LOCUS       c00036_gnlPro..        15584 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HFKDEBJH_36.
ACCESSION   c00036_gnlPro..
VERSION     c00036_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 18:39:30
            Original ID  :: gnl|Prokka|HFKDEBJH_36
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15584
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..81
                     /locus_tag="ctg36_1"
                     /transl_table=11
                     /translation="VARTAGGREVAGSNPVAPTDIWLNRL"
     protocluster    1..15584
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2569:5584]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2570..5584
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..15584
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15584
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             431..2164
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HMGL-like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg36_2"
                     /sec_met_domain="HMGL-like (E-value: 7.6e-76, bitscore:
                     246.1, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEDFFMSFYSQSPQSKHNIYITEEEKMMNPSKYQRQYFMPPVKCM
                     KWAEKEYVDKAPVWCSVDLRDGNQALVIPMSLEQKIEFFKLLVKIGFKEIEVGFPAASE
                     TEYEFLRTLIEQNLIPQDVTIQVLTQAREHIIRKTFEAVKGAPKAIVHVYNSTSVAQRE
                     QVFKKSKEEILKIAVDGAALLKKLADETEGNFQFEYSPESFTGTEPEYALEVCNAVLDV
                     WQPTADNKCIINLPVTVQHSMPHVYASQVEYMCENLKYRENVIVSLHPHNDRGCGVADS
                     EMGLLAGADRIEGTLFGNGERTGNVDIVTLGMNMYSQGVDPKLDFSDMPHICEIYEECT
                     GMKVGERSPYSGALVFAAFSGSHQDAIAKGMHWRDDKDPDHWNVPYLPIDPTDVGRNYD
                     ADVIRINSQSGKGGVGYILETKFGLNLPPKMREAMGYATKAVSDHKHKELHPDEIFNLF
                     KQTFENITEPYSINEVHFQQKDGGIITKVTSTFRGKTITTEASGNGRLDAVSNALKKAY
                     ELKYSLETYQEHALERSSSSKAIAYVGIKKPDGTLAWGAGVDADIIRASIDALVTAINN
                     R"
     CDS             2570..4825
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg36_3"
                     /sec_met_domain="Gly_radical (E-value: 2.5e-41, bitscore:
                     131.6, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 5.1e-268, bitscore:
                     881.3, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNFEQWNGFKGNRWKEKIDVRNFIGMNYTPYDGDASFLEGPTEA
                     TNKLWGKLQALQKEERAKGGVLDMETEVVTSLTAYGPGYIDEETKDLEKVVGLQTDKPL
                     KRAFMPYGGIKMAEQACETYGYKVSDKIKDVFHNYEFKTHNQGVFDIYTPEMKVARHNK
                     ILTGLPDTYGRGRIVGDYRRVALYGIDALIEGKQKDFAACDRQGMRRYDFQLREEIADQ
                     IRALKGMKVMAESYGYDISKPAKDAREAFQWLYFGYLAAIKTQNGAAMSVGRISTFLDI
                     YIERDLQNGTLTEKEAQELVDHMVMKFRMVKFARIPSYNQLFSGDPVWATLEVAGMGQD
                     GRSMVTKNDYRFLHTLEDMGPAPEPNLTVLYSSRLPENFKKYAANISVTTSSVQYENDD
                     VMRPVWGDDYSICCCVSATETGKEMQFFGARANLAKCLLYAINGGVDEKTKQQVGPNYQ
                     PITSEYLDYDEVIAKYDKMMDWLAHLYVGTLNMIHYMHDKYYYEAAEMALIDTKVERSF
                     ATGIAGFSHVVDSLSAIKYAKVKAIRDEDGITTDFQVEGDFPRYGNDDDRADEIATTLL
                     STFLEKLKHIHTYRDSKPTTSILTITSNVVYGKATGSLPDGRKAGEPLAPGANPSYGAE
                     QNGLLASLNSVAKLDYEDALDGISNTQTINPDALGHSDDERSENLVHVLDGYFDQGAHH
                     LNVNVFGKEKLIDAMEHPEKEEYANFTIRVSGYAVKFIDLTREQQLDVIARTCHDRM"
     CDS             4829..5584
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 84.3;
                     E-value: 3.2e-26)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg36_4"
                     /sec_met_domain="Radical_SAM (E-value: 1.7e-27, bitscore:
                     87.8, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDDDIMDNKQIKGYVHSLESFGSVDGPGVRYVIFFSGCAMRCQFC
                     HNPDTWKMKQGELYTADELLKKALRYKGYWGSKGGITVSGGEPLLQMDFLTEFFKKAKA
                     EGVHTNLDTSGNPFTDQEPWHSGWLELMKYTDLVMLDIKQIDEQEHIKLTGHSNKNILA
                     MARELSDMKKPVWIRHVLVPDGSDKDEYLHRLADFIHTLSNVERVEVLPYHTLGKFKWE
                     NLGLSYPLEGVNPPTQERIDNARKILGAI"
     CDS             6011..8560
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AstE_AspA"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg36_5"
                     /sec_met_domain="AstE_AspA (E-value: 1.1e-32, bitscore:
                     104.2, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIITCIHGGWHKVKDLLSEIESYWTTRAEGYSEVNHKELNGMQKG
                     AWLEVLKGQFPEKAKDEIKILDIGTGPGFFPVILAEAGYKVTAVDYTQEMLDTAKRNAG
                     NLCERISFYKMDAQNLEFEDDVFDVVISRNLTWNLKDPKRAYEEWCRVLKPGGKLLNFD
                     ANWYGYLYDEEKRLSYEEDRKSVESEHLDDHYLCTDIDRMEKIALQMPLSSINRPSWDR
                     KFLKENGFESVAVDTGIWQRVWSQEEKLNYHSTPMFMISAVKKEKDIWSENDGMGDSDS
                     GYDRKRDLEDAMLCAAPGTKKSGFLKLGGGEFSLPYTVICGSHPGKTVLITAAVHGGEY
                     VGIQAAVELADKLKPEKIHGRVILVKTVCRKEFEERSGSVCPEDEKNLNRVFPGNPQGT
                     RMDRLAYEVVQKLHSAADYYIDLHSGDDYEQLTPYIYYAGCADEDVVQMSRKMAEQADV
                     PYMVKSNVASGGSYNYAAACGIPSVLIERGQMGGWSPEEVHSTRKDVRNILCALGVYDG
                     MRSYSNYYPMEIEDVRYQSASVSGLWYPAKKPGDIIKVGEYLGCVKDYEGNILETSLSD
                     LNGVVLYQAGSLQVIKDGPMIAYGSFSRRKDERKEKITNYWAKRSDSFMEQRRAELHSD
                     MADKWLKEIGTFLPDGKLRILDVGCGAGFFSILLAKLGHEVTGIDLTPDMIIHSRELAK
                     EENASCTFEVMDAENPDFPDGTFDVIVSRNLTWTLPDAARAYKEWIRVLKTGGILINAD
                     ANYGADDFSDTADLPVNHAHFTVGDAMMQECEEIKRQLPISSYVRPAWDLETLGKLGIN
                     RFSIDLGISSRIYTKKDEFYNPTPMFLICGEKNKCNN"
     CDS             8755..9591
                     /locus_tag="ctg36_6"
                     /transl_table=11
                     /translation="MKVQKKESKQSGNPARSLILVTVCTCTAIAFAAGGRIADFNGKNK
                     VYAASENREKTFSSDADETDVLPTGIAGVVSGMNDTASPKKSVTRIGTSCEQVMVGQRI
                     KVIEDNMAEFDVSSSMESSINELDARTAALAESARMMSDEDYDTLLHIVEAEAGTEDVK
                     GRILVANVIMNRIKNKEFPDTVTEVVWQNTNGVPQFSPTYDGRINEVTVTDETREAVRQ
                     ALEGVDYSEGALFFIQKSEAESQNVSWFEKDLKKLFKYGVHEFYTYPDSAESSTGS"
     CDS             9771..9920
                     /locus_tag="ctg36_7"
                     /transl_table=11
                     /translation="MCSIGEMNNCNCSAVYYYCQYTEQLRITLERQEISCRYYTKAQEE
                     KKKP"
     CDS             9875..11365
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg36_8"
                     /sec_met_domain="PALP (E-value: 2.2e-17, bitscore: 54.4,
                     seeds: 146, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQVLYKSTRGKEETVTASMAILKGLSEDGGLFVPTEIPKLDVPMD
                     ELAKMSYQETAYEVMKCFLTDFTEEELKNCINNAYDEKFDTKEIAPLHEADGAYFLELY
                     HGATIAFKDMALSILPHLMTTAAKKNQVKNEIVILTATSGDTGKAAMAGFADVPGTKII
                     VFYPKHGVSPIQEKQMVTQKGNNTYVVGITGNFDDAQTAVKKMFNDKDLEAELDAAGYQ
                     FSSANSINIGRLVPQIVYYVYAYASLVRQGKIKDGQEINVVVPTGNFGNILAAYYAKQM
                     GLPVHKLICASNDNKVLYDFFRTGTYDRKRDFILTTSPSMDILISSNLERLIYRIAGGD
                     AKKCAELMQSLTAGGEYTITEDMKAQLADFYGNYCTEDETAKTIAEIFKDSHYVIDTHT
                     AVAAGVYDKYVKDTNDTTPTVIASTASPYKFTRSVMEALGADTDGKDDFALADELSALS
                     GVKLPQAVETIRTAPVLHNRVVDAPDMPKAVKDILGIR"
     CDS             complement(11406..11522)
                     /locus_tag="ctg36_9"
                     /transl_table=11
                     /translation="MEIIGYCSHTLSREVFWHEYAKIPRHTSQNSIAAGNLE"
     CDS             11685..11918
                     /locus_tag="ctg36_10"
                     /transl_table=11
                     /translation="MSGRHYAAEDRRSVEDTHLAMARRQWEGNGISGTVKMSRREALFY
                     YLLDLILFYDTGGWKQWVFLKESSVYYRLGKQ"
     CDS             11867..12928
                     /locus_tag="ctg36_11"
                     /transl_table=11
                     /translation="MGVSERKFGVLQTGETVKIFHLENKSGAYAEVTDFGAILVKVCVP
                     DKDGTLTDVVLGYDDLASYEVNGCFFGSTIGRNGNRIGGAKFSVNGKEVVLAQNENDNN
                     LHSGPDGFEKKLWKVAEISDDKNSVIFNRISPDGENGFPGEFDVSVKYEFTEDNELRIH
                     YQGICDEPTVANMTNHSYFNLNGEGSGTAMDQYLTIHAKYYTPVADSHSIPTGVYEEVA
                     GTPMDFRTAKQIGQDIEAEFEQLKFTGGYDHNYVTDNYAKGNRRLIATAYSDKTGIAMD
                     VTSDCPCVQFYAANFVENEHGKNGHTYNKRDAFCLETQVEPNAVNVEDFHSPILNAGEQ
                     YDSVTAYHFYIRK"
     CDS             13160..14056
                     /locus_tag="ctg36_12"
                     /transl_table=11
                     /translation="MKKKNKTRSVTGLLFGFMERVSGDHVGAYATQAAYFLIMSFIPCI
                     LFLTTLVRYTPLTYNVVRDAIVAFIPENLQSFVLGIVVDVYKRSTAIVPLSAIVALWSA
                     GKGMQSIINGLNTIYHVKETRNWLLTRIYAVFYTLSLVIAVIVSLLMLVLGNEIQKAVS
                     RYIPFLGRVLGKILGARALLVFGVLFLVFLMLYKVLPNRKATFKSQIPGALIIAVAWSI
                     FSYGFSFYFEIFPGFSNMYGNLATIIMVMVWLYICMNLLLYGAEINAYFEKEFRIAHKS
                     VQELLAHEKEKKQQENE"
     CDS             14022..14126
                     /locus_tag="ctg36_13"
                     /transl_table=11
                     /translation="MKKKKSSRKMNEFWLRCEHDSQGAFYCKAFLSVL"
     CDS             14166..15044
                     /locus_tag="ctg36_14"
                     /transl_table=11
                     /translation="MIVVYLIFLAVIQAVMEFLPVSSLGHLCILEQYMGIGHETGLLSE
                     TMLHLGSAAAIIFLFRKDLKKIGLGLLGMFMDMIGNLNLYIHNKKTGENLGYARIVTGT
                     YRKTGALLVISMIPTALLGLTGKRLALLAADSQIVPGIGFLLTGVFLLVTDLNKSGGKK
                     GPREASYDSAMWIGICQGIAVFPGISRMGFTLCAALLCGYNRKFAVRFSVFMSLPAIIG
                     AFFTEIGNFGASEMTAGLGFTYVFAMIIAGFAGCLVIRNTIAMTQNIKLRYFAYYSFIV
                     GIITLALNFAL"
ORIGIN
        1 gtagcgcgca cggctggggg ccgtgaggtc gcaggttcaa atcctgttgc cccgactgac
       61 atatggttaa atcgtttgta gtatattttt acaatgaatg attcagacgt atgttcattt
      121 catttcaaaa aagccaaata aagttataag taaaatgcaa tgatagggaa tagtacactc
      181 ggaccggagc acagagaact gctggttgct gagaagcagt ggaaggaaat tgtggaactc
      241 gcctttgagc agctgcctga aattatacaa gagtaggtgc agacggtttc caccgttata
      301 tggagaggat ataagaatac cggatatccg gagattccgt atcccatgag tgtatgacat
      361 tgttcataaa taagagtggt accgcgtaag atgataatat ctttcgtctc ttgcagataa
      421 gtctgtggag atggaagatt tttttatgtc tttttacagt caatccccac agtccaaaca
      481 taatatttac ataacggagg aagaaaaaat gatgaatcca agcaaatatc agagacagta
      541 ttttatgccg cctgttaaat gcatgaaatg ggcagaaaaa gaatatgtgg acaaagcacc
      601 tgtctggtgt tctgtagacc ttcgtgacgg taatcaggca ctggtgattc cgatgagtct
      661 ggaacagaaa attgaattct ttaaacttct tgtaaaaatc ggtttcaaag aaattgaagt
      721 aggtttcccg gctgcttctg aaacagaata tgaatttctg cgtaccctga tcgagcagaa
      781 tctgatccca caggatgtaa ctattcaggt tctgactcag gccagagagc atatcatccg
      841 caaaactttt gaagctgtca aaggcgcacc gaaggcaatt gtacatgtgt acaattccac
      901 ctctgtagct cagagagaac aggtatttaa gaaatccaaa gaagaaatct taaagattgc
      961 agtggatggt gccgcattat taaagaaact ggctgatgaa acagaaggaa atttccagtt
     1021 tgagtacagc cctgaaagct ttacaggcac agaaccggaa tacgctctgg aagtatgcaa
     1081 tgcagttctt gatgtatggc agcctacagc agataacaaa tgcatcatca atctgcctgt
     1141 aactgtacag cattccatgc cgcatgtata tgcaagccag gtagaatata tgtgtgaaaa
     1201 tctgaaatac cgcgagaatg taatcgtatc tctccatccg cacaatgaca gaggatgcgg
     1261 tgttgcagat tctgaaatgg gattacttgc aggtgcagac agaatcgagg gtactctgtt
     1321 cggaaacggt gagcgtaccg gaaatgtaga tattgttaca cttggtatga atatgtattc
     1381 tcagggtgta gatccaaaac ttgacttctc tgatatgccg catatctgtg aaatatatga
     1441 agaatgtacc ggaatgaaag taggcgaaag aagtccgtac agtggtgcac ttgtatttgc
     1501 cgcattttcc ggctctcatc aggatgcaat tgccaagggt atgcactgga gagatgacaa
     1561 ggatccggat cactggaatg ttccgtatct tccgatcgac ccgacagatg tgggaagaaa
     1621 ttatgacgca gatgttatcc gcatcaacag ccagtccggc aaaggcggcg taggatatat
     1681 tcttgagacc aaattcgggc ttaatcttcc tccgaaaatg cgtgaagcaa tgggatatgc
     1741 cacaaaagct gtttcagacc acaaacataa agagcttcat cctgacgaaa ttttcaatct
     1801 gtttaaacag acctttgaga atatcacaga accgtacagc atcaatgaag tacatttcca
     1861 gcagaaagat ggtggtatta taacaaaagt tacctctact ttccgcggaa agacaatcac
     1921 tacagaggca tccggtaacg gacgtcttga tgcagtcagc aatgcactga agaaggcata
     1981 tgagctgaaa tattccctgg aaacatatca ggagcatgcg ctggagcgca gttcaagttc
     2041 caaagctatt gcttatgtcg gtatcaaaaa gccggatgga acgcttgcct ggggtgcagg
     2101 cgtagacgca gatatcattc gcgcatctat tgatgcactt gtaacagcga tcaataaccg
     2161 ttagattgtt ccgacacgcc cgattctgtc ctgctgtttt ttgacttctg caggtcaggc
     2221 taatatccgc ttggcaggga ataatatagt ttacataaaa tatcaaaaat cagataccgg
     2281 tcagattgtc cagaggactt cctgaccggt atttttttgt atttataaaa atacaaaaaa
     2341 gtcttaatgt acgcgataaa gtacaataaa gaagcaaact ccgatgaaaa gctatcagaa
     2401 ttgtatttaa ttaaaatcat aaaggaaatt aattgacata acactcatgt ttacgtatac
     2461 tgactgcatg ggcagaaaag tgtcctaaat aagtacaatt tacattttat tatctcactc
     2521 caggccagtg agagatgcgc ggaaatattt tagagaaaga ggtaaaagaa tgaaaaattt
     2581 cgaacagtgg aatggcttta agggcaaccg ttggaaagaa aaaatcgatg tacgtaactt
     2641 tattggaatg aactatacac catatgacgg tgatgcttct ttcctggaag gacctacaga
     2701 agctacaaac aaactgtggg gcaagctcca ggcacttcag aaagaagaac gtgccaaagg
     2761 cggagttctt gatatggaga cagaggtagt tacatctctg acagcatatg gtcccggata
     2821 tattgatgaa gaaacaaaag accttgaaaa agttgttggt cttcagacag ataaacctct
     2881 gaaacgtgct ttcatgccat acggcggtat caaaatggca gagcaggctt gtgaaactta
     2941 cggatataaa gtaagtgaca agattaaaga tgttttccac aactatgaat ttaaaactca
     3001 caaccagggt gtatttgata tctacacacc tgagatgaaa gtagcacgtc acaacaagat
     3061 ccttacaggt cttccggata cttacggacg tggacgtatc gttggcgatt acagacgtgt
     3121 ggctctgtac ggaatcgacg ctctgatcga aggaaaacag aaagacttcg cagcatgcga
     3181 ccgtcagggt atgagacgtt atgacttcca gcttcgtgaa gagatcgctg atcagatccg
     3241 tgctctgaaa ggcatgaaag ttatggctga atcttatgga tatgatatct ccaaaccggc
     3301 caaagatgca agagaagctt tccagtggct gtacttcgga tatcttgcag ccatcaaaac
     3361 tcagaacggt gctgcaatga gtgtcggacg tatttccaca ttccttgata tttatattga
     3421 aagagatctt cagaacggaa ctcttacaga gaaagaagct caggagcttg ttgaccacat
     3481 ggtaatgaaa ttccgtatgg ttaaatttgc acgtatccct tcttacaatc agttattctc
     3541 cggtgacccg gtatgggcaa ctctggaagt agcaggtatg ggacaggacg gacgttccat
     3601 ggtaacaaag aacgactatc gtttcctgca cacactggaa gatatgggac cggctccgga
     3661 accaaacctt acagtacttt attcttcaag actgcctgag aacttcaaga aatatgctgc
     3721 aaatatttct gttacaacaa gttctgttca gtatgagaat gatgatgtta tgcgtccggt
     3781 atggggcgat gactacagca tctgctgctg tgtatctgct acagagacag gtaaagagat
     3841 gcagttcttc ggcgctcgtg caaaccttgc aaaatgcctt ctttatgcga tcaacggcgg
     3901 tgttgatgag aagacaaaac agcaggtagg accaaattat cagccgatca cttctgaata
     3961 tcttgactat gatgaagtaa ttgcaaaata tgacaaaatg atggactggc tggctcatct
     4021 gtatgtcgga acactgaaca tgatccacta catgcatgac aaatactact acgaagcagc
     4081 agagatggct ctgatcgata caaaagttga gcgttctttc gcaacaggta tcgcaggatt
     4141 ctctcatgta gtagactccc tgtccgctat caaatatgca aaagttaaag ctatccgcga
     4201 tgaagacggc attacaacag atttccaggt tgagggtgac ttcccacgtt atggtaatga
     4261 tgatgacaga gcagacgaga tcgcaacaac tcttctgtct acattccttg agaaactgaa
     4321 acacatccat acttaccgtg attccaagcc aaccacatct atccttacta ttacttccaa
     4381 cgttgtttat ggtaaggcta caggatctct tccggatgga agaaaagcag gtgaacctct
     4441 tgctcctggc gcaaacccat cttacggtgc agagcagaac ggtcttcttg cttccctgaa
     4501 ctctgttgcc aagcttgact atgaagatgc tcttgacggt atctccaata ctcagacaat
     4561 caatcctgat gctctgggac acagtgatga cgagcgttca gagaatctgg tacatgtact
     4621 tgacggatac tttgatcagg gcgctcatca cctcaatgta aacgtatttg gtaaagagaa
     4681 actgatcgac gctatggaac atccggaaaa agaagagtat gcaaacttca caatccgtgt
     4741 atccggatat gctgttaagt tcatcgacct tacaagagag cagcagttag acgttattgc
     4801 cagaacctgc cacgacagaa tgtaattaat ggatgatgat ataatggata ataaacagat
     4861 aaaaggctat gttcattctt tggaaagctt cgggtccgtt gatggacccg gagtaagata
     4921 tgtgattttt tttagcggct gtgccatgag atgtcagttc tgtcataatc cggatacctg
     4981 gaagatgaag cagggagagc tttatacggc agatgagctt cttaagaaag ctttacgtta
     5041 taagggctac tggggcagca aaggcggtat cactgtaagc ggtggtgagc cattgcttca
     5101 gatggatttt cttacagaat tttttaagaa ggcaaaggca gagggtgtgc atacgaatct
     5161 tgataccagt ggaaatcctt tcactgatca ggaaccatgg cattccggat ggctggagct
     5221 tatgaagtat acagatcttg taatgcttga tatcaagcag attgacgagc aggagcatat
     5281 taagcttacc ggtcattcca ataagaatat tcttgcgatg gcgcgggaac tttctgatat
     5341 gaaaaaacct gtatggatcc gtcatgtgct tgtgccggac ggaagtgata aggatgaata
     5401 tctgcaccgg ttagctgatt ttatccatac tctttccaat gtggagagag tggaggtgct
     5461 cccttatcat acgcttggta agtttaaatg ggagaatctg gggctttctt atccactgga
     5521 gggggttaat cctccgacgc aggaaaggat tgataatgcc cggaagattc ttggagctat
     5581 ctgagtaaaa atatatagct gtcatatcct ctttttgggg gtatggcagc tttgtttttg
     5641 gtttaaaaag gggacgcgaa gcaggcgtat agttgtaccg gatacggttt cggcatctaa
     5701 gagattctaa gccctcgaaa atccgctaaa agcatgagac gaaaagtccg gaattactcg
     5761 ctgtcgctca gacaagggac ttttcgtctc ataacgcaga tttccgagga ctaagaatct
     5821 ctaagatgcc tgcaaatgca tccggtacaa ctatacgcct gcttcgctgg ttttggttaa
     5881 gatataatac aaggtggagt gtgaattata agaaggactt tgtttatata aaaatgaatt
     5941 gagacgtgaa atatatcccc cgggagggct tgttgggggg agggtggatt tgatataatt
     6001 ttgatcatat atgattataa cttgcataca tggaggttgg cataaggtga aggatttatt
     6061 atcggagatt gagagttact ggactacccg ggctgagggg tattctgaag ttaatcataa
     6121 ggaattaaat gggatgcaga agggggcatg gcttgaggtg ttgaaagggc agttcccgga
     6181 gaaagcgaag gatgagatta agattttgga tatcggaaca ggacctggat tttttcctgt
     6241 tattctggct gaggcgggat ataaggtgac tgctgttgat tatacgcagg agatgttgga
     6301 taccgcgaag aggaatgccg gtaatctttg tgagcggatt tctttttata agatggatgc
     6361 tcagaatctg gaatttgagg atgatgtgtt tgatgttgtg atcagcagga atctgacatg
     6421 gaatctgaag gatcctaaga gagcttatga agagtggtgt cgtgtactga aaccgggcgg
     6481 aaagcttctt aatttcgatg caaactggta cggttatctt tatgatgagg agaaacgcct
     6541 gtcttatgag gaagaccgaa agagtgtgga gagtgagcat ctggatgatc attacctctg
     6601 tacggatatt gacagaatgg agaagattgc actgcagatg cctctttctt ctattaacag
     6661 accgtcctgg gacaggaagt ttctgaagga gaacgggttt gagtctgtgg cagtggatac
     6721 cgggatctgg cagcgggtgt ggagtcagga agagaagctg aattatcatt ctacgccgat
     6781 gtttatgatc agcgctgtga agaaagagaa agatatctgg tccgagaatg atggaatggg
     6841 tgattctgat agcggatatg acaggaaaag agatttggag gatgccatgc tgtgtgctgc
     6901 tccgggtacg aaaaagagcg gattcctgaa actgggcgga ggtgagtttt cgcttcctta
     6961 tacagtaatc tgcggttctc atcccggaaa gacagttctg atcaccgctg cggtccatgg
     7021 aggagaatat gtgggaatcc aggctgctgt tgagcttgcg gataagctga aaccggagaa
     7081 gatccatgga agagtgattt tggtcaagac tgtgtgcagg aaggaatttg aggagaggag
     7141 cggcagtgtc tgcccggagg atgagaagaa tctgaatcgt gtatttccgg ggaatccgca
     7201 gggaaccagg atggaccgtc tggcgtatga ggtggttcag aagcttcaca gtgcagcaga
     7261 ttattatatt gatcttcaca gcggggatga ttatgagcag cttacgcctt atatttacta
     7321 tgccggatgt gcagatgaag atgtggttca gatgtcaagg aagatggcag agcaggcaga
     7381 tgttccctat atggtaaagt ctaatgtggc atccggtggt tcttacaatt atgctgccgc
     7441 atgtggcatt cccagtgttc tgatcgaacg tggccagatg ggaggctgga gtccggagga
     7501 ggttcattct acaagaaaag atgtgcgtaa tattctgtgt gcgctgggtg tttacgatgg
     7561 catgagaagt tacagtaatt attatcccat ggaaattgaa gatgtgcgtt atcagtctgc
     7621 cagtgtatcc gggctgtggt atcctgccaa aaaaccggga gatattatta aggttggaga
     7681 gtatcttggc tgtgttaagg attatgaggg aaatattctg gagacaagtt tatccgattt
     7741 aaatggagtg gttctatatc aggcgggaag tcttcaggtt attaaggatg gtccgatgat
     7801 cgcatatggc agtttcagca gaagaaagga tgaacgcaag gaaaagatca caaattactg
     7861 ggcgaaaaga agcgacagtt ttatggaaca gagaagagct gagcttcaca gtgatatggc
     7921 tgataaatgg ctgaaagaga tcgggacttt tcttcctgat ggaaaattaa ggatcctgga
     7981 tgtgggatgc ggtgcaggct tcttttccat tcttttagca aaactgggac atgaagttac
     8041 aggaatcgat ctgacaccgg atatgatcat tcattccagg gaactggcaa aagaagagaa
     8101 cgcctcctgt acgtttgaag taatggatgc ggaaaatccg gattttcctg atggtacctt
     8161 tgatgtgatc gtgtccagaa atcttacctg gacacttccg gatgcagcaa gagcatataa
     8221 agaatggatt cgtgtgctga aaacgggagg aatcctgatc aacgcagatg ccaattatgg
     8281 tgcagatgat ttctcagata ctgctgatct gcctgtcaat catgctcatt ttacagtagg
     8341 cgatgccatg atgcaggaat gcgaggaaat taaacgccag cttcctatca gttcctatgt
     8401 acgccctgcc tgggatctgg agacactggg aaaactgggt atcaacagat tctccattga
     8461 tctgggtatc agcagcagaa tttatacaaa gaaagatgag ttttataatc caacccctat
     8521 gttcctgatc tgcggcgaaa aaaataaatg taataattga gaaaaatgaa gcatatatta
     8581 aagggagatt tcattaatgg aaccttcctt ttttcttttt tgcaagctaa aatgttacaa
     8641 aaatatgaaa aaagcttgac aaaatcaatt atattaaata taattttctt ataagttaca
     8701 gaaatgttac agccataaaa acctgtaatt aaaaaaactc aaggaatgat aagtatgaaa
     8761 gttcagaaaa aagagtcaaa acagtccggc aatccggcgc ggagtctgat actggttaca
     8821 gtgtgtacct gtacggcgat tgcgtttgca gcaggcggca gaatagcaga ttttaatgga
     8881 aaaaacaaag tatatgcagc ttctgaaaat agggagaaaa ctttttcctc tgatgctgac
     8941 gaaacagatg tactgccaac aggaattgca ggagtagtat ccggaatgaa tgatacagct
     9001 tctcccaaaa aatcagtcac acgtatcgga acttcctgtg aacaggtaat ggtcggtcag
     9061 agaattaaag ttattgaaga taatatggca gaattcgatg tcagctcttc tatggagagc
     9121 agcatcaatg agttggatgc aaggacagcg gctcttgcag agagcgcccg gatgatgtcg
     9181 gatgaggact atgatacatt gcttcatatt gtagaggctg aagcaggtac tgaggatgtc
     9241 aagggacgca ttctggttgc caatgtgatc atgaaccgta taaagaataa ggaatttccc
     9301 gatacagtca cagaagtggt atggcagaat accaatggtg ttccgcagtt ttcaccgact
     9361 tatgacggac gtatcaatga agtaactgtt acagatgaga caagagaagc cgtcagacag
     9421 gctcttgaag gtgtggatta ttcagaagga gcactgtttt ttatccagaa gtctgaagct
     9481 gaaagccaga atgtctcctg gtttgagaaa gatctgaaaa agctgtttaa atacggcgta
     9541 catgaatttt atacctatcc ggattcagca gaaagttcca caggatcgta ataaacgata
     9601 ctcttcatat aactcattta acaggattgc ggtaatactg ctcaaaatat ggacatattc
     9661 ttcgggaaca aaagaatatg tccatatttt tgatttatag taatcaatca taaaaagaca
     9721 gaaaaaagag aaataattta ggatagtatt ttgctaaagt atatgctata atgtgctcaa
     9781 ttggcgaaat gaataactgt aactgttcag cggtttatta ttactgccaa tatactgaac
     9841 agttacgaat aactttggaa aggcaggaaa tatcatgcag gtattataca aaagcacaag
     9901 aggaaaagaa gaaaccgtaa cagcttctat ggctatttta aaggggcttt ctgaggatgg
     9961 cggcttattt gtgccgacag agattccgaa gctggatgtc ccaatggatg agctggcaaa
    10021 gatgagctat caggagacag catatgaagt aatgaaatgt ttccttactg attttacaga
    10081 agaagaatta aagaactgca tcaacaatgc ctatgatgaa aaatttgata caaaagagat
    10141 tgcaccgctt catgaagcag acggagctta tttccttgag ctgtatcatg gtgcgaccat
    10201 tgcgtttaag gatatggcat tatcaattct tccacatctt atgactacag ctgctaagaa
    10261 gaatcaggta aagaatgaga ttgttattct taccgctact tccggagata caggtaaagc
    10321 ggcaatggcc ggatttgcag atgttccggg aaccaagatc atcgttttct atccgaaaca
    10381 tggtgtaagt cctatccagg agaaacagat ggtaactcag aaaggcaaca atacatatgt
    10441 tgtgggaatt accggaaact ttgacgatgc acagactgcc gtaaagaaaa tgttcaatga
    10501 taaggacctg gaagcagaac ttgatgctgc aggatatcag ttctcatctg cgaactctat
    10561 caatatcgga cgtctggtac cgcagatcgt ttattatgta tatgcatatg catcacttgt
    10621 acgtcagggc aagatcaaag acggtcagga gatcaatgtg gtagtaccta ccggaaactt
    10681 tggaaatatc ctggctgctt attatgcaaa acagatggga cttccggttc acaaacttat
    10741 ctgtgcctcc aatgataaca aggttctgta tgatttcttc cgcacaggaa cttatgacag
    10801 aaagcgtgac tttatcctta caacctcacc atccatggat attctgatct ccagcaatct
    10861 ggaacgtctg atctaccgta tcgcaggcgg tgatgcaaaa aaatgtgcag agctgatgca
    10921 gtctcttact gctggcggcg agtataccat cacagaagac atgaaggcac agcttgcaga
    10981 cttctatggc aattactgta cagaagacga aacagcaaaa acaatcgcag aaatcttcaa
    11041 agacagtcat tatgtgatag atacccatac tgcagttgca gcaggtgttt atgacaaata
    11101 tgtaaaagat accaatgata ccacaccaac tgtcattgca tccacagcaa gcccatataa
    11161 atttacaaga agtgtaatgg aagcacttgg agcagataca gacggtaagg atgattttgc
    11221 actggctgat gaactgagtg cgctttccgg agtgaaactt ccacaggcag ttgagacgat
    11281 ccgcacagca ccggtgcttc ataaccgggt ggtagatgcg ccggatatgc caaaggcagt
    11341 aaaagatatc cttggaatcc gataatcgtt actgttcact ccgttcacag taacgtagcc
    11401 aaaattcatt ccagattgcc tgcggcaatg gaattttggc ttgtatgtct cgggattttg
    11461 gcatattcat gccaaaacac ctcgcgggat agtgtgtgtg aacagtaacc gataatctcc
    11521 atattataaa aaatataatt aattctacat tttatgttga aaaagaacat atactggagt
    11581 ataataaaaa tcagttaaaa acagtgaata tcctgaaatg tacgaggccc cttctttttt
    11641 tgaacctaca tcgactttaa cgggaaccca acatcgcagg ccggatgtca ggccgtcatt
    11701 atgcagcgga agacagaagg tctgttgagg atacccacct agctatggct aggcgtcaat
    11761 gggaagggaa cggcatttcg ggaactgtaa aaatgagccg tagagaggct cttttttatt
    11821 atcttttgga tttaatatta ttttatgata cgggaggttg gaaacaatgg gtgtttctga
    11881 aagaaagttc ggtgtattac agactgggga aacagtaaaa atttttcatc tggaaaacaa
    11941 atccggggca tatgcggaag tgacagattt tggagcaatc ctggttaagg tctgcgtacc
    12001 tgataaagat ggtactttaa cagacgtagt acttggatat gatgatctgg catcttatga
    12061 agtaaatgga tgctttttcg gttcaaccat cggcagaaac ggaaaccgca tcggcggtgc
    12121 gaaattctct gtcaatggca aagaagtagt tcttgctcag aatgagaatg acaataatct
    12181 tcacagcggt cctgacggat ttgaaaaaaa gctctggaaa gtggctgaga tttccgatga
    12241 taaaaacagt gttatattta accgtataag tccggatggc gagaatggtt tcccgggaga
    12301 atttgatgtg tctgtaaaat atgagtttac ggaagacaac gaactgagga tccattatca
    12361 gggaatctgc gatgagccga cagttgccaa tatgacaaat cattcttatt tcaatctgaa
    12421 tggtgaggga agcggaaccg ccatggatca gtatcttaca atccatgcaa aatattatac
    12481 acctgtagcc gacagtcatt ccattcctac aggagtgtat gaggaagttg cagggactcc
    12541 catggatttc agaactgcca aacagattgg gcaggatatt gaagcagaat ttgagcagct
    12601 gaaattcaca ggcggatatg accacaatta tgtgacagac aattatgcaa aaggaaacag
    12661 aagactgatc gcaaccgcat acagtgataa aaccggaatt gccatggatg tcacttccga
    12721 ctgtccatgt gtacagtttt acgcagcaaa ttttgtcgaa aatgaacatg gtaaaaatgg
    12781 tcatacttac aataagcggg atgctttctg tctggaaacg caggttgaac cgaatgcggt
    12841 caatgttgaa gatttccact ccccgattct taatgcaggt gaacagtatg attctgtgac
    12901 tgcttatcat ttctacatca gaaagtaaaa atctgaccat aaaactaatt acatattgat
    12961 ccggtttttt tcatatctac agcgttccag catgaaaaga accggatttt attatccata
    13021 attcatgttt gtcataacgg cagtttcatg gtatgatagt aaacagagat attcgaaaca
    13081 gttatcttta taattacagc aatcaccata aatgcattat ctaaaatgac tgctgtaaaa
    13141 taacagaatg gagacatata tgaaaaagaa aaataaaacc cggtctgtta cagggctttt
    13201 attcgggttt atggaacgtg tatccggaga tcacgtagga gcttatgcga cacaggcagc
    13261 gtattttctg atcatgtctt ttattccctg tattctgttt ctgactacac tggtacggta
    13321 tacacctctg acctataatg tagtcaggga tgcgatcgtt gcttttattc cggagaatct
    13381 gcagagtttt gttctgggga tcgtggtaga tgtatacaaa agaagtactg caattgtccc
    13441 tttgtcagca attgtggcac tgtggtctgc cggaaaagga atgcagtcta tcatcaatgg
    13501 attaaatacc atttatcacg taaaagaaac ccgtaactgg ctgttaacca gaatttatgc
    13561 agtattctat actttatcac tggtgattgc ggtaatcgtg tctctgctta tgcttgtact
    13621 cggaaacgaa atacagaaag ctgtatcaag atatattcct tttcttggaa gagttctggg
    13681 aaaaatactg ggggcaagag cactgttggt atttggtgtg ttgtttctgg tttttcttat
    13741 gttgtataag gttcttccga acagaaaagc cacattcaaa agccagattc ccggagcctt
    13801 gatcatagca gttgcatggt cgatattttc atacggattc tctttttatt ttgagatttt
    13861 tccggggttc agtaatatgt acggaaacct tgcgacgatc atcatggtca tggtgtggtt
    13921 gtatatctgt atgaatcttc tgttatacgg tgcagagatc aatgcttatt ttgaaaaaga
    13981 attccggatt gcacataaat cggtacagga actgctggca catgaaaaag aaaaaaagca
    14041 gcaggaaaat gaatgaattt tggctacgtt gtgaacatga cagtcagggg gctttttatt
    14101 gtaaagcctt tctgagtgtg ctataataaa ccataatttt ggagaaacaa aaaggaatca
    14161 gttctatgat cgttgtatat ttgatatttt tggctgtcat tcaggctgtg atggaatttc
    14221 ttcctgtcag cagcctggga catttatgca tattggaaca atatatggga atcggccacg
    14281 aaaccggatt gctgtcagaa acgatgctcc atcttggaag tgcggcagca attatatttt
    14341 tgttccgcaa agatttaaaa aaaatcggac tgggacttct ggggatgttt atggatatga
    14401 tcggtaatct gaatctatat atccataaca agaagacagg ggaaaatttg ggctatgcca
    14461 gaatagtcac cggaacatat cggaaaacag gtgcacttct tgtgatttcc atgattccaa
    14521 cagcacttct gggacttaca ggaaaacggc tggctcttct ggccgcagac tctcagattg
    14581 ttccgggaat cggattttta cttacaggcg tatttcttct ggtaacagat ctgaataaat
    14641 ccggtggaaa aaagggaccg agagaggctt cttatgacag cgccatgtgg attggaattt
    14701 gtcaggggat tgctgtcttt ccagggattt ccagaatggg atttacgtta tgtgctgcac
    14761 tgttatgcgg atataaccgc aaatttgcgg ttcgtttttc tgtttttatg agtctgcctg
    14821 ctatcatagg tgcttttttt acggaaatcg gaaattttgg tgcttctgaa atgacggcag
    14881 gacttgggtt tacctatgta tttgcaatga tcatcgccgg ttttgcggga tgtcttgtta
    14941 tccgaaatac aatagccatg actcagaata taaaattacg ctattttgca tattattcat
    15001 ttatagtcgg tattattaca ctggcattaa attttgccct gtaaagggaa gatatttacg
    15061 agaagatcaa ggaggggagc cttagaatgg cagcatcaaa gagtaagaat accgggcatt
    15121 cgggaagaaa tacaaaaaag aagacagcaa tggaacagga agtcggcaga tttcagacag
    15181 aaatcatatt atttgtgatt ttggccgcat gtgtgatcct gatggcaagc aattttggag
    15241 caggtggttt tgtgggagat gcgatcagta atttctgttt cggactgatg ggactgatgg
    15301 catatctgtt tccaatcgta tttttccttg aatcagcatt tattctgatc aataaaacaa
    15361 accggctggc atataagaaa cttgcagcgg cgtttgtgat gtttctgttt ctgtgtgggg
    15421 cagcgcagct tctcacagac ggatatatgc agagtacaac tttgctggat tattatgctt
    15481 taagcgcaga ttataaaaca ggcggtggtc tgatcggagg agcgatctgt atttctgtca
    15541 catctgcttt tggaactatc ggcggatatg tgatcattat actg
//
