGDSDS
                     GYDRKRDLEDAMLCAAPGMKKNGFLRLGGGEFSLPYTVICGSHPGKTVLITAAVHGGEY
                     VGIQAAVELADKLKPEKIHGRVILVKTVCRKEFEERSGSVCPEDEKNLNRVFPGNPQGT
                     RMDRLAYEVVQKLHSAADYYIDLHSGDDYEQLTPYIYYAGCADENVVQMSRKMAEQADV
                     PYMVKSNVASGGSYNYAAACGIPSVLIERGQMGGWSPEEVHSTRKDVRNILCALGVYDG
                     MRSYSNYYPMEIEDVRYQSASVSGLWYPAKKPGDIIKVGEYLGCVKDYERNILETSLSD
                     LNGVVLYQTGSLQVIKDGPMIAYGSFSRRKDERKKKITNYWAKRSDSFMEQRRAELHSD
                     MADKWLKEIGTFLPDGKLRILDVGCGAGFFSILLAKLGHEVTGIDLTPDMIIHSRELAK
                     EENASCTFEVMDAENPDFPDGTFDVIVSRNLTWTLPDAARAYKEWIRVLKTGGILINAD
                     ANYGADDFSDTADLPANHAHFTVGDAMMQECEEIKRQLPISSYVRPAWDLETLGKLGIN
                     RFSIDLGISSRIYTKKDEFYNPTPMFLICGEKNKCNN"
     CDS             complement(10001..10756)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 83.9;
                     E-value: 4.1e-26)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg41_24"
                     /sec_met_domain="Radical_SAM (E-value: 1.8e-27, bitscore:
                     87.6, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDDDIMDNKQIKGYVHSLESFGSVDGPGVRYVIFLSGCAMRCQFC
                     HNPDTWKMKQGELYTADELLKKALRYKGYWGSKGGITVSGGEPLLQMDFLTEFFKKAKA
                     EGVHTNLDTSGNPFTDQEPWHSGWLELMKYTDLVMLDIKQIDEQEHIKLTGHSNKNILA
                     MARELSDMKKPVWIRHVLVPDGSDKDEYLHRLADFIHTLSNVERVEVLPYHTLGKFKWE
                     NLGLSYPLEGVNPPTQERIDNARKILGAI"
     CDS             complement(10760..13015)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg41_25"
                     /sec_met_domain="Gly_radical (E-value: 2.2e-41, bitscore:
                     131.6, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 4.5e-268, bitscore:
                     881.3, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNFEQWNGFKGNRWKEKIDVRNFIGMNYTPYDGDASFLEGPTEA
                     TNKLWGKLQALQKEERAKGGVLDMETEVVTSLTAYGPGYIDEETKDLEKVVGLQTDKPL
                     KRAFMPYGGIKMAEQACETYGYKVSDKIKDVFHNYEFKTHNQGVFDIYTPEMKVARHNK
                     ILTGLPDTYGRGRIVGDYRRVALYGIDALIEGKQKDFAACDRQGMRRYDFQLREEIADQ
                     IRALKGMKVMAESYGYDISKPAKDAREAFQWLYFGYLAAIKTQNGAAMSVGRISTFLDI
                     YIERDLQNGTLTEKEAQELVDHMVMKFRMVKFARIPSYNQLFSGDPVWATLEVAGMGQD
                     GRSMVTKNDYRFLHTLEDMGPAPEPNLTVLYSSRLPENFKKYAANISVTTSSVQYENDD
                     VMRPVWGDDYSICCCVSATETGKEMQFFGARANLAKCLLYAINGGVDEKTKQQVGPNYQ
                     PITSEYLDYDEVIAKYDKMMDWLAHLYVGTLNMIHYMHDKYYYEAAEMALIDTKVERSF
                     ATGIAGFSHVVDSLSAIKYAKVKAIRDEDGITTDFQVEGDFPRYGNDDDRADEIATTLL
                     STFLEKLKHIHTYRDSKPTTSILTITSNVVYGKATGSLPDGRKAGEPLAPGANPSYGAE
                     QNGLLASLNSVAKLDYEDALDGISNTQTINPDALGHSDDERSENLVHVLDGYFDQGAHH
                     LNVNVFGKEKLIDAMEHPEKEEYANFTIRVSGYAVKFIDLTREQQLDVIARTCHDRM"
     CDS             complement(13422..15155)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HMGL-like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg41_26"
                     /sec_met_domain="HMGL-like (E-value: 5.6e-76, bitscore:
                     246.3, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEDFFMSFYSQSPQSKHNIYITEEEKMMNPSKYQRQYFMPPVKCM
                     KWAEKEYVDKAPVWCSVDLRDGNQALVIPMSLEQKIEFFKLLVKIGFKEIEVGFPAASE
                     TEYEFLRTLIEQHLIPQDVTIQVLTQAREHIIRKTFEAVKGAPKAIVHVYNSTSVAQRE
                     QVFKKSKEEILKIAVDGAALLKKLADETEGNFQFEYSPESFTGTEPEYALEVCNAVLDV
                     WQPTADNKCIINLPVTVQHSMPHVYASQVEYMCENLKYRENVIVSLHPHNDRGCGVADS
                     EMGLLAGADRIEGTLFGNGERTGNVDIVTLGMNMYSQGVDPKLDFSDMPHICEIYEECT
                     GMKVGERSPYSGALVFAAFSGSHQDAIAKGMHWRDDKDPDHWNVPYLPIDPTDVGRNYD
                     ADVIRINSQSGKGGVGYILETKFGLNLPPKMREAMGYATKAVSDHKHKELHPDEIFNLF
                     KQTFENITEPYSINEVHFQQKDGGIITKVTSTFRGKTITTEASGNGRLDAVSNALKKAY
                     ELKYSLETYQEHALERSSSSKAIAYVGIKKPDGTLAWGAGVDADIIRASIDALVTAINN
                     R"
     CDS             complement(15310..15414)
                     /locus_tag="ctg41_27"
                     /transl_table=11
                     /translation="STLGPEHRELLVAEKQWKEIVELAFEQLPEIIQE"
ORIGIN
        1 aatgatcaca tatccgccga tagttccaaa agcagatgtg acagaaatac agatcgctcc
       61 tccgatcaga ccaccgcctg ttttataatc tgcgcttaaa gcataataat ccagcaaagt
      121 tgtactctgc atatatccgt ctgtgagaag ctgcgctgcc ccacacagaa acagaaacat
      181 cacaaacgcc gctgcaagtt tcttatatgc cagccggttt gttttattga tcagaataaa
      241 tgctgattca aggaaaaata cgattggaaa cagatatgcc atcagtccca tcagtccgaa
      301 acagaaatta ctgatcgcat ctcccacaaa accacctgct ccaaaattgc ttgccatcag
      361 gatcacacat gcggccaaaa tcacaaataa tatgatttct gtctgaaatc tgccgacttc
      421 ctgttccatt gctgtcttct tttttgtatt tcttcccgaa tgcccggtat tcttactctt
      481 tgatgctgcc attctaaggc tcccctcctt gatcttctcg taaatatctt ccctttacag
      541 ggcaaaattt aatgccagtg taataatacc gactataaat gaataatatg caaaatagcg
      601 taattttata ttctgagtca tggctattgt atttcggaca acaagacatc ccgcaaaacc
      661 ggcgatgatc attgcaaata cataggtaaa cccaagtcct gccgtcattt cagaagcacc
      721 aaaatttccg atttccgtaa aaaaagcacc tatgatagca ggcagactca taaaaacaga
      781 aaaacgaacc gcaaatttgc ggttatatcc gcataacagt gcagcacata acgtaaatcc
      841 cattctggaa atccccggaa agacagcaat cccctgacaa attccaatcc acatggcgct
      901 gtcataagaa gcctctctcg gtcccttttt tccaccggat ttattcagat ctgttaccag
      961 aagaaatacg cctgtaagta aaaatccgat tcccggaaca atctgagagt ctgcggccag
     1021 aagagccagc cgttttcctg taagtcccag aagtgctgtt ggaatcatgg aaatcacaag
     1081 aagtgcacct gttttccgat atgttccggt gactattctg gcatagccca aactttcccc
     1141 tgtcttcttg ttatggatat atagattcag attaccgatc atatccataa acatccccag
     1201 aagtcccagt ccgatttttt ttaaatcttt gcggaacaaa aatataattg ctgccgcact
     1261 tccaagatgg agcatcgttt ctgacagcaa tccggtttcg tggccgattc ccatatattg
     1321 ttccaatatg cataaatgtc ccaggctgct gacaggaaga aattccgtca cagcctgaat
     1381 gacagccaaa aatatcaaat atacaacgat catagaactg attccttttt gtttctccaa
     1441 aattatggtt tattatagca cactcagaaa ggctttacaa taaaaagccc cctgactgtc
     1501 atgttcacaa cgtagccaaa agttactgtt cactccgttc ccagcaacac gcttcgcgat
     1561 gcacagaatt tatgctaatc gcataaattc gcgcagtatg tctcgggttt tctgtgacct
     1621 tcgctcacaa aaaacacctc gcgggatatt accagtgaac agtaacagcc agaattcatt
     1681 cattttcctg ctgctttttt tctttttcat gtgccagcag ttcctgtacc gatttatgtg
     1741 caatccggaa ttctttttca aaataagcat tgatctctgc accgtataac agaagattca
     1801 tacagatata caaccatacc atgaccatga tgatcgtcgc aaggtttccg tacatattac
     1861 tgaatcccgg aaaaatctca aaataaaaag agaatccgta tgaaaatatc gaccatgcaa
     1921 ctgctatgat caaggctccg ggaatctggc ttttgaatgt ggcttttctg ttcggaagaa
     1981 ccttatacaa cataagaaaa accagaaaca acacaccaaa taccaacagt gctcttgccc
     2041 ccagtatttt tcccagaact cttccaagaa aaggaatata tcttgataca actttctgta
     2101 tttcgtttcc gagtacaagc ataagcagag acacgattac cgcaatcacc agtgataaag
     2161 tatagaatac tgcataaatt ctggttaaca gccagttacg ggtttctttt acgtgataaa
     2221 tggtatttaa tccattgatg atagactgca ttccttttcc ggcagaccac agtgccacaa
     2281 ttgctgacaa agggacaatt gcagtacttc ttttgtatac atctaccacg atccccagaa
     2341 caaaactctg cagattctcc ggaataaaag caacgatcgc atccctgact acattatagg
     2401 tcagaggtgt ataccgtacc agtgtagtca gaaacagaat gcagggaata aaagacatga
     2461 tcagaaaata cgctgcctgt gtcgcataag ctcctacgtg atctccggat acacgttcca
     2521 taaacccgaa taaaagccct gtaacagacc gggttttatt tttctttttc atatatgtct
     2581 ccattctgtt attttacagc agtcatttct gataatgcat ttatggtgat tgctgtaatt
     2641 ataaagataa ctgtttcgaa tatctctgtt tactatcata ccatgaaact gccgttatga
     2701 caaacatgaa ttatggataa taaaatccgg ttcttttcat gctggaatgc tgtagatatg
     2761 aaaaaaaccg gatcaatatg taattagttt tatggtcaga tttttacttt atgatgtaga
     2821 aatgataagc agtcacagaa tcatactgtt cacctgcatt aagaatcggg gagtggaaat
     2881 cttcaacatt gaccgcattc ggttcaacct gcgtttccag acagaaagca tcccgcttat
     2941 tgtaagtatg accattttta ccatgttcat tttcgacaaa atttgctgcg taaaactgta
     3001 cacatggaca gtcagaagtg acatccatgg caattccggt tttatcactg tatgcggttg
     3061 cgatcagtct tctgtttcct tttgcataat tgtctgtcac ataattgtgg tcatatccgc
     3121 ctgtgaattt cagctggtca aattctgctt caatatcctg cccgatcttt ttggcagttc
     3181 tgaaatccat gggagtccct gcaacttccc catacactcc tgtaggaatg gaatgactgt
     3241 cggctacagg tgtataatat tttgcatgga ttgtaagata ctgatccatg gcggttccgc
     3301 ttccctcacc attcagattg aaataagaat gatttgtcat attggcaact gtcggttcat
     3361 cgcagattcc ctgataatgg atcctcagtt cgttgtcttc cgtaaactca tattttacag
     3421 acacatcaaa ttctcccggg aaaccattct cgccatccgg acttatacgg ttaaatataa
     3481 cactgttttt atcatcggaa atctcagcca ctttccagag ctttttttca aatccgtcag
     3541 gaccgctgtg aagattattg tcattctcat tctgagcaag aactacttct ttgccattga
     3601 cagagaattt cgcaccgccg atgcggtttc cgtttctgcc gatggttgaa ccgaaaaagc
     3661 atccatttac ttcataagat gccagatcat catatccaag tactacgtct gttaaagtac
     3721 catctttatc aggtacgcag accttaacca ggattgctcc aaaatctgtc acttccgcat
     3781 atgccccgga tttgttttcc agatgaaaaa tttttactgt ttccccagtc tgtaatatgc
     3841 cgaactttct ttcagaaaca ctcattgttt ccaacctccc gtatcataaa ataatattaa
     3901 atccaaaaga taataaaaaa gagcctctct acggctcatt tttacagttc ccgaaatgcc
     3961 gttcccttcc cattgacgcc tagccgcagc taggtgggta tcctcaacag accttctgtc
     4021 ttccgctgca taatgacggc ctgacatccg gcctgcgatg ttgggttccc gttaaagtcg
     4081 atgtaggttc aaaaaaagaa ggggcctcgt acatttcagg atattcactg tttttaactg
     4141 atttttatta tactccagta tatgttcttt ttcaacataa aatgtagaat taattatatt
     4201 tttttataat atggagatta tcggattcca aggatatctt ttactgcctt tggcatatcc
     4261 ggcgcatcta ccacccggtt atgaagtacc ggtgctgtgc ggatcgtctc aactgcctgt
     4321 ggaagtttca ctccggaaag cgcactcagt tcatcagcca gtgcaaaatc atccttaccg
     4381 tctgtatctg ctccaagtgc ttccattaca cttcttgtaa atttatatgg gcttgctgtg
     4441 gatgcaatga cagttggtgt ggtatcattg gtatctttta catatttgtc ataaacacct
     4501 gctgcaactg cagtatgggt atctatcaca taatgactgt ctttgaagat ttctgcgatt
     4561 gtttttgctg tttcgtcttc tgtacagtaa ttgccataga agtctgcaag ctgtgccttc
     4621 atgtcttctg tgatggtata ctcgccgcca gcagtaagag actgcatcag ctctgcacat
     4681 ttttttgcat caccgcctgc gatacggtag atcagacgtt ccagattgct ggagatcaga
     4741 atatccatgg acggtgaggt tgtaaggata aagtcacgct ttctgtcata agttcctgtg
     4801 cggaagaaat catacagaac cttgttatca ttggaggcac agataagttt gtgaaccgga
     4861 agtcccatct gttttgcata ataagcagcc aggatatttc caaagtttcc ggtaggtact
     4921 accacattga tctcctgacc gtctttgatc ttgccctgac gtacaagtga tgcatatgca
     4981 tatacataat aaacaatctg cggtaccaga cgtccaatat tgatagagtt cgcagatgag
     5041 aactgatatc ctgcagcatc aagttctgct tccagttcct tatcattgaa cattttcttt
     5101 acggcagtct gtgcatcgtc aaagtttccg gtaattccca caacatatgt attgttgcct
     5161 ttctgagtta ccatctgttt ctcctggata ggacttacac catgtttcgg atagaaaacg
     5221 atgatcttgg ttcccggaac atctgcaaat ccggccattg ccgctttacc tgtatctccg
     5281 gaagtagcgg taagaataac aatctcattt tttacctgat tcttcttagc agctgtagtc
     5341 ataagatgtg gaagaattga taatgccata tccttaaacg caatggtcgc accatgatac
     5401 agctcaagga aataagctcc gtctgcttca tgaagcggtg caatctcttt tgtatcaaat
     5461 ttttcatcat aggcattgtt gatgcagttc tttaattctt cttctgtaaa atcagtaagg
     5521 aaacatttca ttacttcata tgctgtctcc tgatagctca tctttgccag ctcatccatt
     5581 gggacatcca gcttcggaat ctctgtcggc acaaataagc cgccatcctc agaaagcccc
     5641 tttaaaatag ccatagaagc tgttacggtt tcttcttttc ctcttgtgct tttgtataat
     5701 acctgcatga tatttcctgc ctttccaaag ttattcgtaa ctgttcagta tattggcagt
     5761 aataataaac cgctgaacag ttacagttat tcatttcgcc aattgagcac attatagcat
     5821 atactttagc aaaatactat cctaaattat ttctcttttt tctgtctttt tatgattgat
     5881 tactataaat caaaaatatg gacatattct tttgttcccg aagaatatgt ccatattttg
     5941 agcagtatta ccgcaatcct gttaaatgag ttatatgaag agtatcgttt attacgatcc
     6001 tgtggaactt tctgctgaat ccggataggt ataaaattca tgtacgccgt atttaaacag
     6061 ccttttcaga tctttctcaa accaggagac attctggctt tcagcttcag acttctggat
     6121 aaaaaacagt gctccttctg aataatccac accttcaaga gcctgtctga cggcttctct
     6181 tgtctcatct gtaacagtta cttcattgat acgtccgtca taagtcggcg aaaactgcgg
     6241 aacaccattg gtattctgcc ataccacttc tgtgactgta tcgggaaatt ccttattctt
     6301 tatacggttc atgatcacat tggcaaccag aatgcgtccc ttgacatcct cagtacctgc
     6361 ttcagcttct acaatatgaa gcaatgtatc atagtcctca tccgacatca tccgggcact
     6421 ctctgcaaga gccgctgtcc ttgcatctaa ctcattgatg ctgctctcca tagaagagct
     6481 gacatcgaat tctgccatat tatcttcaat aactttgatt ctctgaccga ccattacctg
     6541 ttcacaggaa gttccgatac gtgtgactga ttttttggga gaagctgtat cattcattcc
     6601 agatactact cctgcaattc ctgttggcag tacatctgtt tcgtcagcat cagaggaaaa
     6661 agttttctcc ctattttcag aagctgcata tactttgttt tttccattaa aatctgctat
     6721 tctgccgcct gctgcaaacg caatcgccgt acaggtacac actgtaacca gtatcagact
     6781 ccgcgccgga ttgccggact gttttgactc ttttttctga actttcatac ttatcattcc
     6841 ttgagttttt ttaattacag gtttttatgg ttgtaacatt tctgtaactt ataagaaaat
     6901 tatatttaat ataattgatt ttgtcaagct tttttcatat ttttgtaaca ttttagcttg
     6961 caaaaaagaa aaaaaggaag gctccatcaa tgaaatctcc ctttaatata tgcttcattt
     7021 ttctcaatta ttacatttat ttttttcgcc gcagatcagg aacatagggg ttggattata
     7081 aaactcatct ttctttgtat aaattctgct gctgataccc agatcaatgg agaatctgtt
     7141 gatacccagt tttcccagtg tctccagatc ccaggcaggg cgtacatagg aactgatagg
     7201 aagctgacgt ttaatttcct cgcattcctg catcatggca tcgcctactg taaaatgagc
     7261 atgattggca ggcaaatcag cagtatctga gaaatcatct gcaccataat tggcatctgc
     7321 gttgatcagg attcctcccg ttttcagcac acgaatccat tctttatatg ctcttgctgc
     7381 atccggaagt gtccaggtaa gatttctgga cacgatcaca tcaaaggtac catcaggaaa
     7441 atccggattt tccgcatcca ttacttcaaa cgtacaggag gcgttctctt cttttgccag
     7501 ttccctggaa tgaatgatca tatccggtgt cagatcgatt cctgtaactt catgtcccag
     7561 ttttgctaaa agaatggaaa agaagcctgc accgcatccc acatccagaa tccttaattt
     7621 tccatcagga agaaaagtcc cgatctcttt cagccattta tcagccatat cactgtgaag
     7681 ctcagctctt ctctgttcca taaaactgtc gcttcttttc gcccagtaat ttgtgatctt
     7741 tttcttgcgt tcatcctttc ttctgctgaa actgccatat gcgatcatcg gaccatcctt
     7801 aataacctga agacttcccg tctgatatag aaccactcca tttaaatcgg ataaacttgt
     7861 ctccagaata tttctctcat aatccttaac acagccaaga tactctccaa ccttaatgat
     7921 atctcccggt tttttggcag gataccacag cccggataca ctggcagact gataacgcac
     7981 atcttcaatt tccatgggat aataattact gtaacttctc atgccatcgt aaacacccag
     8041 cgcacacaga atattacgca catcttttct tgtagaatga acctcctccg gactccagcc
     8101 tcccatctgg ccacgttcga tcagaacact gggaatgcca catgcggcag cataattgta
     8161 agaaccaccg gatgccacat tagactttac catataggga acatctgcct gctctgccat
     8221 cttccttgac atctgaacca cattttcatc tgcacatccg gcatagtaaa tataaggcgt
     8281 aagctgctca taatcatccc cgctgtgaag atcaatataa taatctgctg cactgtgaag
     8341 cttctgaacc acctcatacg ccagacggtc catcctggtt ccctgcggat tccccggaaa
     8401 tacacgattc agattcttct catcctccgg gcagacactg ccgctcctct cctcaaattc
     8461 cttcctgcac acagtcttaa ccaagattac tcttccatgg atcttctcag gcttcagttt
     8521 atctgcaagc tcaacagcag cctggattcc cacatattct cctccatgga ccgcagcggt
     8581 gattagaact gtctttccgg gatgagaacc gcagattact gtataaggaa gcgaaaactc
     8641 acctccgccc agtctcagaa atccattctt tttcataccc ggagcagcac acagcatggc
     8701 atcctccaaa tctcttttcc tgtcatatcc gctatcagaa tcacccattc catcattctc
     8761 ggaccagacg tttttctctt ccttcacagc gctgatcata aacatcggcg tagaatgata
     8821 attcagcttc tcttcctgac tccacacccg ctgccagatt ccggtatcca ctgccacaga
     8881 ttcaaacccg ttctccttca gaaacttcct gtcccaggac ggtctgttaa tagaagaaag
     8941 aggcatctgc agtgcaatct tctccattct gtcaatatcc gtacagaggt aatgatcatc
     9001 cagatgctca ctctccacac tctttcggtc ttcctcataa gacaggcgtt tctcctcatc
     9061 ataaagataa ccgtaccagt ttgcatcgaa attaagaagc tttccgcccg gtttcagtac
     9121 acgacaccac tcttcataag ctctcttagg atccttcaga ttccatgtca gattcctgct
     9181 gatcacaaca tcaaacacat catcctcaaa ttccagattc tgagcatcca tcttataaaa
     9241 agaaatccgc tcacaaagat taccggcatt cctcttcgcg gtatccaaca tctcctgcgt
     9301 ataatcaaca gcagtcacct tatatcccgc ctcagccaga ataacaggaa aaaatccagg
     9361 tcctgttccg atatccaaaa tcttaatctc atccttcgct ttctccggga actgcccttt
     9421 caacacctca agccatgccc ccttctgcat cccattcaat tccttatgat taacttcaga
     9481 atacccctca gcccgggtag tccagtaact ctcaatctcc gataataaat ccttcacctt
     9541 atgccaacct ccatgcacgc aatttataat catatatagc caaaattata tcaaatccct
     9601 cccctttcca acaagccctc ccgggggata tatttcacat ctcaattcat ttttgcataa
     9661 acaaagtcct tcttaaaact ttttcacact tcgccttgta tttatatatt aaccaaaacc
     9721 agcgaagcag gcgtatagtt gtaccggatg catttgcagg catcttagag attcttagtc
     9781 ctcggaaatc tgcgttatga gacgaaaagt cccttgtctg agcgacagcg agtaattccg
     9841 gacttttcgt ctcatgcttt tagcggattt tcgagggctt agaatctctt agatgccgaa
     9901 accgtatccg gtacaactat acgcctgctt cgcgtccctt ttttaaacaa ataaagctgc
     9961 cataccccaa aaagaggata tgacagctat atatttttac tcagatagct ccaagaatct
    10021 tccgggcatt atcaatcctt tcctgcgtcg gaggattaac cccctccagt ggataagaaa
    10081 gccccagatt ctcccattta aacttaccaa gcgtatgata agggagcacc tccactctct
    10141 ccacattgga aagagtatgg ataaaatcag ctaaccggtg cagatattca tccttatcac
    10201 ttccgtccgg cacaagcaca tgacggatcc atacaggttt tttcatatca gaaagttccc
    10261 gcgccatcgc aagaatattc ttattggaat gaccggtaag cttaatatgc tcctgctcgt
    10321 caatctgctt gatatcaagc attacaagat ctgtatactt cataagctcc agccatccgg
    10381 aatgccatgg ttcctgatca gtgaagggat ttccactggt atcaagattc gtatgcacac
    10441 cctctgcctt tgccttctta aaaaattctg taagaaaatc catctgaagc aatggctcac
    10501 caccgcttac agtgataccg cctttgctgc cccagtagcc cttataacgt aaagctttct
    10561 taagaagctc atctgccgta taaagctctc cctgcttcat cttccaggta tccggattat
    10621 gacagaactg acatctcata gcacagccgc ttaaaaaaat cacatatctt actccgggtc
    10681 cgtcaacgga cccgaagctt tctaaagaat gaacatagcc ttttatctgt ttattatcca
    10741 ttatatcatc atccattaat tacattctgt cgtggcaggt tctggcaata acgtctaact
    10801 gctgctctct tgtaaggtcg atgaacttaa cagcatatcc ggatacacgg attgtgaagt
    10861 ttgcatactc ttctttttcc ggatgttcca tagcgtcgat cagtttctct ttaccaaata
    10921 cgtttacatt gaggtgatga gcaccctgat caaagtatcc gtcaagtaca tgtaccagat
    10981 tctctgaacg ctcgtcatca ctgtgtccca gagcatcagg attgattgtc tgagtattgg
    11041 agataccgtc aagagcatct tcatagtcaa gcttggcaac agagttcagg gaagcaagaa
    11101 gaccgttctg ctctgcaccg taagatgggt ttgcgccagg tgcaagaggt tcccctgctt
    11161 ttcttccatc cggaagagat ccagtagcct taccataaac aacgttggaa gtaatagtaa
    11221 ggatagatgt ggttggcttg gaatcacggt aagtatggat gtgtttcagt ttctcaagga
    11281 atgtagacag aagagttgtt gcaatctcgt ctgctctgtc atcatcatta ccataacgtg
    11341 ggaagtcacc ctcaacctgg aaatctgttg taataccgtc ttcatcgcgg atagctttaa
    11401 cttttgcata tttgatagcg gacagggagt ctactacatg agagaatcct gcgatacctg
    11461 ttgcgaaaga acgctcaacc tttgtatcga tcagagccat ctctgctgct tcgtagtagt
    11521 atttgtcatg catgtagtgg atcatgttca gtgttccgac atacagatga gccagccagt
    11581 ccatcatttt atcatatttt gcaattactt catcatagtc aagatattca gaagtgatcg
    11641 gctgatagtt tggtcctacc tgctgttttg tcttctcatc aacaccgccg ttgatcgcat
    11701 aaagaaggca ttttgcaagg tttgcacgag cgccgaagaa ctgcatctct ttacctgtct
    11761 ctgtagcaga tacacagcag cagatgctgt agtcatcgcc ccataccgga cgcataacat
    11821 catcattctc atactgaaca gaacttgttg taacagaaat atttgcagca tatttcttga
    11881 agttctcagg cagtcttgaa gaataaagta ctgtaaggtt tggttccgga gccggtccca
    11941 tatcttccag tgtgtgcagg aaacgatagt cgttctttgt taccatggaa cgtccgtcct
    12001 gtcccatacc tgctacttcc agagttgccc ataccgggtc accggagaat aactggttgt
    12061 aagaagggat acgtgcaaat ttaaccatac ggaatttcat taccatgtgg tcaacaagct
    12121 cctgagcttc tttctctgta agagttccgt tctgaagatc tctttcaata taaatatcaa
    12181 ggaatgtgga aatacgtccg acactcattg cagcaccgtt ctgagttttg atggctgcaa
    12241 gatatccgaa gtacagccac tggaaagctt ctcttgcatc tttggccggt ttggagatat
    12301 catatccata agattcagcc ataactttca tgcctttcag agcacggatc tgatcagcga
    12361 tctcttcacg aagctggaag tcataacgtc tcataccctg acggtcgcat gctgcgaagt
    12421 ctttctgttt tccttcgatc agagcgtcga ttccgtacag agccacacgt ctgtagtcgc
    12481 caacgatacg tccacgtccg taagtatccg gaagacctgt aaggatcttg ttgtgacgtg
    12541 ctactttcat ctcaggtgtg tagatatcaa atacaccctg gttgtgagtt ttaaattcat
    12601 agttgtggaa aacatcttta atcttgtcac ttactttata tccgtaagtt tcacaagcct
    12661 gctctgccat tttgataccg ccgtatggca tgaaagcacg tttcagaggt ttatctgtct
    12721 gaagaccaac aactttttca aggtcttttg tttcttcatc aatatatccg ggaccatatg
    12781 ctgtcagaga tgtaactacc tctgtctcca tatcaagaac tccgccttta gcacgttctt
    12841 ctttctgaag tgcctggagc ttgccccaca gtttgtttgt agcttctgta ggtccttcca
    12901 ggaaagaagc atcaccgtca tatggtgtat agttcattcc aataaagtta cgtacatcga
    12961 ttttttcttt ccaacggttg cccttaaagc cattccactg ttcgaaattt ttcattcttt
    13021 tacctctttc tctaaaatat ttccgcgcat ttctcactgg cctggagtga gataataaaa
    13081 tgtaaattgt acttatttag gacacttttc tgtccacgct gtcagtatac gtaaacatga
    13141 gtgttatgtc aattaatttc ccttatgatt ttaattaaat acaattctga tagcttttca
    13201 tcggagtttg cttctttatt gtactttatc gcgtacatta agactttctt gtatttttat
    13261 aaatacaaaa aaaataccgg tcaggaagtc ctctggacaa tctgaccggt atctgatttt
    13321 tgatatttta tgtaaactat attattccct gccaagcgga tattagcctg acctgcagaa
    13381 gtcaaaaaac agcaggaaaa aatcgggcgt gtcggaacaa tctaacggtt attgatcgct
    13441 gttacaagtg catcaataga tgcgcgaatg atatccgcgt ctacgcctgc accccaggca
    13501 agggttccat ccggcttttt gataccgaca taagcaatag ctttggaact tgaactgcgc
    13561 tccagcgcat gttcctgata tgtttccagg gaatatttca gctcatatgc cttcttcagt
    13621 gcattgctga ctgcatcaag acgtccgtta ccggatgcct ctgtagtgat tgtctttccg
    13681 cggaaagtag aggtaacttt tgttataata ccaccatctt tctgctggaa atgtacttca
    13741 ttgatgctgt acggttctgt gatattctca aaggtctgtt taaacagatt gaaaatttcg
    13801 tcaggatgaa gctctttatg tttgtggtct gaaacagctt ttgtggcata tcccattgct
    13861 tcacgcattt tcggaggaag attaagcccg aatttggtct caagaatata tcctacgccg
    13921 cctttgccgg actggctgtt gatgcggata acatctgcgt cataatttct tcccacatct
    13981 gtcgggtcga tcggaagata cggaacattc cagtgatccg gatccttgtc atctctccag
    14041 tgcataccct tggcaattgc atcctgatga gagccggaaa atgcggcaaa tacaagtgca
    14101 ccactgtacg gacttctttc gcctactttc attccggtac attcttcata tatttcacag
    14161 atatgcggca tatcagagaa gtcaagtttt ggatctacac cctgagaata catattcata
    14221 ccaagtgtaa caatatctac atttccggta cgctcaccgt ttccgaacag agtaccctcg
    14281 attctgtctg cacctgcaag taatcccatt tcagaatctg caacaccgca tcctctgtca
    14341 ttgtgcggat ggagagatac gattacattc tcgcggtatt tcagattttc acacatatat
    14401 tctacctggc ttgcatatac atgcggcatg gaatgctgta cagttacagg cagattgatg
    14461 atgcatttgt tatctgctgt aggctgccat acatcaagaa ctgcattgca tacttccaga
    14521 gcgtattccg gttctgtgcc tgtaaagctt tcagggctgt actcaaactg gaaatttcct
    14581 tctgtttcat cagccagttt ctttaataat gcggcaccat ccactgcaat ctttaagatt
    14641 tcttctttgg atttcttaaa tacctgttct ctctgagcta cagaggtgga attgtacaca
    14701 tgtacaattg ccttcggtgc gcctttgaca gcttcaaaag ttttgcggat gatatgctct
    14761 ctggcctgag tcagaacctg aatagttaca tcctgtggga tcagatgctg ctcgatcagg
    14821 gtacgcagaa attcatattc tgtttcagaa gcagccggga aacctacttc aatttctttg
    14881 aaaccgattt ttacaagaag tttaaagaat tcaattttct gttccagact catcggaatc
    14941 accagtgcct gattaccgtc acgaaggtct acagaacacc agacaggtgc tttgtccaca
    15001 tattcttttt ctgcccattt catgcattta acaggcggca taaaatactg tctctgatat
    15061 ttgcttggat tcatcatttt ttcttcctcc gttatgtaaa tattatgttt ggactgtggg
    15121 gattgactgt aaaaagacat aaaaaaatct tccatctcca cagacttatc tgcaagagac
    15181 gaaagatatt atcatcttac gcggtaccac tcttatttat gaacaatgtc atacactcat
    15241 gggatacgga atctccggat atccggtatt cttatatcct ctccatataa cggtggaaac
    15301 cgtctgcacc tactcttgta taatttcagg cagctgctca aaggcgagtt ccacaatttc
    15361 cttccactgc ttctcagcaa ccagcagttc tctgtgctcc ggtccgagtg tact
//
