LOCUS       c00017_gnlPro..        13153 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HFKDEBJH_17.
ACCESSION   c00017_gnlPro..
VERSION     c00017_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 18:39:30
            Original ID  :: gnl|Prokka|HFKDEBJH_17
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 53090
            Orig. end    :: 66243
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13153
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[63090:66034]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12944
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
     cand_cluster    1..13153
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /kind="single"
                     /product="Others_HGD_unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13153
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Others_HGD_unassigned"
                     /region_number="2"
                     /rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1,
                     HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and
                     minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2,
                     AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF,
                     ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C,
                     Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and not (minimum(2,
                     [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /tool="gutsmash"
     CDS             complement(2201..3337)
                     /locus_tag="ctg17_44"
                     /transl_table=11
                     /translation="MKFAHIGDLHIGKRVHDFSMLEDQRYILDQMMKIFAEQKVDGVLI
                     AGDVYDKTVPSAEAVQLFDEFITGLAKAEIPVYMISGNHDSAERLSFGAKLFESSDIYI
                     SQVYDGEMKRIVLKDQYGPISVYLLPFLKPAAVRHALQRDDINTYEEGVMAALQECEID
                     TTQRNVLVAHQFVTGADRSDSEETWVGGLDNVSAEVFKDFDYVALGHIHRPQKMGRETL
                     RYSGTPLKYSFSEADHKKSVTIVELLEKGNVRVSTVPLIPRRDMRKLRGTYMDVTAKDH
                     YTAENKMDYLQITLTDEEDVPGALQKLRTVYPNLMRLEYDNKRTRENREVQAVEVQEQK
                     SELELFEEFYELLNNEPMKEEQTEFVEKLIQDLKEVRV"
     CDS             complement(3405..4148)
                     /locus_tag="ctg17_45"
                     /transl_table=11
                     /translation="MLTEQRFDIILKLLEEKKSVTVTELRELLDASESTVRRDITALDK
                     AGKLTKVFGGAVALNHKVTAYEPTVAQKSELNKEEKQKIAKYAASLITPDDFVYLDAGT
                     TTGLMLEYLAGVRAAFVTNAVSHAQTLAKMGIRVYLIGGELKSSTEAVVGSQAMQMIQM
                     YHFTKGFFGTNGITRREGFTTPDTSEAIVKSTAMKQCKDVYILTDKSKFGEVSSVTFGG
                     FTDAKILTEEIPEEYQDSKNILKVK"
     CDS             complement(4443..4700)
                     /locus_tag="ctg17_46"
                     /transl_table=11
                     /translation="MKEFKYVVTDNEGIHARPAGELVKLVKGFESTISIEKEGKKVDCR
                     KLLALMGLGVKKGHEVTFTIEGADEEAAYEAVSKFMQDNL"
     CDS             complement(4760..6673)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTS_EIIC"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg17_47"
                     /sec_met_domain="PTS_EIIC (E-value: 4.9e-20, bitscore:
                     63.4, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRITDLLDRRSVSLTAAPKTKSETLDMAVDLMVKSEKISNREAYR
                     KQVYLREEESTTGIGEGIAIPHGKCDAVKKPGLAAMVIKNGVEFEALDDEPVTLLFLIA
                     APNTEDNIHLDVLSKLSVMLMDEEFTESLRNASSVDEFMDIIDRADSEKKDIDERLADT
                     GSTEGTQAKILAVTSCPTGIAHTYMAAEGIEKAAKAKNCFIKIETRGSGGAKNVLTDQE
                     IADADCIIVAADAKVPMERFDGKKVIECQVSDGISKADQLIDRAINGDAPVYHAAAGSQ
                     TSSAGNKSGGSVGHKIYMQLMNGVSHMLPLVVGGGILIAIAFLIDGLSVDLSALPADQR
                     ANFGTITPVAALFKGIGGTAFGFMLPILAGFIAMAIGDRPALALGLVGGMMAANGKSGF
                     LGALLAGFAAGYIILGLRKLCDKLPEALEKIAPVLIYPVVGILVMGLLMTFIVEPVMGG
                     INTGLNNALTGMGSSSKVILGIVLGGMMAIDMGGPFNKAAYVFGTAAIAAGNYDIMAAV
                     MIGGMTPPCAIALATLLFKDKFTKEERDAGPTNFIMGLAFITEGAIPFAASDPLRVLPS
                     CIVGSAVAGAISMAFDCTLMAPHGGIFVFPVVGNAVMYLVALVAGTVISAVLLGLLKKK
                     AA"
     CDS             complement(6691..7602)
                     /locus_tag="ctg17_48"
                     /transl_table=11
                     /translation="MIYTVTFNPSLDYIVSVDDFKLGLTNRTSSELMLPGGKGINVSTV
                     LMNLGIENTALGFTAGFVGKEIIRRLHEMGVKSEFIQISEGVSRINLKLKSIDGTEING
                     AGPVISKDKVEELMKKLEQLGEGDVLFLAGSIPSSMPDDMYEQIMARLDGKGVMIVVDA
                     TKDLLVNVLKYHPFLVKPNNHELGEIFGVELKTRKDVIPYGKKLQEKGARNVLISMAGE
                     GAVLVAEDGQVFEEPAPKGRLVNGVGAGDSMVAGFVAGWMEKKDYEHAFHMGIAAGSAS
                     AFSENLARKEEIEAVYRQITEK"
     CDS             complement(7922..9337)
                     /locus_tag="ctg17_49"
                     /transl_table=11
                     /translation="MWEAINSFLTTVDNLVWGVPLMVLIMAGGILLTARLGLLQMRRLP
                     LALKWMFKNEEEGDGEISSFAALCTALSATIGTGNIVGVATAVCAGGPGALFWMILAAF
                     FGMATKFSEGLLAVKYRVVAEDGHSLGGPFYYIEKGMGTKWKWLAKIFAFFGVCVGLFG
                     IGTFSQVNGISSAVQNFFDPNKSNCVNIPFLGEYSWAVVISSLILAACVAAILIGGLKR
                     IATVSQIIVPFMAVIYLIFSVALILLNITEIPAAIVTVVKGAFNPSAVTGGVVGTMIVS
                     MQKGVARGIFSNEAGLGSAPIAAAAAQTKEPVRQGLVSMTGTFIDTIVICTMTGLSIVL
                     TGAWQVEGLEGVQVTTYAFQHGLPIPGQISAFVLMICLVFFAFTTILGWDYYSERCLEY
                     LTNGHKKTILTYRWLYILAVFIGPYMTVSAVWTIADIFNGLMAIPNMIALFALSGVIVK
                     ETKAFFAAEKHKM"
     CDS             complement(10001..11680)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: BcrAD_BadFG"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg17_50"
                     /sec_met_domain="HGD-D (E-value: 6.8e-17, bitscore: 53.8,
                     seeds: 370, tool: rule-based-clusters)"
                     /sec_met_domain="BcrAD_BadFG (E-value: 4.7e-65, bitscore:
                     211.4, seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKTYYVCKYTPIELLESLGGECENFNHMPEGFDLADQVSHPNIC
                     GFGKTLLEGVMEGKIKELVLVSCCDTIRSVYDILLESGKLDFLYILDVLHCDSACSRER
                     MAVQLKGLAKAYAQYKGTEFDAGKFRAAFHAQEKITKSHIAVLGARMGQELFEMTSKAM
                     PLPVENDTCVHNRSVGNILPPEGASFDELMDWYAGEILGQIPCMRMMDPTGRKKLYNDP
                     SVAGIIYHTVKFCDFYSFEYAEIKNHTDVPLLKIESDYTIQSSGQLLTRLEAFAESIQP
                     ETLEQTIDGDTKGERKMGKGYFAGIDSGSTSTDVVILNKDHEIVTSIILPTGAGAAIGA
                     DRALAEALKEAGLQREDIDALVTTGYGRTAIKNGDKSITEITCHARGAHFLNPEVRTVI
                     DIGGQDSKVIRLDENGAVANFVMNDKCAAGTGRFLEMMARTMEMNLDQMSECGLEFKED
                     ITISSMCTVFAESEVVSLIAQNKATDDIVHGLNKAVAVKTAALTRRVGGEEKYMMTGGV
                     SKNKGLVKTLEEKLGTKLVISDKAQLCGALGAALFAADMADV"
     CDS             complement(11673..12944)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg17_51"
                     /sec_met_domain="HGD-D (E-value: 1.2e-55, bitscore: 181.2,
                     seeds: 370, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEIIETFGHYVENLTDKKPQSARRLLKTGWGAQNLKFRYMQDKRL
                     MPADRHLANLMMDTMLWPLQKPEDSVIVSIFTPCEMMQEVGLHPYNVEGFSCYLSASKA
                     ERAFLQQAENQGIAETLCSYHKTFLGAAQKGLLPKPKCIVYTNLTCDANLLTFRTLADF
                     YQVPVFAIDVPWNQTTENVQYVADQLKDLKIFLEKNTGKTISEDRLKERLACSKRTLEN
                     YKKYQQMRADRYVPSDLVTPLYAGMTNNILLGTAEEEKYTQMLLEDIKKAPAAKGKHIY
                     WMHTIPFWSDAVRQELCFSEKAQIVGCELAETCEPDFDPENPFEAMAERMVYHSLNGSA
                     LRRIEAGIRHAKQAGADGAVWFGHWGCKHTLGAAQLAKKKFEEAGLPLLILDGDGCDRS
                     HGGEGQTSTRLGAFLEMLGGAENE"
ORIGIN
        1 acattacagg tttccttttg atacactgtt tcactgctgt gatcctgtga cagttccgga
       61 tcagttttca tcctctgtct tgtatcttct tcatgaatcc atgtcagtac aggttcctcc
      121 aattggttct gcagctgttc ctggatactc tccagctgac tcttcctttt ttcaagactg
      181 atctgtaatt tctgaaattc ttttgcatgc tgttctgact gtgtgatgaa ctcttccttt
      241 ttcttcaaca gatcctgata agcttttttc tgtttttgaa tttcttctaa tcctgtctgt
      301 acactgcttt cctgattttt tacaaataaa cataattcat gatcaggaag ttcctttcga
      361 agtatctctt cggcttcctc ttgtggcaga aactgtgctg catagctttt aaccccttct
      421 gtcagttctt ccctgcaacg ctgcaccagt cctgctgcct ctcctgcctg cacacttgcg
      481 tcagatgcca ctttttctgc agcctctgtt aactttttct gttttttcag ctgttcttct
      541 gtgggaactt ccttcggaat ctgcgtaagc tttggatgat gaacagaacc acataccggg
      601 catggcatcc catcctgaag atctgctgcc agtatacctg cctgcgcatc cagataggcc
      661 tgctccattt tgtttaaaat ttcttttatt tctgtccgtt tctgagaagc ggtcagataa
      721 cccttctttt ttctctctgc ttccttttcc agatcctgat accgtttctg ctgatcttct
      781 attttctcta tctgctgcaa acgtatgacc agactgttct ctttgatttc cagattccca
      841 ccggaaacaa ttttctcttc cagatcagtc aaatcctttt ttatctgttt cgcaagttgt
      901 tcttcctgcc cggactgtat tttcagttca ctgatttttg tctgaagaaa ctccagattt
      961 ccacagttct tataaattcc tgcataaaga gtatctattt tctctttccg gaaatctgtt
     1021 tctgcttttt ctttttctgc accgtctgtt gtctgatatt ctttttgttt ttcttcaagc
     1081 acagctttca tttctttctg acgattctgt agctctgtac cgtccgttcc cagtttctct
     1141 atctgcaggg aagccttctc tgtttctctg agcagatttt ccagatttgt ataacgctcc
     1201 agattctctt tttctttctg tatggaaagc atcaggcgtt ggatctcctc aggttccttt
     1261 gccccatttt ctgcatcttt ttgtgcctgt tccaactgcg gaagcaatac ctctttctct
     1321 tgcagaagct gttccttcct tgcctttgca tctgcttctt tatgagcctt tcccaaaagc
     1381 tgatttactt tttccagttc tttatcgttc tctttgatct gcttattcaa atttttcagc
     1441 gtctctttat ctaccttcag aaactgctcc aggatttcca gaccttcttc cagatttccc
     1501 tcaaagccat tcttctccat caatatccac tgttgtccca actggtcttc tgtagaatat
     1561 ctgacctgtt ccgtatactg gcgaatactt ctcaacagct ctttatacgc cttgtccaga
     1621 ccaccggcct cgaattttaa tttttcctga atcaccttat aaatatccgt atggaaaagc
     1681 tttctgaaaa tgttgctgcg ttcctctgtg tcagccagca gcagtttcct gaaatctccc
     1741 tgtgcgatca tagcaatctg cgtaaactgc ttcatatcta acccgatcag atcagtaact
     1801 gtctgattca cttccttcag ctttgtcaca ggagctcttc catcagaaaa agtaagcaat
     1861 gcttcccctt tctgggtggt cattccggta cctctggtct ttgggcgctc ataatccggg
     1921 cttcgcttca ctgtatacac tgcatcttta tattcaaaaa tatattccgc atacgtaggt
     1981 gtttccggtt ttgcatactt acttctgagc atggatgcct cccggactcc tccgcttgtc
     2041 tccccataca acgcaaatgt aatcccatca aagatcgtcg tttttcccgc tcccgtatct
     2101 ccggtcacca gaaaaaggcc ctgtcctcca agctgtgtaa aatcgatcac agtctcatcc
     2161 gcatatggac caaatgcaga taatgtcaac ttcaatggtt tcatacgcgc acctccttca
     2221 gatcctggat cagtttttcc acaaactctg tctgctcttc tttcataggt tcattattta
     2281 acagctcata aaactcctca aacagctcca gctctgactt ttgttcctga acctccactg
     2341 cctgaacctc ccggttctca cgtgttcgtt tattgtcata ttccagacgc atcagattgg
     2401 gataaacagt acgcagcttc tggagtgccc ccggcacatc ttcctcatct gtcagagtaa
     2461 tctgaagata atccatctta ttttcagcag tataatgatc cttcgctgtc acatccatat
     2521 aggttcccct cagcttacgc atatcccgtc tgggaatcaa aggtactgta ctgaccctca
     2581 catttccctt ctccagaagc tccacaatcg ttaccgactt tttatgatct gcttccgaaa
     2641 aagaatactt aagcggcgtc ccactgtaac gcaaggtctc tctccccatt ttctgaggtc
     2701 tgtggatgtg tcccagtgcc acatagtcaa aatccttaaa tacttccgca ctgacattgt
     2761 caagaccgcc aacccatgtt tcttctgagt cacttctgtc tgctccggtc acaaactgat
     2821 gtgccaccag cacatttctc tgtgtcgtat cgatctcaca ctcctgcaga gcagccataa
     2881 caccctcttc ataagtatta atgtcatccc tctgcaaagc atggcgtact gccgcaggtt
     2941 tcaaaaaagg cagaagatat acagatattg gtccatactg atcttttaac acaatccttt
     3001 tcatctctcc atcataaacc tgcgaaatat aaatatcact gctttcaaac agctttgccc
     3061 caaaggaaag cctttctgct gaatcatgat ttccactgat catgtacaca ggaatctcag
     3121 ctttagccag tcctgtaata aactcatcaa acaactgcac tgcctctgcc gacggcactg
     3181 tcttatcata aacatcccct gcgattaaaa ctccatccac tttctgttcc gcaaagattt
     3241 tcatcatctg atccagaata tacctctgat cctccagcat ggaaaaatca tgcacccttt
     3301 ttccaatatg caaatcccca atatgcgcaa acttcatccc acatctctcc aatcttaata
     3361 tcattcctgc ctgctctgtc tgccggcggc atactgtcaa ttatttattt cactttcaga
     3421 atatttttgc tatcctgata ctcctccgga atttcttctg taagaatttt agcatctgta
     3481 aacccgccga atgtcacaga acttacttcg ccaaactttg acttatctgt cagaatatat
     3541 acatctttgc actgcttcat tgcagtactc tttacaattg cttcgctggt atccggtgtg
     3601 gtgaagcctt ctcttctggt gattccattt gttccgaaaa atccctttgt aaaatgatac
     3661 atctggatca tctgcattgc ctgactgcct acgactgctt ctgtggaact cttcagttct
     3721 cctccgatca aataaacccg gattcccatc tttgccagag tctgggcgtg ggatactgca
     3781 ttggtgacaa aggcagctct tacacctgcc agatattcca gcatcaggcc agtggtggtt
     3841 cctgcgtcca gataaacaaa atcatccggt gtgatcaggc tggctgcata ttttgcgatc
     3901 ttttgctttt cttctttatt taattctgat ttctgcgcta ctgtcggttc ataggcagtt
     3961 actttatgat ttaatgctac tgcaccgccg aaaaccttgg taagttttcc tgctttgtcc
     4021 aatgcagtaa tgtctctgcg cactgtggac tctgatgcat ccagaagttc tctcagttct
     4081 gttactgtaa cactcttttt ttcttccaga agcttcagaa taatatcaaa tctctgttct
     4141 gtaagcatgt acccctgcct ccattgtata tttgctttga ttgtttactt ctgattattt
     4201 tctccgatat ctacgaattg ctccgctgct tcgtagctcc cgcaattcta caaacattcg
     4261 gaatccgcag atttacttcg taaatcgcta cttcctcatg tttggcgggt cccaagttca
     4321 aaagtcttat cgtgcaagca cgaacgactt tctgcctttt gaccctgata tttcattata
     4381 acagaaacag gagatgaatg catcatctcc tgtctgtcag tttcttattt tattccgtaa
     4441 atttacaggt tgtcctgcat gaatttgctc actgcttcat atgctgcttc ttcatcagca
     4501 ccttcgattg tgaatgttac ttcatgacct ttcttaacgc caagtcccat cagtgcaaga
     4561 agttttctgc agtctacttt tttaccttct ttttcaatag agattgttga ctcaaatccc
     4621 tttaccagtt ttacaagttc tcctgcagga cgtgcgtgga ttccttcgtt gtctgtaact
     4681 acatacttaa attctttcat tttgatatcc tccatgttct ttattttaat tttttgttat
     4741 tgctttttta tttcgctgct tatgctgctt tcttctttaa cagaccaaga agaactgcag
     4801 agattactgt tcccgcaacc agtgcgacca ggtacataac tgcgtttcca accacaggga
     4861 atacgaaaat tccaccgtgt ggtgccatca gtgtacagtc gaatgccatg gaaatcgctc
     4921 ctgccaccgc agatcctacg atacaggaag gaagtacacg aagggggtca gatgctgcga
     4981 atggaatcgc accttctgtg ataaatgcaa gacccatgat aaagttggta ggacctgcat
     5041 ctctctcttc ttttgtgaac ttatccttaa acagcagtgt tgccagtgca attgcacagg
     5101 gaggtgtcat accgccgatc ataactgctg ccataatatc atagttacct gctgcaattg
     5161 cagctgttcc gaatacatat gctgctttgt tgaacggacc acccatatca atagccatca
     5221 ttccgccaag cacaatgcca agtattactt tactagaact tcccattcct gtcaaggcat
     5281 tattcagacc tgtgttgata ccgcccataa ccggctctac aataaatgtc atcaggagtc
     5341 ccataacaag gattccaact acaggataga ttaaaacagg agcgatcttt tccagggctt
     5401 ccggaagttt atcacataat ttacgaagtc caagaataat atatccggct gcaaagcctg
     5461 caagcaaagc tccaaggaaa ccagatttac cgttggctgc catcataccg cctaccagac
     5521 caagtgcaag tgccggtctg tcaccgattg ccattgcaat aaatccggca aggatcggaa
     5581 gcataaatcc gaatgctgta ccaccgatgc ctttaaacag agccgctacc ggagtaatgg
     5641 taccgaagtt tgctctctga tctgccggaa gcgcacttaa atctacactt aatccatcga
     5701 tcaggaacgc aatggcgatc aggataccac cgcctacaac caacggaagc atatgagata
     5761 cgccattcat cagctgcata tagatcttat gtcctacact gccgccggat ttgttaccgg
     5821 cagaagatgt ctgggaaccg gctgctgcgt ggtagaccgg tgcatcccca ttgattgctc
     5881 tgtcaatgag ctgatctgct ttactgattc cgtcggatac ctgacattcg atcacttttt
     5941 taccatcgaa acgttccatg ggaactttgg catctgctgc gacaataata cagtctgcat
     6001 cagcaatctc ctgatctgtc agcacattct ttgcaccgcc ggatccgcgg gtttcgatct
     6061 ttataaaaca gttctttgct tttgcagctt tttcaattcc ttctgctgcc atgtacgtat
     6121 gtgcgatacc ggtaggacaa gaagtaacag caaggatctt agcctgtgtt ccttctgttg
     6181 atccggtatc tgccagtctc tcatcaatat ctttcttttc actgtctgcc ctgtcaataa
     6241 tatccataaa ctcatctaca gacgatgcat tgcgaagaga ttctgtaaac tcctcatcca
     6301 tcagcatcac agagagcttg ctgagtacat ccaggtgaat gttatcctct gtattcggcg
     6361 ctgcgatcag gaataataag gttacaggtt catcatccag tgcctcaaac tctacaccat
     6421 ttttgatgac cattgccgca agtcccggct tcttaactgc atcacattta ccatgaggaa
     6481 tagcaattcc ctcgccaata cctgttgtgc tctcttcttc tcttaaatat acctgtttac
     6541 gataagcctc acgattgctg atcttctcac tctttaccat cagatcaact gccatatcca
     6601 gagtttctga ctttgttttc ggagcagctg ttaacgatac gcttcgtctg tcaagcaggt
     6661 ctgttattct catcttttct tcccccttta ttatttttcg gttatctgac gataaaccgc
     6721 ttctatttct tcctttcttg caagattttc agaaaatgca cttgcacttc ctgctgcaat
     6781 tcccatgtgg aatgcatgtt cgtaatcctt cttctccatc cagcctgcaa cgaatcctgc
     6841 taccatggaa tctcctgcac ccacaccatt taccagcctg ccttttggtg caggttcttc
     6901 aaatacctgt ccatcctctg ctaccagaac tgcaccttcg ccggccatgg agatcagcac
     6961 atttcttgca cctttttcct gaagtttctt tccataagga attacatctt ttcttgtttt
     7021 taattctaca ccgaagatct cgcccagttc atgattattt ggttttacaa ggaacggatg
     7081 atatttcaga acattgacca gaagatcctt tgtggcatca actacgatca tcacaccttt
     7141 tccatccagc cttgccatga tctgttcata catgtcatcc ggcatagaag atggaatgct
     7201 gcctgccagg aaaagtacat cgccttctcc aagctgttcc agtttcttca tcaattcctc
     7261 tactttatcc ttgctgatca ccggtcctgc accattgatc tcggttccgt caatagattt
     7321 cagtttcaga ttgatccttg aaaccccttc actaatttga atgaactcag attttactcc
     7381 catctcatgt aatctacgga taatttcttt ccctacaaac cctgcggtaa atccaagtgc
     7441 agtgttctca atcccaagat tcataaggac tgtggaaaca ttaattccct ttccccccgg
     7501 aagcatcagc tctgaacttg ttctgtttgt cagccccagt ttaaaatcat ctaccgaaac
     7561 gatgtagtcc agagatggat taaaagtcac tgtgtaaatc atctcttctt ttccctcctg
     7621 ttttatattg gtatcctttc ggagtcttta tttcacttgc accaaaagat tccaaaagta
     7681 catattgtca tgtcttttct gcatgttcgt gactgttttt tgtttacgtt cttagtatac
     7741 tgtcatattc gttcaaagtc aatcaaacta atccataaaa ataatgactg attttggttc
     7801 actttgcaca aaaaagtcat agtcagtcaa atgtaagcaa aaaaatcctc tgatcaggat
     7861 tgctataaat tccataatca gaggatttac tgttttctgt tattttatta cttttgattc
     7921 cttacatttt atgcttttct gctgcaaaga atgcttttgt ttcttttacg atcactccac
     7981 ttaatgcgaa caatgcgatc atattcggaa tcgccatcag tccgttgaag atatctgcga
     8041 tcgtccatac agcacttact gtcatgtacg gtccgataaa tactgccaga atgtaaagcc
     8101 agcggtatgt aaggattgtt ttcttatgtc cgtttgtcag atattccaga catctttcac
     8161 tgtaataatc ccatccaaga attgtagtaa atgcaaagaa taccagacag atcattaata
     8221 caaatgcaga aatctgtcca gggatcggaa gtccatgctg gaatgcatag gttgttacct
     8281 gaacaccttc cagaccttct acctgccatg cacctgtcag cacgatggaa aggcctgtca
     8341 ttgtacagat cacgattgta tcaataaatg taccagtcat gcttacaaga ccctgacgta
     8401 caggctcttt tgtctgagct gctgccgctg cgataggtgc gctaccaaga cctgcttcat
     8461 ttgaaaaaat accacgagcc acacctttct gcatggatac gatcattgtt cctaccacac
     8521 cgcctgtcac tgctgacgga ttaaaggctc ccttcacaac tgttacgata gctgccggga
     8581 tctctgtaat gtttaaaaga atcagcgcta cactgaagat cagatagatc accgccataa
     8641 acggtacaat aatctggctg actgttgcaa ttcgtttcag accaccgatg aggattgctg
     8701 caacacaggc tgcaagaatc agggaagaaa ttacaactgc ccaggaatac tctccaagga
     8761 acggaatatt tacacagttt gatttgttcg gatcaaagaa gttctgaact gcactggaaa
     8821 taccatttac ctggctgaat gtaccgattc cgaaaagacc tacacataca ccaaagaatg
     8881 caaagatctt tgcaagccat ttccattttg ttcccatacc tttctcaata taatagaaag
     8941 gaccgccaag gctgtgaccg tcttctgcta ccacacggta tttcactgca agaagacctt
     9001 cggaaaattt tgttgccatt ccgaagaatg ctgcaagaat catccagaat aaagctccgg
     9061 gacctccggc acagacagca gttgcaacac cgacgatatt accggttccg attgtggcgc
     9121 tcagtgctgt acataaagct gcaaaactgg aaatctcacc atcgccttct tcttcgttct
     9181 taaacatcca tttcaatgca agagggagtc ttcgcatctg aagaagtcca agtctggcag
     9241 ttaacaggat accacctgcc atgatcagga ccataagggg cacgccccag accagattgt
     9301 ctactgttgt caaaaaagaa ttgatcgctt cccacataat aataaatctc ctttttcttt
     9361 taaaaagtgt aatatattgt acagctggga aacaaagtaa taacagaccg tttcaaaaat
     9421 cagaagttca gaaaatactg ttcatatagt tcatatgaat cagcggggat gataaagcat
     9481 cctctgtcct tttgcctgag agattcaaga cacgaatcaa ataaccattt gtgggcagct
     9541 attgataatt cgtgttattt gcaccttcgg cccccgatct aacgggtgtc tccagagaaa
     9601 cgatccattt gcagttcttc cctgcatcca gggaacctga gagttttact ccttcggcgg
     9661 gtatagcctt ttatgtggct tcctctttcc tgcaaacttc acctcgttaa tttgctgtta
     9721 ctgtggtata ctatagctct taaatttgaa ctcgtcaata gaaaattaaa cttttataaa
     9781 aaaagtataa aaattgttac tgttcaccgg taatatccag caaggtattt tttgtgagcg
     9841 aaggtcacag aaaacccgag acataccgcg cgaatttatg cgattagcat aaattaagtt
     9901 tgcgaagcaa acgatactcc ttgggcattg cacaaggagg ttcatatttc ctgcatcgcg
     9961 aagcgtgttg ctgagaacgg agtgaacagt aactaaaaat ttacacatca gccatatcag
    10021 ccgcaaacag tgctgcgcca agtgcaccgc aaagctgagc cttgtcactg atcaccagct
    10081 ttgttccaag cttctcttcc agtgtcttta ccaggccttt attcttagaa acaccaccgg
    10141 tcatcatata tttctcctca ccgcccacac gtctggtaag ggcggcagtc tttacggcaa
    10201 ccgccttatt caagccatgg acaatatcat ctgttgcctt attctgggcg atcagggata
    10261 caacttctga ttctgcaaat actgtacaca tactggaaat tgtaatatct tctttgaatt
    10321 ccagcccaca ttcgctcatc tgatccagat tcatttccat ggtacgtgcc atcatttcca
    10381 gaaatcgtcc ggttcctgcc gcacatttgt cattcataac aaagtttgca actgcaccgt
    10441 tctcatccag tcggatcacc ttgctgtcct gtccgccaat atcaataaca gtacggactt
    10501 ccggattcag gaaatgcgca cctcttgcat gacaggtgat ctctgtgata ctcttatcac
    10561 catttttaat agctgtacgt ccgtatccag tagtaaccag cgcatcaata tcttctctct
    10621 gcaatccggc ctccttcaat gcctctgcaa gggcacggtc tgctccgata gcagctcctg
    10681 ctcctgtagg caagataatg ctggtcacaa tctcatgatc tttatttaaa atcaccacat
    10741 ctgtactggt agaaccactg tcaatccctg cgaaataacc ttttcccatt tttctctctc
    10801 cttttgtgtc tccatctatg gtctgctcca gtgtttcagg ctgaatgctc tctgcaaaag
    10861 cttccagtct ggtaagaagc tgaccgctgc tctgaatagt ataatctgat tcgattttta
    10921 aaagaggtac atctgtatga ttcttgatct cagcatattc gaagctgtaa aaatcacaaa
    10981 acttcactgt atgataaata atccccgcaa cagacggatc attataaagc ttcttacgac
    11041 ctgtcgggtc catcatacgc atacatggaa tctgccccag aatctcacct gcataccagt
    11101 ccatcagctc atcaaaagaa gcaccctccg gtggaagtat atttcccaca gaacggttat
    11161 gcacgcaggt atcattctct acaggaagag gcatagcttt gctggtcatt tcaaataatt
    11221 cctgccccat tctggcgcca agcactgcaa tatgggactt tgtgattttc tcctgtgcat
    11281 ggaaagcagc ccggaatttt ccggcatcaa actctgtgcc tttgtactgt gcataagcct
    11341 tcgccagccc ttttaactgt acagccatac gctctctgct acaggcactg tcacagtgaa
    11401 gcacatccaa aatatagaga aaatccagct tgccgctttc aagcagaatg tcatagacac
    11461 tccggatagt atcacagcag ctcaccagga caagttcctt gattttcccc tccatgactc
    11521 cttccagaag tgtttttcca aaaccgcaga tattgggatg tgaaacctga tcggccaggt
    11581 caaatccctc cggcatatga ttaaagttct cacattcccc gccaagagat tccagaagtt
    11641 caattggggt atatttacag acatagtaag ttttattcat tctcagcacc tcccagcatt
    11701 tccagaaaag ctcccagcct ggtggaagtc tgtccttctc ctccatggct tcgatcacac
    11761 ccgtcaccgt ccaggatcaa aaggggcaga ccggcttcct cgaacttctt ctttgcaagc
    11821 tgtgccgcac caagcgtatg tttacatccc caatgtccaa accacacagc accgtctgct
    11881 cctgcctgtt tcgcatggcg gataccggct tcaatccttc taagggcact tccgttcagt
    11941 gaatgatata ccattctttc tgccattgct tcaaaggggt tctcaggatc aaaatccggc
    12001 tcacaggttt ctgcaagttc acatcctacg atctgggctt tctcactgaa gcaaagctcc
    12061 tggcgcactg catccgacca gaatggaatg gtatgcatcc agtaaatgtg cttccctttc
    12121 gctgccggtg ctttcttaat atcttcaaga agcatctgtg tatacttctc ttcttctgct
    12181 gttcccagaa ggatattgtt tgtcattcct gcatacaagg gtgtgaccag atcagagggc
    12241 acatatctgt ctgcacgcat ctgctgatat tttttgtaat tctccagagt ccgcttactg
    12301 caggcaagac gttcctttaa tctgtcctca gagattgttt ttcctgtatt tttttccaga
    12361 aatattttta aatcctttaa ctgatctgcc acatactgta cattctctgt ggtctgattc
    12421 catggtacat caatggcaaa tacaggtacc tggtaaaaat ctgccagggt acggaaggtg
    12481 agcaggttag catcgcaggt caggttggta taaacaatac atttaggctt tggcagaagt
    12541 cctttctgcg ctgcaccaag aaatgtcttg tgataactgc acagtgtctc tgcaattccc
    12601 tgattctctg cctgctgcaa aaatgccctc tctgctttgc ttgcagaaag atagcaggaa
    12661 aatccttcta cattataggg atgtaatccc acctcctgca tcatttcgca gggtgtaaaa
    12721 atacttacaa taacagaatc ttccggtttc tgaaggggcc acagcatggt atccatcatc
    12781 aggtttgcaa gatgcctgtc tgcaggcatc agtctcttgt cctgcatgta acggaacttc
    12841 agattctgcg ccccccaacc ggtttttaac agccggcggg ctgactgagg ctttttatcc
    12901 gtcagatttt ccacataatg accaaatgtc tcaataatct ccatagtctg tctcttcctc
    12961 attatggtaa taataattta tcaattgtca gtgcacaaat agtgccacgg aatattttaa
    13021 taatatcttt ttgggaagtc aagttgaatt ttcgttactg ttcacacacc actattctgc
    13081 gaggtgtttt ggcatgaaca tgccaaaatc ccgagacata caagccaaaa ttccattgcc
    13141 gcaggcaatc tgg
//
